ZNF232

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.13325470
2chaperone-mediated protein transport (GO:0072321)4.89824349
3establishment of protein localization to mitochondrial membrane (GO:0090151)4.49701771
4chromatin remodeling at centromere (GO:0031055)4.44573126
5energy coupled proton transport, down electrochemical gradient (GO:0015985)4.41233457
6ATP synthesis coupled proton transport (GO:0015986)4.41233457
7CENP-A containing nucleosome assembly (GO:0034080)4.17341772
8mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.98894226
9establishment of integrated proviral latency (GO:0075713)3.88204089
10protein complex biogenesis (GO:0070271)3.81532357
11cullin deneddylation (GO:0010388)3.79476610
12DNA double-strand break processing (GO:0000729)3.78806371
13proteasome assembly (GO:0043248)3.70693958
14respiratory electron transport chain (GO:0022904)3.66792737
15mitochondrial respiratory chain complex assembly (GO:0033108)3.66139282
16regulation of mitochondrial translation (GO:0070129)3.65022221
17respiratory chain complex IV assembly (GO:0008535)3.62550625
18protein deneddylation (GO:0000338)3.62032346
19electron transport chain (GO:0022900)3.59216221
20histone exchange (GO:0043486)3.58879391
21DNA damage response, detection of DNA damage (GO:0042769)3.57718570
22ribosomal small subunit assembly (GO:0000028)3.57589534
23negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.57013002
24termination of RNA polymerase III transcription (GO:0006386)3.56225525
25transcription elongation from RNA polymerase III promoter (GO:0006385)3.56225525
26mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.56082289
27mitochondrial respiratory chain complex I assembly (GO:0032981)3.56082289
28NADH dehydrogenase complex assembly (GO:0010257)3.56082289
29DNA strand elongation involved in DNA replication (GO:0006271)3.49696715
30protein neddylation (GO:0045116)3.47803642
31nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.44878253
32exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.39644502
33regulation of helicase activity (GO:0051095)3.37346354
34regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.33121766
35telomere maintenance via semi-conservative replication (GO:0032201)3.32774771
36somatic hypermutation of immunoglobulin genes (GO:0016446)3.31005843
37somatic diversification of immune receptors via somatic mutation (GO:0002566)3.31005843
38DNA strand elongation (GO:0022616)3.30621407
39DNA replication checkpoint (GO:0000076)3.30257288
40rRNA modification (GO:0000154)3.28074384
41DNA replication-independent nucleosome assembly (GO:0006336)3.26357915
42DNA replication-independent nucleosome organization (GO:0034724)3.26357915
43RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25927362
44tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25927362
45cytochrome complex assembly (GO:0017004)3.24771781
46negative regulation of ligase activity (GO:0051352)3.21087776
47negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.21087776
48spliceosomal snRNP assembly (GO:0000387)3.20573852
49DNA catabolic process, exonucleolytic (GO:0000738)3.20215945
50pseudouridine synthesis (GO:0001522)3.19465514
51maturation of SSU-rRNA (GO:0030490)3.18304693
52positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.17496002
53DNA ligation (GO:0006266)3.14784961
54resolution of meiotic recombination intermediates (GO:0000712)3.13106985
55anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.12422889
56replication fork processing (GO:0031297)3.08425448
57regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.06938463
58regulation of mitotic spindle checkpoint (GO:1903504)3.06938463
59protein targeting to mitochondrion (GO:0006626)3.05986781
60establishment of viral latency (GO:0019043)3.02891552
61water-soluble vitamin biosynthetic process (GO:0042364)3.01803057
62establishment of protein localization to mitochondrion (GO:0072655)2.96682958
63mitotic metaphase plate congression (GO:0007080)2.94123007
64protein localization to mitochondrion (GO:0070585)2.93937128
65purine nucleobase biosynthetic process (GO:0009113)2.92850243
66regulation of cellular amino acid metabolic process (GO:0006521)2.83991675
67translational termination (GO:0006415)2.83294498
68nucleotide-excision repair, DNA gap filling (GO:0006297)2.82952531
69mismatch repair (GO:0006298)2.82717253
70positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.81803262
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.78942547
72viral transcription (GO:0019083)2.78707634
73nucleobase biosynthetic process (GO:0046112)2.78130859
74signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.77892549
75signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.77892549
76signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.77892549
77transcription-coupled nucleotide-excision repair (GO:0006283)2.76307833
78kinetochore assembly (GO:0051382)2.76099796
79L-serine metabolic process (GO:0006563)2.76055317
80protein K6-linked ubiquitination (GO:0085020)2.75971800
81translation (GO:0006412)2.75751934
82telomere maintenance via recombination (GO:0000722)2.73654375
83negative regulation of DNA recombination (GO:0045910)2.73630302
84cotranslational protein targeting to membrane (GO:0006613)2.73429526
85intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.73301543
86signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.73301543
87SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.72703598
88sequestering of actin monomers (GO:0042989)2.72314345
89synapsis (GO:0007129)2.71637289
90IMP biosynthetic process (GO:0006188)2.71055897
91metaphase plate congression (GO:0051310)2.70236845
92inner mitochondrial membrane organization (GO:0007007)2.69634558
93postreplication repair (GO:0006301)2.69126580
94signal transduction involved in cell cycle checkpoint (GO:0072395)2.68632225
95pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.68168092
96positive regulation of ligase activity (GO:0051351)2.68128284
97base-excision repair, AP site formation (GO:0006285)2.67829047
98histone mRNA metabolic process (GO:0008334)2.67703894
99ribosomal small subunit biogenesis (GO:0042274)2.66524209
100signal transduction involved in DNA integrity checkpoint (GO:0072401)2.66176045

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.83592917
2E2F7_22180533_ChIP-Seq_HELA_Human4.37342998
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.15459128
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.08270173
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.93296036
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.24003222
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.23714098
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.07220469
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.00290726
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.99195768
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.93952077
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.92593158
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.82106840
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.67878252
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.57079076
16ELK1_19687146_ChIP-ChIP_HELA_Human2.48767977
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47890228
18VDR_23849224_ChIP-Seq_CD4+_Human2.23398914
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.19485351
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.19126020
21MYC_18358816_ChIP-ChIP_MESCs_Mouse2.16018491
22ZNF274_21170338_ChIP-Seq_K562_Hela2.11326679
23FOXP3_21729870_ChIP-Seq_TREG_Human2.05809851
24THAP11_20581084_ChIP-Seq_MESCs_Mouse2.05003264
25MYC_19079543_ChIP-ChIP_MESCs_Mouse1.98624890
26YY1_21170310_ChIP-Seq_MESCs_Mouse1.87614541
27TTF2_22483619_ChIP-Seq_HELA_Human1.86054361
28SRF_21415370_ChIP-Seq_HL-1_Mouse1.84370012
29MYC_18940864_ChIP-ChIP_HL60_Human1.83052384
30FOXM1_23109430_ChIP-Seq_U2OS_Human1.77139185
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.75338126
32YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.74668110
33DCP1A_22483619_ChIP-Seq_HELA_Human1.74307395
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.73108655
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.72910827
36POU5F1_16153702_ChIP-ChIP_HESCs_Human1.72820160
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.72577371
38IGF1R_20145208_ChIP-Seq_DFB_Human1.71880597
39* GABP_19822575_ChIP-Seq_HepG2_Human1.71048025
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.70711590
41XRN2_22483619_ChIP-Seq_HELA_Human1.69161087
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.68932674
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67215744
44EWS_26573619_Chip-Seq_HEK293_Human1.64716336
45NELFA_20434984_ChIP-Seq_ESCs_Mouse1.64397645
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.61567956
47SOX2_16153702_ChIP-ChIP_HESCs_Human1.55678793
48VDR_22108803_ChIP-Seq_LS180_Human1.55344034
49MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.52893576
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.52679805
51NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.52127674
52FUS_26573619_Chip-Seq_HEK293_Human1.52087024
53ELF1_17652178_ChIP-ChIP_JURKAT_Human1.49474384
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.43081119
55NANOG_16153702_ChIP-ChIP_HESCs_Human1.39209525
56IRF1_19129219_ChIP-ChIP_H3396_Human1.37798078
57POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37084471
58MYCN_18555785_ChIP-Seq_MESCs_Mouse1.35441758
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.33488056
60CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.31838735
61KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.27234010
62MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.24748705
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.23233794
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.21433020
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.19858959
66SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.12285417
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10368250
68DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01463883
69P300_19829295_ChIP-Seq_ESCs_Human1.00126214
70CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99854480
71TP63_19390658_ChIP-ChIP_HaCaT_Human0.99704115
72AR_21909140_ChIP-Seq_LNCAP_Human0.98852473
73KDM5A_27292631_Chip-Seq_BREAST_Human0.98232048
74GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.97707016
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96698803
76EZH2_22144423_ChIP-Seq_EOC_Human0.95020246
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.94779045
78POU3F2_20337985_ChIP-ChIP_501MEL_Human0.94539007
79NANOG_18555785_ChIP-Seq_MESCs_Mouse0.92164624
80ELK1_22589737_ChIP-Seq_MCF10A_Human0.89389457
81* CTBP2_25329375_ChIP-Seq_LNCAP_Human0.88859175
82PCGF2_27294783_Chip-Seq_ESCs_Mouse0.87714890
83TP53_22573176_ChIP-Seq_HFKS_Human0.87561060
84FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.86807140
85TAF15_26573619_Chip-Seq_HEK293_Human0.84967915
86RBPJ_22232070_ChIP-Seq_NCS_Mouse0.84489395
87ZFP57_27257070_Chip-Seq_ESCs_Mouse0.83887999
88ZFX_18555785_ChIP-Seq_MESCs_Mouse0.83864756
89EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.83697761
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.81007856
91SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.80879693
92TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80778230
93GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80451402
94HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80249163
95CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.79235780
96SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.77702647
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.74238058
98TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.73685609
99KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.73445417
100POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.69125269

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair3.45165824
2MP0006292_abnormal_olfactory_placode3.34076644
3MP0008877_abnormal_DNA_methylation3.16934686
4MP0010094_abnormal_chromosome_stability3.03768503
5MP0003693_abnormal_embryo_hatching2.81275792
6MP0008789_abnormal_olfactory_epithelium2.64198376
7MP0002102_abnormal_ear_morphology2.44224856
8MP0004957_abnormal_blastocyst_morpholog2.42908473
9MP0003111_abnormal_nucleus_morphology2.23181757
10MP0005394_taste/olfaction_phenotype2.19167058
11MP0005499_abnormal_olfactory_system2.19167058
12MP0008932_abnormal_embryonic_tissue2.14884486
13MP0001529_abnormal_vocalization2.11844517
14MP0006072_abnormal_retinal_apoptosis2.08509026
15MP0002938_white_spotting2.07234879
16MP0001293_anophthalmia2.01070832
17MP0009379_abnormal_foot_pigmentation1.99992091
18MP0003136_yellow_coat_color1.98620605
19MP0003718_maternal_effect1.97031571
20MP0001188_hyperpigmentation1.91178641
21MP0003121_genomic_imprinting1.89190778
22MP0002653_abnormal_ependyma_morphology1.83004449
23MP0003077_abnormal_cell_cycle1.78426972
24MP0009697_abnormal_copulation1.74569415
25MP0004133_heterotaxia1.73540200
26MP0003941_abnormal_skin_development1.66680336
27MP0005084_abnormal_gallbladder_morpholo1.63282102
28MP0001984_abnormal_olfaction1.58876803
29MP0003880_abnormal_central_pattern1.58005315
30MP0003122_maternal_imprinting1.57166723
31MP0003787_abnormal_imprinting1.55999009
32MP0010030_abnormal_orbit_morphology1.53202846
33MP0003786_premature_aging1.42511574
34MP0008007_abnormal_cellular_replicative1.42428382
35MP0003567_abnormal_fetal_cardiomyocyte1.40622479
36MP0006276_abnormal_autonomic_nervous1.39297430
37MP0008057_abnormal_DNA_replication1.39068700
38MP0000049_abnormal_middle_ear1.38894674
39MP0006035_abnormal_mitochondrial_morpho1.38741047
40MP0003119_abnormal_digestive_system1.37655289
41MP0000631_abnormal_neuroendocrine_gland1.36242084
42MP0003890_abnormal_embryonic-extraembry1.36209608
43MP0008995_early_reproductive_senescence1.35611110
44MP0002751_abnormal_autonomic_nervous1.33112984
45MP0006036_abnormal_mitochondrial_physio1.29810456
46MP0005253_abnormal_eye_physiology1.26685743
47MP0002210_abnormal_sex_determination1.24342656
48MP0002638_abnormal_pupillary_reflex1.22554692
49MP0003123_paternal_imprinting1.21346502
50MP0003011_delayed_dark_adaptation1.21318487
51MP0003186_abnormal_redox_activity1.20750474
52MP0002233_abnormal_nose_morphology1.19914649
53MP0003937_abnormal_limbs/digits/tail_de1.18416395
54MP0005551_abnormal_eye_electrophysiolog1.15943472
55MP0001929_abnormal_gametogenesis1.14636706
56MP0001286_abnormal_eye_development1.14253315
57MP0000566_synostosis1.09068960
58MP0000778_abnormal_nervous_system1.08999033
59MP0000653_abnormal_sex_gland1.06535919
60MP0001145_abnormal_male_reproductive1.05390868
61MP0003938_abnormal_ear_development1.03240733
62MP0002234_abnormal_pharynx_morphology1.02398410
63MP0000372_irregular_coat_pigmentation1.01742457
64MP0002736_abnormal_nociception_after1.00965870
65MP0002822_catalepsy1.00733501
66MP0002277_abnormal_respiratory_mucosa1.00270012
67MP0003698_abnormal_male_reproductive0.99422183
68MP0004147_increased_porphyrin_level0.99036281
69MP0003806_abnormal_nucleotide_metabolis0.95653020
70MP0005391_vision/eye_phenotype0.94821816
71MP0001485_abnormal_pinna_reflex0.92135557
72MP0002160_abnormal_reproductive_system0.91840922
73MP0003315_abnormal_perineum_morphology0.91175773
74MP0002837_dystrophic_cardiac_calcinosis0.89205568
75MP0003283_abnormal_digestive_organ0.87784083
76MP0004142_abnormal_muscle_tone0.87596949
77MP0002085_abnormal_embryonic_tissue0.86411343
78MP0003861_abnormal_nervous_system0.85807250
79MP0001764_abnormal_homeostasis0.85651398
80MP0002697_abnormal_eye_size0.84811686
81MP0002184_abnormal_innervation0.84740758
82MP0009046_muscle_twitch0.83521249
83MP0005389_reproductive_system_phenotype0.82342910
84MP0001119_abnormal_female_reproductive0.81993626
85MP0005423_abnormal_somatic_nervous0.81853919
86MP0002752_abnormal_somatic_nervous0.81535022
87MP0002084_abnormal_developmental_patter0.81410447
88MP0003195_calcinosis0.80812083
89MP0002090_abnormal_vision0.79483264
90MP0005195_abnormal_posterior_eye0.79204222
91MP0000647_abnormal_sebaceous_gland0.77644396
92MP0002111_abnormal_tail_morphology0.75359418
93MP0001697_abnormal_embryo_size0.74371605
94MP0000350_abnormal_cell_proliferation0.74013351
95MP0002272_abnormal_nervous_system0.72477703
96MP0005645_abnormal_hypothalamus_physiol0.71200820
97MP0000026_abnormal_inner_ear0.70929536
98MP0001919_abnormal_reproductive_system0.70300608
99MP0002163_abnormal_gland_morphology0.70056178
100MP0009672_abnormal_birth_weight0.69818727

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.08272274
2Abnormality of the labia minora (HP:0012880)3.73840286
3Abnormal mitochondria in muscle tissue (HP:0008316)3.71889050
4Acute encephalopathy (HP:0006846)3.66730131
5Mitochondrial inheritance (HP:0001427)3.63546585
6Colon cancer (HP:0003003)3.60648632
7Increased hepatocellular lipid droplets (HP:0006565)3.42942248
8Progressive macrocephaly (HP:0004481)3.36405666
9Increased CSF lactate (HP:0002490)3.31249780
10Hepatocellular necrosis (HP:0001404)3.21732263
11Lipid accumulation in hepatocytes (HP:0006561)3.19044453
12Hepatic necrosis (HP:0002605)2.93091669
13Hyperglycinemia (HP:0002154)2.91048317
14Reticulocytopenia (HP:0001896)2.88165898
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.71448996
16Decreased activity of mitochondrial respiratory chain (HP:0008972)2.71448996
17Renal Fanconi syndrome (HP:0001994)2.70745691
18Cerebral edema (HP:0002181)2.70536647
19Meckel diverticulum (HP:0002245)2.70372537
20Aplasia/Hypoplasia of the uvula (HP:0010293)2.66053198
21Abnormal number of erythroid precursors (HP:0012131)2.61072488
22Septo-optic dysplasia (HP:0100842)2.58185439
23Abnormality of cells of the erythroid lineage (HP:0012130)2.58153134
24Abnormality of the ileum (HP:0001549)2.57045322
25Methylmalonic acidemia (HP:0002912)2.56919659
26True hermaphroditism (HP:0010459)2.48310273
27Pancreatic cysts (HP:0001737)2.48147904
28Medial flaring of the eyebrow (HP:0010747)2.44950535
29Pancreatic fibrosis (HP:0100732)2.42047146
30Nephronophthisis (HP:0000090)2.41586677
31Chromosomal breakage induced by crosslinking agents (HP:0003221)2.38517522
32Increased intramyocellular lipid droplets (HP:0012240)2.36040175
33Increased serum lactate (HP:0002151)2.31678119
34Congenital primary aphakia (HP:0007707)2.28519642
353-Methylglutaconic aciduria (HP:0003535)2.28293807
36Lactic acidosis (HP:0003128)2.27894492
37Gait imbalance (HP:0002141)2.26928050
38Macrocytic anemia (HP:0001972)2.26173626
39Molar tooth sign on MRI (HP:0002419)2.24602939
40Abnormality of midbrain morphology (HP:0002418)2.24602939
41Abnormal lung lobation (HP:0002101)2.20809706
42Chromsome breakage (HP:0040012)2.20126339
43Methylmalonic aciduria (HP:0012120)2.18124095
44Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.14624754
45Abnormality of the preputium (HP:0100587)2.14425907
46Nephrogenic diabetes insipidus (HP:0009806)2.11682392
47Ependymoma (HP:0002888)2.08740111
48Abnormality of glycine metabolism (HP:0010895)2.08034255
49Abnormality of serine family amino acid metabolism (HP:0010894)2.08034255
50Respiratory failure (HP:0002878)2.06989685
51Abnormality of chromosome stability (HP:0003220)2.04877561
52Optic disc pallor (HP:0000543)2.04522347
53Pendular nystagmus (HP:0012043)2.03987975
54Triphalangeal thumb (HP:0001199)2.01829441
55Leukodystrophy (HP:0002415)2.01490291
56Hyperglycinuria (HP:0003108)2.00531810
57Medulloblastoma (HP:0002885)1.99397964
58Horseshoe kidney (HP:0000085)1.98549395
59Cerebral hypomyelination (HP:0006808)1.97931391
60Sclerocornea (HP:0000647)1.95941598
61Absent septum pellucidum (HP:0001331)1.94678437
62Vaginal atresia (HP:0000148)1.94538894
63Abnormality of serum amino acid levels (HP:0003112)1.94083558
64Supernumerary spleens (HP:0009799)1.93809995
65Exertional dyspnea (HP:0002875)1.93242029
66Exercise intolerance (HP:0003546)1.92762350
67Genital tract atresia (HP:0001827)1.91032814
68Abnormality of the anterior horn cell (HP:0006802)1.90567366
69Degeneration of anterior horn cells (HP:0002398)1.90567366
70Increased muscle lipid content (HP:0009058)1.88639467
71Hyperinsulinemic hypoglycemia (HP:0000825)1.87356647
72Male pseudohermaphroditism (HP:0000037)1.84892585
73Microvesicular hepatic steatosis (HP:0001414)1.83780729
74Type I transferrin isoform profile (HP:0003642)1.82508520
75Bilateral microphthalmos (HP:0007633)1.81550281
76Lethargy (HP:0001254)1.81538757
77Multiple enchondromatosis (HP:0005701)1.80368155
78Small intestinal stenosis (HP:0012848)1.80305395
79Duodenal stenosis (HP:0100867)1.80305395
80Abnormality of the septum pellucidum (HP:0007375)1.77484058
81Intestinal atresia (HP:0011100)1.77210509
82Sloping forehead (HP:0000340)1.76883912
83Anencephaly (HP:0002323)1.76558826
84Abnormality of the renal medulla (HP:0100957)1.76552432
85Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74912730
86Abnormality of the duodenum (HP:0002246)1.74558407
87Hypoglycemic seizures (HP:0002173)1.73951747
88Absent thumb (HP:0009777)1.72818942
89Hypoplasia of the pons (HP:0012110)1.72700767
90Abnormality of renal resorption (HP:0011038)1.72573307
91Respiratory difficulties (HP:0002880)1.72565979
92Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.72068945
93Increased serum pyruvate (HP:0003542)1.68630309
94Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.67914526
95Abnormal protein glycosylation (HP:0012346)1.66515030
96Abnormal glycosylation (HP:0012345)1.66515030
97Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.66515030
98Abnormal protein N-linked glycosylation (HP:0012347)1.66515030
99Stenosis of the external auditory canal (HP:0000402)1.65906917
100Preaxial hand polydactyly (HP:0001177)1.65612499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.58032140
2CDC73.51257960
3BUB13.47063372
4SRPK13.16966139
5WNK32.99524931
6ZAK2.84303320
7PLK42.42141155
8PBK2.41787874
9STK162.34142154
10VRK12.30205621
11NUAK12.10892456
12DYRK22.07995490
13PLK32.06879713
14TTK2.00129398
15NME11.98907784
16TSSK61.97185730
17MAP3K41.89510956
18TRIM281.83129468
19MAP4K21.81310459
20MAP2K71.61067087
21PLK11.57104360
22TNIK1.50858022
23WEE11.49887600
24NEK11.47942642
25MKNK21.46492840
26MKNK11.43382177
27PNCK1.36654929
28BCKDK1.34420279
29BRSK21.30987511
30MST41.30078846
31ATR1.28229292
32CSNK1G11.27983947
33CSNK1G31.25810349
34TAF11.25237172
35CSNK1G21.19946785
36DYRK31.16935389
37EIF2AK31.13201300
38EIF2AK11.12067768
39BCR1.09729908
40GRK11.09548053
41PASK1.05222717
42TLK11.04965756
43AURKB1.03462885
44BMPR1B1.02568253
45LATS11.00916733
46PLK21.00122973
47CASK0.98607425
48CSNK1A1L0.98021432
49BRSK10.94898786
50CHEK20.94371572
51CDK190.92469430
52AURKA0.86356521
53PINK10.85438656
54INSRR0.83782962
55CCNB10.78598903
56RPS6KA40.77947855
57NME20.77743274
58ATM0.75101508
59CDK30.74234813
60ADRBK20.73015311
61MAPK130.72987022
62PRKCG0.70016861
63PDK20.64347313
64ERBB30.63514577
65CSNK2A20.63403759
66CSNK2A10.63034660
67NEK20.61763565
68STK38L0.61713547
69MINK10.60853072
70ACVR1B0.58902976
71RPS6KA50.58589565
72FRK0.58517281
73CSNK1E0.57547937
74CHEK10.56999384
75MAP3K120.56157599
76KDR0.55469871
77TIE10.51380138
78EPHA40.50942712
79MARK10.50697375
80STK40.46945988
81OXSR10.44585494
82MAPK150.43834127
83CSNK1A10.42738756
84CDK10.41235705
85PRKDC0.40803877
86DAPK10.40402795
87WNK40.39911711
88CDK20.39723380
89CDK70.38006924
90OBSCN0.37888720
91EIF2AK20.37642764
92NTRK20.36201328
93UHMK10.33766550
94IRAK20.33680709
95STK30.32462852
96ERBB40.31591944
97PKN10.29922699
98TESK20.29758034
99CDK140.29195068
100FGFR20.28001295

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.67045004
2Oxidative phosphorylation_Homo sapiens_hsa001903.40410014
3Mismatch repair_Homo sapiens_hsa034303.32986199
4Ribosome_Homo sapiens_hsa030103.20013533
5DNA replication_Homo sapiens_hsa030303.16027488
6RNA polymerase_Homo sapiens_hsa030203.03576261
7Parkinsons disease_Homo sapiens_hsa050123.02463444
8Protein export_Homo sapiens_hsa030602.63822668
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.39387105
10Homologous recombination_Homo sapiens_hsa034402.38640164
11Base excision repair_Homo sapiens_hsa034102.26018827
12Huntingtons disease_Homo sapiens_hsa050162.25437903
13Non-homologous end-joining_Homo sapiens_hsa034502.16693700
14Fanconi anemia pathway_Homo sapiens_hsa034602.12963818
15Spliceosome_Homo sapiens_hsa030402.02471167
16Alzheimers disease_Homo sapiens_hsa050101.92704452
17Nucleotide excision repair_Homo sapiens_hsa034201.86131135
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.85689490
19Basal transcription factors_Homo sapiens_hsa030221.81111132
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77042141
21RNA transport_Homo sapiens_hsa030131.76506984
22Propanoate metabolism_Homo sapiens_hsa006401.69191668
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.67883340
24Pyrimidine metabolism_Homo sapiens_hsa002401.66877124
25One carbon pool by folate_Homo sapiens_hsa006701.66615925
26Fatty acid elongation_Homo sapiens_hsa000621.60131018
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.57810350
28RNA degradation_Homo sapiens_hsa030181.57689688
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.50143449
30Cardiac muscle contraction_Homo sapiens_hsa042601.49602885
31Steroid biosynthesis_Homo sapiens_hsa001001.42616183
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.39306087
33Cell cycle_Homo sapiens_hsa041101.34829915
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.28389808
35Pyruvate metabolism_Homo sapiens_hsa006201.24927610
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.23834817
37Cysteine and methionine metabolism_Homo sapiens_hsa002701.21535507
38Purine metabolism_Homo sapiens_hsa002301.20065346
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.13698023
40Butanoate metabolism_Homo sapiens_hsa006501.13279471
41Selenocompound metabolism_Homo sapiens_hsa004501.02959164
42Folate biosynthesis_Homo sapiens_hsa007901.00258967
43Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.96179768
44Phototransduction_Homo sapiens_hsa047440.92703691
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90545608
46Sulfur relay system_Homo sapiens_hsa041220.88869598
47mRNA surveillance pathway_Homo sapiens_hsa030150.85152173
48Glutathione metabolism_Homo sapiens_hsa004800.83682795
49Maturity onset diabetes of the young_Homo sapiens_hsa049500.82451319
50Vitamin B6 metabolism_Homo sapiens_hsa007500.80158842
51Metabolic pathways_Homo sapiens_hsa011000.78037435
52Nicotine addiction_Homo sapiens_hsa050330.77623475
532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77109470
54Oocyte meiosis_Homo sapiens_hsa041140.74752367
55beta-Alanine metabolism_Homo sapiens_hsa004100.69799457
56Carbon metabolism_Homo sapiens_hsa012000.69335915
57Peroxisome_Homo sapiens_hsa041460.67562424
58Basal cell carcinoma_Homo sapiens_hsa052170.65352087
59Biosynthesis of amino acids_Homo sapiens_hsa012300.65227282
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64873315
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61310539
62Fatty acid metabolism_Homo sapiens_hsa012120.60810761
63Regulation of autophagy_Homo sapiens_hsa041400.57113575
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55641071
65Hedgehog signaling pathway_Homo sapiens_hsa043400.55296150
66Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51702547
67Vitamin digestion and absorption_Homo sapiens_hsa049770.50629576
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.50163811
69Tryptophan metabolism_Homo sapiens_hsa003800.50042066
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47300298
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47298216
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.44769240
73p53 signaling pathway_Homo sapiens_hsa041150.43931657
74Fatty acid degradation_Homo sapiens_hsa000710.42847921
75Arginine and proline metabolism_Homo sapiens_hsa003300.42368195
76Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41966254
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41316044
78Collecting duct acid secretion_Homo sapiens_hsa049660.39728738
79Chemical carcinogenesis_Homo sapiens_hsa052040.38831310
80Retinol metabolism_Homo sapiens_hsa008300.38437642
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37026686
82Taste transduction_Homo sapiens_hsa047420.36229458
83Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.35693220
84Primary bile acid biosynthesis_Homo sapiens_hsa001200.35648855
85Nitrogen metabolism_Homo sapiens_hsa009100.34620740
86Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34191902
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33984028
88Linoleic acid metabolism_Homo sapiens_hsa005910.31669824
89Drug metabolism - other enzymes_Homo sapiens_hsa009830.31013359
90Wnt signaling pathway_Homo sapiens_hsa043100.30782024
91Caffeine metabolism_Homo sapiens_hsa002320.29971133
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28942182
93Alcoholism_Homo sapiens_hsa050340.24260971
94Tyrosine metabolism_Homo sapiens_hsa003500.22987072
95N-Glycan biosynthesis_Homo sapiens_hsa005100.21847065
96Hippo signaling pathway_Homo sapiens_hsa043900.21593438
97Ether lipid metabolism_Homo sapiens_hsa005650.21108648
98Systemic lupus erythematosus_Homo sapiens_hsa053220.19570371
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.19231430
100Olfactory transduction_Homo sapiens_hsa047400.19184100

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »