ZNF709

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.03083013
2nucleobase catabolic process (GO:0046113)4.33601274
3retinal ganglion cell axon guidance (GO:0031290)3.99815345
4intraciliary transport (GO:0042073)3.98842156
5protein K11-linked deubiquitination (GO:0035871)3.97906687
6response to pheromone (GO:0019236)3.96101445
7protein polyglutamylation (GO:0018095)3.90882246
8regulation of cilium movement (GO:0003352)3.64226997
9gamma-aminobutyric acid transport (GO:0015812)3.62094369
10presynaptic membrane assembly (GO:0097105)3.56563619
11replication fork processing (GO:0031297)3.50778573
12DNA double-strand break processing (GO:0000729)3.38614840
13epithelial cilium movement (GO:0003351)3.30723470
14cilium organization (GO:0044782)3.27526468
15cilium assembly (GO:0042384)3.26660594
16histone H2A acetylation (GO:0043968)3.24049408
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.22339269
18axonal fasciculation (GO:0007413)3.18395633
19DNA integration (GO:0015074)3.13649810
20synapsis (GO:0007129)3.12627329
21neuronal action potential propagation (GO:0019227)3.11820876
22righting reflex (GO:0060013)3.10128773
23protein localization to cilium (GO:0061512)3.06911325
24neuron recognition (GO:0008038)3.04226762
25cilium morphogenesis (GO:0060271)3.01111729
26cilium movement (GO:0003341)2.99518680
27negative regulation of translation, ncRNA-mediated (GO:0040033)2.99477018
28regulation of translation, ncRNA-mediated (GO:0045974)2.99477018
29negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.99477018
30glycosphingolipid biosynthetic process (GO:0006688)2.98676202
31oxidative demethylation (GO:0070989)2.97689183
32cerebral cortex radially oriented cell migration (GO:0021799)2.96170549
33head development (GO:0060322)2.95622284
34presynaptic membrane organization (GO:0097090)2.93808815
35positive regulation of mitochondrial fission (GO:0090141)2.93551813
36behavioral response to ethanol (GO:0048149)2.93141515
37acrosome reaction (GO:0007340)2.91645963
38regulation of collateral sprouting (GO:0048670)2.89450854
39negative regulation of axon guidance (GO:1902668)2.89440831
40negative regulation of DNA recombination (GO:0045910)2.88806630
41maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.87681695
42centriole replication (GO:0007099)2.85935071
43regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.85147897
44neural tube formation (GO:0001841)2.85099352
45neuron cell-cell adhesion (GO:0007158)2.82318303
46reflex (GO:0060004)2.82272360
47axoneme assembly (GO:0035082)2.79268302
48neurotransmitter-gated ion channel clustering (GO:0072578)2.78383593
49olfactory bulb development (GO:0021772)2.78145730
50nonmotile primary cilium assembly (GO:0035058)2.76215880
51photoreceptor cell maintenance (GO:0045494)2.75201071
52auditory behavior (GO:0031223)2.73692681
53negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.72843837
54postsynaptic membrane organization (GO:0001941)2.71466581
55cullin deneddylation (GO:0010388)2.70911689
56microtubule depolymerization (GO:0007019)2.69464637
57regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68052528
58regulation of telomere maintenance (GO:0032204)2.66067026
59negative regulation of axon extension involved in axon guidance (GO:0048843)2.64989916
60negative regulation of cytosolic calcium ion concentration (GO:0051481)2.64634730
61calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.63631189
62limb bud formation (GO:0060174)2.63393048
63detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.63158208
64cell migration in hindbrain (GO:0021535)2.61933832
65cellular component assembly involved in morphogenesis (GO:0010927)2.61550005
66negative regulation of dendrite development (GO:2000171)2.61051633
67DNA ligation (GO:0006266)2.59425005
68cilium or flagellum-dependent cell motility (GO:0001539)2.56325561
69vocalization behavior (GO:0071625)2.55333265
70startle response (GO:0001964)2.52279545
71positive regulation of amino acid transport (GO:0051957)2.51870088
72resolution of meiotic recombination intermediates (GO:0000712)2.51637843
73striatum development (GO:0021756)2.50588672
74negative regulation of DNA-dependent DNA replication (GO:2000104)2.48510165
75behavioral response to nicotine (GO:0035095)2.47837898
76transmission of nerve impulse (GO:0019226)2.47114392
77DNA demethylation (GO:0080111)2.46703029
78regulation of Rac GTPase activity (GO:0032314)2.46526941
79spermatid nucleus differentiation (GO:0007289)2.45410709
80glycerophospholipid catabolic process (GO:0046475)2.44107116
81protein localization to peroxisome (GO:0072662)2.43575934
82protein targeting to peroxisome (GO:0006625)2.43575934
83establishment of protein localization to peroxisome (GO:0072663)2.43575934
84regulation of heat generation (GO:0031650)2.43480785
85protein import into peroxisome matrix (GO:0016558)2.42364354
86somite development (GO:0061053)2.41306581
87cell wall macromolecule catabolic process (GO:0016998)2.41114408
88mechanosensory behavior (GO:0007638)2.38822282
89synapse assembly (GO:0007416)2.38553680
90hindbrain development (GO:0030902)2.37338616
91regulation of microtubule-based movement (GO:0060632)2.36531696
92central nervous system projection neuron axonogenesis (GO:0021952)2.36059891
93regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.35658940
94regulation of mitotic spindle checkpoint (GO:1903504)2.35658940
95regulation of dendritic spine development (GO:0060998)2.35294900
96regulation of sarcomere organization (GO:0060297)2.34770570
97negative regulation of transcription regulatory region DNA binding (GO:2000678)2.34336889
98respiratory chain complex IV assembly (GO:0008535)2.32117063
99positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.30986545
100piRNA metabolic process (GO:0034587)2.30604952

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* ZNF274_21170338_ChIP-Seq_K562_Hela3.35402373
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.34654700
3GBX2_23144817_ChIP-Seq_PC3_Human3.29409630
4IGF1R_20145208_ChIP-Seq_DFB_Human3.11495153
5ZFP57_27257070_Chip-Seq_ESCs_Mouse3.05883134
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.93559286
7* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.92927539
8TAF15_26573619_Chip-Seq_HEK293_Human2.83137829
9FUS_26573619_Chip-Seq_HEK293_Human2.68008270
10VDR_22108803_ChIP-Seq_LS180_Human2.56423213
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.55233659
12EWS_26573619_Chip-Seq_HEK293_Human2.30174006
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.23985334
14P300_19829295_ChIP-Seq_ESCs_Human2.15126840
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.05218689
16TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97923067
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.94731586
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.89555774
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.89034169
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.86748786
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.86137608
22HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84328944
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.82511978
24SMAD4_21799915_ChIP-Seq_A2780_Human1.82412537
25* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82287607
26PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.79067816
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.77547723
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.77349625
29SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.76459095
30KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.71662299
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.70414396
32MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.68730163
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.67100625
34OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.60915075
35EST1_17652178_ChIP-ChIP_JURKAT_Human1.56983170
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.56647705
37* STAT3_23295773_ChIP-Seq_U87_Human1.53570027
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51637403
39IRF1_19129219_ChIP-ChIP_H3396_Human1.51403979
40PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51151998
41BCAT_22108803_ChIP-Seq_LS180_Human1.49821110
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.45334634
43EZH2_22144423_ChIP-Seq_EOC_Human1.45222524
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.43168723
45TCF4_23295773_ChIP-Seq_U87_Human1.41991561
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41921807
47* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41749977
48* CBP_20019798_ChIP-Seq_JUKART_Human1.41749977
49* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41713863
50AR_25329375_ChIP-Seq_VCAP_Human1.41456849
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.41390806
52ER_23166858_ChIP-Seq_MCF-7_Human1.40687250
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38835175
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36155440
55RNF2_27304074_Chip-Seq_NSC_Mouse1.35553603
56POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34111511
57TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34111511
58NR3C1_21868756_ChIP-Seq_MCF10A_Human1.33891817
59PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32168841
60E2F4_17652178_ChIP-ChIP_JURKAT_Human1.30252938
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28421166
62NANOG_18555785_Chip-Seq_ESCs_Mouse1.28274134
63GABP_17652178_ChIP-ChIP_JURKAT_Human1.26716222
64EZH2_27294783_Chip-Seq_NPCs_Mouse1.25523673
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24519534
66TCF4_22108803_ChIP-Seq_LS180_Human1.23047815
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22347978
68RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21158860
69REST_21632747_ChIP-Seq_MESCs_Mouse1.20353078
70RUNX2_22187159_ChIP-Seq_PCA_Human1.20350327
71ELK1_19687146_ChIP-ChIP_HELA_Human1.17825095
72KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16685345
73SOX2_19829295_ChIP-Seq_ESCs_Human1.16404557
74NANOG_19829295_ChIP-Seq_ESCs_Human1.16404557
75NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.14294721
76TP53_22573176_ChIP-Seq_HFKS_Human1.13891905
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.13011368
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11195437
79MYC_18940864_ChIP-ChIP_HL60_Human1.10628696
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10176560
81* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10161393
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09555288
83CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07723030
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07350542
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07279672
86PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06674437
87NFE2_27457419_Chip-Seq_LIVER_Mouse1.06657370
88KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.04103425
89BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03513502
90TAL1_26923725_Chip-Seq_HPCs_Mouse1.03089160
91TP63_19390658_ChIP-ChIP_HaCaT_Human1.02562946
92SOX2_21211035_ChIP-Seq_LN229_Gbm1.02369538
93P53_22387025_ChIP-Seq_ESCs_Mouse1.00860506
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.00139716
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.99535797
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98768267
97JUN_21703547_ChIP-Seq_K562_Human0.98228902
98CRX_20693478_ChIP-Seq_RETINA_Mouse0.98187527
99VDR_23849224_ChIP-Seq_CD4+_Human0.97612943
100NOTCH1_21737748_ChIP-Seq_TLL_Human0.97180133

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.13777478
2MP0002102_abnormal_ear_morphology3.11577346
3MP0001529_abnormal_vocalization2.92831629
4MP0003880_abnormal_central_pattern2.82827638
5MP0000569_abnormal_digit_pigmentation2.76366405
6MP0003122_maternal_imprinting2.52637386
7MP0003787_abnormal_imprinting2.48678847
8MP0001984_abnormal_olfaction2.46140575
9MP0004270_analgesia2.39915275
10MP0003121_genomic_imprinting2.36187900
11MP0000778_abnormal_nervous_system2.10736835
12MP0004859_abnormal_synaptic_plasticity2.09098105
13MP0005551_abnormal_eye_electrophysiolog2.05400696
14MP0009046_muscle_twitch1.97050088
15MP0005084_abnormal_gallbladder_morpholo1.96306500
16MP0008058_abnormal_DNA_repair1.92206492
17MP0002938_white_spotting1.82063387
18MP0008057_abnormal_DNA_replication1.81685696
19MP0001968_abnormal_touch/_nociception1.75225554
20MP0005499_abnormal_olfactory_system1.72314681
21MP0005394_taste/olfaction_phenotype1.72314681
22MP0008789_abnormal_olfactory_epithelium1.69591669
23MP0000631_abnormal_neuroendocrine_gland1.67905574
24MP0006292_abnormal_olfactory_placode1.64869899
25MP0009745_abnormal_behavioral_response1.63309668
26MP0005253_abnormal_eye_physiology1.58510842
27MP0001293_anophthalmia1.57680261
28MP0001486_abnormal_startle_reflex1.57154737
29MP0006072_abnormal_retinal_apoptosis1.56408845
30MP0003635_abnormal_synaptic_transmissio1.49794108
31MP0002735_abnormal_chemical_nociception1.47125597
32MP0003718_maternal_effect1.46708109
33MP0005248_abnormal_Harderian_gland1.44590999
34MP0002734_abnormal_mechanical_nocicepti1.44432116
35MP0001986_abnormal_taste_sensitivity1.41313451
36MP0010094_abnormal_chromosome_stability1.40407973
37MP0004142_abnormal_muscle_tone1.38861378
38MP0000516_abnormal_urinary_system1.38518100
39MP0005367_renal/urinary_system_phenotyp1.38518100
40MP0002736_abnormal_nociception_after1.38514546
41MP0005423_abnormal_somatic_nervous1.37107937
42MP0002837_dystrophic_cardiac_calcinosis1.37093750
43MP0002638_abnormal_pupillary_reflex1.35052017
44MP0004924_abnormal_behavior1.34564616
45MP0005386_behavior/neurological_phenoty1.34564616
46MP0002063_abnormal_learning/memory/cond1.33788410
47MP0004133_heterotaxia1.33629785
48MP0000427_abnormal_hair_cycle1.30966564
49MP0002928_abnormal_bile_duct1.30672961
50MP0002272_abnormal_nervous_system1.28148505
51MP0002233_abnormal_nose_morphology1.27610362
52MP0002572_abnormal_emotion/affect_behav1.26353260
53MP0008995_early_reproductive_senescence1.26097455
54MP0002751_abnormal_autonomic_nervous1.24894922
55MP0006276_abnormal_autonomic_nervous1.22393471
56MP0002557_abnormal_social/conspecific_i1.21582610
57MP0003786_premature_aging1.16075135
58MP0002822_catalepsy1.15582734
59MP0003195_calcinosis1.11538456
60MP0003937_abnormal_limbs/digits/tail_de1.09619502
61MP0002184_abnormal_innervation1.08141767
62MP0002064_seizures1.06936478
63MP0003698_abnormal_male_reproductive1.06719724
64MP0004147_increased_porphyrin_level1.06580417
65MP0005646_abnormal_pituitary_gland1.05555298
66MP0000955_abnormal_spinal_cord1.00978309
67MP0002234_abnormal_pharynx_morphology1.00221470
68MP0001501_abnormal_sleep_pattern0.99583293
69MP0001929_abnormal_gametogenesis0.99550092
70MP0004811_abnormal_neuron_physiology0.99472677
71MP0001485_abnormal_pinna_reflex0.98967079
72MP0000647_abnormal_sebaceous_gland0.97778007
73MP0003137_abnormal_impulse_conducting0.97486982
74MP0002752_abnormal_somatic_nervous0.95397609
75MP0005391_vision/eye_phenotype0.94552679
76MP0003861_abnormal_nervous_system0.94293225
77MP0002882_abnormal_neuron_morphology0.93321505
78MP0001177_atelectasis0.93067474
79MP0002067_abnormal_sensory_capabilities0.92621937
80MP0002152_abnormal_brain_morphology0.91353984
81MP0005187_abnormal_penis_morphology0.90744826
82MP0003119_abnormal_digestive_system0.87304329
83MP0002090_abnormal_vision0.86576754
84MP0004043_abnormal_pH_regulation0.85633088
85MP0005195_abnormal_posterior_eye0.85041854
86MP0004215_abnormal_myocardial_fiber0.85005067
87MP0010678_abnormal_skin_adnexa0.83659541
88MP0001905_abnormal_dopamine_level0.83480513
89MP0002160_abnormal_reproductive_system0.82811627
90MP0008872_abnormal_physiological_respon0.78045913
91MP0003755_abnormal_palate_morphology0.77638907
92MP0010234_abnormal_vibrissa_follicle0.76921184
93MP0009697_abnormal_copulation0.76549347
94MP0000653_abnormal_sex_gland0.74812088
95MP0005410_abnormal_fertilization0.74536936
96MP0002210_abnormal_sex_determination0.73712957
97MP0000383_abnormal_hair_follicle0.73689567
98MP0001970_abnormal_pain_threshold0.73603409
99MP0005395_other_phenotype0.72398511
100MP0002876_abnormal_thyroid_physiology0.71887826

Predicted human phenotypes

RankGene SetZ-score
1Chronic hepatic failure (HP:0100626)4.21471024
2Pancreatic cysts (HP:0001737)4.00933656
3Pancreatic fibrosis (HP:0100732)3.76950882
4Abnormality of midbrain morphology (HP:0002418)3.65217296
5Molar tooth sign on MRI (HP:0002419)3.65217296
6True hermaphroditism (HP:0010459)3.56534528
7Nephronophthisis (HP:0000090)3.42359330
8Medial flaring of the eyebrow (HP:0010747)3.33341418
9Volvulus (HP:0002580)3.07232810
10Gait imbalance (HP:0002141)3.04808837
11Tubulointerstitial nephritis (HP:0001970)2.99291136
12Absent speech (HP:0001344)2.99216244
13Congenital primary aphakia (HP:0007707)2.96026326
14Genital tract atresia (HP:0001827)2.90668120
15Abnormality of the renal medulla (HP:0100957)2.90648135
16Abnormality of the labia minora (HP:0012880)2.88092630
17Progressive inability to walk (HP:0002505)2.81668934
18Nephrogenic diabetes insipidus (HP:0009806)2.79758209
19Vaginal atresia (HP:0000148)2.79659415
20Abnormality of the renal cortex (HP:0011035)2.74374180
21Renal cortical cysts (HP:0000803)2.70191616
22Methylmalonic acidemia (HP:0002912)2.58947540
23Aplasia/Hypoplasia of the tongue (HP:0010295)2.55624755
24Type II lissencephaly (HP:0007260)2.50734491
25Neoplasm of the oral cavity (HP:0100649)2.48351162
26Narrow forehead (HP:0000341)2.47308059
27Abnormal biliary tract physiology (HP:0012439)2.45681949
28Bile duct proliferation (HP:0001408)2.45681949
29Lissencephaly (HP:0001339)2.42923760
30Cystic liver disease (HP:0006706)2.38800591
31Large for gestational age (HP:0001520)2.35135980
32Hyperventilation (HP:0002883)2.35037617
33Occipital encephalocele (HP:0002085)2.32902610
34Hip dysplasia (HP:0001385)2.29494449
35Postaxial foot polydactyly (HP:0001830)2.24980780
36Intestinal atresia (HP:0011100)2.21558836
37Postaxial hand polydactyly (HP:0001162)2.20663567
38Amyotrophic lateral sclerosis (HP:0007354)2.20317565
39Retinal dysplasia (HP:0007973)2.19788142
40Osteomalacia (HP:0002749)2.19247225
41Exotropia (HP:0000577)2.18589934
42Drooling (HP:0002307)2.13039495
43Abnormality of permanent molar morphology (HP:0011071)2.12107609
44Abnormality of the dental root (HP:0006486)2.12107609
45Taurodontia (HP:0000679)2.12107609
46Methylmalonic aciduria (HP:0012120)2.11112390
47Abnormality of renal resorption (HP:0011038)2.10396487
48Poor coordination (HP:0002370)2.05977908
49Inability to walk (HP:0002540)2.05668483
50Preaxial hand polydactyly (HP:0001177)2.03571324
51Hypothermia (HP:0002045)2.03365951
52Proximal tubulopathy (HP:0000114)2.02995887
53Abnormality of vitamin metabolism (HP:0100508)2.00537585
54Aplasia/Hypoplasia of the tibia (HP:0005772)1.99377396
55Abnormality of vitamin B metabolism (HP:0004340)1.99051358
56Anencephaly (HP:0002323)1.98712648
57Focal motor seizures (HP:0011153)1.97868897
58Aplasia/Hypoplasia of the lens (HP:0008063)1.97270019
59Prominent nasal bridge (HP:0000426)1.95160682
60Optic nerve coloboma (HP:0000588)1.94387355
61Abnormality of the dental pulp (HP:0006479)1.94082256
62Colon cancer (HP:0003003)1.91853049
63Highly arched eyebrow (HP:0002553)1.91846555
64Brushfield spots (HP:0001088)1.91819333
65Excessive salivation (HP:0003781)1.91075790
66Abnormality of molar (HP:0011077)1.90920109
67Abnormality of molar morphology (HP:0011070)1.90920109
68Protruding tongue (HP:0010808)1.90118848
69Abnormal lung lobation (HP:0002101)1.87078872
70Sclerocornea (HP:0000647)1.86513478
71Polyphagia (HP:0002591)1.84606934
72Abnormal ciliary motility (HP:0012262)1.83435561
73Congenital stationary night blindness (HP:0007642)1.83387934
74Optic nerve hypoplasia (HP:0000609)1.81656984
75Tubulointerstitial abnormality (HP:0001969)1.81526133
76Oligodactyly (hands) (HP:0001180)1.81299646
77Broad-based gait (HP:0002136)1.80095060
78Progressive cerebellar ataxia (HP:0002073)1.79419628
79Cupped ear (HP:0000378)1.77662018
80Febrile seizures (HP:0002373)1.76896237
81Short tibia (HP:0005736)1.76748654
82Oculomotor apraxia (HP:0000657)1.76745831
83Limb dystonia (HP:0002451)1.76708029
84Absent/shortened dynein arms (HP:0200106)1.76070480
85Dynein arm defect of respiratory motile cilia (HP:0012255)1.76070480
86Furrowed tongue (HP:0000221)1.75937907
87Poor suck (HP:0002033)1.75413243
88Widely spaced teeth (HP:0000687)1.75166276
89Aplasia/Hypoplasia of the uvula (HP:0010293)1.75135752
90Renal hypoplasia (HP:0000089)1.74974061
91Tubular atrophy (HP:0000092)1.74116203
92Abnormality of the vitamin B12 metabolism (HP:0004341)1.73645770
93Pachygyria (HP:0001302)1.73588813
94Midline defect of the nose (HP:0004122)1.73314050
95Meckel diverticulum (HP:0002245)1.72390425
96Cerebellar dysplasia (HP:0007033)1.72243650
97Abnormality of the ileum (HP:0001549)1.70354083
98Pendular nystagmus (HP:0012043)1.69950102
99Congenital hepatic fibrosis (HP:0002612)1.67837654
100Stomach cancer (HP:0012126)1.66824687

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK34.10328956
2FRK4.06876913
3MAP3K42.77746764
4CASK2.66698893
5EPHA42.52166085
6TRIM282.49809732
7MARK12.41700179
8PNCK2.34929652
9TNIK2.34893759
10BMPR1B2.22464806
11MAP2K72.21012716
12BCR2.19038977
13BRD42.17677312
14MAPK132.15287454
15MKNK22.14801984
16MAP4K22.13146935
17ERBB31.92114050
18EIF2AK31.78751330
19BRSK21.77928153
20SRPK11.64917187
21PLK41.63178727
22FGFR21.59945662
23CCNB11.51069202
24ACVR1B1.47130165
25WEE11.41632939
26MINK11.41062666
27PLK31.40811816
28MKNK11.39706483
29CSNK1G11.27695204
30CSNK1G21.26827713
31NUAK11.23348140
32TIE11.21316581
33CSNK1G31.19474218
34DYRK21.16731666
35PINK11.13413891
36CAMKK21.12051712
37ZAK1.11912577
38TSSK61.11584053
39INSRR1.10262424
40CSNK1A1L1.08823444
41STK391.05306599
42ADRBK20.99979728
43PAK30.99579028
44GRK10.96144231
45NTRK30.92806933
46PRKCG0.91455337
47MARK30.88806083
48PLK10.87688370
49PLK20.85007553
50STK30.84581827
51NTRK20.84069489
52PRKCE0.83812339
53OXSR10.82970345
54STK160.81346790
55TTK0.81149172
56STK38L0.78374328
57TGFBR10.75619330
58DYRK1A0.74691915
59EPHA30.70258083
60KSR10.69092382
61TAOK30.66820080
62VRK10.66171306
63DYRK30.62503741
64ATR0.61155092
65CDK50.59678234
66STK110.58427987
67MAP2K40.57793283
68ATM0.56063296
69UHMK10.52771806
70PKN10.52377198
71PRKCZ0.50703882
72CAMK2A0.49832682
73CAMK1G0.48984592
74DAPK20.48127573
75TAOK10.47758433
76CSNK1D0.46005110
77CSNK1A10.45903321
78CDK140.43453555
79BUB10.42880790
80EIF2AK20.41535836
81CDK180.39779504
82STK380.39389630
83FLT30.38557498
84WNK40.38239955
85CDK90.35648987
86OBSCN0.35489928
87ADRBK10.34778537
88PHKG10.34667442
89PHKG20.34667442
90CSNK1E0.34494940
91PRKACB0.33758228
92CDK150.33402735
93CDC70.33072962
94PRKCI0.31697628
95PRKAA10.30789401
96CDK10.30355914
97RPS6KA40.30170558
98PRKACA0.29668742
99BRSK10.28892348
100FGFR10.28691520

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.88079023
2Phototransduction_Homo sapiens_hsa047442.85251781
3Protein export_Homo sapiens_hsa030602.70704928
4Non-homologous end-joining_Homo sapiens_hsa034502.67659843
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.66646319
6Selenocompound metabolism_Homo sapiens_hsa004502.60660370
7Fanconi anemia pathway_Homo sapiens_hsa034602.47845417
8Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.41109724
9Nicotine addiction_Homo sapiens_hsa050332.38499385
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.27740450
11Butanoate metabolism_Homo sapiens_hsa006502.25208058
12Propanoate metabolism_Homo sapiens_hsa006402.07003625
13Nitrogen metabolism_Homo sapiens_hsa009101.77752700
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.74008599
15Ether lipid metabolism_Homo sapiens_hsa005651.62492994
16Taste transduction_Homo sapiens_hsa047421.54969514
17GABAergic synapse_Homo sapiens_hsa047271.54389087
18Homologous recombination_Homo sapiens_hsa034401.53966151
19RNA degradation_Homo sapiens_hsa030181.52230572
20Basal transcription factors_Homo sapiens_hsa030221.49230426
21Circadian rhythm_Homo sapiens_hsa047101.47698050
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.46219762
23Circadian entrainment_Homo sapiens_hsa047131.43294593
24Vitamin B6 metabolism_Homo sapiens_hsa007501.41556102
25Steroid biosynthesis_Homo sapiens_hsa001001.41043533
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.38441496
27Morphine addiction_Homo sapiens_hsa050321.34713405
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.34613968
29Dopaminergic synapse_Homo sapiens_hsa047281.33226727
30Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.24180786
31Peroxisome_Homo sapiens_hsa041461.23723810
32Hedgehog signaling pathway_Homo sapiens_hsa043401.20595644
33Linoleic acid metabolism_Homo sapiens_hsa005911.19086178
34Tryptophan metabolism_Homo sapiens_hsa003801.17497312
35Oocyte meiosis_Homo sapiens_hsa041141.11509615
36Sulfur metabolism_Homo sapiens_hsa009201.08962587
37Glutamatergic synapse_Homo sapiens_hsa047241.07238540
38Folate biosynthesis_Homo sapiens_hsa007901.05110207
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03397400
40Insulin secretion_Homo sapiens_hsa049111.03387232
41Regulation of autophagy_Homo sapiens_hsa041401.02812330
42Caffeine metabolism_Homo sapiens_hsa002320.97943173
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.96120759
44Olfactory transduction_Homo sapiens_hsa047400.94632937
45Synaptic vesicle cycle_Homo sapiens_hsa047210.94507376
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.93935663
47Amphetamine addiction_Homo sapiens_hsa050310.91948547
48Cocaine addiction_Homo sapiens_hsa050300.91666965
49Base excision repair_Homo sapiens_hsa034100.90126939
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.89409839
51Mismatch repair_Homo sapiens_hsa034300.89365641
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.88181976
53p53 signaling pathway_Homo sapiens_hsa041150.87886306
54beta-Alanine metabolism_Homo sapiens_hsa004100.86873437
55Long-term depression_Homo sapiens_hsa047300.83502559
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79696106
57Maturity onset diabetes of the young_Homo sapiens_hsa049500.78471945
58RNA transport_Homo sapiens_hsa030130.78448779
59Collecting duct acid secretion_Homo sapiens_hsa049660.77934122
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.74126613
61Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72761967
62ABC transporters_Homo sapiens_hsa020100.72520663
63Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.71899758
64Lysine degradation_Homo sapiens_hsa003100.71009292
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.67862708
66Sphingolipid metabolism_Homo sapiens_hsa006000.67831759
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67539031
68Purine metabolism_Homo sapiens_hsa002300.66100071
69Salivary secretion_Homo sapiens_hsa049700.63832151
70Chemical carcinogenesis_Homo sapiens_hsa052040.62874130
71Fatty acid elongation_Homo sapiens_hsa000620.62598722
72Oxidative phosphorylation_Homo sapiens_hsa001900.61810105
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.60394149
74Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60191627
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59390071
76Hippo signaling pathway_Homo sapiens_hsa043900.58962814
77Serotonergic synapse_Homo sapiens_hsa047260.58254417
78mRNA surveillance pathway_Homo sapiens_hsa030150.57581145
79Cell cycle_Homo sapiens_hsa041100.57066214
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55950216
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.55691217
82Metabolic pathways_Homo sapiens_hsa011000.55552485
83Axon guidance_Homo sapiens_hsa043600.55113298
84RNA polymerase_Homo sapiens_hsa030200.55004718
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.52308947
86Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52293196
87Renin secretion_Homo sapiens_hsa049240.51981665
88Parkinsons disease_Homo sapiens_hsa050120.51321734
89Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50752298
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50153535
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.49548944
92Basal cell carcinoma_Homo sapiens_hsa052170.48915980
93Huntingtons disease_Homo sapiens_hsa050160.47761860
94Inositol phosphate metabolism_Homo sapiens_hsa005620.46434699
95Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45757918
96TGF-beta signaling pathway_Homo sapiens_hsa043500.44654180
97Fatty acid metabolism_Homo sapiens_hsa012120.44216061
98Retinol metabolism_Homo sapiens_hsa008300.44133830
99Calcium signaling pathway_Homo sapiens_hsa040200.43472856
100Cholinergic synapse_Homo sapiens_hsa047250.40048000

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »