ZBTB9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule catabolic process (GO:0016998)5.25343519
2cell wall macromolecule metabolic process (GO:0044036)5.25343519
3establishment of integrated proviral latency (GO:0075713)4.89472608
4fusion of sperm to egg plasma membrane (GO:0007342)4.78153295
5mitotic metaphase plate congression (GO:0007080)4.49368303
6ribosomal small subunit assembly (GO:0000028)4.30561812
7establishment of viral latency (GO:0019043)4.05811106
8sperm-egg recognition (GO:0035036)4.05262746
9heterochromatin organization (GO:0070828)4.04724472
10multicellular organism reproduction (GO:0032504)3.81819780
11cell-cell recognition (GO:0009988)3.77156689
12L-serine metabolic process (GO:0006563)3.66588906
13peptidyl-arginine omega-N-methylation (GO:0035247)3.66030478
14metaphase plate congression (GO:0051310)3.62913347
15motile cilium assembly (GO:0044458)3.62221526
16nuclear pore complex assembly (GO:0051292)3.52555382
17acrosome assembly (GO:0001675)3.51455051
18binding of sperm to zona pellucida (GO:0007339)3.50638418
19regulation of mitochondrial translation (GO:0070129)3.47462366
20mitotic chromosome condensation (GO:0007076)3.45042126
21histone arginine methylation (GO:0034969)3.40641886
22cilium or flagellum-dependent cell motility (GO:0001539)3.38642244
23plasma membrane fusion (GO:0045026)3.38453998
24peptidyl-arginine N-methylation (GO:0035246)3.37583923
25peptidyl-arginine methylation (GO:0018216)3.37583923
26nuclear pore organization (GO:0006999)3.34300092
27DNA deamination (GO:0045006)3.33911570
28regulation of helicase activity (GO:0051095)3.33369911
29proteasome assembly (GO:0043248)3.33254392
30microtubule depolymerization (GO:0007019)3.31590400
31DNA strand elongation involved in DNA replication (GO:0006271)3.30501638
32DNA unwinding involved in DNA replication (GO:0006268)3.25894494
33DNA replication initiation (GO:0006270)3.24501580
34ribosome assembly (GO:0042255)3.20503844
35DNA strand elongation (GO:0022616)3.20461106
36mitotic sister chromatid segregation (GO:0000070)3.18734724
37ribosome biogenesis (GO:0042254)3.18650057
38base-excision repair (GO:0006284)3.16247234
39reproduction (GO:0000003)3.12957374
40mitotic nuclear envelope disassembly (GO:0007077)3.09320996
41maturation of SSU-rRNA (GO:0030490)3.07358507
42telomere maintenance via semi-conservative replication (GO:0032201)3.06298963
43positive regulation of gamma-delta T cell activation (GO:0046645)3.02844226
44proline biosynthetic process (GO:0006561)3.02499241
45regulation of translational fidelity (GO:0006450)3.01845177
46viral transcription (GO:0019083)3.01103452
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.01094516
48piRNA metabolic process (GO:0034587)2.99185053
49axonemal dynein complex assembly (GO:0070286)2.98599097
50translational termination (GO:0006415)2.98368084
51spliceosomal snRNP assembly (GO:0000387)2.97402207
52sister chromatid segregation (GO:0000819)2.95948137
53chromatin assembly (GO:0031497)2.95939229
54protein complex localization (GO:0031503)2.95553431
55pre-miRNA processing (GO:0031054)2.93722709
56negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.92663858
57antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.91170206
58antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.91170206
59IMP biosynthetic process (GO:0006188)2.89481877
60protein localization to chromosome, centromeric region (GO:0071459)2.89273738
61histone H2A acetylation (GO:0043968)2.88881176
62tRNA aminoacylation for protein translation (GO:0006418)2.87923951
63regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.87833762
64ATP-dependent chromatin remodeling (GO:0043044)2.87569675
65membrane disassembly (GO:0030397)2.87079094
66nuclear envelope disassembly (GO:0051081)2.87079094
67ribonucleoprotein complex biogenesis (GO:0022613)2.85847933
68telomere maintenance via recombination (GO:0000722)2.85625748
69intra-S DNA damage checkpoint (GO:0031573)2.84708355
70anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.83495931
71nucleobase biosynthetic process (GO:0046112)2.81314470
72somatic diversification of immune receptors via somatic mutation (GO:0002566)2.81245784
73somatic hypermutation of immunoglobulin genes (GO:0016446)2.81245784
74DNA ligation (GO:0006266)2.80544727
75viral mRNA export from host cell nucleus (GO:0046784)2.79948700
76negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78327596
77negative regulation of ligase activity (GO:0051352)2.78327596
78monoubiquitinated protein deubiquitination (GO:0035520)2.78119055
79formation of translation preinitiation complex (GO:0001731)2.77014500
80purine nucleobase biosynthetic process (GO:0009113)2.76787551
81chromatin assembly or disassembly (GO:0006333)2.76493635
82DNA replication-dependent nucleosome organization (GO:0034723)2.76193909
83DNA replication-dependent nucleosome assembly (GO:0006335)2.76193909
84amino acid activation (GO:0043038)2.75961299
85tRNA aminoacylation (GO:0043039)2.75961299
86translational elongation (GO:0006414)2.75306027
87chaperone-mediated protein transport (GO:0072321)2.73265411
88protein localization to kinetochore (GO:0034501)2.72085071
89establishment of protein localization to mitochondrial membrane (GO:0090151)2.71756019
90pore complex assembly (GO:0046931)2.71500013
91positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.71414463
92rRNA modification (GO:0000154)2.71135260
93rRNA transcription (GO:0009303)2.71029710
94establishment of chromosome localization (GO:0051303)2.70809839
95regulation of histone H3-K9 methylation (GO:0051570)2.70764741
96mitotic recombination (GO:0006312)2.70553073
97DNA geometric change (GO:0032392)2.68279409
98spliceosomal tri-snRNP complex assembly (GO:0000244)2.67970501
99DNA duplex unwinding (GO:0032508)2.67368815
100DNA topological change (GO:0006265)2.66786469
101protein-DNA complex disassembly (GO:0032986)2.65899755
102nucleosome disassembly (GO:0006337)2.65899755
103positive regulation of B cell differentiation (GO:0045579)2.65381997
104regulation of sister chromatid cohesion (GO:0007063)2.63607666
105translesion synthesis (GO:0019985)2.63464100
106negative regulation of chromosome segregation (GO:0051985)2.62462986
107cellular protein complex localization (GO:0034629)2.61859784
108protein localization to chromosome (GO:0034502)2.61479598
109translational initiation (GO:0006413)2.60891729
110protein maturation by protein folding (GO:0022417)2.60158494
111nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.59755376
112ribosomal small subunit biogenesis (GO:0042274)2.59673769
113sperm motility (GO:0030317)2.59656645
114histone exchange (GO:0043486)2.58844426
115folic acid-containing compound biosynthetic process (GO:0009396)2.58414415
116regulation of centriole replication (GO:0046599)2.57384247
117serine family amino acid biosynthetic process (GO:0009070)2.57231855
118negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.55696601
119negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.55696601
120negative regulation of mitotic sister chromatid segregation (GO:0033048)2.55696601
121negative regulation of mitotic sister chromatid separation (GO:2000816)2.55696601
122negative regulation of sister chromatid segregation (GO:0033046)2.55696601
123telomere maintenance via telomere lengthening (GO:0010833)2.55524901
124CENP-A containing nucleosome assembly (GO:0034080)2.55475022
125chromatin remodeling at centromere (GO:0031055)2.55465224
126DNA replication-independent nucleosome assembly (GO:0006336)2.54885628
127DNA replication-independent nucleosome organization (GO:0034724)2.54885628
128centriole assembly (GO:0098534)2.54640917
129positive regulation of viral transcription (GO:0050434)2.54097995
130mismatch repair (GO:0006298)2.54043980
131meiotic chromosome segregation (GO:0045132)2.52620771
132DNA replication checkpoint (GO:0000076)2.51750175
133telomere maintenance (GO:0000723)2.50705840
134ribosomal large subunit biogenesis (GO:0042273)2.50064489
135IMP metabolic process (GO:0046040)2.49801159
136telomere organization (GO:0032200)2.49736942
137pseudouridine synthesis (GO:0001522)2.49649955
138mitotic sister chromatid cohesion (GO:0007064)2.49600929
139snRNA metabolic process (GO:0016073)2.49563982
140deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.49329381
141SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.48792514
142mRNA cleavage (GO:0006379)2.48666215
143regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.48626950
144nucleotide-excision repair, DNA gap filling (GO:0006297)2.48257169
145postreplication repair (GO:0006301)2.47016342
146mast cell degranulation (GO:0043303)2.46361086
147mast cell activation involved in immune response (GO:0002279)2.46361086
148antigen processing and presentation of endogenous antigen (GO:0019883)2.46338118
149cellular protein complex disassembly (GO:0043624)2.45280852
150snRNA processing (GO:0016180)2.44923375
151spermatid development (GO:0007286)2.44919485
152spermatid nucleus differentiation (GO:0007289)2.43601303
153rRNA processing (GO:0006364)2.43252807
154rRNA metabolic process (GO:0016072)2.41257512
155histone mRNA catabolic process (GO:0071044)2.40229109
156mast cell activation (GO:0045576)2.39900850
157regulation of gamma-delta T cell differentiation (GO:0045586)2.39260901
158centriole replication (GO:0007099)2.38758443

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.43794703
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.50128328
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.14722252
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.02129036
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.01005540
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.81902075
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.73503437
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.62655536
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.52368597
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.45895985
11* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.31182532
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.28655336
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.20880008
14IRF8_22096565_ChIP-ChIP_GC-B_Human2.20156416
15IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19820546
16MYC_22102868_ChIP-Seq_BL_Human2.19047594
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.17773728
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.17469801
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.16835354
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.16370952
21* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.11101087
22VDR_23849224_ChIP-Seq_CD4+_Human2.09746598
23* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.08845280
24* NOTCH1_21737748_ChIP-Seq_TLL_Human2.07259812
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.06260119
26MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06248615
27* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.00312210
28* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.99817825
29FOXP3_21729870_ChIP-Seq_TREG_Human1.93755806
30ETS1_20019798_ChIP-Seq_JURKAT_Human1.87248091
31XRN2_22483619_ChIP-Seq_HELA_Human1.86972875
32SCL_19346495_ChIP-Seq_HPC-7_Human1.84968875
33MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.80123332
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.79148661
35DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.78036440
36* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77700824
37ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.76733863
38CIITA_25753668_ChIP-Seq_RAJI_Human1.76031915
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.75937247
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.74145773
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.73068000
42* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.71597022
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.71068618
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70656255
45POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.65873276
46* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.62572808
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.62556824
48ZNF263_19887448_ChIP-Seq_K562_Human1.61766402
49* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.60354982
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.56338777
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.55938779
52MYB_26560356_Chip-Seq_TH2_Human1.54100230
53GABP_19822575_ChIP-Seq_HepG2_Human1.53449440
54KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.52600457
55SOX2_18555785_ChIP-Seq_MESCs_Mouse1.52576948
56CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.52234474
57DCP1A_22483619_ChIP-Seq_HELA_Human1.52069485
58SPI1_23547873_ChIP-Seq_NB4_Human1.51051020
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50726643
60* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.50326615
61STAT4_19710469_ChIP-ChIP_TH1__Mouse1.48590275
62FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.43616568
63VDR_21846776_ChIP-Seq_THP-1_Human1.40476162
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.39136279
65* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.38651853
66TTF2_22483619_ChIP-Seq_HELA_Human1.36969713
67MYB_26560356_Chip-Seq_TH1_Human1.35401925
68HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35094971
69RBPJ_22232070_ChIP-Seq_NCS_Mouse1.34721987
70MYB_21317192_ChIP-Seq_ERMYB_Mouse1.33439906
71ELK1_19687146_ChIP-ChIP_HELA_Human1.32669916
72* RUNX1_22412390_ChIP-Seq_EML_Mouse1.32626125
73IRF8_21731497_ChIP-ChIP_J774_Mouse1.32608188
74PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.31216770
75* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.30621415
76STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.29298247
77NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.28020842
78AR_21909140_ChIP-Seq_LNCAP_Human1.26178191
79CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.24455657
80ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.24015345
81YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23634813
82KDM5A_27292631_Chip-Seq_BREAST_Human1.23361114
83KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.20627125
84CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.20380326
85SRF_21415370_ChIP-Seq_HL-1_Mouse1.20126655
86E2F1_18555785_ChIP-Seq_MESCs_Mouse1.19642179
87DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.19252269
88CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.17539984
89POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16940495
90POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.15973822
91NANOG_21062744_ChIP-ChIP_HESCs_Human1.15934141
92MAF_26560356_Chip-Seq_TH1_Human1.15830203
93FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.15741671
94NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.15716161
95UTX_26944678_Chip-Seq_JUKART_Human1.15444006
96STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.14057019
97SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.12486092
98IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.12180713
99ZFX_18555785_ChIP-Seq_MESCs_Mouse1.10634182
100THAP11_20581084_ChIP-Seq_MESCs_Mouse1.10526851
101MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.10504768
102PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10162833
103E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09995194
104ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09184097
105* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09150646
106YY1_21170310_ChIP-Seq_MESCs_Mouse1.08594205
107* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.04893254
108GATA2_22383799_ChIP-Seq_G1ME_Mouse1.04299998
109KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03900893
110BRD4_27068464_Chip-Seq_AML-cells_Mouse1.03325589
111TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02220409
112SOX2_16153702_ChIP-ChIP_HESCs_Human1.01657079
113MYC_18940864_ChIP-ChIP_HL60_Human1.00129643
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.00037800
115CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.99729309
116NANOG_16153702_ChIP-ChIP_HESCs_Human0.98595188
117GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98593865
118NANOG_18555785_ChIP-Seq_MESCs_Mouse0.98277313
119* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.98263458
120* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.97824585
121FOXP1_21924763_ChIP-Seq_HESCs_Human0.97631423
122TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97491546
123TFEB_21752829_ChIP-Seq_HELA_Human0.97416310
124SOX2_18692474_ChIP-Seq_MEFs_Mouse0.97004687
125TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96153160
126FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.95205255
127CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94074137
128SOX17_20123909_ChIP-Seq_XEN_Mouse0.94036355
129TP63_19390658_ChIP-ChIP_HaCaT_Human0.93898056
130VDR_24763502_ChIP-Seq_THP-1_Human0.92564951
131IRF8_27001747_Chip-Seq_BMDM_Mouse0.91349954
132OCT4_18692474_ChIP-Seq_MEFs_Mouse0.90976346
133CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.90789945
134TCF7_22412390_ChIP-Seq_EML_Mouse0.89761500
135SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.88812026
136KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.87625644
137KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.87625644
138KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.87625644

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.53936759
2MP0008057_abnormal_DNA_replication3.50405620
3MP0002396_abnormal_hematopoietic_system3.27982935
4MP0003693_abnormal_embryo_hatching3.23883907
5MP0003111_abnormal_nucleus_morphology3.11763017
6MP0008058_abnormal_DNA_repair3.02878219
7MP0005410_abnormal_fertilization2.90462212
8MP0003763_abnormal_thymus_physiology2.86870442
9MP0003077_abnormal_cell_cycle2.77953848
10MP0008007_abnormal_cellular_replicative2.68145014
11MP0001835_abnormal_antigen_presentation2.66940260
12MP0010030_abnormal_orbit_morphology2.65069787
13MP0008877_abnormal_DNA_methylation2.64987070
14MP0004808_abnormal_hematopoietic_stem2.51417369
15MP0000537_abnormal_urethra_morphology2.44434706
16MP0000685_abnormal_immune_system2.38495275
17MP0004957_abnormal_blastocyst_morpholog2.28976230
18MP0002398_abnormal_bone_marrow2.23397920
19MP0001800_abnormal_humoral_immune2.13794404
20MP0002132_abnormal_respiratory_system2.12764315
21MP0005671_abnormal_response_to2.12431294
22MP0003890_abnormal_embryonic-extraembry2.06727470
23MP0001545_abnormal_hematopoietic_system2.04581096
24MP0005397_hematopoietic_system_phenotyp2.04581096
25MP0001293_anophthalmia2.03108161
26MP0003315_abnormal_perineum_morphology1.98714443
27MP0009785_altered_susceptibility_to1.95098247
28MP0009672_abnormal_birth_weight1.94437944
29MP0010352_gastrointestinal_tract_polyps1.90546487
30MP0002420_abnormal_adaptive_immunity1.89878309
31MP0001790_abnormal_immune_system1.89551816
32MP0005387_immune_system_phenotype1.89551816
33MP0002452_abnormal_antigen_presenting1.89425551
34MP0008789_abnormal_olfactory_epithelium1.87814785
35MP0000703_abnormal_thymus_morphology1.87677726
36MP0001819_abnormal_immune_cell1.87603436
37MP0000490_abnormal_crypts_of1.87459433
38MP0002723_abnormal_immune_serum1.85063434
39MP0005394_taste/olfaction_phenotype1.84650152
40MP0005499_abnormal_olfactory_system1.84650152
41MP0010307_abnormal_tumor_latency1.84584577
42MP0002722_abnormal_immune_system1.84426561
43MP0000689_abnormal_spleen_morphology1.83879757
44MP0005174_abnormal_tail_pigmentation1.80027967
45MP0000716_abnormal_immune_system1.75849952
46MP0009333_abnormal_splenocyte_physiolog1.71242094
47MP0001929_abnormal_gametogenesis1.70781454
48MP0003436_decreased_susceptibility_to1.67025999
49MP0002405_respiratory_system_inflammati1.64063424
50MP0002429_abnormal_blood_cell1.63270108
51MP0005000_abnormal_immune_tolerance1.62143120
52MP0002166_altered_tumor_susceptibility1.61820076
53MP0005025_abnormal_response_to1.61788709
54MP0002085_abnormal_embryonic_tissue1.61547544
55MP0003941_abnormal_skin_development1.59959063
56MP0005464_abnormal_platelet_physiology1.59773765
57MP0002697_abnormal_eye_size1.58792990
58MP0002084_abnormal_developmental_patter1.56707340
59MP0000566_synostosis1.53896104
60MP0000049_abnormal_middle_ear1.48980083
61MP0002019_abnormal_tumor_incidence1.48324170
62MP0003937_abnormal_limbs/digits/tail_de1.46865605
63MP0002148_abnormal_hypersensitivity_rea1.46700378
64MP0002092_abnormal_eye_morphology1.45899033
65MP0003718_maternal_effect1.45390668
66MP0008995_early_reproductive_senescence1.40664943
67MP0000350_abnormal_cell_proliferation1.39522426
68MP0002111_abnormal_tail_morphology1.39288172
69MP0002210_abnormal_sex_determination1.39053635
70MP0003698_abnormal_male_reproductive1.38205020
71MP0000465_gastrointestinal_hemorrhage1.37030893
72MP0002419_abnormal_innate_immunity1.36225805
73MP0003786_premature_aging1.36093916
74MP0001286_abnormal_eye_development1.36033817
75MP0005075_abnormal_melanosome_morpholog1.34863593
76MP0010155_abnormal_intestine_physiology1.34810684
77MP0004947_skin_inflammation1.34302200
78MP0003942_abnormal_urinary_system1.33813788
79MP0001727_abnormal_embryo_implantation1.33644012
80MP0003119_abnormal_digestive_system1.33445445
81MP0004233_abnormal_muscle_weight1.32959623
82MP0009053_abnormal_anal_canal1.31257661
83MP0002233_abnormal_nose_morphology1.31158248
84MP0002006_tumorigenesis1.30968961
85MP0001529_abnormal_vocalization1.30564333
86MP0001346_abnormal_lacrimal_gland1.27836268
87MP0000858_altered_metastatic_potential1.25813747
88MP0002254_reproductive_system_inflammat1.25046372
89MP0002653_abnormal_ependyma_morphology1.23568327
90MP0009379_abnormal_foot_pigmentation1.22720727
91MP0000313_abnormal_cell_death1.22708326
92MP0006035_abnormal_mitochondrial_morpho1.22374841
93MP0004197_abnormal_fetal_growth/weight/1.20847074
94MP0000015_abnormal_ear_pigmentation1.20759877
95MP0003123_paternal_imprinting1.20158387
96MP0002095_abnormal_skin_pigmentation1.18378739
97MP0000579_abnormal_nail_morphology1.18295618
98MP0001145_abnormal_male_reproductive1.17568362
99MP0006054_spinal_hemorrhage1.16385621
100MP0001873_stomach_inflammation1.15398295
101MP0003122_maternal_imprinting1.15095291
102MP0003755_abnormal_palate_morphology1.13087311
103MP0009703_decreased_birth_body1.11407202
104MP0001730_embryonic_growth_arrest1.09813970
105MP0009278_abnormal_bone_marrow1.09671133
106MP0001849_ear_inflammation1.09435480
107MP0000762_abnormal_tongue_morphology1.08213591
108MP0001845_abnormal_inflammatory_respons1.06840585
109MP0004133_heterotaxia1.05924907
110MP0002098_abnormal_vibrissa_morphology1.05174433
111MP0001340_abnormal_eyelid_morphology1.04660900
112MP0000653_abnormal_sex_gland1.02206519
113MP0003861_abnormal_nervous_system1.01688162
114MP0000428_abnormal_craniofacial_morphol1.01532849
115MP0005257_abnormal_intraocular_pressure1.01525099
116MP0009697_abnormal_copulation1.01148695
117MP0008260_abnormal_autophagy1.00677070
118MP0003283_abnormal_digestive_organ1.00331863
119MP0001986_abnormal_taste_sensitivity0.98899055
120MP0001853_heart_inflammation0.96580097
121MP0003300_gastrointestinal_ulcer0.96537894
122MP0008932_abnormal_embryonic_tissue0.96409458
123MP0003567_abnormal_fetal_cardiomyocyte0.95890789
124MP0002938_white_spotting0.95822545
125MP0002102_abnormal_ear_morphology0.95657947
126MP0006082_CNS_inflammation0.95482643
127MP0005501_abnormal_skin_physiology0.94709890
128MP0003186_abnormal_redox_activity0.92750495
129MP0004264_abnormal_extraembryonic_tissu0.92363631
130MP0002796_impaired_skin_barrier0.90802623
131MP0003385_abnormal_body_wall0.89358545
132MP0002282_abnormal_trachea_morphology0.89120878
133MP0003115_abnormal_respiratory_system0.87884169
134MP0001697_abnormal_embryo_size0.86958969
135MP0002080_prenatal_lethality0.86914370
136MP0003866_abnormal_defecation0.86725503
137MP0003943_abnormal_hepatobiliary_system0.85410062
138MP0003935_abnormal_craniofacial_develop0.82937228
139MP0002116_abnormal_craniofacial_bone0.82389449
140MP0005409_darkened_coat_color0.82284571
141MP0005380_embryogenesis_phenotype0.81291315
142MP0001672_abnormal_embryogenesis/_devel0.81291315
143MP0002161_abnormal_fertility/fecundity0.79931044
144MP0002075_abnormal_coat/hair_pigmentati0.79432052
145MP0003136_yellow_coat_color0.78930677
146MP0000432_abnormal_head_morphology0.78693168
147MP0005076_abnormal_cell_differentiation0.78667950
148MP0002249_abnormal_larynx_morphology0.78330539
149MP0005391_vision/eye_phenotype0.76014124
150MP0001119_abnormal_female_reproductive0.74775359
151MP0002751_abnormal_autonomic_nervous0.74595424
152MP0000462_abnormal_digestive_system0.74031994
153MP0003121_genomic_imprinting0.73758712
154MP0003936_abnormal_reproductive_system0.73252064
155MP0002163_abnormal_gland_morphology0.72224303
156MP0003984_embryonic_growth_retardation0.71910378
157MP0002086_abnormal_extraembryonic_tissu0.71586369
158MP0005384_cellular_phenotype0.71309140
159MP0002088_abnormal_embryonic_growth/wei0.69749073
160MP0003303_peritoneal_inflammation0.69126216
161MP0006292_abnormal_olfactory_placode0.67333835
162MP0000371_diluted_coat_color0.65610315
163MP0000477_abnormal_intestine_morphology0.63874964
164MP0000358_abnormal_cell_content/0.62287189
165MP0001186_pigmentation_phenotype0.61471672
166MP0008469_abnormal_protein_level0.60917127
167MP0002160_abnormal_reproductive_system0.60877026
168MP0002877_abnormal_melanocyte_morpholog0.59446686

Predicted human phenotypes

RankGene SetZ-score
1Chronic otitis media (HP:0000389)4.93122883
2Nasal polyposis (HP:0100582)4.53844838
3Aplasia/Hypoplasia of the sacrum (HP:0008517)4.08965706
4Absent/shortened dynein arms (HP:0200106)3.87393439
5Dynein arm defect of respiratory motile cilia (HP:0012255)3.87393439
6Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.82312190
7Reticulocytopenia (HP:0001896)3.68661575
8Abnormality of the nasal mucosa (HP:0000433)3.65719788
9High anterior hairline (HP:0009890)3.46879253
10Thrombocytosis (HP:0001894)3.35622254
11Aplastic anemia (HP:0001915)3.23975031
12Recurrent bronchitis (HP:0002837)3.15184367
13Abnormal respiratory motile cilium morphology (HP:0005938)3.10045579
14Abnormal respiratory epithelium morphology (HP:0012253)3.10045579
15Recurrent viral infections (HP:0004429)3.04456457
16Petechiae (HP:0000967)3.04065833
17Panhypogammaglobulinemia (HP:0003139)3.00282504
18Bronchitis (HP:0012387)2.93423353
19IgM deficiency (HP:0002850)2.90254359
20Chronic sinusitis (HP:0011109)2.83562272
21Agnosia (HP:0010524)2.75502970
22Myelodysplasia (HP:0002863)2.72651077
23Chromsome breakage (HP:0040012)2.71797742
24Bronchiectasis (HP:0002110)2.71608064
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.68900276
26Abnormal number of erythroid precursors (HP:0012131)2.68021715
27Amaurosis fugax (HP:0100576)2.67756041
28Abnormality of cells of the erythroid lineage (HP:0012130)2.67494465
29Chronic bronchitis (HP:0004469)2.60781831
30Cortical dysplasia (HP:0002539)2.55698891
31Colon cancer (HP:0003003)2.53963327
32Recurrent fungal infections (HP:0002841)2.50086287
33Rhinitis (HP:0012384)2.48918376
34Birth length less than 3rd percentile (HP:0003561)2.47958227
35Shoulder girdle muscle weakness (HP:0003547)2.44412674
36Recurrent sinusitis (HP:0011108)2.43967153
37Basal cell carcinoma (HP:0002671)2.43381538
38Broad distal phalanx of finger (HP:0009836)2.41028955
39Abnormal respiratory motile cilium physiology (HP:0012261)2.40087099
40Multiple enchondromatosis (HP:0005701)2.40064282
41Microvesicular hepatic steatosis (HP:0001414)2.37748211
42Down-sloping shoulders (HP:0200021)2.34840717
43T lymphocytopenia (HP:0005403)2.34832201
44Hypoplastic pelvis (HP:0008839)2.34547766
45Recurrent abscess formation (HP:0002722)2.34510101
46Proximal placement of thumb (HP:0009623)2.34270731
47Lymphoma (HP:0002665)2.33304629
48Abnormal spermatogenesis (HP:0008669)2.32362903
49Hyperacusis (HP:0010780)2.31460654
50Pallor (HP:0000980)2.31158519
51Selective tooth agenesis (HP:0001592)2.30870180
52Abnormality of chromosome stability (HP:0003220)2.30659668
53Progressive muscle weakness (HP:0003323)2.28685654
54Breast hypoplasia (HP:0003187)2.27518390
55Abnormality of T cells (HP:0002843)2.26382358
56Abnormal number of incisors (HP:0011064)2.26006885
57Cutaneous melanoma (HP:0012056)2.25952351
5811 pairs of ribs (HP:0000878)2.25571705
59Abnormality of B cell number (HP:0010975)2.25350532
60B lymphocytopenia (HP:0010976)2.25350532
61Horseshoe kidney (HP:0000085)2.25233115
62Abnormality of the labia minora (HP:0012880)2.25043152
63Abnormality of T cell number (HP:0011839)2.24813356
64Missing ribs (HP:0000921)2.23656506
65Deviation of the thumb (HP:0009603)2.23583329
66IgG deficiency (HP:0004315)2.23542499
67Myelomeningocele (HP:0002475)2.23461733
68Abnormality of the preputium (HP:0100587)2.23416872
69Abnormality of the umbilical cord (HP:0010881)2.21155539
70Hemivertebrae (HP:0002937)2.19779316
71Prolonged bleeding time (HP:0003010)2.19477529
72Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.17883462
73Abnormality of reticulocytes (HP:0004312)2.17378341
74Thyroiditis (HP:0100646)2.16522337
75Acute myeloid leukemia (HP:0004808)2.15173320
76Type 2 muscle fiber atrophy (HP:0003554)2.14062297
77Bone marrow hypocellularity (HP:0005528)2.13215942
78Abnormality of the fingertips (HP:0001211)2.12193864
79Severe combined immunodeficiency (HP:0004430)2.11467261
80Tongue fasciculations (HP:0001308)2.10332935
81Cellulitis (HP:0100658)2.10119798
82Abnormality of the carotid arteries (HP:0005344)2.09159454
83Abnormal umbilical cord blood vessels (HP:0011403)2.08316597
84Single umbilical artery (HP:0001195)2.08316597
85Abnormality of the fetal cardiovascular system (HP:0010948)2.08316597
86Recurrent bacterial skin infections (HP:0005406)2.06830222
87Muscle fiber atrophy (HP:0100295)2.05589262
88Increased nuchal translucency (HP:0010880)2.05163120
89Medulloblastoma (HP:0002885)2.05124125
90Abnormality of DNA repair (HP:0003254)2.04691125
91Myositis (HP:0100614)2.04541444
92Oral leukoplakia (HP:0002745)2.04490524
93Aplasia/Hypoplasia of the uvula (HP:0010293)2.01527305
94Spastic diplegia (HP:0001264)1.99813707
95Abnormal lung lobation (HP:0002101)1.99771499
96Optic nerve coloboma (HP:0000588)1.99347742
97Lymphopenia (HP:0001888)1.99325096
98Abnormality of cells of the lymphoid lineage (HP:0012140)1.98991761
99Septate vagina (HP:0001153)1.98498450
100Abnormal delayed hypersensitivity skin test (HP:0002963)1.97429440
101Meckel diverticulum (HP:0002245)1.97390178
102Abnormality of the ileum (HP:0001549)1.97335200
103Long palpebral fissure (HP:0000637)1.97116655
104Hypoparathyroidism (HP:0000829)1.95346464
105Overriding aorta (HP:0002623)1.95315991
106Abnormality of T cell physiology (HP:0011840)1.95182892
107Partial duplication of thumb phalanx (HP:0009944)1.94361135
108Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94355341
109Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94355341
110Maternal diabetes (HP:0009800)1.91009099
111Impulsivity (HP:0100710)1.89911941
112Premature graying of hair (HP:0002216)1.89561714
113Triphalangeal thumb (HP:0001199)1.89384797
114Hypoplastic left heart (HP:0004383)1.88796982
115Abnormal ventriculo-arterial connection (HP:0011563)1.88524228
116Transposition of the great arteries (HP:0001669)1.88524228
117Abnormal connection of the cardiac segments (HP:0011545)1.88524228
118Combined immunodeficiency (HP:0005387)1.88232464
119Facial cleft (HP:0002006)1.88099364
120Duplication of thumb phalanx (HP:0009942)1.85361496
121Overlapping toe (HP:0001845)1.85344474
122Recurrent otitis media (HP:0000403)1.85304843
123Elevated erythrocyte sedimentation rate (HP:0003565)1.85213052
124Autoimmune thrombocytopenia (HP:0001973)1.83531918
125Absent thumb (HP:0009777)1.83382862
126Eczematoid dermatitis (HP:0000976)1.83044122
127Elfin facies (HP:0004428)1.82470650
128Mediastinal lymphadenopathy (HP:0100721)1.81662052
129Pustule (HP:0200039)1.80752353
130Abnormality of the prostate (HP:0008775)1.79877994
131Sloping forehead (HP:0000340)1.79044053
132Macrocytic anemia (HP:0001972)1.78703824
133Meningitis (HP:0001287)1.77732072
134Pulmonary fibrosis (HP:0002206)1.76847630
135Renovascular hypertension (HP:0100817)1.76538394
136Postnatal microcephaly (HP:0005484)1.75958331
137Prominent metopic ridge (HP:0005487)1.75715427
138Bifid tongue (HP:0010297)1.75689461
139Small intestinal stenosis (HP:0012848)1.75333233
140Duodenal stenosis (HP:0100867)1.75333233
141Rough bone trabeculation (HP:0100670)1.75267383
142Abnormal mitochondria in muscle tissue (HP:0008316)1.75254084
143Increased serum pyruvate (HP:0003542)1.75114861
144Secondary amenorrhea (HP:0000869)1.74155988
145Nephroblastoma (Wilms tumor) (HP:0002667)1.73852400
146Type I transferrin isoform profile (HP:0003642)1.72702496
147Clubbing of toes (HP:0100760)1.72686353
148Cellular immunodeficiency (HP:0005374)1.72419475
149Abnormality of glycolysis (HP:0004366)1.71944185
150Renal duplication (HP:0000075)1.71644816
151Entropion (HP:0000621)1.70363364
152Hypoplasia of the capital femoral epiphysis (HP:0003090)1.70348150
153Increased intramyocellular lipid droplets (HP:0012240)1.70106312
154Asplenia (HP:0001746)1.69642400
155Aplasia/Hypoplasia of the breasts (HP:0010311)1.69535414
156Anophthalmia (HP:0000528)1.69262639
157Male infertility (HP:0003251)1.68932554
158Septo-optic dysplasia (HP:0100842)1.68778959
159Pterygium (HP:0001059)1.68457495
160Adrenal hypoplasia (HP:0000835)1.67675442
161Sparse eyelashes (HP:0000653)1.67165866
162Hyperglycinemia (HP:0002154)1.66683433
163Ragged-red muscle fibers (HP:0003200)1.66370091
164Upper limb muscle weakness (HP:0003484)1.66335917
165Abnormality of the distal phalanges of the toes (HP:0010182)1.66123030
166Increased hepatocellular lipid droplets (HP:0006565)1.65549762
167Abnormalities of placenta or umbilical cord (HP:0001194)1.64720729
168Pelvic girdle muscle weakness (HP:0003749)1.62967479
169Glossoptosis (HP:0000162)1.62522728
170Preauricular skin tag (HP:0000384)1.62242824
171Absent radius (HP:0003974)1.61436213
172Generalized hypotonia (HP:0001290)1.61099252
173Absent forearm bone (HP:0003953)1.58250066
174Aplasia involving forearm bones (HP:0009822)1.58250066
175Vertebral hypoplasia (HP:0008417)1.58022328
176Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.58022328
177Cholecystitis (HP:0001082)1.57421587
178Abnormal gallbladder physiology (HP:0012438)1.57421587
179Back pain (HP:0003418)1.56742813
180Abnormal tarsal ossification (HP:0008369)1.56361859
181Trigonocephaly (HP:0000243)1.55129558
182Insidious onset (HP:0003587)1.55021473
183Termporal pattern (HP:0011008)1.55021473
184Short nail (HP:0001799)1.54393904
185Abnormality of the anterior horn cell (HP:0006802)1.53889627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.34202727
2MAP4K13.43609990
3SMG13.08505840
4WEE12.96376042
5EEF2K2.90350494
6CDC72.69002228
7BUB12.57498137
8TAF12.47500823
9STK162.46755426
10NEK22.44635175
11BRSK22.38993274
12PASK2.33776523
13PDK32.28720309
14PDK42.28720309
15BTK2.22538097
16TXK2.20356562
17ZAP702.16108977
18TSSK61.97850923
19NME21.96700126
20KIT1.91048763
21FLT31.77908117
22RPS6KB21.74708925
23SCYL21.73226799
24TYK21.71664842
25ICK1.66304263
26SRPK11.64870524
27PLK41.64793795
28STK101.64603301
29TEC1.63072839
30RPS6KA41.59827943
31TESK11.52448710
32BCKDK1.51724014
33MAP2K71.50179586
34JAK31.48332603
35PBK1.47413500
36TRIM281.45647310
37ATR1.43642138
38SYK1.41582789
39DYRK31.39409075
40PAK41.35530464
41CCNB11.35277196
42ARAF1.34354217
43EPHB21.32680234
44CDK121.30358404
45YES11.28484209
46VRK11.28198492
47CDK71.27075765
48BRAF1.25863993
49IKBKE1.24915642
50NME11.24693127
51ITK1.20331653
52MAP2K31.20252071
53MAP3K101.16685108
54TLK11.15508907
55AURKB1.14832517
56PLK11.12587944
57EIF2AK31.11286488
58BRSK11.11213297
59CSNK1G31.09110517
60PDK21.08382440
61ACVR1B1.07184861
62NUAK11.06011868
63GRK61.03995817
64DYRK21.02383462
65CSF1R1.00544156
66CHEK20.99105725
67TGFBR10.98577268
68CDK90.97276573
69TESK20.97027903
70PIM20.96059611
71EIF2AK10.95856639
72LCK0.95386196
73CDK40.93087335
74CHEK10.92669916
75NLK0.88901012
76BRD40.88050231
77PIM10.87983686
78MAPKAPK30.87365499
79CSNK1A1L0.86579243
80TAOK20.86198136
81CSNK1G10.85852347
82ERBB40.83611708
83CSNK1G20.83596876
84IKBKB0.83253420
85LYN0.82938247
86HCK0.79960073
87TBK10.79631269
88TTK0.76684423
89LATS20.72962652
90PNCK0.72694716
91SIK10.72217958
92STK40.72128996
93MAP3K80.70529587
94MAP3K90.70213361
95MAP3K110.68372466
96ZAK0.68351762
97EIF2AK20.67103221
98MAP3K140.66964532
99ALK0.66387594
100MARK30.65811539
101IRAK40.63687964
102MAP3K30.63393862
103NEK10.62968411
104LRRK20.62248247
105CLK10.61753663
106BMPR1B0.58436792
107ATM0.56276132
108DMPK0.54986571
109BLK0.54779097
110LIMK10.54629016
111RAF10.54475196
112BCR0.53948333
113CDK11A0.53728919
114DAPK10.52793414
115PLK30.52479474
116CDK10.52371098
117EPHA20.52325396
118MKNK10.51952342
119CDK140.51773583
120IRAK30.50912341
121RPS6KA50.50250911
122CDK20.50140504
123MKNK20.49809524
124CHUK0.48953818
125AKT20.48820494
126CDK150.46581905
127KDR0.46179517
128PRKD30.46059723
129WNK30.45950361
130STK30.45690415
131BMX0.45514845
132CDK180.45379958
133MAPKAPK50.44422331
134MAPKAPK20.44211196
135CSNK2A20.43665669
136PRKCI0.42805299
137FGFR30.42176739
138CSNK1E0.40982776
139MAP3K40.38883693
140PAK10.36167762
141FGFR10.36066766
142CDK190.35814187
143AURKA0.35497921
144CAMK1D0.34979447
145CDK60.34731575
146CSNK2A10.32766307
147TNIK0.30749651
148MST40.29455774
149MAPK110.28701367

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.60204351
2Mismatch repair_Homo sapiens_hsa034303.15336482
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.74583866
4Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.52268800
5Homologous recombination_Homo sapiens_hsa034402.49946486
6Spliceosome_Homo sapiens_hsa030402.47883125
7Base excision repair_Homo sapiens_hsa034102.43814406
8Ribosome_Homo sapiens_hsa030102.37770590
9RNA transport_Homo sapiens_hsa030132.33777848
10Primary immunodeficiency_Homo sapiens_hsa053402.26402538
11RNA polymerase_Homo sapiens_hsa030202.14202937
12Steroid biosynthesis_Homo sapiens_hsa001002.09735056
13Nucleotide excision repair_Homo sapiens_hsa034202.09658616
14Fanconi anemia pathway_Homo sapiens_hsa034602.04953796
15Basal transcription factors_Homo sapiens_hsa030222.04357965
16Cell cycle_Homo sapiens_hsa041102.03512154
17One carbon pool by folate_Homo sapiens_hsa006702.00285147
18Non-homologous end-joining_Homo sapiens_hsa034501.99766344
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.97654968
20Antigen processing and presentation_Homo sapiens_hsa046121.97437629
21Biosynthesis of amino acids_Homo sapiens_hsa012301.91490439
22Pyrimidine metabolism_Homo sapiens_hsa002401.86885577
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.84919253
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.70828866
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.67186834
26Measles_Homo sapiens_hsa051621.60324882
27Systemic lupus erythematosus_Homo sapiens_hsa053221.58638541
28Proteasome_Homo sapiens_hsa030501.56752469
29Folate biosynthesis_Homo sapiens_hsa007901.53849794
30Legionellosis_Homo sapiens_hsa051341.52624044
31Herpes simplex infection_Homo sapiens_hsa051681.51949251
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.51028897
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.49965385
34Protein export_Homo sapiens_hsa030601.49776210
35RNA degradation_Homo sapiens_hsa030181.45904170
36p53 signaling pathway_Homo sapiens_hsa041151.45222770
37Hematopoietic cell lineage_Homo sapiens_hsa046401.44374143
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.41178982
39Fatty acid elongation_Homo sapiens_hsa000621.38434827
40mRNA surveillance pathway_Homo sapiens_hsa030151.35390370
41Pentose phosphate pathway_Homo sapiens_hsa000301.29249722
42B cell receptor signaling pathway_Homo sapiens_hsa046621.29249494
43Basal cell carcinoma_Homo sapiens_hsa052171.28162689
44Carbon metabolism_Homo sapiens_hsa012001.27911395
45Intestinal immune network for IgA production_Homo sapiens_hsa046721.27616500
46Viral carcinogenesis_Homo sapiens_hsa052031.24521399
47Epstein-Barr virus infection_Homo sapiens_hsa051691.23059649
48Leishmaniasis_Homo sapiens_hsa051401.22088643
49Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.20333389
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17632743
51Parkinsons disease_Homo sapiens_hsa050121.17420222
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.15820281
53Pyruvate metabolism_Homo sapiens_hsa006201.15720622
54T cell receptor signaling pathway_Homo sapiens_hsa046601.14077830
55Purine metabolism_Homo sapiens_hsa002301.12655651
56Huntingtons disease_Homo sapiens_hsa050161.12257930
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.11899180
58Allograft rejection_Homo sapiens_hsa053301.09719503
59Oxidative phosphorylation_Homo sapiens_hsa001901.09540307
60Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07218946
61Influenza A_Homo sapiens_hsa051640.99287023
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.97709981
63Hepatitis B_Homo sapiens_hsa051610.96822496
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.94683026
65HTLV-I infection_Homo sapiens_hsa051660.94262851
66N-Glycan biosynthesis_Homo sapiens_hsa005100.92442141
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.91607162
68Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89623016
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.87000181
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.86498749
71Hippo signaling pathway_Homo sapiens_hsa043900.85100166
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.84382990
73Toll-like receptor signaling pathway_Homo sapiens_hsa046200.83607700
74Osteoclast differentiation_Homo sapiens_hsa043800.83019289
75Acute myeloid leukemia_Homo sapiens_hsa052210.81356149
76Chronic myeloid leukemia_Homo sapiens_hsa052200.79355845
77Apoptosis_Homo sapiens_hsa042100.76796172
78Toxoplasmosis_Homo sapiens_hsa051450.75306309
79Shigellosis_Homo sapiens_hsa051310.70972260
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.70740953
81Wnt signaling pathway_Homo sapiens_hsa043100.69740444
82Hedgehog signaling pathway_Homo sapiens_hsa043400.69547764
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68708558
84Graft-versus-host disease_Homo sapiens_hsa053320.68703226
85Small cell lung cancer_Homo sapiens_hsa052220.66956991
86Glutathione metabolism_Homo sapiens_hsa004800.66818426
87Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65770005
88Selenocompound metabolism_Homo sapiens_hsa004500.65763544
89Alcoholism_Homo sapiens_hsa050340.64274417
90Colorectal cancer_Homo sapiens_hsa052100.63118713
91Lysine degradation_Homo sapiens_hsa003100.62887629
92Vitamin B6 metabolism_Homo sapiens_hsa007500.62086226
93Thyroid cancer_Homo sapiens_hsa052160.62005609
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.60052768
95Oocyte meiosis_Homo sapiens_hsa041140.57815609
96Galactose metabolism_Homo sapiens_hsa000520.57382348
97TGF-beta signaling pathway_Homo sapiens_hsa043500.57217781
98Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.56757856
99Adherens junction_Homo sapiens_hsa045200.56532812
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56359727
101Fructose and mannose metabolism_Homo sapiens_hsa000510.55120971
102Asthma_Homo sapiens_hsa053100.55114392
103Propanoate metabolism_Homo sapiens_hsa006400.54691969
104Bladder cancer_Homo sapiens_hsa052190.53979118
105Vibrio cholerae infection_Homo sapiens_hsa051100.53962628
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53730583
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53606729
108Pertussis_Homo sapiens_hsa051330.53193343
109Endometrial cancer_Homo sapiens_hsa052130.52491700
110Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.51989487
111Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51237346
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51048964
113Metabolic pathways_Homo sapiens_hsa011000.50853573
114TNF signaling pathway_Homo sapiens_hsa046680.50842111
115Type I diabetes mellitus_Homo sapiens_hsa049400.50770439
116Inositol phosphate metabolism_Homo sapiens_hsa005620.50744908
117Autoimmune thyroid disease_Homo sapiens_hsa053200.50534889
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50096574
119Fatty acid metabolism_Homo sapiens_hsa012120.45832657
120Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45749985
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45161351
122Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44052956
123Prostate cancer_Homo sapiens_hsa052150.43942233
124Alzheimers disease_Homo sapiens_hsa050100.43765008
125Sulfur relay system_Homo sapiens_hsa041220.43297261
126Viral myocarditis_Homo sapiens_hsa054160.42989663
127Arginine and proline metabolism_Homo sapiens_hsa003300.42627502
128Malaria_Homo sapiens_hsa051440.42564896
129Platelet activation_Homo sapiens_hsa046110.41193022
130SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41114362
131Pancreatic cancer_Homo sapiens_hsa052120.40869963
132Notch signaling pathway_Homo sapiens_hsa043300.40782625
133Cysteine and methionine metabolism_Homo sapiens_hsa002700.40558538
134Tuberculosis_Homo sapiens_hsa051520.40359726
135Non-small cell lung cancer_Homo sapiens_hsa052230.39732298
136Hepatitis C_Homo sapiens_hsa051600.39413463
137Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39264165
138Other glycan degradation_Homo sapiens_hsa005110.38694926
139Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38106553
140MicroRNAs in cancer_Homo sapiens_hsa052060.37016122
141Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35759005
142Leukocyte transendothelial migration_Homo sapiens_hsa046700.35549382
143Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34638924
144Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34171607
145Drug metabolism - other enzymes_Homo sapiens_hsa009830.32644837
146Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.32433208
147Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31977259
148Chemokine signaling pathway_Homo sapiens_hsa040620.30205077
149HIF-1 signaling pathway_Homo sapiens_hsa040660.29465664
150Melanoma_Homo sapiens_hsa052180.25327649
151Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21417391
152Sulfur metabolism_Homo sapiens_hsa009200.20794751
153AMPK signaling pathway_Homo sapiens_hsa041520.20049235

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