ZNF792

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.44385682
2positive regulation of gamma-delta T cell activation (GO:0046645)5.28107558
3regulation of B cell receptor signaling pathway (GO:0050855)5.14653392
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.31392848
5T cell migration (GO:0072678)4.28106907
6dendritic cell chemotaxis (GO:0002407)4.27096990
7negative regulation of erythrocyte differentiation (GO:0045647)4.13426889
8B cell receptor signaling pathway (GO:0050853)4.02053151
9positive regulation of B cell differentiation (GO:0045579)4.00404143
10tolerance induction (GO:0002507)3.94856806
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.92471343
12negative regulation of cell killing (GO:0031342)3.92471343
13megakaryocyte development (GO:0035855)3.87299901
14neutrophil activation involved in immune response (GO:0002283)3.85433818
15dendritic cell migration (GO:0036336)3.75429943
16definitive hemopoiesis (GO:0060216)3.72697481
17negative thymic T cell selection (GO:0045060)3.70671062
18positive regulation of granulocyte differentiation (GO:0030854)3.69464113
19negative T cell selection (GO:0043383)3.67938309
20positive regulation of endothelial cell differentiation (GO:0045603)3.67519729
21positive regulation of interleukin-2 production (GO:0032743)3.65751818
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.63056112
23regulation of gamma-delta T cell differentiation (GO:0045586)3.62701579
24thrombin receptor signaling pathway (GO:0070493)3.61142737
25positive T cell selection (GO:0043368)3.55589331
26response to muramyl dipeptide (GO:0032495)3.54457350
27regulation of B cell differentiation (GO:0045577)3.50262887
28antigen processing and presentation of endogenous antigen (GO:0019883)3.49125042
29endothelium development (GO:0003158)3.49102684
30B cell homeostasis (GO:0001782)3.48920293
31positive regulation of alpha-beta T cell proliferation (GO:0046641)3.47468460
32response to interleukin-15 (GO:0070672)3.43491366
33positive regulation of T cell cytokine production (GO:0002726)3.41299379
34cellular extravasation (GO:0045123)3.40856912
35endothelial tube morphogenesis (GO:0061154)3.36436167
36morphogenesis of an endothelium (GO:0003159)3.36436167
37regulation of gamma-delta T cell activation (GO:0046643)3.32607647
38regulation of alpha-beta T cell proliferation (GO:0046640)3.31383192
39positive thymic T cell selection (GO:0045059)3.27489946
40regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.25789469
41phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.22455844
42positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.18070946
433-UTR-mediated mRNA stabilization (GO:0070935)3.17456584
44positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.16419315
45antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.13369635
46T cell selection (GO:0045058)3.12969178
47neutrophil activation (GO:0042119)3.11795578
48dosage compensation (GO:0007549)3.10785406
49negative regulation of thymocyte apoptotic process (GO:0070244)3.06974198
50negative regulation of glycoprotein biosynthetic process (GO:0010561)3.04325097
51blood vessel maturation (GO:0001955)3.03008192
52regulation of myeloid leukocyte mediated immunity (GO:0002886)3.01420132
53thymic T cell selection (GO:0045061)3.01026641
54negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.98711717
55positive regulation of T cell differentiation in thymus (GO:0033089)2.95902330
56hepatocyte apoptotic process (GO:0097284)2.95548832
57regulation of leukocyte degranulation (GO:0043300)2.95493424
58antigen receptor-mediated signaling pathway (GO:0050851)2.94875118
59lipid translocation (GO:0034204)2.93038290
60phospholipid translocation (GO:0045332)2.93038290
61ribosome assembly (GO:0042255)2.92275210
62embryonic hemopoiesis (GO:0035162)2.87941722
63interkinetic nuclear migration (GO:0022027)2.83661721
64transcription from mitochondrial promoter (GO:0006390)2.83458389
65histone lysine demethylation (GO:0070076)2.83449058
66embryonic process involved in female pregnancy (GO:0060136)2.78767270
67negative regulation of DNA repair (GO:0045738)2.77941158
68lymphocyte homeostasis (GO:0002260)2.74313386
69T cell receptor signaling pathway (GO:0050852)2.71615786
70negative regulation of T cell apoptotic process (GO:0070233)2.71025880
71regulation of interleukin-2 production (GO:0032663)2.69567656
72detection of other organism (GO:0098543)2.69287908
73histone demethylation (GO:0016577)2.68202485
74negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.66958387
75detection of bacterium (GO:0016045)2.63709852
76cellular response to interleukin-15 (GO:0071350)2.61231055
77regulation of mast cell degranulation (GO:0043304)2.60668263
78granulocyte activation (GO:0036230)2.60317172
79histone mRNA catabolic process (GO:0071044)2.60005380
80nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)2.59855513
81regulation of erythrocyte differentiation (GO:0045646)2.59157833
82mast cell activation (GO:0045576)2.58139945
83platelet formation (GO:0030220)2.57671741
84regulation of endothelial cell differentiation (GO:0045601)2.57169602
85peptidyl-threonine dephosphorylation (GO:0035970)2.56969766
86T cell proliferation (GO:0042098)2.56148797
87erythrocyte maturation (GO:0043249)2.55540981
88negative regulation of leukocyte mediated immunity (GO:0002704)2.55410391
89regulation of fibroblast apoptotic process (GO:2000269)2.53154904
90regulation of regulatory T cell differentiation (GO:0045589)2.52882468
91positive regulation of alpha-beta T cell activation (GO:0046635)2.50639327
92T cell homeostasis (GO:0043029)2.49623412
93protein dealkylation (GO:0008214)2.49369543
94protein demethylation (GO:0006482)2.49369543
95positive regulation of interleukin-17 production (GO:0032740)2.48641951
96cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.47800206
97response to peptidoglycan (GO:0032494)2.47633829
98leukocyte aggregation (GO:0070486)2.47478785
99interferon-gamma production (GO:0032609)2.47360491
100antigen processing and presentation via MHC class Ib (GO:0002475)2.46890803

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.29809094
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.33800182
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.10418063
4SCL_19346495_ChIP-Seq_HPC-7_Human4.09952477
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.56617195
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.54713102
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.35429865
8RUNX_20019798_ChIP-Seq_JUKART_Human3.19297346
9MYC_22102868_ChIP-Seq_BL_Human3.01283674
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.86725563
11MYB_26560356_Chip-Seq_TH2_Human2.83227502
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.79295690
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.77741991
14GATA1_22025678_ChIP-Seq_K562_Human2.74110148
15SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.58080301
16FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.56157373
17MYB_21317192_ChIP-Seq_ERMYB_Mouse2.53448491
18STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.52282045
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.51823629
20MYB_26560356_Chip-Seq_TH1_Human2.48233086
21SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.30494916
22* GATA2_21666600_ChIP-Seq_HMVEC_Human2.29105818
23MAF_26560356_Chip-Seq_TH1_Human2.26279589
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.23293299
25RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.20464996
26ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.19522133
27SPI1_23127762_ChIP-Seq_K562_Human2.15175354
28SPI1_23547873_ChIP-Seq_NB4_Human2.13793201
29VDR_21846776_ChIP-Seq_THP-1_Human2.08985976
30TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse2.06347546
31VDR_24763502_ChIP-Seq_THP-1_Human2.04581471
32UTX_26944678_Chip-Seq_JUKART_Human2.01936910
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.01682244
34TCF7_22412390_ChIP-Seq_EML_Mouse1.92863243
35STAT4_19710469_ChIP-ChIP_TH1__Mouse1.87746720
36STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.87738683
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.85151684
38IRF8_27001747_Chip-Seq_BMDM_Mouse1.83934520
39Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.82986409
40* GATA3_27048872_Chip-Seq_THYMUS_Human1.82665622
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.79732284
42SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.77393728
43GATA1_19941826_ChIP-Seq_K562_Human1.75690529
44BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.73350984
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.72294843
46* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.72192601
47* GATA2_19941826_ChIP-Seq_K562_Human1.71026827
48KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.67029396
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.66109482
50MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.62956638
51GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.62057953
52IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.59018616
53CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.57671936
54ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57276842
55RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.57167581
56BRD4_27068464_Chip-Seq_AML-cells_Mouse1.57019796
57E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.55291999
58GATA2_22383799_ChIP-Seq_G1ME_Mouse1.50741805
59MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.49539440
60CIITA_25753668_ChIP-Seq_RAJI_Human1.48240486
61MAF_26560356_Chip-Seq_TH2_Human1.48240310
62GATA1_19941827_ChIP-Seq_MEL_Mouse1.47980333
63NCOR1_26117541_ChIP-Seq_K562_Human1.44098409
64KDM2B_26808549_Chip-Seq_SUP-B15_Human1.41003200
65SMAD_19615063_ChIP-ChIP_OVARY_Human1.39530367
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.37644395
67* KDM2B_26808549_Chip-Seq_JURKAT_Human1.37419349
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34993622
69ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33997793
70VDR_24787735_ChIP-Seq_THP-1_Human1.32988221
71IRF8_21731497_ChIP-ChIP_J774_Mouse1.30853759
72* GATA3_26560356_Chip-Seq_TH2_Human1.30827362
73KDM2B_26808549_Chip-Seq_DND41_Human1.27418415
74FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.26465275
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.25804200
76E2F7_22180533_ChIP-Seq_HELA_Human1.24902827
77LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.24788559
78LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.23544447
79HOXB4_20404135_ChIP-ChIP_EML_Mouse1.20278576
80E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19900685
81STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19746162
82ELK3_25401928_ChIP-Seq_HUVEC_Human1.11345411
83PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06209221
84RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05486224
85TP63_19390658_ChIP-ChIP_HaCaT_Human1.05288885
86PU_27001747_Chip-Seq_BMDM_Mouse1.02731180
87KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.02393157
88KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.02393157
89KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.02393157
90ETS1_22383799_ChIP-Seq_G1ME_Mouse1.00140847
91NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.99183533
92NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92378142
93GATA3_26560356_Chip-Seq_TH1_Human0.92145410
94SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.91287747
95GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.89784925
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88917038
97FOXO3_23340844_ChIP-Seq_DLD1_Human0.88310743
98* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88258729
99PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86176169
100GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83898029

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000465_gastrointestinal_hemorrhage3.95397737
2MP0003724_increased_susceptibility_to3.44251286
3MP0005464_abnormal_platelet_physiology3.40817950
4MP0003763_abnormal_thymus_physiology3.19424716
5MP0003436_decreased_susceptibility_to3.08522067
6MP0001835_abnormal_antigen_presentation2.94041295
7MP0003828_pulmonary_edema2.60440599
8MP0008057_abnormal_DNA_replication2.50979846
9MP0003300_gastrointestinal_ulcer2.47279614
10MP0010368_abnormal_lymphatic_system2.47219098
11MP0002009_preneoplasia2.42019945
12MP0002396_abnormal_hematopoietic_system2.34753357
13MP0001800_abnormal_humoral_immune2.29391500
14MP0002398_abnormal_bone_marrow2.24221665
15MP0005000_abnormal_immune_tolerance2.18138070
16MP0003303_peritoneal_inflammation2.12321087
17MP0001879_abnormal_lymphatic_vessel2.04658649
18MP0009697_abnormal_copulation2.03504637
19MP0009333_abnormal_splenocyte_physiolog1.97823423
20MP0000703_abnormal_thymus_morphology1.97562830
21MP0002723_abnormal_immune_serum1.95016178
22MP0002420_abnormal_adaptive_immunity1.94001959
23MP0001819_abnormal_immune_cell1.92763696
24MP0002166_altered_tumor_susceptibility1.91720745
25MP0002452_abnormal_antigen_presenting1.88691800
26MP0002419_abnormal_innate_immunity1.85496626
27MP0000689_abnormal_spleen_morphology1.83823779
28MP0005167_abnormal_blood-brain_barrier1.81417447
29MP0010155_abnormal_intestine_physiology1.80935031
30MP0002722_abnormal_immune_system1.80653577
31MP0000716_abnormal_immune_system1.73490887
32MP0004808_abnormal_hematopoietic_stem1.70433162
33MP0005025_abnormal_response_to1.66804294
34MP0005671_abnormal_response_to1.64346216
35MP0003866_abnormal_defecation1.58690098
36MP0002429_abnormal_blood_cell1.57045196
37MP0008004_abnormal_stomach_pH1.47963406
38MP0005397_hematopoietic_system_phenotyp1.45251624
39MP0001545_abnormal_hematopoietic_system1.45251624
40MP0001790_abnormal_immune_system1.39008640
41MP0005387_immune_system_phenotype1.39008640
42MP0003567_abnormal_fetal_cardiomyocyte1.37555381
43MP0001851_eye_inflammation1.36105949
44MP0009278_abnormal_bone_marrow1.35945011
45MP0002148_abnormal_hypersensitivity_rea1.30773431
46MP0003191_abnormal_cellular_cholesterol1.27932761
47MP0000685_abnormal_immune_system1.24852259
48MP0002127_abnormal_cardiovascular_syste1.22554049
49MP0008007_abnormal_cellular_replicative1.21741331
50MP0002006_tumorigenesis1.21634212
51MP0002405_respiratory_system_inflammati1.18339641
52MP0005076_abnormal_cell_differentiation1.15503796
53MP0004084_abnormal_cardiac_muscle1.13714024
54MP0001845_abnormal_inflammatory_respons1.12490696
55MP0001533_abnormal_skeleton_physiology1.12235038
56MP0002086_abnormal_extraembryonic_tissu1.10831613
57MP0003566_abnormal_cell_adhesion1.08719593
58MP0003943_abnormal_hepatobiliary_system1.08516799
59MP0001730_embryonic_growth_arrest1.08285842
60MP0004947_skin_inflammation1.07105790
61MP0001915_intracranial_hemorrhage1.06754308
62MP0003091_abnormal_cell_migration1.06393655
63MP0003984_embryonic_growth_retardation1.04394204
64MP0004264_abnormal_extraembryonic_tissu1.03980094
65MP0002088_abnormal_embryonic_growth/wei1.02944301
66MP0009785_altered_susceptibility_to1.00567671
67MP0005310_abnormal_salivary_gland1.00092711
68MP0001986_abnormal_taste_sensitivity0.99592366
69MP0003656_abnormal_erythrocyte_physiolo0.99314828
70MP0002019_abnormal_tumor_incidence0.98754125
71MP0008260_abnormal_autophagy0.98358569
72MP0010352_gastrointestinal_tract_polyps0.96172147
73MP0002925_abnormal_cardiovascular_devel0.94207104
74MP0009764_decreased_sensitivity_to0.94127481
75MP0000249_abnormal_blood_vessel0.94085519
76MP0002933_joint_inflammation0.93634503
77MP0005621_abnormal_cell_physiology0.92186533
78MP0002128_abnormal_blood_circulation0.91899466
79MP0003221_abnormal_cardiomyocyte_apopto0.90976498
80MP0001672_abnormal_embryogenesis/_devel0.87871230
81MP0005380_embryogenesis_phenotype0.87871230
82MP0004883_abnormal_blood_vessel0.87456198
83MP0002998_abnormal_bone_remodeling0.87305361
84MP0003690_abnormal_glial_cell0.87039462
85MP0003172_abnormal_lysosome_physiology0.82341881
86MP0000858_altered_metastatic_potential0.81767857
87MP0000604_amyloidosis0.80791120
88MP0000350_abnormal_cell_proliferation0.80415289
89MP0008961_abnormal_basal_metabolism0.79083478
90MP0001784_abnormal_fluid_regulation0.78933243
91MP0000598_abnormal_liver_morphology0.76835051
92MP0005451_abnormal_body_composition0.76119535
93MP0004130_abnormal_muscle_cell0.75293924
94MP0010630_abnormal_cardiac_muscle0.73146096
95MP0002132_abnormal_respiratory_system0.70266691
96MP0000490_abnormal_crypts_of0.69750937
97MP0004185_abnormal_adipocyte_glucose0.68985168
98MP0000313_abnormal_cell_death0.66996381
99MP0005165_increased_susceptibility_to0.66282232
100MP0008469_abnormal_protein_level0.65924939

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)4.84770765
2Spontaneous hematomas (HP:0007420)4.15507201
3Elevated erythrocyte sedimentation rate (HP:0003565)4.14632713
4Abnormal platelet volume (HP:0011876)4.07270568
5Increased mean platelet volume (HP:0011877)3.96232550
6Abnormality of the fingertips (HP:0001211)3.93760888
7Epistaxis (HP:0000421)3.92598419
8Panhypogammaglobulinemia (HP:0003139)3.92190189
9Menorrhagia (HP:0000132)3.83230669
10Abnormal delayed hypersensitivity skin test (HP:0002963)3.61296650
11Colitis (HP:0002583)3.33978166
12Viral hepatitis (HP:0006562)3.30604304
13Gingival bleeding (HP:0000225)3.28388716
14Recurrent viral infections (HP:0004429)3.18183045
15Eczematoid dermatitis (HP:0000976)3.08957701
16Stomach cancer (HP:0012126)3.08193791
17Abnormality of T cell number (HP:0011839)3.06106227
18T lymphocytopenia (HP:0005403)3.05343342
19Pulmonary infiltrates (HP:0002113)3.00782614
20Increased IgM level (HP:0003496)2.95619370
21Inflammation of the large intestine (HP:0002037)2.84178154
22Tubulointerstitial nephritis (HP:0001970)2.79888272
23Gastrointestinal inflammation (HP:0004386)2.78507705
24Autoimmune hemolytic anemia (HP:0001890)2.76770852
25Mediastinal lymphadenopathy (HP:0100721)2.76476215
26Abnormality of T cells (HP:0002843)2.73774406
27Subacute progressive viral hepatitis (HP:0006572)2.70687992
28Impaired platelet aggregation (HP:0003540)2.70186086
29Abnormal platelet function (HP:0011869)2.70186086
30Septate vagina (HP:0001153)2.68611041
31Myositis (HP:0100614)2.64427759
32Papillary thyroid carcinoma (HP:0002895)2.63109273
33Skull defect (HP:0001362)2.62670421
34Stomatitis (HP:0010280)2.56394129
35IgM deficiency (HP:0002850)2.54731075
36Cellulitis (HP:0100658)2.54195540
37Acute myeloid leukemia (HP:0004808)2.52661256
38Acute lymphatic leukemia (HP:0006721)2.51793899
39Recurrent fungal infections (HP:0002841)2.49965706
40Granulocytopenia (HP:0001913)2.47040504
41Abnormality of T cell physiology (HP:0011840)2.44005889
42Hypertensive crisis (HP:0100735)2.43657086
43Intestinal fistula (HP:0100819)2.42493343
44Pustule (HP:0200039)2.41435398
45Clumsiness (HP:0002312)2.40903860
46Recurrent abscess formation (HP:0002722)2.39333626
47Agammaglobulinemia (HP:0004432)2.38276182
48Abnormality of the columella (HP:0009929)2.36146898
49Rectovaginal fistula (HP:0000143)2.28957578
50Rectal fistula (HP:0100590)2.28957578
51Renal cortical cysts (HP:0000803)2.27589411
52Thrombocytosis (HP:0001894)2.26690240
53Mucosal telangiectasiae (HP:0100579)2.25901632
54Acanthocytosis (HP:0001927)2.25401930
55Microcytic anemia (HP:0001935)2.25070120
56Encephalitis (HP:0002383)2.24162670
57Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.23329780
58Petechiae (HP:0000967)2.22400931
59Eosinophilia (HP:0001880)2.21960818
60Autoimmune thrombocytopenia (HP:0001973)2.20917950
61Recurrent bacterial skin infections (HP:0005406)2.19348738
62Cutis marmorata (HP:0000965)2.18869595
63Supernumerary ribs (HP:0005815)2.18797219
64Fair hair (HP:0002286)2.18267835
65Protruding tongue (HP:0010808)2.17505249
66Gastrointestinal infarctions (HP:0005244)2.14697844
67Chest pain (HP:0100749)2.14416510
68Hyperlipoproteinemia (HP:0010980)2.13836707
69Chronic obstructive pulmonary disease (HP:0006510)2.10164662
70Obstructive lung disease (HP:0006536)2.10164662
71Esophageal varix (HP:0002040)2.09979203
72Polycythemia (HP:0001901)2.07470497
73Abnormal hemoglobin (HP:0011902)2.06824376
74Abnormal hair whorl (HP:0010721)2.06241643
75Xerostomia (HP:0000217)2.05795711
76Meningitis (HP:0001287)2.05674971
77IgG deficiency (HP:0004315)2.05472495
78Leukocytosis (HP:0001974)2.04821798
79Supernumerary bones of the axial skeleton (HP:0009144)2.01303098
80Abnormality of B cell number (HP:0010975)1.98143157
81Hematochezia (HP:0002573)1.97529833
82Abnormality of eosinophils (HP:0001879)1.97370511
83Recurrent cutaneous fungal infections (HP:0011370)1.96836716
84Chronic mucocutaneous candidiasis (HP:0002728)1.96836716
85Purpura (HP:0000979)1.95528115
86Vaginal fistula (HP:0004320)1.91565957
87Abnormality of the prostate (HP:0008775)1.90861649
88Teleangiectasia of the skin (HP:0100585)1.90459683
89Ankyloglossia (HP:0010296)1.89887772
90Conjunctival telangiectasia (HP:0000524)1.89555948
91Spinal cord lesions (HP:0100561)1.88663102
92Syringomyelia (HP:0003396)1.88663102
93Hepatitis (HP:0012115)1.88034086
94Papilloma (HP:0012740)1.86988880
95Verrucae (HP:0200043)1.86988880
96Prominent nose (HP:0000448)1.80544225
97Poikilocytosis (HP:0004447)1.79780261
98Clubbing of toes (HP:0100760)1.78681827
99Arterial thrombosis (HP:0004420)1.78613834
100Vasculitis (HP:0002633)1.77934659

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK34.84904606
2FES3.77923979
3MAP4K13.17577922
4TIE13.11735936
5RIPK43.08404643
6GRK62.44017932
7MAP3K142.21326942
8BTK2.16180783
9TEC2.10061309
10KDR2.08371784
11MAP2K31.85480614
12TXK1.84870882
13SYK1.72211538
14HCK1.65721793
15CAMKK21.58302544
16PRPF4B1.55168209
17ZAP701.54538667
18IKBKE1.51887995
19PIM11.51877676
20EEF2K1.50331444
21ITK1.47498895
22STK41.46280710
23GRK51.42494688
24PKN21.40065559
25CDK121.36408827
26JAK31.28259137
27TRIM281.28214675
28SCYL21.26948749
29BLK1.25731984
30MAP3K101.24145139
31TBK11.21654068
32NLK1.19650772
33LYN1.17406438
34IRAK21.17202267
35IKBKB1.16519738
36BMPR21.16122478
37LCK1.12338164
38FGFR31.11297496
39CSK1.10211742
40MAP2K21.09754800
41FLT31.08073501
42TGFBR21.07862818
43STK101.04812030
44EPHB11.02168269
45JAK20.99706195
46MARK20.99447836
47IRAK40.99268831
48CLK10.99025273
49JAK10.96349021
50NUAK10.95914772
51BRD40.93753097
52RPS6KB20.89091880
53PIK3CG0.87687972
54LRRK20.86453586
55RAF10.85155635
56MAP3K70.79701893
57CCNB10.79661781
58PTK2B0.78274399
59FGFR40.77829325
60BMX0.77296253
61RET0.75992682
62RPS6KL10.72805759
63RPS6KC10.72805759
64CDK40.72779887
65DAPK10.71708325
66MAPK110.71508024
67CDK60.71459526
68PDK10.68957113
69BRSK20.68189122
70MAPK70.67767255
71CSF1R0.66918641
72SGK20.64616102
73TYK20.64476360
74RPS6KA60.63093717
75EPHA30.61709835
76HIPK20.60440369
77TRIB30.58734882
78PRKCQ0.57349803
79YES10.56882241
80TNK20.56675320
81RPS6KA20.56453812
82MAP3K130.53888399
83PASK0.53625486
84MAPK120.49866815
85PRKAA20.46076175
86STK30.45293882
87CAMK1D0.45099707
88CHUK0.44940800
89MAP3K110.44805101
90FGR0.43654969
91MAP3K10.43591421
92MAPKAPK20.41552519
93TRPM70.41192720
94CAMKK10.41061054
95SGK30.40720952
96CDC70.37953249
97MARK30.37794160
98IRAK10.36559900
99FER0.35679313
100WNK10.35377844

Predicted pathways (KEGG)

RankGene SetZ-score
1Acute myeloid leukemia_Homo sapiens_hsa052212.86011320
2B cell receptor signaling pathway_Homo sapiens_hsa046622.60650695
3T cell receptor signaling pathway_Homo sapiens_hsa046602.26296962
4Platelet activation_Homo sapiens_hsa046112.25351258
5RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.15272289
6Non-small cell lung cancer_Homo sapiens_hsa052232.12681685
7Chronic myeloid leukemia_Homo sapiens_hsa052202.08775314
8Primary immunodeficiency_Homo sapiens_hsa053401.86996206
9Measles_Homo sapiens_hsa051621.80844239
10NF-kappa B signaling pathway_Homo sapiens_hsa040641.79498442
11Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.76310052
12Pancreatic cancer_Homo sapiens_hsa052121.75507837
13Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.73650738
14Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.71926600
15Leishmaniasis_Homo sapiens_hsa051401.69655793
16Viral carcinogenesis_Homo sapiens_hsa052031.66324671
17NOD-like receptor signaling pathway_Homo sapiens_hsa046211.56829773
18Systemic lupus erythematosus_Homo sapiens_hsa053221.55871537
19Osteoclast differentiation_Homo sapiens_hsa043801.54731417
20Endometrial cancer_Homo sapiens_hsa052131.52208226
21Colorectal cancer_Homo sapiens_hsa052101.48003159
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.46218902
23Hepatitis B_Homo sapiens_hsa051611.43491540
24VEGF signaling pathway_Homo sapiens_hsa043701.41700524
25Hematopoietic cell lineage_Homo sapiens_hsa046401.39246665
26Chemokine signaling pathway_Homo sapiens_hsa040621.35138134
27Leukocyte transendothelial migration_Homo sapiens_hsa046701.30833054
28Jak-STAT signaling pathway_Homo sapiens_hsa046301.27252870
29Thyroid cancer_Homo sapiens_hsa052161.23337392
30TNF signaling pathway_Homo sapiens_hsa046681.23089089
31Renal cell carcinoma_Homo sapiens_hsa052111.21969121
32Herpes simplex infection_Homo sapiens_hsa051681.20446012
33Transcriptional misregulation in cancer_Homo sapiens_hsa052021.17595972
34Toll-like receptor signaling pathway_Homo sapiens_hsa046201.17411197
35Choline metabolism in cancer_Homo sapiens_hsa052311.14488348
36mTOR signaling pathway_Homo sapiens_hsa041501.12247983
37Graft-versus-host disease_Homo sapiens_hsa053321.12201456
38Alcoholism_Homo sapiens_hsa050341.09972043
39Toxoplasmosis_Homo sapiens_hsa051451.09128275
40Prostate cancer_Homo sapiens_hsa052151.09114139
41ErbB signaling pathway_Homo sapiens_hsa040121.09029965
42Hepatitis C_Homo sapiens_hsa051601.07590371
43Legionellosis_Homo sapiens_hsa051341.05733522
44Viral myocarditis_Homo sapiens_hsa054161.04757423
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04686274
46Allograft rejection_Homo sapiens_hsa053301.03443529
47Autoimmune thyroid disease_Homo sapiens_hsa053201.02647400
48Influenza A_Homo sapiens_hsa051641.01710043
49Apoptosis_Homo sapiens_hsa042101.00029419
50Dorso-ventral axis formation_Homo sapiens_hsa043200.98651485
51Small cell lung cancer_Homo sapiens_hsa052220.97417163
52Shigellosis_Homo sapiens_hsa051310.97171716
53Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.97086007
54Neurotrophin signaling pathway_Homo sapiens_hsa047220.95540298
55Inositol phosphate metabolism_Homo sapiens_hsa005620.95532057
56Prolactin signaling pathway_Homo sapiens_hsa049170.95071570
57FoxO signaling pathway_Homo sapiens_hsa040680.94155445
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.93981938
59Sphingolipid signaling pathway_Homo sapiens_hsa040710.92247050
60Epstein-Barr virus infection_Homo sapiens_hsa051690.88868951
61Tuberculosis_Homo sapiens_hsa051520.86743339
62MicroRNAs in cancer_Homo sapiens_hsa052060.83784831
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.83608265
64Glioma_Homo sapiens_hsa052140.79764030
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79188387
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.78363425
67Insulin resistance_Homo sapiens_hsa049310.74913683
68Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.74875708
69HIF-1 signaling pathway_Homo sapiens_hsa040660.74535829
70HTLV-I infection_Homo sapiens_hsa051660.73997636
71Regulation of autophagy_Homo sapiens_hsa041400.72817922
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72434268
73Pathways in cancer_Homo sapiens_hsa052000.72337246
74Malaria_Homo sapiens_hsa051440.71224592
75p53 signaling pathway_Homo sapiens_hsa041150.68102382
76Staphylococcus aureus infection_Homo sapiens_hsa051500.65960013
77Intestinal immune network for IgA production_Homo sapiens_hsa046720.64757197
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63706829
79Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63157566
80Bladder cancer_Homo sapiens_hsa052190.62789285
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.60636151
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.59246621
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58076519
84Rap1 signaling pathway_Homo sapiens_hsa040150.56698525
85Endocytosis_Homo sapiens_hsa041440.56181420
86Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.56110953
87African trypanosomiasis_Homo sapiens_hsa051430.56039634
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55623544
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54129512
90Adherens junction_Homo sapiens_hsa045200.52556215
91Insulin signaling pathway_Homo sapiens_hsa049100.52043896
92Antigen processing and presentation_Homo sapiens_hsa046120.52037971
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51511997
94MAPK signaling pathway_Homo sapiens_hsa040100.51411943
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.49645495
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49117698
97Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48573592
98Ras signaling pathway_Homo sapiens_hsa040140.48219112
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46839840
100RNA degradation_Homo sapiens_hsa030180.46205215

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