ZNF772

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.08785723
2nucleobase catabolic process (GO:0046113)4.95079258
3neuron cell-cell adhesion (GO:0007158)4.17179044
4presynaptic membrane assembly (GO:0097105)4.14567949
5presynaptic membrane organization (GO:0097090)3.56859597
6neural tube formation (GO:0001841)3.51254578
7acrosome assembly (GO:0001675)3.49417031
8behavioral response to nicotine (GO:0035095)3.46020478
9rRNA catabolic process (GO:0016075)3.40892897
10regulation of feeding behavior (GO:0060259)3.38508335
11atrial cardiac muscle cell action potential (GO:0086014)3.36287778
12postsynaptic membrane organization (GO:0001941)3.35620003
13retinal ganglion cell axon guidance (GO:0031290)3.33312797
14nonmotile primary cilium assembly (GO:0035058)3.30216822
15protein K11-linked deubiquitination (GO:0035871)3.29438651
16positive regulation of mitochondrial fission (GO:0090141)3.21781044
17response to pheromone (GO:0019236)3.15852334
18L-fucose metabolic process (GO:0042354)3.13384510
19L-fucose catabolic process (GO:0042355)3.13384510
20fucose catabolic process (GO:0019317)3.13384510
21magnesium ion transport (GO:0015693)2.97395009
22membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.95693569
23positive regulation of action potential (GO:0045760)2.91974684
24calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.89688782
25piRNA metabolic process (GO:0034587)2.86444260
26regulation of action potential (GO:0098900)2.86265906
27regulation of acrosome reaction (GO:0060046)2.83719866
28photoreceptor cell maintenance (GO:0045494)2.83585800
29intraciliary transport (GO:0042073)2.80809345
30protein polyglutamylation (GO:0018095)2.77201214
31reflex (GO:0060004)2.74707996
32ncRNA catabolic process (GO:0034661)2.73435239
33positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.71607109
34mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.71607109
35regulation of meiosis I (GO:0060631)2.70147994
36cilium morphogenesis (GO:0060271)2.69349649
37cytoplasmic mRNA processing body assembly (GO:0033962)2.67409929
38retinal cone cell development (GO:0046549)2.67398024
39central nervous system projection neuron axonogenesis (GO:0021952)2.66068716
40behavioral response to ethanol (GO:0048149)2.65596648
41glycosphingolipid biosynthetic process (GO:0006688)2.64922597
42DNA double-strand break processing (GO:0000729)2.64257344
43regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.60860585
44cornea development in camera-type eye (GO:0061303)2.60611506
45regulation of glucokinase activity (GO:0033131)2.59308563
46regulation of hexokinase activity (GO:1903299)2.59308563
47somite development (GO:0061053)2.59215225
48axonal fasciculation (GO:0007413)2.57465182
49olfactory bulb development (GO:0021772)2.57428624
50RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.55735759
51somite rostral/caudal axis specification (GO:0032525)2.53860453
52gamma-aminobutyric acid transport (GO:0015812)2.53687074
53central nervous system neuron axonogenesis (GO:0021955)2.53555623
54detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.52380744
55inner ear receptor stereocilium organization (GO:0060122)2.51471181
56regulation of sarcomere organization (GO:0060297)2.49638038
57protein localization to synapse (GO:0035418)2.48906968
58positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.48406338
59cilium organization (GO:0044782)2.46782434
60meiotic chromosome segregation (GO:0045132)2.46651667
61establishment of protein localization to Golgi (GO:0072600)2.46504819
62sympathetic nervous system development (GO:0048485)2.46195816
63kidney morphogenesis (GO:0060993)2.44519079
64reciprocal meiotic recombination (GO:0007131)2.44513055
65reciprocal DNA recombination (GO:0035825)2.44513055
66kynurenine metabolic process (GO:0070189)2.43522255
67cilium assembly (GO:0042384)2.43400105
68DNA integration (GO:0015074)2.43395246
69limb bud formation (GO:0060174)2.42853885
70neuron recognition (GO:0008038)2.41660676
71negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.41072737
72negative regulation of translation, ncRNA-mediated (GO:0040033)2.41072737
73regulation of translation, ncRNA-mediated (GO:0045974)2.41072737
74indolalkylamine metabolic process (GO:0006586)2.40722346
75spinal cord motor neuron differentiation (GO:0021522)2.39961957
76dendritic spine morphogenesis (GO:0060997)2.38481296
77regulation of cilium movement (GO:0003352)2.36846833
78epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.36447689
79synapse assembly (GO:0007416)2.33589640
80righting reflex (GO:0060013)2.32793946
81appendage development (GO:0048736)2.32645131
82limb development (GO:0060173)2.32645131
83centriole replication (GO:0007099)2.31565899
84interkinetic nuclear migration (GO:0022027)2.30883432
85head development (GO:0060322)2.30850738
86neuronal action potential (GO:0019228)2.30280002
87neurotransmitter-gated ion channel clustering (GO:0072578)2.29923726
88regulation of calcium ion-dependent exocytosis (GO:0017158)2.28691260
89detection of light stimulus involved in sensory perception (GO:0050962)2.27699249
90detection of light stimulus involved in visual perception (GO:0050908)2.27699249
91cellular component assembly involved in morphogenesis (GO:0010927)2.26744315
92G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.26157403
93protein targeting to Golgi (GO:0000042)2.24294151
94negative regulation of DNA-dependent DNA replication (GO:2000104)2.22921309
95histone H3-K4 trimethylation (GO:0080182)2.22307892
96regulation of mitochondrial fission (GO:0090140)2.22240996
97cerebral cortex radially oriented cell migration (GO:0021799)2.22026906
98DNA methylation involved in gamete generation (GO:0043046)2.22021923
99regulation of centriole replication (GO:0046599)2.21870266
100axoneme assembly (GO:0035082)2.21815444

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.67510437
2ZNF274_21170338_ChIP-Seq_K562_Hela3.39892549
3EZH2_22144423_ChIP-Seq_EOC_Human3.35901711
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.88721976
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.87288235
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.82955143
7IGF1R_20145208_ChIP-Seq_DFB_Human2.76123446
8CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.73742800
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.65786767
10FUS_26573619_Chip-Seq_HEK293_Human2.59477256
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.58876364
12TAF15_26573619_Chip-Seq_HEK293_Human2.39033705
13EWS_26573619_Chip-Seq_HEK293_Human2.36284239
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.35155241
15VDR_22108803_ChIP-Seq_LS180_Human2.23510899
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.21713847
17P300_19829295_ChIP-Seq_ESCs_Human2.18400593
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.18100539
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.13241598
20TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.08865523
21PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.94749365
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.93978699
23AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.93889457
24PIAS1_25552417_ChIP-Seq_VCAP_Human1.91690863
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89577355
26SMAD4_21799915_ChIP-Seq_A2780_Human1.84758878
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.75989576
28MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.73846105
29SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71211825
30STAT3_23295773_ChIP-Seq_U87_Human1.66483327
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.65339180
32ER_23166858_ChIP-Seq_MCF-7_Human1.64122114
33TCF4_23295773_ChIP-Seq_U87_Human1.61003233
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.60269840
35UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.59076922
36TOP2B_26459242_ChIP-Seq_MCF-7_Human1.57634682
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53751017
38CBP_20019798_ChIP-Seq_JUKART_Human1.52572311
39IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52572311
40SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52332966
41NR3C1_21868756_ChIP-Seq_MCF10A_Human1.51607804
42AR_25329375_ChIP-Seq_VCAP_Human1.51320488
43MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.50815140
44NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50284240
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.47548646
46* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.46486501
47IRF1_19129219_ChIP-ChIP_H3396_Human1.45901685
48PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45637372
49CBX2_27304074_Chip-Seq_ESCs_Mouse1.45201141
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44976778
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44425869
52POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.44425869
53RNF2_27304074_Chip-Seq_NSC_Mouse1.42858699
54TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.41604704
55BCAT_22108803_ChIP-Seq_LS180_Human1.37782972
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.34803149
57RUNX2_22187159_ChIP-Seq_PCA_Human1.32778892
58REST_21632747_ChIP-Seq_MESCs_Mouse1.32500443
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.29721277
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.24556728
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24114714
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23790535
63PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21063255
64EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20004651
65TP53_22573176_ChIP-Seq_HFKS_Human1.18948231
66MYC_18940864_ChIP-ChIP_HL60_Human1.18387653
67EZH2_27294783_Chip-Seq_NPCs_Mouse1.17383225
68SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16876358
69TCF4_22108803_ChIP-Seq_LS180_Human1.16862787
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.16512351
71HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15580186
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.15417758
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15191890
74SOX2_21211035_ChIP-Seq_LN229_Gbm1.15059547
75TAL1_26923725_Chip-Seq_HPCs_Mouse1.14709351
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.14650452
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14641823
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10264507
79SMAD4_21741376_ChIP-Seq_EPCs_Human1.09935862
80RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08101612
81CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.07429912
82GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07191401
83AR_21572438_ChIP-Seq_LNCaP_Human1.05653766
84KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04497712
85FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03888533
86TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.02967222
87KDM2B_26808549_Chip-Seq_REH_Human1.02590152
88LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01961533
89NANOG_19829295_ChIP-Seq_ESCs_Human1.01462161
90SOX2_19829295_ChIP-Seq_ESCs_Human1.01462161
91CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00506031
92E2F1_18555785_Chip-Seq_ESCs_Mouse0.99101951
93JUN_21703547_ChIP-Seq_K562_Human0.98565493
94REST_18959480_ChIP-ChIP_MESCs_Mouse0.98248301
95P53_22387025_ChIP-Seq_ESCs_Mouse0.97822284
96NFE2_27457419_Chip-Seq_LIVER_Mouse0.96984202
97SOX9_26525672_Chip-Seq_HEART_Mouse0.95473920
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95106849
99PRDM14_20953172_ChIP-Seq_ESCs_Human0.94507086
100STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93170285

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.08691738
2MP0003787_abnormal_imprinting2.98626930
3MP0002102_abnormal_ear_morphology2.37579982
4MP0003122_maternal_imprinting2.28251982
5MP0006292_abnormal_olfactory_placode2.27801878
6MP0002837_dystrophic_cardiac_calcinosis2.26477873
7MP0001529_abnormal_vocalization2.24234147
8MP0003121_genomic_imprinting2.18728073
9MP0006072_abnormal_retinal_apoptosis2.03849576
10MP0006276_abnormal_autonomic_nervous1.93957966
11MP0003880_abnormal_central_pattern1.93508579
12MP0000778_abnormal_nervous_system1.86856017
13MP0005551_abnormal_eye_electrophysiolog1.86620334
14MP0004145_abnormal_muscle_electrophysio1.83868769
15MP0001984_abnormal_olfaction1.82444590
16MP0003890_abnormal_embryonic-extraembry1.82248903
17MP0003011_delayed_dark_adaptation1.78619177
18MP0005253_abnormal_eye_physiology1.77814638
19MP0000569_abnormal_digit_pigmentation1.77572481
20MP0003195_calcinosis1.74478526
21MP0001486_abnormal_startle_reflex1.64305052
22MP0009046_muscle_twitch1.57885564
23MP0004859_abnormal_synaptic_plasticity1.57681210
24MP0004270_analgesia1.55448115
25MP0008789_abnormal_olfactory_epithelium1.53233040
26MP0009745_abnormal_behavioral_response1.49656037
27MP0002234_abnormal_pharynx_morphology1.47842868
28MP0000631_abnormal_neuroendocrine_gland1.47699790
29MP0002272_abnormal_nervous_system1.45716641
30MP0004885_abnormal_endolymph1.43162881
31MP0004924_abnormal_behavior1.42276285
32MP0005386_behavior/neurological_phenoty1.42276285
33MP0004133_heterotaxia1.42243957
34MP0003718_maternal_effect1.40229507
35MP0003635_abnormal_synaptic_transmissio1.39481613
36MP0004142_abnormal_muscle_tone1.37356442
37MP0005499_abnormal_olfactory_system1.37294096
38MP0005394_taste/olfaction_phenotype1.37294096
39MP0005646_abnormal_pituitary_gland1.34728040
40MP0002751_abnormal_autonomic_nervous1.32325063
41MP0002938_white_spotting1.31851940
42MP0003136_yellow_coat_color1.30185111
43MP0004147_increased_porphyrin_level1.28705744
44MP0002638_abnormal_pupillary_reflex1.27813470
45MP0005367_renal/urinary_system_phenotyp1.27109157
46MP0000516_abnormal_urinary_system1.27109157
47MP0002557_abnormal_social/conspecific_i1.25773741
48MP0002735_abnormal_chemical_nociception1.25762177
49MP0002572_abnormal_emotion/affect_behav1.24424170
50MP0003646_muscle_fatigue1.24240166
51MP0002063_abnormal_learning/memory/cond1.24065277
52MP0000427_abnormal_hair_cycle1.23844385
53MP0001968_abnormal_touch/_nociception1.21991434
54MP0004215_abnormal_myocardial_fiber1.21549071
55MP0002184_abnormal_innervation1.19206826
56MP0003937_abnormal_limbs/digits/tail_de1.17518417
57MP0000955_abnormal_spinal_cord1.14462334
58MP0001293_anophthalmia1.14182147
59MP0002067_abnormal_sensory_capabilities1.12046245
60MP0004043_abnormal_pH_regulation1.12030265
61MP0005187_abnormal_penis_morphology1.10739968
62MP0005645_abnormal_hypothalamus_physiol1.10502949
63MP0002064_seizures1.09386700
64MP0002736_abnormal_nociception_after1.08860790
65MP0008058_abnormal_DNA_repair1.07346842
66MP0002653_abnormal_ependyma_morphology1.06692993
67MP0002734_abnormal_mechanical_nocicepti1.05987601
68MP0002233_abnormal_nose_morphology1.03840171
69MP0001485_abnormal_pinna_reflex1.03482863
70MP0002752_abnormal_somatic_nervous1.02211327
71MP0003119_abnormal_digestive_system1.02107849
72MP0002160_abnormal_reproductive_system1.00423767
73MP0000383_abnormal_hair_follicle0.99819552
74MP0005195_abnormal_posterior_eye0.99307700
75MP0004742_abnormal_vestibular_system0.98967298
76MP0002882_abnormal_neuron_morphology0.98379924
77MP0000049_abnormal_middle_ear0.97751290
78MP0005391_vision/eye_phenotype0.97582361
79MP0003567_abnormal_fetal_cardiomyocyte0.97365246
80MP0000647_abnormal_sebaceous_gland0.96943872
81MP0001986_abnormal_taste_sensitivity0.96754468
82MP0002909_abnormal_adrenal_gland0.96377581
83MP0004484_altered_response_of0.94852113
84MP0008872_abnormal_physiological_respon0.94597538
85MP0002152_abnormal_brain_morphology0.94342199
86MP0004811_abnormal_neuron_physiology0.94318637
87MP0001970_abnormal_pain_threshold0.91642411
88MP0002928_abnormal_bile_duct0.91162202
89MP0003861_abnormal_nervous_system0.87703228
90MP0003755_abnormal_palate_morphology0.86131319
91MP0002733_abnormal_thermal_nociception0.85402695
92MP0004085_abnormal_heartbeat0.83867933
93MP0005248_abnormal_Harderian_gland0.83679919
94MP0002229_neurodegeneration0.81006195
95MP0001188_hyperpigmentation0.78797308
96MP0003283_abnormal_digestive_organ0.78462394
97MP0001324_abnormal_eye_pigmentation0.78401994
98MP0001286_abnormal_eye_development0.77620276
99MP0003698_abnormal_male_reproductive0.77408743
100MP0003137_abnormal_impulse_conducting0.77236157

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.80322002
2Pancreatic fibrosis (HP:0100732)3.76114219
3Hyperventilation (HP:0002883)3.67210448
4Medial flaring of the eyebrow (HP:0010747)3.54349969
5Nephronophthisis (HP:0000090)3.32176676
6Nephrogenic diabetes insipidus (HP:0009806)3.23640337
7Gait imbalance (HP:0002141)3.23210686
8True hermaphroditism (HP:0010459)3.18051310
9Congenital primary aphakia (HP:0007707)3.09691189
10Abnormality of the renal medulla (HP:0100957)3.08577700
11Molar tooth sign on MRI (HP:0002419)3.04687748
12Abnormality of midbrain morphology (HP:0002418)3.04687748
13Chronic hepatic failure (HP:0100626)2.99730790
14Abnormality of the renal cortex (HP:0011035)2.98725386
15Drooling (HP:0002307)2.88975617
16Genital tract atresia (HP:0001827)2.87356403
17Lissencephaly (HP:0001339)2.73318262
18Vaginal atresia (HP:0000148)2.69880583
19Focal seizures (HP:0007359)2.67654012
20Excessive salivation (HP:0003781)2.56550740
21Intestinal atresia (HP:0011100)2.55606476
22Broad-based gait (HP:0002136)2.55489166
23Gaze-evoked nystagmus (HP:0000640)2.55010857
24Poor coordination (HP:0002370)2.53672760
25Focal motor seizures (HP:0011153)2.50477709
26Abnormality of the labia minora (HP:0012880)2.48082449
27Oligodactyly (hands) (HP:0001180)2.39323248
28Bile duct proliferation (HP:0001408)2.38214257
29Abnormal biliary tract physiology (HP:0012439)2.38214257
30Renal cortical cysts (HP:0000803)2.35625720
31Aplasia/Hypoplasia of the tibia (HP:0005772)2.31367169
32Pachygyria (HP:0001302)2.29141092
33Inability to walk (HP:0002540)2.23700924
34Aplasia/Hypoplasia of the tongue (HP:0010295)2.23553168
35Volvulus (HP:0002580)2.21653038
36Type II lissencephaly (HP:0007260)2.19829679
37Febrile seizures (HP:0002373)2.19449198
38Supernumerary spleens (HP:0009799)2.18755965
39Attenuation of retinal blood vessels (HP:0007843)2.16550833
40Congenital stationary night blindness (HP:0007642)2.15216118
41Cerebellar dysplasia (HP:0007033)2.15109469
42Progressive inability to walk (HP:0002505)2.13370514
43Congenital hepatic fibrosis (HP:0002612)2.11898949
44Hypsarrhythmia (HP:0002521)2.10768945
45Cystic liver disease (HP:0006706)2.10427863
46Postaxial hand polydactyly (HP:0001162)2.09572353
47Progressive cerebellar ataxia (HP:0002073)2.08618368
48Protruding tongue (HP:0010808)2.07680834
49Genetic anticipation (HP:0003743)2.05706103
50Colon cancer (HP:0003003)2.05434431
51Tubular atrophy (HP:0000092)2.03871668
52Tubulointerstitial nephritis (HP:0001970)2.03458251
53EEG with generalized epileptiform discharges (HP:0011198)2.03233573
54Postaxial foot polydactyly (HP:0001830)2.02168148
55Anencephaly (HP:0002323)1.99005249
56Polydipsia (HP:0001959)1.97087346
57Abnormal drinking behavior (HP:0030082)1.97087346
58Epileptiform EEG discharges (HP:0011182)1.97055855
59Fair hair (HP:0002286)1.95220992
60Hepatoblastoma (HP:0002884)1.89417097
61Narrow forehead (HP:0000341)1.88420158
62Specific learning disability (HP:0001328)1.87355039
63Short tibia (HP:0005736)1.85698571
64Papillary thyroid carcinoma (HP:0002895)1.84388813
65Optic nerve hypoplasia (HP:0000609)1.84108327
66Neoplasm of the adrenal cortex (HP:0100641)1.81780434
67Thyroid-stimulating hormone excess (HP:0002925)1.78710400
68Polyphagia (HP:0002591)1.78361135
69Broad foot (HP:0001769)1.78255557
70Sclerocornea (HP:0000647)1.78114349
71Abnormal rod and cone electroretinograms (HP:0008323)1.77641938
72Short foot (HP:0001773)1.77171099
73Chorioretinal atrophy (HP:0000533)1.75197401
74Hyperglycinemia (HP:0002154)1.74332903
75Pheochromocytoma (HP:0002666)1.73225833
76Neuroendocrine neoplasm (HP:0100634)1.72899643
77Absent speech (HP:0001344)1.71639355
78Astigmatism (HP:0000483)1.71612092
79Furrowed tongue (HP:0000221)1.71432044
80Hypothermia (HP:0002045)1.69495540
81Abolished electroretinogram (ERG) (HP:0000550)1.68334962
82Dandy-Walker malformation (HP:0001305)1.67132021
83Hypoplastic nipples (HP:0002557)1.66740762
84Aqueductal stenosis (HP:0002410)1.66643075
85Partial agenesis of the corpus callosum (HP:0001338)1.66346687
86Calf muscle hypertrophy (HP:0008981)1.65286553
87Preaxial hand polydactyly (HP:0001177)1.65174725
88Micropenis (HP:0000054)1.64721612
89Cutaneous finger syndactyly (HP:0010554)1.64008690
90Polyuria (HP:0000103)1.63664482
91Left ventricular hypertrophy (HP:0001712)1.62823967
92Labial hypoplasia (HP:0000066)1.62809195
93Hip dysplasia (HP:0001385)1.62126344
94Multicystic kidney dysplasia (HP:0000003)1.61331786
95Broad alveolar ridges (HP:0000187)1.61129644
96Abnormality of macular pigmentation (HP:0008002)1.60387666
97Bony spicule pigmentary retinopathy (HP:0007737)1.59737358
98Occipital encephalocele (HP:0002085)1.59572108
99Tubulointerstitial abnormality (HP:0001969)1.58784231
100Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.58665529

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.72044147
2MAP4K23.24823395
3BMPR1B3.10519552
4CASK3.03073986
5MARK12.94099954
6MAP3K42.85681150
7WNK32.44158005
8ACVR1B2.32368708
9NUAK12.29023230
10MAP2K72.14515627
11ZAK2.06126697
12CAMKK21.94030009
13MAPK131.86341097
14TRIM281.74233620
15TNIK1.72605846
16MKNK21.68426939
17PINK11.55843623
18OBSCN1.53746202
19BCR1.47497201
20GRK11.35564051
21ERBB31.35016623
22MKNK11.33010274
23ADRBK21.32703779
24PAK31.32612293
25CSNK1G11.30123500
26EPHA41.27826199
27STK38L1.25310876
28AKT31.25230892
29EPHA31.25106240
30CSNK1G21.20835825
31CAMK1G1.16255459
32FGFR21.15012295
33CAMK1D1.14753259
34CCNB11.09386071
35LATS11.09183712
36SGK21.05781930
37DAPK21.05589276
38DYRK21.03398127
39PHKG10.99383150
40PHKG20.99383150
41TGFBR10.95329036
42PRKCE0.95070388
43CSNK1A1L0.93039203
44CAMK40.92991222
45NTRK20.91147059
46CSNK1G30.90823038
47INSRR0.90657930
48MAP2K40.88772779
49BRD40.86238098
50FLT30.85830590
51NTRK30.85637311
52PRKCG0.82508818
53SRPK10.80095076
54STK30.79228752
55MAP3K90.75589697
56BRSK20.73979627
57NLK0.71950324
58TAOK30.70723316
59DYRK30.69437496
60SIK20.68855926
61SGK2230.67294348
62SGK4940.67294348
63CDK30.67265182
64FER0.64962398
65TIE10.64683855
66WNK40.64606643
67STK390.62765921
68PKN10.61535638
69PLK40.60562761
70OXSR10.60064372
71ADRBK10.59996273
72RPS6KA40.59495279
73PLK20.59321665
74GRK70.53959317
75PRKAA10.53195710
76CAMK10.51781449
77CAMK2A0.51756800
78PNCK0.49991203
79VRK10.49579758
80STK110.49204819
81DYRK1A0.49081385
82TLK10.48211176
83PLK30.48115770
84MINK10.47043780
85PLK10.43822232
86CSNK1D0.43755388
87ATM0.43500187
88PRKCZ0.43288436
89SGK30.42937212
90RPS6KA50.42929690
91BCKDK0.39827944
92CSNK1E0.38458427
93CDK50.37502544
94PRKACA0.37395481
95CDK80.36836426
96CSNK1A10.33993510
97PRKACB0.32856958
98STK160.32381809
99TYRO30.30979296
100PRKAA20.30485168

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.85721701
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.65310311
3Phototransduction_Homo sapiens_hsa047442.47311967
4Butanoate metabolism_Homo sapiens_hsa006502.35193269
5Selenocompound metabolism_Homo sapiens_hsa004502.21058127
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.15522682
7Propanoate metabolism_Homo sapiens_hsa006402.14604318
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.13923887
9Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.10145458
10Basal transcription factors_Homo sapiens_hsa030222.09452815
11Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.06348811
12Regulation of autophagy_Homo sapiens_hsa041401.97673641
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.87229314
14Linoleic acid metabolism_Homo sapiens_hsa005911.77331849
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.71664405
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.68258998
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66252580
18Fanconi anemia pathway_Homo sapiens_hsa034601.63358362
19Circadian rhythm_Homo sapiens_hsa047101.63200089
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.60375208
21Ether lipid metabolism_Homo sapiens_hsa005651.57970701
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.57737957
23GABAergic synapse_Homo sapiens_hsa047271.57321473
24Insulin secretion_Homo sapiens_hsa049111.51051523
25Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.50586297
26Taste transduction_Homo sapiens_hsa047421.45431129
27RNA degradation_Homo sapiens_hsa030181.44150626
28Tryptophan metabolism_Homo sapiens_hsa003801.36872328
29Maturity onset diabetes of the young_Homo sapiens_hsa049501.35824642
30Morphine addiction_Homo sapiens_hsa050321.30954641
31Circadian entrainment_Homo sapiens_hsa047131.30884814
32Glutamatergic synapse_Homo sapiens_hsa047241.30877481
33Caffeine metabolism_Homo sapiens_hsa002321.28880797
34Dopaminergic synapse_Homo sapiens_hsa047281.25841021
35Protein export_Homo sapiens_hsa030601.22962519
36Nitrogen metabolism_Homo sapiens_hsa009101.17200254
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.16371171
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.16214697
39Dorso-ventral axis formation_Homo sapiens_hsa043201.14008662
40Non-homologous end-joining_Homo sapiens_hsa034501.13132750
41Ovarian steroidogenesis_Homo sapiens_hsa049131.11299330
42Serotonergic synapse_Homo sapiens_hsa047261.11279433
43Steroid biosynthesis_Homo sapiens_hsa001001.10641909
44Long-term depression_Homo sapiens_hsa047301.09620870
45Hedgehog signaling pathway_Homo sapiens_hsa043401.01477919
46Peroxisome_Homo sapiens_hsa041461.00636773
47Olfactory transduction_Homo sapiens_hsa047400.99198419
48beta-Alanine metabolism_Homo sapiens_hsa004100.99037432
49Lysine degradation_Homo sapiens_hsa003100.95138046
50Cysteine and methionine metabolism_Homo sapiens_hsa002700.90355574
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90331657
52Axon guidance_Homo sapiens_hsa043600.89086482
53Homologous recombination_Homo sapiens_hsa034400.85225205
54Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.83054962
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81683840
56Salivary secretion_Homo sapiens_hsa049700.81556789
57RNA transport_Homo sapiens_hsa030130.78756203
58Alcoholism_Homo sapiens_hsa050340.77589190
59Cholinergic synapse_Homo sapiens_hsa047250.77492659
60RNA polymerase_Homo sapiens_hsa030200.76113472
61Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.73444840
62Cocaine addiction_Homo sapiens_hsa050300.72201537
63Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.70642360
64Retinol metabolism_Homo sapiens_hsa008300.70407472
65Steroid hormone biosynthesis_Homo sapiens_hsa001400.69448934
66Calcium signaling pathway_Homo sapiens_hsa040200.68870678
67Hippo signaling pathway_Homo sapiens_hsa043900.68503979
68ABC transporters_Homo sapiens_hsa020100.66552219
69Basal cell carcinoma_Homo sapiens_hsa052170.65975276
70Amphetamine addiction_Homo sapiens_hsa050310.65460244
71Renin secretion_Homo sapiens_hsa049240.64705589
72Oxytocin signaling pathway_Homo sapiens_hsa049210.63637293
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63544438
74mRNA surveillance pathway_Homo sapiens_hsa030150.60248583
75Fatty acid metabolism_Homo sapiens_hsa012120.60163665
76Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58540261
77Oocyte meiosis_Homo sapiens_hsa041140.57607652
78Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57256769
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56204009
80Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.55953738
81cAMP signaling pathway_Homo sapiens_hsa040240.53906676
82Cardiac muscle contraction_Homo sapiens_hsa042600.52526734
83One carbon pool by folate_Homo sapiens_hsa006700.52145475
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51464857
85Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51427731
86FoxO signaling pathway_Homo sapiens_hsa040680.51402979
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.50684002
88Wnt signaling pathway_Homo sapiens_hsa043100.49467765
89Collecting duct acid secretion_Homo sapiens_hsa049660.47619968
90cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45876102
91Pyruvate metabolism_Homo sapiens_hsa006200.45799917
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45771236
93Synaptic vesicle cycle_Homo sapiens_hsa047210.45617476
94Glucagon signaling pathway_Homo sapiens_hsa049220.45579931
95Fatty acid degradation_Homo sapiens_hsa000710.45430883
96Type II diabetes mellitus_Homo sapiens_hsa049300.43235879
97Base excision repair_Homo sapiens_hsa034100.42261021
98Metabolic pathways_Homo sapiens_hsa011000.41670599
99Purine metabolism_Homo sapiens_hsa002300.40501314
100TGF-beta signaling pathway_Homo sapiens_hsa043500.39885898

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