ZNF624

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.20767834
2neural tube formation (GO:0001841)5.53579072
3nucleobase catabolic process (GO:0046113)5.15823472
4presynaptic membrane assembly (GO:0097105)4.53603546
5limb bud formation (GO:0060174)4.43113278
6presynaptic membrane organization (GO:0097090)4.12040923
7behavioral response to nicotine (GO:0035095)4.04986450
8regulation of hexokinase activity (GO:1903299)3.93898077
9regulation of glucokinase activity (GO:0033131)3.93898077
10response to pheromone (GO:0019236)3.77694584
11L-fucose catabolic process (GO:0042355)3.73353262
12fucose catabolic process (GO:0019317)3.73353262
13L-fucose metabolic process (GO:0042354)3.73353262
14nonmotile primary cilium assembly (GO:0035058)3.58077617
15regulation of meiosis I (GO:0060631)3.51198784
16glial cell proliferation (GO:0014009)3.49285481
17epithelial cilium movement (GO:0003351)3.46523611
18cornea development in camera-type eye (GO:0061303)3.36335156
19platelet dense granule organization (GO:0060155)3.35882525
20sympathetic nervous system development (GO:0048485)3.35049082
21somite development (GO:0061053)3.31346670
22embryonic epithelial tube formation (GO:0001838)3.27928999
23mechanosensory behavior (GO:0007638)3.21697154
24neuron cell-cell adhesion (GO:0007158)3.20443088
25proline transport (GO:0015824)3.19301814
26kidney morphogenesis (GO:0060993)3.17865213
27regulation of cilium movement (GO:0003352)3.16784287
28intraciliary transport (GO:0042073)3.16607822
29epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.11681889
30postsynaptic membrane organization (GO:0001941)3.11485936
31protein localization to cilium (GO:0061512)3.10888199
32C4-dicarboxylate transport (GO:0015740)3.10850457
33auditory behavior (GO:0031223)3.06556699
34behavioral response to ethanol (GO:0048149)3.02983123
35epithelial tube formation (GO:0072175)3.01762256
36spinal cord development (GO:0021510)2.99627851
37axoneme assembly (GO:0035082)2.95180075
38protein-cofactor linkage (GO:0018065)2.94492491
39retinal ganglion cell axon guidance (GO:0031290)2.94106534
40detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.93205944
41photoreceptor cell maintenance (GO:0045494)2.92833499
42brain morphogenesis (GO:0048854)2.92606085
43olfactory bulb development (GO:0021772)2.92206130
44cilium organization (GO:0044782)2.89529935
45central nervous system neuron axonogenesis (GO:0021955)2.87436113
46cilium assembly (GO:0042384)2.86958711
47piRNA metabolic process (GO:0034587)2.86530134
48establishment of protein localization to Golgi (GO:0072600)2.85393613
49negative regulation of mast cell activation (GO:0033004)2.84457106
50axonal fasciculation (GO:0007413)2.83448477
51prenylation (GO:0097354)2.83347616
52protein prenylation (GO:0018342)2.83347616
53cilium morphogenesis (GO:0060271)2.81893810
54DNA integration (GO:0015074)2.79755286
55reflex (GO:0060004)2.78943407
56regulation of collateral sprouting (GO:0048670)2.77875645
57inositol phosphate catabolic process (GO:0071545)2.77583042
58protein targeting to Golgi (GO:0000042)2.76605698
59indolalkylamine metabolic process (GO:0006586)2.75356435
60anterograde synaptic vesicle transport (GO:0048490)2.73345014
61DNA double-strand break processing (GO:0000729)2.72481607
62cellular ketone body metabolic process (GO:0046950)2.72099584
63ubiquinone biosynthetic process (GO:0006744)2.71444975
64calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.71051777
65ketone body metabolic process (GO:1902224)2.69644952
66protein K11-linked deubiquitination (GO:0035871)2.67787652
67central nervous system projection neuron axonogenesis (GO:0021952)2.67709507
68ubiquinone metabolic process (GO:0006743)2.67591348
69cell proliferation in forebrain (GO:0021846)2.67516266
70glycosphingolipid biosynthetic process (GO:0006688)2.67297458
71cilium movement (GO:0003341)2.67148282
72alanine transport (GO:0032328)2.67048659
73protein complex biogenesis (GO:0070271)2.66900150
74preassembly of GPI anchor in ER membrane (GO:0016254)2.66714834
75replication fork processing (GO:0031297)2.64588058
76hindbrain development (GO:0030902)2.64475371
77mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.64280955
78mitochondrial respiratory chain complex I assembly (GO:0032981)2.64280955
79NADH dehydrogenase complex assembly (GO:0010257)2.64280955
80negative regulation of transcription regulatory region DNA binding (GO:2000678)2.62758377
81cerebral cortex radially oriented cell migration (GO:0021799)2.59751616
82neurotransmitter-gated ion channel clustering (GO:0072578)2.58156633
83protein localization to Golgi apparatus (GO:0034067)2.58031978
84synapse assembly (GO:0007416)2.57654552
85regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.57614525
86keratinocyte development (GO:0003334)2.55561814
87transmission of nerve impulse (GO:0019226)2.55207857
88respiratory chain complex IV assembly (GO:0008535)2.55106617
89gamma-aminobutyric acid transport (GO:0015812)2.54290464
90regulation of telomere maintenance (GO:0032204)2.54279545
91protein polyglutamylation (GO:0018095)2.54180755
92retinal cone cell development (GO:0046549)2.53816850
93startle response (GO:0001964)2.53281246
94vocalization behavior (GO:0071625)2.53132788
95DNA methylation involved in gamete generation (GO:0043046)2.49249836
96mitochondrial respiratory chain complex assembly (GO:0033108)2.48423571
97positive regulation of oligodendrocyte differentiation (GO:0048714)2.48098095
98cytochrome complex assembly (GO:0017004)2.45333183
99protein K6-linked ubiquitination (GO:0085020)2.44866951
100negative regulation of systemic arterial blood pressure (GO:0003085)2.43916501

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.16931055
2GBX2_23144817_ChIP-Seq_PC3_Human3.09643888
3POU3F2_20337985_ChIP-ChIP_501MEL_Human3.00718916
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.98884183
5IGF1R_20145208_ChIP-Seq_DFB_Human2.94232474
6CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.86246621
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.65632323
8VDR_22108803_ChIP-Seq_LS180_Human2.58840137
9EZH2_22144423_ChIP-Seq_EOC_Human2.56071916
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.43381284
11EWS_26573619_Chip-Seq_HEK293_Human2.35967831
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.34149828
13TAF15_26573619_Chip-Seq_HEK293_Human2.34056916
14FUS_26573619_Chip-Seq_HEK293_Human2.31142324
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.28376061
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.22922467
17CTBP1_25329375_ChIP-Seq_LNCAP_Human2.20540326
18FLI1_27457419_Chip-Seq_LIVER_Mouse2.18448301
19P300_19829295_ChIP-Seq_ESCs_Human2.17137762
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.06997953
21ER_23166858_ChIP-Seq_MCF-7_Human1.95706011
22AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.94022089
23PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.88945080
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.83905191
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.81703327
26SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.80735996
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77166159
28* SMAD4_21799915_ChIP-Seq_A2780_Human1.75394756
29MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.71669963
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.68410888
31CBP_20019798_ChIP-Seq_JUKART_Human1.67130235
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.67130235
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67016678
34OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64654091
35UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.63412802
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.60675851
37SUZ12_27294783_Chip-Seq_NPCs_Mouse1.57777475
38STAT3_23295773_ChIP-Seq_U87_Human1.56056761
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.53441711
40SMAD3_21741376_ChIP-Seq_EPCs_Human1.53337121
41NANOG_18555785_Chip-Seq_ESCs_Mouse1.53027843
42SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.51941180
43NR3C1_21868756_ChIP-Seq_MCF10A_Human1.47232730
44IRF1_19129219_ChIP-ChIP_H3396_Human1.46916018
45NFE2_27457419_Chip-Seq_LIVER_Mouse1.46463614
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.46409879
47AR_25329375_ChIP-Seq_VCAP_Human1.45695378
48EZH2_27294783_Chip-Seq_NPCs_Mouse1.44564478
49PCGF2_27294783_Chip-Seq_NPCs_Mouse1.43209892
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41745786
51* TCF4_23295773_ChIP-Seq_U87_Human1.40060380
52BCAT_22108803_ChIP-Seq_LS180_Human1.39334615
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38723366
54EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.37726725
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36423746
56P53_22387025_ChIP-Seq_ESCs_Mouse1.35367260
57TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33250400
58POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33250400
59RUNX2_22187159_ChIP-Seq_PCA_Human1.29925554
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27381646
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26452872
62TP53_22573176_ChIP-Seq_HFKS_Human1.26209250
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25507889
64NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.25102243
65CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24858977
66SUZ12_18555785_Chip-Seq_ESCs_Mouse1.24740940
67E2F1_18555785_Chip-Seq_ESCs_Mouse1.24427223
68ELK1_19687146_ChIP-ChIP_HELA_Human1.23501195
69RNF2_27304074_Chip-Seq_NSC_Mouse1.23345048
70TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.22478857
71TCF4_22108803_ChIP-Seq_LS180_Human1.22332658
72NANOG_19829295_ChIP-Seq_ESCs_Human1.20760667
73SOX2_19829295_ChIP-Seq_ESCs_Human1.20760667
74CMYC_18555785_Chip-Seq_ESCs_Mouse1.18923679
75REST_21632747_ChIP-Seq_MESCs_Mouse1.18138266
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16669606
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.16480089
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.16360329
79CRX_20693478_ChIP-Seq_RETINA_Mouse1.15191726
80GABP_17652178_ChIP-ChIP_JURKAT_Human1.14605165
81STAT3_18555785_Chip-Seq_ESCs_Mouse1.13508801
82ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.10988239
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.10843743
84P300_18555785_Chip-Seq_ESCs_Mouse1.10625507
85EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.09888671
86EST1_17652178_ChIP-ChIP_JURKAT_Human1.09108594
87MYC_18940864_ChIP-ChIP_HL60_Human1.09003127
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.06620299
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.06488427
90E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04418263
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04172479
92SMAD4_21741376_ChIP-Seq_EPCs_Human1.04127668
93BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03651948
94OCT4_18555785_Chip-Seq_ESCs_Mouse1.02819822
95SOX2_18555785_Chip-Seq_ESCs_Mouse1.02345299
96RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01651781
97AR_21572438_ChIP-Seq_LNCaP_Human1.01449854
98KDM2B_26808549_Chip-Seq_REH_Human1.00955133
99TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99986069
100TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99937999

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.46194926
2MP0003787_abnormal_imprinting3.29034599
3MP0003880_abnormal_central_pattern3.14108556
4MP0001529_abnormal_vocalization2.65460161
5MP0005645_abnormal_hypothalamus_physiol2.64230203
6MP0002102_abnormal_ear_morphology2.55462628
7MP0008877_abnormal_DNA_methylation2.52494569
8MP0002736_abnormal_nociception_after2.48829767
9MP0000372_irregular_coat_pigmentation2.32399337
10MP0001968_abnormal_touch/_nociception2.20614368
11MP0002163_abnormal_gland_morphology2.07670173
12MP0003121_genomic_imprinting2.06510966
13MP0003195_calcinosis1.96526455
14MP0001984_abnormal_olfaction1.93554321
15MP0005551_abnormal_eye_electrophysiolog1.90971239
16MP0003122_maternal_imprinting1.87938592
17MP0005253_abnormal_eye_physiology1.82473011
18MP0005075_abnormal_melanosome_morpholog1.79128591
19MP0002638_abnormal_pupillary_reflex1.79118883
20MP0006276_abnormal_autonomic_nervous1.74345439
21MP0005379_endocrine/exocrine_gland_phen1.70060119
22MP0000778_abnormal_nervous_system1.68167881
23MP0006292_abnormal_olfactory_placode1.66531267
24MP0008789_abnormal_olfactory_epithelium1.65552447
25MP0006072_abnormal_retinal_apoptosis1.63836781
26MP0002928_abnormal_bile_duct1.63797466
27MP0002837_dystrophic_cardiac_calcinosis1.63493968
28MP0002751_abnormal_autonomic_nervous1.61965340
29MP0005084_abnormal_gallbladder_morpholo1.60980254
30MP0002653_abnormal_ependyma_morphology1.60430290
31MP0002234_abnormal_pharynx_morphology1.58220668
32MP0002272_abnormal_nervous_system1.55917381
33MP0003011_delayed_dark_adaptation1.55152231
34MP0009046_muscle_twitch1.49550610
35MP0000427_abnormal_hair_cycle1.49069028
36MP0004133_heterotaxia1.48427460
37MP0004885_abnormal_endolymph1.45196048
38MP0001486_abnormal_startle_reflex1.42001824
39MP0009745_abnormal_behavioral_response1.36838716
40MP0002557_abnormal_social/conspecific_i1.34545356
41MP0008058_abnormal_DNA_repair1.33478085
42MP0004147_increased_porphyrin_level1.31789552
43MP0005499_abnormal_olfactory_system1.31436234
44MP0005394_taste/olfaction_phenotype1.31436234
45MP0004270_analgesia1.31349651
46MP0002735_abnormal_chemical_nociception1.30880088
47MP0005386_behavior/neurological_phenoty1.29335016
48MP0004924_abnormal_behavior1.29335016
49MP0000647_abnormal_sebaceous_gland1.26015539
50MP0005174_abnormal_tail_pigmentation1.25439616
51MP0002572_abnormal_emotion/affect_behav1.22641423
52MP0002734_abnormal_mechanical_nocicepti1.21478797
53MP0003890_abnormal_embryonic-extraembry1.20484612
54MP0004142_abnormal_muscle_tone1.19249762
55MP0005248_abnormal_Harderian_gland1.18987623
56MP0000631_abnormal_neuroendocrine_gland1.18747248
57MP0002938_white_spotting1.17757199
58MP0005646_abnormal_pituitary_gland1.17092489
59MP0002184_abnormal_innervation1.14432201
60MP0003635_abnormal_synaptic_transmissio1.13172861
61MP0001970_abnormal_pain_threshold1.12480250
62MP0003718_maternal_effect1.12373410
63MP0002067_abnormal_sensory_capabilities1.11139843
64MP0002095_abnormal_skin_pigmentation1.09917833
65MP0005187_abnormal_penis_morphology1.09447496
66MP0002063_abnormal_learning/memory/cond1.07285920
67MP0001986_abnormal_taste_sensitivity1.07151300
68MP0002909_abnormal_adrenal_gland1.05295068
69MP0001501_abnormal_sleep_pattern1.05015588
70MP0005195_abnormal_posterior_eye1.03891288
71MP0002752_abnormal_somatic_nervous1.02045757
72MP0004134_abnormal_chest_morphology0.99040875
73MP0001293_anophthalmia0.98396576
74MP0001324_abnormal_eye_pigmentation0.97019588
75MP0002733_abnormal_thermal_nociception0.95439025
76MP0000516_abnormal_urinary_system0.95041042
77MP0005367_renal/urinary_system_phenotyp0.95041042
78MP0002064_seizures0.94802423
79MP0000015_abnormal_ear_pigmentation0.94556352
80MP0002233_abnormal_nose_morphology0.93958761
81MP0002876_abnormal_thyroid_physiology0.93661238
82MP0003252_abnormal_bile_duct0.93215765
83MP0003698_abnormal_male_reproductive0.93111004
84MP0001764_abnormal_homeostasis0.92435836
85MP0000955_abnormal_spinal_cord0.91961728
86MP0001929_abnormal_gametogenesis0.91640399
87MP0005171_absent_coat_pigmentation0.91445778
88MP0001502_abnormal_circadian_rhythm0.90963937
89MP0002882_abnormal_neuron_morphology0.89920856
90MP0002160_abnormal_reproductive_system0.89494265
91MP0003646_muscle_fatigue0.88605174
92MP0008872_abnormal_physiological_respon0.88534187
93MP0000383_abnormal_hair_follicle0.87858669
94MP0003136_yellow_coat_color0.86563996
95MP0006054_spinal_hemorrhage0.86107365
96MP0010386_abnormal_urinary_bladder0.85960694
97MP0001905_abnormal_dopamine_level0.85349111
98MP0005391_vision/eye_phenotype0.83115573
99MP0004043_abnormal_pH_regulation0.81736738
100MP0010678_abnormal_skin_adnexa0.80646323

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.68307995
2Abnormality of midbrain morphology (HP:0002418)3.54759391
3Molar tooth sign on MRI (HP:0002419)3.54759391
4Medial flaring of the eyebrow (HP:0010747)3.42787658
5Pancreatic fibrosis (HP:0100732)3.40685581
6Type II lissencephaly (HP:0007260)3.28436317
7Hyperventilation (HP:0002883)3.26147617
8True hermaphroditism (HP:0010459)3.12195327
9Nephronophthisis (HP:0000090)3.11386670
10Chronic hepatic failure (HP:0100626)3.11266445
11Gait imbalance (HP:0002141)3.02127474
12Congenital primary aphakia (HP:0007707)2.95082782
13Lissencephaly (HP:0001339)2.78208511
14Cerebellar dysplasia (HP:0007033)2.72427373
15Nephrogenic diabetes insipidus (HP:0009806)2.70836661
16Abnormality of the renal cortex (HP:0011035)2.69097982
17Abnormality of the renal medulla (HP:0100957)2.67468023
18Congenital stationary night blindness (HP:0007642)2.66906467
19Genital tract atresia (HP:0001827)2.65860619
20Hepatoblastoma (HP:0002884)2.62793130
21Drooling (HP:0002307)2.57234929
22Abolished electroretinogram (ERG) (HP:0000550)2.50675742
23Retinal dysplasia (HP:0007973)2.50538912
24Pachygyria (HP:0001302)2.50139388
25Absent speech (HP:0001344)2.49537909
26Protruding tongue (HP:0010808)2.47836770
27Vaginal atresia (HP:0000148)2.47110738
28Renal cortical cysts (HP:0000803)2.41637147
29Tubular atrophy (HP:0000092)2.40808751
30Attenuation of retinal blood vessels (HP:0007843)2.39519578
31Intestinal atresia (HP:0011100)2.39175062
32Volvulus (HP:0002580)2.33455785
33Excessive salivation (HP:0003781)2.33302802
34Inability to walk (HP:0002540)2.32834154
35Hypothermia (HP:0002045)2.29696188
36Ketoacidosis (HP:0001993)2.28082222
37Keratoconus (HP:0000563)2.27654455
38Increased corneal curvature (HP:0100692)2.27654455
39Febrile seizures (HP:0002373)2.23589542
40Broad-based gait (HP:0002136)2.22186272
41Postaxial hand polydactyly (HP:0001162)2.17839515
42Optic nerve hypoplasia (HP:0000609)2.14204798
43Hemiparesis (HP:0001269)2.13876937
44Abnormality of the labia minora (HP:0012880)2.12328355
45Amyotrophic lateral sclerosis (HP:0007354)2.12135499
463-Methylglutaconic aciduria (HP:0003535)2.10867384
47Agitation (HP:0000713)2.07629118
48Postaxial foot polydactyly (HP:0001830)2.07221781
49Neoplasm of the adrenal cortex (HP:0100641)2.06010357
50Cystic liver disease (HP:0006706)2.05076805
51Poor coordination (HP:0002370)2.04632687
52Aplasia/Hypoplasia of the tongue (HP:0010295)2.04342433
53Abnormality of the astrocytes (HP:0100707)2.01956259
54Astrocytoma (HP:0009592)2.01956259
55Hypsarrhythmia (HP:0002521)1.99621099
56Progressive macrocephaly (HP:0004481)1.99500680
57Adrenal hypoplasia (HP:0000835)1.99259605
58Tented upper lip vermilion (HP:0010804)1.99073811
59Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97944003
60Progressive inability to walk (HP:0002505)1.96436764
61Abnormal rod and cone electroretinograms (HP:0008323)1.96130272
62Aplasia/Hypoplasia of the tibia (HP:0005772)1.95302889
63EEG with generalized epileptiform discharges (HP:0011198)1.90910943
64Absent/shortened dynein arms (HP:0200106)1.90626906
65Dynein arm defect of respiratory motile cilia (HP:0012255)1.90626906
66Sclerocornea (HP:0000647)1.87401964
67Anencephaly (HP:0002323)1.87079838
68Narrow forehead (HP:0000341)1.86642265
69Epileptiform EEG discharges (HP:0011182)1.85976571
70Glioma (HP:0009733)1.85191447
71Bony spicule pigmentary retinopathy (HP:0007737)1.84101812
72Gaze-evoked nystagmus (HP:0000640)1.83877755
73Focal seizures (HP:0007359)1.83809517
74Abnormal drinking behavior (HP:0030082)1.83024920
75Polydipsia (HP:0001959)1.83024920
76Large for gestational age (HP:0001520)1.82595962
77Pendular nystagmus (HP:0012043)1.82437939
78Polyphagia (HP:0002591)1.81608347
79Oligodactyly (hands) (HP:0001180)1.80749918
80Methylmalonic acidemia (HP:0002912)1.80401131
81Septo-optic dysplasia (HP:0100842)1.80285985
82Acute necrotizing encephalopathy (HP:0006965)1.79447345
83Dyskinesia (HP:0100660)1.78265024
84Congenital hepatic fibrosis (HP:0002612)1.78004522
85Specific learning disability (HP:0001328)1.76631637
86Exotropia (HP:0000577)1.75623304
87Growth hormone deficiency (HP:0000824)1.75616029
88Dialeptic seizures (HP:0011146)1.75543416
89Dandy-Walker malformation (HP:0001305)1.75469782
90Hypomagnesemia (HP:0002917)1.75125810
91Abnormality of macular pigmentation (HP:0008002)1.71878586
92Astigmatism (HP:0000483)1.71441562
93Male pseudohermaphroditism (HP:0000037)1.71329147
94Limb hypertonia (HP:0002509)1.70726001
95Ketosis (HP:0001946)1.69979917
96Prominent nasal bridge (HP:0000426)1.69480958
97Tubulointerstitial nephritis (HP:0001970)1.68471166
98Increased CSF lactate (HP:0002490)1.67739569
99Abnormality of the pons (HP:0007361)1.67500928
100Broad alveolar ridges (HP:0000187)1.65775432

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.93412016
2CASK3.36466776
3WNK33.22807712
4TRIM283.03036564
5MAP3K42.98304695
6TNIK2.77151684
7MAP4K22.62924933
8EPHA42.62650600
9BCR2.48245203
10MARK12.37076144
11PNCK2.15108363
12MAPK131.96511719
13MAP2K71.95360677
14ADRBK21.91502383
15ERBB31.88334202
16ACVR1B1.74357823
17BMPR1B1.73434205
18PINK11.70720884
19STK38L1.70372611
20EPHA31.63592690
21GRK11.48570632
22CSNK1G21.36830165
23CSNK1G11.35902924
24PAK31.30929141
25DYRK21.30390396
26PLK21.27729883
27INSRR1.27425735
28NME11.26469968
29NUAK11.25430737
30MKNK21.21126733
31NTRK31.16757463
32CSNK1G31.14842974
33FGFR21.14239674
34MINK11.04613272
35SRPK11.02698900
36PRKCG0.97879267
37TAOK30.97825260
38CSNK1A1L0.97778709
39PRKCE0.91607589
40STK390.89022488
41MKNK10.85810889
42MAP2K60.85071631
43ZAK0.85014694
44FER0.85006070
45VRK10.84207310
46PHKG20.83699944
47PHKG10.83699944
48SIK30.83041424
49OXSR10.81255123
50WNK40.77669880
51MAP2K40.72925857
52PLK30.69335650
53EIF2AK30.69108409
54TXK0.67591141
55NTRK20.65518462
56SGK20.64655434
57YES10.64581075
58ADRBK10.62649249
59MARK30.57095474
60WEE10.55904268
61TIE10.54126250
62TEC0.53197269
63CAMK2A0.52020762
64PIK3CA0.51715935
65PTK2B0.50076076
66SGK2230.49056318
67SGK4940.49056318
68PLK40.49032636
69PKN10.47812877
70STK160.47781034
71DAPK20.47324100
72STK380.47076140
73DYRK30.44711251
74DYRK1A0.44238971
75NLK0.43959404
76CSNK1D0.43603276
77STK110.43536254
78CAMKK20.42640421
79ATM0.41338086
80PLK10.41307836
81PRKACA0.41036178
82AKT30.40588301
83PRKCQ0.40437277
84RPS6KA40.39211275
85CDK50.37815242
86CSNK1A10.37581712
87PRKCZ0.36764414
88CAMK1G0.35760577
89TGFBR20.35440956
90TGFBR10.35399063
91GRK70.33813175
92ERBB20.32565533
93CCNB10.32109187
94STK30.31722543
95MST40.30889609
96BCKDK0.28834138
97SIK20.27853821
98PRKACB0.27470381
99PRKG10.27153296
100CAMK2D0.26166795

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.60236884
2Protein export_Homo sapiens_hsa030603.35667627
3Butanoate metabolism_Homo sapiens_hsa006502.81452957
4Phototransduction_Homo sapiens_hsa047442.78421561
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.75887912
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.72245108
7Nicotine addiction_Homo sapiens_hsa050332.70628505
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.55358885
9Maturity onset diabetes of the young_Homo sapiens_hsa049502.48414010
10Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.09932178
11Fanconi anemia pathway_Homo sapiens_hsa034602.04858837
12Basal transcription factors_Homo sapiens_hsa030221.96926183
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.82138343
14Ether lipid metabolism_Homo sapiens_hsa005651.81911870
15Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.78845541
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.77065121
17Collecting duct acid secretion_Homo sapiens_hsa049661.75193082
18Taste transduction_Homo sapiens_hsa047421.74303337
19Propanoate metabolism_Homo sapiens_hsa006401.71693913
20Linoleic acid metabolism_Homo sapiens_hsa005911.68526119
21Selenocompound metabolism_Homo sapiens_hsa004501.58116428
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.53705375
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.51625047
24Oxidative phosphorylation_Homo sapiens_hsa001901.49274787
25Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.44821794
26Steroid biosynthesis_Homo sapiens_hsa001001.44559453
27Non-homologous end-joining_Homo sapiens_hsa034501.38781506
28RNA degradation_Homo sapiens_hsa030181.38405630
29Regulation of autophagy_Homo sapiens_hsa041401.36019316
30Morphine addiction_Homo sapiens_hsa050321.35466867
31Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.35448861
32Tryptophan metabolism_Homo sapiens_hsa003801.29062637
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.28068777
34Olfactory transduction_Homo sapiens_hsa047401.27744656
35Circadian entrainment_Homo sapiens_hsa047131.26521613
36Caffeine metabolism_Homo sapiens_hsa002321.26345950
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.22782325
38Peroxisome_Homo sapiens_hsa041461.20812941
39Glutamatergic synapse_Homo sapiens_hsa047241.19613109
40GABAergic synapse_Homo sapiens_hsa047271.18141024
41Circadian rhythm_Homo sapiens_hsa047101.15802009
42RNA polymerase_Homo sapiens_hsa030201.11253376
43ABC transporters_Homo sapiens_hsa020101.07371346
44Nitrogen metabolism_Homo sapiens_hsa009101.07023578
45Dopaminergic synapse_Homo sapiens_hsa047281.04894297
46Insulin secretion_Homo sapiens_hsa049111.00540965
47Dorso-ventral axis formation_Homo sapiens_hsa043200.99248182
48Homologous recombination_Homo sapiens_hsa034400.96645917
49Parkinsons disease_Homo sapiens_hsa050120.90500328
50Axon guidance_Homo sapiens_hsa043600.89785211
51Sulfur metabolism_Homo sapiens_hsa009200.89273923
52Cocaine addiction_Homo sapiens_hsa050300.85235817
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.81803099
54Amphetamine addiction_Homo sapiens_hsa050310.81563347
55beta-Alanine metabolism_Homo sapiens_hsa004100.77224178
56Long-term depression_Homo sapiens_hsa047300.76995405
57Serotonergic synapse_Homo sapiens_hsa047260.74613076
58Ovarian steroidogenesis_Homo sapiens_hsa049130.73179771
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71978054
60Purine metabolism_Homo sapiens_hsa002300.65858931
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65193134
62Retinol metabolism_Homo sapiens_hsa008300.64774999
63Renin secretion_Homo sapiens_hsa049240.62090460
64Huntingtons disease_Homo sapiens_hsa050160.61326748
65Fatty acid elongation_Homo sapiens_hsa000620.61254740
66Chemical carcinogenesis_Homo sapiens_hsa052040.60472040
67Hedgehog signaling pathway_Homo sapiens_hsa043400.59529611
68Glycerolipid metabolism_Homo sapiens_hsa005610.59274111
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.55506055
70Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54580979
71Synaptic vesicle cycle_Homo sapiens_hsa047210.54119324
72Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53395151
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52845377
74Metabolic pathways_Homo sapiens_hsa011000.51604613
75Salivary secretion_Homo sapiens_hsa049700.48286888
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47643088
77Alzheimers disease_Homo sapiens_hsa050100.46994180
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.46541163
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.44530002
80Oocyte meiosis_Homo sapiens_hsa041140.42512807
81Fatty acid metabolism_Homo sapiens_hsa012120.42270436
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41767870
83Arachidonic acid metabolism_Homo sapiens_hsa005900.41665080
84Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.41401726
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40633360
86Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40613097
87Calcium signaling pathway_Homo sapiens_hsa040200.40478568
88RNA transport_Homo sapiens_hsa030130.40153285
89Sphingolipid metabolism_Homo sapiens_hsa006000.39164023
90TGF-beta signaling pathway_Homo sapiens_hsa043500.37509965
91Pyrimidine metabolism_Homo sapiens_hsa002400.36654317
92Type I diabetes mellitus_Homo sapiens_hsa049400.36630820
93Type II diabetes mellitus_Homo sapiens_hsa049300.34981356
94Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34366418
95p53 signaling pathway_Homo sapiens_hsa041150.32830650
96Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.32054809
97Cholinergic synapse_Homo sapiens_hsa047250.31038666
98Nucleotide excision repair_Homo sapiens_hsa034200.30071618
99Fat digestion and absorption_Homo sapiens_hsa049750.29781688
100cAMP signaling pathway_Homo sapiens_hsa040240.28546567

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