ZDHHC8P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)4.87054215
2behavioral response to nicotine (GO:0035095)3.97944632
3regulation of male gonad development (GO:2000018)3.66281219
4positive regulation of male gonad development (GO:2000020)3.50218128
5presynaptic membrane assembly (GO:0097105)3.49455461
6dendritic spine morphogenesis (GO:0060997)3.34437843
7presynaptic membrane organization (GO:0097090)3.21162963
8pyrimidine nucleobase catabolic process (GO:0006208)3.17247428
9neuron cell-cell adhesion (GO:0007158)3.10933102
10seminiferous tubule development (GO:0072520)3.08631540
11L-fucose catabolic process (GO:0042355)3.07221837
12fucose catabolic process (GO:0019317)3.07221837
13L-fucose metabolic process (GO:0042354)3.07221837
14protein polyglutamylation (GO:0018095)3.01340194
15water-soluble vitamin biosynthetic process (GO:0042364)2.96681191
16limb bud formation (GO:0060174)2.93156963
17postsynaptic membrane organization (GO:0001941)2.92570385
18membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.91153500
19negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.87776902
20sex determination (GO:0007530)2.87557841
21auditory behavior (GO:0031223)2.85807106
22parturition (GO:0007567)2.85308922
23platelet dense granule organization (GO:0060155)2.83740125
24epithelial cilium movement (GO:0003351)2.83473959
25gamma-aminobutyric acid transport (GO:0015812)2.83303401
26protein localization to cilium (GO:0061512)2.82950695
27axoneme assembly (GO:0035082)2.82359497
28neuronal action potential (GO:0019228)2.78331361
29vocalization behavior (GO:0071625)2.77804507
30cardiac right ventricle morphogenesis (GO:0003215)2.77330148
31ionotropic glutamate receptor signaling pathway (GO:0035235)2.75638689
32G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.75538739
33glycerophospholipid catabolic process (GO:0046475)2.74769018
34negative regulation of synaptic transmission, GABAergic (GO:0032229)2.74556985
35axonal fasciculation (GO:0007413)2.73248279
36nucleobase catabolic process (GO:0046113)2.72855583
37nonmotile primary cilium assembly (GO:0035058)2.71631443
38glutamate receptor signaling pathway (GO:0007215)2.71006899
39somite development (GO:0061053)2.70094368
40regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68021184
41cornea development in camera-type eye (GO:0061303)2.67786909
42positive regulation of meiosis (GO:0045836)2.66779471
43regulation of non-canonical Wnt signaling pathway (GO:2000050)2.66042904
44serotonin metabolic process (GO:0042428)2.63429848
45DNA strand renaturation (GO:0000733)2.62910225
46regulation of cilium movement (GO:0003352)2.62171724
47negative regulation of cytosolic calcium ion concentration (GO:0051481)2.61726784
48inositol phosphate catabolic process (GO:0071545)2.60625067
49C4-dicarboxylate transport (GO:0015740)2.60016093
50primary amino compound metabolic process (GO:1901160)2.59133880
51cellular ketone body metabolic process (GO:0046950)2.58967713
52startle response (GO:0001964)2.57818733
53regulation of action potential (GO:0098900)2.57681609
54intraciliary transport (GO:0042073)2.56863944
55membrane depolarization during action potential (GO:0086010)2.53925936
56synaptic transmission, glutamatergic (GO:0035249)2.53786085
57regulation of female gonad development (GO:2000194)2.53501687
58behavioral response to ethanol (GO:0048149)2.53221135
59cilium assembly (GO:0042384)2.52943636
60cilium organization (GO:0044782)2.52243669
61retinal ganglion cell axon guidance (GO:0031290)2.52147258
62adaptation of signaling pathway (GO:0023058)2.52077403
63detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.51722008
64positive regulation of meiotic cell cycle (GO:0051446)2.48703783
65positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.47076545
66regulation of mesenchymal cell apoptotic process (GO:2001053)2.43559745
67cell proliferation in forebrain (GO:0021846)2.43013121
68kidney morphogenesis (GO:0060993)2.41852629
69photoreceptor cell maintenance (GO:0045494)2.41645460
70cilium morphogenesis (GO:0060271)2.39796054
71mechanosensory behavior (GO:0007638)2.39075026
72protein localization to synapse (GO:0035418)2.38061612
73epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.37234770
74indole-containing compound catabolic process (GO:0042436)2.35216726
75indolalkylamine catabolic process (GO:0046218)2.35216726
76tryptophan catabolic process (GO:0006569)2.35216726
77regulation of short-term neuronal synaptic plasticity (GO:0048172)2.35018958
78limb development (GO:0060173)2.34090802
79appendage development (GO:0048736)2.34090802
80negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.33715486
81sperm motility (GO:0030317)2.33274668
82neuronal action potential propagation (GO:0019227)2.33124452
83synapse assembly (GO:0007416)2.33091796
84epithelial cell fate commitment (GO:0072148)2.33090798
85regulation of glomerulus development (GO:0090192)2.32830851
86hindbrain development (GO:0030902)2.32819383
87positive regulation of oligodendrocyte differentiation (GO:0048714)2.32441816
88piRNA metabolic process (GO:0034587)2.32368126
89glycosphingolipid biosynthetic process (GO:0006688)2.32221318
90DNA deamination (GO:0045006)2.32149456
91regulation of microtubule-based movement (GO:0060632)2.31298415
92spinal cord motor neuron differentiation (GO:0021522)2.30350204
93indolalkylamine metabolic process (GO:0006586)2.30249629
94indole-containing compound metabolic process (GO:0042430)2.30193924
95central nervous system projection neuron axonogenesis (GO:0021952)2.29143102
96ketone body metabolic process (GO:1902224)2.28919554
97regulation of timing of cell differentiation (GO:0048505)2.28875667
98central nervous system neuron axonogenesis (GO:0021955)2.28453914
99male sex determination (GO:0030238)2.27966602
100brain morphogenesis (GO:0048854)2.27743353

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.57172972
2GBX2_23144817_ChIP-Seq_PC3_Human3.19339102
3ZNF274_21170338_ChIP-Seq_K562_Hela2.89013321
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.64846766
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.59151291
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.46437521
7VDR_22108803_ChIP-Seq_LS180_Human2.46221726
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.37750191
9IGF1R_20145208_ChIP-Seq_DFB_Human2.16564663
10CTBP1_25329375_ChIP-Seq_LNCAP_Human2.14273962
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.11068006
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.02905821
13TAF15_26573619_Chip-Seq_HEK293_Human1.99860463
14CBX2_27304074_Chip-Seq_ESCs_Mouse1.98629109
15P300_19829295_ChIP-Seq_ESCs_Human1.91157220
16RNF2_27304074_Chip-Seq_NSC_Mouse1.88578561
17REST_21632747_ChIP-Seq_MESCs_Mouse1.87991431
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.84199488
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.83972565
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.81948229
21FUS_26573619_Chip-Seq_HEK293_Human1.81146258
22BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79915095
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.75240343
24EWS_26573619_Chip-Seq_HEK293_Human1.75149794
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.73741150
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.70608958
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.70034468
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.68791395
29TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68699023
30POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.68699023
31JARID2_20064375_ChIP-Seq_MESCs_Mouse1.68484413
32EED_16625203_ChIP-ChIP_MESCs_Mouse1.66761658
33AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.66478375
34ER_23166858_ChIP-Seq_MCF-7_Human1.62433522
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60349992
36* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.58912993
37SMAD4_21799915_ChIP-Seq_A2780_Human1.57554855
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.56898561
39* SMAD3_21741376_ChIP-Seq_EPCs_Human1.55541291
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.54568282
41UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.53990572
42AR_25329375_ChIP-Seq_VCAP_Human1.53376843
43SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.52162513
44BCAT_22108803_ChIP-Seq_LS180_Human1.49910691
45TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48489476
46CBP_20019798_ChIP-Seq_JUKART_Human1.46147662
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46147662
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45799960
49SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.43306056
50REST_18959480_ChIP-ChIP_MESCs_Mouse1.42589596
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.41792524
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.41595556
53STAT3_23295773_ChIP-Seq_U87_Human1.41422246
54TCF4_23295773_ChIP-Seq_U87_Human1.38465184
55EZH2_27294783_Chip-Seq_ESCs_Mouse1.36108994
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35811472
57SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32917509
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30173260
59JARID2_20075857_ChIP-Seq_MESCs_Mouse1.29962383
60RNF2_27304074_Chip-Seq_ESCs_Mouse1.29899416
61MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28813784
62SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.28707384
63NR3C1_21868756_ChIP-Seq_MCF10A_Human1.28487205
64SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28237259
65TP53_22573176_ChIP-Seq_HFKS_Human1.26831483
66SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.25207623
67* RUNX2_22187159_ChIP-Seq_PCA_Human1.24612774
68EZH2_18974828_ChIP-Seq_MESCs_Mouse1.24361708
69RNF2_18974828_ChIP-Seq_MESCs_Mouse1.24361708
70SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.24288812
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22891485
72NANOG_18555785_Chip-Seq_ESCs_Mouse1.22799558
73PCGF2_27294783_Chip-Seq_NPCs_Mouse1.22748399
74EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.22443907
75* TCF4_22108803_ChIP-Seq_LS180_Human1.22388466
76TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20132227
77* SMAD4_21741376_ChIP-Seq_EPCs_Human1.19663635
78OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19039881
79* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17606498
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15829319
81DROSHA_22980978_ChIP-Seq_HELA_Human1.15650686
82MTF2_20144788_ChIP-Seq_MESCs_Mouse1.14401695
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12210934
84KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11153937
85NANOG_19829295_ChIP-Seq_ESCs_Human1.10010334
86SOX2_19829295_ChIP-Seq_ESCs_Human1.10010334
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.08383684
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07734074
89POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07648689
90EZH2_27294783_Chip-Seq_NPCs_Mouse1.07406513
91KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.06548790
92FLI1_21867929_ChIP-Seq_TH2_Mouse1.06233501
93SOX2_21211035_ChIP-Seq_LN229_Gbm1.05447012
94FOXA1_25329375_ChIP-Seq_VCAP_Human1.04728276
95FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04728276
96PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04481173
97AR_21572438_ChIP-Seq_LNCaP_Human1.04320871
98P53_22387025_ChIP-Seq_ESCs_Mouse1.04210197
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.03915161
100EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02614900

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001968_abnormal_touch/_nociception2.74436085
2MP0002102_abnormal_ear_morphology2.62795746
3MP0003880_abnormal_central_pattern2.55788267
4MP0003122_maternal_imprinting2.46197668
5MP0008877_abnormal_DNA_methylation2.44798244
6MP0002736_abnormal_nociception_after2.40381078
7MP0003787_abnormal_imprinting2.37825486
8MP0009745_abnormal_behavioral_response2.23295661
9MP0002272_abnormal_nervous_system2.10630938
10MP0004885_abnormal_endolymph2.05576714
11MP0001486_abnormal_startle_reflex2.04326754
12MP0009046_muscle_twitch2.02934840
13MP0008995_early_reproductive_senescence1.99976475
14MP0005646_abnormal_pituitary_gland1.92141981
15MP0003635_abnormal_synaptic_transmissio1.91883562
16MP0003195_calcinosis1.88665412
17MP0004270_analgesia1.88181055
18MP0005551_abnormal_eye_electrophysiolog1.88117505
19MP0002735_abnormal_chemical_nociception1.87069362
20MP0003121_genomic_imprinting1.86203523
21MP0003283_abnormal_digestive_organ1.86065842
22MP0006292_abnormal_olfactory_placode1.83467905
23MP0006072_abnormal_retinal_apoptosis1.81080000
24MP0002837_dystrophic_cardiac_calcinosis1.78576248
25MP0002572_abnormal_emotion/affect_behav1.76249332
26MP0001984_abnormal_olfaction1.74579944
27MP0004859_abnormal_synaptic_plasticity1.72467434
28MP0002064_seizures1.68858502
29MP0000778_abnormal_nervous_system1.68837354
30MP0002063_abnormal_learning/memory/cond1.66097465
31MP0002734_abnormal_mechanical_nocicepti1.63205687
32MP0004133_heterotaxia1.60928482
33MP0001501_abnormal_sleep_pattern1.60609589
34MP0000631_abnormal_neuroendocrine_gland1.58529969
35MP0002557_abnormal_social/conspecific_i1.57888685
36MP0001485_abnormal_pinna_reflex1.53593795
37MP0006276_abnormal_autonomic_nervous1.52656685
38MP0001970_abnormal_pain_threshold1.52242421
39MP0010386_abnormal_urinary_bladder1.48013856
40MP0002733_abnormal_thermal_nociception1.46242266
41MP0002638_abnormal_pupillary_reflex1.43377801
42MP0004142_abnormal_muscle_tone1.41796412
43MP0000566_synostosis1.41565887
44MP0002909_abnormal_adrenal_gland1.36492561
45MP0002822_catalepsy1.36198667
46MP0005253_abnormal_eye_physiology1.34316926
47MP0005423_abnormal_somatic_nervous1.32244296
48MP0000516_abnormal_urinary_system1.30002888
49MP0005367_renal/urinary_system_phenotyp1.30002888
50MP0002184_abnormal_innervation1.27890260
51MP0001529_abnormal_vocalization1.27037600
52MP0008872_abnormal_physiological_respon1.26705606
53MP0002067_abnormal_sensory_capabilities1.23856738
54MP0002751_abnormal_autonomic_nervous1.23320872
55MP0002876_abnormal_thyroid_physiology1.22717650
56MP0004742_abnormal_vestibular_system1.22403609
57MP0005377_hearing/vestibular/ear_phenot1.21995648
58MP0003878_abnormal_ear_physiology1.21995648
59MP0003119_abnormal_digestive_system1.21641900
60MP0002938_white_spotting1.18342565
61MP0005645_abnormal_hypothalamus_physiol1.17702833
62MP0001986_abnormal_taste_sensitivity1.17627252
63MP0002234_abnormal_pharynx_morphology1.15029879
64MP0003011_delayed_dark_adaptation1.11992247
65MP0004924_abnormal_behavior1.11699470
66MP0005386_behavior/neurological_phenoty1.11699470
67MP0002653_abnormal_ependyma_morphology1.09802654
68MP0000538_abnormal_urinary_bladder1.08111606
69MP0001502_abnormal_circadian_rhythm1.06322512
70MP0008789_abnormal_olfactory_epithelium1.06005386
71MP0000955_abnormal_spinal_cord1.05857747
72MP0000639_abnormal_adrenal_gland1.05832417
73MP0008875_abnormal_xenobiotic_pharmacok1.04667216
74MP0001440_abnormal_grooming_behavior1.04040524
75MP0005389_reproductive_system_phenotype1.03110769
76MP0002882_abnormal_neuron_morphology1.00830334
77MP0001905_abnormal_dopamine_level1.00147771
78MP0004145_abnormal_muscle_electrophysio0.98321880
79MP0005499_abnormal_olfactory_system0.97996632
80MP0005394_taste/olfaction_phenotype0.97996632
81MP0000569_abnormal_digit_pigmentation0.97364693
82MP0005379_endocrine/exocrine_gland_phen0.97034392
83MP0003137_abnormal_impulse_conducting0.96502952
84MP0002229_neurodegeneration0.95904275
85MP0002752_abnormal_somatic_nervous0.95537623
86MP0000427_abnormal_hair_cycle0.93709375
87MP0005410_abnormal_fertilization0.93620294
88MP0003937_abnormal_limbs/digits/tail_de0.92579521
89MP0002928_abnormal_bile_duct0.92452392
90MP0001944_abnormal_pancreas_morphology0.92403371
91MP0001919_abnormal_reproductive_system0.91224668
92MP0000026_abnormal_inner_ear0.89137216
93MP0004147_increased_porphyrin_level0.88749813
94MP0003646_muscle_fatigue0.87972833
95MP0003698_abnormal_male_reproductive0.87692072
96MP0001963_abnormal_hearing_physiology0.87405331
97MP0003938_abnormal_ear_development0.86151524
98MP0003879_abnormal_hair_cell0.86103274
99MP0009780_abnormal_chondrocyte_physiolo0.85808808
100MP0005195_abnormal_posterior_eye0.82108137

Predicted human phenotypes

RankGene SetZ-score
1True hermaphroditism (HP:0010459)4.42736408
2Pancreatic cysts (HP:0001737)3.60595055
3Medial flaring of the eyebrow (HP:0010747)3.28965181
4Pancreatic fibrosis (HP:0100732)3.26222435
5Gonadal dysgenesis (HP:0000133)3.22723937
6Abnormality of midbrain morphology (HP:0002418)3.21541628
7Molar tooth sign on MRI (HP:0002419)3.21541628
8Nephronophthisis (HP:0000090)3.14015984
9Hyperventilation (HP:0002883)3.10851422
10Male pseudohermaphroditism (HP:0000037)3.06072189
11Gait imbalance (HP:0002141)2.93012916
12Abnormality of the labia minora (HP:0012880)2.91925604
13Sex reversal (HP:0012245)2.83880404
14Abnormal sex determination (HP:0012244)2.83880404
15Focal seizures (HP:0007359)2.83501315
16Focal motor seizures (HP:0011153)2.82777171
17Abnormality of the renal medulla (HP:0100957)2.73938869
18Abnormality of the renal cortex (HP:0011035)2.73294497
19Congenital primary aphakia (HP:0007707)2.67248146
20Chronic hepatic failure (HP:0100626)2.63370300
21Genital tract atresia (HP:0001827)2.59407312
22Cystic liver disease (HP:0006706)2.59181278
23Progressive cerebellar ataxia (HP:0002073)2.58139909
24Nephrogenic diabetes insipidus (HP:0009806)2.51555650
25Testicular neoplasm (HP:0010788)2.51086771
26Vaginal atresia (HP:0000148)2.48588783
27Aplasia/hypoplasia of the uterus (HP:0008684)2.43000730
28Intestinal atresia (HP:0011100)2.38075903
29Congenital stationary night blindness (HP:0007642)2.35897271
30Gaze-evoked nystagmus (HP:0000640)2.34570254
31Hemiparesis (HP:0001269)2.34340461
32Shawl scrotum (HP:0000049)2.28897369
33Febrile seizures (HP:0002373)2.25778708
34Hypoplasia of the uterus (HP:0000013)2.25058886
35Mesangial abnormality (HP:0001966)2.24828736
36Abnormality of macular pigmentation (HP:0008002)2.24782127
37Type II lissencephaly (HP:0007260)2.23442337
38Abolished electroretinogram (ERG) (HP:0000550)2.19466880
39Tubular atrophy (HP:0000092)2.17216994
40Renal cortical cysts (HP:0000803)2.16552218
41Broad-based gait (HP:0002136)2.15021674
42Aplasia/Hypoplasia of the tibia (HP:0005772)2.12139037
43Large for gestational age (HP:0001520)2.12051891
44Postaxial hand polydactyly (HP:0001162)2.08831393
45Congenital hepatic fibrosis (HP:0002612)2.08714336
46Oligodactyly (hands) (HP:0001180)2.07483173
47Genetic anticipation (HP:0003743)2.06009602
48Pendular nystagmus (HP:0012043)2.05888903
49Volvulus (HP:0002580)2.05459328
50Abnormal rod and cone electroretinograms (HP:0008323)2.05185486
51Limb dystonia (HP:0002451)2.04125880
52Gastrointestinal atresia (HP:0002589)2.03122460
53Degeneration of the lateral corticospinal tracts (HP:0002314)2.02810132
54Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.02810132
55Sclerocornea (HP:0000647)2.01960673
56Optic nerve hypoplasia (HP:0000609)1.98987358
57Epileptic encephalopathy (HP:0200134)1.94109029
58Postaxial foot polydactyly (HP:0001830)1.93784023
59Attenuation of retinal blood vessels (HP:0007843)1.93084067
60Inability to walk (HP:0002540)1.93012730
61Dialeptic seizures (HP:0011146)1.90575635
62Preaxial hand polydactyly (HP:0001177)1.90279868
63Abnormal drinking behavior (HP:0030082)1.90255294
64Polydipsia (HP:0001959)1.90255294
65Lissencephaly (HP:0001339)1.90189942
66Myokymia (HP:0002411)1.88883495
67Aplasia/Hypoplasia of the tongue (HP:0010295)1.87484837
68Adrenal hypoplasia (HP:0000835)1.87135637
69Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.87119631
70Poor coordination (HP:0002370)1.86016013
71Anencephaly (HP:0002323)1.85270431
72Polyphagia (HP:0002591)1.84833573
73Hypothermia (HP:0002045)1.84517982
74Atonic seizures (HP:0010819)1.84071079
753-Methylglutaconic aciduria (HP:0003535)1.82439549
76Increased corneal curvature (HP:0100692)1.80666845
77Keratoconus (HP:0000563)1.80666845
78Progressive inability to walk (HP:0002505)1.79997672
79Short tibia (HP:0005736)1.79918836
80Specific learning disability (HP:0001328)1.78800501
81Neoplasm of the adrenal cortex (HP:0100641)1.77610766
82Severe visual impairment (HP:0001141)1.76705028
83Abnormal biliary tract physiology (HP:0012439)1.75784010
84Bile duct proliferation (HP:0001408)1.75784010
85Hypoplastic left heart (HP:0004383)1.75463927
86Anophthalmia (HP:0000528)1.74425572
87Bilateral microphthalmos (HP:0007633)1.74375072
88Retinal dysplasia (HP:0007973)1.73732558
89Pachygyria (HP:0001302)1.73693399
90Arthropathy (HP:0003040)1.73422712
91Absent speech (HP:0001344)1.73068693
92Esophageal atresia (HP:0002032)1.73059122
93Congenital malformation of the right heart (HP:0011723)1.71663408
94Double outlet right ventricle (HP:0001719)1.71663408
95Small hand (HP:0200055)1.71372505
96Abnormality of the corticospinal tract (HP:0002492)1.70453236
97Severe muscular hypotonia (HP:0006829)1.68966225
98Narrow forehead (HP:0000341)1.67258139
99Methylmalonic acidemia (HP:0002912)1.66940353
100Short foot (HP:0001773)1.64302813

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.20755853
2MARK12.73133827
3WNK32.68117934
4CASK2.61501371
5MAP4K22.48341324
6TNIK2.46677063
7ADRBK22.37606411
8PINK12.29026699
9BMPR1B2.26645668
10MAPK132.26487558
11EPHA42.17603194
12MAP3K42.16900464
13NUAK12.06473535
14NTRK32.01639287
15FGFR21.93353796
16FER1.89976579
17GRK11.85653558
18OXSR11.72030829
19DAPK21.67012805
20TRIM281.65740460
21PLK21.62748948
22PNCK1.54782325
23ACVR1B1.54647810
24MAP2K71.50726248
25INSRR1.38962253
26DYRK21.36581838
27PRKCG1.35716681
28PAK31.34876270
29ZAK1.33623850
30PHKG11.30638766
31PHKG21.30638766
32WNK41.30305908
33PRKCE1.27478254
34CSNK1G11.24983051
35PRKD31.24712920
36MKNK21.23342046
37NTRK21.23003535
38NLK1.12174586
39CSNK1G21.11576164
40FES1.04076042
41STK391.01897739
42MINK10.97174707
43CSNK1G30.96061149
44STK38L0.90703178
45ADRBK10.90214522
46CAMK10.87740928
47CDK190.87706037
48SGK20.86185445
49SGK4940.85495965
50SGK2230.85495965
51GRK50.82551057
52PLK40.82449305
53BCR0.81319437
54TAOK30.80007252
55UHMK10.77581857
56CAMKK20.73546908
57MST40.72333776
58CSNK1A1L0.71385598
59STK110.70130259
60CAMK1G0.69601727
61GRK70.68946661
62CAMK2A0.65771523
63EIF2AK30.65435258
64TLK10.65002434
65DYRK1A0.61800053
66MAPKAPK50.60554804
67PRKACA0.59980073
68PLK30.59898566
69CSNK1A10.58408860
70MAP2K60.57609240
71ERBB30.57539016
72PKN10.56058142
73AKT30.53063191
74PRKCZ0.52392686
75BRSK20.52211384
76PAK60.52122415
77MKNK10.51351350
78CAMK2B0.50600053
79TIE10.50156185
80CDK50.48717456
81SGK10.48080535
82TGFBR10.47244508
83PRKG10.45964272
84MAP2K40.42981747
85PRKCI0.41026936
86TNK20.39946509
87CSNK1D0.38369716
88PRKAA20.37244564
89PRKCA0.36964585
90EIF2AK20.36168665
91NME10.36115718
92MAP3K120.35678941
93MAPK150.35334203
94DAPK10.35130484
95EPHB20.34466158
96VRK10.34167589
97ROCK10.33984945
98CAMK1D0.32667383
99ERBB20.32565692
100PRKAA10.32396850

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.41026495
2Maturity onset diabetes of the young_Homo sapiens_hsa049502.64860047
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.40165611
4Phototransduction_Homo sapiens_hsa047442.29043883
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.27276357
6Protein export_Homo sapiens_hsa030602.10553484
7Butanoate metabolism_Homo sapiens_hsa006502.02776864
8Insulin secretion_Homo sapiens_hsa049111.97965396
9Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.93138033
10GABAergic synapse_Homo sapiens_hsa047271.89461174
11Linoleic acid metabolism_Homo sapiens_hsa005911.77975019
12Oxidative phosphorylation_Homo sapiens_hsa001901.77703753
13Circadian entrainment_Homo sapiens_hsa047131.77237370
14Taste transduction_Homo sapiens_hsa047421.73698592
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.68819794
16Morphine addiction_Homo sapiens_hsa050321.67575075
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67405129
18Glutamatergic synapse_Homo sapiens_hsa047241.65347844
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.62933183
20Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.61618957
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.58549561
22Olfactory transduction_Homo sapiens_hsa047401.49982492
23Ether lipid metabolism_Homo sapiens_hsa005651.49638446
24Selenocompound metabolism_Homo sapiens_hsa004501.48807186
25Synaptic vesicle cycle_Homo sapiens_hsa047211.43660323
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.43494262
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.38223845
28Amphetamine addiction_Homo sapiens_hsa050311.36822991
29Tryptophan metabolism_Homo sapiens_hsa003801.35812645
30Propanoate metabolism_Homo sapiens_hsa006401.31777648
31Dopaminergic synapse_Homo sapiens_hsa047281.31729910
32Parkinsons disease_Homo sapiens_hsa050121.31270107
33Hedgehog signaling pathway_Homo sapiens_hsa043401.29836716
34Salivary secretion_Homo sapiens_hsa049701.28473077
35Steroid biosynthesis_Homo sapiens_hsa001001.26120376
36Cocaine addiction_Homo sapiens_hsa050301.25610475
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23878346
38Caffeine metabolism_Homo sapiens_hsa002321.21694438
39Cardiac muscle contraction_Homo sapiens_hsa042601.20814456
40Serotonergic synapse_Homo sapiens_hsa047261.17119510
41ABC transporters_Homo sapiens_hsa020101.15627898
42Nitrogen metabolism_Homo sapiens_hsa009101.14242726
43Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.12969448
44Basal transcription factors_Homo sapiens_hsa030221.11605171
45Gastric acid secretion_Homo sapiens_hsa049711.05007711
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02992043
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.99806962
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.97981797
49Peroxisome_Homo sapiens_hsa041460.95493371
50Chemical carcinogenesis_Homo sapiens_hsa052040.94647499
51Collecting duct acid secretion_Homo sapiens_hsa049660.94014713
52Ovarian steroidogenesis_Homo sapiens_hsa049130.92699284
53Alzheimers disease_Homo sapiens_hsa050100.92364233
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.91721989
55Homologous recombination_Homo sapiens_hsa034400.91455607
56Calcium signaling pathway_Homo sapiens_hsa040200.90161015
57Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88608670
58Long-term depression_Homo sapiens_hsa047300.88223643
59Vitamin B6 metabolism_Homo sapiens_hsa007500.87929141
60Regulation of autophagy_Homo sapiens_hsa041400.84995926
61Retinol metabolism_Homo sapiens_hsa008300.84670498
62Cholinergic synapse_Homo sapiens_hsa047250.83137950
63Huntingtons disease_Homo sapiens_hsa050160.83029843
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.78905187
65beta-Alanine metabolism_Homo sapiens_hsa004100.78781416
66Fanconi anemia pathway_Homo sapiens_hsa034600.78748942
67cAMP signaling pathway_Homo sapiens_hsa040240.77292492
68Primary bile acid biosynthesis_Homo sapiens_hsa001200.77058776
69Renin secretion_Homo sapiens_hsa049240.76208711
70Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73644618
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72726887
72Axon guidance_Homo sapiens_hsa043600.71734830
73Basal cell carcinoma_Homo sapiens_hsa052170.69597157
74Fatty acid elongation_Homo sapiens_hsa000620.68092045
75RNA degradation_Homo sapiens_hsa030180.66808639
76RNA polymerase_Homo sapiens_hsa030200.65595358
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64623189
78Oxytocin signaling pathway_Homo sapiens_hsa049210.64512777
79Mineral absorption_Homo sapiens_hsa049780.63205118
80Histidine metabolism_Homo sapiens_hsa003400.61567587
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.59717332
82Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.59302656
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59003256
84Metabolic pathways_Homo sapiens_hsa011000.52740159
85Circadian rhythm_Homo sapiens_hsa047100.51916795
86Dorso-ventral axis formation_Homo sapiens_hsa043200.51547686
87Non-homologous end-joining_Homo sapiens_hsa034500.50990667
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.49503050
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.47237676
90Arginine and proline metabolism_Homo sapiens_hsa003300.46673196
91Arachidonic acid metabolism_Homo sapiens_hsa005900.45920841
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.45196789
93Glycerolipid metabolism_Homo sapiens_hsa005610.43234657
94Pancreatic secretion_Homo sapiens_hsa049720.42604064
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.42050879
96Thyroid hormone synthesis_Homo sapiens_hsa049180.40460222
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.39357258
98Lysine degradation_Homo sapiens_hsa003100.37298943
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36781600
100Type II diabetes mellitus_Homo sapiens_hsa049300.36609824

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »