ZNF692

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of erythrocyte differentiation (GO:0045647)5.91456388
2mannose metabolic process (GO:0006013)5.88869961
3histone H4 deacetylation (GO:0070933)5.01203641
4regulation of ARF GTPase activity (GO:0032312)4.74861806
5mitochondrion transport along microtubule (GO:0047497)4.47468412
6establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.47468412
7establishment of mitochondrion localization (GO:0051654)4.34272882
8regulation of translational fidelity (GO:0006450)4.31850058
9regulation of histone H3-K27 methylation (GO:0061085)4.21439310
10proline biosynthetic process (GO:0006561)4.13936266
11negative regulation of amyloid precursor protein catabolic process (GO:1902992)4.10891078
12histone H3 deacetylation (GO:0070932)4.08736263
13GDP-mannose metabolic process (GO:0019673)4.05733436
14poly(A)+ mRNA export from nucleus (GO:0016973)3.93762082
15semaphorin-plexin signaling pathway (GO:0071526)3.84809994
16snRNA metabolic process (GO:0016073)3.80474560
17regulation of chromatin binding (GO:0035561)3.78933915
18negative regulation of cell size (GO:0045792)3.74443634
19regulation of hydrogen peroxide metabolic process (GO:0010310)3.72445684
20DNA topological change (GO:0006265)3.65334102
21protein retention in ER lumen (GO:0006621)3.62087562
22Golgi transport vesicle coating (GO:0048200)3.61703814
23COPI coating of Golgi vesicle (GO:0048205)3.61703814
24retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.60604444
25snRNA processing (GO:0016180)3.59049813
26histone H3-K9 demethylation (GO:0033169)3.58783707
27proline metabolic process (GO:0006560)3.55298524
28histone H3-K4 trimethylation (GO:0080182)3.43572440
29positive regulation of CREB transcription factor activity (GO:0032793)3.39032393
30regulation of cholesterol metabolic process (GO:0090181)3.34991797
31maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.27551203
32cell migration in hindbrain (GO:0021535)3.25919914
33regulation of histone H3-K4 methylation (GO:0051569)3.25699990
34Arp2/3 complex-mediated actin nucleation (GO:0034314)3.19937249
35synaptic vesicle exocytosis (GO:0016079)3.18223802
36stress granule assembly (GO:0034063)3.16276122
37gas transport (GO:0015669)3.15844620
38positive regulation of histone deacetylation (GO:0031065)3.10152864
39cell-cell junction maintenance (GO:0045217)3.09883454
40oxygen transport (GO:0015671)3.07330960
41positive regulation of synapse maturation (GO:0090129)3.07203465
42positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.06327533
43granulocyte differentiation (GO:0030851)3.05815558
44intracellular estrogen receptor signaling pathway (GO:0030520)3.05295377
45protein kinase C signaling (GO:0070528)3.01003309
46regulation of ARF protein signal transduction (GO:0032012)3.00983633
47nucleosome disassembly (GO:0006337)3.00024121
48protein-DNA complex disassembly (GO:0032986)3.00024121
49mucosal-associated lymphoid tissue development (GO:0048537)2.94330380
50Peyers patch development (GO:0048541)2.94330380
51regulation of cholesterol biosynthetic process (GO:0045540)2.94142368
52negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.92757871
53protoporphyrinogen IX metabolic process (GO:0046501)2.85934257
54histone H3-K9 modification (GO:0061647)2.85322083
55positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.85250955
56synaptic vesicle docking involved in exocytosis (GO:0016081)2.85152311
57histone deubiquitination (GO:0016578)2.84725263
58retrograde transport, endosome to Golgi (GO:0042147)2.83000244
59UV protection (GO:0009650)2.82306829
60regulation of RNA export from nucleus (GO:0046831)2.81291963
61peptidyl-tyrosine autophosphorylation (GO:0038083)2.81058600
62positive regulation of protein kinase C signaling (GO:0090037)2.80002324
63phosphatidylglycerol biosynthetic process (GO:0006655)2.79874320
64activation of Rac GTPase activity (GO:0032863)2.79630844
65histone H3-K4 methylation (GO:0051568)2.78475210
66negative regulation of DNA-templated transcription, elongation (GO:0032785)2.78464150
67regulation of nucleobase-containing compound transport (GO:0032239)2.75827810
68thymic T cell selection (GO:0045061)2.74607386
69histone deacetylation (GO:0016575)2.74285368
70modulation by virus of host process (GO:0019054)2.73762164
71protein insertion into membrane (GO:0051205)2.73575513
72viral transcription (GO:0019083)2.72167528
73erythrocyte development (GO:0048821)2.71948168
74creatine metabolic process (GO:0006600)2.71069284
75negative regulation of fatty acid biosynthetic process (GO:0045717)2.67040551
76histone H3-K9 methylation (GO:0051567)2.66891833
77mRNA polyadenylation (GO:0006378)2.66482864
78glutathione biosynthetic process (GO:0006750)2.65577016
79regulation of mammary gland epithelial cell proliferation (GO:0033599)2.64797127
80erythrocyte maturation (GO:0043249)2.62555601
81response to muramyl dipeptide (GO:0032495)2.62287422
82positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.62216482
83entrainment of circadian clock by photoperiod (GO:0043153)2.59428048
84glucose 6-phosphate metabolic process (GO:0051156)2.59210743
85lung epithelium development (GO:0060428)2.59001102
86protein deacetylation (GO:0006476)2.57687061
87peptidyl-arginine omega-N-methylation (GO:0035247)2.57049425
88regulation of histone methylation (GO:0031060)2.55558368
89histone H4-K12 acetylation (GO:0043983)2.54379959
90mitochondrion localization (GO:0051646)2.52799421
91ribosomal small subunit biogenesis (GO:0042274)2.52581231
92maintenance of protein localization in organelle (GO:0072595)2.52564203
93activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.49223612
94regulation of monocyte differentiation (GO:0045655)2.48813269
95spliceosomal tri-snRNP complex assembly (GO:0000244)2.46866505
96protein export from nucleus (GO:0006611)2.43126244
97positive regulation of gene expression, epigenetic (GO:0045815)2.41743903
98sensory perception of taste (GO:0050909)2.40813320
99positive regulation of nuclease activity (GO:0032075)2.40313514
100apoptotic process involved in morphogenesis (GO:0060561)2.39176672

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1VDR_21846776_ChIP-Seq_THP-1_Human3.17812701
2* LXR_22292898_ChIP-Seq_THP-1_Human2.94190872
3THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.75011214
4MYC_22102868_ChIP-Seq_BL_Human2.69307536
5TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.66506566
6EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.50974549
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.45240303
8* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.40000627
9P68_20966046_ChIP-Seq_HELA_Human2.26474580
10* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.26122272
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14511209
12RACK7_27058665_Chip-Seq_MCF-7_Human2.12162101
13* KDM2B_26808549_Chip-Seq_DND41_Human2.11449977
14* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.11349197
15ELK3_25401928_ChIP-Seq_HUVEC_Human2.10341956
16TCF7_22412390_ChIP-Seq_EML_Mouse1.90978385
17ERG_21242973_ChIP-ChIP_JURKAT_Human1.84016729
18SMC4_20622854_ChIP-Seq_HELA_Human1.80502027
19ZNF263_19887448_ChIP-Seq_K562_Human1.79118943
20EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.78415214
21TET1_21451524_ChIP-Seq_MESCs_Mouse1.78405116
22SA1_27219007_Chip-Seq_ERYTHROID_Human1.78018428
23* MAF_26560356_Chip-Seq_TH2_Human1.77506179
24CTCF_27219007_Chip-Seq_ERYTHROID_Human1.76709283
25* NCOR1_26117541_ChIP-Seq_K562_Human1.75864685
26DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.75834665
27EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.75353952
28XRN2_22483619_ChIP-Seq_HELA_Human1.74780711
29ELF1_20517297_ChIP-Seq_JURKAT_Human1.69105101
30KDM2B_26808549_Chip-Seq_K562_Human1.67465526
31PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.66185841
32* CREB1_26743006_Chip-Seq_LNCaP_Human1.65366794
33CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.62745659
34SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.62662267
35BCL6_27268052_Chip-Seq_Bcells_Human1.59602871
36MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58928572
37BCOR_27268052_Chip-Seq_Bcells_Human1.57699623
38ZFP281_18757296_ChIP-ChIP_E14_Mouse1.55542708
39MAF_26560356_Chip-Seq_TH1_Human1.50946904
40RARG_19884340_ChIP-ChIP_MEFs_Mouse1.50923566
41CIITA_25753668_ChIP-Seq_RAJI_Human1.50790112
42* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47638690
43DNAJC2_21179169_ChIP-ChIP_NT2_Human1.46510020
44* CTCF_27219007_Chip-Seq_Bcells_Human1.45215529
45E2F1_20622854_ChIP-Seq_HELA_Human1.44872333
46CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.44217886
47MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.43740682
48UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.43427704
49PHF8_20622854_ChIP-Seq_HELA_Human1.42575547
50SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.40790156
51* UTX_26944678_Chip-Seq_JUKART_Human1.40229100
52KDM2B_26808549_Chip-Seq_JURKAT_Human1.40191888
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.37751681
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.35763577
55MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35750790
56SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.35091706
57RARB_24833708_ChIP-Seq_LIVER_Mouse1.33744674
58* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.32905150
59* FOXP1_21924763_ChIP-Seq_HESCs_Human1.32487618
60CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.31658734
61E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.31081666
62RARA_24833708_ChIP-Seq_LIVER_Mouse1.30111321
63VDR_24763502_ChIP-Seq_THP-1_Human1.26497256
64SA1_27219007_Chip-Seq_Bcells_Human1.25205162
65ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.22842511
66JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.21764917
67SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.21751049
68* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.21632076
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.17928420
70KDM5A_27292631_Chip-Seq_BREAST_Human1.17773455
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17534529
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17328114
73* CTCF_21964334_Chip-Seq_Bcells_Human1.17293649
74CTCF_26484167_Chip-Seq_Bcells_Mouse1.17172921
75SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.16915109
76IKZF1_21737484_ChIP-ChIP_HCT116_Human1.14979182
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14956249
78RUNX1_22412390_ChIP-Seq_EML_Mouse1.11411497
79RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.11210549
80SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.10966682
81PU.1_20513432_ChIP-Seq_Bcells_Mouse1.10796838
82ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.10710446
83ETS1_21867929_ChIP-Seq_TH2_Mouse1.10545265
84TP63_17297297_ChIP-ChIP_HaCaT_Human1.09541400
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09029660
86YY1_22570637_ChIP-Seq_MALME-3M_Human1.08603866
87TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.07715853
88* GABP_19822575_ChIP-Seq_HepG2_Human1.06909527
89TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.06846820
90RUNX1_27514584_Chip-Seq_MCF-7_Human1.06305502
91CTCF_20526341_ChIP-Seq_ESCs_Human1.06305071
92YY1_21170310_ChIP-Seq_MESCs_Mouse1.06281993
93MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06252419
94KLF4_18555785_ChIP-Seq_MESCs_Mouse1.04491969
95MYC_19079543_ChIP-ChIP_MESCs_Mouse1.04178050
96EGR1_19374776_ChIP-ChIP_THP-1_Human1.02411535
97SCL_19346495_ChIP-Seq_HPC-7_Human1.02083490
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01922667
99RARB_27405468_Chip-Seq_BRAIN_Mouse1.00087855
100DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00033991

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003172_abnormal_lysosome_physiology3.39348367
2MP0004859_abnormal_synaptic_plasticity3.12035346
3MP0008260_abnormal_autophagy2.93523278
4MP0009278_abnormal_bone_marrow2.84390449
5MP0005083_abnormal_biliary_tract2.75400188
6MP0002249_abnormal_larynx_morphology2.69947814
7MP0005171_absent_coat_pigmentation2.65503591
8MP0005451_abnormal_body_composition2.61668848
9MP0000678_abnormal_parathyroid_gland2.56726816
10MP0003705_abnormal_hypodermis_morpholog2.45704168
11MP0005058_abnormal_lysosome_morphology2.42817793
12MP0005423_abnormal_somatic_nervous2.32468106
13MP0001545_abnormal_hematopoietic_system2.19930283
14MP0005397_hematopoietic_system_phenotyp2.19930283
15MP0004858_abnormal_nervous_system2.14818221
16MP0005076_abnormal_cell_differentiation2.04986988
17MP0001849_ear_inflammation2.04739408
18MP0004381_abnormal_hair_follicle2.00754503
19MP0002132_abnormal_respiratory_system1.95073817
20MP0001502_abnormal_circadian_rhythm1.94292120
21MP0008995_early_reproductive_senescence1.87750035
22MP0000003_abnormal_adipose_tissue1.85870390
23MP0003656_abnormal_erythrocyte_physiolo1.69972252
24MP0000566_synostosis1.68165453
25MP0002396_abnormal_hematopoietic_system1.68110636
26MP0001348_abnormal_lacrimal_gland1.65234871
27MP0003111_abnormal_nucleus_morphology1.53824180
28MP0000751_myopathy1.51810514
29MP0005394_taste/olfaction_phenotype1.51399624
30MP0005499_abnormal_olfactory_system1.51399624
31MP0005409_darkened_coat_color1.45863885
32MP0005666_abnormal_adipose_tissue1.41632925
33MP0003436_decreased_susceptibility_to1.35413771
34MP0001986_abnormal_taste_sensitivity1.33362187
35MP0001873_stomach_inflammation1.32893045
36MP0005375_adipose_tissue_phenotype1.32736282
37MP0005360_urolithiasis1.32289078
38MP0002089_abnormal_postnatal_growth/wei1.30700996
39MP0002822_catalepsy1.29537030
40MP0004185_abnormal_adipocyte_glucose1.28436322
41MP0003878_abnormal_ear_physiology1.25664521
42MP0005377_hearing/vestibular/ear_phenot1.25664521
43MP0003635_abnormal_synaptic_transmissio1.21260473
44MP0004147_increased_porphyrin_level1.12257420
45MP0009931_abnormal_skin_appearance1.10698702
46MP0000013_abnormal_adipose_tissue1.05123292
47MP0002653_abnormal_ependyma_morphology1.03707850
48MP0008569_lethality_at_weaning1.03569908
49MP0003693_abnormal_embryo_hatching1.02079328
50MP0003123_paternal_imprinting1.01457292
51MP0010030_abnormal_orbit_morphology1.00438759
52MP0009384_cardiac_valve_regurgitation1.00007049
53MP0000747_muscle_weakness0.98367138
54MP0003183_abnormal_peptide_metabolism0.97748898
55MP0003329_amyloid_beta_deposits0.97731018
56MP0002063_abnormal_learning/memory/cond0.97682737
57MP0008789_abnormal_olfactory_epithelium0.97043431
58MP0009840_abnormal_foam_cell0.96785896
59MP0000313_abnormal_cell_death0.94662875
60MP0003453_abnormal_keratinocyte_physiol0.94353227
61MP0003136_yellow_coat_color0.90864502
62MP0003303_peritoneal_inflammation0.90576458
63MP0003763_abnormal_thymus_physiology0.90499921
64MP0003938_abnormal_ear_development0.88372841
65MP0000703_abnormal_thymus_morphology0.84296688
66MP0003879_abnormal_hair_cell0.83947439
67MP0003115_abnormal_respiratory_system0.81913760
68MP0003690_abnormal_glial_cell0.81204570
69MP0000015_abnormal_ear_pigmentation0.80729722
70MP0000681_abnormal_thyroid_gland0.80330508
71MP0002398_abnormal_bone_marrow0.79382875
72MP0004947_skin_inflammation0.79342094
73MP0005501_abnormal_skin_physiology0.79069878
74MP0003077_abnormal_cell_cycle0.79059328
75MP0001270_distended_abdomen0.78782285
76MP0004197_abnormal_fetal_growth/weight/0.78365929
77MP0002080_prenatal_lethality0.78272089
78MP0002970_abnormal_white_adipose0.73613317
79MP0006036_abnormal_mitochondrial_physio0.73554843
80MP0002019_abnormal_tumor_incidence0.71861767
81MP0009672_abnormal_birth_weight0.71858199
82MP0006035_abnormal_mitochondrial_morpho0.70961331
83MP0001730_embryonic_growth_arrest0.70527975
84MP0003385_abnormal_body_wall0.70405692
85MP0010094_abnormal_chromosome_stability0.68929035
86MP0000750_abnormal_muscle_regeneration0.68549401
87MP0003948_abnormal_gas_homeostasis0.68100215
88MP0008874_decreased_physiological_sensi0.67400845
89MP0004811_abnormal_neuron_physiology0.66600614
90MP0002169_no_abnormal_phenotype0.66267355
91MP0006138_congestive_heart_failure0.66143665
92MP0002873_normal_phenotype0.65909581
93MP0002429_abnormal_blood_cell0.65423581
94MP0002075_abnormal_coat/hair_pigmentati0.65135738
95MP0009333_abnormal_splenocyte_physiolog0.64300471
96MP0000350_abnormal_cell_proliferation0.62749933
97MP0002933_joint_inflammation0.62079300
98MP0002932_abnormal_joint_morphology0.61441809
99MP0000467_abnormal_esophagus_morphology0.60407286
100MP0002722_abnormal_immune_system0.60074358

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytosis (HP:0001923)4.65512263
2Abnormal gallbladder physiology (HP:0012438)4.45189015
3Cholecystitis (HP:0001082)4.45189015
4Truncus arteriosus (HP:0001660)3.81512268
5Annular pancreas (HP:0001734)3.70048462
6Abnormality of reticulocytes (HP:0004312)3.64005721
7Hyperthyroidism (HP:0000836)3.62475975
8Metaphyseal cupping (HP:0003021)3.41240126
9Hyperacusis (HP:0010780)3.35736732
10Thin bony cortex (HP:0002753)3.33790342
11J-shaped sella turcica (HP:0002680)3.26371445
12Obstructive sleep apnea (HP:0002870)3.19642144
13Atelectasis (HP:0100750)3.17930592
14Myopathic facies (HP:0002058)3.08690279
15Hypertensive crisis (HP:0100735)3.07970161
16Testicular atrophy (HP:0000029)3.07827312
17Seborrheic dermatitis (HP:0001051)3.05058523
18Stridor (HP:0010307)2.90906176
19Insomnia (HP:0100785)2.86839916
20Pointed chin (HP:0000307)2.85272652
21Abnormality of the heme biosynthetic pathway (HP:0010472)2.80432067
22Cholelithiasis (HP:0001081)2.72810399
23Microvesicular hepatic steatosis (HP:0001414)2.70880944
24Upper limb amyotrophy (HP:0009129)2.70513726
25Distal upper limb amyotrophy (HP:0007149)2.70513726
26Ankle clonus (HP:0011448)2.67751794
27Ragged-red muscle fibers (HP:0003200)2.64187531
28Broad face (HP:0000283)2.64007524
29Rib fusion (HP:0000902)2.62005442
30Ulnar bowing (HP:0003031)2.61834161
31Hypoparathyroidism (HP:0000829)2.60574971
32Abnormality of the fingertips (HP:0001211)2.56812165
33Turricephaly (HP:0000262)2.53205563
34Biconcave vertebral bodies (HP:0004586)2.52917351
35Bowel incontinence (HP:0002607)2.50971064
36Spinal canal stenosis (HP:0003416)2.50733620
37Broad palm (HP:0001169)2.50457051
38Colitis (HP:0002583)2.46104127
39Easy fatigability (HP:0003388)2.41835520
40Peripheral hypomyelination (HP:0007182)2.38287155
41Progressive external ophthalmoplegia (HP:0000590)2.30316432
42Abnormal large intestine physiology (HP:0012700)2.30180129
43Thin ribs (HP:0000883)2.30044159
44Pallor (HP:0000980)2.29164655
45Cerebral aneurysm (HP:0004944)2.27316154
46Papilledema (HP:0001085)2.26322954
47Poikiloderma (HP:0001029)2.26247496
48Supranuclear gaze palsy (HP:0000605)2.26139178
49Hemorrhage of the eye (HP:0011885)2.24604035
50Disproportionate tall stature (HP:0001519)2.22757498
51Hand muscle atrophy (HP:0009130)2.22701988
52Abnormality of cochlea (HP:0000375)2.22349612
53Facial hemangioma (HP:0000329)2.21578288
54Abnormal gallbladder morphology (HP:0012437)2.20336284
55Abnormality of the thoracic spine (HP:0100711)2.20196047
56Morphological abnormality of the inner ear (HP:0011390)2.16389111
57Cervical subluxation (HP:0003308)2.15056047
58Exercise-induced myalgia (HP:0003738)2.13542684
59Abnormality of cells of the erythroid lineage (HP:0012130)2.06326149
60Flat acetabular roof (HP:0003180)2.04049343
61Abnormality of the gallbladder (HP:0005264)2.02817737
62Deep palmar crease (HP:0006191)2.01613351
63Obstructive lung disease (HP:0006536)2.00586369
64Chronic obstructive pulmonary disease (HP:0006510)2.00586369
65Neuronal loss in central nervous system (HP:0002529)1.97563419
66Gastrointestinal dysmotility (HP:0002579)1.95938656
67Gastrointestinal inflammation (HP:0004386)1.95185838
68Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.94874829
69Absent epiphyses (HP:0010577)1.94874829
70Joint stiffness (HP:0001387)1.94523720
71Squamous cell carcinoma (HP:0002860)1.91577875
72Thoracic kyphosis (HP:0002942)1.90200242
73Nuclear cataract (HP:0100018)1.89848687
74Polycythemia (HP:0001901)1.89639943
75Long palpebral fissure (HP:0000637)1.89309056
76Cerebral hypomyelination (HP:0006808)1.87595162
77Abnormally folded helix (HP:0008544)1.86331146
78Abnormality of the tricuspid valve (HP:0001702)1.86209582
79Abnormal number of erythroid precursors (HP:0012131)1.85254256
80Obsessive-compulsive behavior (HP:0000722)1.80896191
81Premature skin wrinkling (HP:0100678)1.79533202
82Abnormal hemoglobin (HP:0011902)1.78632094
83Deformed sella turcica (HP:0002681)1.78463741
84Ocular albinism (HP:0001107)1.75742804
85Hypoplasia of the capital femoral epiphysis (HP:0003090)1.75064151
86Diaphragmatic weakness (HP:0009113)1.73878947
87Increased nuchal translucency (HP:0010880)1.73207398
88Patellar dislocation (HP:0002999)1.72961179
89Supernumerary nipples (HP:0002558)1.72370606
90Abnormality of lateral ventricle (HP:0030047)1.71687343
91Flat cornea (HP:0007720)1.71545210
9211 pairs of ribs (HP:0000878)1.67326577
93Aplasia/Hypoplasia of the thymus (HP:0010515)1.67208496
94Increased IgE level (HP:0003212)1.67100295
95Ankyloglossia (HP:0010296)1.65008140
96Flared metaphyses (HP:0003015)1.64610609
97Personality changes (HP:0000751)1.63035561
98Bronchomalacia (HP:0002780)1.61434831
99Acanthocytosis (HP:0001927)1.61295406
100Myokymia (HP:0002411)1.61271830

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.51561530
2RIPK43.13642983
3MAPK152.92957276
4SIK12.89036223
5SIK22.76830748
6ICK2.72028613
7ERN12.71569255
8TNK22.36749866
9EEF2K2.23110423
10SMG12.02456618
11NME21.89028314
12PKN21.81622682
13MARK21.70149235
14FGFR41.68797877
15MAP4K11.67705492
16PRPF4B1.66226403
17MST1R1.60997263
18MAP2K31.58760641
19BMX1.55546004
20NME11.53725816
21MAP3K71.52392068
22MAP2K61.47580684
23NTRK31.46474297
24MAP3K61.43145977
25CDK121.38321052
26KSR21.34575722
27PRKD31.28243479
28MAP3K131.22705504
29SIK31.20034075
30TYRO31.15977613
31PRKD21.11016065
32MTOR1.04141534
33MAP3K111.01918559
34MAPK121.01606723
35CAMKK10.96962537
36PTK60.95305453
37MAP2K40.91327693
38RPS6KA20.90859051
39CDC42BPA0.89793579
40MAP3K100.88503337
41PDPK10.87886029
42GRK60.87684967
43RAF10.87357330
44MAPK110.82592879
45TYK20.82567718
46TBK10.79774179
47ZAP700.77950793
48BTK0.75606543
49WNK40.74792779
50LRRK20.73967817
51IRAK20.72516861
52RPS6KL10.70754348
53RPS6KC10.70754348
54RPS6KB20.68279460
55MAPK100.68220026
56NTRK20.67862461
57JAK30.67142190
58RET0.65812818
59RIPK10.65353360
60MET0.65031140
61MAP2K20.62125911
62CDK40.59421282
63MAP3K90.58452639
64MAPK80.56330225
65UHMK10.56118887
66MAP3K10.55653680
67RPS6KA60.55432940
68EPHB10.55417112
69PDGFRA0.55302631
70IRAK30.52766157
71CDK11A0.52006971
72EPHA20.51994545
73BRAF0.51527730
74EIF2AK10.50939517
75MAPK30.50636443
76BLK0.50504384
77DYRK1B0.49799585
78PRKD10.49226805
79CCNB10.49042859
80CDK20.48198241
81PDK10.47949581
82ERBB20.47799011
83MARK10.47198046
84PRKCH0.46921841
85CDK150.44181711
86NEK60.44181174
87PRKCI0.43850086
88CDK70.43484076
89PIM20.43359234
90NTRK10.42411770
91ATR0.41955145
92ARAF0.41478657
93MATK0.41357066
94MAPK40.40561061
95FGFR30.40314789
96TAOK30.40054476
97CDK10.39734037
98PTK20.37823683
99GSK3B0.37736086
100CDK180.37049605

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005113.77289767
2Sulfur relay system_Homo sapiens_hsa041222.61358264
3Notch signaling pathway_Homo sapiens_hsa043302.52993954
4Fructose and mannose metabolism_Homo sapiens_hsa000512.52303895
5Other types of O-glycan biosynthesis_Homo sapiens_hsa005142.51191328
6Acute myeloid leukemia_Homo sapiens_hsa052212.47647929
7VEGF signaling pathway_Homo sapiens_hsa043702.47000798
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.20376409
9Glycosaminoglycan degradation_Homo sapiens_hsa005312.12460130
10mTOR signaling pathway_Homo sapiens_hsa041501.97695203
11Cyanoamino acid metabolism_Homo sapiens_hsa004601.97098066
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.83659714
13Non-small cell lung cancer_Homo sapiens_hsa052231.74089161
14Chronic myeloid leukemia_Homo sapiens_hsa052201.63826909
15Biosynthesis of amino acids_Homo sapiens_hsa012301.58122575
16Base excision repair_Homo sapiens_hsa034101.54503036
17Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.54398731
18ErbB signaling pathway_Homo sapiens_hsa040121.53976655
19Choline metabolism in cancer_Homo sapiens_hsa052311.46252760
20B cell receptor signaling pathway_Homo sapiens_hsa046621.42974924
21mRNA surveillance pathway_Homo sapiens_hsa030151.40359553
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38013839
23Thyroid hormone signaling pathway_Homo sapiens_hsa049191.36590645
24Glycerophospholipid metabolism_Homo sapiens_hsa005641.35726664
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.33513160
26Neurotrophin signaling pathway_Homo sapiens_hsa047221.30959711
27GnRH signaling pathway_Homo sapiens_hsa049121.28630019
28Central carbon metabolism in cancer_Homo sapiens_hsa052301.26408032
29Carbohydrate digestion and absorption_Homo sapiens_hsa049731.25734929
30Synaptic vesicle cycle_Homo sapiens_hsa047211.19883763
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.16824467
32Insulin signaling pathway_Homo sapiens_hsa049101.16155643
33Phospholipase D signaling pathway_Homo sapiens_hsa040721.15535040
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.14729961
35Lysine degradation_Homo sapiens_hsa003101.14228238
36Long-term potentiation_Homo sapiens_hsa047201.13884761
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13848860
38Glioma_Homo sapiens_hsa052141.12756797
39Inositol phosphate metabolism_Homo sapiens_hsa005621.11445228
40Bladder cancer_Homo sapiens_hsa052191.06940606
41Longevity regulating pathway - mammal_Homo sapiens_hsa042111.02809646
42Arginine biosynthesis_Homo sapiens_hsa002201.00349398
43AMPK signaling pathway_Homo sapiens_hsa041520.99520416
44Spliceosome_Homo sapiens_hsa030400.97802528
45ABC transporters_Homo sapiens_hsa020100.97138097
46Estrogen signaling pathway_Homo sapiens_hsa049150.96023095
47Prion diseases_Homo sapiens_hsa050200.93820031
48Pentose phosphate pathway_Homo sapiens_hsa000300.93387785
49Prolactin signaling pathway_Homo sapiens_hsa049170.91065869
50Aldosterone synthesis and secretion_Homo sapiens_hsa049250.90172513
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.84223905
52Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.81327347
53Ribosome_Homo sapiens_hsa030100.80944707
54Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80764628
55Pancreatic cancer_Homo sapiens_hsa052120.80586775
56Endometrial cancer_Homo sapiens_hsa052130.77590586
57Endocytosis_Homo sapiens_hsa041440.77534083
58Adipocytokine signaling pathway_Homo sapiens_hsa049200.70631434
59Hepatitis C_Homo sapiens_hsa051600.70338136
60Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.70169257
61Cocaine addiction_Homo sapiens_hsa050300.69213516
62Fanconi anemia pathway_Homo sapiens_hsa034600.68384818
63Thyroid cancer_Homo sapiens_hsa052160.68127758
64AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64665900
65Axon guidance_Homo sapiens_hsa043600.62450397
66Viral carcinogenesis_Homo sapiens_hsa052030.59924621
67HIF-1 signaling pathway_Homo sapiens_hsa040660.59563503
68Hepatitis B_Homo sapiens_hsa051610.59533385
69Amphetamine addiction_Homo sapiens_hsa050310.59022981
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.58003838
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.57576801
72Nicotine addiction_Homo sapiens_hsa050330.54695450
73MAPK signaling pathway_Homo sapiens_hsa040100.53961292
74Renal cell carcinoma_Homo sapiens_hsa052110.51693778
75Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51537313
76Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.51386303
77Galactose metabolism_Homo sapiens_hsa000520.51376458
78N-Glycan biosynthesis_Homo sapiens_hsa005100.50749755
79Epstein-Barr virus infection_Homo sapiens_hsa051690.50725065
80Colorectal cancer_Homo sapiens_hsa052100.49272343
81Insulin resistance_Homo sapiens_hsa049310.49224005
82RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48687122
83Insulin secretion_Homo sapiens_hsa049110.47457935
84Melanogenesis_Homo sapiens_hsa049160.46707609
85Taste transduction_Homo sapiens_hsa047420.46534611
86Carbon metabolism_Homo sapiens_hsa012000.46435803
87Influenza A_Homo sapiens_hsa051640.43177470
88T cell receptor signaling pathway_Homo sapiens_hsa046600.42479773
89Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.41534094
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.41015312
91DNA replication_Homo sapiens_hsa030300.39144685
92Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38497978
93Toll-like receptor signaling pathway_Homo sapiens_hsa046200.38156162
94HTLV-I infection_Homo sapiens_hsa051660.37570012
95Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.37476661
96Herpes simplex infection_Homo sapiens_hsa051680.36602557
97Osteoclast differentiation_Homo sapiens_hsa043800.35713448
98RNA transport_Homo sapiens_hsa030130.35024746
99Type II diabetes mellitus_Homo sapiens_hsa049300.34007620
100Glucagon signaling pathway_Homo sapiens_hsa049220.32603996

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