WNT8A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by RNA (GO:0060966)5.35894849
2regulation of posttranscriptional gene silencing (GO:0060147)5.35894849
3regulation of gene silencing by miRNA (GO:0060964)5.35894849
4establishment of integrated proviral latency (GO:0075713)5.23057759
5female gonad development (GO:0008585)4.91461631
6facial nerve structural organization (GO:0021612)4.79784286
7folic acid-containing compound biosynthetic process (GO:0009396)4.73117899
8histone arginine methylation (GO:0034969)4.67919115
9DNA double-strand break processing (GO:0000729)4.59505092
10DNA unwinding involved in DNA replication (GO:0006268)4.55171826
11peptidyl-arginine omega-N-methylation (GO:0035247)4.52329572
12cell migration involved in gastrulation (GO:0042074)4.40560865
13positive regulation of hair follicle development (GO:0051798)4.39645110
14positive regulation of hair cycle (GO:0042635)4.39645110
15ribosome assembly (GO:0042255)4.34576388
16pre-miRNA processing (GO:0031054)4.28606397
17mitotic metaphase plate congression (GO:0007080)4.26013047
18formation of translation preinitiation complex (GO:0001731)4.22400029
19DNA ligation (GO:0006266)4.20058784
20nodal signaling pathway (GO:0038092)4.19586893
21DNA replication initiation (GO:0006270)4.14638103
22DNA strand elongation involved in DNA replication (GO:0006271)4.13875450
23double-strand break repair via nonhomologous end joining (GO:0006303)4.12710604
24non-recombinational repair (GO:0000726)4.12710604
25peptidyl-arginine methylation (GO:0018216)4.09946103
26peptidyl-arginine N-methylation (GO:0035246)4.09946103
27ribosomal large subunit biogenesis (GO:0042273)4.07669392
28maturation of SSU-rRNA (GO:0030490)4.06756516
29regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901214.04552371
30nuclear pore organization (GO:0006999)4.04162667
31nucleobase biosynthetic process (GO:0046112)4.02907482
32IMP biosynthetic process (GO:0006188)4.01218518
33paraxial mesoderm development (GO:0048339)4.00158060
34DNA strand elongation (GO:0022616)3.99830238
35viral transcription (GO:0019083)3.95884044
36DNA replication checkpoint (GO:0000076)3.92979089
37translational termination (GO:0006415)3.92031262
38establishment of viral latency (GO:0019043)3.90879276
39ribosomal small subunit assembly (GO:0000028)3.88311820
40signal transduction involved in regulation of gene expression (GO:0023019)3.84377804
41DNA replication-dependent nucleosome assembly (GO:0006335)3.82428829
42DNA replication-dependent nucleosome organization (GO:0034723)3.82428829
43negative regulation of DNA recombination (GO:0045910)3.81307463
44anterior/posterior axis specification, embryo (GO:0008595)3.79781944
45regulation of centriole replication (GO:0046599)3.77301423
46protein localization to kinetochore (GO:0034501)3.76483883
47telomere maintenance via semi-conservative replication (GO:0032201)3.75643362
48cranial nerve structural organization (GO:0021604)3.72690086
49rRNA modification (GO:0000154)3.72655623
50purine nucleobase biosynthetic process (GO:0009113)3.68680743
51DNA catabolic process, exonucleolytic (GO:0000738)3.65007173
52blastocyst development (GO:0001824)3.64649454
53ribosomal small subunit biogenesis (GO:0042274)3.60298908
54metaphase plate congression (GO:0051310)3.58277944
55ribonucleoprotein complex biogenesis (GO:0022613)3.57204874
56regulation of double-strand break repair via homologous recombination (GO:0010569)3.56741435
57mitotic nuclear envelope disassembly (GO:0007077)3.55210126
58replication fork processing (GO:0031297)3.54763936
59nuclear pore complex assembly (GO:0051292)3.54476682
60translational elongation (GO:0006414)3.54456446
61chromatin remodeling at centromere (GO:0031055)3.53663365
62translational initiation (GO:0006413)3.48850685
63CENP-A containing nucleosome assembly (GO:0034080)3.47779808
64ribosome biogenesis (GO:0042254)3.46646261
65post-anal tail morphogenesis (GO:0036342)3.45189931
66IMP metabolic process (GO:0046040)3.42524880
67telomere maintenance via telomere lengthening (GO:0010833)3.40382185
68regulation of mesoderm development (GO:2000380)3.39478349
69ncRNA catabolic process (GO:0034661)3.39317416
70nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.39163182
71telomere maintenance via recombination (GO:0000722)3.37608065
72cullin deneddylation (GO:0010388)3.37320977
73regulation of hair follicle development (GO:0051797)3.35400552
74regulation of translational termination (GO:0006449)3.35340104
75primitive streak formation (GO:0090009)3.35008226
76cell fate commitment involved in formation of primary germ layer (GO:0060795)3.34712900
77positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.34167075
78RNA-dependent DNA replication (GO:0006278)3.33729353
79spliceosomal snRNP assembly (GO:0000387)3.33663261
80mitotic recombination (GO:0006312)3.33407511
81spliceosomal complex assembly (GO:0000245)3.32527649
82negative regulation of ligase activity (GO:0051352)3.31678541
83negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.31678541
84lung-associated mesenchyme development (GO:0060484)3.29721505
85rRNA processing (GO:0006364)3.29186475
86mitotic sister chromatid segregation (GO:0000070)3.28520436
87membrane disassembly (GO:0030397)3.28070962
88nuclear envelope disassembly (GO:0051081)3.28070962
89regulation of helicase activity (GO:0051095)3.26925817
90regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.24202606
91negative regulation of androgen receptor signaling pathway (GO:0060766)3.20685268
92DNA duplex unwinding (GO:0032508)3.20248222
93maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.19587942
94regulation of nuclear cell cycle DNA replication (GO:0033262)3.19551189
95DNA replication-independent nucleosome assembly (GO:0006336)3.18688751
96DNA replication-independent nucleosome organization (GO:0034724)3.18688751
97regulation of cellular amino acid metabolic process (GO:0006521)3.18678679
98rRNA metabolic process (GO:0016072)3.18078132
99DNA geometric change (GO:0032392)3.17903321
100cellular protein complex disassembly (GO:0043624)3.16495766
101somatic hypermutation of immunoglobulin genes (GO:0016446)3.13944698
102somatic diversification of immune receptors via somatic mutation (GO:0002566)3.13944698
103heterochromatin organization (GO:0070828)3.13630137
104regulation of centrosome cycle (GO:0046605)3.12031253
105protein deneddylation (GO:0000338)3.11557855
106histone exchange (GO:0043486)3.11283886
107kinetochore organization (GO:0051383)3.10919200
108ATP-dependent chromatin remodeling (GO:0043044)3.10076940
109DNA strand renaturation (GO:0000733)3.09867400
110viral life cycle (GO:0019058)3.09662517
111regulation of mitochondrial translation (GO:0070129)3.09502714
112establishment of chromosome localization (GO:0051303)3.07260874
113protein localization to chromosome, centromeric region (GO:0071459)3.07014745
114SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.06626738
115positive regulation of SMAD protein import into nucleus (GO:0060391)3.06353829
116regulation of telomere maintenance via telomerase (GO:0032210)3.06311930
117pteridine-containing compound biosynthetic process (GO:0042559)3.04373665
118negative regulation of chromosome segregation (GO:0051985)3.02431972
119protein complex localization (GO:0031503)3.02211633
120nucleotide-excision repair, DNA gap filling (GO:0006297)3.01199520
121cotranslational protein targeting to membrane (GO:0006613)3.01102925
122negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.00876474
123anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.00583590
124tetrahydrofolate metabolic process (GO:0046653)2.99789853
125protein prenylation (GO:0018342)2.98975157
126prenylation (GO:0097354)2.98975157
127protein targeting to ER (GO:0045047)2.98274076
128negative regulation of activin receptor signaling pathway (GO:0032926)2.97437397
129kinetochore assembly (GO:0051382)2.96687306
130regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.96168033
131regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.95516944
132RNA splicing, via transesterification reactions (GO:0000375)2.95163058
133negative regulation of mitotic sister chromatid separation (GO:2000816)2.94719703
134negative regulation of mitotic sister chromatid segregation (GO:0033048)2.94719703
135negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.94719703
136negative regulation of sister chromatid segregation (GO:0033046)2.94719703
137protein complex disassembly (GO:0043241)2.94326602
138regulation of cell fate specification (GO:0042659)2.93898249
139regulation of mitotic spindle checkpoint (GO:1903504)2.93634953
140regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.93634953
141negative regulation of gene silencing (GO:0060969)2.92460884
142regulation of development, heterochronic (GO:0040034)2.91559387
143positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.89672194
144anatomical structure arrangement (GO:0048532)2.89111416
145negative regulation of DNA-dependent DNA replication (GO:2000104)2.87452821
146proteasome assembly (GO:0043248)2.87091261
147outer ear morphogenesis (GO:0042473)2.82801829
148positive regulation of ligase activity (GO:0051351)2.81178635
149establishment of protein localization to mitochondrial membrane (GO:0090151)2.80400150
150chromatin assembly or disassembly (GO:0006333)2.80224296
151signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.76360190
152signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.76360190
153signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.76360190
154positive regulation of catenin import into nucleus (GO:0035413)2.74705962
155negative regulation of cell fate specification (GO:0009996)2.73460655
156signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.72503429
157intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.72503429
158regulation of ubiquitin-protein transferase activity (GO:0051438)2.70770093
159cell cycle G1/S phase transition (GO:0044843)2.70313614
160G1/S transition of mitotic cell cycle (GO:0000082)2.70313614

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.37892323
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.87430058
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.72673396
4MYC_19079543_ChIP-ChIP_MESCs_Mouse3.63639689
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.55889710
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54307207
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.21408008
8MYC_19030024_ChIP-ChIP_MESCs_Mouse3.17283783
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.13520340
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.95654801
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.85287275
12POU5F1_16153702_ChIP-ChIP_HESCs_Human2.67088018
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.63614326
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.62763628
15XRN2_22483619_ChIP-Seq_HELA_Human2.62590878
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.61013624
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.60451811
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.60177843
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.58666052
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.52642423
21MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.26236327
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.24365222
23KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.16219056
24KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.16219056
25KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.16219056
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.14350704
27NANOG_18555785_ChIP-Seq_MESCs_Mouse2.09774142
28AR_21909140_ChIP-Seq_LNCAP_Human2.02190475
29TTF2_22483619_ChIP-Seq_HELA_Human2.01188607
30VDR_22108803_ChIP-Seq_LS180_Human2.01127482
31* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.98375287
32KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.98243834
33POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.97904098
34ELF1_17652178_ChIP-ChIP_JURKAT_Human1.96408590
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94668223
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.94030468
37SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.93018835
38VDR_23849224_ChIP-Seq_CD4+_Human1.91325540
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89272479
40* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.87726547
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.87119441
42IRF1_19129219_ChIP-ChIP_H3396_Human1.84345682
43NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83122981
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.80821215
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.79878862
46ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.78461323
47DCP1A_22483619_ChIP-Seq_HELA_Human1.78042115
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.77906126
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.73672097
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.73565823
51ELK1_19687146_ChIP-ChIP_HELA_Human1.73094616
52EWS_26573619_Chip-Seq_HEK293_Human1.70714996
53ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.64647403
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62796255
55KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.61620961
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.61339970
57GABP_19822575_ChIP-Seq_HepG2_Human1.59894795
58FOXP3_21729870_ChIP-Seq_TREG_Human1.59872748
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58845642
60EGR1_19374776_ChIP-ChIP_THP-1_Human1.57078821
61PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52923666
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.49101913
63* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.47983964
64ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47870513
65FUS_26573619_Chip-Seq_HEK293_Human1.46189692
66NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.45501947
67YY1_21170310_ChIP-Seq_MESCs_Mouse1.45484625
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.43682860
69ZNF274_21170338_ChIP-Seq_K562_Hela1.42790893
70ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39906329
71MYC_18940864_ChIP-ChIP_HL60_Human1.39019304
72NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.37974265
73CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.36165522
74SALL1_21062744_ChIP-ChIP_HESCs_Human1.35139459
75HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.34198356
76KDM5A_27292631_Chip-Seq_BREAST_Human1.26396845
77SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.22544535
78CIITA_25753668_ChIP-Seq_RAJI_Human1.22495280
79* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.21348895
80* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.19624357
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.19361994
82NANOG_16153702_ChIP-ChIP_HESCs_Human1.19329386
83* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.17987662
84SOX2_18692474_ChIP-Seq_MEFs_Mouse1.17771505
85FLI1_27457419_Chip-Seq_LIVER_Mouse1.17731111
86SRF_21415370_ChIP-Seq_HL-1_Mouse1.17201272
87PADI4_21655091_ChIP-ChIP_MCF-7_Human1.16316405
88CTBP2_25329375_ChIP-Seq_LNCAP_Human1.15093806
89* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.13870317
90STAT3_1855785_ChIP-Seq_MESCs_Mouse1.13618765
91P300_19829295_ChIP-Seq_ESCs_Human1.13479273
92FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.13349898
93TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.13270482
94* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10943189
95TFEB_21752829_ChIP-Seq_HELA_Human1.10794817
96* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.09324128
97POU5F1_16518401_ChIP-PET_MESCs_Mouse1.09207779
98PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08577027
99CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.08529764
100ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05251095
101NANOG_21062744_ChIP-ChIP_HESCs_Human1.04418500
102HOXB4_20404135_ChIP-ChIP_EML_Mouse1.04106223
103TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01610567
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00357129
105TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00357129
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99593262
107CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99558926
108GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.99293267
109MYC_22102868_ChIP-Seq_BL_Human0.98132363
110SOX2_18692474_ChIP-Seq_MESCs_Mouse0.96536031
111CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95741922
112SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95084943
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94272821
114* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.94261546
115SOX2_16153702_ChIP-ChIP_HESCs_Human0.94139609
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93649147
117* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.93518921
118RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93406491
119SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.92010052
120* NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.91525250
121* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91338112
122PCGF2_27294783_Chip-Seq_ESCs_Mouse0.89976109
123POU3F2_20337985_ChIP-ChIP_501MEL_Human0.88854310
124TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.88768800
125TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.88684778
126DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.88555925
127SMAD3_21741376_ChIP-Seq_EPCs_Human0.87067349
128BMI1_23680149_ChIP-Seq_NPCS_Mouse0.86727866

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004957_abnormal_blastocyst_morpholog4.36616393
2MP0003693_abnormal_embryo_hatching4.24246586
3MP0004133_heterotaxia4.23434085
4MP0010094_abnormal_chromosome_stability4.00212498
5MP0003077_abnormal_cell_cycle3.75931609
6MP0003111_abnormal_nucleus_morphology3.50231103
7MP0003890_abnormal_embryonic-extraembry3.34608067
8MP0008057_abnormal_DNA_replication3.26947124
9MP0008058_abnormal_DNA_repair3.08347210
10MP0008932_abnormal_embryonic_tissue2.81945777
11MP0001730_embryonic_growth_arrest2.79039906
12MP0003806_abnormal_nucleotide_metabolis2.73551660
13MP0008007_abnormal_cellular_replicative2.68306908
14MP0008877_abnormal_DNA_methylation2.66248161
15MP0010030_abnormal_orbit_morphology2.66179621
16MP0002102_abnormal_ear_morphology2.66030674
17MP0003123_paternal_imprinting2.44840065
18MP0003880_abnormal_central_pattern2.18367554
19MP0000350_abnormal_cell_proliferation2.17428212
20MP0003119_abnormal_digestive_system2.15282886
21MP0006292_abnormal_olfactory_placode2.15084103
22MP0002084_abnormal_developmental_patter2.08668078
23MP0001672_abnormal_embryogenesis/_devel2.05405119
24MP0005380_embryogenesis_phenotype2.05405119
25MP0003941_abnormal_skin_development2.02945429
26MP0001293_anophthalmia1.99640077
27MP0001697_abnormal_embryo_size1.99050547
28MP0003283_abnormal_digestive_organ1.97537655
29MP0002085_abnormal_embryonic_tissue1.94514109
30MP0002653_abnormal_ependyma_morphology1.91088820
31MP0003136_yellow_coat_color1.89664212
32MP0010352_gastrointestinal_tract_polyps1.85961493
33MP0002111_abnormal_tail_morphology1.85569620
34MP0002254_reproductive_system_inflammat1.82211347
35MP0000678_abnormal_parathyroid_gland1.78028758
36MP0003984_embryonic_growth_retardation1.73984204
37MP0004197_abnormal_fetal_growth/weight/1.73628252
38MP0003937_abnormal_limbs/digits/tail_de1.71315485
39MP0002088_abnormal_embryonic_growth/wei1.68597591
40MP0002080_prenatal_lethality1.61816314
41MP0003121_genomic_imprinting1.58635869
42MP0002086_abnormal_extraembryonic_tissu1.55930776
43MP0000537_abnormal_urethra_morphology1.54865614
44MP0001485_abnormal_pinna_reflex1.52701855
45MP0006054_spinal_hemorrhage1.50728067
46MP0002160_abnormal_reproductive_system1.45755609
47MP0001486_abnormal_startle_reflex1.40575245
48MP0001727_abnormal_embryo_implantation1.39673762
49MP0003315_abnormal_perineum_morphology1.38627289
50MP0003567_abnormal_fetal_cardiomyocyte1.31605305
51MP0008789_abnormal_olfactory_epithelium1.31514001
52MP0006072_abnormal_retinal_apoptosis1.31065120
53MP0003195_calcinosis1.30774686
54MP0003786_premature_aging1.30749361
55MP0005253_abnormal_eye_physiology1.28046643
56MP0003718_maternal_effect1.27946581
57MP0003938_abnormal_ear_development1.26074606
58MP0002938_white_spotting1.22293479
59MP0003755_abnormal_palate_morphology1.21753182
60MP0000313_abnormal_cell_death1.21481995
61MP0000462_abnormal_digestive_system1.21050329
62MP0005499_abnormal_olfactory_system1.19287153
63MP0005394_taste/olfaction_phenotype1.19287153
64MP0010307_abnormal_tumor_latency1.18456751
65MP0001286_abnormal_eye_development1.17258738
66MP0004885_abnormal_endolymph1.14570408
67MP0000049_abnormal_middle_ear1.13131051
68MP0000428_abnormal_craniofacial_morphol1.12444793
69MP0000432_abnormal_head_morphology1.10103466
70MP0009046_muscle_twitch1.05207171
71MP0002127_abnormal_cardiovascular_syste1.05177602
72MP0010368_abnormal_lymphatic_system1.04674496
73MP0003861_abnormal_nervous_system1.03139750
74MP0006035_abnormal_mitochondrial_morpho1.01979854
75MP0009053_abnormal_anal_canal1.00935802
76MP0009672_abnormal_birth_weight1.00595107
77MP0001299_abnormal_eye_distance/1.00375167
78MP0001529_abnormal_vocalization0.99229822
79MP0000778_abnormal_nervous_system0.96256336
80MP0004264_abnormal_extraembryonic_tissu0.92652819
81MP0004215_abnormal_myocardial_fiber0.91946619
82MP0002734_abnormal_mechanical_nocicepti0.91173841
83MP0003385_abnormal_body_wall0.88904002
84MP0002932_abnormal_joint_morphology0.88737601
85MP0001915_intracranial_hemorrhage0.88253724
86MP0002234_abnormal_pharynx_morphology0.86687992
87MP0002163_abnormal_gland_morphology0.85433283
88MP0005389_reproductive_system_phenotype0.84497823
89MP0003942_abnormal_urinary_system0.83978202
90MP0000566_synostosis0.83498162
91MP0000579_abnormal_nail_morphology0.83421208
92MP0003935_abnormal_craniofacial_develop0.82528748
93MP0002752_abnormal_somatic_nervous0.82343855
94MP0009697_abnormal_copulation0.82010825
95MP0000631_abnormal_neuroendocrine_gland0.81685931
96MP0002638_abnormal_pupillary_reflex0.81654461
97MP0005076_abnormal_cell_differentiation0.81445373
98MP0002092_abnormal_eye_morphology0.80899621
99MP0002733_abnormal_thermal_nociception0.80835399
100MP0005391_vision/eye_phenotype0.80647370
101MP0001177_atelectasis0.80452787
102MP0002396_abnormal_hematopoietic_system0.80071321
103MP0002925_abnormal_cardiovascular_devel0.79666767
104MP0001348_abnormal_lacrimal_gland0.77832506
105MP0002736_abnormal_nociception_after0.77728992
106MP0002114_abnormal_axial_skeleton0.77426863
107MP0005367_renal/urinary_system_phenotyp0.76926358
108MP0000516_abnormal_urinary_system0.76926358
109MP0005266_abnormal_metabolism0.76384104
110MP0009379_abnormal_foot_pigmentation0.76367153
111MP0002019_abnormal_tumor_incidence0.76340730
112MP0002210_abnormal_sex_determination0.75854765
113MP0003186_abnormal_redox_activity0.75370271
114MP0002184_abnormal_innervation0.75337949
115MP0001929_abnormal_gametogenesis0.75011373
116MP0000750_abnormal_muscle_regeneration0.74847243
117MP0005551_abnormal_eye_electrophysiolog0.74433840
118MP0005248_abnormal_Harderian_gland0.74355331
119MP0003137_abnormal_impulse_conducting0.74028159
120MP0009703_decreased_birth_body0.73115755
121MP0002272_abnormal_nervous_system0.72870673
122MP0000490_abnormal_crypts_of0.72803512
123MP0001145_abnormal_male_reproductive0.72723913
124MP0000762_abnormal_tongue_morphology0.72543170
125MP0002233_abnormal_nose_morphology0.71701408
126MP0002697_abnormal_eye_size0.69394115
127MP0002332_abnormal_exercise_endurance0.68799511
128MP0003566_abnormal_cell_adhesion0.68109205
129MP0002249_abnormal_larynx_morphology0.65773588
130MP0000733_abnormal_muscle_development0.64627276
131MP0002751_abnormal_autonomic_nervous0.61278234
132MP0000653_abnormal_sex_gland0.59801087
133MP0003936_abnormal_reproductive_system0.57953354
134MP0002116_abnormal_craniofacial_bone0.57616470
135MP0001853_heart_inflammation0.57609791
136MP0001849_ear_inflammation0.57438787
137MP0002098_abnormal_vibrissa_morphology0.56658366
138MP0005377_hearing/vestibular/ear_phenot0.56437240
139MP0003878_abnormal_ear_physiology0.56437240
140MP0000470_abnormal_stomach_morphology0.55553627

Predicted human phenotypes

RankGene SetZ-score
1Abdominal situs inversus (HP:0003363)4.53280007
2Abnormality of abdominal situs (HP:0011620)4.53280007
3Birth length less than 3rd percentile (HP:0003561)4.25282871
4Supernumerary spleens (HP:0009799)4.17869551
5Colon cancer (HP:0003003)3.76256213
6Reticulocytopenia (HP:0001896)3.70113275
7Selective tooth agenesis (HP:0001592)3.57876173
8Asplenia (HP:0001746)3.50172114
9Aplasia/Hypoplasia of the spleen (HP:0010451)3.49982579
10Septo-optic dysplasia (HP:0100842)3.48980845
11Ependymoma (HP:0002888)3.48296340
12Rib fusion (HP:0000902)3.38660461
13Abnormality of the labia minora (HP:0012880)3.32632726
14Absent radius (HP:0003974)3.32413862
15Abnormality of cochlea (HP:0000375)3.31567275
16Oral leukoplakia (HP:0002745)3.31422828
17Medulloblastoma (HP:0002885)3.26812957
18Chromsome breakage (HP:0040012)3.26074357
19Abnormal number of incisors (HP:0011064)3.18100862
20Rough bone trabeculation (HP:0100670)3.15768134
21Abnormal lung lobation (HP:0002101)3.11968126
22Aplasia involving forearm bones (HP:0009822)3.11008162
23Absent forearm bone (HP:0003953)3.11008162
24Short middle phalanx of the 5th finger (HP:0004220)3.10169169
25Aplasia/hypoplasia of the humerus (HP:0006507)3.00680711
26Breast aplasia (HP:0100783)3.00292122
27Chromosomal breakage induced by crosslinking agents (HP:0003221)2.94239136
28Morphological abnormality of the inner ear (HP:0011390)2.90975645
29Carpal bone hypoplasia (HP:0001498)2.89637432
30Cleft eyelid (HP:0000625)2.87999683
31Agnosia (HP:0010524)2.86286045
32Patellar aplasia (HP:0006443)2.83843550
33Chin dimple (HP:0010751)2.81056664
34Meckel diverticulum (HP:0002245)2.79484043
35Breast hypoplasia (HP:0003187)2.79474572
36Preaxial foot polydactyly (HP:0001841)2.79407348
37Trismus (HP:0000211)2.78723830
38Aplasia/Hypoplasia of the breasts (HP:0010311)2.66906341
39Aplasia/Hypoplasia of the tibia (HP:0005772)2.65159866
40Abnormality of the ileum (HP:0001549)2.64215952
41Degeneration of anterior horn cells (HP:0002398)2.63648287
42Abnormality of the anterior horn cell (HP:0006802)2.63648287
43Short tibia (HP:0005736)2.59632921
44Bifid tongue (HP:0010297)2.56805893
45Split foot (HP:0001839)2.55707345
46Cellular immunodeficiency (HP:0005374)2.55197306
47Aplasia/Hypoplasia of the patella (HP:0006498)2.54561418
48Abnormal trabecular bone morphology (HP:0100671)2.53376475
49Cortical dysplasia (HP:0002539)2.51759257
50Absent thumb (HP:0009777)2.49847277
51Tracheoesophageal fistula (HP:0002575)2.49539286
52Aplastic anemia (HP:0001915)2.48461501
53Cerebral hypomyelination (HP:0006808)2.46403659
54Aplasia/Hypoplasia of the sternum (HP:0006714)2.45189579
55Hyperglycinemia (HP:0002154)2.44813127
56Hepatoblastoma (HP:0002884)2.43695253
57Rectovaginal fistula (HP:0000143)2.42554776
58Rectal fistula (HP:0100590)2.42554776
59Short humerus (HP:0005792)2.41491797
60Macrocytic anemia (HP:0001972)2.41282578
61Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.40553046
62Facial cleft (HP:0002006)2.40365252
63Bilateral microphthalmos (HP:0007633)2.40026889
64Horseshoe kidney (HP:0000085)2.39326190
65Spinal muscular atrophy (HP:0007269)2.39020604
66Microretrognathia (HP:0000308)2.37789577
67Stenosis of the external auditory canal (HP:0000402)2.36848542
68Abnormality of chromosome stability (HP:0003220)2.36592154
69Neoplasm of the pancreas (HP:0002894)2.36377065
70Cutaneous syndactyly (HP:0012725)2.35263139
71Glossoptosis (HP:0000162)2.33977481
72Impaired vibration sensation in the lower limbs (HP:0002166)2.31932308
73Aplasia/Hypoplasia of the uvula (HP:0010293)2.30393391
74Abnormality of cells of the erythroid lineage (HP:0012130)2.30376520
75Short 5th finger (HP:0009237)2.29042030
76Progressive external ophthalmoplegia (HP:0000590)2.28747682
77Premature graying of hair (HP:0002216)2.27850485
78Atresia of the external auditory canal (HP:0000413)2.25402725
79Abnormality of the preputium (HP:0100587)2.23182938
80Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.22860679
81Coronal craniosynostosis (HP:0004440)2.22747195
82Multiple enchondromatosis (HP:0005701)2.21935225
83Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.21642168
84Fused cervical vertebrae (HP:0002949)2.21487803
85Impulsivity (HP:0100710)2.21261419
86Hypoplastic female external genitalia (HP:0012815)2.19543783
87Nonprogressive disorder (HP:0003680)2.19387633
88Hemivertebrae (HP:0002937)2.18133410
89Preaxial hand polydactyly (HP:0001177)2.17985821
90Oligodactyly (hands) (HP:0001180)2.17271991
91Abnormality of the astrocytes (HP:0100707)2.16635679
92Astrocytoma (HP:0009592)2.16635679
93Esophageal atresia (HP:0002032)2.15260853
94Abnormality of pyrimidine metabolism (HP:0004353)2.14001325
95Deviation of the thumb (HP:0009603)2.13804544
96Abnormality of the septum pellucidum (HP:0007375)2.13576852
97Hypoplastic pelvis (HP:0008839)2.13554904
98Microvesicular hepatic steatosis (HP:0001414)2.12521648
99Proximal placement of thumb (HP:0009623)2.12373506
100Abnormality of glycolysis (HP:0004366)2.12051570
101Increased serum pyruvate (HP:0003542)2.12051570
102Embryonal renal neoplasm (HP:0011794)2.11698082
103Rhabdomyosarcoma (HP:0002859)2.10665243
104Cutaneous finger syndactyly (HP:0010554)2.10537515
105Anophthalmia (HP:0000528)2.09750150
106Labial hypoplasia (HP:0000066)2.08587172
107Omphalocele (HP:0001539)2.06876408
108Hyperglycinuria (HP:0003108)2.04813535
109Nephroblastoma (Wilms tumor) (HP:0002667)2.04413386
110Preauricular skin tag (HP:0000384)2.04118459
111Intestinal atresia (HP:0011100)2.02639018
112Pallor (HP:0000980)2.02355842
113Biliary tract neoplasm (HP:0100574)2.01232713
114Myelomeningocele (HP:0002475)1.99312920
115Missing ribs (HP:0000921)1.98187761
116Duodenal stenosis (HP:0100867)1.97839799
117Small intestinal stenosis (HP:0012848)1.97839799
118Absent septum pellucidum (HP:0001331)1.97731015
119Anal stenosis (HP:0002025)1.96127948
120Intestinal fistula (HP:0100819)1.95460722
121Abnormal auditory evoked potentials (HP:0006958)1.95329260
122Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.95260213
123Ectopic kidney (HP:0000086)1.94650930
124Vertebral fusion (HP:0002948)1.94089099
125Abnormality of the duodenum (HP:0002246)1.93710644
126Absent eyebrow (HP:0002223)1.93348490
127Mixed hearing impairment (HP:0000410)1.92522515
128Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90044066
129Ankyloglossia (HP:0010296)1.89578156
130Broad thumb (HP:0011304)1.89382016
131Long eyelashes (HP:0000527)1.88192075
132Methylmalonic aciduria (HP:0012120)1.86716850
133Vaginal fistula (HP:0004320)1.86283897
134Median cleft lip (HP:0000161)1.85332238
135Triphalangeal thumb (HP:0001199)1.85317268
136Abnormality of the phalanges of the 5th finger (HP:0004213)1.84614796
137Short hallux (HP:0010109)1.84025935
138High anterior hairline (HP:0009890)1.83187545
139Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.82797584
140Amyotrophic lateral sclerosis (HP:0007354)1.82087094
141Transposition of the great arteries (HP:0001669)1.81712342
142Abnormal connection of the cardiac segments (HP:0011545)1.81712342
143Abnormal ventriculo-arterial connection (HP:0011563)1.81712342
144Decreased lacrimation (HP:0000633)1.80908008
145Supernumerary bones of the axial skeleton (HP:0009144)1.80667929
146Skin tags (HP:0010609)1.79208217
147Abnormality of the fetal cardiovascular system (HP:0010948)1.78960054
148Single umbilical artery (HP:0001195)1.78960054
149Aplasia/Hypoplasia of the hallux (HP:0008362)1.77823085
150Abnormality of the clitoris (HP:0000056)1.77730202
151Cupped ear (HP:0000378)1.76801079
152Renal hypoplasia (HP:0000089)1.76001395
153Gonadotropin excess (HP:0000837)1.74210649
154Duplication of thumb phalanx (HP:0009942)1.72172473
155Abnormality of the parathyroid morphology (HP:0011766)1.70205101
156Aplasia involving bones of the extremities (HP:0009825)1.69918162
157Aplasia involving bones of the upper limbs (HP:0009823)1.69918162
158Aplasia of the phalanges of the hand (HP:0009802)1.69918162
159Abnormality of serine family amino acid metabolism (HP:0010894)1.69888897
160Abnormality of glycine metabolism (HP:0010895)1.69888897

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.30296633
2CDC74.34721566
3MAP4K23.97045447
4EPHA43.72025721
5TSSK63.57159815
6MAP3K43.47656387
7MAP2K73.18781337
8SRPK13.06705294
9TLK12.92016172
10WEE12.88467242
11WNK32.63867325
12PLK42.54805960
13EPHA22.53505862
14NEK12.42128232
15TTK2.38520820
16PASK2.30054935
17VRK12.24071473
18EIF2AK12.20785453
19NEK22.16418054
20CDK122.16384708
21PLK32.14027134
22PLK12.06991091
23LATS22.04677466
24MKNK11.93454645
25STK38L1.89078731
26TESK21.88596703
27CDK71.85914823
28ALK1.79345437
29ATR1.66273927
30AURKB1.64253996
31RPS6KB21.58557359
32EIF2AK31.53044449
33CSNK1G21.51422358
34TIE11.46951793
35CHEK11.38988458
36MAP2K41.37366646
37MKNK21.32516852
38AURKA1.26986783
39PAK41.25567366
40TGFBR11.21079338
41MAP3K81.19781197
42TESK11.18327507
43FRK1.18276420
44STK101.18095868
45CSNK1G31.18015147
46TYRO31.15171800
47PBK1.12091053
48CSNK1G11.11974616
49CASK1.09663239
50CSNK1A1L1.08723083
51CDK61.08313797
52BMPR1B1.00707642
53PNCK0.97959325
54ATM0.97510368
55BCKDK0.95833137
56CHEK20.95406404
57AKT30.95187999
58CDK40.94809375
59CDK20.90482447
60CSNK2A20.86625375
61BRD40.84296210
62STK40.82240671
63BMX0.81275118
64BCR0.79897841
65DYRK30.79498099
66DYRK20.78204136
67RPS6KA40.77136028
68ADRBK20.75489549
69TRIM280.75445008
70CSNK1E0.73368662
71CDK10.72778906
72TAF10.72729868
73FGFR10.71872893
74NTRK20.71489328
75KDR0.70609660
76CSNK2A10.70538062
77ACVR1B0.69883723
78FGFR20.68643811
79LIMK10.68295823
80MST40.68174930
81DAPK10.65982933
82MET0.64195663
83AKT20.61393452
84EIF2AK20.61160136
85YES10.61029941
86LATS10.60698918
87BRSK20.59259858
88PDK20.57942292
89ICK0.57924935
90PAK10.57905963
91PIM10.57355151
92NME10.57013363
93STK160.56548268
94PRKCI0.56526344
95MAP3K100.55369244
96STK30.54005148
97MINK10.53575162
98NME20.52381581
99PRKDC0.49510427
100CDK80.47210988
101CAMK1G0.47041736
102PKN20.46276063
103MAP3K110.46063734
104DYRK1A0.44494320
105CDK190.44033846
106MAP3K50.43446505
107ZAK0.42773934
108PRKCG0.42423986
109CLK10.41664249
110FLT30.39935035
111CDK180.39763897
112CDK150.38105310
113MTOR0.37528961
114STK240.37268549
115CDK140.37096876
116BRSK10.37021498
117BRAF0.36650822
118MAPK90.36398497
119PLK20.36071080
120RPS6KA50.34915641
121ERBB30.34758491
122CAMK1D0.34682276
123FGR0.34610529
124NUAK10.33176382
125DAPK30.32059748
126CSNK1D0.31754967
127LRRK20.31524681
128ABL20.31373784
129SCYL20.29168634
130OXSR10.29141227
131UHMK10.28437209
132MELK0.28392505
133MAP3K30.25727165
134GSK3B0.25526353
135MAPK140.24591364
136GRK60.24127645
137EEF2K0.22387011
138MAP2K20.22164994
139AKT10.21500445
140TEC0.21450216
141CDK11A0.21169698
142MAPK10.21157514

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.61227893
2Mismatch repair_Homo sapiens_hsa034304.47734631
3Ribosome_Homo sapiens_hsa030104.05509143
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.91324955
5Proteasome_Homo sapiens_hsa030503.74837232
6Spliceosome_Homo sapiens_hsa030403.73506009
7One carbon pool by folate_Homo sapiens_hsa006703.61495283
8RNA polymerase_Homo sapiens_hsa030203.59311938
9RNA transport_Homo sapiens_hsa030133.16071418
10Homologous recombination_Homo sapiens_hsa034402.86551169
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.69302383
12Nucleotide excision repair_Homo sapiens_hsa034202.64808670
13Cell cycle_Homo sapiens_hsa041102.48304662
14Pyrimidine metabolism_Homo sapiens_hsa002402.43149576
15Base excision repair_Homo sapiens_hsa034102.41278371
16Non-homologous end-joining_Homo sapiens_hsa034502.34628402
17RNA degradation_Homo sapiens_hsa030182.16128566
18Fanconi anemia pathway_Homo sapiens_hsa034602.11597657
19mRNA surveillance pathway_Homo sapiens_hsa030151.85714541
20Basal transcription factors_Homo sapiens_hsa030221.83644916
21beta-Alanine metabolism_Homo sapiens_hsa004101.51485507
22Propanoate metabolism_Homo sapiens_hsa006401.51085450
23p53 signaling pathway_Homo sapiens_hsa041151.46992099
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.37599307
25Purine metabolism_Homo sapiens_hsa002301.35396378
26Histidine metabolism_Homo sapiens_hsa003401.35303199
27Biosynthesis of amino acids_Homo sapiens_hsa012301.31500286
28Nicotine addiction_Homo sapiens_hsa050331.27693782
29* Basal cell carcinoma_Homo sapiens_hsa052171.19226611
30Phototransduction_Homo sapiens_hsa047441.13912769
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12916809
32Oocyte meiosis_Homo sapiens_hsa041141.07930095
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.06851429
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.06503187
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06298794
36Epstein-Barr virus infection_Homo sapiens_hsa051691.03367758
37Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02090516
38Thyroid cancer_Homo sapiens_hsa052160.99811704
39* Hippo signaling pathway_Homo sapiens_hsa043900.99055202
40Systemic lupus erythematosus_Homo sapiens_hsa053220.96149456
41Ether lipid metabolism_Homo sapiens_hsa005650.95232779
42Huntingtons disease_Homo sapiens_hsa050160.91547771
43TGF-beta signaling pathway_Homo sapiens_hsa043500.91247066
44Cyanoamino acid metabolism_Homo sapiens_hsa004600.90806942
45Tryptophan metabolism_Homo sapiens_hsa003800.86467233
46Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.84497216
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81875675
48* Hedgehog signaling pathway_Homo sapiens_hsa043400.81314296
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78655791
50Linoleic acid metabolism_Homo sapiens_hsa005910.77993083
51* Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77766374
52Fatty acid metabolism_Homo sapiens_hsa012120.76677796
53Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73511481
54Viral carcinogenesis_Homo sapiens_hsa052030.72161631
55Parkinsons disease_Homo sapiens_hsa050120.71261814
56Fatty acid elongation_Homo sapiens_hsa000620.71039645
57MicroRNAs in cancer_Homo sapiens_hsa052060.68655878
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67157631
59Vitamin B6 metabolism_Homo sapiens_hsa007500.65856852
60Carbon metabolism_Homo sapiens_hsa012000.65831516
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64013012
62Oxidative phosphorylation_Homo sapiens_hsa001900.62873889
63Folate biosynthesis_Homo sapiens_hsa007900.62780695
64N-Glycan biosynthesis_Homo sapiens_hsa005100.60241387
65Olfactory transduction_Homo sapiens_hsa047400.57911944
66* HTLV-I infection_Homo sapiens_hsa051660.55791251
67Bladder cancer_Homo sapiens_hsa052190.55536813
68Adherens junction_Homo sapiens_hsa045200.55470569
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55227938
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.53228116
71Serotonergic synapse_Homo sapiens_hsa047260.52613060
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52590850
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51688860
74Fatty acid degradation_Homo sapiens_hsa000710.51224341
75Herpes simplex infection_Homo sapiens_hsa051680.50808339
76Melanoma_Homo sapiens_hsa052180.49750916
77Selenocompound metabolism_Homo sapiens_hsa004500.49209251
78Taste transduction_Homo sapiens_hsa047420.47677131
79Notch signaling pathway_Homo sapiens_hsa043300.47182928
80Fructose and mannose metabolism_Homo sapiens_hsa000510.45706565
81Tight junction_Homo sapiens_hsa045300.45690794
82Phenylalanine metabolism_Homo sapiens_hsa003600.43071671
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43015298
84Legionellosis_Homo sapiens_hsa051340.42185471
85Antigen processing and presentation_Homo sapiens_hsa046120.41039491
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.40987952
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40725485
88GABAergic synapse_Homo sapiens_hsa047270.39214655
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38713415
90* Wnt signaling pathway_Homo sapiens_hsa043100.38506781
91Long-term depression_Homo sapiens_hsa047300.38392574
92Glutathione metabolism_Homo sapiens_hsa004800.38350825
93HIF-1 signaling pathway_Homo sapiens_hsa040660.38158862
94* Pathways in cancer_Homo sapiens_hsa052000.37678427
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36672399
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36278803
97Alcoholism_Homo sapiens_hsa050340.35984384
98Arginine and proline metabolism_Homo sapiens_hsa003300.35186258
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33764695
100Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32736608
101Vitamin digestion and absorption_Homo sapiens_hsa049770.31829883
102Arginine biosynthesis_Homo sapiens_hsa002200.31218760
103Protein export_Homo sapiens_hsa030600.31005497
104Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.28685697
105Pyruvate metabolism_Homo sapiens_hsa006200.28371065
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.26288294
1072-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.26175271
108Peroxisome_Homo sapiens_hsa041460.25743691
109Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.25418540
110Nitrogen metabolism_Homo sapiens_hsa009100.25341118
111Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.22769194
112Tyrosine metabolism_Homo sapiens_hsa003500.22731206
113Metabolic pathways_Homo sapiens_hsa011000.22666826
114Morphine addiction_Homo sapiens_hsa050320.21798616
115Glutamatergic synapse_Homo sapiens_hsa047240.21669342
116Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21148161
117Small cell lung cancer_Homo sapiens_hsa052220.19398481
118Axon guidance_Homo sapiens_hsa043600.19391920
119Glycerolipid metabolism_Homo sapiens_hsa005610.18116389
120Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.18064208
121Pentose phosphate pathway_Homo sapiens_hsa000300.17439494
122* Melanogenesis_Homo sapiens_hsa049160.16510563
123Steroid biosynthesis_Homo sapiens_hsa001000.16478252
124Alzheimers disease_Homo sapiens_hsa050100.15848986
125Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.15786149
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.14266634
127Colorectal cancer_Homo sapiens_hsa052100.13858881
128Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.10007362
129Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09501762
130Lysine degradation_Homo sapiens_hsa003100.08544333
131Apoptosis_Homo sapiens_hsa042100.06992707
132Rap1 signaling pathway_Homo sapiens_hsa040150.04368975
133Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.04123306
134Cardiac muscle contraction_Homo sapiens_hsa042600.03594741
135Prostate cancer_Homo sapiens_hsa05215-0.0455079
136Sulfur relay system_Homo sapiens_hsa04122-0.0373418
137* Proteoglycans in cancer_Homo sapiens_hsa05205-0.0338076
138Glucagon signaling pathway_Homo sapiens_hsa04922-0.0306480
139Type I diabetes mellitus_Homo sapiens_hsa04940-0.0242492

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »