ZNF793

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.92726132
2fucose catabolic process (GO:0019317)4.57033123
3L-fucose metabolic process (GO:0042354)4.57033123
4L-fucose catabolic process (GO:0042355)4.57033123
5response to pheromone (GO:0019236)4.37152988
6indole-containing compound catabolic process (GO:0042436)3.95877155
7indolalkylamine catabolic process (GO:0046218)3.95877155
8tryptophan catabolic process (GO:0006569)3.95877155
9kynurenine metabolic process (GO:0070189)3.93569819
10indolalkylamine metabolic process (GO:0006586)3.69995447
11gamma-aminobutyric acid transport (GO:0015812)3.63490844
12detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.49035344
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.45985877
14tryptophan metabolic process (GO:0006568)3.36823763
15negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.36411723
16negative regulation of translation, ncRNA-mediated (GO:0040033)3.36411723
17regulation of translation, ncRNA-mediated (GO:0045974)3.36411723
18kidney morphogenesis (GO:0060993)3.28658408
19cellular ketone body metabolic process (GO:0046950)3.28059677
20pyrimidine nucleobase catabolic process (GO:0006208)3.25836416
21negative regulation of telomere maintenance (GO:0032205)3.21315860
22neural tube formation (GO:0001841)3.15257851
23nonmotile primary cilium assembly (GO:0035058)3.11050541
24neuronal action potential (GO:0019228)3.10615680
25detection of light stimulus involved in sensory perception (GO:0050962)3.10149961
26detection of light stimulus involved in visual perception (GO:0050908)3.10149961
27DNA deamination (GO:0045006)3.08244424
28behavioral response to ethanol (GO:0048149)3.07850152
29indole-containing compound metabolic process (GO:0042430)3.03775568
30epithelial cilium movement (GO:0003351)3.00486070
31negative regulation of synaptic transmission, GABAergic (GO:0032229)2.99681799
32sulfation (GO:0051923)2.96820666
33G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.95889947
34ketone body metabolic process (GO:1902224)2.93492192
35regulation of action potential (GO:0098900)2.90119701
36primary amino compound metabolic process (GO:1901160)2.88307078
37reflex (GO:0060004)2.88168821
38regulation of nuclear cell cycle DNA replication (GO:0033262)2.88162375
39nucleobase catabolic process (GO:0046113)2.82737366
40transmission of nerve impulse (GO:0019226)2.79571452
41postsynaptic membrane organization (GO:0001941)2.79518349
42mitochondrial respiratory chain complex I assembly (GO:0032981)2.79101663
43NADH dehydrogenase complex assembly (GO:0010257)2.79101663
44mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.79101663
45protein polyglutamylation (GO:0018095)2.78067457
46somite development (GO:0061053)2.77324101
47water-soluble vitamin biosynthetic process (GO:0042364)2.77246335
48membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.75568615
49presynaptic membrane assembly (GO:0097105)2.73592434
50cornea development in camera-type eye (GO:0061303)2.72509365
51regulation of posttranscriptional gene silencing (GO:0060147)2.72405367
52regulation of gene silencing by miRNA (GO:0060964)2.72405367
53regulation of gene silencing by RNA (GO:0060966)2.72405367
54serotonin metabolic process (GO:0042428)2.71888825
55cilium morphogenesis (GO:0060271)2.70119554
56spinal cord motor neuron differentiation (GO:0021522)2.69352312
57protein complex biogenesis (GO:0070271)2.69336298
58protein localization to cilium (GO:0061512)2.68741404
59synaptic transmission, cholinergic (GO:0007271)2.68216176
60startle response (GO:0001964)2.68211882
61cAMP catabolic process (GO:0006198)2.67617332
62axoneme assembly (GO:0035082)2.66870932
63cilium organization (GO:0044782)2.65610325
64regulation of hippo signaling (GO:0035330)2.63257136
65regulation of telomere maintenance (GO:0032204)2.62731207
66negative regulation of cytosolic calcium ion concentration (GO:0051481)2.62077635
67nephron epithelium morphogenesis (GO:0072088)2.61329669
68nephron tubule morphogenesis (GO:0072078)2.61329669
69retinal cone cell development (GO:0046549)2.60502858
70piRNA metabolic process (GO:0034587)2.60407342
71cilium assembly (GO:0042384)2.59018895
72cilium or flagellum-dependent cell motility (GO:0001539)2.58569555
73cilium movement (GO:0003341)2.58483175
74replication fork processing (GO:0031297)2.57831113
75reciprocal meiotic recombination (GO:0007131)2.57016102
76reciprocal DNA recombination (GO:0035825)2.57016102
77cellular biogenic amine catabolic process (GO:0042402)2.56980072
78amine catabolic process (GO:0009310)2.56980072
79negative regulation of DNA-dependent DNA replication (GO:2000104)2.56169138
80platelet dense granule organization (GO:0060155)2.55392605
81regulation of mesoderm development (GO:2000380)2.55003300
82negative regulation of mast cell activation (GO:0033004)2.54664070
83membrane depolarization during action potential (GO:0086010)2.53318124
84negative regulation of transcription regulatory region DNA binding (GO:2000678)2.52740881
85protein-cofactor linkage (GO:0018065)2.50583458
86regulation of rhodopsin mediated signaling pathway (GO:0022400)2.50377433
87neuron cell-cell adhesion (GO:0007158)2.50369739
88mitochondrial respiratory chain complex assembly (GO:0033108)2.49484944
89regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.49225310
90presynaptic membrane organization (GO:0097090)2.48395157
91fucosylation (GO:0036065)2.47341786
92head development (GO:0060322)2.46788977
93positive regulation of oligodendrocyte differentiation (GO:0048714)2.45916355
94limb bud formation (GO:0060174)2.45404289
95positive regulation of action potential (GO:0045760)2.44707204
96respiratory chain complex IV assembly (GO:0008535)2.44588373
97rRNA catabolic process (GO:0016075)2.44315105
98NAD biosynthetic process (GO:0009435)2.43300649
99rhodopsin mediated signaling pathway (GO:0016056)2.42905627
100cyclic nucleotide catabolic process (GO:0009214)2.39900013

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.90978736
2EZH2_22144423_ChIP-Seq_EOC_Human3.88046430
3GBX2_23144817_ChIP-Seq_PC3_Human3.30498802
4VDR_22108803_ChIP-Seq_LS180_Human3.20979626
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.16278456
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.67145007
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.65972440
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.30947004
9CTBP1_25329375_ChIP-Seq_LNCAP_Human2.22718657
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.17459938
11TAF15_26573619_Chip-Seq_HEK293_Human2.14209154
12FUS_26573619_Chip-Seq_HEK293_Human2.12680620
13IGF1R_20145208_ChIP-Seq_DFB_Human2.11072660
14EWS_26573619_Chip-Seq_HEK293_Human2.09872912
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.02089210
16P300_19829295_ChIP-Seq_ESCs_Human2.00554801
17SALL1_21062744_ChIP-ChIP_HESCs_Human1.98883336
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.88322898
19ER_23166858_ChIP-Seq_MCF-7_Human1.81615954
20SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70477151
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.69834891
22CBX2_27304074_Chip-Seq_ESCs_Mouse1.69095272
23HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67414082
24REST_21632747_ChIP-Seq_MESCs_Mouse1.67407349
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67115732
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.65831271
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.63503769
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62924437
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61696732
30STAT3_23295773_ChIP-Seq_U87_Human1.61162339
31HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60982180
32POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.60156773
33TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60156773
34PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60145371
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.59155719
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.58310998
37BCAT_22108803_ChIP-Seq_LS180_Human1.57569365
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56360333
39UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56331418
40IRF1_19129219_ChIP-ChIP_H3396_Human1.52888971
41MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.52666941
42SMAD4_21799915_ChIP-Seq_A2780_Human1.51292204
43NR3C1_21868756_ChIP-Seq_MCF10A_Human1.49809482
44CBP_20019798_ChIP-Seq_JUKART_Human1.48353484
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48353484
46AR_25329375_ChIP-Seq_VCAP_Human1.47652066
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.46956728
48* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45971634
49* TCF4_23295773_ChIP-Seq_U87_Human1.44384715
50AR_21572438_ChIP-Seq_LNCaP_Human1.41237513
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.40636020
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39540324
53RNF2_27304074_Chip-Seq_NSC_Mouse1.37292697
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35860567
55TP53_22573176_ChIP-Seq_HFKS_Human1.35544542
56EZH2_27304074_Chip-Seq_ESCs_Mouse1.31900077
57PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31106510
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.28693613
59JARID2_20064375_ChIP-Seq_MESCs_Mouse1.27731069
60TCF4_22108803_ChIP-Seq_LS180_Human1.26267606
61RUNX2_22187159_ChIP-Seq_PCA_Human1.24959376
62MYC_18940864_ChIP-ChIP_HL60_Human1.23282782
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.22821963
64SOX2_19829295_ChIP-Seq_ESCs_Human1.21476733
65NANOG_19829295_ChIP-Seq_ESCs_Human1.21476733
66DROSHA_22980978_ChIP-Seq_HELA_Human1.18997653
67GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17923170
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.17701667
69FOXA1_25329375_ChIP-Seq_VCAP_Human1.16721922
70FOXA1_27270436_Chip-Seq_PROSTATE_Human1.16721922
71EED_16625203_ChIP-ChIP_MESCs_Mouse1.15878584
72SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15307853
73* SMAD4_21741376_ChIP-Seq_EPCs_Human1.15114485
74OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13852382
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12501569
76PRDM14_20953172_ChIP-Seq_ESCs_Human1.11736443
77* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11691632
78FLI1_21867929_ChIP-Seq_TH2_Mouse1.10745913
79* ETV2_25802403_ChIP-Seq_MESCs_Mouse1.09953961
80TP53_16413492_ChIP-PET_HCT116_Human1.09719713
81SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.08531973
82EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.08369492
83GATA3_21878914_ChIP-Seq_MCF-7_Human1.07844127
84NFE2_27457419_Chip-Seq_LIVER_Mouse1.07605523
85EZH2_27294783_Chip-Seq_ESCs_Mouse1.07290085
86TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05175974
87REST_18959480_ChIP-ChIP_MESCs_Mouse1.04765166
88FOXA1_21572438_ChIP-Seq_LNCaP_Human1.04483396
89EZH2_27294783_Chip-Seq_NPCs_Mouse1.02568391
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.02411557
91NCOR_22424771_ChIP-Seq_293T_Human1.01620832
92POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01432590
93JARID2_20075857_ChIP-Seq_MESCs_Mouse1.01160064
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99585760
95TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98997581
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98681889
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98409620
98SOX2_21211035_ChIP-Seq_LN229_Gbm0.98369266
99HOXB7_26014856_ChIP-Seq_BT474_Human0.97880012
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.96638771

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002102_abnormal_ear_morphology2.67808809
2MP0008877_abnormal_DNA_methylation2.64297674
3MP0003195_calcinosis2.62742068
4MP0000569_abnormal_digit_pigmentation2.49288972
5MP0001968_abnormal_touch/_nociception2.43362721
6MP0005551_abnormal_eye_electrophysiolog2.25021776
7MP0003787_abnormal_imprinting2.22408627
8MP0009745_abnormal_behavioral_response2.21902558
9MP0009046_muscle_twitch2.16633909
10MP0006292_abnormal_olfactory_placode2.05634241
11MP0002736_abnormal_nociception_after2.04101488
12MP0003136_yellow_coat_color2.01299361
13MP0003646_muscle_fatigue1.98389912
14MP0004885_abnormal_endolymph1.97205958
15MP0002653_abnormal_ependyma_morphology1.93328175
16MP0004142_abnormal_muscle_tone1.90246803
17MP0001501_abnormal_sleep_pattern1.86912826
18MP0004043_abnormal_pH_regulation1.86744748
19MP0002272_abnormal_nervous_system1.82960005
20MP0004133_heterotaxia1.81075749
21MP0005646_abnormal_pituitary_gland1.79616242
22MP0006072_abnormal_retinal_apoptosis1.77177681
23MP0003880_abnormal_central_pattern1.76595833
24MP0001986_abnormal_taste_sensitivity1.75605189
25MP0002837_dystrophic_cardiac_calcinosis1.71850921
26MP0001485_abnormal_pinna_reflex1.71200168
27MP0008872_abnormal_physiological_respon1.71172711
28MP0002064_seizures1.66182299
29MP0001486_abnormal_startle_reflex1.65940844
30MP0000631_abnormal_neuroendocrine_gland1.65466800
31MP0000427_abnormal_hair_cycle1.64754310
32MP0002735_abnormal_chemical_nociception1.64476272
33MP0005645_abnormal_hypothalamus_physiol1.62237616
34MP0008875_abnormal_xenobiotic_pharmacok1.61939002
35MP0002638_abnormal_pupillary_reflex1.61193235
36MP0006276_abnormal_autonomic_nervous1.59343798
37MP0002572_abnormal_emotion/affect_behav1.57172552
38MP0005253_abnormal_eye_physiology1.57159983
39MP0002938_white_spotting1.56510385
40MP0004742_abnormal_vestibular_system1.54192578
41MP0002876_abnormal_thyroid_physiology1.53506761
42MP0003635_abnormal_synaptic_transmissio1.49386984
43MP0003283_abnormal_digestive_organ1.46015732
44MP0002557_abnormal_social/conspecific_i1.45889028
45MP0002063_abnormal_learning/memory/cond1.40715293
46MP0000778_abnormal_nervous_system1.39208195
47MP0002234_abnormal_pharynx_morphology1.34887444
48MP0002067_abnormal_sensory_capabilities1.32531509
49MP0005386_behavior/neurological_phenoty1.30132213
50MP0004924_abnormal_behavior1.30132213
51MP0001984_abnormal_olfaction1.29852393
52MP0002733_abnormal_thermal_nociception1.29634166
53MP0001970_abnormal_pain_threshold1.29394073
54MP0004145_abnormal_muscle_electrophysio1.28266030
55MP0005174_abnormal_tail_pigmentation1.27455769
56MP0003890_abnormal_embryonic-extraembry1.24107555
57MP0004147_increased_porphyrin_level1.20480875
58MP0000383_abnormal_hair_follicle1.19886504
59MP0003121_genomic_imprinting1.19507439
60MP0003011_delayed_dark_adaptation1.17248269
61MP0002734_abnormal_mechanical_nocicepti1.15616685
62MP0003878_abnormal_ear_physiology1.10536252
63MP0005377_hearing/vestibular/ear_phenot1.10536252
64MP0001529_abnormal_vocalization1.09136690
65MP0005423_abnormal_somatic_nervous1.06719457
66MP0005195_abnormal_posterior_eye1.06389763
67MP0003119_abnormal_digestive_system1.06273599
68MP0002928_abnormal_bile_duct1.05707366
69MP0000026_abnormal_inner_ear1.03714228
70MP0002752_abnormal_somatic_nervous1.02182671
71MP0005389_reproductive_system_phenotype1.01809516
72MP0010386_abnormal_urinary_bladder1.01568038
73MP0003122_maternal_imprinting1.01517211
74MP0002184_abnormal_innervation1.01266487
75MP0002751_abnormal_autonomic_nervous1.00865228
76MP0002160_abnormal_reproductive_system1.00322809
77MP0001293_anophthalmia0.98437368
78MP0004215_abnormal_myocardial_fiber0.97024143
79MP0003718_maternal_effect0.96755197
80MP0000372_irregular_coat_pigmentation0.94624992
81MP0003937_abnormal_limbs/digits/tail_de0.93805681
82MP0001919_abnormal_reproductive_system0.93263186
83MP0000955_abnormal_spinal_cord0.92678674
84MP0005084_abnormal_gallbladder_morpholo0.90085107
85MP0003137_abnormal_impulse_conducting0.88850940
86MP0002882_abnormal_neuron_morphology0.87510711
87MP0001963_abnormal_hearing_physiology0.87338657
88MP0001905_abnormal_dopamine_level0.84396094
89MP0002095_abnormal_skin_pigmentation0.83824516
90MP0008995_early_reproductive_senescence0.83818812
91MP0000647_abnormal_sebaceous_gland0.83428678
92MP0001502_abnormal_circadian_rhythm0.82838462
93MP0002229_neurodegeneration0.81974823
94MP0003698_abnormal_male_reproductive0.81893561
95MP0000049_abnormal_middle_ear0.81863493
96MP0008961_abnormal_basal_metabolism0.81658697
97MP0005187_abnormal_penis_morphology0.81079044
98MP0000538_abnormal_urinary_bladder0.79884909
99MP0000230_abnormal_systemic_arterial0.78719525
100MP0001324_abnormal_eye_pigmentation0.77891797

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.76095193
2Abnormality of midbrain morphology (HP:0002418)4.31639094
3Molar tooth sign on MRI (HP:0002419)4.31639094
4Pancreatic fibrosis (HP:0100732)4.30220294
5True hermaphroditism (HP:0010459)4.26660751
6Nephronophthisis (HP:0000090)3.82555162
7Congenital stationary night blindness (HP:0007642)3.77706476
8Hyperventilation (HP:0002883)3.46247501
9Abnormality of the renal medulla (HP:0100957)3.30925460
10Abnormality of the renal cortex (HP:0011035)3.07581607
11Cystic liver disease (HP:0006706)3.06831562
12Progressive cerebellar ataxia (HP:0002073)3.06814739
13Attenuation of retinal blood vessels (HP:0007843)2.93126172
14Type II lissencephaly (HP:0007260)2.92138072
15Genetic anticipation (HP:0003743)2.91215068
16Chronic hepatic failure (HP:0100626)2.89585874
17Medial flaring of the eyebrow (HP:0010747)2.85703494
18Inability to walk (HP:0002540)2.84817795
19Abnormality of alanine metabolism (HP:0010916)2.72529084
20Hyperalaninemia (HP:0003348)2.72529084
21Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.72529084
22Tubular atrophy (HP:0000092)2.71016737
23Protruding tongue (HP:0010808)2.70609842
24Gaze-evoked nystagmus (HP:0000640)2.64876855
25Sclerocornea (HP:0000647)2.62782982
26Pendular nystagmus (HP:0012043)2.60111619
27Abolished electroretinogram (ERG) (HP:0000550)2.54515104
28Progressive inability to walk (HP:0002505)2.52645520
29Broad-based gait (HP:0002136)2.51174353
30Furrowed tongue (HP:0000221)2.47407374
31Anencephaly (HP:0002323)2.41612417
32Lissencephaly (HP:0001339)2.39064263
33Concave nail (HP:0001598)2.38219101
34Gait imbalance (HP:0002141)2.37556867
35Polydipsia (HP:0001959)2.36901557
36Abnormal drinking behavior (HP:0030082)2.36901557
37Patellar aplasia (HP:0006443)2.36676555
38Large for gestational age (HP:0001520)2.35452551
39Aplasia/Hypoplasia of the tongue (HP:0010295)2.32109589
40Decreased central vision (HP:0007663)2.28117076
41Febrile seizures (HP:0002373)2.27301925
42Increased corneal curvature (HP:0100692)2.26464149
43Keratoconus (HP:0000563)2.26464149
44Birth length less than 3rd percentile (HP:0003561)2.23057216
45Congenital primary aphakia (HP:0007707)2.21837197
46Aplasia/Hypoplasia of the patella (HP:0006498)2.21046856
47Congenital, generalized hypertrichosis (HP:0004540)2.20652640
48Congenital hepatic fibrosis (HP:0002612)2.18172675
49Clumsiness (HP:0002312)2.15967925
50Male pseudohermaphroditism (HP:0000037)2.15203149
51Abnormal biliary tract physiology (HP:0012439)2.15153999
52Bile duct proliferation (HP:0001408)2.15153999
53Abnormal rod and cone electroretinograms (HP:0008323)2.14372190
54Absent/shortened dynein arms (HP:0200106)2.14343664
55Dynein arm defect of respiratory motile cilia (HP:0012255)2.14343664
56Cerebellar dysplasia (HP:0007033)2.14063371
57Decreased circulating renin level (HP:0003351)2.12628245
58Stomach cancer (HP:0012126)2.11722796
59Abnormality of the labia minora (HP:0012880)2.11251563
60Aplasia/Hypoplasia of the tibia (HP:0005772)2.09681466
61Genital tract atresia (HP:0001827)2.09631616
62Chorioretinal atrophy (HP:0000533)2.09236136
63Nephrogenic diabetes insipidus (HP:0009806)2.06889911
64Vaginal atresia (HP:0000148)2.04871902
65Optic nerve hypoplasia (HP:0000609)2.02327661
66Postaxial foot polydactyly (HP:0001830)2.01632660
67Focal motor seizures (HP:0011153)2.01623734
68Polyuria (HP:0000103)2.00035550
69Renal cortical cysts (HP:0000803)1.99911257
70Hemiparesis (HP:0001269)1.99134627
71Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97611681
72Absent speech (HP:0001344)1.97141641
73Colon cancer (HP:0003003)1.97040483
74Focal seizures (HP:0007359)1.91687924
75Abnormality of the pons (HP:0007361)1.91580081
76Hypoplasia of the pons (HP:0012110)1.89923099
77Pachygyria (HP:0001302)1.88300055
78Decreased electroretinogram (ERG) amplitude (HP:0000654)1.86302669
79Bony spicule pigmentary retinopathy (HP:0007737)1.86079988
80Fair hair (HP:0002286)1.84608593
81Abnormal respiratory motile cilium morphology (HP:0005938)1.83667934
82Abnormal respiratory epithelium morphology (HP:0012253)1.83667934
83Oligodactyly (hands) (HP:0001180)1.82201615
84Bilateral microphthalmos (HP:0007633)1.81413741
85Severe muscular hypotonia (HP:0006829)1.78755148
86Anophthalmia (HP:0000528)1.77312846
87Poor coordination (HP:0002370)1.76713560
88Tachypnea (HP:0002789)1.75731888
89Dialeptic seizures (HP:0011146)1.74741907
90Preaxial hand polydactyly (HP:0001177)1.73885609
91Absent rod-and cone-mediated responses on ERG (HP:0007688)1.72536979
92Optic disc pallor (HP:0000543)1.72383808
93Partial agenesis of the corpus callosum (HP:0001338)1.72288622
94Postaxial hand polydactyly (HP:0001162)1.71784652
95Congenital sensorineural hearing impairment (HP:0008527)1.71764475
96Limb dystonia (HP:0002451)1.71081703
97Retinal dysplasia (HP:0007973)1.71034215
98Dandy-Walker malformation (HP:0001305)1.69383368
99Abnormal ciliary motility (HP:0012262)1.68355034
100Drooling (HP:0002307)1.68230625

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.97570623
2ADRBK23.34164239
3BMPR1B3.31747286
4WNK32.80991033
5ACVR1B2.71179121
6CASK2.59086798
7INSRR2.55037852
8WNK42.42323466
9ZAK2.35378560
10GRK12.30094239
11PINK12.28843901
12MAP4K22.25743053
13TLK12.21518749
14NUAK11.97999444
15MAPK131.97677909
16MARK11.91251147
17TNIK1.85581609
18TAOK31.81018550
19MAP3K41.69468941
20OXSR11.56727236
21MKNK21.55874565
22PNCK1.49488010
23DAPK21.49280229
24STK391.36661500
25NTRK31.30544049
26ADRBK11.26251963
27DYRK21.25818385
28TGFBR11.21958829
29PAK31.11961035
30NTRK21.10674269
31PRKCG1.04284227
32TXK1.03569744
33FGFR21.00942447
34MAP2K70.98212171
35MAPK150.94376010
36PRKCE0.92637821
37PIK3CA0.92087978
38EPHA40.88162140
39SIK20.86094626
40STK38L0.80179449
41CSNK1G20.78084552
42MAP2K60.75907216
43PLK20.75329191
44PHKG20.73321413
45PHKG10.73321413
46CAMKK20.73268435
47MKNK10.71050147
48CAMK1D0.69468339
49AKT30.67607472
50CSNK1G10.67076928
51VRK10.67057474
52NLK0.66938573
53TIE10.66385922
54MAPKAPK30.64973928
55CAMK1G0.61690093
56PKN10.61434371
57CAMK2A0.59928532
58PTK2B0.59602186
59CSNK1G30.59272675
60NEK20.58433964
61CSNK1A1L0.58303353
62BCR0.57672680
63TRIM280.57248023
64STK110.57039185
65MAPKAPK50.56980435
66CAMK10.56805268
67WEE10.50419545
68OBSCN0.50062357
69RPS6KA50.49743250
70PRKACA0.45871748
71MUSK0.45633754
72TEC0.45598474
73PRKCQ0.45233920
74PLK40.44669954
75BCKDK0.44176093
76BRSK20.42884623
77SGK20.42558586
78KIT0.42207600
79PRKCZ0.42034668
80CHUK0.41756949
81CSNK1D0.41690918
82DYRK1A0.40205501
83CSNK1A10.39516570
84WNK10.38286854
85PRKAA10.37891396
86ERBB20.37725976
87TYRO30.36426264
88NME10.35345486
89SGK2230.34381641
90SGK4940.34381641
91PRKCA0.34025507
92CDK30.33878457
93PLK30.33572090
94GRK70.33500959
95PRKG10.33319641
96TAF10.33087317
97IRAK10.32827077
98CHEK20.32794500
99MAP2K40.32322117
100RPS6KA60.32064246

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.93233805
2Nicotine addiction_Homo sapiens_hsa050332.89462419
3Linoleic acid metabolism_Homo sapiens_hsa005912.68301497
4Nitrogen metabolism_Homo sapiens_hsa009102.62074997
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.58477072
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.54475626
7Butanoate metabolism_Homo sapiens_hsa006502.36988152
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.23449560
9Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.20722904
10Selenocompound metabolism_Homo sapiens_hsa004502.10352258
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.10122337
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.97073548
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.85252485
14Tryptophan metabolism_Homo sapiens_hsa003801.82352864
15Ether lipid metabolism_Homo sapiens_hsa005651.80177721
16Homologous recombination_Homo sapiens_hsa034401.79919213
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.77662973
18Caffeine metabolism_Homo sapiens_hsa002321.75046090
19Oxidative phosphorylation_Homo sapiens_hsa001901.73849743
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.72412485
21Morphine addiction_Homo sapiens_hsa050321.71947349
22Taste transduction_Homo sapiens_hsa047421.71254769
23Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.53634657
24Fanconi anemia pathway_Homo sapiens_hsa034601.51195174
25RNA polymerase_Homo sapiens_hsa030201.49807216
26Olfactory transduction_Homo sapiens_hsa047401.49739369
27Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48635961
28Basal transcription factors_Homo sapiens_hsa030221.44601259
29Circadian entrainment_Homo sapiens_hsa047131.41088814
30Glutamatergic synapse_Homo sapiens_hsa047241.37456253
31GABAergic synapse_Homo sapiens_hsa047271.32879847
32Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.32118970
33Parkinsons disease_Homo sapiens_hsa050121.29952440
34Insulin secretion_Homo sapiens_hsa049111.25924063
35Cardiac muscle contraction_Homo sapiens_hsa042601.22693494
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.22297721
37ABC transporters_Homo sapiens_hsa020101.21957429
38Serotonergic synapse_Homo sapiens_hsa047261.21219981
39Protein export_Homo sapiens_hsa030601.20270429
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.16815166
41Propanoate metabolism_Homo sapiens_hsa006401.14939825
42Steroid hormone biosynthesis_Homo sapiens_hsa001401.07407613
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.06427786
44Intestinal immune network for IgA production_Homo sapiens_hsa046721.04133244
45Chemical carcinogenesis_Homo sapiens_hsa052041.03331653
46RNA degradation_Homo sapiens_hsa030180.99387504
47Calcium signaling pathway_Homo sapiens_hsa040200.97506505
48One carbon pool by folate_Homo sapiens_hsa006700.96602091
49Peroxisome_Homo sapiens_hsa041460.96234422
50Ovarian steroidogenesis_Homo sapiens_hsa049130.92206795
51Huntingtons disease_Homo sapiens_hsa050160.91930178
52Arachidonic acid metabolism_Homo sapiens_hsa005900.91676681
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90819897
54Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.89869388
55Salivary secretion_Homo sapiens_hsa049700.87290941
56Alzheimers disease_Homo sapiens_hsa050100.86310899
57Retinol metabolism_Homo sapiens_hsa008300.83683234
58Dopaminergic synapse_Homo sapiens_hsa047280.82724020
59Cocaine addiction_Homo sapiens_hsa050300.80242387
60Glycerolipid metabolism_Homo sapiens_hsa005610.76276109
61Histidine metabolism_Homo sapiens_hsa003400.76156605
62Regulation of autophagy_Homo sapiens_hsa041400.75978786
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74005288
64beta-Alanine metabolism_Homo sapiens_hsa004100.73226265
65Cholinergic synapse_Homo sapiens_hsa047250.70699524
66Hedgehog signaling pathway_Homo sapiens_hsa043400.70426667
67Long-term depression_Homo sapiens_hsa047300.69775282
68Amphetamine addiction_Homo sapiens_hsa050310.67635514
69Dorso-ventral axis formation_Homo sapiens_hsa043200.67633029
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67534216
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66518088
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65390679
73Basal cell carcinoma_Homo sapiens_hsa052170.65162495
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.64368524
75Purine metabolism_Homo sapiens_hsa002300.59539245
76cAMP signaling pathway_Homo sapiens_hsa040240.54818002
77Gastric acid secretion_Homo sapiens_hsa049710.53951802
78Fat digestion and absorption_Homo sapiens_hsa049750.52262932
79Collecting duct acid secretion_Homo sapiens_hsa049660.51735417
80Circadian rhythm_Homo sapiens_hsa047100.49892787
81Oxytocin signaling pathway_Homo sapiens_hsa049210.48940112
82Mineral absorption_Homo sapiens_hsa049780.47383941
83Asthma_Homo sapiens_hsa053100.46996004
84Metabolic pathways_Homo sapiens_hsa011000.43952875
85Sulfur relay system_Homo sapiens_hsa041220.42592870
86Axon guidance_Homo sapiens_hsa043600.41258119
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41153237
88Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39132879
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.39102335
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37759475
91Aldosterone synthesis and secretion_Homo sapiens_hsa049250.37306953
92Vitamin digestion and absorption_Homo sapiens_hsa049770.36472578
93Renin secretion_Homo sapiens_hsa049240.35793372
94Primary immunodeficiency_Homo sapiens_hsa053400.35790167
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.35209047
96Fatty acid biosynthesis_Homo sapiens_hsa000610.33956486
97Non-homologous end-joining_Homo sapiens_hsa034500.32562801
98Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31744841
99Lysine degradation_Homo sapiens_hsa003100.31306333
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30945094

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