YIPF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleotide transmembrane transport (GO:1901679)4.44798758
2fatty acid elongation (GO:0030497)4.28120613
3modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.21431788
4positive regulation by organism of defense response of other organism involved in symbiotic interact4.21431788
5modulation by symbiont of host immune response (GO:0052553)4.21431788
6positive regulation by symbiont of host defense response (GO:0052509)4.21431788
7modulation by symbiont of host defense response (GO:0052031)4.21431788
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.21431788
9signal peptide processing (GO:0006465)3.91576489
10protein complex biogenesis (GO:0070271)3.67399089
11mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.67237237
12mitochondrial respiratory chain complex I assembly (GO:0032981)3.67237237
13NADH dehydrogenase complex assembly (GO:0010257)3.67237237
14mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.64832474
15pyrimidine-containing compound transmembrane transport (GO:0072531)3.47566071
16respiratory chain complex IV assembly (GO:0008535)3.43145843
17response to peptidoglycan (GO:0032494)3.39950784
18central nervous system myelination (GO:0022010)3.35324433
19axon ensheathment in central nervous system (GO:0032291)3.35324433
20mannosylation (GO:0097502)3.32748847
21GPI anchor biosynthetic process (GO:0006506)3.29977544
22regulation of interferon-beta biosynthetic process (GO:0045357)3.29194001
23mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.25554679
24macrophage activation involved in immune response (GO:0002281)3.22810367
25aldehyde catabolic process (GO:0046185)3.22175306
26negative regulation of interleukin-12 production (GO:0032695)3.21647493
27immunoglobulin mediated immune response (GO:0016064)3.21472261
28mitochondrial respiratory chain complex assembly (GO:0033108)3.17790514
29artery smooth muscle contraction (GO:0014824)3.14417742
30ATP synthesis coupled proton transport (GO:0015986)3.12030931
31energy coupled proton transport, down electrochemical gradient (GO:0015985)3.12030931
32uronic acid metabolic process (GO:0006063)3.11844021
33glucuronate metabolic process (GO:0019585)3.11844021
34amyloid precursor protein catabolic process (GO:0042987)3.10164108
35cholesterol biosynthetic process (GO:0006695)3.09907096
36respiratory burst (GO:0045730)3.08155168
37L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.05917414
38respiratory electron transport chain (GO:0022904)3.02947076
39negative regulation of interleukin-1 production (GO:0032692)3.00938078
40electron transport chain (GO:0022900)2.99260890
41nucleotide transport (GO:0006862)2.97961414
42negative regulation of interleukin-1 beta production (GO:0032691)2.97800134
43cytochrome complex assembly (GO:0017004)2.97602941
44neutrophil activation (GO:0042119)2.97238973
45GPI anchor metabolic process (GO:0006505)2.95042656
46cellular glucuronidation (GO:0052695)2.92739936
47microglial cell activation (GO:0001774)2.91014903
48phagosome maturation (GO:0090382)2.90776827
49antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.88367080
50positive regulation of cellular amine metabolic process (GO:0033240)2.87737877
51long-chain fatty acid biosynthetic process (GO:0042759)2.87718477
52preassembly of GPI anchor in ER membrane (GO:0016254)2.87069866
53granulocyte activation (GO:0036230)2.86524118
54response to interferon-beta (GO:0035456)2.86209036
55positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.86171913
56B cell mediated immunity (GO:0019724)2.84221407
57negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.83168250
58detection of molecule of bacterial origin (GO:0032490)2.83130185
59purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.83064275
603-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.83064275
61regulation of metalloenzyme activity (GO:0048552)2.82837346
62amyloid precursor protein metabolic process (GO:0042982)2.80143496
63amino acid salvage (GO:0043102)2.79712245
64L-methionine salvage (GO:0071267)2.79712245
65L-methionine biosynthetic process (GO:0071265)2.79712245
66sterol biosynthetic process (GO:0016126)2.78208365
67GDP-mannose metabolic process (GO:0019673)2.77495212
68fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.75659636
69regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.74353445
70protein neddylation (GO:0045116)2.73935070
71response to redox state (GO:0051775)2.73403951
72positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.72931055
73superoxide anion generation (GO:0042554)2.72700980
74histamine secretion (GO:0001821)2.72176388
75positive regulation of interferon-alpha production (GO:0032727)2.72016507
76erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.71885698
77L-phenylalanine catabolic process (GO:0006559)2.71885698
78xenobiotic catabolic process (GO:0042178)2.69826216
79regulation of interferon-alpha production (GO:0032647)2.68065802
80cellular response to leptin stimulus (GO:0044320)2.66753184
81isoprenoid biosynthetic process (GO:0008299)2.66291854
82positive regulation of toll-like receptor signaling pathway (GO:0034123)2.63617523
83chaperone-mediated protein transport (GO:0072321)2.63234020
84positive regulation of monocyte chemotaxis (GO:0090026)2.62628468
85protein deneddylation (GO:0000338)2.59254431
86regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.57810879
87dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.56479839
88positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.55205305
89C-terminal protein lipidation (GO:0006501)2.55118606
90sequestering of actin monomers (GO:0042989)2.52209404
91tonic smooth muscle contraction (GO:0014820)2.50849218
92positive regulation of NF-kappaB import into nucleus (GO:0042346)2.50372717
93negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.48486586
94negative regulation of ligase activity (GO:0051352)2.48486586
95cullin deneddylation (GO:0010388)2.48075712
96negative regulation of cell killing (GO:0031342)2.46770939
97negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.46770939
98peptidyl-histidine modification (GO:0018202)2.45521004
99neutrophil mediated immunity (GO:0002446)2.45044830
100DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.44874488
101positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.44671673
102glyoxylate metabolic process (GO:0046487)2.43292068
103positive regulation of actin cytoskeleton reorganization (GO:2000251)2.42857009
104pantothenate metabolic process (GO:0015939)2.42743470
105regulation of interleukin-8 biosynthetic process (GO:0045414)2.42539095
106glutathione biosynthetic process (GO:0006750)2.42417840
107proteasome assembly (GO:0043248)2.42270926
108regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.42071032
109response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.41783621
110response to host immune response (GO:0052572)2.41783621
111detection of other organism (GO:0098543)2.41751471
112detection of external biotic stimulus (GO:0098581)2.40774398
113regulation of cilium movement (GO:0003352)2.39274923
114ATP hydrolysis coupled proton transport (GO:0015991)2.39142657
115energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.39142657
116carbohydrate derivative transport (GO:1901264)2.38914473
117nonribosomal peptide biosynthetic process (GO:0019184)2.37066641
118L-phenylalanine metabolic process (GO:0006558)2.36654351
119erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.36654351
120mitochondrial calcium ion homeostasis (GO:0051560)2.36176288
121sulfur amino acid catabolic process (GO:0000098)2.35659518
122ER overload response (GO:0006983)2.35178571
123tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.35127896
124RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.35127896
125antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.34634695
126signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.32937928
127signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.32937928
128signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.32937928
129signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.32357534
130intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.32357534
131myeloid leukocyte mediated immunity (GO:0002444)2.32007144
132regulation of cellular amine metabolic process (GO:0033238)2.31864542
133positive regulation of interleukin-17 production (GO:0032740)2.31327793
134regulation of regulatory T cell differentiation (GO:0045589)2.31087240
135interferon-gamma secretion (GO:0072643)2.30859333
136positive regulation of interferon-beta production (GO:0032728)2.30225578
137leukocyte migration involved in inflammatory response (GO:0002523)2.29563560
138myeloid cell activation involved in immune response (GO:0002275)2.29143689
139positive regulation of interleukin-10 production (GO:0032733)2.28787420
140vascular smooth muscle contraction (GO:0014829)2.28763250
141negative regulation of acute inflammatory response (GO:0002674)2.27460270
142sphingomyelin metabolic process (GO:0006684)2.25455532
143sphingoid metabolic process (GO:0046519)2.25142157
144water-soluble vitamin biosynthetic process (GO:0042364)2.25133286
145photoreceptor cell differentiation (GO:0046530)2.25015077
146eye photoreceptor cell differentiation (GO:0001754)2.25015077
147cofactor catabolic process (GO:0051187)2.24970771
148regulation of cytokine secretion involved in immune response (GO:0002739)2.24847057
149nucleotide-sugar biosynthetic process (GO:0009226)2.24538990
150hydrogen peroxide catabolic process (GO:0042744)2.24427947
151detection of bacterium (GO:0016045)2.24089328
152phagocytosis, engulfment (GO:0006911)2.24061388
153cellular response to interferon-beta (GO:0035458)2.23797251
154very long-chain fatty acid metabolic process (GO:0000038)2.23208500
155leukocyte aggregation (GO:0070486)2.23114489
156antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.21976037
157positive regulation of T cell mediated cytotoxicity (GO:0001916)2.21279803
158termination of RNA polymerase III transcription (GO:0006386)2.21076106
159transcription elongation from RNA polymerase III promoter (GO:0006385)2.21076106
160regulation of cellular amino acid metabolic process (GO:0006521)2.20748395
161negative regulation of nitric oxide biosynthetic process (GO:0045019)2.20238656
162negative regulation of transcription by competitive promoter binding (GO:0010944)2.20148564
163neutrophil activation involved in immune response (GO:0002283)2.19708968
164glutathione derivative metabolic process (GO:1901685)2.18936020
165glutathione derivative biosynthetic process (GO:1901687)2.18936020
166negative regulation of chemokine production (GO:0032682)2.18803658
167aromatic amino acid family catabolic process (GO:0009074)2.18685514
168purine ribonucleotide transport (GO:0015868)2.18344089
169opsonization (GO:0008228)2.17864518
170C-terminal protein amino acid modification (GO:0018410)2.15747090
171negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.15292598
172intracellular pH reduction (GO:0051452)2.15044789
173glutathione metabolic process (GO:0006749)2.14072218
174antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.13945699
175ribosomal small subunit assembly (GO:0000028)2.13433331
176regulation of antigen processing and presentation (GO:0002577)2.13277600
177aerobic respiration (GO:0009060)2.13190540
178negative regulation of execution phase of apoptosis (GO:1900118)2.12912915
179pH reduction (GO:0045851)2.12690159
180detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)2.11498636
181proton transport (GO:0015992)2.11470441
182fucose metabolic process (GO:0006004)2.11227619
183sulfation (GO:0051923)2.10483501
184nucleotide-sugar metabolic process (GO:0009225)2.09417874

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.44933073
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.26923247
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.76993345
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.64078691
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.63623670
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.62257027
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.50627858
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.46036133
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.43873384
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.37957119
11SPI1_23547873_ChIP-Seq_NB4_Human2.23450760
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.22964832
13IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.21658683
14PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.20268371
15CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.08582617
16IRF8_21731497_ChIP-ChIP_J774_Mouse2.05917583
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.04501965
18ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.01097591
19CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.98069306
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.91690470
21LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.87093623
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.86866876
23VDR_23849224_ChIP-Seq_CD4+_Human1.83454203
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.80060751
25EST1_17652178_ChIP-ChIP_JURKAT_Human1.80044791
26MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.78166289
27* FOXP3_21729870_ChIP-Seq_TREG_Human1.70313144
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.64997278
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.64018486
30ELK1_19687146_ChIP-ChIP_HELA_Human1.63718445
31TAF15_26573619_Chip-Seq_HEK293_Human1.61896577
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.61621062
33HTT_18923047_ChIP-ChIP_STHdh_Human1.61074970
34SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.60620624
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56002265
36GBX2_23144817_ChIP-Seq_PC3_Human1.54552664
37VDR_22108803_ChIP-Seq_LS180_Human1.54315789
38NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.52491657
39PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.52260000
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50280381
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.48681170
42TFEB_21752829_ChIP-Seq_HELA_Human1.45823207
43RXR_22158963_ChIP-Seq_LIVER_Mouse1.45508994
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.42848462
45FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.40668054
46CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.40555734
47* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.38650279
48CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.34511114
49GABP_19822575_ChIP-Seq_HepG2_Human1.34263279
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.32127910
51HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.30307306
52* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.29819142
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.28455549
54PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27757056
55STAT4_19710469_ChIP-ChIP_TH1__Mouse1.25357349
56FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.22543470
57STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.22257970
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.20479517
59KAP1_22055183_ChIP-Seq_ESCs_Mouse1.19420551
60KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.19172393
61KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.19172393
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.19172393
63SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19083446
64EZH2_27294783_Chip-Seq_NPCs_Mouse1.16377789
65CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15140462
66MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.14918536
67SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13507429
68RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11950779
69MYB_21317192_ChIP-Seq_ERMYB_Mouse1.11878842
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11139357
71* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.10803474
72* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.10796706
73DCP1A_22483619_ChIP-Seq_HELA_Human1.10728860
74IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10484133
75ELK1_22589737_ChIP-Seq_MCF10A_Human1.10282061
76NFE2_27457419_Chip-Seq_LIVER_Mouse1.09723196
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.09248988
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.08092999
79STAT3_18555785_Chip-Seq_ESCs_Mouse1.08073750
80ETS1_20019798_ChIP-Seq_JURKAT_Human1.07809189
81BP1_19119308_ChIP-ChIP_Hs578T_Human1.07498374
82NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.07071547
83SOX2_20726797_ChIP-Seq_SW620_Human1.07014712
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06994274
85CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06354429
86AR_20517297_ChIP-Seq_VCAP_Human1.05906534
87ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05185886
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.04860500
89BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.04716272
90ER_23166858_ChIP-Seq_MCF-7_Human1.04216917
91* EOMES_21245162_ChIP-Seq_HESCs_Human1.03500313
92CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03482514
93CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03358364
94CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.03206220
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.03173476
96PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.02618486
97* PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02351279
98GATA3_26560356_Chip-Seq_TH2_Human1.01233682
99SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01018605
100IGF1R_20145208_ChIP-Seq_DFB_Human1.00868350
101RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00549179
102TAL1_26923725_Chip-Seq_HPCs_Mouse0.99698697
103ELF5_23300383_ChIP-Seq_T47D_Human0.98882942
104SMAD1_18555785_Chip-Seq_ESCs_Mouse0.98469411
105CRX_20693478_ChIP-Seq_RETINA_Mouse0.97832064
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97054281
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97054281
108FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95986672
109LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95621776
110Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.95424396
111RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95245243
112PPARA_22158963_ChIP-Seq_LIVER_Mouse0.94918688
113SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94906707
114FOXA1_21572438_ChIP-Seq_LNCaP_Human0.94073719
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92542588
116SMAD_19615063_ChIP-ChIP_OVARY_Human0.92282371
117TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.92192947
118PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.91893362
119ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91779458
120SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.90721033
121ETV2_25802403_ChIP-Seq_MESCs_Mouse0.90670926
122STAT1_20625510_ChIP-Seq_HELA_Human0.90632826
123LXR_22158963_ChIP-Seq_LIVER_Mouse0.90554827
124EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90343611
125BRD4_27068464_Chip-Seq_AML-cells_Mouse0.90187334
126ERG_20517297_ChIP-Seq_VCAP_Human0.90067284
127NANOG_19829295_ChIP-Seq_ESCs_Human0.90039349
128SOX2_19829295_ChIP-Seq_ESCs_Human0.90039349
129NANOG_18555785_Chip-Seq_ESCs_Mouse0.89953979
130NELFA_20434984_ChIP-Seq_ESCs_Mouse0.89674489
131MYB_26560356_Chip-Seq_TH2_Human0.89114499
132P53_22387025_ChIP-Seq_ESCs_Mouse0.89017344
133SALL4_22934838_ChIP-ChIP_CD34+_Human0.88987619
134CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88893913
135EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88865039
136P300_18555785_Chip-Seq_ESCs_Mouse0.88862750
137NMYC_18555785_Chip-Seq_ESCs_Mouse0.88712205
138P300_19829295_ChIP-Seq_ESCs_Human0.88605959
139MYC_18358816_ChIP-ChIP_MESCs_Mouse0.87911389
140PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87790529
141PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87622538
142* IRF8_27001747_Chip-Seq_BMDM_Mouse0.87408118
143THAP11_20581084_ChIP-Seq_MESCs_Mouse0.87094140
144AR_21572438_ChIP-Seq_LNCaP_Human0.86404337
145CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.86050119
146SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.85430998
147IKZF1_21737484_ChIP-ChIP_HCT116_Human0.84864576
148* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.84519018
149SPI1_23127762_ChIP-Seq_K562_Human0.84078862
150KLF4_18555785_Chip-Seq_ESCs_Mouse0.84049886
151HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.84009810
152TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.83650085
153TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.82172931

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001986_abnormal_taste_sensitivity3.34433294
2MP0008875_abnormal_xenobiotic_pharmacok2.54468680
3MP0002876_abnormal_thyroid_physiology2.54200550
4MP0009379_abnormal_foot_pigmentation2.42008387
5MP0001835_abnormal_antigen_presentation2.38820902
6MP0002139_abnormal_hepatobiliary_system2.34933899
7MP0005360_urolithiasis2.28616581
8MP0003303_peritoneal_inflammation2.26117855
9MP0009785_altered_susceptibility_to2.22494314
10MP0003195_calcinosis2.18188648
11MP0003724_increased_susceptibility_to2.12273596
12MP0001905_abnormal_dopamine_level2.07910106
13MP0005451_abnormal_body_composition2.02892818
14MP0002822_catalepsy1.98569835
15MP0002148_abnormal_hypersensitivity_rea1.94196791
16MP0006082_CNS_inflammation1.92349889
17MP0003806_abnormal_nucleotide_metabolis1.89456810
18MP0005085_abnormal_gallbladder_physiolo1.88298425
19MP0005671_abnormal_response_to1.83046710
20MP0009278_abnormal_bone_marrow1.82627274
21MP0008260_abnormal_autophagy1.81103938
22MP0001666_abnormal_nutrient_absorption1.77826483
23MP0000685_abnormal_immune_system1.76135403
24MP0005310_abnormal_salivary_gland1.75714520
25MP0001529_abnormal_vocalization1.70784673
26MP0004134_abnormal_chest_morphology1.70178175
27MP0001542_abnormal_bone_strength1.69635287
28MP0000343_altered_response_to1.65215533
29MP0003186_abnormal_redox_activity1.65053930
30MP0005365_abnormal_bile_salt1.62425898
31MP0010386_abnormal_urinary_bladder1.61327898
32MP0002132_abnormal_respiratory_system1.60036316
33MP0005058_abnormal_lysosome_morphology1.59474322
34MP0000920_abnormal_myelination1.54342949
35MP0001873_stomach_inflammation1.54053569
36MP0005025_abnormal_response_to1.53863697
37MP0004147_increased_porphyrin_level1.50377272
38MP0005000_abnormal_immune_tolerance1.48178123
39MP0002933_joint_inflammation1.46488459
40MP0005387_immune_system_phenotype1.45611972
41MP0001790_abnormal_immune_system1.45611972
42MP0005645_abnormal_hypothalamus_physiol1.44722438
43MP0001764_abnormal_homeostasis1.44576433
44MP0004381_abnormal_hair_follicle1.43711579
45MP0003868_abnormal_feces_composition1.43124848
46MP0002419_abnormal_innate_immunity1.40614830
47MP0003172_abnormal_lysosome_physiology1.33337234
48MP0004019_abnormal_vitamin_homeostasis1.32107723
49MP0005379_endocrine/exocrine_gland_phen1.31875801
50MP0004043_abnormal_pH_regulation1.30885925
51MP0002138_abnormal_hepatobiliary_system1.30707909
52MP0003866_abnormal_defecation1.30025198
53MP0003436_decreased_susceptibility_to1.28846160
54MP0002090_abnormal_vision1.27255223
55MP0003191_abnormal_cellular_cholesterol1.26516996
56MP0005332_abnormal_amino_acid1.25979906
57MP0005166_decreased_susceptibility_to1.25437617
58MP0005636_abnormal_mineral_homeostasis1.23330847
59MP0001663_abnormal_digestive_system1.22892803
60MP0002277_abnormal_respiratory_mucosa1.22719137
61MP0006035_abnormal_mitochondrial_morpho1.21588180
62MP0002723_abnormal_immune_serum1.20647897
63MP0000465_gastrointestinal_hemorrhage1.19653736
64MP0005381_digestive/alimentary_phenotyp1.19001998
65MP0003300_gastrointestinal_ulcer1.18581571
66MP0001800_abnormal_humoral_immune1.18299525
67MP0009840_abnormal_foam_cell1.15747403
68MP0003075_altered_response_to1.15710647
69MP0003183_abnormal_peptide_metabolism1.15354482
70MP0004142_abnormal_muscle_tone1.13785954
71MP0004883_abnormal_blood_vessel1.13249840
72MP0009765_abnormal_xenobiotic_induced1.12899134
73MP0005464_abnormal_platelet_physiology1.12405181
74MP0002452_abnormal_antigen_presenting1.12124301
75MP0009697_abnormal_copulation1.11305035
76MP0008469_abnormal_protein_level1.10680564
77MP0005084_abnormal_gallbladder_morpholo1.10474400
78MP0001188_hyperpigmentation1.08989622
79MP0002163_abnormal_gland_morphology1.08508993
80MP0003136_yellow_coat_color1.08384464
81MP0001664_abnormal_digestion1.08056085
82MP0003828_pulmonary_edema1.07672087
83MP0000604_amyloidosis1.06766421
84MP0008789_abnormal_olfactory_epithelium1.06747648
85MP0000858_altered_metastatic_potential1.06453126
86MP0002254_reproductive_system_inflammat1.06247607
87MP0004742_abnormal_vestibular_system1.05748014
88MP0004782_abnormal_surfactant_physiolog1.05304997
89MP0009643_abnormal_urine_homeostasis1.04181536
90MP0001853_heart_inflammation1.03712472
91MP0003690_abnormal_glial_cell1.03078358
92MP0002420_abnormal_adaptive_immunity1.02614694
93MP0001533_abnormal_skeleton_physiology1.02404217
94MP0009384_cardiac_valve_regurgitation1.01886187
95MP0001819_abnormal_immune_cell1.01771946
96MP0001984_abnormal_olfaction1.01001516
97MP0005394_taste/olfaction_phenotype1.00815394
98MP0005499_abnormal_olfactory_system1.00815394
99MP0010155_abnormal_intestine_physiology0.99836333
100MP0001845_abnormal_inflammatory_respons0.99306093
101MP0003011_delayed_dark_adaptation0.99197536
102MP0003656_abnormal_erythrocyte_physiolo0.98159767
103MP0003329_amyloid_beta_deposits0.96166394
104MP0005075_abnormal_melanosome_morpholog0.95601399
105MP0005408_hypopigmentation0.95225840
106MP0005319_abnormal_enzyme/_coenzyme0.95004208
107MP0008004_abnormal_stomach_pH0.94908896
108MP0000372_irregular_coat_pigmentation0.94642034
109MP0005377_hearing/vestibular/ear_phenot0.93419955
110MP0003878_abnormal_ear_physiology0.93419955
111MP0004947_skin_inflammation0.91843800
112MP0005164_abnormal_response_to0.91382067
113MP0004264_abnormal_extraembryonic_tissu0.90359145
114MP0009763_increased_sensitivity_to0.89653645
115MP0000716_abnormal_immune_system0.88111310
116MP0005551_abnormal_eye_electrophysiolog0.87361599
117MP0002166_altered_tumor_susceptibility0.86928285
118MP0000462_abnormal_digestive_system0.86462606
119MP0002405_respiratory_system_inflammati0.86421126
120MP0009333_abnormal_splenocyte_physiolog0.85774689
121MP0005083_abnormal_biliary_tract0.85096624
122MP0001346_abnormal_lacrimal_gland0.84840955
123MP0005584_abnormal_enzyme/coenzyme_acti0.84715798
124MP0005220_abnormal_exocrine_pancreas0.84497356
125MP0003448_altered_tumor_morphology0.83961838
126MP0001727_abnormal_embryo_implantation0.83900758
127MP0006036_abnormal_mitochondrial_physio0.83351063
128MP0000609_abnormal_liver_physiology0.82969447
129MP0009764_decreased_sensitivity_to0.82139755
130MP0000490_abnormal_crypts_of0.80751805
131MP0002653_abnormal_ependyma_morphology0.78559944
132MP0000358_abnormal_cell_content/0.77612160
133MP0003221_abnormal_cardiomyocyte_apopto0.73457374
134MP0005397_hematopoietic_system_phenotyp0.73013251

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of macrophages (HP:0004311)3.94332983
2Acute necrotizing encephalopathy (HP:0006965)3.76877549
3Elevated erythrocyte sedimentation rate (HP:0003565)3.76745047
4Mitochondrial inheritance (HP:0001427)3.50317941
5Myositis (HP:0100614)3.46638056
6Abnormal mitochondria in muscle tissue (HP:0008316)3.42838277
7Hepatocellular necrosis (HP:0001404)3.42833711
8Recurrent gram-negative bacterial infections (HP:0005420)3.36868981
9Irregular epiphyses (HP:0010582)3.35432001
10Loss of speech (HP:0002371)3.34273718
11Acute encephalopathy (HP:0006846)3.24748530
123-Methylglutaconic aciduria (HP:0003535)3.21337146
13Hepatic necrosis (HP:0002605)3.20400992
14Abnormal tarsal ossification (HP:0008369)3.07785491
15Spontaneous hematomas (HP:0007420)3.06491231
16Orchitis (HP:0100796)3.01900003
17Renal Fanconi syndrome (HP:0001994)3.00877377
18Abnormality of liposaccharide metabolism (HP:0010968)2.98242945
19Abnormality of glycosphingolipid metabolism (HP:0004343)2.98242945
20Abnormality of glycolipid metabolism (HP:0010969)2.98242945
21Progressive macrocephaly (HP:0004481)2.94031637
22Optic neuritis (HP:0100653)2.89260845
23Retrobulbar optic neuritis (HP:0100654)2.89260845
24Increased CSF lactate (HP:0002490)2.88922195
25Abnormality of aromatic amino acid family metabolism (HP:0004338)2.84443008
26Parakeratosis (HP:0001036)2.80065113
27Epiphyseal dysplasia (HP:0002656)2.73340633
28Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.73193692
29Episodic fever (HP:0001954)2.67354821
30Type I transferrin isoform profile (HP:0003642)2.64838177
31Small epiphyses (HP:0010585)2.64539513
32Increased hepatocellular lipid droplets (HP:0006565)2.63304615
33Systemic lupus erythematosus (HP:0002725)2.63130855
34Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.56591291
35Reduced antithrombin III activity (HP:0001976)2.50974423
36Delayed epiphyseal ossification (HP:0002663)2.48871622
37Lipid accumulation in hepatocytes (HP:0006561)2.48793993
38Vacuolated lymphocytes (HP:0001922)2.48119730
39Beaking of vertebral bodies (HP:0004568)2.43425742
40Mutism (HP:0002300)2.42382819
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.42006559
42Flat capital femoral epiphysis (HP:0003370)2.38157403
43Cerebral edema (HP:0002181)2.37284937
44Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.36890564
45Hypothermia (HP:0002045)2.35204473
46Prolonged partial thromboplastin time (HP:0003645)2.30649236
47Obstructive lung disease (HP:0006536)2.29103722
48Chronic obstructive pulmonary disease (HP:0006510)2.29103722
49Metaphyseal irregularity (HP:0003025)2.27940198
50Abnormal protein N-linked glycosylation (HP:0012347)2.27933921
51Abnormal protein glycosylation (HP:0012346)2.27933921
52Abnormal glycosylation (HP:0012345)2.27933921
53Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27933921
54Decreased activity of mitochondrial respiratory chain (HP:0008972)2.23488940
55Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.23488940
56Abnormality of glycolysis (HP:0004366)2.22711653
57Increased serum pyruvate (HP:0003542)2.22711653
58Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.20124794
59Anorexia (HP:0002039)2.18805738
60Polyphagia (HP:0002591)2.17979372
61Abnormality of renal resorption (HP:0011038)2.16171596
62Purpura (HP:0000979)2.15616804
63Increased serum lactate (HP:0002151)2.12825374
64Encephalitis (HP:0002383)2.12706916
65Cupped ribs (HP:0000887)2.12578554
66Lactic acidosis (HP:0003128)2.12484088
67Increased intramyocellular lipid droplets (HP:0012240)2.11904968
68Respiratory failure (HP:0002878)2.11687880
69Abnormality of the vertebral endplates (HP:0005106)2.11538169
70Petechiae (HP:0000967)2.10423270
71Optic disc pallor (HP:0000543)2.10187501
72Short femoral neck (HP:0100864)2.10158508
73Steatorrhea (HP:0002570)2.09758204
74Leukodystrophy (HP:0002415)2.08059575
75Amyloidosis (HP:0011034)2.07173794
76Microretrognathia (HP:0000308)2.06663905
77Prolonged neonatal jaundice (HP:0006579)2.05169776
78Exertional dyspnea (HP:0002875)2.05134470
79Genu varum (HP:0002970)2.04310504
80Congenital ichthyosiform erythroderma (HP:0007431)2.04177725
81Abolished electroretinogram (ERG) (HP:0000550)2.03147814
82Urticaria (HP:0001025)2.01920872
83Fat malabsorption (HP:0002630)2.01110844
84Generalized aminoaciduria (HP:0002909)1.99531341
85Congenital primary aphakia (HP:0007707)1.99362588
86Gait imbalance (HP:0002141)1.98424879
87CNS demyelination (HP:0007305)1.96142587
88Increased cerebral lipofuscin (HP:0011813)1.95959697
89Irregular vertebral endplates (HP:0003301)1.95429252
90Medial flaring of the eyebrow (HP:0010747)1.94961449
91Abnormality of the femoral head (HP:0003368)1.94880064
92Vaginal fistula (HP:0004320)1.94455784
93Aplasia/hypoplasia of the uterus (HP:0008684)1.94408982
94Abnormal respiratory motile cilium morphology (HP:0005938)1.92716384
95Abnormal respiratory epithelium morphology (HP:0012253)1.92716384
96Sensorimotor neuropathy (HP:0007141)1.90737577
97Abnormality of urine glucose concentration (HP:0011016)1.90022482
98Glycosuria (HP:0003076)1.90022482
99Abnormal foot bone ossification (HP:0010675)1.89127796
100Rectal fistula (HP:0100590)1.89015537
101Rectovaginal fistula (HP:0000143)1.89015537
102Thyroid-stimulating hormone excess (HP:0002925)1.88605512
103Intrahepatic cholestasis (HP:0001406)1.87764641
104Conjugated hyperbilirubinemia (HP:0002908)1.87681647
105Abnormality of monocarboxylic acid metabolism (HP:0010996)1.86752424
106Disinhibition (HP:0000734)1.86659225
107Abnormality of carpal bone ossification (HP:0006257)1.86511618
108Recurrent bacterial skin infections (HP:0005406)1.86210354
109Mediastinal lymphadenopathy (HP:0100721)1.85270652
110Hepatosplenomegaly (HP:0001433)1.85221475
111Hyperammonemia (HP:0001987)1.85070700
112Recurrent abscess formation (HP:0002722)1.84805414
113Increased muscle lipid content (HP:0009058)1.84784751
114Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.84518829
115Abnormality of alanine metabolism (HP:0010916)1.84518829
116Hyperalaninemia (HP:0003348)1.84518829
117Hypoplasia of the uterus (HP:0000013)1.84501808
118Lethargy (HP:0001254)1.83733483
119Microvesicular hepatic steatosis (HP:0001414)1.83458892
120Hypochromic microcytic anemia (HP:0004840)1.83341792
121Delayed CNS myelination (HP:0002188)1.83267162
122Increased IgM level (HP:0003496)1.82702433
123Stenosis of the external auditory canal (HP:0000402)1.81176339
124Recurrent skin infections (HP:0001581)1.80491700
125Short tibia (HP:0005736)1.80402632
126Hypobetalipoproteinemia (HP:0003563)1.79294308
127Exercise intolerance (HP:0003546)1.79291794
128Pancreatitis (HP:0001733)1.78658078
129Abnormality of the epiphysis of the femoral head (HP:0010574)1.78310810
130Hematochezia (HP:0002573)1.78039336
131Irritability (HP:0000737)1.76238416
132Autoamputation (HP:0001218)1.75713432
133Flattened epiphyses (HP:0003071)1.75593812
134IgM deficiency (HP:0002850)1.70853313
135Eczematoid dermatitis (HP:0000976)1.70684197
136Barrel-shaped chest (HP:0001552)1.69687159
137Increased neuronal autofluorescent lipopigment (HP:0002074)1.69512427
138Aplasia/Hypoplasia of the tibia (HP:0005772)1.69382063
139Abnormality of serum amino acid levels (HP:0003112)1.68942470
140Microcytic anemia (HP:0001935)1.68374116
141Abnormality of femoral epiphyses (HP:0006499)1.68238721
142Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.68238721
143Disproportionate short-trunk short stature (HP:0003521)1.67008403
144Abnormality of fatty-acid metabolism (HP:0004359)1.66979889
145Hypergammaglobulinemia (HP:0010702)1.66882905
146Progressive neurologic deterioration (HP:0002344)1.66209865
147Ovoid vertebral bodies (HP:0003300)1.65696175
148Patchy hypopigmentation of hair (HP:0011365)1.65647802
149Hypokinesia (HP:0002375)1.65340788
150Spastic paraparesis (HP:0002313)1.64827469
151Pulmonary embolism (HP:0002204)1.64711341
152Vasculitis (HP:0002633)1.64142606
153Abnormal ciliary motility (HP:0012262)1.63757582
154Stomatitis (HP:0010280)1.63346151
155Hyperphosphaturia (HP:0003109)1.60164266
156Abnormality of the intrinsic pathway (HP:0010989)1.60049769
157Nephrogenic diabetes insipidus (HP:0009806)1.59769138
158Recurrent pneumonia (HP:0006532)1.59697049
159Congenital stationary night blindness (HP:0007642)1.59541213
160Abnormal pupillary function (HP:0007686)1.58600281
161Cerebral palsy (HP:0100021)1.58261516

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM283.29035941
2MST43.16864557
3STK162.99310297
4PIM22.56346318
5STK392.43991404
6CASK2.41617370
7MAP3K112.30170261
8TNIK2.14411409
9OXSR12.10119814
10ARAF2.09767907
11NME12.08594425
12TESK12.05151986
13IRAK42.01724729
14NME22.01240553
15PBK1.94742988
16ADRBK21.83481433
17TXK1.80784807
18MAP3K121.76849578
19BLK1.75697898
20MAP3K141.74502093
21BMPR21.67794824
22MYLK1.58735300
23EPHB11.57580983
24MUSK1.55231881
25EIF2AK31.53813404
26ERN11.52474195
27GRK61.51941724
28GRK11.51709086
29MAP2K31.49581827
30IRAK31.48781988
31DYRK31.46510867
32NLK1.39041502
33TIE11.37979705
34MAP3K61.37474974
35MAP3K51.32183216
36MAPK151.30978793
37BMPR1B1.30012464
38EIF2AK11.27973751
39BCKDK1.25640702
40VRK11.25056625
41RIPK41.23166712
42TEC1.22578884
43CDK191.21543813
44TESK21.19811161
45PAK41.17434679
46BRAF1.15883571
47MAPKAPK31.12923849
48TYK21.12555814
49MAPKAPK51.11738532
50ERBB31.11404350
51BUB11.10975821
52MST1R1.09418340
53WNK41.07084493
54MAP2K41.05770625
55TAOK31.05725673
56BCR1.05557813
57NUAK11.04461163
58DAPK11.04111888
59PIK3CG1.03879211
60KIT1.03100559
61IKBKE1.02031994
62ACVR1B1.01154225
63PINK10.99541014
64IRAK10.99061208
65INSRR0.95827103
66NEK60.94269265
67SRPK10.92156028
68IKBKB0.91913853
69DYRK20.90846985
70CSNK1G30.88510118
71FER0.88097823
72TGFBR20.87936439
73EIF2AK20.84576632
74SYK0.83649468
75ZAK0.82599099
76CDK30.80209890
77KSR10.80183716
78LRRK20.80068548
79MAP4K10.79680967
80CCNB10.79249595
81BTK0.79208171
82MAP2K70.76814051
83LYN0.76735486
84FES0.76396562
85MAP2K20.75479384
86YES10.74828121
87ZAP700.74566031
88LIMK10.74538722
89STK100.74452647
90PRKCE0.74278509
91CAMK2B0.73336788
92TBK10.73179479
93GRK70.72858491
94PRKCQ0.72240849
95VRK20.70430071
96RPS6KA50.69285085
97WNK30.68662517
98CDK80.68585005
99CSNK1G20.68254524
100FGR0.67799634
101CAMK2G0.67461118
102CSNK1G10.65573454
103TAOK10.64810923
104ABL20.64492885
105CAMK2D0.63991560
106LCK0.62656267
107STK240.62398863
108PRKG20.61688377
109IRAK20.61479002
110CSF1R0.60932234
111AKT30.60135484
112PKN10.59435252
113JAK20.59165293
114MAP3K30.58530523
115ERBB40.58471544
116SIK30.57406142
117PDK20.56296969
118MAPKAPK20.54461808
119GRK50.53919067
120EPHA30.53572784
121MAP3K10.53081238
122MATK0.53055930
123TNK20.52721241
124HCK0.52235527
125MKNK10.52161719
126MAP2K60.52014437
127MINK10.51030032
128PRKCI0.50681956
129JAK10.50482138
130CSNK1A1L0.49004779
131MET0.48597271
132CSK0.48134069
133MAPK40.47018231
134MAP3K40.46931325
135PRKCD0.46748365
136MKNK20.45664252
137ITK0.44254403
138JAK30.43952055
139MAP4K20.41937850
140ALK0.41830592

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.58848795
2Sulfur metabolism_Homo sapiens_hsa009203.38996982
3Oxidative phosphorylation_Homo sapiens_hsa001903.19548301
4Fatty acid elongation_Homo sapiens_hsa000622.61136768
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.44621819
6Parkinsons disease_Homo sapiens_hsa050122.33179778
7Proteasome_Homo sapiens_hsa030502.23522611
8Steroid biosynthesis_Homo sapiens_hsa001002.17425543
9Histidine metabolism_Homo sapiens_hsa003402.16118089
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96614181
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.91816941
12Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.88302820
13Folate biosynthesis_Homo sapiens_hsa007901.84903598
14Alzheimers disease_Homo sapiens_hsa050101.83921591
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.76970971
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.71171743
17Ribosome_Homo sapiens_hsa030101.70822529
18Pentose and glucuronate interconversions_Homo sapiens_hsa000401.69449281
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.68181785
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.62843783
21Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.60115922
22Chemical carcinogenesis_Homo sapiens_hsa052041.52583055
23Sphingolipid metabolism_Homo sapiens_hsa006001.49936487
24Legionellosis_Homo sapiens_hsa051341.49183256
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.45254721
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.43862317
27Huntingtons disease_Homo sapiens_hsa050161.43166760
28RNA polymerase_Homo sapiens_hsa030201.41376444
29Ether lipid metabolism_Homo sapiens_hsa005651.38105865
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.36989577
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.35202043
32Arachidonic acid metabolism_Homo sapiens_hsa005901.34777307
33Peroxisome_Homo sapiens_hsa041461.34738217
34Sulfur relay system_Homo sapiens_hsa041221.31529655
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.30731574
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.29975075
37Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.29371054
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.28942521
39Other glycan degradation_Homo sapiens_hsa005111.28550928
40Glutathione metabolism_Homo sapiens_hsa004801.26004279
41Collecting duct acid secretion_Homo sapiens_hsa049661.23618702
42Intestinal immune network for IgA production_Homo sapiens_hsa046721.21388501
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.20606814
44Retinol metabolism_Homo sapiens_hsa008301.19580104
45Rheumatoid arthritis_Homo sapiens_hsa053231.17360225
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.16957341
47Linoleic acid metabolism_Homo sapiens_hsa005911.14937894
48Tuberculosis_Homo sapiens_hsa051521.13734158
49Butanoate metabolism_Homo sapiens_hsa006501.12483384
50NOD-like receptor signaling pathway_Homo sapiens_hsa046211.12436279
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12019027
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.11505246
53Graft-versus-host disease_Homo sapiens_hsa053321.10920311
54Salmonella infection_Homo sapiens_hsa051321.10258054
55Primary immunodeficiency_Homo sapiens_hsa053401.09365633
56Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.08282349
57Vitamin B6 metabolism_Homo sapiens_hsa007501.07272903
58Phototransduction_Homo sapiens_hsa047441.06843923
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.06424170
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.06367333
61Galactose metabolism_Homo sapiens_hsa000521.04227448
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03101007
63Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03093677
64Arginine and proline metabolism_Homo sapiens_hsa003301.02107241
65Leishmaniasis_Homo sapiens_hsa051401.00888785
66Regulation of autophagy_Homo sapiens_hsa041400.99872217
67beta-Alanine metabolism_Homo sapiens_hsa004100.98725954
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96886449
69Osteoclast differentiation_Homo sapiens_hsa043800.96121345
70Metabolic pathways_Homo sapiens_hsa011000.95828181
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.95389084
72Phenylalanine metabolism_Homo sapiens_hsa003600.94120278
73Shigellosis_Homo sapiens_hsa051310.93929461
74Vitamin digestion and absorption_Homo sapiens_hsa049770.93447342
75Vibrio cholerae infection_Homo sapiens_hsa051100.93411096
76Drug metabolism - other enzymes_Homo sapiens_hsa009830.92137019
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90441868
78Allograft rejection_Homo sapiens_hsa053300.90334430
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.89589216
80Pertussis_Homo sapiens_hsa051330.86438267
81Tyrosine metabolism_Homo sapiens_hsa003500.85781887
82Tryptophan metabolism_Homo sapiens_hsa003800.79047545
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.77674754
84Pyruvate metabolism_Homo sapiens_hsa006200.77517030
85Pyrimidine metabolism_Homo sapiens_hsa002400.76829945
86Staphylococcus aureus infection_Homo sapiens_hsa051500.73734060
87Lysosome_Homo sapiens_hsa041420.73101425
88Autoimmune thyroid disease_Homo sapiens_hsa053200.73100316
89Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71111819
90ABC transporters_Homo sapiens_hsa020100.70925712
91Complement and coagulation cascades_Homo sapiens_hsa046100.70109451
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70104399
93Malaria_Homo sapiens_hsa051440.68248692
94Asthma_Homo sapiens_hsa053100.67188317
95Propanoate metabolism_Homo sapiens_hsa006400.67093380
96Type I diabetes mellitus_Homo sapiens_hsa049400.66656188
97Phagosome_Homo sapiens_hsa041450.66031995
98Carbon metabolism_Homo sapiens_hsa012000.62959276
99Fatty acid degradation_Homo sapiens_hsa000710.61807241
100Purine metabolism_Homo sapiens_hsa002300.56547823
101Biosynthesis of amino acids_Homo sapiens_hsa012300.56005557
102Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.55750764
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55492307
104N-Glycan biosynthesis_Homo sapiens_hsa005100.55426766
105Hematopoietic cell lineage_Homo sapiens_hsa046400.53684090
106Mineral absorption_Homo sapiens_hsa049780.52485475
107Pentose phosphate pathway_Homo sapiens_hsa000300.51647322
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.50988995
109Leukocyte transendothelial migration_Homo sapiens_hsa046700.50891120
110Fatty acid metabolism_Homo sapiens_hsa012120.50582274
111Starch and sucrose metabolism_Homo sapiens_hsa005000.47599228
112PPAR signaling pathway_Homo sapiens_hsa033200.46759528
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45193214
114Glycosaminoglycan degradation_Homo sapiens_hsa005310.44975412
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.43563642
116Antigen processing and presentation_Homo sapiens_hsa046120.42540253
117NF-kappa B signaling pathway_Homo sapiens_hsa040640.42105275
118Fat digestion and absorption_Homo sapiens_hsa049750.42059596
119Cyanoamino acid metabolism_Homo sapiens_hsa004600.41743357
120Caffeine metabolism_Homo sapiens_hsa002320.37901259
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33133043
122Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.32996946
123African trypanosomiasis_Homo sapiens_hsa051430.32897007

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