ZC3HAV1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.00113012
2antigen processing and presentation of endogenous antigen (GO:0019883)4.44493957
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.37699469
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.37699469
5positive regulation of gamma-delta T cell activation (GO:0046645)4.26722237
6neutrophil activation involved in immune response (GO:0002283)4.23219585
7* positive regulation of interferon-alpha production (GO:0032727)4.22506269
8response to type I interferon (GO:0034340)4.19606235
9cellular response to type I interferon (GO:0071357)4.17266215
10type I interferon signaling pathway (GO:0060337)4.17266215
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.02415687
12negative regulation of cell killing (GO:0031342)4.02415687
13* regulation of interferon-alpha production (GO:0032647)4.00497348
14positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.86812404
15immunoglobulin mediated immune response (GO:0016064)3.85632421
16response to interleukin-15 (GO:0070672)3.71509386
17tolerance induction (GO:0002507)3.67950379
18response to peptidoglycan (GO:0032494)3.65624442
19cellular response to interferon-beta (GO:0035458)3.56833409
20cellular response to interleukin-15 (GO:0071350)3.54637928
21positive regulation of natural killer cell differentiation (GO:0032825)3.53695443
22myeloid dendritic cell activation (GO:0001773)3.45923920
23regulation of interleukin-12 biosynthetic process (GO:0045075)3.43161726
24negative regulation of T cell mediated immunity (GO:0002710)3.42308545
25neutrophil activation (GO:0042119)3.39363056
26negative regulation of interleukin-12 production (GO:0032695)3.37380321
27interferon-gamma-mediated signaling pathway (GO:0060333)3.37291606
28granulocyte activation (GO:0036230)3.36561718
29myeloid dendritic cell differentiation (GO:0043011)3.36430138
30response to muramyl dipeptide (GO:0032495)3.36040102
31interferon-gamma production (GO:0032609)3.34875094
32cellular response to virus (GO:0098586)3.34822074
33regulation of regulatory T cell differentiation (GO:0045589)3.34012592
34response to interferon-beta (GO:0035456)3.33575357
35T cell migration (GO:0072678)3.33003848
36regulation of T-helper 1 cell differentiation (GO:0045625)3.31699948
37response to interferon-alpha (GO:0035455)3.29922660
38CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.27702626
39NIK/NF-kappaB signaling (GO:0038061)3.23815873
40positive T cell selection (GO:0043368)3.22639740
41natural killer cell mediated immunity (GO:0002228)3.21941443
42natural killer cell mediated cytotoxicity (GO:0042267)3.21941443
43positive regulation of granulocyte differentiation (GO:0030854)3.21635327
44cellular response to exogenous dsRNA (GO:0071360)3.20385264
45positive regulation of antigen processing and presentation (GO:0002579)3.19809069
46regulation of alpha-beta T cell proliferation (GO:0046640)3.19743422
47* negative regulation of viral genome replication (GO:0045071)3.18561305
48B cell mediated immunity (GO:0019724)3.18149026
49defense response to protozoan (GO:0042832)3.16710690
50negative thymic T cell selection (GO:0045060)3.16402276
51negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.15782834
52negative regulation of T-helper cell differentiation (GO:0045623)3.15782834
53negative T cell selection (GO:0043383)3.14328585
54positive regulation by symbiont of host defense response (GO:0052509)3.13221121
55modulation by symbiont of host defense response (GO:0052031)3.13221121
56modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.13221121
57modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.13221121
58positive regulation by organism of defense response of other organism involved in symbiotic interact3.13221121
59modulation by symbiont of host immune response (GO:0052553)3.13221121
60positive thymic T cell selection (GO:0045059)3.12764058
61negative regulation of myeloid cell apoptotic process (GO:0033033)3.11929537
62positive regulation of interleukin-12 production (GO:0032735)3.10683095
63cellular response to zinc ion (GO:0071294)3.10116478
64positive regulation of alpha-beta T cell proliferation (GO:0046641)3.09068343
65* positive regulation of interferon-beta production (GO:0032728)3.08352772
66lipopolysaccharide-mediated signaling pathway (GO:0031663)3.07564465
67activated T cell proliferation (GO:0050798)3.07463772
68positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.05582779
69regulation of dendritic cell antigen processing and presentation (GO:0002604)3.05104453
70hepatocyte apoptotic process (GO:0097284)3.04694830
71regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.04136046
72necroptotic process (GO:0070266)3.03843730
73Arp2/3 complex-mediated actin nucleation (GO:0034314)3.02663227
74regulation of gamma-delta T cell activation (GO:0046643)3.02469140
75T cell selection (GO:0045058)3.01824594
76regulation of B cell receptor signaling pathway (GO:0050855)3.01390078
77response to protozoan (GO:0001562)3.00009889
78respiratory burst (GO:0045730)2.98714633
79positive regulation of interleukin-2 production (GO:0032743)2.98561008
80leukocyte aggregation (GO:0070486)2.98486754
81positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.94072169
82regulation of gamma-delta T cell differentiation (GO:0045586)2.93960074
83positive regulation of isotype switching (GO:0045830)2.93866471
84regulation of chronic inflammatory response (GO:0002676)2.90354440
85macrophage activation involved in immune response (GO:0002281)2.87739999
86DNA deamination (GO:0045006)2.86320309
87regulation of activation of Janus kinase activity (GO:0010533)2.85861240
88regulation of interleukin-2 biosynthetic process (GO:0045076)2.84404384
89regulation of interferon-beta biosynthetic process (GO:0045357)2.83854299
90negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.83701277
91positive regulation of B cell differentiation (GO:0045579)2.81517788
92natural killer cell activation (GO:0030101)2.81298175
93* regulation of interferon-beta production (GO:0032648)2.81179344
94regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.80632584
95alpha-beta T cell differentiation (GO:0046632)2.80312667
96hydrogen peroxide biosynthetic process (GO:0050665)2.79918996
97thymic T cell selection (GO:0045061)2.79331872
98positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.78573788
99regulation of antigen processing and presentation (GO:0002577)2.78329043
100regulation of response to interferon-gamma (GO:0060330)2.78011785
101positive regulation of B cell mediated immunity (GO:0002714)2.77836314
102positive regulation of immunoglobulin mediated immune response (GO:0002891)2.77836314
103regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.77424111
104positive regulation of humoral immune response (GO:0002922)2.76063797
105negative regulation of B cell proliferation (GO:0030889)2.75943804
106alpha-beta T cell activation (GO:0046631)2.73716883
107programmed necrotic cell death (GO:0097300)2.73533508
108positive regulation of cytokine biosynthetic process (GO:0042108)2.73257310
109regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.71497817
110regulation of natural killer cell mediated immunity (GO:0002715)2.71318865
111regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.71318865
112mast cell activation (GO:0045576)2.71282827
113regulation of alpha-beta T cell activation (GO:0046634)2.70845648
114positive regulation of DNA recombination (GO:0045911)2.70172070
115regulation of hypersensitivity (GO:0002883)2.69552125
116interferon-gamma secretion (GO:0072643)2.69489521
117T cell lineage commitment (GO:0002360)2.69215971
118regulation of T cell mediated cytotoxicity (GO:0001914)2.69136875
119regulation of B cell differentiation (GO:0045577)2.68424821
120reactive oxygen species biosynthetic process (GO:1903409)2.67801351
121dendritic cell differentiation (GO:0097028)2.67765082
122positive regulation of defense response to virus by host (GO:0002230)2.67691041
123* regulation of viral genome replication (GO:0045069)2.66923913
124* defense response to virus (GO:0051607)2.66206334
125T cell activation involved in immune response (GO:0002286)2.65134081
126regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.63803288
127myeloid cell activation involved in immune response (GO:0002275)2.63662080
128monocyte chemotaxis (GO:0002548)2.63268734
129antigen processing and presentation via MHC class Ib (GO:0002475)2.63063160
130JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.62919842
131regulation of type I interferon-mediated signaling pathway (GO:0060338)2.62842465
132T-helper 1 type immune response (GO:0042088)2.62632434
133superoxide anion generation (GO:0042554)2.62447692
134positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.62323678
135positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.62215874
136regulation of T cell tolerance induction (GO:0002664)2.62082302
137dendritic cell chemotaxis (GO:0002407)2.62062549
138myeloid leukocyte activation (GO:0002274)2.61700257
139negative regulation of type I interferon production (GO:0032480)2.61266593
140production of molecular mediator involved in inflammatory response (GO:0002532)2.61011824
141positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.60367695
142regulation of T cell receptor signaling pathway (GO:0050856)2.60202761
143positive regulation of macrophage differentiation (GO:0045651)2.60165950
144cellular response to interferon-gamma (GO:0071346)2.59985798
145regulation of interleukin-12 production (GO:0032655)2.59897316
146negative regulation of lymphocyte mediated immunity (GO:0002707)2.59728425
147microglial cell activation (GO:0001774)2.59396288
148T-helper cell differentiation (GO:0042093)2.58957231

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* IRF8_22096565_ChIP-ChIP_GC-B_Human6.82111594
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.32177749
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.20770655
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.78232336
5* IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.54870029
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.33820749
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.74928434
8E2F7_22180533_ChIP-Seq_HELA_Human3.65617318
9IRF8_27001747_Chip-Seq_BMDM_Mouse3.23681349
10* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.15616098
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.08913285
12EGR1_19374776_ChIP-ChIP_THP-1_Human3.07258693
13* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.04423247
14* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.92537409
15* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.87236437
16* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.84457563
17RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.71086104
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.58863775
19MYB_26560356_Chip-Seq_TH2_Human2.27133148
20Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.24628791
21SCL_19346495_ChIP-Seq_HPC-7_Human2.23293543
22RUNX_20019798_ChIP-Seq_JUKART_Human2.09738345
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.08790935
24SPI1_23547873_ChIP-Seq_NB4_Human2.05470974
25MYB_26560356_Chip-Seq_TH1_Human1.95576762
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.94835531
27STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.94265017
28* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87364890
29ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.87332667
30* MAF_26560356_Chip-Seq_TH1_Human1.85918129
31TP63_17297297_ChIP-ChIP_HaCaT_Human1.80645189
32ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79069874
33BRD4_27068464_Chip-Seq_AML-cells_Mouse1.76006288
34NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.74088765
35GATA1_22025678_ChIP-Seq_K562_Human1.65589978
36PU_27001747_Chip-Seq_BMDM_Mouse1.59974013
37RUNX1_22412390_ChIP-Seq_EML_Mouse1.59496962
38NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.58551475
39RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.58398755
40* VDR_24763502_ChIP-Seq_THP-1_Human1.57326708
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.57182832
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.55718381
43STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.43314197
44MYC_22102868_ChIP-Seq_BL_Human1.33917860
45* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32962144
46* UTX_26944678_Chip-Seq_JUKART_Human1.32599846
47* VDR_21846776_ChIP-Seq_THP-1_Human1.30962326
48NOTCH1_21737748_ChIP-Seq_TLL_Human1.30170318
49PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28677111
50GATA3_27048872_Chip-Seq_THYMUS_Human1.28411968
51CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27646069
52MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24286143
53GATA2_22383799_ChIP-Seq_G1ME_Mouse1.23219451
54VDR_24787735_ChIP-Seq_THP-1_Human1.19431263
55ELK1_19687146_ChIP-ChIP_HELA_Human1.18581894
56GATA3_26560356_Chip-Seq_TH2_Human1.17375550
57TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15905103
58PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15812130
59LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.15807480
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13607363
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.12489220
62MAF_26560356_Chip-Seq_TH2_Human1.09483734
63EGR1_23403033_ChIP-Seq_LIVER_Mouse1.07626214
64HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07393232
65GATA2_21666600_ChIP-Seq_HMVEC_Human1.06948147
66* SPI1_23127762_ChIP-Seq_K562_Human1.05063698
67EZH2_27294783_Chip-Seq_NPCs_Mouse1.04083736
68* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03832515
69PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02123924
70CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01814583
71NFE2_27457419_Chip-Seq_LIVER_Mouse1.01166196
72* GATA1_19941826_ChIP-Seq_K562_Human1.00792692
73SMRT_27268052_Chip-Seq_Bcells_Human0.99990431
74* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99866467
75ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99826476
76LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.99391442
77VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98829094
78* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98006173
79GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95752089
80SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95469110
81E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95177323
82TCF7_22412390_ChIP-Seq_EML_Mouse0.95043520
83VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.94707199
84SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.94036844
85FOXP3_21729870_ChIP-Seq_TREG_Human0.93734470
86GATA1_22383799_ChIP-Seq_G1ME_Mouse0.92694659
87GATA3_26560356_Chip-Seq_TH1_Human0.92467930
88TFEB_21752829_ChIP-Seq_HELA_Human0.92066663
89SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91732901
90SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.91231359
91SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.91231359
92* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.86207790
93CRX_20693478_ChIP-Seq_RETINA_Mouse0.85770355
94CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.85705916
95SALL1_21062744_ChIP-ChIP_HESCs_Human0.84853163
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.84465737
97SMAD_19615063_ChIP-ChIP_OVARY_Human0.84004588
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.83564072
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83250966
100OCT4_21477851_ChIP-Seq_ESCs_Mouse0.81882072
101GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80905274
102SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.77851869
103PU.1_20513432_ChIP-Seq_Bcells_Mouse0.76432183
104RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.76380967
105VDR_23849224_ChIP-Seq_CD4+_Human0.74475753
106* GATA1_19941827_ChIP-Seq_MEL_Mouse0.74389709
107CDX2_22108803_ChIP-Seq_LS180_Human0.74083922
108THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.73721984
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.72926174
110TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.72848376
111POU3F2_20337985_ChIP-ChIP_501MEL_Human0.72531879
112E2F4_17652178_ChIP-ChIP_JURKAT_Human0.72237972
113FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.71185618
114STAT6_21828071_ChIP-Seq_BEAS2B_Human0.70553110
115FOXO3_23340844_ChIP-Seq_DLD1_Human0.69998010
116KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.69607782
117NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.68923525
118ELK3_25401928_ChIP-Seq_HUVEC_Human0.68820878
119TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.68125062
120CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.67505297
121ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.65266661
122FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.64053462
123BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.62184452
124* GATA2_19941826_ChIP-Seq_K562_Human0.60560896

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.48210152
2MP0009785_altered_susceptibility_to3.55821496
3MP0002148_abnormal_hypersensitivity_rea3.33350883
4MP0005671_abnormal_response_to3.23224472
5MP0003436_decreased_susceptibility_to3.18137414
6MP0000685_abnormal_immune_system3.10767828
7MP0005000_abnormal_immune_tolerance2.96984651
8MP0003724_increased_susceptibility_to2.93286554
9MP0005387_immune_system_phenotype2.92584534
10MP0001790_abnormal_immune_system2.92584534
11MP0005025_abnormal_response_to2.74564851
12MP0001800_abnormal_humoral_immune2.66305108
13MP0002419_abnormal_innate_immunity2.58684336
14MP0002452_abnormal_antigen_presenting2.57938425
15MP0002723_abnormal_immune_serum2.50863582
16MP0003763_abnormal_thymus_physiology2.43755928
17MP0006082_CNS_inflammation2.41836999
18MP0001819_abnormal_immune_cell2.33565966
19MP0002420_abnormal_adaptive_immunity2.31231692
20MP0002006_tumorigenesis2.28791611
21MP0002166_altered_tumor_susceptibility2.24032718
22MP0009333_abnormal_splenocyte_physiolog2.07920116
23MP0002405_respiratory_system_inflammati2.05083469
24MP0001853_heart_inflammation1.99387995
25MP0002398_abnormal_bone_marrow1.96954223
26MP0010155_abnormal_intestine_physiology1.92890679
27MP0005464_abnormal_platelet_physiology1.89149148
28MP0000716_abnormal_immune_system1.86776285
29MP0004947_skin_inflammation1.75770331
30MP0001845_abnormal_inflammatory_respons1.75469119
31MP0003303_peritoneal_inflammation1.73886682
32MP0001348_abnormal_lacrimal_gland1.68528215
33MP0004510_myositis1.67221108
34MP0000689_abnormal_spleen_morphology1.65279241
35MP0002722_abnormal_immune_system1.59047287
36MP0001533_abnormal_skeleton_physiology1.58985782
37MP0009764_decreased_sensitivity_to1.58072077
38MP0005397_hematopoietic_system_phenotyp1.55874699
39MP0001545_abnormal_hematopoietic_system1.55874699
40MP0002429_abnormal_blood_cell1.53101389
41MP0003195_calcinosis1.51930196
42MP0005310_abnormal_salivary_gland1.49047293
43MP0008469_abnormal_protein_level1.47191764
44MP0000858_altered_metastatic_potential1.44403456
45MP0003448_altered_tumor_morphology1.43265147
46MP0002138_abnormal_hepatobiliary_system1.37540449
47MP0002396_abnormal_hematopoietic_system1.35771659
48MP0004808_abnormal_hematopoietic_stem1.31993717
49MP0004782_abnormal_surfactant_physiolog1.31385894
50MP0002009_preneoplasia1.29315314
51MP0000372_irregular_coat_pigmentation1.28867750
52MP0000490_abnormal_crypts_of1.28730149
53MP0002998_abnormal_bone_remodeling1.25325285
54MP0005075_abnormal_melanosome_morpholog1.24238587
55MP0002877_abnormal_melanocyte_morpholog1.23597752
56MP0000703_abnormal_thymus_morphology1.23431123
57MP0000569_abnormal_digit_pigmentation1.23378775
58MP0003191_abnormal_cellular_cholesterol1.22566580
59MP0001873_stomach_inflammation1.22320741
60MP0002933_joint_inflammation1.21614775
61MP0003186_abnormal_redox_activity1.17107486
62MP0009278_abnormal_bone_marrow1.16426599
63MP0003172_abnormal_lysosome_physiology1.13120707
64MP0000015_abnormal_ear_pigmentation1.11168967
65MP0005408_hypopigmentation1.10700003
66MP0000343_altered_response_to1.09395874
67MP0005058_abnormal_lysosome_morphology1.08707422
68MP0004381_abnormal_hair_follicle1.08113011
69MP0003300_gastrointestinal_ulcer1.06356367
70MP0003866_abnormal_defecation1.06082847
71MP0002277_abnormal_respiratory_mucosa1.06076986
72MP0005174_abnormal_tail_pigmentation1.02158620
73MP0000371_diluted_coat_color0.96007891
74MP0010307_abnormal_tumor_latency0.95863954
75MP0008004_abnormal_stomach_pH0.94738607
76MP0009763_increased_sensitivity_to0.94420458
77MP0009840_abnormal_foam_cell0.94082923
78MP0002132_abnormal_respiratory_system0.93538657
79MP0000465_gastrointestinal_hemorrhage0.91784621
80MP0009765_abnormal_xenobiotic_induced0.91358579
81MP0006054_spinal_hemorrhage0.90209631
82MP0008057_abnormal_DNA_replication0.90011784
83MP0002332_abnormal_exercise_endurance0.87011654
84MP0001919_abnormal_reproductive_system0.86509582
85MP0004883_abnormal_blood_vessel0.83444261
86MP0010352_gastrointestinal_tract_polyps0.81915455
87MP0003806_abnormal_nucleotide_metabolis0.81442560
88MP0002163_abnormal_gland_morphology0.80360153
89MP0002693_abnormal_pancreas_physiology0.80271051
90MP0005390_skeleton_phenotype0.79122847
91MP0003786_premature_aging0.78347360
92MP0003646_muscle_fatigue0.78085105
93MP0002019_abnormal_tumor_incidence0.77992544
94MP0005451_abnormal_body_composition0.76171766
95MP0003566_abnormal_cell_adhesion0.75454783
96MP0003453_abnormal_keratinocyte_physiol0.75278633
97MP0005023_abnormal_wound_healing0.75203495
98MP0002254_reproductive_system_inflammat0.74129186
99MP0005389_reproductive_system_phenotype0.71531792
100MP0001851_eye_inflammation0.69544436
101MP0005647_abnormal_sex_gland0.69531968
102MP0005164_abnormal_response_to0.68779562
103MP0005076_abnormal_cell_differentiation0.68749223
104MP0008007_abnormal_cellular_replicative0.68651911
105MP0003075_altered_response_to0.67667658
106MP0005167_abnormal_blood-brain_barrier0.66526252
107MP0000249_abnormal_blood_vessel0.65469344
108MP0005166_decreased_susceptibility_to0.65192552
109MP0004264_abnormal_extraembryonic_tissu0.64154248
110MP0001663_abnormal_digestive_system0.63608391
111MP0003795_abnormal_bone_structure0.62899005
112MP0003828_pulmonary_edema0.62732150
113MP0003091_abnormal_cell_migration0.62323171
114MP0002136_abnormal_kidney_physiology0.62017444
115MP0009115_abnormal_fat_cell0.61956749
116MP0003045_fibrosis0.60857884
117MP0003656_abnormal_erythrocyte_physiolo0.60491637
118MP0001542_abnormal_bone_strength0.60103163
119MP0000767_abnormal_smooth_muscle0.58004099
120MP0001881_abnormal_mammary_gland0.57878345
121MP0004185_abnormal_adipocyte_glucose0.57448228
122MP0000609_abnormal_liver_physiology0.55567402
123MP0003252_abnormal_bile_duct0.55535913
124MP0008873_increased_physiological_sensi0.54922729
125MP0008877_abnormal_DNA_methylation0.54664287

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.27880203
2Recurrent abscess formation (HP:0002722)5.21089923
3Recurrent bacterial skin infections (HP:0005406)4.78566132
4Autoimmune thrombocytopenia (HP:0001973)4.73533784
5Elevated erythrocyte sedimentation rate (HP:0003565)4.64903149
6Mediastinal lymphadenopathy (HP:0100721)4.35494919
7Myositis (HP:0100614)4.27333679
8Increased IgM level (HP:0003496)3.94127585
9Recurrent fungal infections (HP:0002841)3.89191404
10Orchitis (HP:0100796)3.88872687
11Optic neuritis (HP:0100653)3.83032094
12Retrobulbar optic neuritis (HP:0100654)3.83032094
13Vasculitis (HP:0002633)3.75641747
14Recurrent viral infections (HP:0004429)3.73697538
15Recurrent gram-negative bacterial infections (HP:0005420)3.67178051
16Abnormality of T cell number (HP:0011839)3.48633411
17Hematochezia (HP:0002573)3.38465421
18Abnormality of macrophages (HP:0004311)3.33256898
19Stomatitis (HP:0010280)3.29895895
20Recurrent skin infections (HP:0001581)3.26822042
21Chronic otitis media (HP:0000389)3.25903292
22Basal ganglia calcification (HP:0002135)3.23645908
23Meningitis (HP:0001287)3.20911505
24T lymphocytopenia (HP:0005403)3.19417651
25Hypergammaglobulinemia (HP:0010702)3.06717860
26Pustule (HP:0200039)2.99313882
27Chronic mucocutaneous candidiasis (HP:0002728)2.98534155
28Recurrent cutaneous fungal infections (HP:0011370)2.98534155
29Petechiae (HP:0000967)2.98136708
30Abnormality of T cells (HP:0002843)2.97933219
31Periodontitis (HP:0000704)2.95116151
32Eosinophilia (HP:0001880)2.93665107
33Pulmonary infiltrates (HP:0002113)2.91254256
34Autoimmune hemolytic anemia (HP:0001890)2.89944952
35Obstructive lung disease (HP:0006536)2.89678110
36Chronic obstructive pulmonary disease (HP:0006510)2.89678110
37Abnormal delayed hypersensitivity skin test (HP:0002963)2.83867237
38Gingivitis (HP:0000230)2.82972163
39Abnormality of T cell physiology (HP:0011840)2.80891343
40Cellulitis (HP:0100658)2.80256473
41Recurrent bronchitis (HP:0002837)2.76612389
42Leukocytosis (HP:0001974)2.75715075
43Granulocytopenia (HP:0001913)2.72166249
44Gingival bleeding (HP:0000225)2.64000703
45Poor head control (HP:0002421)2.62938729
46Combined immunodeficiency (HP:0005387)2.61871883
47Keratoconjunctivitis sicca (HP:0001097)2.61734234
48Vacuolated lymphocytes (HP:0001922)2.60818702
49Thrombocytosis (HP:0001894)2.60040510
50Severe combined immunodeficiency (HP:0004430)2.59630688
51Arterial thrombosis (HP:0004420)2.57521841
52IgA deficiency (HP:0002720)2.56258666
53Gastrointestinal infarctions (HP:0005244)2.55038418
54Hemoptysis (HP:0002105)2.54441607
55Abnormality of eosinophils (HP:0001879)2.52812967
56Abnormality of the prostate (HP:0008775)2.52733887
57Prostate neoplasm (HP:0100787)2.49208836
58IgG deficiency (HP:0004315)2.48464373
59Systemic lupus erythematosus (HP:0002725)2.47897580
60IgM deficiency (HP:0002850)2.45160198
61Gangrene (HP:0100758)2.44513527
62Agammaglobulinemia (HP:0004432)2.44235231
63Interstitial pulmonary disease (HP:0006530)2.39202390
64Keratoconjunctivitis (HP:0001096)2.38175013
65Abnormality of the pleura (HP:0002103)2.37110124
66Joint swelling (HP:0001386)2.36493640
67Thyroiditis (HP:0100646)2.34987803
68Epistaxis (HP:0000421)2.33001814
69Recurrent pneumonia (HP:0006532)2.32945492
70Panhypogammaglobulinemia (HP:0003139)2.31357468
71Osteolytic defects of the phalanges of the hand (HP:0009771)2.30261223
72Osteolytic defects of the hand bones (HP:0009699)2.30261223
73Pulmonary embolism (HP:0002204)2.29366306
74Vertebral compression fractures (HP:0002953)2.29110704
75Encephalitis (HP:0002383)2.28994402
76Abnormality of cells of the lymphoid lineage (HP:0012140)2.28950285
77Alveolar cell carcinoma (HP:0006519)2.28474410
78Chest pain (HP:0100749)2.28437627
79Osteomyelitis (HP:0002754)2.27818291
80Abnormality of B cell number (HP:0010975)2.25695297
81B lymphocytopenia (HP:0010976)2.25695297
82Prolonged bleeding time (HP:0003010)2.24647482
83Lymphopenia (HP:0001888)2.23148514
84Abnormality of the fingertips (HP:0001211)2.22789168
85Spinal cord lesions (HP:0100561)2.22192377
86Syringomyelia (HP:0003396)2.22192377
87Nasal polyposis (HP:0100582)2.21465893
88Stomach cancer (HP:0012126)2.21095881
89Spontaneous hematomas (HP:0007420)2.19201902
90Recurrent lower respiratory tract infections (HP:0002783)2.17229286
91Lymphoma (HP:0002665)2.16701039
92Hypochromic anemia (HP:0001931)2.16698378
93Neoplasm of the tracheobronchial system (HP:0100552)2.16532491
94Myocardial infarction (HP:0001658)2.15043740
95Chronic diarrhea (HP:0002028)2.14818558
96Porencephaly (HP:0002132)2.14451122
97Tetraparesis (HP:0002273)2.12103068
98Anorexia (HP:0002039)2.11681863
99Papilloma (HP:0012740)2.10363595
100Verrucae (HP:0200043)2.10363595
101Keratitis (HP:0000491)2.09232304
102Urticaria (HP:0001025)2.08674466
103Polyneuropathy (HP:0001271)2.08164066
104Skin ulcer (HP:0200042)2.06576123
105Cheilitis (HP:0100825)2.04757424
106Purpura (HP:0000979)2.03904881
107Amaurosis fugax (HP:0100576)2.03160344
108Reduced antithrombin III activity (HP:0001976)2.01981722
109Inflammation of the large intestine (HP:0002037)1.98237198
110Subacute progressive viral hepatitis (HP:0006572)1.97428831
111Abnormality of the nasal mucosa (HP:0000433)1.96942031
112Microcytic anemia (HP:0001935)1.96218914
113Increased IgE level (HP:0003212)1.94322211
114Hypochromic microcytic anemia (HP:0004840)1.93193297
115Albinism (HP:0001022)1.93074706
116Arthralgia (HP:0002829)1.91249952
117Joint hemorrhage (HP:0005261)1.91082680
118Viral hepatitis (HP:0006562)1.87793270
119Glomerulopathy (HP:0100820)1.81963614
120Prominent nose (HP:0000448)1.77787782
121Pulmonary fibrosis (HP:0002206)1.76549431
122Conjunctival hamartoma (HP:0100780)1.76328439
123Abnormality of male internal genitalia (HP:0000022)1.72597299
124Thrombophlebitis (HP:0004418)1.71118055
125Fair hair (HP:0002286)1.70870285
126Episodic fever (HP:0001954)1.68622060
127Vertigo (HP:0002321)1.67861986
128Mucosal telangiectasiae (HP:0100579)1.67205265

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.86591763
2TXK3.42995517
3MAP4K13.16909272
4JAK32.97950505
5TYK22.91183771
6IKBKE2.88620790
7TBK12.86742301
8IRAK42.86333718
9IRAK32.64022913
10IKBKB2.61311967
11BLK2.18176432
12PIM22.13240857
13PBK1.99088301
14JAK11.89935894
15TEC1.89733386
16CHUK1.89706061
17PIM11.89397144
18ZAP701.84757476
19MST41.82145455
20FES1.80015488
21KIT1.68502958
22RIPK41.59889101
23STK101.52447072
24BTK1.51692503
25BMPR21.49162484
26SYK1.48093649
27NME21.43307691
28FGFR41.40582193
29STK41.39221178
30NEK91.38772540
31TAOK31.33474259
32FGFR31.32186153
33CSK1.31041302
34TRPM71.28863837
35NLK1.26497636
36ITK1.25249564
37LCK1.19742895
38MAP4K21.13262124
39ZAK1.13215060
40ERN11.11943007
41PRPF4B1.10933976
42EIF2AK21.10725666
43YES11.07464674
44GRK71.06137604
45LYN1.03120420
46MELK1.01778680
47RPS6KA41.01262811
48VRK11.01207814
49TRIM280.99754810
50SIK30.99689364
51JAK20.99068118
52TGFBR20.98442406
53MAP3K130.98435335
54BMPR1B0.94730132
55MARK30.94484403
56MAP2K30.92300103
57CAMKK20.89202489
58CLK10.87262935
59* HCK0.86512039
60TLK10.83490354
61CSF1R0.81906616
62BRD40.81394482
63ERBB30.80623179
64BMX0.78979191
65NUAK10.78952948
66TAF10.76621255
67TNK20.74190061
68CDK120.73149186
69MAP3K30.72940036
70EPHA30.72200968
71EIF2AK10.69294009
72CDK60.67353981
73STK240.66570250
74PRKCQ0.63565259
75IRAK10.62551633
76EPHB10.61769826
77MAP3K10.60825704
78MKNK20.60132287
79EIF2AK30.59403722
80GRK60.59033443
81STK30.58701537
82ABL10.57890945
83ABL20.57031617
84MAP2K60.56627316
85FLT30.52892247
86PRKCD0.51343704
87ACVR1B0.51288502
88LRRK20.51269601
89MST1R0.51128905
90MATK0.50975248
91FGR0.50953093
92PTK2B0.50488235
93PIK3CG0.49849181
94RIPK10.49709596
95MAP3K50.48592670
96RPS6KA60.48092175
97TNIK0.47160120
98TGFBR10.47019842
99MAPKAPK20.46836457
100CDK40.46612053
101KDR0.44479560
102MAP3K110.44242810
103PIK3CA0.44159342
104GRK10.41322557
105RPS6KA50.40128796
106AKT30.39383873
107PASK0.38901759
108PLK40.38634842
109SMG10.38314398
110PRKG20.37018171
111PDK10.36392995
112RPS6KL10.35445858
113RPS6KC10.35445858
114GRK50.35267195
115HIPK20.34448797
116PLK30.34110988
117ATR0.32647626
118MAP3K100.31790655
119MAPK70.31698330
120FRK0.29522569
121MAPK30.29462367
122MAPK40.29193224
123MAP3K20.29166561
124TESK10.28683535
125IRAK20.27601235
126ADRBK10.27415854
127MAPKAPK30.27168147
128EGFR0.26285561
129RPS6KB20.25692853
130MAPK110.24462160
131ADRBK20.23542767
132IGF1R0.22785709
133TAOK20.22460578

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.27172851
2Allograft rejection_Homo sapiens_hsa053303.15487529
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.91937211
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.79342894
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.74276927
6Leishmaniasis_Homo sapiens_hsa051402.69001125
7Measles_Homo sapiens_hsa051622.60129733
8Primary immunodeficiency_Homo sapiens_hsa053402.51925354
9RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.45197570
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.39126523
11Toll-like receptor signaling pathway_Homo sapiens_hsa046202.35651475
12NOD-like receptor signaling pathway_Homo sapiens_hsa046212.07249187
13Herpes simplex infection_Homo sapiens_hsa051682.02373840
14Legionellosis_Homo sapiens_hsa051342.00758739
15Autoimmune thyroid disease_Homo sapiens_hsa053201.91771153
16Osteoclast differentiation_Homo sapiens_hsa043801.89729288
17Influenza A_Homo sapiens_hsa051641.88797779
18Staphylococcus aureus infection_Homo sapiens_hsa051501.84325870
19Type I diabetes mellitus_Homo sapiens_hsa049401.78683815
20Antigen processing and presentation_Homo sapiens_hsa046121.76471053
21Malaria_Homo sapiens_hsa051441.75894583
22Asthma_Homo sapiens_hsa053101.70195114
23TNF signaling pathway_Homo sapiens_hsa046681.68906715
24Hematopoietic cell lineage_Homo sapiens_hsa046401.66932860
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.66116157
26Pertussis_Homo sapiens_hsa051331.59216042
27Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.56288876
28Toxoplasmosis_Homo sapiens_hsa051451.52180338
29Rheumatoid arthritis_Homo sapiens_hsa053231.49100568
30Tuberculosis_Homo sapiens_hsa051521.46449335
31Apoptosis_Homo sapiens_hsa042101.45169168
32B cell receptor signaling pathway_Homo sapiens_hsa046621.39631434
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.38748342
34Viral myocarditis_Homo sapiens_hsa054161.26494559
35Hepatitis B_Homo sapiens_hsa051611.24986165
36T cell receptor signaling pathway_Homo sapiens_hsa046601.23649646
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.21589997
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21314100
39Salmonella infection_Homo sapiens_hsa051321.12768489
40Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.12656194
41Shigellosis_Homo sapiens_hsa051311.12569792
42Chemokine signaling pathway_Homo sapiens_hsa040621.10981960
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10502858
44African trypanosomiasis_Homo sapiens_hsa051431.10244982
45Hepatitis C_Homo sapiens_hsa051601.05219843
46Dorso-ventral axis formation_Homo sapiens_hsa043200.95311583
47Other glycan degradation_Homo sapiens_hsa005110.94655368
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.90504943
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90309618
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.88804778
51Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86135610
52Acute myeloid leukemia_Homo sapiens_hsa052210.84077774
53Epstein-Barr virus infection_Homo sapiens_hsa051690.82703058
54p53 signaling pathway_Homo sapiens_hsa041150.82477717
55Leukocyte transendothelial migration_Homo sapiens_hsa046700.81301818
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79896214
57DNA replication_Homo sapiens_hsa030300.78773053
58One carbon pool by folate_Homo sapiens_hsa006700.78407356
59Lysosome_Homo sapiens_hsa041420.74594149
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74404848
61Phagosome_Homo sapiens_hsa041450.73040968
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71970111
63Base excision repair_Homo sapiens_hsa034100.70810429
64Non-small cell lung cancer_Homo sapiens_hsa052230.70590634
65Proteasome_Homo sapiens_hsa030500.70313335
66Viral carcinogenesis_Homo sapiens_hsa052030.67474989
67Prolactin signaling pathway_Homo sapiens_hsa049170.66015351
68Small cell lung cancer_Homo sapiens_hsa052220.64776809
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61666515
70Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59153584
71Chronic myeloid leukemia_Homo sapiens_hsa052200.58083361
72HTLV-I infection_Homo sapiens_hsa051660.55147986
73Platelet activation_Homo sapiens_hsa046110.51129579
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50893036
75Basal transcription factors_Homo sapiens_hsa030220.50714636
76Insulin resistance_Homo sapiens_hsa049310.50679757
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50587326
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50133450
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.48139037
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.47263852
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45569818
82Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.45508313
83Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45452491
84Homologous recombination_Homo sapiens_hsa034400.45093425
85Mismatch repair_Homo sapiens_hsa034300.43488887
86Notch signaling pathway_Homo sapiens_hsa043300.43235918
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.42052662
88Regulation of autophagy_Homo sapiens_hsa041400.39800160
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36936627
90Sulfur metabolism_Homo sapiens_hsa009200.36403894
91Amoebiasis_Homo sapiens_hsa051460.36160402
92Complement and coagulation cascades_Homo sapiens_hsa046100.34509937
93Prostate cancer_Homo sapiens_hsa052150.33779359
94Pancreatic cancer_Homo sapiens_hsa052120.33666053
95MicroRNAs in cancer_Homo sapiens_hsa052060.33503708
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33381632
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33026435
98Systemic lupus erythematosus_Homo sapiens_hsa053220.32236918
99mTOR signaling pathway_Homo sapiens_hsa041500.31986626
100Caffeine metabolism_Homo sapiens_hsa002320.31713503
101Non-homologous end-joining_Homo sapiens_hsa034500.30859405
102Adipocytokine signaling pathway_Homo sapiens_hsa049200.30461385
103HIF-1 signaling pathway_Homo sapiens_hsa040660.30445064
104Type II diabetes mellitus_Homo sapiens_hsa049300.29713401
105VEGF signaling pathway_Homo sapiens_hsa043700.29467381
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.29356605
107Phosphatidylinositol signaling system_Homo sapiens_hsa040700.29343339
108Selenocompound metabolism_Homo sapiens_hsa004500.28148585
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.27017977
110FoxO signaling pathway_Homo sapiens_hsa040680.25605180
111Galactose metabolism_Homo sapiens_hsa000520.22930093
112MAPK signaling pathway_Homo sapiens_hsa040100.22812709
113RNA degradation_Homo sapiens_hsa030180.22809828
114Thyroid cancer_Homo sapiens_hsa052160.21870801
115Protein export_Homo sapiens_hsa030600.21458243
116Inositol phosphate metabolism_Homo sapiens_hsa005620.20961281
117ABC transporters_Homo sapiens_hsa020100.20676894
118Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19896455
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.19872883
120Pyrimidine metabolism_Homo sapiens_hsa002400.19793918
121Fanconi anemia pathway_Homo sapiens_hsa034600.19059215
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.17182174
123Linoleic acid metabolism_Homo sapiens_hsa005910.16411394
124Colorectal cancer_Homo sapiens_hsa052100.16218708

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