ZNF571

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of mesoderm development (GO:2000380)6.45638635
2negative regulation of activin receptor signaling pathway (GO:0032926)5.94821310
3nodal signaling pathway (GO:0038092)5.87858700
4cell migration involved in gastrulation (GO:0042074)5.58010699
5regulation of meiosis I (GO:0060631)5.48697386
6anterior/posterior axis specification, embryo (GO:0008595)4.94169293
7regulation of activin receptor signaling pathway (GO:0032925)4.92744081
8regulation of timing of cell differentiation (GO:0048505)4.28195881
9sequestering of extracellular ligand from receptor (GO:0035581)4.14795933
10regulation of development, heterochronic (GO:0040034)4.04016107
11signal transduction involved in regulation of gene expression (GO:0023019)3.95617476
12DNA replication checkpoint (GO:0000076)3.95146808
13DNA double-strand break processing (GO:0000729)3.91906438
14piRNA metabolic process (GO:0034587)3.84662557
15mitochondrial fragmentation involved in apoptotic process (GO:0043653)3.70672405
16centriole replication (GO:0007099)3.67271526
17response to pheromone (GO:0019236)3.58970437
18somatic hypermutation of immunoglobulin genes (GO:0016446)3.58393515
19somatic diversification of immune receptors via somatic mutation (GO:0002566)3.58393515
20embryonic pattern specification (GO:0009880)3.57269315
21somite rostral/caudal axis specification (GO:0032525)3.42789852
22anterior/posterior axis specification (GO:0009948)3.37268407
23positive regulation of cardiac muscle cell proliferation (GO:0060045)3.37002841
24histone exchange (GO:0043486)3.35033019
25negative regulation of translation, ncRNA-mediated (GO:0040033)3.34921710
26regulation of translation, ncRNA-mediated (GO:0045974)3.34921710
27negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.34921710
28DNA methylation involved in gamete generation (GO:0043046)3.23673040
29regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.22542496
30mitotic G2/M transition checkpoint (GO:0044818)3.20522958
31synapsis (GO:0007129)3.17880015
32embryonic axis specification (GO:0000578)3.16568060
33L-ascorbic acid metabolic process (GO:0019852)3.16376341
34activin receptor signaling pathway (GO:0032924)3.13939729
35positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.10450727
36female gonad development (GO:0008585)3.09129097
37positive regulation of cardiac muscle tissue growth (GO:0055023)3.09034558
38monoubiquitinated protein deubiquitination (GO:0035520)3.08731536
39replication fork processing (GO:0031297)3.07759675
40positive regulation of gastrulation (GO:2000543)3.06510206
41primitive streak formation (GO:0090009)3.05571227
42regulation of acyl-CoA biosynthetic process (GO:0050812)3.03043645
43histone mRNA catabolic process (GO:0071044)3.00463014
44mitochondrial fission (GO:0000266)2.99789217
45photoreceptor cell maintenance (GO:0045494)2.99565932
46detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.99118011
47negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.98827526
48negative regulation of DNA recombination (GO:0045910)2.98820940
49gene silencing by RNA (GO:0031047)2.98459912
50protein K11-linked deubiquitination (GO:0035871)2.96421639
51positive regulation of histone H3-K4 methylation (GO:0051571)2.92897216
52epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.91927085
53RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.91814305
54chromatin remodeling at centromere (GO:0031055)2.88445330
55regulation of cofactor metabolic process (GO:0051193)2.86846702
56regulation of coenzyme metabolic process (GO:0051196)2.86846702
57negative regulation of DNA-dependent DNA replication (GO:2000104)2.85516335
58single strand break repair (GO:0000012)2.85475580
59platelet dense granule organization (GO:0060155)2.81757531
60postreplication repair (GO:0006301)2.79027929
61CENP-A containing nucleosome assembly (GO:0034080)2.78824911
62regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.74063300
63detection of light stimulus involved in sensory perception (GO:0050962)2.74009743
64detection of light stimulus involved in visual perception (GO:0050908)2.74009743
65retinal cone cell development (GO:0046549)2.70306061
66embryonic camera-type eye development (GO:0031076)2.70129452
67SMAD protein signal transduction (GO:0060395)2.70041384
68epithelial cilium movement (GO:0003351)2.68365023
69negative regulation of keratinocyte proliferation (GO:0010839)2.66513896
70regulation of hexokinase activity (GO:1903299)2.66136974
71regulation of glucokinase activity (GO:0033131)2.66136974
72regulation of posttranscriptional gene silencing (GO:0060147)2.64765167
73regulation of gene silencing by miRNA (GO:0060964)2.64765167
74regulation of gene silencing by RNA (GO:0060966)2.64765167
75response to BMP (GO:0071772)2.64670544
76cellular response to BMP stimulus (GO:0071773)2.64670544
77mannosylation (GO:0097502)2.64649624
78establishment of protein localization to Golgi (GO:0072600)2.64245948
79branching involved in labyrinthine layer morphogenesis (GO:0060670)2.63721971
80positive regulation of heart growth (GO:0060421)2.62974899
81reciprocal meiotic recombination (GO:0007131)2.62850176
82reciprocal DNA recombination (GO:0035825)2.62850176
83genitalia morphogenesis (GO:0035112)2.62685824
84double-strand break repair via homologous recombination (GO:0000724)2.61897417
85recombinational repair (GO:0000725)2.61482643
86tachykinin receptor signaling pathway (GO:0007217)2.60981562
87maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.60662537
88gastrulation (GO:0007369)2.60318111
89DNA demethylation (GO:0080111)2.60088170
90regulation of helicase activity (GO:0051095)2.59519790
91branched-chain amino acid catabolic process (GO:0009083)2.57063504
92regulation of acrosome reaction (GO:0060046)2.56809157
93kidney morphogenesis (GO:0060993)2.55491251
94negative regulation of androgen receptor signaling pathway (GO:0060766)2.54963711
95resolution of meiotic recombination intermediates (GO:0000712)2.54719505
96positive regulation of SMAD protein import into nucleus (GO:0060391)2.54359769
97regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.53180061
98regulation of mitotic spindle checkpoint (GO:1903504)2.53180061
99forebrain neuron differentiation (GO:0021879)2.52298618
100histone H2A acetylation (GO:0043968)2.52099338

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.68177143
2ZNF274_21170338_ChIP-Seq_K562_Hela3.04742443
3SALL1_21062744_ChIP-ChIP_HESCs_Human2.68340076
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.61724007
5VDR_22108803_ChIP-Seq_LS180_Human2.56921024
6IGF1R_20145208_ChIP-Seq_DFB_Human2.50079745
7FUS_26573619_Chip-Seq_HEK293_Human2.49649236
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.47960090
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.43859698
10GBX2_23144817_ChIP-Seq_PC3_Human2.40895638
11P300_19829295_ChIP-Seq_ESCs_Human2.37230296
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.33806452
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.25678260
14KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.21994284
15KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.21994284
16KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.21994284
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.15482434
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.15067606
19PCGF2_27294783_Chip-Seq_ESCs_Mouse2.10770559
20EWS_26573619_Chip-Seq_HEK293_Human2.02019499
21CTBP2_25329375_ChIP-Seq_LNCAP_Human1.97729323
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.93742704
23TAF15_26573619_Chip-Seq_HEK293_Human1.91918569
24SMAD3_21741376_ChIP-Seq_EPCs_Human1.91147705
25EZH2_22144423_ChIP-Seq_EOC_Human1.90748084
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.90453042
27SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.81668175
28SMAD3_21741376_ChIP-Seq_HESCs_Human1.79486242
29AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.78687474
30BCAT_22108803_ChIP-Seq_LS180_Human1.78415036
31KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.76031424
32ER_23166858_ChIP-Seq_MCF-7_Human1.64014497
33PCGF2_27294783_Chip-Seq_NPCs_Mouse1.62443359
34E2F4_17652178_ChIP-ChIP_JURKAT_Human1.59682779
35SMAD4_21741376_ChIP-Seq_HESCs_Human1.59093969
36UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.58734490
37EZH2_27294783_Chip-Seq_NPCs_Mouse1.54410854
38E2F7_22180533_ChIP-Seq_HELA_Human1.53554840
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.52703798
40SMAD4_21799915_ChIP-Seq_A2780_Human1.52468831
41GABP_17652178_ChIP-ChIP_JURKAT_Human1.52195060
42MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.52021070
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50382738
44CBP_20019798_ChIP-Seq_JUKART_Human1.50382738
45STAT3_23295773_ChIP-Seq_U87_Human1.48821348
46SUZ12_27294783_Chip-Seq_NPCs_Mouse1.47561118
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.46670233
48AR_25329375_ChIP-Seq_VCAP_Human1.45316443
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44180636
50TCF4_23295773_ChIP-Seq_U87_Human1.42506805
51SMAD4_21741376_ChIP-Seq_EPCs_Human1.42498829
52TP53_22573176_ChIP-Seq_HFKS_Human1.41800481
53NFE2_27457419_Chip-Seq_LIVER_Mouse1.40982610
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38786482
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38499144
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38067809
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38042366
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37583262
59TCF4_22108803_ChIP-Seq_LS180_Human1.37136074
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.33239435
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33239435
62CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.30586189
63* EST1_17652178_ChIP-ChIP_JURKAT_Human1.29934472
64SOX2_19829295_ChIP-Seq_ESCs_Human1.27218251
65NANOG_19829295_ChIP-Seq_ESCs_Human1.27218251
66OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26709298
67RUNX2_22187159_ChIP-Seq_PCA_Human1.24981597
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23364037
69CRX_20693478_ChIP-Seq_RETINA_Mouse1.22863081
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.20966729
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19062255
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.18715261
73ELK1_19687146_ChIP-ChIP_HELA_Human1.17578391
74RNF2_27304074_Chip-Seq_NSC_Mouse1.17561010
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17087463
76HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15751874
77FOXA1_21572438_ChIP-Seq_LNCaP_Human1.15695015
78TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15025250
79NANOG_18555785_Chip-Seq_ESCs_Mouse1.14475693
80MYC_18940864_ChIP-ChIP_HL60_Human1.14289101
81PRDM14_20953172_ChIP-Seq_ESCs_Human1.13478307
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13361315
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12084772
84PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11778888
85IRF1_19129219_ChIP-ChIP_H3396_Human1.11379917
86FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11327612
87VDR_23849224_ChIP-Seq_CD4+_Human1.09639106
88KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.09450564
89CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08315884
90CDX2_22108803_ChIP-Seq_LS180_Human1.06852023
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06668661
92E2F1_18555785_Chip-Seq_ESCs_Mouse1.05684905
93OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05682780
94EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05190022
95PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04411575
96SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.03918704
97P53_22387025_ChIP-Seq_ESCs_Mouse1.01127706
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00769399
99EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.97806320
100SUZ12_18555785_Chip-Seq_ESCs_Mouse0.96972345

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003890_abnormal_embryonic-extraembry6.02360068
2MP0006292_abnormal_olfactory_placode3.65123783
3MP0008877_abnormal_DNA_methylation3.50240362
4MP0004133_heterotaxia3.33674575
5MP0008057_abnormal_DNA_replication3.03280932
6MP0003718_maternal_effect2.50803837
7MP0010030_abnormal_orbit_morphology2.48892765
8MP0008058_abnormal_DNA_repair2.39673770
9MP0008004_abnormal_stomach_pH2.30309538
10MP0003119_abnormal_digestive_system2.22826016
11MP0005499_abnormal_olfactory_system2.11737302
12MP0005394_taste/olfaction_phenotype2.11737302
13MP0003283_abnormal_digestive_organ2.00110309
14MP0000372_irregular_coat_pigmentation1.97387244
15MP0003136_yellow_coat_color1.96072567
16MP0010094_abnormal_chromosome_stability1.90759053
17MP0002254_reproductive_system_inflammat1.87753724
18MP0002736_abnormal_nociception_after1.83856978
19MP0000516_abnormal_urinary_system1.82086940
20MP0005367_renal/urinary_system_phenotyp1.82086940
21MP0004264_abnormal_extraembryonic_tissu1.80841139
22MP0003880_abnormal_central_pattern1.80457889
23MP0003195_calcinosis1.69305681
24MP0005551_abnormal_eye_electrophysiolog1.67659772
25MP0008789_abnormal_olfactory_epithelium1.67509020
26MP0000569_abnormal_digit_pigmentation1.57922539
27MP0004147_increased_porphyrin_level1.55347658
28MP0008995_early_reproductive_senescence1.52461157
29MP0001984_abnormal_olfaction1.51626534
30MP0001968_abnormal_touch/_nociception1.47714060
31MP0005075_abnormal_melanosome_morpholog1.46583610
32MP0002234_abnormal_pharynx_morphology1.43295184
33MP0006072_abnormal_retinal_apoptosis1.42089009
34MP0002938_white_spotting1.37206539
35MP0001929_abnormal_gametogenesis1.36292318
36MP0003693_abnormal_embryo_hatching1.35900326
37MP0002102_abnormal_ear_morphology1.34897892
38MP0002233_abnormal_nose_morphology1.33252941
39MP0008872_abnormal_physiological_respon1.31583838
40MP0003567_abnormal_fetal_cardiomyocyte1.30441183
41MP0008932_abnormal_embryonic_tissue1.27355540
42MP0005174_abnormal_tail_pigmentation1.26372417
43MP0001293_anophthalmia1.21626107
44MP0001486_abnormal_startle_reflex1.20976012
45MP0002210_abnormal_sex_determination1.16617065
46MP0001286_abnormal_eye_development1.15734479
47MP0003698_abnormal_male_reproductive1.14058003
48MP0003941_abnormal_skin_development1.13810082
49MP0000631_abnormal_neuroendocrine_gland1.13218117
50MP0003787_abnormal_imprinting1.10738589
51MP0000653_abnormal_sex_gland1.09660504
52MP0005253_abnormal_eye_physiology1.08913908
53MP0003646_muscle_fatigue1.08257280
54MP0003137_abnormal_impulse_conducting1.07197460
55MP0003937_abnormal_limbs/digits/tail_de1.04574816
56MP0005645_abnormal_hypothalamus_physiol1.03645938
57MP0005646_abnormal_pituitary_gland1.01912635
58MP0001986_abnormal_taste_sensitivity1.01433913
59MP0005410_abnormal_fertilization1.00996182
60MP0000383_abnormal_hair_follicle1.00420984
61MP0000428_abnormal_craniofacial_morphol0.99734085
62MP0000427_abnormal_hair_cycle0.99508967
63MP0001764_abnormal_homeostasis0.99491208
64MP0001145_abnormal_male_reproductive0.99253556
65MP0003121_genomic_imprinting0.99133291
66MP0006276_abnormal_autonomic_nervous0.98031196
67MP0002735_abnormal_chemical_nociception0.96772641
68MP0002163_abnormal_gland_morphology0.94088981
69MP0000647_abnormal_sebaceous_gland0.93421841
70MP0002084_abnormal_developmental_patter0.92625856
71MP0003077_abnormal_cell_cycle0.92226203
72MP0005395_other_phenotype0.90403017
73MP0005084_abnormal_gallbladder_morpholo0.90242867
74MP0002138_abnormal_hepatobiliary_system0.89544882
75MP0003936_abnormal_reproductive_system0.87194379
76MP0003786_premature_aging0.86824434
77MP0002751_abnormal_autonomic_nervous0.86741897
78MP0001485_abnormal_pinna_reflex0.86241737
79MP0006035_abnormal_mitochondrial_morpho0.86240333
80MP0005187_abnormal_penis_morphology0.85673020
81MP0004957_abnormal_blastocyst_morpholog0.84126526
82MP0003943_abnormal_hepatobiliary_system0.83238655
83MP0002160_abnormal_reproductive_system0.82516752
84MP0005380_embryogenesis_phenotype0.81922155
85MP0001672_abnormal_embryogenesis/_devel0.81922155
86MP0004085_abnormal_heartbeat0.78646792
87MP0001324_abnormal_eye_pigmentation0.77235524
88MP0009046_muscle_twitch0.77157547
89MP0004215_abnormal_myocardial_fiber0.76535097
90MP0001188_hyperpigmentation0.76228900
91MP0001119_abnormal_female_reproductive0.75106865
92MP0002272_abnormal_nervous_system0.75019295
93MP0002638_abnormal_pupillary_reflex0.73148227
94MP0000470_abnormal_stomach_morphology0.72232526
95MP0002184_abnormal_innervation0.71728869
96MP0005195_abnormal_posterior_eye0.71426735
97MP0000049_abnormal_middle_ear0.71354089
98MP0002752_abnormal_somatic_nervous0.70539696
99MP0002572_abnormal_emotion/affect_behav0.70419699
100MP0009697_abnormal_copulation0.69719443

Predicted human phenotypes

RankGene SetZ-score
1Intestinal atresia (HP:0011100)6.47864174
2Oligodactyly (hands) (HP:0001180)6.00667967
3Double outlet right ventricle (HP:0001719)5.46639171
4Congenital malformation of the right heart (HP:0011723)5.46639171
5Aqueductal stenosis (HP:0002410)4.73820535
6Abnormality of the parathyroid morphology (HP:0011766)4.61715825
7Nuclear cataract (HP:0100018)4.47341096
8Esophageal atresia (HP:0002032)4.33805827
9Chin dimple (HP:0010751)4.04885428
10Oligodactyly (HP:0012165)4.03445344
11Labial hypoplasia (HP:0000066)3.77801485
12Progressive inability to walk (HP:0002505)3.61350392
13Absent radius (HP:0003974)3.60781307
14Abnormality of abdominal situs (HP:0011620)3.59622384
15Abdominal situs inversus (HP:0003363)3.59622384
16Hypoplastic female external genitalia (HP:0012815)3.49622040
17Absent forearm bone (HP:0003953)3.42729240
18Aplasia involving forearm bones (HP:0009822)3.42729240
19Gastrointestinal atresia (HP:0002589)3.34528714
20Anal stenosis (HP:0002025)3.32409574
21Anencephaly (HP:0002323)2.94650613
22Bifid tongue (HP:0010297)2.84866304
23Abnormality of the labia (HP:0000058)2.83361751
24Aplasia/Hypoplasia of the uvula (HP:0010293)2.79560938
25Cupped ear (HP:0000378)2.75208892
26Type II lissencephaly (HP:0007260)2.68452678
27Deep palmar crease (HP:0006191)2.67052112
28Anophthalmia (HP:0000528)2.67041592
29Horseshoe kidney (HP:0000085)2.66325059
30Down-sloping shoulders (HP:0200021)2.60515844
31Pancreatic cysts (HP:0001737)2.58924584
32Growth hormone deficiency (HP:0000824)2.58110251
33Mixed hearing impairment (HP:0000410)2.58100065
34Chromsome breakage (HP:0040012)2.53274831
35Chromosomal breakage induced by crosslinking agents (HP:0003221)2.50758247
36Abnormality of the labia minora (HP:0012880)2.46828492
37Abnormality of the duodenum (HP:0002246)2.42840855
38Abnormality of midbrain morphology (HP:0002418)2.38370001
39Molar tooth sign on MRI (HP:0002419)2.38370001
40Septo-optic dysplasia (HP:0100842)2.36496570
41Triphalangeal thumb (HP:0001199)2.33248450
42Cleft eyelid (HP:0000625)2.26101633
43Preaxial hand polydactyly (HP:0001177)2.24743262
44Optic nerve hypoplasia (HP:0000609)2.21414252
45Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.19723997
46Retinal dysplasia (HP:0007973)2.18703855
47Abnormality of chromosome stability (HP:0003220)2.14823738
48Hemivertebrae (HP:0002937)2.13048974
49Inability to walk (HP:0002540)2.12201342
50Gaze-evoked nystagmus (HP:0000640)2.08006777
51Aplasia/Hypoplasia of the tibia (HP:0005772)2.07327677
52Renal hypoplasia (HP:0000089)2.07007788
53Abnormality of alanine metabolism (HP:0010916)2.05481051
54Hyperalaninemia (HP:0003348)2.05481051
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.05481051
56Delayed puberty (HP:0000823)2.05439386
57Abnormality of the ileum (HP:0001549)2.05345430
58Hypoplastic labia majora (HP:0000059)2.05211918
59Meckel diverticulum (HP:0002245)2.04264982
60Medial flaring of the eyebrow (HP:0010747)2.02940915
61True hermaphroditism (HP:0010459)2.02703003
62Short thumb (HP:0009778)1.98609058
63Pancreatic fibrosis (HP:0100732)1.98082012
64Anosmia (HP:0000458)1.97579848
65Aplasia/Hypoplasia of the earlobes (HP:0009906)1.97415160
66Chronic hepatic failure (HP:0100626)1.97013613
67Hypoplasia of the ulna (HP:0003022)1.95615662
68Nephronophthisis (HP:0000090)1.93608572
69Anal atresia (HP:0002023)1.93437957
70Bifid scrotum (HP:0000048)1.90307536
71Stenosis of the external auditory canal (HP:0000402)1.89545368
72Genital tract atresia (HP:0001827)1.89473797
73Ependymoma (HP:0002888)1.87938314
74Aplasia/Hypoplasia of the ulna (HP:0006495)1.87728871
75Vaginal atresia (HP:0000148)1.85735011
76Abnormality of the labia majora (HP:0012881)1.85386712
77Abnormality of the antihelix (HP:0009738)1.84000572
78Dandy-Walker malformation (HP:0001305)1.83267970
79Colon cancer (HP:0003003)1.83063877
80Clubbing of toes (HP:0100760)1.81383235
81Abnormality of the renal cortex (HP:0011035)1.80476164
82Anterior segment dysgenesis (HP:0007700)1.77135707
83Attenuation of retinal blood vessels (HP:0007843)1.76480979
84Methylmalonic acidemia (HP:0002912)1.76367344
85Short middle phalanx of the 5th finger (HP:0004220)1.76350422
86Lissencephaly (HP:0001339)1.76065496
87Aplasia/Hypoplasia of the tongue (HP:0010295)1.75514861
88Volvulus (HP:0002580)1.75236801
89Renal cortical cysts (HP:0000803)1.74694394
90Congenital primary aphakia (HP:0007707)1.74573557
91Renal agenesis (HP:0000104)1.70239049
92Zonular cataract (HP:0010920)1.69910051
93Gait imbalance (HP:0002141)1.69720046
94Preaxial foot polydactyly (HP:0001841)1.67957416
95Aplasia/Hypoplasia of the sacrum (HP:0008517)1.67709088
96Abnormality of the renal medulla (HP:0100957)1.67609768
97Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.66794359
98Abnormality of the preputium (HP:0100587)1.65729569
99Nephrogenic diabetes insipidus (HP:0009806)1.65686044
100Abnormal connection of the cardiac segments (HP:0011545)1.64153824

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB44.97482084
2FRK4.65022039
3ACVR1B4.01223467
4BMPR1B3.51268659
5WNK33.27286860
6TRIM282.74497532
7PDK22.67837275
8PBK2.55736855
9TNIK2.29480725
10MAP4K22.24331228
11NUAK12.17868136
12MST42.17118669
13GRK12.12039899
14PINK11.75640877
15ZAK1.75327518
16MKNK21.62627541
17MAPK131.58478143
18PNCK1.52764519
19BRSK21.46379160
20BRD41.40740413
21MAP3K41.36967632
22WEE11.35230162
23PLK41.33867844
24TGFBR11.27484079
25FLT31.25859970
26EIF2AK31.15674001
27TAOK31.12711081
28INSRR1.11111194
29SRPK11.10944375
30CDK191.10590905
31ADRBK21.09557803
32NEK11.09552744
33MKNK11.05553486
34STK161.05019274
35CDC71.04227656
36STK38L1.00000882
37PLK20.93969287
38PLK30.91327845
39AKT30.88547947
40TNK20.88166913
41BCKDK0.87890748
42OXSR10.87526522
43BCR0.87170119
44PLK10.85285678
45TTK0.84725951
46STK390.82132881
47CASK0.81718160
48NLK0.81633196
49STK30.77308060
50PRKCE0.75346106
51FGFR20.70894540
52CSNK1G10.69065304
53ERBB30.68331968
54BUB10.68242961
55VRK10.65956899
56PAK30.65459565
57NEK60.65440161
58CAMK1G0.62019472
59ATR0.61799161
60OBSCN0.60667507
61MAP3K120.59762319
62SIK30.58128825
63MAP3K90.57785498
64ATM0.56732841
65CSNK1G20.55653134
66PRKCG0.55104282
67PRKD30.54693192
68CCNB10.53229305
69MELK0.52749012
70NME10.51494110
71KIT0.48805784
72TSSK60.48110592
73ADRBK10.48097187
74NTRK30.47833419
75CHEK20.46994769
76TEC0.46553466
77FGFR10.45888765
78LATS10.43293312
79PRKCI0.43203123
80CHEK10.42414308
81WNK40.39873797
82IRAK10.39334061
83CSNK1D0.37282095
84CSNK1A1L0.37094895
85EPHA40.36714210
86BRSK10.36278718
87CSNK1G30.35343744
88PKN10.34167358
89PRKG10.33337492
90MAP2K70.33076445
91NEK20.31685555
92DYRK20.31618170
93CSNK1A10.29601316
94CAMK2A0.28969991
95EIF2AK20.28535805
96CDK30.27882227
97MARK30.26658546
98PRKACB0.26409821
99FER0.26028528
100VRK20.25425627

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.15669621
2Homologous recombination_Homo sapiens_hsa034402.92999773
3Propanoate metabolism_Homo sapiens_hsa006402.77850247
4Phototransduction_Homo sapiens_hsa047442.66900823
5Non-homologous end-joining_Homo sapiens_hsa034502.63915462
6Basal transcription factors_Homo sapiens_hsa030222.63804606
7Mismatch repair_Homo sapiens_hsa034302.48529568
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.24084740
9Protein export_Homo sapiens_hsa030602.11835489
10Proteasome_Homo sapiens_hsa030502.08852954
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.06038820
12Butanoate metabolism_Homo sapiens_hsa006501.96751368
13RNA degradation_Homo sapiens_hsa030181.87954850
14Selenocompound metabolism_Homo sapiens_hsa004501.87603390
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.83211754
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.82092867
17Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.74703172
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.69084731
19Cysteine and methionine metabolism_Homo sapiens_hsa002701.64683752
20RNA polymerase_Homo sapiens_hsa030201.63851451
21Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61231548
22Base excision repair_Homo sapiens_hsa034101.58909283
23Nitrogen metabolism_Homo sapiens_hsa009101.53934044
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.48399539
25TGF-beta signaling pathway_Homo sapiens_hsa043501.47928935
26RNA transport_Homo sapiens_hsa030131.39087293
27Olfactory transduction_Homo sapiens_hsa047401.37259935
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.36846444
29Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.31990273
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.31179169
31DNA replication_Homo sapiens_hsa030301.28552167
32Linoleic acid metabolism_Homo sapiens_hsa005911.25913090
33Pyruvate metabolism_Homo sapiens_hsa006201.25371513
34beta-Alanine metabolism_Homo sapiens_hsa004101.25343838
35Nucleotide excision repair_Homo sapiens_hsa034201.23629410
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.22835601
37Oocyte meiosis_Homo sapiens_hsa041141.21951162
38Peroxisome_Homo sapiens_hsa041461.19027273
39Cell cycle_Homo sapiens_hsa041101.18975310
40Caffeine metabolism_Homo sapiens_hsa002321.18549482
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.14801136
42Fatty acid elongation_Homo sapiens_hsa000621.13647933
43Circadian rhythm_Homo sapiens_hsa047101.13609492
44Nicotine addiction_Homo sapiens_hsa050331.12623977
45Ether lipid metabolism_Homo sapiens_hsa005651.10590238
46Tryptophan metabolism_Homo sapiens_hsa003801.07654835
47ABC transporters_Homo sapiens_hsa020101.02272894
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97322323
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94573175
50Purine metabolism_Homo sapiens_hsa002300.93753428
51Calcium signaling pathway_Homo sapiens_hsa040200.92668211
52p53 signaling pathway_Homo sapiens_hsa041150.91553103
53Fatty acid metabolism_Homo sapiens_hsa012120.90539862
54Steroid biosynthesis_Homo sapiens_hsa001000.89316111
55Regulation of autophagy_Homo sapiens_hsa041400.86083660
56Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85968217
57mRNA surveillance pathway_Homo sapiens_hsa030150.83501048
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82266712
59Wnt signaling pathway_Homo sapiens_hsa043100.81038543
60Lysine degradation_Homo sapiens_hsa003100.80716327
61Taste transduction_Homo sapiens_hsa047420.79439558
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.79298539
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76859490
64Fatty acid degradation_Homo sapiens_hsa000710.76474164
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76075666
66One carbon pool by folate_Homo sapiens_hsa006700.72913130
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71238121
68Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69725613
69Retinol metabolism_Homo sapiens_hsa008300.69508502
70Dorso-ventral axis formation_Homo sapiens_hsa043200.67428564
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63265271
72Chemical carcinogenesis_Homo sapiens_hsa052040.61201433
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.60253199
74Parkinsons disease_Homo sapiens_hsa050120.60184181
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58078531
76Pyrimidine metabolism_Homo sapiens_hsa002400.57899226
77Metabolic pathways_Homo sapiens_hsa011000.56410036
78Huntingtons disease_Homo sapiens_hsa050160.53807832
79Fat digestion and absorption_Homo sapiens_hsa049750.53150800
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52552730
81Circadian entrainment_Homo sapiens_hsa047130.52368645
82Basal cell carcinoma_Homo sapiens_hsa052170.51960290
83Oxidative phosphorylation_Homo sapiens_hsa001900.51325171
84Arginine and proline metabolism_Homo sapiens_hsa003300.50615409
85Vitamin digestion and absorption_Homo sapiens_hsa049770.49778412
86Folate biosynthesis_Homo sapiens_hsa007900.48831377
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.46096850
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44366362
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44244291
90Hedgehog signaling pathway_Homo sapiens_hsa043400.43726514
91Ovarian steroidogenesis_Homo sapiens_hsa049130.43022491
92Hippo signaling pathway_Homo sapiens_hsa043900.42387116
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.39975409
94Arachidonic acid metabolism_Homo sapiens_hsa005900.39081923
95Morphine addiction_Homo sapiens_hsa050320.38610561
96Serotonergic synapse_Homo sapiens_hsa047260.38299825
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37260727
98Collecting duct acid secretion_Homo sapiens_hsa049660.32841276
99Glycerolipid metabolism_Homo sapiens_hsa005610.31701518
100cAMP signaling pathway_Homo sapiens_hsa040240.30324681

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »