ZNF747

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.21843955
2pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.29878009
3L-fucose catabolic process (GO:0042355)4.26996732
4fucose catabolic process (GO:0019317)4.26996732
5L-fucose metabolic process (GO:0042354)4.26996732
6protein complex biogenesis (GO:0070271)4.23916896
7mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.12129969
8mitochondrial respiratory chain complex I assembly (GO:0032981)4.12129969
9NADH dehydrogenase complex assembly (GO:0010257)4.12129969
10indole-containing compound catabolic process (GO:0042436)4.12002023
11indolalkylamine catabolic process (GO:0046218)4.12002023
12tryptophan catabolic process (GO:0006569)4.12002023
13ubiquinone biosynthetic process (GO:0006744)4.00032035
14mitochondrial respiratory chain complex assembly (GO:0033108)3.99692642
15base-excision repair, AP site formation (GO:0006285)3.83370818
16pyrimidine nucleotide catabolic process (GO:0006244)3.82867417
17viral transcription (GO:0019083)3.74196011
18maturation of SSU-rRNA (GO:0030490)3.57283420
19translational termination (GO:0006415)3.53012644
20negative regulation of telomere maintenance (GO:0032205)3.52416956
21kynurenine metabolic process (GO:0070189)3.51430818
22behavioral response to nicotine (GO:0035095)3.50224840
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.50221035
24preassembly of GPI anchor in ER membrane (GO:0016254)3.48540926
25protein-cofactor linkage (GO:0018065)3.44276513
26energy coupled proton transport, down electrochemical gradient (GO:0015985)3.42816772
27ATP synthesis coupled proton transport (GO:0015986)3.42816772
28ubiquinone metabolic process (GO:0006743)3.42729039
29cytochrome complex assembly (GO:0017004)3.42553983
30tryptophan metabolic process (GO:0006568)3.42266238
31platelet dense granule organization (GO:0060155)3.39289811
32deoxyribonucleotide catabolic process (GO:0009264)3.37393290
33indolalkylamine metabolic process (GO:0006586)3.36916293
34quinone biosynthetic process (GO:1901663)3.36578693
35negative regulation of cAMP-mediated signaling (GO:0043951)3.35921267
36respiratory chain complex IV assembly (GO:0008535)3.35898697
37ribosomal small subunit biogenesis (GO:0042274)3.31109073
38ribosomal small subunit assembly (GO:0000028)3.27745777
39water-soluble vitamin biosynthetic process (GO:0042364)3.27015035
40translational elongation (GO:0006414)3.19812240
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.18017340
42electron transport chain (GO:0022900)3.17018170
43cellular biogenic amine catabolic process (GO:0042402)3.12917822
44amine catabolic process (GO:0009310)3.12917822
45exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.12539254
46respiratory electron transport chain (GO:0022904)3.12514747
47pseudouridine synthesis (GO:0001522)3.10330402
48nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.09830704
49mannosylation (GO:0097502)3.01714303
50GTP biosynthetic process (GO:0006183)3.00148125
51piRNA metabolic process (GO:0034587)2.97825959
52deoxyribose phosphate catabolic process (GO:0046386)2.95701934
53aromatic amino acid family catabolic process (GO:0009074)2.93073205
54SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.92663438
55protein targeting to ER (GO:0045047)2.91684134
56purine deoxyribonucleotide catabolic process (GO:0009155)2.90732076
57cotranslational protein targeting to membrane (GO:0006613)2.86234471
58regulation of mitochondrial translation (GO:0070129)2.80859630
59positive regulation of prostaglandin secretion (GO:0032308)2.80390989
60positive regulation of fatty acid transport (GO:2000193)2.78023664
61negative regulation of B cell apoptotic process (GO:0002903)2.75834432
62protein localization to endoplasmic reticulum (GO:0070972)2.74749992
63establishment of protein localization to endoplasmic reticulum (GO:0072599)2.71072350
64viral life cycle (GO:0019058)2.70851051
65cellular ketone body metabolic process (GO:0046950)2.69440949
66UTP metabolic process (GO:0046051)2.68341152
67iron-sulfur cluster assembly (GO:0016226)2.65199224
68metallo-sulfur cluster assembly (GO:0031163)2.65199224
69tRNA modification (GO:0006400)2.62607969
70UTP biosynthetic process (GO:0006228)2.62410629
71oxidative demethylation (GO:0070989)2.61873389
72protein polyglutamylation (GO:0018095)2.56360982
73negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.55836403
74tRNA processing (GO:0008033)2.55484765
75S-adenosylmethionine metabolic process (GO:0046500)2.51504993
76peptidyl-histidine modification (GO:0018202)2.50274491
77response to pheromone (GO:0019236)2.47821935
78somatic hypermutation of immunoglobulin genes (GO:0016446)2.47287833
79somatic diversification of immune receptors via somatic mutation (GO:0002566)2.47287833
80hydrogen ion transmembrane transport (GO:1902600)2.46565765
81anterograde synaptic vesicle transport (GO:0048490)2.45226841
82positive regulation of defense response to virus by host (GO:0002230)2.45142071
83indole-containing compound metabolic process (GO:0042430)2.43817341
84cellular component biogenesis (GO:0044085)2.43115069
85nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.42291524
86RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.42109678
87tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.42109678
88positive regulation of protein homodimerization activity (GO:0090073)2.41926791
89chaperone-mediated protein transport (GO:0072321)2.41882610
90epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.41295517
91cellular protein complex disassembly (GO:0043624)2.41120091
92NAD biosynthetic process (GO:0009435)2.40616420
93positive regulation of icosanoid secretion (GO:0032305)2.40242623
94protein localization to cilium (GO:0061512)2.38497118
95phosphorylated carbohydrate dephosphorylation (GO:0046838)2.38171690
96inositol phosphate dephosphorylation (GO:0046855)2.38171690
97L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.37792342
98regulation of nuclear cell cycle DNA replication (GO:0033262)2.36172588
99axoneme assembly (GO:0035082)2.34450782
100proton transport (GO:0015992)2.34051111

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.98685537
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.18433700
3ZNF274_21170338_ChIP-Seq_K562_Hela3.31264828
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.04395116
5* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.04190919
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.93464103
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.81539998
8NOTCH1_21737748_ChIP-Seq_TLL_Human2.75146430
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.62987680
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.50850506
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.49258091
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.49245296
13VDR_23849224_ChIP-Seq_CD4+_Human2.29730182
14* FOXP3_21729870_ChIP-Seq_TREG_Human2.21295814
15SRF_21415370_ChIP-Seq_HL-1_Mouse2.18849931
16VDR_22108803_ChIP-Seq_LS180_Human2.15321449
17IRF1_19129219_ChIP-ChIP_H3396_Human2.09950606
18CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.07470969
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.05893075
20CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.04575915
21ELF1_17652178_ChIP-ChIP_JURKAT_Human1.99427229
22MYC_18940864_ChIP-ChIP_HL60_Human1.97010670
23PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.95432329
24* CIITA_25753668_ChIP-Seq_RAJI_Human1.91133001
25CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.85280340
26EZH2_22144423_ChIP-Seq_EOC_Human1.82872089
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74339602
28EGR1_23403033_ChIP-Seq_LIVER_Mouse1.66558235
29EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.62203686
30KDM5A_27292631_Chip-Seq_BREAST_Human1.53086806
31* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.52086565
32GABP_19822575_ChIP-Seq_HepG2_Human1.51895706
33* ERA_21632823_ChIP-Seq_H3396_Human1.51551698
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.48748148
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45175432
36BCL6_27268052_Chip-Seq_Bcells_Human1.41758094
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.40323115
38TP53_22573176_ChIP-Seq_HFKS_Human1.39920189
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.38055687
40ELF1_20517297_ChIP-Seq_JURKAT_Human1.37764165
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37491774
42RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.35928966
43CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35043275
44* E2F1_20622854_ChIP-Seq_HELA_Human1.32961562
45XRN2_22483619_ChIP-Seq_HELA_Human1.29645144
46LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29398624
47HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.29296624
48YY1_22570637_ChIP-Seq_MALME-3M_Human1.27535314
49VDR_21846776_ChIP-Seq_THP-1_Human1.26324919
50CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.25942475
51NANOG_20526341_ChIP-Seq_ESCs_Human1.25109565
52GATA3_21878914_ChIP-Seq_MCF-7_Human1.25078946
53VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.24432233
54MYC_18358816_ChIP-ChIP_MESCs_Mouse1.24330644
55IGF1R_20145208_ChIP-Seq_DFB_Human1.23591233
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.21185251
57* PHF8_20622854_ChIP-Seq_HELA_Human1.19353614
58* P300_27268052_Chip-Seq_Bcells_Human1.17977829
59* CTCF_20526341_ChIP-Seq_ESCs_Human1.17188526
60P68_20966046_ChIP-Seq_HELA_Human1.17127790
61* TTF2_22483619_ChIP-Seq_HELA_Human1.17121899
62OCT4_20526341_ChIP-Seq_ESCs_Human1.15774916
63BP1_19119308_ChIP-ChIP_Hs578T_Human1.13320601
64* BCOR_27268052_Chip-Seq_Bcells_Human1.12597996
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12256716
66TAF2_19829295_ChIP-Seq_ESCs_Human1.11427630
67FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10173179
68* FOXP1_21924763_ChIP-Seq_HESCs_Human1.10163285
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.08229241
70AR_20517297_ChIP-Seq_VCAP_Human1.06789145
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.06428692
72CTBP1_25329375_ChIP-Seq_LNCAP_Human1.06367531
73P53_21459846_ChIP-Seq_SAOS-2_Human1.05115786
74GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05049288
75* RAC3_21632823_ChIP-Seq_H3396_Human1.05008589
76NCOR_22424771_ChIP-Seq_293T_Human1.03222681
77PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02082698
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01427242
79* MYC_19829295_ChIP-Seq_ESCs_Human1.00397449
80SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00068340
81EWS_26573619_Chip-Seq_HEK293_Human0.98223161
82FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97343798
83FOXA1_25329375_ChIP-Seq_VCAP_Human0.97343798
84FUS_26573619_Chip-Seq_HEK293_Human0.97018409
85CTCF_18555785_ChIP-Seq_MESCs_Mouse0.96729239
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96703180
87SA1_27219007_Chip-Seq_Bcells_Human0.96476669
88CTCF_26484167_Chip-Seq_Bcells_Mouse0.95927694
89SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95092304
90CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.94748383
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94746084
92TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.94611302
93GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93304542
94SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93194051
95BMI1_23680149_ChIP-Seq_NPCS_Mouse0.91829208
96SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91460988
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89761750
98MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89731950
99EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.89281676
100E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.88138218

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode2.99743872
2MP0002653_abnormal_ependyma_morphology2.77378603
3MP0003195_calcinosis2.64332724
4MP0008877_abnormal_DNA_methylation2.63099035
5MP0002837_dystrophic_cardiac_calcinosis2.60264670
6MP0003787_abnormal_imprinting2.34375314
7MP0001968_abnormal_touch/_nociception2.10050715
8MP0002163_abnormal_gland_morphology2.07671443
9MP0005645_abnormal_hypothalamus_physiol2.04496168
10MP0006072_abnormal_retinal_apoptosis1.94797623
11MP0001986_abnormal_taste_sensitivity1.87017153
12MP0008875_abnormal_xenobiotic_pharmacok1.85654607
13MP0002138_abnormal_hepatobiliary_system1.82803468
14MP0001764_abnormal_homeostasis1.82745026
15MP0008058_abnormal_DNA_repair1.77734447
16MP0003011_delayed_dark_adaptation1.73211063
17MP0002876_abnormal_thyroid_physiology1.71126276
18MP0005551_abnormal_eye_electrophysiolog1.69352490
19MP0006036_abnormal_mitochondrial_physio1.68865228
20MP0002638_abnormal_pupillary_reflex1.65342417
21MP0004133_heterotaxia1.63373860
22MP0008995_early_reproductive_senescence1.61976091
23MP0005075_abnormal_melanosome_morpholog1.58560590
24MP0002102_abnormal_ear_morphology1.55273928
25MP0005646_abnormal_pituitary_gland1.55025545
26MP0008789_abnormal_olfactory_epithelium1.54036288
27MP0005671_abnormal_response_to1.50466233
28MP0004043_abnormal_pH_regulation1.49590627
29MP0005379_endocrine/exocrine_gland_phen1.48177681
30MP0008872_abnormal_physiological_respon1.48173810
31MP0005394_taste/olfaction_phenotype1.39821081
32MP0005499_abnormal_olfactory_system1.39821081
33MP0002928_abnormal_bile_duct1.32142281
34MP0004142_abnormal_muscle_tone1.29023557
35MP0005253_abnormal_eye_physiology1.28330738
36MP0002277_abnormal_respiratory_mucosa1.24239704
37MP0003806_abnormal_nucleotide_metabolis1.22351794
38MP0003718_maternal_effect1.22100445
39MP0009278_abnormal_bone_marrow1.19483795
40MP0003646_muscle_fatigue1.19156435
41MP0002736_abnormal_nociception_after1.19092268
42MP0005360_urolithiasis1.18369619
43MP0005084_abnormal_gallbladder_morpholo1.18268539
44MP0000631_abnormal_neuroendocrine_gland1.16549803
45MP0000372_irregular_coat_pigmentation1.15085396
46MP0001800_abnormal_humoral_immune1.13870166
47MP0006035_abnormal_mitochondrial_morpho1.13644140
48MP0001905_abnormal_dopamine_level1.12869005
49MP0003880_abnormal_central_pattern1.12002527
50MP0009333_abnormal_splenocyte_physiolog1.11889111
51MP0010094_abnormal_chromosome_stability1.11817770
52MP0002160_abnormal_reproductive_system1.11371537
53MP0005389_reproductive_system_phenotype1.11308204
54MP0003763_abnormal_thymus_physiology1.09687096
55MP0009379_abnormal_foot_pigmentation1.09166076
56MP0002132_abnormal_respiratory_system1.07879044
57MP0000685_abnormal_immune_system1.06395586
58MP0004130_abnormal_muscle_cell1.04348586
59MP0003172_abnormal_lysosome_physiology1.04219338
60MP0005365_abnormal_bile_salt1.02578918
61MP0001293_anophthalmia1.00841851
62MP0004147_increased_porphyrin_level0.98785776
63MP0003786_premature_aging0.98063010
64MP0010386_abnormal_urinary_bladder0.97896488
65MP0001919_abnormal_reproductive_system0.97257673
66MP0005220_abnormal_exocrine_pancreas0.95782702
67MP0003121_genomic_imprinting0.95216562
68MP0009745_abnormal_behavioral_response0.93918723
69MP0006276_abnormal_autonomic_nervous0.92379014
70MP0005085_abnormal_gallbladder_physiolo0.92085371
71MP0001984_abnormal_olfaction0.90857560
72MP0002733_abnormal_thermal_nociception0.90824530
73MP0002693_abnormal_pancreas_physiology0.89949185
74MP0004885_abnormal_endolymph0.88972893
75MP0005332_abnormal_amino_acid0.88767653
76MP0003136_yellow_coat_color0.88440868
77MP0001485_abnormal_pinna_reflex0.87061508
78MP0001790_abnormal_immune_system0.86164415
79MP0005387_immune_system_phenotype0.86164415
80MP0001270_distended_abdomen0.85400211
81MP0001944_abnormal_pancreas_morphology0.85246183
82MP0002272_abnormal_nervous_system0.84591309
83MP0003283_abnormal_digestive_organ0.84454060
84MP0004145_abnormal_muscle_electrophysio0.81183582
85MP0005167_abnormal_blood-brain_barrier0.80422496
86MP0001819_abnormal_immune_cell0.80383756
87MP0002420_abnormal_adaptive_immunity0.80252171
88MP0001501_abnormal_sleep_pattern0.79685426
89MP0004742_abnormal_vestibular_system0.79632823
90MP0002735_abnormal_chemical_nociception0.79628014
91MP0002723_abnormal_immune_serum0.79616728
92MP0000689_abnormal_spleen_morphology0.79555753
93MP0002234_abnormal_pharynx_morphology0.79460751
94MP0005174_abnormal_tail_pigmentation0.79444809
95MP0001835_abnormal_antigen_presentation0.78720138
96MP0005195_abnormal_posterior_eye0.77156263
97MP0003122_maternal_imprinting0.77057784
98MP0009764_decreased_sensitivity_to0.76476684
99MP0001486_abnormal_startle_reflex0.76394502
100MP0003186_abnormal_redox_activity0.75703303

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)4.36318968
2Abnormal number of erythroid precursors (HP:0012131)3.95756050
3Abnormality of cells of the erythroid lineage (HP:0012130)3.68572598
4Pancreatic cysts (HP:0001737)3.55221742
5Mitochondrial inheritance (HP:0001427)3.41376199
6Hepatocellular necrosis (HP:0001404)3.36769399
7Hepatic necrosis (HP:0002605)3.31301953
8Type II lissencephaly (HP:0007260)3.28149594
9Bile duct proliferation (HP:0001408)3.25844699
10Abnormal biliary tract physiology (HP:0012439)3.25844699
11Acute necrotizing encephalopathy (HP:0006965)3.23735728
12Abnormal mitochondria in muscle tissue (HP:0008316)3.06523680
13Abnormality of the renal cortex (HP:0011035)3.04264480
14Increased CSF lactate (HP:0002490)2.97253803
15Acute encephalopathy (HP:0006846)2.97153223
16Pancreatic fibrosis (HP:0100732)2.94468867
17Molar tooth sign on MRI (HP:0002419)2.90247872
18Abnormality of midbrain morphology (HP:0002418)2.90247872
19Progressive macrocephaly (HP:0004481)2.77193765
20Lipid accumulation in hepatocytes (HP:0006561)2.68727713
213-Methylglutaconic aciduria (HP:0003535)2.61662565
22Medial flaring of the eyebrow (HP:0010747)2.56755830
23Abnormal rod and cone electroretinograms (HP:0008323)2.56196097
24Chronic hepatic failure (HP:0100626)2.54806929
25Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.46060533
26Reticulocytopenia (HP:0001896)2.44059384
27True hermaphroditism (HP:0010459)2.43400182
28Nephronophthisis (HP:0000090)2.41900944
29Renal cortical cysts (HP:0000803)2.39791095
30Abolished electroretinogram (ERG) (HP:0000550)2.35385921
31Abnormal protein glycosylation (HP:0012346)2.34337203
32Abnormal glycosylation (HP:0012345)2.34337203
33Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.34337203
34Abnormal protein N-linked glycosylation (HP:0012347)2.34337203
35Polydipsia (HP:0001959)2.33391021
36Abnormal drinking behavior (HP:0030082)2.33391021
37Polyuria (HP:0000103)2.32464409
38Increased muscle lipid content (HP:0009058)2.31276546
39Increased serum lactate (HP:0002151)2.31038779
40Abnormality of the renal medulla (HP:0100957)2.28405631
41Absent rod-and cone-mediated responses on ERG (HP:0007688)2.26638209
42Stomach cancer (HP:0012126)2.21665480
43Colon cancer (HP:0003003)2.18305078
44Attenuation of retinal blood vessels (HP:0007843)2.17807970
45Abnormality of B cell number (HP:0010975)2.17328664
46Reduced antithrombin III activity (HP:0001976)2.15901223
47Lactic acidosis (HP:0003128)2.15828354
48Ketosis (HP:0001946)2.15379062
49Cystic liver disease (HP:0006706)2.15164426
50Absent thumb (HP:0009777)2.14377067
51Optic disc pallor (HP:0000543)2.11245582
52Cerebellar dysplasia (HP:0007033)2.10805572
53Tubular atrophy (HP:0000092)2.10032108
54Asplenia (HP:0001746)2.08376671
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.07550403
56Cerebral edema (HP:0002181)2.06478493
57Clumsiness (HP:0002312)2.06402134
58Aplasia/Hypoplasia of the spleen (HP:0010451)2.04817135
59Panhypogammaglobulinemia (HP:0003139)2.03985879
60Pendular nystagmus (HP:0012043)2.02281722
61Delayed CNS myelination (HP:0002188)2.00043050
62Lethargy (HP:0001254)1.98806623
63Type I transferrin isoform profile (HP:0003642)1.98581330
64Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.98424498
65Decreased activity of mitochondrial respiratory chain (HP:0008972)1.98424498
66Hypoplasia of the pons (HP:0012110)1.96113149
67Increased intramyocellular lipid droplets (HP:0012240)1.95918940
68Increased hepatocellular lipid droplets (HP:0006565)1.90665726
69Abnormality of dicarboxylic acid metabolism (HP:0010995)1.90664495
70Dicarboxylic aciduria (HP:0003215)1.90664495
71Hypomagnesemia (HP:0002917)1.90310923
72Congenital hepatic fibrosis (HP:0002612)1.89041398
73Supernumerary spleens (HP:0009799)1.88460494
74Abnormal urine output (HP:0012590)1.86868109
75Decreased electroretinogram (ERG) amplitude (HP:0000654)1.86161799
76Respiratory failure (HP:0002878)1.85126016
77Hyperglycinuria (HP:0003108)1.84486006
78Abnormality of the pons (HP:0007361)1.83724540
79Decreased central vision (HP:0007663)1.83706233
80Abnormal delayed hypersensitivity skin test (HP:0002963)1.82756419
81Pallor (HP:0000980)1.80304068
82Generalized aminoaciduria (HP:0002909)1.79869657
83Congenital primary aphakia (HP:0007707)1.78380433
84Aplasia/Hypoplasia of the patella (HP:0006498)1.78023548
85Retinal dysplasia (HP:0007973)1.77756330
86Constricted visual fields (HP:0001133)1.77685741
87Gait imbalance (HP:0002141)1.75289491
88Protruding tongue (HP:0010808)1.75203299
89Abnormality of the prostate (HP:0008775)1.73771075
90Exercise intolerance (HP:0003546)1.73709950
91Ketoacidosis (HP:0001993)1.73606775
92Abnormality of T cell physiology (HP:0011840)1.73213189
93Cerebral palsy (HP:0100021)1.69977901
94Patellar aplasia (HP:0006443)1.69787070
95Severe muscular hypotonia (HP:0006829)1.68147839
96Abnormality of urine glucose concentration (HP:0011016)1.67774271
97Glycosuria (HP:0003076)1.67774271
98Bulbous nose (HP:0000414)1.65882510
99Autoimmune thrombocytopenia (HP:0001973)1.65703656
100Hyperalaninemia (HP:0003348)1.64506952

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PINK14.44355238
2ZAK3.65613925
3TLK13.60949588
4TAOK33.06562014
5VRK22.93076020
6ADRBK22.73223610
7FRK2.70230858
8GRK12.51687198
9NUAK12.24514011
10MAP4K22.20862835
11BCKDK1.91827000
12VRK11.91083596
13TXK1.88245214
14MAP4K11.81683006
15BMPR1B1.78744473
16DAPK21.69875564
17ACVR1B1.54984546
18TIE11.54806767
19MAPKAPK31.40227086
20RPS6KA51.36235201
21WNK31.30847232
22GRK61.26787589
23DYRK21.25578771
24WNK41.22855975
25CAMKK21.22657629
26KIT1.21579484
27MAP3K111.18085162
28IKBKB1.17199861
29TNK21.13602089
30MARK31.07755939
31BRSK21.06263320
32SYK1.05550813
33OXSR11.02788291
34TESK21.01135659
35NME10.99756279
36ITK0.98085719
37INSRR0.97433728
38PASK0.96921881
39SRPK10.94889147
40HIPK20.94550802
41STK160.90683467
42OBSCN0.90305403
43PRKCQ0.88801627
44TAF10.88631358
45CDC70.87014795
46MAP2K20.86519326
47NME20.85386412
48MAPK110.84169318
49MAPKAPK50.83978970
50PHKG20.82038242
51PHKG10.82038242
52CAMKK10.78031290
53RPS6KA60.77707508
54MAPK130.76769029
55FES0.75833486
56STK110.74474460
57SIK20.73262552
58DAPK30.72332618
59MAP2K60.72330272
60BTK0.70319361
61ADRBK10.70074340
62ATR0.68763246
63CHEK20.66100831
64CSNK1G30.64896124
65MATK0.62363810
66PIM10.62295511
67TYK20.60703633
68CAMK10.60581200
69STK390.60175990
70KDR0.60037839
71RPS6KL10.58561102
72RPS6KC10.58561102
73LYN0.56951709
74TGFBR10.56226096
75ABL20.55218590
76DAPK10.55035053
77TRIM280.54907131
78CSNK1G20.54613737
79NEK20.52950378
80CSNK1A10.50791747
81TEC0.50030093
82IRAK10.49993098
83CAMK40.49620611
84CDK80.48834495
85CAMK1D0.48493531
86RPS6KB20.46855710
87PRKCI0.45405871
88PIM20.45346442
89PRKCG0.45318161
90PRKAA10.41226230
91MUSK0.41121000
92PIK3CA0.40829552
93PKN10.40448651
94PRKACA0.39745440
95AURKA0.39516711
96PRKAA20.39091250
97NLK0.38435162
98MAP3K70.37194439
99IRAK20.36895949
100MAP3K40.36817949

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.41323928
2Oxidative phosphorylation_Homo sapiens_hsa001903.10955920
3Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.68892214
4Parkinsons disease_Homo sapiens_hsa050122.61752826
5Phototransduction_Homo sapiens_hsa047442.20653735
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.10575503
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.09528630
8Linoleic acid metabolism_Homo sapiens_hsa005912.07230667
9Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.99717742
10Systemic lupus erythematosus_Homo sapiens_hsa053221.99226964
11RNA polymerase_Homo sapiens_hsa030201.97655466
12Sulfur relay system_Homo sapiens_hsa041221.96004571
13Selenocompound metabolism_Homo sapiens_hsa004501.83550321
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.82847582
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.80873977
16Homologous recombination_Homo sapiens_hsa034401.78131743
17Primary immunodeficiency_Homo sapiens_hsa053401.75478401
18Fanconi anemia pathway_Homo sapiens_hsa034601.71765507
19Nitrogen metabolism_Homo sapiens_hsa009101.70466967
20Asthma_Homo sapiens_hsa053101.68037639
21Tryptophan metabolism_Homo sapiens_hsa003801.64939488
22Huntingtons disease_Homo sapiens_hsa050161.62131259
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.55249344
24Base excision repair_Homo sapiens_hsa034101.53523730
25Alzheimers disease_Homo sapiens_hsa050101.53448546
26Non-homologous end-joining_Homo sapiens_hsa034501.50442409
27One carbon pool by folate_Homo sapiens_hsa006701.50415941
28Butanoate metabolism_Homo sapiens_hsa006501.46117932
29Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.42503685
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.38319089
31RNA degradation_Homo sapiens_hsa030181.34175263
32Pyrimidine metabolism_Homo sapiens_hsa002401.30436896
33Cardiac muscle contraction_Homo sapiens_hsa042601.29616269
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.28310033
35Allograft rejection_Homo sapiens_hsa053301.27889909
36Ether lipid metabolism_Homo sapiens_hsa005651.27222485
37Type I diabetes mellitus_Homo sapiens_hsa049401.26833996
38Peroxisome_Homo sapiens_hsa041461.26416942
39Caffeine metabolism_Homo sapiens_hsa002321.25806579
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.25431997
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.24077682
42Autoimmune thyroid disease_Homo sapiens_hsa053201.23208107
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23107119
44DNA replication_Homo sapiens_hsa030301.21295968
45Graft-versus-host disease_Homo sapiens_hsa053321.17315452
46Folate biosynthesis_Homo sapiens_hsa007901.13233373
47Basal transcription factors_Homo sapiens_hsa030221.10193162
48Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.04344504
49Arachidonic acid metabolism_Homo sapiens_hsa005901.03564178
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02755925
51Primary bile acid biosynthesis_Homo sapiens_hsa001200.99574354
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.96980012
53Regulation of autophagy_Homo sapiens_hsa041400.95929318
54Chemical carcinogenesis_Homo sapiens_hsa052040.95413955
55Steroid hormone biosynthesis_Homo sapiens_hsa001400.93014280
56Proteasome_Homo sapiens_hsa030500.92950379
57Purine metabolism_Homo sapiens_hsa002300.92804779
58Protein export_Homo sapiens_hsa030600.92529591
59Fatty acid degradation_Homo sapiens_hsa000710.90783701
60Nucleotide excision repair_Homo sapiens_hsa034200.90653208
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.88967344
62Metabolic pathways_Homo sapiens_hsa011000.82272098
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82190301
64Alcoholism_Homo sapiens_hsa050340.80066602
65Mismatch repair_Homo sapiens_hsa034300.78554979
66Retinol metabolism_Homo sapiens_hsa008300.76297033
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.75411742
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.75380519
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68827167
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67598513
71Propanoate metabolism_Homo sapiens_hsa006400.66977233
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66027016
73Ovarian steroidogenesis_Homo sapiens_hsa049130.65047924
74Cysteine and methionine metabolism_Homo sapiens_hsa002700.62200812
75Collecting duct acid secretion_Homo sapiens_hsa049660.56686549
76Staphylococcus aureus infection_Homo sapiens_hsa051500.55472473
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.53674043
78Rheumatoid arthritis_Homo sapiens_hsa053230.51907761
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51302671
80Spliceosome_Homo sapiens_hsa030400.50157525
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49284877
82Fatty acid elongation_Homo sapiens_hsa000620.48702891
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.45959773
84ABC transporters_Homo sapiens_hsa020100.45427653
85beta-Alanine metabolism_Homo sapiens_hsa004100.44582955
86Drug metabolism - other enzymes_Homo sapiens_hsa009830.43938623
87Fat digestion and absorption_Homo sapiens_hsa049750.43514585
88Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43220962
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42682490
90Pyruvate metabolism_Homo sapiens_hsa006200.41112526
91Sulfur metabolism_Homo sapiens_hsa009200.38182919
92Histidine metabolism_Homo sapiens_hsa003400.35929450
93Hematopoietic cell lineage_Homo sapiens_hsa046400.35625267
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35475075
95Antigen processing and presentation_Homo sapiens_hsa046120.35115097
96Fatty acid metabolism_Homo sapiens_hsa012120.34722544
97RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34549442
98Olfactory transduction_Homo sapiens_hsa047400.32885423
99Vitamin digestion and absorption_Homo sapiens_hsa049770.31881765
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29897401

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »