ZDHHC11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.96247947
2motile cilium assembly (GO:0044458)9.88027348
3epithelial cilium movement (GO:0003351)9.74269635
4axonemal dynein complex assembly (GO:0070286)9.65662007
5spermatid development (GO:0007286)9.29633593
6cilium movement (GO:0003341)7.84861743
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.75701683
8regulation of cilium movement (GO:0003352)7.66206775
9single fertilization (GO:0007338)7.53340224
10piRNA metabolic process (GO:0034587)7.01587110
11sperm capacitation (GO:0048240)6.78804160
12male meiosis (GO:0007140)6.78480080
13synaptonemal complex organization (GO:0070193)6.66301086
14synaptonemal complex assembly (GO:0007130)6.51330851
15negative regulation of inclusion body assembly (GO:0090084)6.48328430
16microtubule depolymerization (GO:0007019)6.39780252
17spermatogenesis (GO:0007283)6.35658576
18male gamete generation (GO:0048232)6.33258598
19fertilization (GO:0009566)6.19141248
20organic cation transport (GO:0015695)6.15564954
21gamete generation (GO:0007276)5.82058798
22calcium ion-dependent exocytosis (GO:0017156)5.64107465
23spermatid nucleus differentiation (GO:0007289)5.47232834
24regulation of inclusion body assembly (GO:0090083)5.40403907
25cellular process involved in reproduction in multicellular organism (GO:0022412)5.22594833
26germ cell development (GO:0007281)5.22022872
27cell recognition (GO:0008037)5.12026654
28ventricular system development (GO:0021591)5.05791836
29polyamine biosynthetic process (GO:0006596)4.76971359
30glycerol ether metabolic process (GO:0006662)4.68439242
31chromosome condensation (GO:0030261)4.58979261
32multicellular organismal reproductive process (GO:0048609)4.58536589
33DNA methylation involved in gamete generation (GO:0043046)4.53988929
34regulation of microtubule-based movement (GO:0060632)4.48338261
35chromosome organization involved in meiosis (GO:0070192)4.40886251
36microtubule severing (GO:0051013)4.38901174
37male meiosis I (GO:0007141)4.38537405
38ether metabolic process (GO:0018904)4.32490838
39seminiferous tubule development (GO:0072520)4.28031259
40DNA packaging (GO:0006323)4.27255366
41meiotic nuclear division (GO:0007126)4.00179741
42chaperone-mediated protein complex assembly (GO:0051131)3.99977386
43sexual reproduction (GO:0019953)3.82620167
44single strand break repair (GO:0000012)3.80696802
45left/right pattern formation (GO:0060972)3.75605105
46behavioral response to nicotine (GO:0035095)3.70130716
47multicellular organismal development (GO:0007275)3.69409931
48microtubule bundle formation (GO:0001578)3.54884494
49establishment of monopolar cell polarity (GO:0061162)3.45246333
50establishment or maintenance of monopolar cell polarity (GO:0061339)3.45246333
51cell migration in hindbrain (GO:0021535)3.43674936
52meiosis I (GO:0007127)3.42167577
53microtubule polymerization or depolymerization (GO:0031109)3.31488262
54protein localization to cilium (GO:0061512)3.29622780
55intraciliary transport (GO:0042073)3.29193726
56protein K11-linked deubiquitination (GO:0035871)3.28485375
57cornea development in camera-type eye (GO:0061303)3.25078702
58regulation of spindle checkpoint (GO:0090231)3.24768092
59genitalia morphogenesis (GO:0035112)3.24521958
60meiotic cell cycle (GO:0051321)3.20970376
61establishment of mitochondrion localization (GO:0051654)3.18483728
62polyol catabolic process (GO:0046174)3.17997487
63centriole assembly (GO:0098534)3.17933041
64melanin biosynthetic process (GO:0042438)3.15029918
65amine biosynthetic process (GO:0009309)3.12709789
66cellular biogenic amine biosynthetic process (GO:0042401)3.12709789
67alditol metabolic process (GO:0019400)3.11922590
68carnitine transport (GO:0015879)3.10936916
69amino-acid betaine transport (GO:0015838)3.10936916
70sequestering of actin monomers (GO:0042989)3.09568757
71left/right axis specification (GO:0070986)3.08113531
72monoubiquitinated protein deubiquitination (GO:0035520)3.04955232
73cilium morphogenesis (GO:0060271)2.98689618
74meiotic chromosome segregation (GO:0045132)2.97186953
75peptidyl-threonine dephosphorylation (GO:0035970)2.96663400
76carnitine transmembrane transport (GO:1902603)2.94437236
77cranial nerve morphogenesis (GO:0021602)2.88759338
78nucleus organization (GO:0006997)2.88368895
79embryonic body morphogenesis (GO:0010172)2.88079240
80establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.88039000
81mitochondrion transport along microtubule (GO:0047497)2.88039000
82regulation of synapse structural plasticity (GO:0051823)2.87169735
83protein polyglutamylation (GO:0018095)2.84283001
84melanin metabolic process (GO:0006582)2.83253292
85positive regulation of macrophage activation (GO:0043032)2.81101653
86nucleoside diphosphate phosphorylation (GO:0006165)2.80742073
87axoneme assembly (GO:0035082)2.80269617
88nonmotile primary cilium assembly (GO:0035058)2.78827602
89mitotic sister chromatid cohesion (GO:0007064)2.78403458
90lung epithelium development (GO:0060428)2.76722309
91quaternary ammonium group transport (GO:0015697)2.76185933
92glycolytic process (GO:0006096)2.76113564
93centriole replication (GO:0007099)2.74784426
94glycerol metabolic process (GO:0006071)2.73914174
95establishment of apical/basal cell polarity (GO:0035089)2.73118832
96regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.71742946
97microtubule-based movement (GO:0007018)2.71278447
98protein refolding (GO:0042026)2.70760867
99positive regulation of dendritic spine morphogenesis (GO:0061003)2.69757335
100cilium organization (GO:0044782)2.69100664
101sensory perception of taste (GO:0050909)2.68183760
102pyrimidine nucleobase catabolic process (GO:0006208)2.66644334
103body morphogenesis (GO:0010171)2.64839936
104cellular component assembly involved in morphogenesis (GO:0010927)2.64759115
105secondary metabolite biosynthetic process (GO:0044550)2.64026386
106GTP biosynthetic process (GO:0006183)2.61311271
107establishment of nucleus localization (GO:0040023)2.60635241
108cilium assembly (GO:0042384)2.60362300
109lactate metabolic process (GO:0006089)2.59051691
110vocalization behavior (GO:0071625)2.58075036
111synapsis (GO:0007129)2.54627456
112regulation of meiosis I (GO:0060631)2.50484349
113polyamine metabolic process (GO:0006595)2.50144658
114interferon-gamma secretion (GO:0072643)2.49075299
115postsynaptic membrane organization (GO:0001941)2.48486090
116synaptic vesicle docking involved in exocytosis (GO:0016081)2.47449233
117meiotic cell cycle process (GO:1903046)2.46876832
118positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.46590884
119axon ensheathment in central nervous system (GO:0032291)2.44061998
120central nervous system myelination (GO:0022010)2.44061998
121gene silencing by RNA (GO:0031047)2.42289368
122urinary tract smooth muscle contraction (GO:0014848)2.40612887
123peristalsis (GO:0030432)2.40234434
124neuromuscular synaptic transmission (GO:0007274)2.36354744
125cerebellar granule cell differentiation (GO:0021707)2.31453120
126retinal rod cell development (GO:0046548)2.31204394
127nucleobase catabolic process (GO:0046113)2.30936904
128stress granule assembly (GO:0034063)2.29756727
129positive regulation of protein kinase C signaling (GO:0090037)2.27508667
130regulation of collateral sprouting (GO:0048670)2.27005524
131regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.26792830
132sympathetic nervous system development (GO:0048485)2.25287005
133ionotropic glutamate receptor signaling pathway (GO:0035235)2.25244199
134neuron recognition (GO:0008038)2.25051259
135iron coordination entity transport (GO:1901678)2.24847380
136reciprocal meiotic recombination (GO:0007131)2.24629435
137reciprocal DNA recombination (GO:0035825)2.24629435
138glutamate secretion (GO:0014047)2.24212859
139axonal fasciculation (GO:0007413)2.23894528
140nephron epithelium morphogenesis (GO:0072088)2.22831350
141nephron tubule morphogenesis (GO:0072078)2.22831350
142neuronal ion channel clustering (GO:0045161)2.22716095
143synaptic vesicle exocytosis (GO:0016079)2.21482437
144synaptic transmission, cholinergic (GO:0007271)2.19187090
145protein localization to synapse (GO:0035418)2.17634790
146spinal cord development (GO:0021510)2.16713832
147histone H3-K9 demethylation (GO:0033169)2.14710773
148asymmetric protein localization (GO:0008105)2.13498203
149segment specification (GO:0007379)2.13377673
150synaptic vesicle maturation (GO:0016188)2.13079108
151synaptic transmission, glutamatergic (GO:0035249)2.13041129
152sex differentiation (GO:0007548)2.12571150
153axon extension (GO:0048675)2.12232307
154phosphorelay signal transduction system (GO:0000160)2.10759970
155cranial nerve development (GO:0021545)2.08970113
156positive regulation of dendrite morphogenesis (GO:0050775)2.06965049
157synaptic vesicle endocytosis (GO:0048488)2.06493464
158regulation of short-term neuronal synaptic plasticity (GO:0048172)2.05654820
159respiratory system process (GO:0003016)2.05652460
160regulation of microtubule depolymerization (GO:0031114)2.03980820
161negative regulation of microtubule depolymerization (GO:0007026)2.02860006
162positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.02453723
163positive regulation of synapse maturation (GO:0090129)2.01809768
164cell wall macromolecule catabolic process (GO:0016998)15.3980222
165cell wall macromolecule metabolic process (GO:0044036)15.3980222
166fusion of sperm to egg plasma membrane (GO:0007342)14.6233708
167sperm motility (GO:0030317)12.9305521
168acrosome assembly (GO:0001675)11.8713454
169multicellular organism reproduction (GO:0032504)11.7157016
170sperm-egg recognition (GO:0035036)11.6926654
171acrosome reaction (GO:0007340)11.6011289
172plasma membrane fusion (GO:0045026)11.2050677
173cell-cell recognition (GO:0009988)10.4726882
174binding of sperm to zona pellucida (GO:0007339)10.2242848
175cilium or flagellum-dependent cell motility (GO:0001539)10.0515048

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.08048667
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.39391459
3EZH2_22144423_ChIP-Seq_EOC_Human3.77695058
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.69221049
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.40720386
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.39343773
7STAT6_21828071_ChIP-Seq_BEAS2B_Human3.36360195
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.96803206
9CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.90236267
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.63126733
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.60255212
12DROSHA_22980978_ChIP-Seq_HELA_Human2.59896595
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.37259264
14ERG_21242973_ChIP-ChIP_JURKAT_Human2.26164199
15CTCF_27219007_Chip-Seq_Bcells_Human2.21202070
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.12472204
17ZNF274_21170338_ChIP-Seq_K562_Hela2.11105609
18* SMC4_20622854_ChIP-Seq_HELA_Human2.05670981
19VDR_22108803_ChIP-Seq_LS180_Human2.00895147
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.98091569
21CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.98072125
22PCGF2_27294783_Chip-Seq_ESCs_Mouse1.96552240
23EZH2_27294783_Chip-Seq_ESCs_Mouse1.96037651
24GATA1_26923725_Chip-Seq_HPCs_Mouse1.94757287
25P68_20966046_ChIP-Seq_HELA_Human1.94720998
26KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.93484898
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.90632257
28EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.89750668
29TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.86712732
30CBX2_27304074_Chip-Seq_ESCs_Mouse1.84475739
31MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.82888409
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.81256578
33ELK4_26923725_Chip-Seq_MESODERM_Mouse1.75247153
34STAT1_17558387_ChIP-Seq_HELA_Human1.73362874
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.70447200
36SUZ12_27294783_Chip-Seq_ESCs_Mouse1.69428290
37GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.64364929
38KDM2B_26808549_Chip-Seq_REH_Human1.64325635
39EZH2_27304074_Chip-Seq_ESCs_Mouse1.61176230
40JARID2_20075857_ChIP-Seq_MESCs_Mouse1.60593191
41* KAP1_22055183_ChIP-Seq_ESCs_Mouse1.60347771
42RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.59991097
43CREB1_26743006_Chip-Seq_LNCaP_Human1.56613016
44REST_18959480_ChIP-ChIP_MESCs_Mouse1.52026337
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51905672
46TAL1_26923725_Chip-Seq_HPCs_Mouse1.51853827
47RARB_27405468_Chip-Seq_BRAIN_Mouse1.51737359
48MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.51213018
49* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.48254574
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47657657
51OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.47592612
52FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47528466
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.47386858
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.46020489
55* RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.45705525
56TAF15_26573619_Chip-Seq_HEK293_Human1.44437594
57WDR5_24793694_ChIP-Seq_LNCAP_Human1.44278946
58* SOX2_22085726_ChIP-Seq_NPCs_Mouse1.44102904
59GATA3_21867929_ChIP-Seq_CD8_Mouse1.44065130
60ZNF263_19887448_ChIP-Seq_K562_Human1.43618536
61* PHF8_20622854_ChIP-Seq_HELA_Human1.41437474
62SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.40519365
63FLI1_21867929_ChIP-Seq_TH2_Mouse1.39787933
64LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.38983219
65RNF2_27304074_Chip-Seq_ESCs_Mouse1.38913128
66TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37580127
67* KDM2B_26808549_Chip-Seq_K562_Human1.37463243
68ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36288016
69LXR_22292898_ChIP-Seq_THP-1_Human1.35899414
70PCGF2_27294783_Chip-Seq_NPCs_Mouse1.35797668
71SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.33780767
72IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32970618
73CBP_20019798_ChIP-Seq_JUKART_Human1.32970618
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.32458024
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31983006
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.31664081
77GF1_26923725_Chip-Seq_HPCs_Mouse1.31550648
78ESR2_21235772_ChIP-Seq_MCF-7_Human1.31363661
79RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29249865
80EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29249865
81XRN2_22483619_ChIP-Seq_HELA_Human1.29088859
82SALL1_21062744_ChIP-ChIP_HESCs_Human1.27259507
83SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27156883
84FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.27112953
85EED_16625203_ChIP-ChIP_MESCs_Mouse1.26716720
86P53_21459846_ChIP-Seq_SAOS-2_Human1.25757123
87REST_21632747_ChIP-Seq_MESCs_Mouse1.24382412
88CRX_20693478_ChIP-Seq_RETINA_Mouse1.23030417
89TET1_21451524_ChIP-Seq_MESCs_Mouse1.22955445
90JARID2_20064375_ChIP-Seq_MESCs_Mouse1.21326906
91E2F1_20622854_ChIP-Seq_HELA_Human1.21322676
92E2F1_17053090_ChIP-ChIP_MCF-7_Human1.20500170
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19347151
94PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.19133229
95CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18734135
96FOXP1_21924763_ChIP-Seq_HESCs_Human1.18572928
97GATA3_21867929_ChIP-Seq_TH1_Mouse1.17795715
98AR_21572438_ChIP-Seq_LNCaP_Human1.17482941
99CMYC_18555785_Chip-Seq_ESCs_Mouse1.16574095
100OCT4_18555785_Chip-Seq_ESCs_Mouse1.16322689
101TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.16207691
102ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15811987
103CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15762494
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15452096
105P53_22387025_ChIP-Seq_ESCs_Mouse1.14954064
106ERA_21632823_ChIP-Seq_H3396_Human1.14806251
107P300_18555785_Chip-Seq_ESCs_Mouse1.13373128
108ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.13108093
109ESR1_15608294_ChIP-ChIP_MCF-7_Human1.13017386
110RACK7_27058665_Chip-Seq_MCF-7_Human1.12986908
111PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10693196
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.10565857
113DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10474474
114CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10352461
115DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10290668
116* SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.09838331
117KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.09206057
118SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.07572407
119KLF4_18555785_Chip-Seq_ESCs_Mouse1.07275172
120SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.07130552
121RAD21_21589869_ChIP-Seq_MESCs_Mouse1.06962211
122OCT4_19829295_ChIP-Seq_ESCs_Human1.06838638
123ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.06354355
124RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05787985
125EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.05718841
126SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05381875
127SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05217583
128PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.04346958
129EZH2_27294783_Chip-Seq_NPCs_Mouse1.04289070
130SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03650772
131RUNX1_27514584_Chip-Seq_MCF-7_Human1.03586960
132CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03046033
133FOXM1_23109430_ChIP-Seq_U2OS_Human1.02621819
134GATA1_19941827_ChIP-Seq_MEL86_Mouse1.02092040
135SMAD4_21741376_ChIP-Seq_EPCs_Human1.01870425
136NFYB_21822215_ChIP-Seq_K562_Human1.01725805
137ESET_19884257_ChIP-Seq_ESCs_Mouse1.01713652
138OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01520350
139HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.00979184
140MYC_27129775_Chip-Seq_CORNEA_Mouse1.00735248
141ESRRB_18555785_Chip-Seq_ESCs_Mouse1.00510608
142SOX2_18555785_Chip-Seq_ESCs_Mouse1.00452622
143NFIB_24661679_ChIP-Seq_LUNG_Mouse1.00081207
144PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.99981433
145RNF2_27304074_Chip-Seq_NSC_Mouse0.99531849
146SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99304865
147EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99161956
148TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98393841
149MTF2_20144788_ChIP-Seq_MESCs_Mouse0.98341565
150RARB_24833708_ChIP-Seq_LIVER_Mouse0.97755295
151BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97345853
152* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97165588
153TET1_21490601_ChIP-Seq_MESCs_Mouse0.97091295
154SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.96502633
155SPI1_26923725_Chip-Seq_HPCs_Mouse0.96467126
156SA1_27219007_Chip-Seq_ERYTHROID_Human0.96455976
157TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95830455
158POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95830455
159ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95469382
160PU1_27457419_Chip-Seq_LIVER_Mouse0.95282712
161THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.94196742
162TBL1_22424771_ChIP-Seq_293T_Human0.94160366
163ELF1_20517297_ChIP-Seq_JURKAT_Human0.93995004
164GF1B_26923725_Chip-Seq_HPCs_Mouse0.93629590
165SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93471881
166SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.93429568
167CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93185489
168CTCF_20526341_ChIP-Seq_ESCs_Human0.93177060
169* TP63_22573176_ChIP-Seq_HFKS_Human0.92851441
170DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92753284
171OCT4_20526341_ChIP-Seq_ESCs_Human0.92472031
172RARA_24833708_ChIP-Seq_LIVER_Mouse0.92436709
173NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92338385
174PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91292324
175RING1B_27294783_Chip-Seq_ESCs_Mouse0.91125739
176E2F1_18555785_Chip-Seq_ESCs_Mouse0.91072189
177KDM5A_27292631_Chip-Seq_BREAST_Human0.90944896
178SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.90189273
179STAT3_18555785_Chip-Seq_ESCs_Mouse0.90135412
180CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89833908
181RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89546935
182SOX3_22085726_ChIP-Seq_NPCs_Mouse0.87136944
183SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86437865
184CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.85974066
185BCOR_27268052_Chip-Seq_Bcells_Human0.85534676
186SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.85399305
187BCL6_27268052_Chip-Seq_Bcells_Human0.85292447
188SA1_27219007_Chip-Seq_Bcells_Human0.85186712
189ESR1_21235772_ChIP-Seq_MCF-7_Human0.84445437

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.94822507
2MP0001929_abnormal_gametogenesis5.45149665
3MP0003136_yellow_coat_color4.06234573
4MP0008877_abnormal_DNA_methylation4.02849642
5MP0005423_abnormal_somatic_nervous3.90334710
6MP0002210_abnormal_sex_determination3.32389610
7MP0002161_abnormal_fertility/fecundity3.21687017
8MP0001188_hyperpigmentation3.21040753
9MP0001145_abnormal_male_reproductive2.80293517
10MP0001986_abnormal_taste_sensitivity2.67960136
11MP0005623_abnormal_meninges_morphology2.58157094
12MP0005670_abnormal_white_adipose2.52203550
13MP0003880_abnormal_central_pattern2.51686356
14MP0000653_abnormal_sex_gland2.44092995
15MP0004859_abnormal_synaptic_plasticity2.38594539
16MP0000778_abnormal_nervous_system2.22360029
17MP0002653_abnormal_ependyma_morphology2.17527417
18MP0005171_absent_coat_pigmentation2.09504535
19MP0005410_abnormal_fertilization16.3429431
20MP0005174_abnormal_tail_pigmentation1.99847043
21MP0002822_catalepsy1.91622807
22MP0002735_abnormal_chemical_nociception1.85896675
23MP0004233_abnormal_muscle_weight1.81383560
24MP0002638_abnormal_pupillary_reflex1.75650702
25MP0004133_heterotaxia1.72343662
26MP0003123_paternal_imprinting1.71202676
27MP0002160_abnormal_reproductive_system1.67035004
28MP0008789_abnormal_olfactory_epithelium1.61111541
29MP0006276_abnormal_autonomic_nervous1.58839811
30MP0002249_abnormal_larynx_morphology1.52530923
31MP0002184_abnormal_innervation1.45823862
32MP0000955_abnormal_spinal_cord1.44584797
33MP0005499_abnormal_olfactory_system1.44563159
34MP0005394_taste/olfaction_phenotype1.44563159
35MP0002734_abnormal_mechanical_nocicepti1.42707796
36MP0005083_abnormal_biliary_tract1.42188237
37MP0006292_abnormal_olfactory_placode1.41313704
38MP0004043_abnormal_pH_regulation1.41208776
39MP0000015_abnormal_ear_pigmentation1.39101832
40MP0001502_abnormal_circadian_rhythm1.36124740
41MP0001486_abnormal_startle_reflex1.35636231
42MP0009745_abnormal_behavioral_response1.35605357
43MP0002282_abnormal_trachea_morphology1.33317477
44MP0000566_synostosis1.30576694
45MP0002063_abnormal_learning/memory/cond1.30351845
46MP0002064_seizures1.28573223
47MP0002272_abnormal_nervous_system1.28164450
48MP0002572_abnormal_emotion/affect_behav1.28002118
49MP0010030_abnormal_orbit_morphology1.26876978
50MP0002234_abnormal_pharynx_morphology1.24524512
51MP0000751_myopathy1.24205833
52MP0001970_abnormal_pain_threshold1.21271073
53MP0003122_maternal_imprinting1.20364394
54MP0001485_abnormal_pinna_reflex1.19611027
55MP0002882_abnormal_neuron_morphology1.18617897
56MP0002102_abnormal_ear_morphology1.11472361
57MP0008995_early_reproductive_senescence1.10582898
58MP0003787_abnormal_imprinting1.06858075
59MP0003646_muscle_fatigue1.06626070
60MP0009046_muscle_twitch1.03492833
61MP0003121_genomic_imprinting1.02591990
62MP0001984_abnormal_olfaction1.01532604
63MP0002067_abnormal_sensory_capabilities1.01057600
64MP0002557_abnormal_social/conspecific_i1.00541120
65MP0000026_abnormal_inner_ear1.00423812
66MP0001529_abnormal_vocalization0.97492507
67MP0002233_abnormal_nose_morphology0.96912025
68MP0003693_abnormal_embryo_hatching0.94711240
69MP0001765_abnormal_ion_homeostasis0.92413840
70MP0000631_abnormal_neuroendocrine_gland0.91101105
71MP0003937_abnormal_limbs/digits/tail_de0.89956309
72MP0005647_abnormal_sex_gland0.89006574
73MP0002733_abnormal_thermal_nociception0.88876918
74MP0008057_abnormal_DNA_replication0.87690904
75MP0003938_abnormal_ear_development0.85801991
76MP0001346_abnormal_lacrimal_gland0.85659175
77MP0004381_abnormal_hair_follicle0.84428828
78MP0005167_abnormal_blood-brain_barrier0.83980691
79MP0005389_reproductive_system_phenotype0.83825303
80MP0009780_abnormal_chondrocyte_physiolo0.83641158
81MP0001286_abnormal_eye_development0.82586544
82MP0001299_abnormal_eye_distance/0.82313460
83MP0001963_abnormal_hearing_physiology0.81137812
84MP0001293_anophthalmia0.80278163
85MP0002066_abnormal_motor_capabilities/c0.79506877
86MP0001348_abnormal_lacrimal_gland0.79499316
87MP0000579_abnormal_nail_morphology0.79305502
88MP0001905_abnormal_dopamine_level0.78009970
89MP0002697_abnormal_eye_size0.73712930
90MP0003119_abnormal_digestive_system0.73709574
91MP0002116_abnormal_craniofacial_bone0.73494730
92MP0004924_abnormal_behavior0.72922299
93MP0005386_behavior/neurological_phenoty0.72922299
94MP0002938_white_spotting0.72583523
95MP0000049_abnormal_middle_ear0.72099725
96MP0003011_delayed_dark_adaptation0.71517711
97MP0001879_abnormal_lymphatic_vessel0.66551813
98MP0002736_abnormal_nociception_after0.60791015
99MP0004272_abnormal_basement_membrane0.60106689
100MP0005551_abnormal_eye_electrophysiolog0.58627545
101MP0008058_abnormal_DNA_repair0.54374384
102MP0005253_abnormal_eye_physiology0.54270919
103MP0001324_abnormal_eye_pigmentation0.53875759
104MP0005636_abnormal_mineral_homeostasis0.52452357
105MP0005391_vision/eye_phenotype0.51652205
106MP0010368_abnormal_lymphatic_system0.49702323
107MP0003115_abnormal_respiratory_system0.46520583
108MP0004036_abnormal_muscle_relaxation0.46106641
109MP0001968_abnormal_touch/_nociception0.41893768
110MP0000358_abnormal_cell_content/0.41491794
111MP0003699_abnormal_female_reproductive0.41246980
112MP0003633_abnormal_nervous_system0.41205850
113MP0005666_abnormal_adipose_tissue0.38632853
114MP0002092_abnormal_eye_morphology0.38425474
115MP0005409_darkened_coat_color0.38252180
116MP0003329_amyloid_beta_deposits0.37021627
117MP0002971_abnormal_brown_adipose0.34317291
118MP0006036_abnormal_mitochondrial_physio0.34066833
119MP0002269_muscular_atrophy0.33711546
120MP0003861_abnormal_nervous_system0.33472616
121MP0008569_lethality_at_weaning0.32658946
122MP0004811_abnormal_neuron_physiology0.32173357
123MP0003786_premature_aging0.31887180
124MP0002295_abnormal_pulmonary_circulatio0.31809120
125MP0002152_abnormal_brain_morphology0.31043239
126MP0003948_abnormal_gas_homeostasis0.30182174
127MP0009697_abnormal_copulation0.29649732
128MP0005377_hearing/vestibular/ear_phenot0.27898123
129MP0003878_abnormal_ear_physiology0.27898123
130MP0002139_abnormal_hepatobiliary_system0.27731795
131MP0001119_abnormal_female_reproductive0.27323519
132MP0004270_analgesia0.26959734
133MP0006035_abnormal_mitochondrial_morpho0.26560165
134MP0002928_abnormal_bile_duct0.26244313
135MP0001730_embryonic_growth_arrest0.25761988
136MP0003950_abnormal_plasma_membrane0.25455905
137MP0002405_respiratory_system_inflammati0.25066910
138MP0006054_spinal_hemorrhage0.24525554
139MP0004084_abnormal_cardiac_muscle0.24092289
140MP0003279_aneurysm0.23908574
141MP0003631_nervous_system_phenotype0.23406831
142MP0005195_abnormal_posterior_eye0.23261112
143MP0009278_abnormal_bone_marrow0.23107193
144MP0004484_altered_response_of0.22893521
145MP0005535_abnormal_body_temperature0.22846710
146MP0004742_abnormal_vestibular_system0.22306485
147MP0000249_abnormal_blood_vessel0.20705333
148MP0001545_abnormal_hematopoietic_system0.20696164
149MP0005397_hematopoietic_system_phenotyp0.20696164
150MP0003942_abnormal_urinary_system0.20403315
151MP0003635_abnormal_synaptic_transmissio0.19190389
152MP0000462_abnormal_digestive_system0.18989583
153MP0004019_abnormal_vitamin_homeostasis0.18968791
154MP0002084_abnormal_developmental_patter0.18428106
155MP0009115_abnormal_fat_cell0.17994959
156MP0010630_abnormal_cardiac_muscle0.17631655
157MP0000432_abnormal_head_morphology0.17105801
158MP0003879_abnormal_hair_cell0.17050728
159MP0002169_no_abnormal_phenotype0.17007274
160MP0001919_abnormal_reproductive_system0.16932754
161MP0001614_abnormal_blood_vessel0.16737920
162MP0002873_normal_phenotype0.16668007
163MP0002229_neurodegeneration0.16392274
164MP0001440_abnormal_grooming_behavior0.15360892
165MP0008875_abnormal_xenobiotic_pharmacok0.15342616
166MP0002752_abnormal_somatic_nervous0.15214283
167MP0000534_abnormal_ureter_morphology0.15080845
168MP0000013_abnormal_adipose_tissue0.14869383
169MP0002925_abnormal_cardiovascular_devel0.14691983

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.43159443
2Abnormal respiratory motile cilium morphology (HP:0005938)9.43159443
3Abnormal respiratory motile cilium physiology (HP:0012261)9.30956630
4Rhinitis (HP:0012384)7.57391582
5Abnormal ciliary motility (HP:0012262)7.50703662
6Chronic bronchitis (HP:0004469)7.22808857
7Infertility (HP:0000789)6.47477295
8Nasal polyposis (HP:0100582)6.29088157
9Abnormality of the nasal mucosa (HP:0000433)5.32057730
10Bronchiectasis (HP:0002110)4.35850567
11Bronchitis (HP:0012387)4.34371423
12Male infertility (HP:0003251)4.19233077
13Nephronophthisis (HP:0000090)3.67869801
14Abnormal spermatogenesis (HP:0008669)3.30169879
15Recurrent sinusitis (HP:0011108)3.27101722
16Rib fusion (HP:0000902)3.23395703
17Recurrent otitis media (HP:0000403)3.11016922
18Medial flaring of the eyebrow (HP:0010747)3.11000013
19Abnormality of the renal medulla (HP:0100957)2.74221385
20Myokymia (HP:0002411)2.69664278
21Dyschromatopsia (HP:0007641)2.63059216
22Congenital stationary night blindness (HP:0007642)2.58140366
23Pancreatic fibrosis (HP:0100732)2.51283605
24Abnormality of midbrain morphology (HP:0002418)2.49194814
25Molar tooth sign on MRI (HP:0002419)2.49194814
26Chronic hepatic failure (HP:0100626)2.47425636
27Impulsivity (HP:0100710)2.46143533
28Amblyopia (HP:0000646)2.46018472
29Recurrent bronchitis (HP:0002837)2.42079800
30Tubulointerstitial nephritis (HP:0001970)2.40673087
31Choroideremia (HP:0001139)2.40331629
32Azoospermia (HP:0000027)2.34966655
33Decreased central vision (HP:0007663)2.34658708
34Exercise-induced muscle cramps (HP:0003710)2.28216125
35Aplasia/Hypoplasia of the lens (HP:0008063)2.26787210
36Tubular atrophy (HP:0000092)2.23572146
37Gait imbalance (HP:0002141)2.21667267
38Gonadotropin excess (HP:0000837)2.21226143
39Occipital encephalocele (HP:0002085)2.20014265
40Congenital primary aphakia (HP:0007707)2.19916836
41Lip pit (HP:0100267)2.19074324
42Epileptic encephalopathy (HP:0200134)2.15151449
43True hermaphroditism (HP:0010459)2.14107425
44Fetal akinesia sequence (HP:0001989)2.11347992
45Oligodactyly (hands) (HP:0001180)2.07818304
46Bony spicule pigmentary retinopathy (HP:0007737)2.03688753
47Facial hemangioma (HP:0000329)2.03153377
48Cholecystitis (HP:0001082)2.02978542
49Abnormal gallbladder physiology (HP:0012438)2.02978542
50Patellar aplasia (HP:0006443)2.02924063
51Dynein arm defect of respiratory motile cilia (HP:0012255)13.4432900
52Absent/shortened dynein arms (HP:0200106)13.4432900
53Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8936416
54Chronic sinusitis (HP:0011109)1.99196078
55Tubulointerstitial abnormality (HP:0001969)1.98810330
56Hemorrhage of the eye (HP:0011885)1.98072129
57Nephrogenic diabetes insipidus (HP:0009806)1.96251821
58Type II lissencephaly (HP:0007260)1.94675968
59Pancreatic cysts (HP:0001737)1.89685216
60Turricephaly (HP:0000262)1.87442920
61Atelectasis (HP:0100750)1.85428127
62Aplasia/Hypoplasia of the patella (HP:0006498)1.84650711
63Preaxial hand polydactyly (HP:0001177)1.82188688
64Hyperinsulinemic hypoglycemia (HP:0000825)1.73862737
65Abnormality of the labia minora (HP:0012880)1.73186845
66Congenital hepatic fibrosis (HP:0002612)1.70580588
67Akinesia (HP:0002304)1.70333313
68Testicular atrophy (HP:0000029)1.70214948
69Vaginal fistula (HP:0004320)1.70024400
70Abnormality of the nasal septum (HP:0000419)1.68717153
71Heterotopia (HP:0002282)1.68028198
72Anencephaly (HP:0002323)1.67440032
73Hemiparesis (HP:0001269)1.65638309
74Decreased electroretinogram (ERG) amplitude (HP:0000654)1.65305556
75Poikiloderma (HP:0001029)1.64564397
76Vaginal atresia (HP:0000148)1.64447855
77Stage 5 chronic kidney disease (HP:0003774)1.64135163
78Hypoplasia of the pons (HP:0012110)1.62682511
79Broad-based gait (HP:0002136)1.62304991
80Intestinal fistula (HP:0100819)1.62167336
81Hypoplasia of the capital femoral epiphysis (HP:0003090)1.61877779
82Poor coordination (HP:0002370)1.61685343
83Genital tract atresia (HP:0001827)1.60424626
84Postaxial foot polydactyly (HP:0001830)1.59470013
85Easy fatigability (HP:0003388)1.58842508
86Spastic tetraparesis (HP:0001285)1.57579555
87Decreased circulating renin level (HP:0003351)1.57211637
88Polydipsia (HP:0001959)1.57070869
89Abnormal drinking behavior (HP:0030082)1.57070869
90Hepatoblastoma (HP:0002884)1.56204797
91Anophthalmia (HP:0000528)1.55111158
92Abnormality of the neuromuscular junction (HP:0003398)1.54820914
93Fatigable weakness (HP:0003473)1.54820914
94Abnormality of saccadic eye movements (HP:0000570)1.54475582
95Tubulointerstitial fibrosis (HP:0005576)1.54473976
96Median cleft lip (HP:0000161)1.54042004
97Birth length less than 3rd percentile (HP:0003561)1.54008791
98Postaxial hand polydactyly (HP:0001162)1.53581210
99Absent speech (HP:0001344)1.53560189
100Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.53169559
101Optic nerve coloboma (HP:0000588)1.51887788
102Sleep apnea (HP:0010535)1.50101876
103Rectovaginal fistula (HP:0000143)1.48814606
104Rectal fistula (HP:0100590)1.48814606
105Hyperventilation (HP:0002883)1.48361350
106Spastic gait (HP:0002064)1.48100391
107Meningocele (HP:0002435)1.47837060
108Abnormality of the pons (HP:0007361)1.47577440
109Abnormality of renal excretion (HP:0011036)1.46926356
110Oligodactyly (HP:0012165)1.46594033
111Ulnar bowing (HP:0003031)1.45744676
112Aplasia of the musculature (HP:0100854)1.45424253
113Annular pancreas (HP:0001734)1.43755656
114Neurofibrillary tangles (HP:0002185)1.43258258
115Type 2 muscle fiber atrophy (HP:0003554)1.43173371
116Sclerocornea (HP:0000647)1.43005601
117Hypoplasia of the brainstem (HP:0002365)1.42462931
118Aplasia/Hypoplasia of the brainstem (HP:0007362)1.42462931
119Abnormal number of incisors (HP:0011064)1.40773077
120Ankle clonus (HP:0011448)1.40639292
121Multicystic kidney dysplasia (HP:0000003)1.40590048
122Congenital malformation of the right heart (HP:0011723)1.39228766
123Double outlet right ventricle (HP:0001719)1.39228766
124Supernumerary spleens (HP:0009799)1.36854611
125Abnormality of the renal cortex (HP:0011035)1.36494664
126Bundle branch block (HP:0011710)1.36410100
127Attenuation of retinal blood vessels (HP:0007843)1.36027801
128Oculomotor apraxia (HP:0000657)1.35635257
129Hyperphosphatemia (HP:0002905)1.34663649
130Cerebellar dysplasia (HP:0007033)1.33209843
131Facial cleft (HP:0002006)1.30753835
132Abnormality of the dental root (HP:0006486)1.30710414
133Taurodontia (HP:0000679)1.30710414
134Abnormality of permanent molar morphology (HP:0011071)1.30710414
135Bell-shaped thorax (HP:0001591)1.30082785
136Renal dysplasia (HP:0000110)1.28653370
137Short ribs (HP:0000773)1.27611790
138Abnormal biliary tract physiology (HP:0012439)1.27505117
139Bile duct proliferation (HP:0001408)1.27505117
140Absent epiphyses (HP:0010577)1.26259052
141Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.26259052
142Sensory axonal neuropathy (HP:0003390)1.24862151
143Abnormality of ocular smooth pursuit (HP:0000617)1.21219140
144Abnormality of dentin (HP:0010299)1.21105297
145Abnormality of the dental pulp (HP:0006479)1.20102981
146Abnormality of molar morphology (HP:0011070)1.19763522
147Abnormality of molar (HP:0011077)1.19763522
148Cerebral inclusion bodies (HP:0100314)1.16367603
149Absent eyebrow (HP:0002223)1.16328473
150Macular degeneration (HP:0000608)1.16326655
151Pancreatic islet-cell hyperplasia (HP:0004510)1.15956362
152Cystic liver disease (HP:0006706)1.15680577
153Asymmetric septal hypertrophy (HP:0001670)1.15667064
154Fibular hypoplasia (HP:0003038)1.15401505
155Retinal dysplasia (HP:0007973)1.14693913
156Abnormal urine output (HP:0012590)1.14568227

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.31226907
2PDK48.31226907
3TESK15.44130728
4PDK25.33706197
5PRKD34.32021176
6ICK4.08692149
7MST1R3.34874791
8PNCK3.10663194
9PTK2B2.41099155
10EPHA22.27410923
11MARK12.26111582
12EPHA42.18454816
13STK391.97642643
14WNK41.94690423
15LATS11.93979362
16SIK21.81088387
17NTRK31.75239551
18MET1.72745474
19CAMK1D1.58644620
20NEK21.49593411
21DYRK1B1.48706906
22STK381.40396350
23BCR1.32232738
24KDR1.28112835
25MAPK131.26051944
26CDK191.25607337
27IRAK11.24704105
28CASK1.23219924
29DYRK21.11213574
30TRIM281.10500860
31PDK11.08903795
32DYRK1A1.08405941
33TSSK61.07154494
34MINK11.06146919
35MAP3K41.05317684
36CDK31.03263836
37CAMK1G1.01982925
38PIM20.98843163
39OXSR10.98566534
40WNK10.98266242
41EEF2K0.95771078
42BRSK20.93607498
43MAP3K90.91436766
44DYRK30.89860481
45MAP2K70.88898101
46IRAK20.86115018
47NTRK20.84616146
48BMPR1B0.82619736
49MKNK20.81488598
50TRIB30.80487044
51TYRO30.79754340
52UHMK10.77891122
53NME10.76372190
54MAPK150.75845978
55CSNK1G20.70706867
56RIPK40.70527290
57MUSK0.69847414
58LMTK20.66896741
59MAP3K70.65837138
60PHKG20.63174306
61PHKG10.63174306
62MAP2K40.62599880
63CSNK1A1L0.62160950
64PLK40.61340148
65STK160.61161337
66CSNK1E0.60140368
67CSNK1G30.59736080
68CDK50.59627645
69CHEK20.58619337
70SGK2230.58215221
71SGK4940.58215221
72MAPK100.57584813
73PINK10.57477987
74PDPK10.57123656
75PASK0.54606594
76PRKCH0.54451449
77RPS6KA20.53686428
78CSNK1G10.53665671
79SIK10.53464764
80CDK120.52636348
81PRKDC0.52384431
82PAK60.52045250
83CDK20.51898915
84CCNB10.51441314
85CDK10.51271529
86MAPKAPK50.50959105
87DAPK20.49678844
88LATS20.49558714
89TESK20.49068176
90PAK30.47041562
91CDK80.44042893
92AURKA0.43351606
93STK30.43093019
94MAP2K60.41833475
95PRKCG0.41709249
96PRKCI0.41127141
97TIE10.40604703
98MAPK140.39982318
99RIPK10.39128091
100CAMKK10.38619911
101YES10.38477379
102BRSK10.37656033
103MARK30.32978040
104TTK0.32483392
105PRKG20.31538047
106WEE10.31263994
107CHEK10.30407158
108PAK10.25332430
109STK110.24059044
110GRK10.22791735
111MAP3K100.22519762
112PRKAA10.21912991
113MAP2K20.21098486
114ATM0.19610624
115PRKCQ0.18815594
116PAK20.16829634
117PRKCZ0.15386153
118CDK140.15331931
119MTOR0.15322227
120GRK50.14333556
121TBK10.13767406
122CDK150.12468996
123RPS6KB10.11398359
124CDK180.09509591
125EGFR0.08804882
126PRKAA20.08734620
127MARK20.08699753
128CDK11A0.08531812
129PRKG10.08276239
130CSNK1D0.07547954
131PLK10.07323211
132CSNK2A10.07255934
133PAK40.07205262
134STK38L0.07106427
135RPS6KA10.06607848
136STK100.06381549
137CAMK2A0.06269920
138PRKACG0.06011851
139PDGFRB0.05848087
140PKN10.05770116
141PRKCD0.05636329
142PRKCA0.05620602
143PRKCB0.04811923
144PLK20.04498092
145EPHB20.04025228
146GSK3B0.03670272
147NEK60.03430806
148MAPK80.02970125
149CAMK10.02360638
150INSRR0.02285838
151FGR0.02112723
152CAMKK20.01973400
153CSNK2A20.00937196
154CDK60.00024262
155ATR-0.0072463
156CDC7-0.0048964
157PIM1-0.0006508

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.19289360
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.14991277
3Vitamin B6 metabolism_Homo sapiens_hsa007503.58373569
4Pyruvate metabolism_Homo sapiens_hsa006203.24640374
5Nicotine addiction_Homo sapiens_hsa050333.05545563
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.88466149
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.88233878
8Propanoate metabolism_Homo sapiens_hsa006402.73210551
9Linoleic acid metabolism_Homo sapiens_hsa005912.71986921
10Glucagon signaling pathway_Homo sapiens_hsa049222.63091527
11Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.55265553
12Glycosaminoglycan degradation_Homo sapiens_hsa005312.51095366
13Sulfur relay system_Homo sapiens_hsa041222.46944650
14Basal transcription factors_Homo sapiens_hsa030222.46571816
15Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.44149609
16Glycerolipid metabolism_Homo sapiens_hsa005612.11895168
17Carbohydrate digestion and absorption_Homo sapiens_hsa049732.04424801
18Selenocompound metabolism_Homo sapiens_hsa004501.97835585
19PPAR signaling pathway_Homo sapiens_hsa033201.91846558
20Phenylalanine metabolism_Homo sapiens_hsa003601.91211047
21Glycerophospholipid metabolism_Homo sapiens_hsa005641.80758653
22Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.79215059
23Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.77903871
24Dorso-ventral axis formation_Homo sapiens_hsa043201.76694193
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.75449242
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.71574794
27Oocyte meiosis_Homo sapiens_hsa041141.71126842
28Mineral absorption_Homo sapiens_hsa049781.68982938
29Pentose phosphate pathway_Homo sapiens_hsa000301.64186034
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.61424125
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.61166818
32Ether lipid metabolism_Homo sapiens_hsa005651.59378827
33Amphetamine addiction_Homo sapiens_hsa050311.58677020
34beta-Alanine metabolism_Homo sapiens_hsa004101.55701466
35Phototransduction_Homo sapiens_hsa047441.52165691
36Cardiac muscle contraction_Homo sapiens_hsa042601.40290686
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.39194603
38Fatty acid degradation_Homo sapiens_hsa000711.30030674
39Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.28525130
40Steroid biosynthesis_Homo sapiens_hsa001001.27881708
41Axon guidance_Homo sapiens_hsa043601.27133948
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26413955
43Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.26106725
44Basal cell carcinoma_Homo sapiens_hsa052171.24235172
45Histidine metabolism_Homo sapiens_hsa003401.22768911
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.22648238
47Fatty acid metabolism_Homo sapiens_hsa012121.22501209
48Fructose and mannose metabolism_Homo sapiens_hsa000511.21673984
49Morphine addiction_Homo sapiens_hsa050321.21540398
50Lysine degradation_Homo sapiens_hsa003101.19602885
51Fat digestion and absorption_Homo sapiens_hsa049751.19321107
52Huntingtons disease_Homo sapiens_hsa050161.18732642
53Tyrosine metabolism_Homo sapiens_hsa003501.18612874
54GABAergic synapse_Homo sapiens_hsa047271.16580913
55Hippo signaling pathway_Homo sapiens_hsa043901.16354902
56Renin secretion_Homo sapiens_hsa049241.12714949
57Carbon metabolism_Homo sapiens_hsa012001.12197035
58Circadian rhythm_Homo sapiens_hsa047101.11890956
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.07271517
60Bile secretion_Homo sapiens_hsa049761.06991494
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.05286322
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.04999992
63Arginine and proline metabolism_Homo sapiens_hsa003300.97728218
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97134479
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.96164525
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.93694867
67Hedgehog signaling pathway_Homo sapiens_hsa043400.92449389
68Fanconi anemia pathway_Homo sapiens_hsa034600.92309091
69Insulin secretion_Homo sapiens_hsa049110.92095186
70Notch signaling pathway_Homo sapiens_hsa043300.90855310
71Purine metabolism_Homo sapiens_hsa002300.88139071
72Melanogenesis_Homo sapiens_hsa049160.85295432
73Long-term potentiation_Homo sapiens_hsa047200.84382552
74Arginine biosynthesis_Homo sapiens_hsa002200.83225402
75Collecting duct acid secretion_Homo sapiens_hsa049660.82898355
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82512714
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.82044670
78Dopaminergic synapse_Homo sapiens_hsa047280.81942755
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.81023606
80Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.79492623
81Glutathione metabolism_Homo sapiens_hsa004800.79229816
82Antigen processing and presentation_Homo sapiens_hsa046120.78745283
83Sphingolipid metabolism_Homo sapiens_hsa006000.78229783
84Chemical carcinogenesis_Homo sapiens_hsa052040.77579731
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.75632090
86Estrogen signaling pathway_Homo sapiens_hsa049150.73888038
87Homologous recombination_Homo sapiens_hsa034400.71183651
88Thyroid hormone synthesis_Homo sapiens_hsa049180.69955132
89Cholinergic synapse_Homo sapiens_hsa047250.69803922
90Protein digestion and absorption_Homo sapiens_hsa049740.69225488
91Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69195182
92Nitrogen metabolism_Homo sapiens_hsa009100.68329507
93Tight junction_Homo sapiens_hsa045300.67169787
94Biosynthesis of amino acids_Homo sapiens_hsa012300.64301110
95Butanoate metabolism_Homo sapiens_hsa006500.62927006
96Arachidonic acid metabolism_Homo sapiens_hsa005900.62269093
97Cell cycle_Homo sapiens_hsa041100.62023392
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61527462
99Systemic lupus erythematosus_Homo sapiens_hsa053220.59249207
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.58711060
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58467417
102Ovarian steroidogenesis_Homo sapiens_hsa049130.58177090
103Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58074169
104Calcium signaling pathway_Homo sapiens_hsa040200.57727264
105Legionellosis_Homo sapiens_hsa051340.57485348
106Non-homologous end-joining_Homo sapiens_hsa034500.56020997
107Regulation of autophagy_Homo sapiens_hsa041400.54446821
108Primary bile acid biosynthesis_Homo sapiens_hsa001200.52169168
109Parkinsons disease_Homo sapiens_hsa050120.50962752
110Pancreatic secretion_Homo sapiens_hsa049720.50188643
111Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.49575217
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.49091889
113RNA transport_Homo sapiens_hsa030130.48894497
114N-Glycan biosynthesis_Homo sapiens_hsa005100.48786116
115Serotonergic synapse_Homo sapiens_hsa047260.48495744
116Gastric acid secretion_Homo sapiens_hsa049710.48219526
117Synaptic vesicle cycle_Homo sapiens_hsa047210.48031835
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47908445
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47814733
120Inositol phosphate metabolism_Homo sapiens_hsa005620.47010773
121VEGF signaling pathway_Homo sapiens_hsa043700.46864590
122Base excision repair_Homo sapiens_hsa034100.46120151
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45073509
124HIF-1 signaling pathway_Homo sapiens_hsa040660.43705724
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42864538
126Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42315746
127Vascular smooth muscle contraction_Homo sapiens_hsa042700.42082708
128mRNA surveillance pathway_Homo sapiens_hsa030150.41623350
129Salivary secretion_Homo sapiens_hsa049700.41396698
130Circadian entrainment_Homo sapiens_hsa047130.41267819
131ABC transporters_Homo sapiens_hsa020100.40965520
132Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40765067
133cAMP signaling pathway_Homo sapiens_hsa040240.39191709
134Metabolic pathways_Homo sapiens_hsa011000.39087159
135Endocytosis_Homo sapiens_hsa041440.38918699
136Wnt signaling pathway_Homo sapiens_hsa043100.37798258
137Taste transduction_Homo sapiens_hsa047420.37347361
138Renin-angiotensin system_Homo sapiens_hsa046140.37065965
139AMPK signaling pathway_Homo sapiens_hsa041520.33900879
140Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.32045569
141Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.30035105
142Glutamatergic synapse_Homo sapiens_hsa047240.27888859
143Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24919308
144B cell receptor signaling pathway_Homo sapiens_hsa046620.22398263
145Cocaine addiction_Homo sapiens_hsa050300.22006341
146Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.21100100
147Alcoholism_Homo sapiens_hsa050340.16165487
148Complement and coagulation cascades_Homo sapiens_hsa046100.14545335
149Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13448613
150Aldosterone synthesis and secretion_Homo sapiens_hsa049250.13148048
151Retinol metabolism_Homo sapiens_hsa008300.10281663

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »