ZNF830

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.48918637
2viral transcription (GO:0019083)4.46905354
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.41987257
4translational termination (GO:0006415)4.36537700
5ribosomal large subunit biogenesis (GO:0042273)4.35942808
6proteasome assembly (GO:0043248)4.27698624
7pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.04809486
8ribosomal small subunit biogenesis (GO:0042274)3.98875892
9establishment of protein localization to mitochondrial membrane (GO:0090151)3.87984094
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.85105063
11chaperone-mediated protein transport (GO:0072321)3.83890225
12cotranslational protein targeting to membrane (GO:0006613)3.80811173
13CENP-A containing nucleosome assembly (GO:0034080)3.78155242
14protein targeting to ER (GO:0045047)3.75578440
15translational elongation (GO:0006414)3.72078819
16ATP synthesis coupled proton transport (GO:0015986)3.68919207
17energy coupled proton transport, down electrochemical gradient (GO:0015985)3.68919207
18chromatin remodeling at centromere (GO:0031055)3.68213624
19exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.62609413
20regulation of mitotic spindle checkpoint (GO:1903504)3.59644603
21regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.59644603
22nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.58529639
23translational initiation (GO:0006413)3.57251674
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.56745997
25protein localization to endoplasmic reticulum (GO:0070972)3.52287400
26pyrimidine nucleotide catabolic process (GO:0006244)3.50558784
27nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.45494359
28spliceosomal snRNP assembly (GO:0000387)3.43514767
29ribonucleoprotein complex biogenesis (GO:0022613)3.38947962
30viral life cycle (GO:0019058)3.35924643
31cellular protein complex disassembly (GO:0043624)3.33559920
32protein-cofactor linkage (GO:0018065)3.26098393
33maturation of SSU-rRNA (GO:0030490)3.21474011
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.17602429
35platelet dense granule organization (GO:0060155)3.15219613
36rRNA processing (GO:0006364)3.14507509
37translation (GO:0006412)3.12741844
38histone mRNA metabolic process (GO:0008334)3.12563613
39cellular component biogenesis (GO:0044085)3.10782490
40histone exchange (GO:0043486)3.10352439
41rRNA metabolic process (GO:0016072)3.07144149
42negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.05231080
43termination of RNA polymerase III transcription (GO:0006386)3.02895539
44transcription elongation from RNA polymerase III promoter (GO:0006385)3.02895539
45DNA deamination (GO:0045006)3.01422693
46cullin deneddylation (GO:0010388)3.01288679
47mitotic metaphase plate congression (GO:0007080)2.99101723
48pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.98947916
49nuclear-transcribed mRNA catabolic process (GO:0000956)2.97960653
507-methylguanosine RNA capping (GO:0009452)2.95247920
51RNA capping (GO:0036260)2.95247920
52base-excision repair, AP site formation (GO:0006285)2.94442537
53DNA replication-independent nucleosome organization (GO:0034724)2.92433759
54DNA replication-independent nucleosome assembly (GO:0006336)2.92433759
55protein deneddylation (GO:0000338)2.91399340
56protein K6-linked ubiquitination (GO:0085020)2.89490069
57mitochondrial respiratory chain complex I assembly (GO:0032981)2.89238836
58NADH dehydrogenase complex assembly (GO:0010257)2.89238836
59mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.89238836
60DNA catabolic process, exonucleolytic (GO:0000738)2.87148571
61oxygen transport (GO:0015671)2.85840965
62rRNA modification (GO:0000154)2.85812762
63regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.83438965
64protein targeting to mitochondrion (GO:0006626)2.83360690
65respiratory electron transport chain (GO:0022904)2.81675497
66protein complex biogenesis (GO:0070271)2.81607045
67mitochondrial respiratory chain complex assembly (GO:0033108)2.81273748
687-methylguanosine mRNA capping (GO:0006370)2.80944058
69DNA replication checkpoint (GO:0000076)2.80868986
70mRNA catabolic process (GO:0006402)2.80441331
71male meiosis I (GO:0007141)2.79295181
72positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.78141676
73cellular response to zinc ion (GO:0071294)2.77954788
74negative regulation of ligase activity (GO:0051352)2.76935509
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.76935509
76anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.76508097
77electron transport chain (GO:0022900)2.75882484
78protein complex disassembly (GO:0043241)2.75017336
79mitochondrial DNA replication (GO:0006264)2.70413361
80RNA catabolic process (GO:0006401)2.70231229
81protein localization to mitochondrion (GO:0070585)2.69979278
82mitotic G2/M transition checkpoint (GO:0044818)2.67903755
83ribosome biogenesis (GO:0042254)2.66833180
84synapsis (GO:0007129)2.65387063
85DNA strand renaturation (GO:0000733)2.64693559
86positive regulation of B cell differentiation (GO:0045579)2.63710194
87protein neddylation (GO:0045116)2.62598047
88DNA ligation (GO:0006266)2.62514044
89pseudouridine synthesis (GO:0001522)2.61341461
90macromolecular complex disassembly (GO:0032984)2.59945891
91DNA damage response, detection of DNA damage (GO:0042769)2.59907353
92establishment of protein localization to mitochondrion (GO:0072655)2.59118726
93metaphase plate congression (GO:0051310)2.58400433
94telomere maintenance via telomerase (GO:0007004)2.56304723
95kinetochore organization (GO:0051383)2.54467098
96intra-S DNA damage checkpoint (GO:0031573)2.53433571
97replication fork processing (GO:0031297)2.52306616
98kinetochore assembly (GO:0051382)2.52150518
99rRNA methylation (GO:0031167)2.51778281
100nucleotide-excision repair, DNA gap filling (GO:0006297)2.51027729

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.79014065
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.56663690
3EST1_17652178_ChIP-ChIP_JURKAT_Human4.45962029
4E2F7_22180533_ChIP-Seq_HELA_Human4.29834785
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.55711960
6CREB1_15753290_ChIP-ChIP_HEK293T_Human3.50857556
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.49528150
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.43934452
9ELF1_17652178_ChIP-ChIP_JURKAT_Human3.18433995
10MYC_18555785_ChIP-Seq_MESCs_Mouse3.14474345
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.13533391
12ETS1_20019798_ChIP-Seq_JURKAT_Human3.09530784
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.09349601
14VDR_23849224_ChIP-Seq_CD4+_Human2.96109936
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.95941810
16NOTCH1_21737748_ChIP-Seq_TLL_Human2.93246655
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.92110286
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.89687472
19ELK1_19687146_ChIP-ChIP_HELA_Human2.76041180
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.59562865
21FOXP3_21729870_ChIP-Seq_TREG_Human2.59248631
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.56914354
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.46780915
24PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.14427505
25MYC_19030024_ChIP-ChIP_MESCs_Mouse2.07558741
26MYC_18358816_ChIP-ChIP_MESCs_Mouse2.02489255
27MYC_19079543_ChIP-ChIP_MESCs_Mouse1.98612518
28FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.95039684
29HOXB4_20404135_ChIP-ChIP_EML_Mouse1.88648302
30TTF2_22483619_ChIP-Seq_HELA_Human1.87423510
31DCP1A_22483619_ChIP-Seq_HELA_Human1.79655057
32* XRN2_22483619_ChIP-Seq_HELA_Human1.74202203
33GABP_19822575_ChIP-Seq_HepG2_Human1.73464503
34MYC_18940864_ChIP-ChIP_HL60_Human1.73098930
35FOXM1_23109430_ChIP-Seq_U2OS_Human1.72050287
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71322397
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.70961923
38* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.70241794
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.64781447
40NELFA_20434984_ChIP-Seq_ESCs_Mouse1.63075237
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.62696517
42ZNF274_21170338_ChIP-Seq_K562_Hela1.61304467
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.58692665
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.58182858
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.55914897
46IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.54034129
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52276455
48CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.51273695
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.50133730
50E2F1_18555785_ChIP-Seq_MESCs_Mouse1.48605286
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.45426917
52EWS_26573619_Chip-Seq_HEK293_Human1.31405023
53SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30160499
54MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.30001492
55TP63_19390658_ChIP-ChIP_HaCaT_Human1.28563423
56CIITA_25753668_ChIP-Seq_RAJI_Human1.24079048
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.23095020
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22673193
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18947465
60IRF1_19129219_ChIP-ChIP_H3396_Human1.17548817
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.17412455
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15071636
63MYCN_18555785_ChIP-Seq_MESCs_Mouse1.14827380
64CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14297664
65VDR_22108803_ChIP-Seq_LS180_Human1.13345629
66KDM5A_27292631_Chip-Seq_BREAST_Human1.12911235
67SOX2_16153702_ChIP-ChIP_HESCs_Human1.09915877
68MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.08087406
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.06657804
70IRF8_21731497_ChIP-ChIP_J774_Mouse1.02952965
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02873507
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01986923
73SPI1_23547873_ChIP-Seq_NB4_Human1.01305462
74POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96161501
75KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.93413415
76FUS_26573619_Chip-Seq_HEK293_Human0.91816952
77TP53_22573176_ChIP-Seq_HFKS_Human0.90710189
78ELK1_22589737_ChIP-Seq_MCF10A_Human0.89516637
79POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89272833
80* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89271143
81BP1_19119308_ChIP-ChIP_Hs578T_Human0.88180710
82CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.87619353
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.87580440
84ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.87436937
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.87221389
86BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.87219161
87E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.82398645
88SALL4_22934838_ChIP-ChIP_CD34+_Human0.82371063
89SOX2_18555785_ChIP-Seq_MESCs_Mouse0.80495707
90CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.79389798
91KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.77361693
92KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.77361693
93KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.77361693
94CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.76426053
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75020605
96MYB_26560356_Chip-Seq_TH2_Human0.74458000
97TFEB_21752829_ChIP-Seq_HELA_Human0.72927175
98PCGF2_27294783_Chip-Seq_ESCs_Mouse0.71247596
99GATA3_26560356_Chip-Seq_TH1_Human0.68691626
100HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.68643926

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair4.12519030
2MP0003693_abnormal_embryo_hatching3.30583776
3MP0010094_abnormal_chromosome_stability3.15730144
4MP0008877_abnormal_DNA_methylation3.06239772
5MP0005671_abnormal_response_to2.88429300
6MP0002102_abnormal_ear_morphology2.74517761
7MP0008057_abnormal_DNA_replication2.68765797
8MP0003111_abnormal_nucleus_morphology2.64806637
9MP0004957_abnormal_blastocyst_morpholog2.34963329
10MP0003077_abnormal_cell_cycle2.32597374
11MP0000372_irregular_coat_pigmentation2.08337204
12MP0003718_maternal_effect2.07438736
13MP0003186_abnormal_redox_activity1.99807835
14MP0003786_premature_aging1.92453675
15MP0002638_abnormal_pupillary_reflex1.85454053
16MP0002277_abnormal_respiratory_mucosa1.83432276
17MP0006082_CNS_inflammation1.78260482
18MP0009333_abnormal_splenocyte_physiolog1.75833184
19MP0006292_abnormal_olfactory_placode1.74081970
20MP0001835_abnormal_antigen_presentation1.68599615
21MP0000569_abnormal_digit_pigmentation1.66930520
22MP0006036_abnormal_mitochondrial_physio1.65745684
23MP0008007_abnormal_cellular_replicative1.56397269
24MP0009785_altered_susceptibility_to1.52369693
25MP0002132_abnormal_respiratory_system1.51941957
26MP0008932_abnormal_embryonic_tissue1.50717921
27MP0003880_abnormal_central_pattern1.49049928
28MP0001800_abnormal_humoral_immune1.48393643
29MP0006072_abnormal_retinal_apoptosis1.42716394
30MP0005084_abnormal_gallbladder_morpholo1.40081377
31MP0003136_yellow_coat_color1.37873510
32MP0001529_abnormal_vocalization1.35729906
33MP0002452_abnormal_antigen_presenting1.32053656
34MP0008789_abnormal_olfactory_epithelium1.31546807
35MP0006035_abnormal_mitochondrial_morpho1.31318019
36MP0001485_abnormal_pinna_reflex1.30598107
37MP0002420_abnormal_adaptive_immunity1.29884858
38MP0002148_abnormal_hypersensitivity_rea1.29672515
39MP0002723_abnormal_immune_serum1.29446902
40MP0003656_abnormal_erythrocyte_physiolo1.29440330
41MP0001819_abnormal_immune_cell1.28141456
42MP0005000_abnormal_immune_tolerance1.25417668
43MP0002398_abnormal_bone_marrow1.25404034
44MP0001853_heart_inflammation1.23743580
45MP0001293_anophthalmia1.22902859
46MP0002234_abnormal_pharynx_morphology1.20841403
47MP0000689_abnormal_spleen_morphology1.20510571
48MP0005075_abnormal_melanosome_morpholog1.19919768
49MP0008995_early_reproductive_senescence1.19880955
50MP0001764_abnormal_homeostasis1.19577878
51MP0004742_abnormal_vestibular_system1.18460930
52MP0005499_abnormal_olfactory_system1.18196411
53MP0005394_taste/olfaction_phenotype1.18196411
54MP0003878_abnormal_ear_physiology1.16506624
55MP0005377_hearing/vestibular/ear_phenot1.16506624
56MP0002722_abnormal_immune_system1.15191735
57MP0002396_abnormal_hematopoietic_system1.14909580
58MP0002210_abnormal_sex_determination1.14542607
59MP0002095_abnormal_skin_pigmentation1.13849526
60MP0000703_abnormal_thymus_morphology1.10988303
61MP0000716_abnormal_immune_system1.10431451
62MP0004142_abnormal_muscle_tone1.09909236
63MP0002160_abnormal_reproductive_system1.07250669
64MP0000313_abnormal_cell_death1.05843931
65MP0002736_abnormal_nociception_after1.05801116
66MP0003806_abnormal_nucleotide_metabolis1.05512171
67MP0001929_abnormal_gametogenesis1.03002532
68MP0003763_abnormal_thymus_physiology1.02987582
69MP0005387_immune_system_phenotype1.02699919
70MP0001790_abnormal_immune_system1.02699919
71MP0009379_abnormal_foot_pigmentation1.01477844
72MP0005253_abnormal_eye_physiology1.01354182
73MP0005025_abnormal_response_to1.00087532
74MP0009765_abnormal_xenobiotic_induced0.96872762
75MP0000350_abnormal_cell_proliferation0.96044855
76MP0002419_abnormal_innate_immunity0.93211479
77MP0002429_abnormal_blood_cell0.92283033
78MP0001119_abnormal_female_reproductive0.91781024
79MP0003303_peritoneal_inflammation0.90667171
80MP0003315_abnormal_perineum_morphology0.90008187
81MP0002405_respiratory_system_inflammati0.89988652
82MP0003221_abnormal_cardiomyocyte_apopto0.85332770
83MP0005389_reproductive_system_phenotype0.85271041
84MP0001145_abnormal_male_reproductive0.84208994
85MP0000631_abnormal_neuroendocrine_gland0.83642072
86MP0002019_abnormal_tumor_incidence0.83610373
87MP0000516_abnormal_urinary_system0.83147629
88MP0005367_renal/urinary_system_phenotyp0.83147629
89MP0001727_abnormal_embryo_implantation0.83110338
90MP0009764_decreased_sensitivity_to0.83076530
91MP0002006_tumorigenesis0.81561711
92MP0005174_abnormal_tail_pigmentation0.81369651
93MP0000653_abnormal_sex_gland0.81089455
94MP0003567_abnormal_fetal_cardiomyocyte0.79178556
95MP0001984_abnormal_olfaction0.78825373
96MP0002938_white_spotting0.78519082
97MP0001905_abnormal_dopamine_level0.77370950
98MP0008873_increased_physiological_sensi0.72101672
99MP0002166_altered_tumor_susceptibility0.71510483
100MP0003195_calcinosis0.70309778

Predicted human phenotypes

RankGene SetZ-score
1Decreased activity of mitochondrial respiratory chain (HP:0008972)3.99905993
2Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.99905993
33-Methylglutaconic aciduria (HP:0003535)3.86239950
4Acute necrotizing encephalopathy (HP:0006965)3.78274283
5Abnormal mitochondria in muscle tissue (HP:0008316)3.52344721
6Progressive macrocephaly (HP:0004481)3.39362443
7Abnormal number of erythroid precursors (HP:0012131)3.37890144
8Mitochondrial inheritance (HP:0001427)3.30837661
9Acute encephalopathy (HP:0006846)3.29666843
10Abnormality of cells of the erythroid lineage (HP:0012130)3.19672206
11Stomatitis (HP:0010280)3.13896695
12Macrocytic anemia (HP:0001972)3.04664676
13Increased CSF lactate (HP:0002490)3.00948347
14Increased hepatocellular lipid droplets (HP:0006565)2.92624567
15Hepatocellular necrosis (HP:0001404)2.66266997
16Reticulocytopenia (HP:0001896)2.62106789
17Lipid accumulation in hepatocytes (HP:0006561)2.61621667
18Pallor (HP:0000980)2.60576265
19Methylmalonic acidemia (HP:0002912)2.59108246
20Abnormal delayed hypersensitivity skin test (HP:0002963)2.54855214
21Aplastic anemia (HP:0001915)2.52942699
22Increased intramyocellular lipid droplets (HP:0012240)2.47218905
23Agnosia (HP:0010524)2.42654603
24Cerebral edema (HP:0002181)2.42095357
25Hepatic necrosis (HP:0002605)2.38298610
26Abnormality of T cell physiology (HP:0011840)2.37566499
27Methylmalonic aciduria (HP:0012120)2.36543992
28Renal Fanconi syndrome (HP:0001994)2.34943852
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.32977453
30Exertional dyspnea (HP:0002875)2.31418062
31Abnormality of the anterior horn cell (HP:0006802)2.31110963
32Degeneration of anterior horn cells (HP:0002398)2.31110963
33Abnormal hemoglobin (HP:0011902)2.30726362
34Abnormality of chromosome stability (HP:0003220)2.25546836
35Encephalitis (HP:0002383)2.23915123
36Colon cancer (HP:0003003)2.23356438
37Lactic acidosis (HP:0003128)2.22372323
38Increased IgM level (HP:0003496)2.21680220
39IgM deficiency (HP:0002850)2.20194625
40Pancytopenia (HP:0001876)2.17086560
41Increased serum lactate (HP:0002151)2.16544105
42Abnormality of T cells (HP:0002843)2.16289489
43Neutropenia (HP:0001875)2.12946291
44Birth length less than 3rd percentile (HP:0003561)2.10103271
45Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.07637525
46Panhypogammaglobulinemia (HP:0003139)2.05188010
47Meckel diverticulum (HP:0002245)2.04301292
48Oral leukoplakia (HP:0002745)2.02438727
49Chromsome breakage (HP:0040012)2.01664121
50Constricted visual fields (HP:0001133)1.99959757
51Abnormality of the preputium (HP:0100587)1.99816569
52Abnormality of the labia minora (HP:0012880)1.99560501
53Stenosis of the external auditory canal (HP:0000402)1.99452556
54Respiratory difficulties (HP:0002880)1.96095943
55Hypoplastic pelvis (HP:0008839)1.95111337
56Aplasia/Hypoplasia of the sacrum (HP:0008517)1.94908839
57Abnormality of B cell number (HP:0010975)1.94858910
58Abnormality of the ileum (HP:0001549)1.93135216
59IgG deficiency (HP:0004315)1.92828518
60Aplasia/Hypoplasia of the uvula (HP:0010293)1.91785190
61Increased muscle lipid content (HP:0009058)1.91665560
62Optic disc pallor (HP:0000543)1.91359252
63Cellular immunodeficiency (HP:0005374)1.90660451
64Absent rod-and cone-mediated responses on ERG (HP:0007688)1.88223354
65Hypothermia (HP:0002045)1.87369647
66Exercise intolerance (HP:0003546)1.86925053
67Abnormal lung lobation (HP:0002101)1.84186936
68Elevated erythrocyte sedimentation rate (HP:0003565)1.83373163
69Stomach cancer (HP:0012126)1.83167214
70Respiratory failure (HP:0002878)1.82878686
71Abnormality of T cell number (HP:0011839)1.82310965
72Horseshoe kidney (HP:0000085)1.82042140
73Short tibia (HP:0005736)1.80840708
74Abnormality of the heme biosynthetic pathway (HP:0010472)1.80293710
75Chromosomal breakage induced by crosslinking agents (HP:0003221)1.79007155
76Hyperglycinemia (HP:0002154)1.78998207
77Dyschromatopsia (HP:0007641)1.77263409
78Abolished electroretinogram (ERG) (HP:0000550)1.76815215
79Absent thumb (HP:0009777)1.76361948
80Pendular nystagmus (HP:0012043)1.75670829
81Triphalangeal thumb (HP:0001199)1.75393123
82Limb hypertonia (HP:0002509)1.74364786
83Abnormal rod and cone electroretinograms (HP:0008323)1.73393929
84Abnormality of renal resorption (HP:0011038)1.72969099
85Aplasia/hypoplasia of the uterus (HP:0008684)1.72827936
86B lymphocytopenia (HP:0010976)1.72790674
87Autoimmune hemolytic anemia (HP:0001890)1.72662604
88Congenital stationary night blindness (HP:0007642)1.72616678
89Chronic otitis media (HP:0000389)1.69636768
90Oligodactyly (hands) (HP:0001180)1.69148029
91True hermaphroditism (HP:0010459)1.68811965
92Medial flaring of the eyebrow (HP:0010747)1.68343080
93Atrophy/Degeneration involving motor neurons (HP:0007373)1.67652866
94Disinhibition (HP:0000734)1.65903127
95Eosinophilia (HP:0001880)1.65354083
96Pancreatic cysts (HP:0001737)1.62762067
97Cleft eyelid (HP:0000625)1.61362420
98Clubbing of toes (HP:0100760)1.61268892
99Agammaglobulinemia (HP:0004432)1.61099094
100Recurrent bacterial skin infections (HP:0005406)1.60879905

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.39882834
2CDC73.36693664
3STK163.33013991
4SRPK13.01723268
5TRIM282.60810501
6VRK22.60763079
7CDK192.47417239
8EIF2AK12.47123745
9MST42.33976088
10VRK12.17142308
11TSSK62.08846331
12NUAK11.78213116
13TLK11.70620317
14WNK31.69896680
15TXK1.66759783
16TAOK31.59192963
17NEK11.57987443
18EIF2AK31.53243676
19TNIK1.52241596
20PASK1.50981461
21MKNK21.49803642
22MKNK11.47348273
23GRK71.45285898
24PLK41.44577118
25MAP3K121.38682173
26IRAK41.36532065
27WEE11.29711898
28DYRK31.29340812
29TTK1.28591826
30PNCK1.24715508
31CLK11.21177575
32PBK1.20501358
33STK101.20028449
34MARK31.15939727
35ERBB31.14179552
36PLK31.13005190
37CDK31.12901072
38TAOK11.11846141
39ZAK1.09532944
40CASK1.01498338
41RPS6KA41.01226026
42BRSK21.00960863
43TNK20.98582428
44NME10.97784034
45PLK10.96863311
46RPS6KA50.95522175
47NME20.94572051
48MAP4K10.92962673
49BCKDK0.92172298
50TESK20.90549549
51PIM10.90286189
52ATR0.89106885
53TAF10.87208180
54AURKB0.86829797
55MAP3K40.82063282
56TEC0.81438981
57ITK0.80048224
58AURKA0.77836441
59DYRK20.76221456
60MATK0.74955128
61ADRBK20.74941743
62CHEK20.71350908
63IKBKE0.71248621
64PIM20.69655641
65TGFBR20.67631407
66CSNK2A20.67448984
67TAOK20.66684477
68IKBKB0.63144557
69CSNK2A10.62292714
70CHEK10.60665854
71ATM0.58238170
72PDK20.57752395
73BMPR1B0.57363634
74EIF2AK20.56384106
75LYN0.53733290
76MAP4K20.53710912
77CSK0.53230094
78FGR0.52330729
79CSNK1G30.50469538
80RAF10.49245489
81MOS0.48996260
82MAP3K50.48672855
83BCR0.48429684
84CSNK1G10.46741951
85BTK0.43943773
86INSRR0.43514631
87MAP2K70.43233966
88PRKCG0.42975726
89GRK10.42456116
90GRK50.42285801
91BRD40.42258531
92IRAK10.41752183
93CSNK1G20.41137979
94SYK0.38516714
95CSNK1A1L0.38022110
96PRKCQ0.37286091
97CCNB10.35357825
98RIPK40.33981982
99OXSR10.33522992
100YES10.32850817

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.74633489
2Proteasome_Homo sapiens_hsa030503.41423216
3Oxidative phosphorylation_Homo sapiens_hsa001903.23565088
4RNA polymerase_Homo sapiens_hsa030202.96311501
5Parkinsons disease_Homo sapiens_hsa050122.88677512
6DNA replication_Homo sapiens_hsa030302.87922551
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.87814857
8Mismatch repair_Homo sapiens_hsa034302.83479070
9Spliceosome_Homo sapiens_hsa030402.77843653
10Protein export_Homo sapiens_hsa030602.51542452
11Homologous recombination_Homo sapiens_hsa034402.43369569
12Basal transcription factors_Homo sapiens_hsa030222.34772532
13Base excision repair_Homo sapiens_hsa034102.27183591
14Nucleotide excision repair_Homo sapiens_hsa034202.25200653
15Huntingtons disease_Homo sapiens_hsa050162.08885773
16RNA degradation_Homo sapiens_hsa030182.03771115
17RNA transport_Homo sapiens_hsa030132.03101545
18Primary immunodeficiency_Homo sapiens_hsa053402.01200847
19Non-homologous end-joining_Homo sapiens_hsa034501.96877650
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.89574622
21Fanconi anemia pathway_Homo sapiens_hsa034601.86613892
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.72994510
23Pyrimidine metabolism_Homo sapiens_hsa002401.68344717
24Alzheimers disease_Homo sapiens_hsa050101.61978641
25Graft-versus-host disease_Homo sapiens_hsa053321.55270331
26Allograft rejection_Homo sapiens_hsa053301.32817966
27Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.29191815
28Cell cycle_Homo sapiens_hsa041101.27369654
29One carbon pool by folate_Homo sapiens_hsa006701.25734755
30Autoimmune thyroid disease_Homo sapiens_hsa053201.19396078
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.19168210
32Type I diabetes mellitus_Homo sapiens_hsa049401.13845335
33mRNA surveillance pathway_Homo sapiens_hsa030151.10401916
34Purine metabolism_Homo sapiens_hsa002301.09798877
35Propanoate metabolism_Homo sapiens_hsa006401.06967235
36Antigen processing and presentation_Homo sapiens_hsa046121.05156474
37Intestinal immune network for IgA production_Homo sapiens_hsa046720.99000314
38Legionellosis_Homo sapiens_hsa051340.98862287
39Epstein-Barr virus infection_Homo sapiens_hsa051690.94627962
40Phototransduction_Homo sapiens_hsa047440.93637409
41Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.87990948
42Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.87116227
43Regulation of autophagy_Homo sapiens_hsa041400.85483614
44Herpes simplex infection_Homo sapiens_hsa051680.85226494
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84931877
46Folate biosynthesis_Homo sapiens_hsa007900.84042763
47Systemic lupus erythematosus_Homo sapiens_hsa053220.78772623
48RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.76961765
49Rheumatoid arthritis_Homo sapiens_hsa053230.76637768
50NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74105833
51Asthma_Homo sapiens_hsa053100.73879023
52Measles_Homo sapiens_hsa051620.71658448
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.70686193
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70391539
55p53 signaling pathway_Homo sapiens_hsa041150.68487492
56Cardiac muscle contraction_Homo sapiens_hsa042600.64331859
57Collecting duct acid secretion_Homo sapiens_hsa049660.63186946
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61180792
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60690771
60NF-kappa B signaling pathway_Homo sapiens_hsa040640.60227967
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54806538
62Fatty acid elongation_Homo sapiens_hsa000620.52873857
63Steroid biosynthesis_Homo sapiens_hsa001000.52424966
64Oocyte meiosis_Homo sapiens_hsa041140.51867491
65Hematopoietic cell lineage_Homo sapiens_hsa046400.51634910
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51150957
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50963710
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.49798050
69Leishmaniasis_Homo sapiens_hsa051400.46682167
70Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46204402
71Sulfur relay system_Homo sapiens_hsa041220.45823398
72Viral myocarditis_Homo sapiens_hsa054160.44513870
73Peroxisome_Homo sapiens_hsa041460.43178373
74Selenocompound metabolism_Homo sapiens_hsa004500.42958951
75Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42063035
76Vitamin digestion and absorption_Homo sapiens_hsa049770.40989698
77Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40802497
78Pyruvate metabolism_Homo sapiens_hsa006200.40151583
79Metabolic pathways_Homo sapiens_hsa011000.39473437
80Viral carcinogenesis_Homo sapiens_hsa052030.38079690
81Caffeine metabolism_Homo sapiens_hsa002320.37957219
82Nitrogen metabolism_Homo sapiens_hsa009100.36837753
83Hepatitis B_Homo sapiens_hsa051610.35173904
84Malaria_Homo sapiens_hsa051440.35169970
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34038380
86Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.34031900
87Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.33356179
88Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33333258
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32917324
90T cell receptor signaling pathway_Homo sapiens_hsa046600.32422581
91Influenza A_Homo sapiens_hsa051640.32319067
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.31128596
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.28950650
94Glutathione metabolism_Homo sapiens_hsa004800.28902207
95African trypanosomiasis_Homo sapiens_hsa051430.28856674
96Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26970677
97Mineral absorption_Homo sapiens_hsa049780.26356073
98Apoptosis_Homo sapiens_hsa042100.26276690
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.25769388
100Tuberculosis_Homo sapiens_hsa051520.25694425

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »