ZNF596

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.64132014
2cellular ketone body metabolic process (GO:0046950)4.54989390
3respiratory chain complex IV assembly (GO:0008535)4.24926446
4regulation of hexokinase activity (GO:1903299)4.11838601
5regulation of glucokinase activity (GO:0033131)4.11838601
6ketone body metabolic process (GO:1902224)4.06566871
7cytochrome complex assembly (GO:0017004)4.01383126
8protein complex biogenesis (GO:0070271)3.90889406
9single strand break repair (GO:0000012)3.85958029
10fucose catabolic process (GO:0019317)3.84645945
11L-fucose metabolic process (GO:0042354)3.84645945
12L-fucose catabolic process (GO:0042355)3.84645945
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.82136898
14behavioral response to nicotine (GO:0035095)3.77924857
15negative regulation of neurological system process (GO:0031645)3.73468004
16water-soluble vitamin biosynthetic process (GO:0042364)3.69823987
17regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.69025713
18mitochondrial respiratory chain complex assembly (GO:0033108)3.61382932
19negative regulation of mast cell activation (GO:0033004)3.60559585
20piRNA metabolic process (GO:0034587)3.54841245
21mitochondrial respiratory chain complex I assembly (GO:0032981)3.50602123
22NADH dehydrogenase complex assembly (GO:0010257)3.50602123
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.50602123
24protein prenylation (GO:0018342)3.47679937
25prenylation (GO:0097354)3.47679937
26epithelial cilium movement (GO:0003351)3.36802071
27axoneme assembly (GO:0035082)3.34774656
28kidney morphogenesis (GO:0060993)3.32743974
29detection of light stimulus involved in sensory perception (GO:0050962)3.29873969
30detection of light stimulus involved in visual perception (GO:0050908)3.29873969
31detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.21297269
32regulation of meiosis I (GO:0060631)3.19849857
33protein localization to cilium (GO:0061512)3.11503988
34rRNA catabolic process (GO:0016075)3.10036635
35DNA deamination (GO:0045006)3.05183491
36preassembly of GPI anchor in ER membrane (GO:0016254)2.99273194
37inositol phosphate catabolic process (GO:0071545)2.92810554
38DNA methylation involved in gamete generation (GO:0043046)2.92051083
39negative regulation of membrane potential (GO:0045837)2.91936438
40protein K11-linked deubiquitination (GO:0035871)2.89794638
41cilium organization (GO:0044782)2.86607290
42aggressive behavior (GO:0002118)2.86344552
43mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.84118851
44cilium assembly (GO:0042384)2.82729978
45regulation of action potential (GO:0098900)2.79756888
46neuronal action potential (GO:0019228)2.78772780
47cilium movement (GO:0003341)2.78607449
48peptidyl-histidine modification (GO:0018202)2.76394400
49protein-cofactor linkage (GO:0018065)2.72925249
50cilium or flagellum-dependent cell motility (GO:0001539)2.70765164
51photoreceptor cell maintenance (GO:0045494)2.69270177
52response to nitrosative stress (GO:0051409)2.66542697
53regulation of cilium movement (GO:0003352)2.65102848
54nonmotile primary cilium assembly (GO:0035058)2.63991167
55indolalkylamine metabolic process (GO:0006586)2.62608211
56regulation of rhodopsin mediated signaling pathway (GO:0022400)2.62108526
57rhodopsin mediated signaling pathway (GO:0016056)2.60181563
58reflex (GO:0060004)2.59631723
59thyroid hormone metabolic process (GO:0042403)2.59311219
60protein polyglutamylation (GO:0018095)2.57196959
61C4-dicarboxylate transport (GO:0015740)2.57073829
62inositol phosphate dephosphorylation (GO:0046855)2.56563265
63phosphorylated carbohydrate dephosphorylation (GO:0046838)2.56563265
64tryptophan catabolic process (GO:0006569)2.55937607
65indole-containing compound catabolic process (GO:0042436)2.55937607
66indolalkylamine catabolic process (GO:0046218)2.55937607
67neural tube formation (GO:0001841)2.55114562
68dentate gyrus development (GO:0021542)2.55025503
69GPI anchor metabolic process (GO:0006505)2.53359662
70negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.50900997
71cilium morphogenesis (GO:0060271)2.50633824
72behavioral response to ethanol (GO:0048149)2.50460082
73negative regulation of cytosolic calcium ion concentration (GO:0051481)2.48641770
74C-terminal protein amino acid modification (GO:0018410)2.48625468
75platelet dense granule organization (GO:0060155)2.48546557
76auditory receptor cell differentiation (GO:0042491)2.48327574
77polyol catabolic process (GO:0046174)2.48196015
78presynaptic membrane assembly (GO:0097105)2.48145160
79negative regulation of synaptic transmission, GABAergic (GO:0032229)2.47482113
80nitric oxide mediated signal transduction (GO:0007263)2.47453763
81anterograde synaptic vesicle transport (GO:0048490)2.47369936
82auditory receptor cell stereocilium organization (GO:0060088)2.46635540
83G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.46417061
84retinal cone cell development (GO:0046549)2.45817098
85startle response (GO:0001964)2.45000357
86cornea development in camera-type eye (GO:0061303)2.42658471
87regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.40427052
88positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.40427052
89centriole replication (GO:0007099)2.39049190
90auditory behavior (GO:0031223)2.38473790
91positive regulation of meiosis (GO:0045836)2.38193800
92prostate gland growth (GO:0060736)2.37966448
93sperm motility (GO:0030317)2.37745887
94regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.37520371
95positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.37520371
96protein import into peroxisome matrix (GO:0016558)2.36501906
97male meiosis (GO:0007140)2.36399396
98protein K6-linked ubiquitination (GO:0085020)2.35835165
99dopamine transport (GO:0015872)2.34235833
100seminiferous tubule development (GO:0072520)2.33093369

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* ZNF274_21170338_ChIP-Seq_K562_Hela3.44627231
2VDR_22108803_ChIP-Seq_LS180_Human3.28341277
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.26653505
4GBX2_23144817_ChIP-Seq_PC3_Human3.03449913
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.66118245
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.58247180
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.52991860
8IGF1R_20145208_ChIP-Seq_DFB_Human2.43537440
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.27562548
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.24295323
11FUS_26573619_Chip-Seq_HEK293_Human2.22000609
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.19265730
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14766916
14CTBP2_25329375_ChIP-Seq_LNCAP_Human2.12245503
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06457997
16EZH2_22144423_ChIP-Seq_EOC_Human2.06338369
17TAF15_26573619_Chip-Seq_HEK293_Human2.06067060
18EWS_26573619_Chip-Seq_HEK293_Human2.02567253
19P300_19829295_ChIP-Seq_ESCs_Human1.99019786
20ER_23166858_ChIP-Seq_MCF-7_Human1.92516590
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.89983171
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.71874773
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.71359901
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65717966
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.64324792
26EST1_17652178_ChIP-ChIP_JURKAT_Human1.62331945
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57171927
28* SMAD4_21799915_ChIP-Seq_A2780_Human1.56032563
29IRF1_19129219_ChIP-ChIP_H3396_Human1.55905226
30UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.54724537
31SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.54146105
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52970987
33CBP_20019798_ChIP-Seq_JUKART_Human1.52970987
34AR_25329375_ChIP-Seq_VCAP_Human1.51937955
35STAT3_23295773_ChIP-Seq_U87_Human1.51898480
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51772184
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.50943381
38MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.49901899
39TCF4_23295773_ChIP-Seq_U87_Human1.49191253
40TP53_22573176_ChIP-Seq_HFKS_Human1.49151923
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.48704391
42NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48583972
43BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.48428529
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42385664
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41955665
46BCAT_22108803_ChIP-Seq_LS180_Human1.40601513
47SALL1_21062744_ChIP-ChIP_HESCs_Human1.38395546
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37944032
49GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.37778620
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.36471744
51KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36299911
52NOTCH1_21737748_ChIP-Seq_TLL_Human1.35355513
53KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34129783
54AR_21572438_ChIP-Seq_LNCaP_Human1.32318280
55SUZ12_27294783_Chip-Seq_NPCs_Mouse1.31961296
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.31891785
57FOXA1_27270436_Chip-Seq_PROSTATE_Human1.31743494
58FOXA1_25329375_ChIP-Seq_VCAP_Human1.31743494
59OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31166029
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31107679
61EZH2_27294783_Chip-Seq_NPCs_Mouse1.30406564
62ELK1_19687146_ChIP-ChIP_HELA_Human1.30249311
63NANOG_19829295_ChIP-Seq_ESCs_Human1.28783544
64SOX2_19829295_ChIP-Seq_ESCs_Human1.28783544
65MYC_18940864_ChIP-ChIP_HL60_Human1.28143453
66RUNX2_22187159_ChIP-Seq_PCA_Human1.22375880
67PCGF2_27294783_Chip-Seq_NPCs_Mouse1.22260046
68TCF4_22108803_ChIP-Seq_LS180_Human1.22122119
69* VDR_23849224_ChIP-Seq_CD4+_Human1.21719066
70REST_21632747_ChIP-Seq_MESCs_Mouse1.21654554
71EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21615677
72AR_20517297_ChIP-Seq_VCAP_Human1.21098567
73FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20976145
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20027020
75FLI1_21867929_ChIP-Seq_TH2_Mouse1.17949599
76NFE2_27457419_Chip-Seq_LIVER_Mouse1.17703517
77BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15174557
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.12401837
79SMAD4_21741376_ChIP-Seq_EPCs_Human1.11642306
80ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11537347
81GATA3_21878914_ChIP-Seq_MCF-7_Human1.10755230
82CRX_20693478_ChIP-Seq_RETINA_Mouse1.10614989
83NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09906698
84TAL1_26923725_Chip-Seq_HPCs_Mouse1.09560770
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.09103940
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09034142
87NCOR_22424771_ChIP-Seq_293T_Human1.08853478
88CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.07881772
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.07731325
90RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05100677
91CDX2_22108803_ChIP-Seq_LS180_Human1.04311852
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04264285
93TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04264285
94SRF_21415370_ChIP-Seq_HL-1_Mouse1.01846915
95HOXB7_26014856_ChIP-Seq_BT474_Human1.01155903
96CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00915287
97OCT4_21477851_ChIP-Seq_ESCs_Mouse0.98974786
98P53_22387025_ChIP-Seq_ESCs_Mouse0.98740787
99RNF2_27304074_Chip-Seq_NSC_Mouse0.98121738
100NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.97762718

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color3.18824241
2MP0000372_irregular_coat_pigmentation3.05007292
3MP0006072_abnormal_retinal_apoptosis2.77319169
4MP0005645_abnormal_hypothalamus_physiol2.72647224
5MP0002876_abnormal_thyroid_physiology2.67062538
6MP0000569_abnormal_digit_pigmentation2.64007315
7MP0003195_calcinosis2.50687373
8MP0005551_abnormal_eye_electrophysiolog2.28977424
9MP0001986_abnormal_taste_sensitivity2.27916976
10MP0001501_abnormal_sleep_pattern2.27302719
11MP0008877_abnormal_DNA_methylation2.15481834
12MP0002938_white_spotting2.10814249
13MP0005174_abnormal_tail_pigmentation2.09741366
14MP0005253_abnormal_eye_physiology2.06829001
15MP0004885_abnormal_endolymph2.01424445
16MP0001984_abnormal_olfaction1.97450426
17MP0005646_abnormal_pituitary_gland1.92730490
18MP0004142_abnormal_muscle_tone1.89724535
19MP0003011_delayed_dark_adaptation1.86649368
20MP0003880_abnormal_central_pattern1.83679584
21MP0002163_abnormal_gland_morphology1.78266261
22MP0009046_muscle_twitch1.76840059
23MP0001968_abnormal_touch/_nociception1.75595046
24MP0002837_dystrophic_cardiac_calcinosis1.74049338
25MP0009745_abnormal_behavioral_response1.72545754
26MP0005367_renal/urinary_system_phenotyp1.71788560
27MP0000516_abnormal_urinary_system1.71788560
28MP0005379_endocrine/exocrine_gland_phen1.68872336
29MP0008995_early_reproductive_senescence1.64835942
30MP0005075_abnormal_melanosome_morpholog1.62432075
31MP0005084_abnormal_gallbladder_morpholo1.62191289
32MP0006292_abnormal_olfactory_placode1.57939864
33MP0000427_abnormal_hair_cycle1.57936007
34MP0002272_abnormal_nervous_system1.56796561
35MP0002095_abnormal_skin_pigmentation1.56390959
36MP0002102_abnormal_ear_morphology1.53965269
37MP0005187_abnormal_penis_morphology1.53480441
38MP0000015_abnormal_ear_pigmentation1.51527628
39MP0008058_abnormal_DNA_repair1.51450601
40MP0003122_maternal_imprinting1.50420366
41MP0008872_abnormal_physiological_respon1.49913553
42MP0004133_heterotaxia1.49456483
43MP0004147_increased_porphyrin_level1.48292969
44MP0002638_abnormal_pupillary_reflex1.47684833
45MP0004043_abnormal_pH_regulation1.43591628
46MP0008875_abnormal_xenobiotic_pharmacok1.43320971
47MP0000631_abnormal_neuroendocrine_gland1.42557543
48MP0002653_abnormal_ependyma_morphology1.38469731
49MP0002736_abnormal_nociception_after1.31189900
50MP0002064_seizures1.29935450
51MP0002928_abnormal_bile_duct1.29235815
52MP0002557_abnormal_social/conspecific_i1.28523496
53MP0000383_abnormal_hair_follicle1.27887817
54MP0002822_catalepsy1.25680358
55MP0002572_abnormal_emotion/affect_behav1.18139940
56MP0004742_abnormal_vestibular_system1.15177419
57MP0001905_abnormal_dopamine_level1.13857777
58MP0006276_abnormal_autonomic_nervous1.10848560
59MP0003718_maternal_effect1.09173308
60MP0005386_behavior/neurological_phenoty1.08742195
61MP0004924_abnormal_behavior1.08742195
62MP0010386_abnormal_urinary_bladder1.07443405
63MP0003787_abnormal_imprinting1.05915381
64MP0000538_abnormal_urinary_bladder1.03657230
65MP0003121_genomic_imprinting1.02553289
66MP0001486_abnormal_startle_reflex1.01722630
67MP0002733_abnormal_thermal_nociception1.01347570
68MP0005423_abnormal_somatic_nervous1.00889497
69MP0001970_abnormal_pain_threshold1.00775637
70MP0004215_abnormal_myocardial_fiber1.00665699
71MP0010678_abnormal_skin_adnexa1.00522574
72MP0002693_abnormal_pancreas_physiology1.00312012
73MP0002160_abnormal_reproductive_system0.98549937
74MP0002751_abnormal_autonomic_nervous0.98424982
75MP0005389_reproductive_system_phenotype0.97261753
76MP0001944_abnormal_pancreas_morphology0.96637310
77MP0003698_abnormal_male_reproductive0.96330054
78MP0003252_abnormal_bile_duct0.95000042
79MP0002067_abnormal_sensory_capabilities0.94374168
80MP0001929_abnormal_gametogenesis0.94322166
81MP0002229_neurodegeneration0.92182186
82MP0005085_abnormal_gallbladder_physiolo0.92066372
83MP0001502_abnormal_circadian_rhythm0.91981506
84MP0003646_muscle_fatigue0.90141470
85MP0001764_abnormal_homeostasis0.89695530
86MP0005410_abnormal_fertilization0.87321289
87MP0005220_abnormal_exocrine_pancreas0.85592303
88MP0009780_abnormal_chondrocyte_physiolo0.84975373
89MP0005195_abnormal_posterior_eye0.84308000
90MP0001529_abnormal_vocalization0.82916114
91MP0002735_abnormal_chemical_nociception0.81958310
92MP0000371_diluted_coat_color0.81677727
93MP0002210_abnormal_sex_determination0.81471903
94MP0001485_abnormal_pinna_reflex0.81348171
95MP0003633_abnormal_nervous_system0.80992351
96MP0003635_abnormal_synaptic_transmissio0.79205438
97MP0005332_abnormal_amino_acid0.78705355
98MP0006036_abnormal_mitochondrial_physio0.76414231
99MP0008775_abnormal_heart_ventricle0.76235322
100MP0002063_abnormal_learning/memory/cond0.75361563

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.92579067
2Pancreatic fibrosis (HP:0100732)3.89664539
3Molar tooth sign on MRI (HP:0002419)3.57639656
4Abnormality of midbrain morphology (HP:0002418)3.57639656
5Nephronophthisis (HP:0000090)3.57236550
6True hermaphroditism (HP:0010459)3.42655964
7Congenital stationary night blindness (HP:0007642)3.40287380
8Progressive macrocephaly (HP:0004481)3.38493757
9Thyroiditis (HP:0100646)3.38101948
10Acute necrotizing encephalopathy (HP:0006965)3.18933490
11Hyperventilation (HP:0002883)3.08656863
12Abnormality of the renal medulla (HP:0100957)3.07566703
13Medial flaring of the eyebrow (HP:0010747)3.02277395
14Type II lissencephaly (HP:0007260)3.01263378
15Methylmalonic acidemia (HP:0002912)2.96281877
16Attenuation of retinal blood vessels (HP:0007843)2.93608134
17Mitochondrial inheritance (HP:0001427)2.92951677
18Abnormality of the renal cortex (HP:0011035)2.88023651
19Absent speech (HP:0001344)2.82129123
20Hypothermia (HP:0002045)2.80420123
21Abolished electroretinogram (ERG) (HP:0000550)2.74672719
22Abnormal mitochondria in muscle tissue (HP:0008316)2.70432855
23Hemiparesis (HP:0001269)2.69503201
24Increased CSF lactate (HP:0002490)2.68588098
25Chronic hepatic failure (HP:0100626)2.67745113
26Acute encephalopathy (HP:0006846)2.56872549
27Tubular atrophy (HP:0000092)2.55408204
28Abnormal rod and cone electroretinograms (HP:0008323)2.52154032
29Abnormality of macular pigmentation (HP:0008002)2.46539773
30Hepatocellular necrosis (HP:0001404)2.41591488
31Ketoacidosis (HP:0001993)2.41257160
32Methylmalonic aciduria (HP:0012120)2.40696038
33Optic nerve hypoplasia (HP:0000609)2.40189693
34Dialeptic seizures (HP:0011146)2.39265447
35Severe combined immunodeficiency (HP:0004430)2.37012953
36Cystic liver disease (HP:0006706)2.36242342
37Pendular nystagmus (HP:0012043)2.34263069
38Abnormal drinking behavior (HP:0030082)2.33007566
39Polydipsia (HP:0001959)2.33007566
40Renal cortical cysts (HP:0000803)2.32871365
41Hepatic necrosis (HP:0002605)2.29301313
42Gait imbalance (HP:0002141)2.25491414
43Congenital sensorineural hearing impairment (HP:0008527)2.21921604
44Congenital primary aphakia (HP:0007707)2.19509110
45Nephrogenic diabetes insipidus (HP:0009806)2.19297254
46Abnormality of vitamin B metabolism (HP:0004340)2.18764401
47Progressive cerebellar ataxia (HP:0002073)2.16924117
48Optic disc pallor (HP:0000543)2.16162439
49Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.16040959
50Abnormal biliary tract physiology (HP:0012439)2.15341230
51Bile duct proliferation (HP:0001408)2.15341230
52Cerebellar dysplasia (HP:0007033)2.15140355
53Focal motor seizures (HP:0011153)2.14612635
54Furrowed tongue (HP:0000221)2.13425751
55Aplasia/Hypoplasia of the fovea (HP:0008060)2.09924221
56Hypoplasia of the fovea (HP:0007750)2.09924221
57Congenital hepatic fibrosis (HP:0002612)2.09686135
58Gaze-evoked nystagmus (HP:0000640)2.09401609
59Decreased electroretinogram (ERG) amplitude (HP:0000654)2.07492502
60Large for gestational age (HP:0001520)2.07380137
61Inability to walk (HP:0002540)2.07238680
62Sclerocornea (HP:0000647)2.07178152
63Hypoplasia of the pons (HP:0012110)2.07143600
64Decreased central vision (HP:0007663)2.07022870
65Dynein arm defect of respiratory motile cilia (HP:0012255)2.06082090
66Absent/shortened dynein arms (HP:0200106)2.06082090
67Fair hair (HP:0002286)2.05624611
68Abnormality of the fovea (HP:0000493)2.04758092
69Aplasia/Hypoplasia of the tongue (HP:0010295)2.04154282
70Neoplasm of the adrenal cortex (HP:0100641)2.03799618
71Lipid accumulation in hepatocytes (HP:0006561)2.02633962
72Absent rod-and cone-mediated responses on ERG (HP:0007688)2.01610197
73Ketosis (HP:0001946)1.99605761
743-Methylglutaconic aciduria (HP:0003535)1.99276267
75Febrile seizures (HP:0002373)1.98877709
76Stomatitis (HP:0010280)1.96624278
77Postaxial foot polydactyly (HP:0001830)1.93372057
78Bony spicule pigmentary retinopathy (HP:0007737)1.92255399
79Atonic seizures (HP:0010819)1.92045364
80Focal seizures (HP:0007359)1.91958755
81Abnormality of the pons (HP:0007361)1.91760229
82Occipital encephalocele (HP:0002085)1.89971880
83Broad-based gait (HP:0002136)1.89456613
84Lissencephaly (HP:0001339)1.88725380
85Cutaneous melanoma (HP:0012056)1.88345936
86Absence seizures (HP:0002121)1.85317844
87Progressive inability to walk (HP:0002505)1.85159077
88Retinal dysplasia (HP:0007973)1.84397544
89Thyroid-stimulating hormone excess (HP:0002925)1.84275271
90Keratoconus (HP:0000563)1.83859340
91Increased corneal curvature (HP:0100692)1.83859340
92Concave nail (HP:0001598)1.83346344
93Abnormality of the vitamin B12 metabolism (HP:0004341)1.83117948
94Genital tract atresia (HP:0001827)1.82928598
95Severe muscular hypotonia (HP:0006829)1.81845581
96Intestinal atresia (HP:0011100)1.81157816
97Hypoproteinemia (HP:0003075)1.78401724
98Protruding tongue (HP:0010808)1.78075368
99Hamartoma of the eye (HP:0010568)1.77858042
100Abnormal respiratory epithelium morphology (HP:0012253)1.76666679

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK6.96656489
2CASK3.70020615
3PINK12.88769898
4BMPR1B2.74540256
5MAP4K22.39380055
6TAOK32.36263417
7MAPK132.35774115
8ADRBK22.28226136
9ZAK2.21802773
10FGFR22.16206684
11GRK11.92475671
12EIF2AK31.91924116
13STK38L1.84068913
14WNK31.82800361
15MAP3K41.81351488
16INSRR1.64685307
17WNK41.58217561
18TAOK11.57618086
19TLK11.54240301
20MAP2K71.49427985
21PHKG21.33095351
22PHKG11.33095351
23MKNK21.33019417
24OXSR11.26701294
25MST41.24384199
26NUAK11.20122330
27STK391.17324008
28PRKCE1.11379818
29CDK31.10833442
30ACVR1B1.09384773
31CSNK1G31.07927609
32BRSK21.04373662
33TXK1.02825641
34CSNK1G20.98227646
35CSNK1G10.97974429
36PAK30.96207362
37ERBB30.94830084
38PLK20.94459610
39MARK10.93184099
40TRPM70.87180768
41TRIM280.86535653
42DYRK20.85890640
43PKN10.84460684
44DAPK20.79184328
45CSNK1A1L0.77101304
46PTK2B0.75967108
47NTRK30.75384752
48ADRBK10.74810002
49VRK10.74439162
50EPHA40.73986649
51MKNK10.73219894
52OBSCN0.72701230
53AKT30.72502764
54PRKCG0.70383367
55IKBKB0.69643055
56STK110.68072160
57STK380.66452179
58BCKDK0.66286963
59EIF2AK10.65387240
60MAPKAPK30.64395389
61RPS6KA50.62284884
62MAP2K60.58081894
63PLK40.56013434
64FER0.55586012
65CSNK1D0.54774218
66UHMK10.54332139
67DYRK30.53220625
68TNIK0.52380339
69TEC0.51949950
70GRK70.51800013
71CAMK2A0.51704747
72TGFBR10.51404289
73PRKG10.50349313
74PIK3CA0.50115952
75EPHA30.47441901
76BCR0.47194610
77PIK3CG0.44546460
78PRKCQ0.43190854
79MUSK0.43168076
80CAMK40.43000067
81PLK30.42986212
82STK30.42953967
83FLT30.42304748
84CSNK1A10.40861593
85ATM0.40860849
86CAMK10.40648373
87PRKACA0.39782518
88KIT0.38607282
89CAMKK20.37068621
90PRKACB0.35458920
91CAMK2D0.35284260
92ERBB40.33836484
93MARK30.33428616
94NTRK20.30895635
95ITK0.30660700
96PRKCI0.30064933
97TNK20.29368301
98PNCK0.29065617
99TIE10.27627652
100IRAK10.27171884

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.08389923
2Butanoate metabolism_Homo sapiens_hsa006502.93216926
3Phototransduction_Homo sapiens_hsa047442.92324254
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.81680229
5Oxidative phosphorylation_Homo sapiens_hsa001902.69429929
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.57910505
7Non-homologous end-joining_Homo sapiens_hsa034502.48439727
8Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.46311829
9Protein export_Homo sapiens_hsa030602.27327171
10Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.23834931
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.04213957
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.90761415
13Parkinsons disease_Homo sapiens_hsa050121.88761546
14Nitrogen metabolism_Homo sapiens_hsa009101.86689651
15Linoleic acid metabolism_Homo sapiens_hsa005911.79045039
16Propanoate metabolism_Homo sapiens_hsa006401.74559005
17Collecting duct acid secretion_Homo sapiens_hsa049661.72281273
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.65906786
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65526315
20Folate biosynthesis_Homo sapiens_hsa007901.64648085
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.55908671
22Nicotine addiction_Homo sapiens_hsa050331.55281194
23Primary bile acid biosynthesis_Homo sapiens_hsa001201.53639828
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.48797057
25Taste transduction_Homo sapiens_hsa047421.46436314
26Peroxisome_Homo sapiens_hsa041461.45505567
27Caffeine metabolism_Homo sapiens_hsa002321.43898800
28Tryptophan metabolism_Homo sapiens_hsa003801.42438487
29Ether lipid metabolism_Homo sapiens_hsa005651.41885155
30RNA polymerase_Homo sapiens_hsa030201.41711941
31Olfactory transduction_Homo sapiens_hsa047401.39065433
32Basal transcription factors_Homo sapiens_hsa030221.32515482
33Selenocompound metabolism_Homo sapiens_hsa004501.29585106
34ABC transporters_Homo sapiens_hsa020101.27163547
35Fanconi anemia pathway_Homo sapiens_hsa034601.24998280
36Huntingtons disease_Homo sapiens_hsa050161.24056665
37Homologous recombination_Homo sapiens_hsa034401.23140047
38RNA degradation_Homo sapiens_hsa030181.22808483
39Alzheimers disease_Homo sapiens_hsa050101.15485909
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.12522769
41Insulin secretion_Homo sapiens_hsa049111.10776138
42Regulation of autophagy_Homo sapiens_hsa041401.06634253
43Chemical carcinogenesis_Homo sapiens_hsa052041.05611940
44Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.01320496
45Circadian entrainment_Homo sapiens_hsa047130.99680301
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.99153076
47Morphine addiction_Homo sapiens_hsa050320.97756508
48GABAergic synapse_Homo sapiens_hsa047270.97050560
49Cardiac muscle contraction_Homo sapiens_hsa042600.87738270
50Circadian rhythm_Homo sapiens_hsa047100.86170016
51Glutamatergic synapse_Homo sapiens_hsa047240.85273257
52SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84863230
53Vitamin B6 metabolism_Homo sapiens_hsa007500.84840398
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.84434365
55Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84185365
56Steroid biosynthesis_Homo sapiens_hsa001000.82213915
57Serotonergic synapse_Homo sapiens_hsa047260.81544246
58Sulfur metabolism_Homo sapiens_hsa009200.78976914
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.76805560
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.75639792
61Fatty acid metabolism_Homo sapiens_hsa012120.75142847
62Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.74270270
63Dorso-ventral axis formation_Homo sapiens_hsa043200.72166541
64Purine metabolism_Homo sapiens_hsa002300.70295344
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68956915
66Retinol metabolism_Homo sapiens_hsa008300.68364591
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.67344336
68Cocaine addiction_Homo sapiens_hsa050300.66795956
69Amphetamine addiction_Homo sapiens_hsa050310.66601912
70Dopaminergic synapse_Homo sapiens_hsa047280.66056102
71Metabolic pathways_Homo sapiens_hsa011000.65818601
72Sulfur relay system_Homo sapiens_hsa041220.65684788
73Type I diabetes mellitus_Homo sapiens_hsa049400.65086798
74Salivary secretion_Homo sapiens_hsa049700.64195377
75Ovarian steroidogenesis_Homo sapiens_hsa049130.63622784
76Glutathione metabolism_Homo sapiens_hsa004800.63082032
77One carbon pool by folate_Homo sapiens_hsa006700.62812114
78Intestinal immune network for IgA production_Homo sapiens_hsa046720.58701631
79Calcium signaling pathway_Homo sapiens_hsa040200.57076661
80Arachidonic acid metabolism_Homo sapiens_hsa005900.56991002
81Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.55326466
82beta-Alanine metabolism_Homo sapiens_hsa004100.53964188
83Fatty acid degradation_Homo sapiens_hsa000710.53541452
84Synaptic vesicle cycle_Homo sapiens_hsa047210.52944657
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51178527
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48597698
87Hedgehog signaling pathway_Homo sapiens_hsa043400.48418952
88Mineral absorption_Homo sapiens_hsa049780.43950562
89Renin secretion_Homo sapiens_hsa049240.43929620
90Nucleotide excision repair_Homo sapiens_hsa034200.42051074
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.39999045
92Asthma_Homo sapiens_hsa053100.39541764
93Pyrimidine metabolism_Homo sapiens_hsa002400.36491189
94Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35390337
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35013270
96Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.34760646
97Primary immunodeficiency_Homo sapiens_hsa053400.34677813
98cAMP signaling pathway_Homo sapiens_hsa040240.33260018
99Glycerolipid metabolism_Homo sapiens_hsa005610.32298816
100Proteasome_Homo sapiens_hsa030500.30298605

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »