ZBTB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1definitive hemopoiesis (GO:0060216)5.21068801
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.93510193
3negative regulation of cell killing (GO:0031342)4.93510193
4regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.24793839
5positive regulation of gamma-delta T cell activation (GO:0046645)4.02206859
6response to muramyl dipeptide (GO:0032495)3.79262760
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.66765883
8positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.57229297
9positive regulation of chemokine secretion (GO:0090197)3.56506949
10thymic T cell selection (GO:0045061)3.54305799
11histone H3-K36 demethylation (GO:0070544)3.49580180
12negative regulation of T cell mediated immunity (GO:0002710)3.44661375
13regulation of tolerance induction (GO:0002643)3.44625343
14cellular extravasation (GO:0045123)3.44187828
15regulation of DNA endoreduplication (GO:0032875)3.43001542
16tRNA methylation (GO:0030488)3.37782203
17neutrophil activation involved in immune response (GO:0002283)3.27986895
18megakaryocyte development (GO:0035855)3.12638358
19embryonic process involved in female pregnancy (GO:0060136)3.10926138
20negative regulation of lymphocyte mediated immunity (GO:0002707)3.10222619
21negative T cell selection (GO:0043383)3.08262313
22positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.08000821
23lymphoid progenitor cell differentiation (GO:0002320)3.05488458
24antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.03347688
25antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.03347688
26interferon-gamma production (GO:0032609)3.03213353
27phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.99258484
28germinal center formation (GO:0002467)2.99256939
29regulation of germinal center formation (GO:0002634)2.96548752
30detection of other organism (GO:0098543)2.94034430
31positive regulation of mast cell activation (GO:0033005)2.93312556
32macrophage activation involved in immune response (GO:0002281)2.93181454
33positive regulation by symbiont of host defense response (GO:0052509)2.92640683
34modulation by symbiont of host defense response (GO:0052031)2.92640683
35modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.92640683
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.92640683
37positive regulation by organism of defense response of other organism involved in symbiotic interact2.92640683
38modulation by symbiont of host immune response (GO:0052553)2.92640683
39tolerance induction (GO:0002507)2.92453941
40regulation of interferon-beta biosynthetic process (GO:0045357)2.91677727
41NIK/NF-kappaB signaling (GO:0038061)2.91583025
42positive regulation of alpha-beta T cell proliferation (GO:0046641)2.91334773
43regulation of chemokine secretion (GO:0090196)2.90437761
44histone H3-K9 demethylation (GO:0033169)2.88206430
45V(D)J recombination (GO:0033151)2.87952878
46leukocyte aggregation (GO:0070486)2.87751901
47negative thymic T cell selection (GO:0045060)2.87709176
48T cell homeostasis (GO:0043029)2.84030445
49* positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)2.81815696
50positive regulation of megakaryocyte differentiation (GO:0045654)2.81815696
51regulation of mast cell degranulation (GO:0043304)2.81756460
52negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.80500040
53negative regulation of T-helper cell differentiation (GO:0045623)2.80500040
54embryonic hemopoiesis (GO:0035162)2.80336358
55regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.78603499
56T cell differentiation involved in immune response (GO:0002292)2.78336240
57alpha-beta T cell differentiation involved in immune response (GO:0002293)2.78336240
58alpha-beta T cell activation involved in immune response (GO:0002287)2.78336240
59response to interleukin-15 (GO:0070672)2.78265388
60myeloid cell activation involved in immune response (GO:0002275)2.78001737
61detection of bacterium (GO:0016045)2.77806177
62positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.77669558
63immunoglobulin mediated immune response (GO:0016064)2.77667196
64regulation of mast cell activation involved in immune response (GO:0033006)2.77227313
65interferon-gamma-mediated signaling pathway (GO:0060333)2.76885576
66myeloid dendritic cell activation (GO:0001773)2.76443344
67CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.76333256
68granulocyte activation (GO:0036230)2.75340400
69regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.74812092
70regulation of T cell mediated cytotoxicity (GO:0001914)2.73905803
71antigen processing and presentation of endogenous antigen (GO:0019883)2.72993734
72positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.72543086
73positive regulation of interleukin-2 production (GO:0032743)2.72313607
74regulation of gamma-delta T cell differentiation (GO:0045586)2.72129348
75T cell receptor signaling pathway (GO:0050852)2.69133889
76response to peptidoglycan (GO:0032494)2.69040241
77positive regulation of mast cell degranulation (GO:0043306)2.68732520
78positive regulation of mast cell activation involved in immune response (GO:0033008)2.68732520
79mature B cell differentiation involved in immune response (GO:0002313)2.67552394
80Arp2/3 complex-mediated actin nucleation (GO:0034314)2.67509200
81regulation of gamma-delta T cell activation (GO:0046643)2.66601352
82T cell costimulation (GO:0031295)2.66519698
83regulation of T cell receptor signaling pathway (GO:0050856)2.66472665
84positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.66082958
85negative regulation of interleukin-12 production (GO:0032695)2.65655777
86angiogenesis involved in wound healing (GO:0060055)2.65629656
87hepatocyte apoptotic process (GO:0097284)2.65291215
88regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.65196510
89antigen processing and presentation via MHC class Ib (GO:0002475)2.65163694
90lymphocyte costimulation (GO:0031294)2.64871524
91maturation of SSU-rRNA (GO:0030490)2.63787766
92positive regulation of interferon-alpha production (GO:0032727)2.62939718
93regulation of B cell receptor signaling pathway (GO:0050855)2.62709770
94negative regulation of leukocyte mediated immunity (GO:0002704)2.62291241
95negative regulation of macrophage differentiation (GO:0045650)2.61826567
96regulation of mast cell activation (GO:0033003)2.61144582
97cellular response to interleukin-15 (GO:0071350)2.60958006
98positive regulation of tolerance induction (GO:0002645)2.60803622
99ribosomal small subunit assembly (GO:0000028)2.60701979
100mature B cell differentiation (GO:0002335)2.60664286
101regulation of fibroblast apoptotic process (GO:2000269)2.60483560
102regulation of B cell proliferation (GO:0030888)2.59889675
103lymph node development (GO:0048535)2.59723538
104regulation of alpha-beta T cell activation (GO:0046634)2.59288402
105dendritic cell chemotaxis (GO:0002407)2.57560180
106RNA-dependent DNA replication (GO:0006278)2.57029406
107positive regulation of B cell differentiation (GO:0045579)2.55759812
108positive regulation of granulocyte differentiation (GO:0030854)2.54583526
109telomere maintenance via recombination (GO:0000722)2.52756372
110pseudouridine synthesis (GO:0001522)2.52248120
111regulation of centriole replication (GO:0046599)2.51790088
112positive regulation of interleukin-8 secretion (GO:2000484)2.51514286
113centriole assembly (GO:0098534)2.50895977
114regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.48668253
115lymphocyte homeostasis (GO:0002260)2.47830657
116* T cell differentiation (GO:0030217)2.47310604
117regulation of regulatory T cell differentiation (GO:0045589)2.47187064
118negative regulation of phagocytosis (GO:0050765)2.44947297
119regulation of B cell differentiation (GO:0045577)2.44262258
120regulation of histone H3-K27 methylation (GO:0061085)2.43965761
121B cell homeostasis (GO:0001782)2.42651690
122pinocytosis (GO:0006907)2.41213095
123negative regulation of DNA-dependent DNA replication (GO:2000104)2.40348911
124regulation of antigen processing and presentation (GO:0002577)2.40168208
125telomere maintenance via semi-conservative replication (GO:0032201)2.40011634
126negative regulation of granulocyte differentiation (GO:0030853)2.39814315
127mast cell activation (GO:0045576)2.39397332
128DNA ligation (GO:0006266)2.38596314
129positive T cell selection (GO:0043368)2.38380652
130positive regulation of antigen processing and presentation (GO:0002579)2.36467706
131positive thymic T cell selection (GO:0045059)2.35969742
132telomere maintenance (GO:0000723)2.35860169
133B cell receptor signaling pathway (GO:0050853)2.35242796
134DNA synthesis involved in DNA repair (GO:0000731)2.35089655
135regulation of alpha-beta T cell proliferation (GO:0046640)2.34875935
136alpha-beta T cell activation (GO:0046631)2.34792923
137mitotic recombination (GO:0006312)2.34198502
138meiotic chromosome segregation (GO:0045132)2.33177254
139homeostasis of number of cells within a tissue (GO:0048873)2.31456315
140germ cell migration (GO:0008354)2.31363090
141telomere organization (GO:0032200)2.31353145
142T cell selection (GO:0045058)2.30969138
143regulation of interleukin-12 biosynthetic process (GO:0045075)2.30788136
144positive regulation of defense response to virus by host (GO:0002230)2.30677580
145dendritic cell migration (GO:0036336)2.27723723
146alpha-beta T cell differentiation (GO:0046632)2.27507184
147regulation of T cell tolerance induction (GO:0002664)2.27153503
148histone mRNA catabolic process (GO:0071044)2.26996440
149negative regulation of B cell proliferation (GO:0030889)2.26785097
150neutrophil activation (GO:0042119)2.26390119
151antigen receptor-mediated signaling pathway (GO:0050851)2.25647461
152regulation of macrophage differentiation (GO:0045649)2.24544080
153DNA deamination (GO:0045006)2.23868702
154T cell lineage commitment (GO:0002360)2.23440789
155regulation of necroptotic process (GO:0060544)2.22779949
156leukocyte homeostasis (GO:0001776)2.22020109
157T cell migration (GO:0072678)2.20689397
158energy homeostasis (GO:0097009)2.20495195
159regulation of granulocyte differentiation (GO:0030852)2.19811836
160T-helper cell differentiation (GO:0042093)2.18383097
161CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.18383097
162cellular response to interferon-beta (GO:0035458)2.16683468
163telomere maintenance via telomerase (GO:0007004)2.15941661
164kinetochore organization (GO:0051383)2.15390518
165* lymphocyte differentiation (GO:0030098)2.15367757

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.67963660
2* FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.72403630
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.67500619
4GATA1_22025678_ChIP-Seq_K562_Human3.36507249
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.24622514
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.03279369
7NOTCH1_21737748_ChIP-Seq_TLL_Human3.01864581
8SCL_19346495_ChIP-Seq_HPC-7_Human2.82066371
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.81626683
10* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.68965630
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.64398521
12EGR1_19374776_ChIP-ChIP_THP-1_Human2.62961518
13RUNX_20019798_ChIP-Seq_JUKART_Human2.54044076
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.45163285
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.31882143
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.27966874
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.25224318
18* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.21839165
19MYB_26560356_Chip-Seq_TH2_Human2.08408252
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.03407772
21VDR_24787735_ChIP-Seq_THP-1_Human2.00872021
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.97595957
23FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.97493887
24TP63_19390658_ChIP-ChIP_HaCaT_Human1.92018165
25* SPI1_23547873_ChIP-Seq_NB4_Human1.85745636
26ELK1_19687146_ChIP-ChIP_HELA_Human1.84300210
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.78359330
28MYB_26560356_Chip-Seq_TH1_Human1.77633628
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.77533481
30IRF8_21731497_ChIP-ChIP_J774_Mouse1.74938093
31GATA3_26560356_Chip-Seq_TH2_Human1.72727739
32SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.71765715
33IRF8_27001747_Chip-Seq_BMDM_Mouse1.71109390
34ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.69758304
35FOXM1_23109430_ChIP-Seq_U2OS_Human1.67628353
36MYB_21317192_ChIP-Seq_ERMYB_Mouse1.65754633
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.63907040
38* TCF7_22412390_ChIP-Seq_EML_Mouse1.62816515
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62621938
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.60158512
41* E2F1_21310950_ChIP-Seq_MCF-7_Human1.59838179
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57264356
43* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.55143513
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51340837
45PCGF2_27294783_Chip-Seq_NPCs_Mouse1.50003723
46* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48595504
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.47928532
48* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.47699117
49NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.47412359
50STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.46784727
51MYC_22102868_ChIP-Seq_BL_Human1.46509763
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46060552
53KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.46058053
54VDR_23849224_ChIP-Seq_CD4+_Human1.44428092
55FLI1_27457419_Chip-Seq_LIVER_Mouse1.41040214
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.40365285
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.39311028
58E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.39008845
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36489273
60GATA2_21666600_ChIP-Seq_HMVEC_Human1.35661519
61RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.34561848
62MAF_26560356_Chip-Seq_TH1_Human1.32809049
63WT1_19549856_ChIP-ChIP_CCG9911_Human1.32519139
64MYC_18555785_ChIP-Seq_MESCs_Mouse1.32239236
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.32091401
66RUNX1_22412390_ChIP-Seq_EML_Mouse1.31915917
67RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29123440
68FOXP3_21729870_ChIP-Seq_TREG_Human1.27925000
69KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.27767505
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.26450737
71IRF1_19129219_ChIP-ChIP_H3396_Human1.25585347
72SALL1_21062744_ChIP-ChIP_HESCs_Human1.25513917
73PU_27001747_Chip-Seq_BMDM_Mouse1.23446535
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.22040121
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.20601573
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.19896803
77MAF_26560356_Chip-Seq_TH2_Human1.19522525
78LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.17474745
79ESR1_20079471_ChIP-ChIP_T-47D_Human1.15867691
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.15306885
81SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14198685
82* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13681802
83KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10296881
84CIITA_25753668_ChIP-Seq_RAJI_Human1.09019906
85CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.08105317
86VDR_24763502_ChIP-Seq_THP-1_Human1.08081274
87UTX_26944678_Chip-Seq_JUKART_Human1.07972331
88VDR_21846776_ChIP-Seq_THP-1_Human1.07944409
89BRD4_27068464_Chip-Seq_AML-cells_Mouse1.05362727
90NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02361840
91PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02196569
92CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.01153226
93EZH2_27294783_Chip-Seq_NPCs_Mouse1.01119120
94FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.98497128
95KDM2B_26808549_Chip-Seq_DND41_Human0.97977939
96GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97582903
97* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.95687584
98MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.95526839
99GATA3_27048872_Chip-Seq_THYMUS_Human0.94524921
100SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.93396576
101LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.92435433
102SPI1_23127762_ChIP-Seq_K562_Human0.91132273
103TFEB_21752829_ChIP-Seq_HELA_Human0.90905036
104EWS_26573619_Chip-Seq_HEK293_Human0.90052933
105BRD4_25478319_ChIP-Seq_HGPS_Human0.89838028
106TP63_17297297_ChIP-ChIP_HaCaT_Human0.89228876
107FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.89060422
108FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.87095976
109FOXO3_23340844_ChIP-Seq_DLD1_Human0.86471963
110GATA1_19941826_ChIP-Seq_K562_Human0.85609848
111STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83051406
112PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82543557
113* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.81913653
114* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.81913653
115KDM2B_26808549_Chip-Seq_JURKAT_Human0.81729274
116KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.81659386
117EST1_17652178_ChIP-ChIP_JURKAT_Human0.81384034
118GATA2_22383799_ChIP-Seq_G1ME_Mouse0.81133909
119CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.80484798
120SMRT_27268052_Chip-Seq_Bcells_Human0.79835935
121ZNF217_24962896_ChIP-Seq_MCF-7_Human0.79492748
122NELFA_20434984_ChIP-Seq_ESCs_Mouse0.78855278
123GABP_17652178_ChIP-ChIP_JURKAT_Human0.78126106
124* MYC_19030024_ChIP-ChIP_MESCs_Mouse0.77893271
125KDM2B_26808549_Chip-Seq_SUP-B15_Human0.77871129
126GATA2_19941826_ChIP-Seq_K562_Human0.77869022
127CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.76985179
128ETS1_22383799_ChIP-Seq_G1ME_Mouse0.76707243
129POU5F1_16153702_ChIP-ChIP_HESCs_Human0.76667599
130GATA3_26560356_Chip-Seq_TH1_Human0.75559405
131AHR_22903824_ChIP-Seq_MCF-7_Human0.75374969
132Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.74908986
133SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74406259
134PPAR_26484153_Chip-Seq_NCI-H1993_Human0.72715352
135CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.71792844
136GATA1_19941827_ChIP-Seq_MEL_Mouse0.70416401
137VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.67331219
138GATA1_22383799_ChIP-Seq_G1ME_Mouse0.67305801

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.31519605
2MP0002396_abnormal_hematopoietic_system3.23919921
3MP0005174_abnormal_tail_pigmentation2.69221790
4MP0003763_abnormal_thymus_physiology2.66067774
5MP0003950_abnormal_plasma_membrane2.53942099
6MP0005671_abnormal_response_to2.53021393
7MP0001835_abnormal_antigen_presentation2.51174343
8MP0008007_abnormal_cellular_replicative2.36894791
9MP0004808_abnormal_hematopoietic_stem2.31520016
10MP0000015_abnormal_ear_pigmentation2.15203633
11MP0003303_peritoneal_inflammation2.05723686
12MP0001800_abnormal_humoral_immune2.01055848
13MP0010094_abnormal_chromosome_stability1.98125108
14MP0000465_gastrointestinal_hemorrhage1.92103445
15MP0002166_altered_tumor_susceptibility1.88071398
16MP0002398_abnormal_bone_marrow1.87715482
17MP0003828_pulmonary_edema1.85085561
18MP0002452_abnormal_antigen_presenting1.84643313
19MP0005000_abnormal_immune_tolerance1.82252655
20MP0006082_CNS_inflammation1.81081785
21MP0001790_abnormal_immune_system1.79107566
22MP0005387_immune_system_phenotype1.79107566
23MP0000685_abnormal_immune_system1.78738824
24MP0002095_abnormal_skin_pigmentation1.74944006
25MP0002420_abnormal_adaptive_immunity1.73858382
26MP0002723_abnormal_immune_serum1.71041763
27MP0008438_abnormal_cutaneous_collagen1.70141922
28MP0001819_abnormal_immune_cell1.69886717
29MP0004381_abnormal_hair_follicle1.66870762
30MP0005075_abnormal_melanosome_morpholog1.63017440
31MP0003724_increased_susceptibility_to1.62514221
32MP0002006_tumorigenesis1.61868673
33MP0003191_abnormal_cellular_cholesterol1.61014354
34MP0008057_abnormal_DNA_replication1.60882718
35MP0005503_abnormal_tendon_morphology1.60769279
36MP0006054_spinal_hemorrhage1.59964109
37MP0002148_abnormal_hypersensitivity_rea1.59736561
38MP0003436_decreased_susceptibility_to1.56457628
39MP0002933_joint_inflammation1.56365993
40MP0009333_abnormal_splenocyte_physiolog1.56332624
41MP0000716_abnormal_immune_system1.54691532
42MP0001873_stomach_inflammation1.51911887
43MP0000703_abnormal_thymus_morphology1.50797513
44MP0001188_hyperpigmentation1.49244718
45MP0005025_abnormal_response_to1.47723797
46MP0005409_darkened_coat_color1.47015884
47MP0003111_abnormal_nucleus_morphology1.46942452
48MP0000689_abnormal_spleen_morphology1.46449386
49MP0001851_eye_inflammation1.45812088
50MP0003091_abnormal_cell_migration1.44813266
51MP0002722_abnormal_immune_system1.44099376
52MP0002419_abnormal_innate_immunity1.43941819
53MP0009785_altered_susceptibility_to1.42762180
54MP0002405_respiratory_system_inflammati1.42644162
55MP0002009_preneoplasia1.41968768
56MP0003172_abnormal_lysosome_physiology1.40476751
57MP0008260_abnormal_autophagy1.38898074
58MP0003077_abnormal_cell_cycle1.38147106
59MP0003183_abnormal_peptide_metabolism1.37800072
60MP0008058_abnormal_DNA_repair1.37268195
61MP0002429_abnormal_blood_cell1.35798526
62MP0000516_abnormal_urinary_system1.35188396
63MP0005367_renal/urinary_system_phenotyp1.35188396
64MP0005464_abnormal_platelet_physiology1.34247892
65MP0005171_absent_coat_pigmentation1.33013583
66MP0000490_abnormal_crypts_of1.30869343
67MP0010155_abnormal_intestine_physiology1.28909902
68MP0002877_abnormal_melanocyte_morpholog1.24350305
69MP0005397_hematopoietic_system_phenotyp1.23901742
70MP0001545_abnormal_hematopoietic_system1.23901742
71MP0001986_abnormal_taste_sensitivity1.22922343
72MP0003941_abnormal_skin_development1.21078537
73MP0004883_abnormal_blood_vessel1.19384824
74MP0001853_heart_inflammation1.17900655
75MP0003656_abnormal_erythrocyte_physiolo1.15664000
76MP0002060_abnormal_skin_morphology1.13628129
77MP0002132_abnormal_respiratory_system1.13586326
78MP0003300_gastrointestinal_ulcer1.09543677
79MP0005451_abnormal_body_composition1.09134301
80MP0000566_synostosis1.08896761
81MP0005275_abnormal_skin_tensile1.08315599
82MP0003943_abnormal_hepatobiliary_system1.07811096
83MP0009764_decreased_sensitivity_to1.05598833
84MP0006292_abnormal_olfactory_placode1.05363396
85MP0005076_abnormal_cell_differentiation1.05161421
86MP0010352_gastrointestinal_tract_polyps1.02924522
87MP0003279_aneurysm1.00836247
88MP0000249_abnormal_blood_vessel0.99574004
89MP0003866_abnormal_defecation0.98932974
90MP0002138_abnormal_hepatobiliary_system0.98571617
91MP0000858_altered_metastatic_potential0.97626663
92MP0005164_abnormal_response_to0.95291273
93MP0008469_abnormal_protein_level0.92197055
94MP0003221_abnormal_cardiomyocyte_apopto0.92106624
95MP0004947_skin_inflammation0.89419443
96MP0004264_abnormal_extraembryonic_tissu0.87365258
97MP0000371_diluted_coat_color0.85988649
98MP0005166_decreased_susceptibility_to0.85849954
99MP0000372_irregular_coat_pigmentation0.84398428
100MP0002075_abnormal_coat/hair_pigmentati0.84343811
101MP0009763_increased_sensitivity_to0.84108632
102MP0005390_skeleton_phenotype0.83378258
103MP0010307_abnormal_tumor_latency0.83019807
104MP0003786_premature_aging0.82780591
105MP0004134_abnormal_chest_morphology0.82420753
106MP0003693_abnormal_embryo_hatching0.82393342
107MP0005310_abnormal_salivary_gland0.81647088
108MP0002019_abnormal_tumor_incidence0.81570134
109MP0008961_abnormal_basal_metabolism0.81443182
110MP0009250_abnormal_appendicular_skeleto0.81256400
111MP0002177_abnormal_outer_ear0.81244498
112MP0002998_abnormal_bone_remodeling0.80665567
113MP0001845_abnormal_inflammatory_respons0.80293342
114MP0004147_increased_porphyrin_level0.79316392
115MP0003795_abnormal_bone_structure0.78761357
116MP0009278_abnormal_bone_marrow0.78502237
117MP0001533_abnormal_skeleton_physiology0.77187454
118MP0002938_white_spotting0.75925160
119MP0000613_abnormal_salivary_gland0.74578604
120MP0005058_abnormal_lysosome_morphology0.74243490
121MP0002277_abnormal_respiratory_mucosa0.73659723
122MP0003448_altered_tumor_morphology0.72735410
123MP0001243_abnormal_dermal_layer0.72610367
124MP0005621_abnormal_cell_physiology0.72417941
125MP0005508_abnormal_skeleton_morphology0.72342602
126MP0000383_abnormal_hair_follicle0.72072071
127MP0003566_abnormal_cell_adhesion0.72051220
128MP0009115_abnormal_fat_cell0.71657183
129MP0004185_abnormal_adipocyte_glucose0.71648828
130MP0009379_abnormal_foot_pigmentation0.70928824
131MP0005388_respiratory_system_phenotype0.67459498
132MP0002133_abnormal_respiratory_system0.67459498
133MP0004484_altered_response_of0.63982297
134MP0000604_amyloidosis0.62656632
135MP0003690_abnormal_glial_cell0.58150892
136MP0009765_abnormal_xenobiotic_induced0.56066131
137MP0005647_abnormal_sex_gland0.54358990

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)3.77105588
2Recurrent bronchitis (HP:0002837)3.55032667
3Autoimmune hemolytic anemia (HP:0001890)3.54346007
4Chronic sinusitis (HP:0011109)3.43063389
5Recurrent viral infections (HP:0004429)3.42355520
6Colitis (HP:0002583)3.27421277
7Abnormality of B cell number (HP:0010975)3.22640709
8B lymphocytopenia (HP:0010976)3.22640709
9Recurrent fungal infections (HP:0002841)3.21010826
10Acute myeloid leukemia (HP:0004808)3.20479184
11IgM deficiency (HP:0002850)3.10897661
12T lymphocytopenia (HP:0005403)3.08727216
13Abnormality of the fingertips (HP:0001211)3.04711989
14Gastrointestinal infarctions (HP:0005244)3.02067721
15Recurrent skin infections (HP:0001581)3.01729605
16Abnormality of T cell number (HP:0011839)2.94390686
17Inflammation of the large intestine (HP:0002037)2.94264261
18Prolonged bleeding time (HP:0003010)2.92009596
19Chronic otitis media (HP:0000389)2.90314763
20Spontaneous hematomas (HP:0007420)2.87364936
21Gastrointestinal inflammation (HP:0004386)2.77937140
22Panhypogammaglobulinemia (HP:0003139)2.73855715
23Viral hepatitis (HP:0006562)2.71953731
24Chest pain (HP:0100749)2.71198213
25IgG deficiency (HP:0004315)2.70327618
26Patchy hypopigmentation of hair (HP:0011365)2.63684510
27Pulmonary infiltrates (HP:0002113)2.63415192
28Abnormality of macrophages (HP:0004311)2.60542078
29Cellulitis (HP:0100658)2.59953468
30Neoplasm of the tracheobronchial system (HP:0100552)2.54738714
31Subacute progressive viral hepatitis (HP:0006572)2.52633257
32Elevated erythrocyte sedimentation rate (HP:0003565)2.51768902
33Myositis (HP:0100614)2.50352705
34Chromsome breakage (HP:0040012)2.49296705
35Encephalitis (HP:0002383)2.48050017
36Autoimmune thrombocytopenia (HP:0001973)2.45915791
37Menstrual irregularities (HP:0000858)2.45886489
38Fatigue (HP:0012378)2.43919618
39Severe combined immunodeficiency (HP:0004430)2.43491794
40Spinal cord lesions (HP:0100561)2.42131498
41Syringomyelia (HP:0003396)2.42131498
42Pustule (HP:0200039)2.41666149
43Leukocytosis (HP:0001974)2.41469590
44Stomatitis (HP:0010280)2.41001046
45Alveolar cell carcinoma (HP:0006519)2.39760754
46Hypoplasia of the thymus (HP:0000778)2.38907073
47Thrombocytosis (HP:0001894)2.37147864
48Chromosomal breakage induced by crosslinking agents (HP:0003221)2.36697473
49Gingivitis (HP:0000230)2.35930355
50Arterial thrombosis (HP:0004420)2.35681975
51Lymphoma (HP:0002665)2.32561155
52Thyroiditis (HP:0100646)2.32429038
53Slow saccadic eye movements (HP:0000514)2.31186397
54IgA deficiency (HP:0002720)2.30406953
55Lymphopenia (HP:0001888)2.28962076
56Osteomyelitis (HP:0002754)2.28422120
57Absent frontal sinuses (HP:0002688)2.26144769
58Eczematoid dermatitis (HP:0000976)2.25066647
59Persistence of primary teeth (HP:0006335)2.24674947
60Verrucae (HP:0200043)2.23766886
61Papilloma (HP:0012740)2.23766886
62Hemoptysis (HP:0002105)2.21979731
63Abnormality of T cells (HP:0002843)2.18898970
64Eosinophilia (HP:0001880)2.18761086
65Abnormality of glycolipid metabolism (HP:0010969)2.18697013
66Abnormality of liposaccharide metabolism (HP:0010968)2.18697013
67Abnormality of glycosphingolipid metabolism (HP:0004343)2.18697013
68Acute lymphatic leukemia (HP:0006721)2.17752964
69Abnormality of cells of the lymphoid lineage (HP:0012140)2.16954993
70White forelock (HP:0002211)2.16469213
71Petechiae (HP:0000967)2.15067824
72Keratoconjunctivitis sicca (HP:0001097)2.13537818
73Abnormality of eosinophils (HP:0001879)2.13161915
74Myelodysplasia (HP:0002863)2.12564176
75Lip pit (HP:0100267)2.12562332
76Increased IgE level (HP:0003212)2.12355354
77Recurrent abscess formation (HP:0002722)2.12166686
78Prominent nose (HP:0000448)2.11506442
79Agammaglobulinemia (HP:0004432)2.11321689
80Stomach cancer (HP:0012126)2.11302210
81Meningitis (HP:0001287)2.10945045
82Hematochezia (HP:0002573)2.09644090
83Retrobulbar optic neuritis (HP:0100654)2.08029172
84Optic neuritis (HP:0100653)2.08029172
85Pallor (HP:0000980)2.07820898
86Reticulocytopenia (HP:0001896)2.07615425
87Increased density of long bones (HP:0006392)2.06160103
88Papilledema (HP:0001085)2.05873395
89Granulocytopenia (HP:0001913)2.02456518
90Bruising susceptibility (HP:0000978)2.00876545
91Abnormality of the columella (HP:0009929)2.00170372
92Chronic mucocutaneous candidiasis (HP:0002728)1.99651517
93Recurrent cutaneous fungal infections (HP:0011370)1.99651517
94Abnormal number of erythroid precursors (HP:0012131)1.99301524
95Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.97154332
96Restrictive lung disease (HP:0002091)1.96983053
97Chronic obstructive pulmonary disease (HP:0006510)1.96828724
98Obstructive lung disease (HP:0006536)1.96828724
99Anhidrosis (HP:0000970)1.95623482
100Abnormality of the nasal septum (HP:0000419)1.95473100
101Abnormality of the prostate (HP:0008775)1.94680141
102Gastrointestinal stroma tumor (HP:0100723)1.94380182
103Hypergammaglobulinemia (HP:0010702)1.94237876
104Spondylolisthesis (HP:0003302)1.93696088
105Albinism (HP:0001022)1.93681602
106Ectopic kidney (HP:0000086)1.93083636
107Urticaria (HP:0001025)1.91018910
108Prostate neoplasm (HP:0100787)1.89928734
109Abnormality of the renal collecting system (HP:0004742)1.89893006
110Duplicated collecting system (HP:0000081)1.87994207
111Keratoconjunctivitis (HP:0001096)1.87985190
112Long eyelashes (HP:0000527)1.87466438
113Hepatitis (HP:0012115)1.87425829
114Amaurosis fugax (HP:0100576)1.86044969
115Abnormality of the phalanges of the hallux (HP:0010057)1.84495218
116Vasculitis (HP:0002633)1.83128798
117Abnormal delayed hypersensitivity skin test (HP:0002963)1.82248241
118Combined immunodeficiency (HP:0005387)1.80660658
119Abnormality of cells of the erythroid lineage (HP:0012130)1.78452031
120Deep philtrum (HP:0002002)1.76544238
121Epistaxis (HP:0000421)1.75941456
122Recurrent pneumonia (HP:0006532)1.75668257
123Chronic diarrhea (HP:0002028)1.74563757
124Aortic dissection (HP:0002647)1.73950850
125Volvulus (HP:0002580)1.73401479
126Aortic regurgitation (HP:0001659)1.73249591
127Bronchitis (HP:0012387)1.73220654
128Orchitis (HP:0100796)1.73054994
129Premature graying of hair (HP:0002216)1.72086188
130Abnormal platelet volume (HP:0011876)1.71630124
131Duplication of thumb phalanx (HP:0009942)1.71624080
132Recurrent gram-negative bacterial infections (HP:0005420)1.71565325
133Aortic valve stenosis (HP:0001650)1.68404853
134Birth length less than 3rd percentile (HP:0003561)1.68285899
135Supernumerary spleens (HP:0009799)1.67830671
136Long clavicles (HP:0000890)1.67522227
137Recurrent bacterial skin infections (HP:0005406)1.64960279
138Bone marrow hypocellularity (HP:0005528)1.63565631
139Abnormality of DNA repair (HP:0003254)1.62832053
140Hypoproteinemia (HP:0003075)1.62582817
141Recurrent sinusitis (HP:0011108)1.62107539
142Pulmonary fibrosis (HP:0002206)1.59767315
143Mediastinal lymphadenopathy (HP:0100721)1.58941146
144Abnormality of T cell physiology (HP:0011840)1.58034027
145Reduced antithrombin III activity (HP:0001976)1.57618494
146Gingival bleeding (HP:0000225)1.56784623

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK44.29764078
2TXK3.42233142
3MAP4K13.15827027
4PRPF4B3.07507804
5BMPR22.81372035
6RIPK42.57618852
7TEC2.30882104
8MKNK22.29375976
9RPS6KA42.23748245
10MAP3K142.23618333
11TRPM72.16103877
12KIT2.13795685
13MKNK11.91746908
14AKT31.89205219
15VRK11.83512490
16BLK1.83051190
17CAMKK21.78704682
18MAP3K131.75232833
19JAK31.72321126
20ZAK1.71328844
21MARK31.59020428
22EEF2K1.57585363
23BTK1.56002968
24NLK1.55602175
25IRAK31.51229083
26ITK1.45256961
27STK101.40080444
28CLK11.39841829
29FGFR31.39431332
30TNIK1.37133347
31CSK1.36374821
32SCYL21.34423873
33PIM11.32738596
34IKBKB1.32372204
35EIF2AK21.30593394
36TYK21.28060132
37IKBKE1.25572487
38STK41.24888930
39TLK11.23192950
40TGFBR21.22976263
41SYK1.20628181
42PIM21.19535695
43EPHA31.17275465
44CDK81.15451210
45JAK11.14044758
46ZAP701.13179812
47ERBB31.12960174
48GRK61.10528874
49CDK121.09304956
50BRD41.06373432
51FGR1.06246360
52LCK1.03539229
53JAK21.02242572
54YES11.01894127
55CHUK1.00784812
56HCK1.00054801
57BUB10.99394756
58ATR0.99181021
59TGFBR10.98626694
60EIF2AK30.98206758
61SRPK10.97622013
62GRK10.95920492
63LYN0.95390304
64CSF1R0.94823805
65RPS6KB20.93027017
66DYRK30.84429682
67SIK30.83209225
68CDC70.82768967
69IRAK10.82352347
70GRK70.81963448
71NUAK10.80524881
72NEK90.76731692
73NME20.75965337
74MAP2K20.75944612
75MATK0.75596551
76CDK70.74450109
77MAP3K20.73425777
78EPHB10.73074051
79SIK20.72758851
80PDGFRB0.72300843
81TBK10.72237984
82RPS6KA50.71544440
83MAP3K100.71011799
84SGK20.70684118
85CDK90.70530201
86MAP3K10.70383761
87NEK60.68816441
88MST40.67929062
89MAP2K30.67882259
90MAPKAPK30.67190572
91FGFR40.66493779
92TAOK30.66294246
93MAPK110.64681347
94PDK10.64304621
95HIPK20.60223779
96CAMKK10.59219577
97AURKB0.58609688
98CDK40.58342290
99MAPKAPK50.58298747
100MELK0.58238950
101SGK30.58105691
102FES0.57424794
103FLT30.56770032
104PIK3CG0.56121369
105LATS10.55333436
106CDK60.54746966
107STK240.54253835
108ATM0.54110880
109PASK0.52313728
110EGFR0.51280774
111RET0.51276606
112WNK10.51156205
113PRKCQ0.48810130
114BMPR1B0.47250075
115IRAK20.46342686
116STK30.44995926
117ABL10.44040452
118TNK20.43829345
119CHEK10.43550700
120PIK3CA0.43457874
121MAPKAPK20.43351022
122ACVR1B0.42605408
123PLK40.42492060
124MAPK70.42189404
125MAPK120.42149671
126BRSK20.41914639
127CDK30.39978205
128EIF2AK10.39778751
129MAP3K40.39423087
130TSSK60.39040561
131STK160.37701247
132KSR20.36067368
133CASK0.35928883
134MAPK30.35620175
135INSR0.33884765
136STK380.32813831
137IGF1R0.31307214
138DYRK1B0.30049297
139MAP3K50.29811338
140STK38L0.28559936
141RPS6KL10.25616318
142RPS6KC10.25616318
143MOS0.25528857

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.91689849
2Non-homologous end-joining_Homo sapiens_hsa034502.51894052
3DNA replication_Homo sapiens_hsa030302.36745797
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.24068910
5Hematopoietic cell lineage_Homo sapiens_hsa046402.17995971
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.12019990
7Homologous recombination_Homo sapiens_hsa034402.06343453
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.03111578
9Measles_Homo sapiens_hsa051621.96783549
10Mismatch repair_Homo sapiens_hsa034301.92428008
11Type I diabetes mellitus_Homo sapiens_hsa049401.85388920
12Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.84745124
13Leishmaniasis_Homo sapiens_hsa051401.84024344
14Base excision repair_Homo sapiens_hsa034101.70058681
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.66594259
16T cell receptor signaling pathway_Homo sapiens_hsa046601.58047512
17Transcriptional misregulation in cancer_Homo sapiens_hsa052021.57199516
18One carbon pool by folate_Homo sapiens_hsa006701.56044943
19Staphylococcus aureus infection_Homo sapiens_hsa051501.53677093
20Herpes simplex infection_Homo sapiens_hsa051681.52358148
21Ribosome_Homo sapiens_hsa030101.50208971
22Fanconi anemia pathway_Homo sapiens_hsa034601.47876521
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.45518943
24RNA degradation_Homo sapiens_hsa030181.44488500
25Cell cycle_Homo sapiens_hsa041101.41744368
26Nucleotide excision repair_Homo sapiens_hsa034201.40547038
27Osteoclast differentiation_Homo sapiens_hsa043801.38892579
28Basal transcription factors_Homo sapiens_hsa030221.38677982
29p53 signaling pathway_Homo sapiens_hsa041151.36474801
30Spliceosome_Homo sapiens_hsa030401.35034884
31B cell receptor signaling pathway_Homo sapiens_hsa046621.34691666
32Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.32223048
33Antigen processing and presentation_Homo sapiens_hsa046121.32158059
34Jak-STAT signaling pathway_Homo sapiens_hsa046301.30678355
35Allograft rejection_Homo sapiens_hsa053301.30429084
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.29082387
37Malaria_Homo sapiens_hsa051441.22772983
38Autoimmune thyroid disease_Homo sapiens_hsa053201.22675589
39Other glycan degradation_Homo sapiens_hsa005111.21237916
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.20861132
41RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.20066374
42Small cell lung cancer_Homo sapiens_hsa052221.12714610
43HTLV-I infection_Homo sapiens_hsa051661.12086599
44Hepatitis B_Homo sapiens_hsa051611.08986871
45Toll-like receptor signaling pathway_Homo sapiens_hsa046201.04438910
46TNF signaling pathway_Homo sapiens_hsa046681.03785726
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02776066
48Toxoplasmosis_Homo sapiens_hsa051451.02443964
49MicroRNAs in cancer_Homo sapiens_hsa052061.01670469
50Influenza A_Homo sapiens_hsa051641.00057796
51Renal cell carcinoma_Homo sapiens_hsa052110.98335463
52Viral carcinogenesis_Homo sapiens_hsa052030.98313200
53Inositol phosphate metabolism_Homo sapiens_hsa005620.98257692
54Legionellosis_Homo sapiens_hsa051340.97197197
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.96180069
56Pyrimidine metabolism_Homo sapiens_hsa002400.94765594
57Systemic lupus erythematosus_Homo sapiens_hsa053220.93665613
58RNA polymerase_Homo sapiens_hsa030200.92214221
59Pertussis_Homo sapiens_hsa051330.91024901
60Endometrial cancer_Homo sapiens_hsa052130.90702867
61Colorectal cancer_Homo sapiens_hsa052100.89448729
62Apoptosis_Homo sapiens_hsa042100.89333378
63Epstein-Barr virus infection_Homo sapiens_hsa051690.88791654
64Shigellosis_Homo sapiens_hsa051310.87146173
65Platelet activation_Homo sapiens_hsa046110.86773168
66Graft-versus-host disease_Homo sapiens_hsa053320.84567288
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.83117927
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82799564
69Acute myeloid leukemia_Homo sapiens_hsa052210.82324606
70ECM-receptor interaction_Homo sapiens_hsa045120.81403215
71Chronic myeloid leukemia_Homo sapiens_hsa052200.79972699
72Sphingolipid signaling pathway_Homo sapiens_hsa040710.78924419
73Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.78297993
74Thyroid cancer_Homo sapiens_hsa052160.77310510
75Asthma_Homo sapiens_hsa053100.76108467
76Sphingolipid metabolism_Homo sapiens_hsa006000.73930744
77RNA transport_Homo sapiens_hsa030130.73411775
78Viral myocarditis_Homo sapiens_hsa054160.73192983
79Phagosome_Homo sapiens_hsa041450.71926882
80Chemokine signaling pathway_Homo sapiens_hsa040620.70578607
81Choline metabolism in cancer_Homo sapiens_hsa052310.70564852
82Protein export_Homo sapiens_hsa030600.69634292
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69437256
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68539502
85Salmonella infection_Homo sapiens_hsa051320.65235402
86Tuberculosis_Homo sapiens_hsa051520.64999112
87Prostate cancer_Homo sapiens_hsa052150.64036949
88mTOR signaling pathway_Homo sapiens_hsa041500.63550104
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63098708
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62830782
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61751949
92Pathways in cancer_Homo sapiens_hsa052000.61655888
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61371551
94Glioma_Homo sapiens_hsa052140.61287084
95mRNA surveillance pathway_Homo sapiens_hsa030150.59846269
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.59674187
97Notch signaling pathway_Homo sapiens_hsa043300.59254787
98Pancreatic cancer_Homo sapiens_hsa052120.58323645
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57310494
100Hepatitis C_Homo sapiens_hsa051600.57030384
101Circadian rhythm_Homo sapiens_hsa047100.56676477
102Dorso-ventral axis formation_Homo sapiens_hsa043200.55483204
103TGF-beta signaling pathway_Homo sapiens_hsa043500.54404958
104VEGF signaling pathway_Homo sapiens_hsa043700.54187880
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.53028683
106Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52677850
107Amoebiasis_Homo sapiens_hsa051460.52398183
108Endocytosis_Homo sapiens_hsa041440.51034374
109ErbB signaling pathway_Homo sapiens_hsa040120.50506443
110Renin-angiotensin system_Homo sapiens_hsa046140.50125394
111Lysosome_Homo sapiens_hsa041420.49325990
112MAPK signaling pathway_Homo sapiens_hsa040100.48711286
113HIF-1 signaling pathway_Homo sapiens_hsa040660.48107755
114Insulin resistance_Homo sapiens_hsa049310.47676181
115Purine metabolism_Homo sapiens_hsa002300.47499655
116Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47320864
117Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46504219
118Long-term potentiation_Homo sapiens_hsa047200.46239039
119Rheumatoid arthritis_Homo sapiens_hsa053230.46121382
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45937644
121Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45861616
122SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45126770
123FoxO signaling pathway_Homo sapiens_hsa040680.44191012
124Prolactin signaling pathway_Homo sapiens_hsa049170.43894128
125Phospholipase D signaling pathway_Homo sapiens_hsa040720.43725125
126Focal adhesion_Homo sapiens_hsa045100.43494853
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43139361
128Non-small cell lung cancer_Homo sapiens_hsa052230.42967961
129Estrogen signaling pathway_Homo sapiens_hsa049150.42709748
130Proteoglycans in cancer_Homo sapiens_hsa052050.42023296
131Wnt signaling pathway_Homo sapiens_hsa043100.42008907
132GnRH signaling pathway_Homo sapiens_hsa049120.41938980
133Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41694890
134Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.40709290
135Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.38525410

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