WDR83OS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.22065887
2ATP synthesis coupled proton transport (GO:0015986)7.37581196
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.37581196
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.28571481
5ribosomal small subunit assembly (GO:0000028)6.25295317
6respiratory electron transport chain (GO:0022904)6.10152426
7electron transport chain (GO:0022900)6.00341193
8DNA deamination (GO:0045006)5.74400727
9establishment of protein localization to mitochondrial membrane (GO:0090151)5.58770493
10proteasome assembly (GO:0043248)4.63254494
11protein neddylation (GO:0045116)4.42841849
12deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.22722861
13hydrogen ion transmembrane transport (GO:1902600)4.20665158
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.20206808
15viral transcription (GO:0019083)4.18216825
16ATP biosynthetic process (GO:0006754)4.16905461
17translational termination (GO:0006415)4.07821591
18cotranslational protein targeting to membrane (GO:0006613)4.07304046
19protein targeting to ER (GO:0045047)4.04309183
20purine nucleoside triphosphate biosynthetic process (GO:0009145)3.99987245
21purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.98544975
22protein localization to endoplasmic reticulum (GO:0070972)3.92082388
23signal peptide processing (GO:0006465)3.88114592
24response to interferon-beta (GO:0035456)3.84851340
25proton transport (GO:0015992)3.81523082
26translational elongation (GO:0006414)3.79609960
27establishment of protein localization to endoplasmic reticulum (GO:0072599)3.78648979
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.78575794
29negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.78475277
30hydrogen transport (GO:0006818)3.74172954
31protein targeting to mitochondrion (GO:0006626)3.72708460
32antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.69449176
33RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.67420782
34tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.67420782
35establishment of protein localization to mitochondrion (GO:0072655)3.60660732
36formation of translation preinitiation complex (GO:0001731)3.57288763
37ribosomal small subunit biogenesis (GO:0042274)3.55875746
38maturation of SSU-rRNA (GO:0030490)3.55530298
39inner mitochondrial membrane organization (GO:0007007)3.54851420
40protein localization to mitochondrion (GO:0070585)3.50734282
41ribonucleoside triphosphate biosynthetic process (GO:0009201)3.49358946
42telomere maintenance via semi-conservative replication (GO:0032201)3.48392342
43regulation of cellular amino acid metabolic process (GO:0006521)3.48118261
44DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.45186236
45sequestering of actin monomers (GO:0042989)3.45052044
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.43691157
47translation (GO:0006412)3.43169393
48pseudouridine synthesis (GO:0001522)3.40770459
49negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.40635415
50negative regulation of ligase activity (GO:0051352)3.40635415
51GTP biosynthetic process (GO:0006183)3.40403433
52protein-cofactor linkage (GO:0018065)3.38319264
53signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.37829259
54intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.37829259
55antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.37754725
56regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.37486061
57mannosylation (GO:0097502)3.37354999
58signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.36855204
59signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.36855204
60signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.36855204
61viral life cycle (GO:0019058)3.33721000
62L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.31811128
63translational initiation (GO:0006413)3.31300495
64metallo-sulfur cluster assembly (GO:0031163)3.30388349
65iron-sulfur cluster assembly (GO:0016226)3.30388349
66base-excision repair, AP site formation (GO:0006285)3.25114108
67respiratory chain complex IV assembly (GO:0008535)3.22790303
68signal transduction involved in DNA damage checkpoint (GO:0072422)3.20052388
69signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20052388
70mitochondrial transport (GO:0006839)3.19563203
71cytochrome complex assembly (GO:0017004)3.18258687
72transcription elongation from RNA polymerase III promoter (GO:0006385)3.18140195
73termination of RNA polymerase III transcription (GO:0006386)3.18140195
74regulation of cellular amine metabolic process (GO:0033238)3.17641601
75anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.16434915
76intracellular protein transmembrane import (GO:0044743)3.16091204
77purine-containing compound salvage (GO:0043101)3.15297244
78signal transduction involved in cell cycle checkpoint (GO:0072395)3.14993725
79cellular protein complex disassembly (GO:0043624)3.14942721
80ribosomal large subunit biogenesis (GO:0042273)3.13890454
81nucleoside triphosphate biosynthetic process (GO:0009142)3.13320628
82nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.13088321
83DNA strand elongation involved in DNA replication (GO:0006271)3.13001887
84GDP-mannose metabolic process (GO:0019673)3.12797327
85water-soluble vitamin biosynthetic process (GO:0042364)3.08644203
86pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.08408169
87antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.07309436
88deoxyribose phosphate biosynthetic process (GO:0046385)3.07065923
892-deoxyribonucleotide biosynthetic process (GO:0009265)3.07065923
90telomere maintenance via recombination (GO:0000722)3.06007714
91DNA strand elongation (GO:0022616)3.05210788
92protein deneddylation (GO:0000338)3.03126393
93Arp2/3 complex-mediated actin nucleation (GO:0034314)3.01241739
94protein maturation by protein folding (GO:0022417)2.99963690
95guanosine-containing compound biosynthetic process (GO:1901070)2.99205214
96regulation of mitochondrial translation (GO:0070129)2.96633926
97oxidative phosphorylation (GO:0006119)2.95053361
98exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.94632971
99cullin deneddylation (GO:0010388)2.91164500
100protein complex biogenesis (GO:0070271)2.90646241
101positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.89618826
102chaperone-mediated protein transport (GO:0072321)2.89429725
103nucleobase-containing small molecule interconversion (GO:0015949)2.89302597
104nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.85443562
105positive regulation of ligase activity (GO:0051351)2.84725514
106rRNA modification (GO:0000154)2.84114852
107ribonucleoprotein complex biogenesis (GO:0022613)2.80358197
108platelet dense granule organization (GO:0060155)2.78067809
1097-methylguanosine mRNA capping (GO:0006370)2.77504440
110mitochondrial respiratory chain complex assembly (GO:0033108)2.74033302
111protein complex disassembly (GO:0043241)2.72660910
112RNA capping (GO:0036260)2.72202153
1137-methylguanosine RNA capping (GO:0009452)2.72202153
114endosome to pigment granule transport (GO:0043485)2.71265826
115endosome to melanosome transport (GO:0035646)2.71265826
116positive regulation of cell cycle arrest (GO:0071158)2.71135132
117amino acid salvage (GO:0043102)2.70710999
118L-methionine salvage (GO:0071267)2.70710999
119L-methionine biosynthetic process (GO:0071265)2.70710999
120cellular component biogenesis (GO:0044085)2.69055581
121cellular response to interferon-beta (GO:0035458)2.68842440
122peptidyl-histidine modification (GO:0018202)2.68401633
123DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.65498246
124protein targeting to membrane (GO:0006612)2.65480543
125spliceosomal snRNP assembly (GO:0000387)2.63935841
126negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.61922672
127deoxyribonucleotide biosynthetic process (GO:0009263)2.61487189
128pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.61315444
129macromolecular complex disassembly (GO:0032984)2.60315378
130NADH dehydrogenase complex assembly (GO:0010257)2.59926219
131mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.59926219
132mitochondrial respiratory chain complex I assembly (GO:0032981)2.59926219
133nuclear-transcribed mRNA catabolic process (GO:0000956)2.56728905

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.05513808
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.80851406
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.56058435
4E2F7_22180533_ChIP-Seq_HELA_Human3.51790500
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.51632044
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.45488619
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.35143493
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.24751545
9ELF1_17652178_ChIP-ChIP_JURKAT_Human3.18123713
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.95624644
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.71216548
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.67054448
13SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.57927273
14IRF8_22096565_ChIP-ChIP_GC-B_Human2.54219985
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.53976295
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51655445
17FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.36750793
18VDR_23849224_ChIP-Seq_CD4+_Human2.32046036
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.30620075
20SRF_21415370_ChIP-Seq_HL-1_Mouse2.30500564
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.27269261
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.24255173
23TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.19200812
24XRN2_22483619_ChIP-Seq_HELA_Human2.13222486
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.10808789
26DCP1A_22483619_ChIP-Seq_HELA_Human2.10567590
27THAP11_20581084_ChIP-Seq_MESCs_Mouse2.01316357
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.00617832
29FOXP3_21729870_ChIP-Seq_TREG_Human1.99227957
30HOXB4_20404135_ChIP-ChIP_EML_Mouse1.95835428
31SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.95829044
32GABP_19822575_ChIP-Seq_HepG2_Human1.92923231
33MYC_19079543_ChIP-ChIP_MESCs_Mouse1.88285639
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.86234776
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.84476041
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81218129
37CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.79356127
38IRF8_21731497_ChIP-ChIP_J774_Mouse1.73827716
39ERG_20887958_ChIP-Seq_HPC-7_Mouse1.72626290
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.71393177
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.70904027
42FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.70686986
43ELK1_19687146_ChIP-ChIP_HELA_Human1.70570377
44YY1_21170310_ChIP-Seq_MESCs_Mouse1.70358729
45MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.68901303
46BP1_19119308_ChIP-ChIP_Hs578T_Human1.63287182
47MYC_18940864_ChIP-ChIP_HL60_Human1.61878684
48SPI1_23547873_ChIP-Seq_NB4_Human1.61710951
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61406452
50TTF2_22483619_ChIP-Seq_HELA_Human1.61139965
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60971040
52CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.49530066
53E2F4_17652178_ChIP-ChIP_JURKAT_Human1.48504343
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.46339001
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.45192231
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.44926179
57STAT4_19710469_ChIP-ChIP_TH1__Mouse1.44523264
58ZNF274_21170338_ChIP-Seq_K562_Hela1.41799755
59CIITA_25753668_ChIP-Seq_RAJI_Human1.39873303
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38448481
61MYB_21317192_ChIP-Seq_ERMYB_Mouse1.35166787
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.34912337
63TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33715567
64SCL_19346495_ChIP-Seq_HPC-7_Human1.33596576
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33546444
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32808290
67MYC_22102868_ChIP-Seq_BL_Human1.30965489
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29207022
69ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.28136953
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.27126088
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26742600
72VDR_21846776_ChIP-Seq_THP-1_Human1.26165388
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.23496982
74BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.23362651
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19432365
76HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.17884990
77MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.17072489
78GATA1_22383799_ChIP-Seq_G1ME_Mouse1.17012749
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16982886
80PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.14273915
81EGR1_19374776_ChIP-ChIP_THP-1_Human1.13916868
82CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.12447615
83CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.11621046
84TFEB_21752829_ChIP-Seq_HELA_Human1.11539266
85POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.10599949
86HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.09696164
87FOXP1_21924763_ChIP-Seq_HESCs_Human1.07945423
88LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07148589
89MYCN_18555785_ChIP-Seq_MESCs_Mouse1.06720031
90TP53_22573176_ChIP-Seq_HFKS_Human1.06162875
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05872362
92NANOG_18555785_ChIP-Seq_MESCs_Mouse1.03349322
93BCL6_27268052_Chip-Seq_Bcells_Human1.03236083
94PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.02903546
95* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.02084440
96ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.02037629
97YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01037687
98LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.00979253
99KDM5A_27292631_Chip-Seq_BREAST_Human1.00945303
100YY1_22570637_ChIP-Seq_MALME-3M_Human1.00259114
101DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99478267
102CTCF_18555785_ChIP-Seq_MESCs_Mouse0.98919492
103MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.98820046
104FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98214678
105VDR_22108803_ChIP-Seq_LS180_Human0.96711679
106SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95560083
107RUNX1_22412390_ChIP-Seq_EML_Mouse0.95293441
108VDR_24763502_ChIP-Seq_THP-1_Human0.95122778
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94345193
110GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94310218
111ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93023597
112PU.1_20513432_ChIP-Seq_Bcells_Mouse0.92837312
113ERG_20517297_ChIP-Seq_VCAP_Human0.92338375
114SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.92051592
115E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.91411319
116E2F1_21310950_ChIP-Seq_MCF-7_Human0.91408904
117CTCF_26484167_Chip-Seq_Bcells_Mouse0.91218637
118SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90985879
119* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.90832274
120ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89334267
121TET1_21451524_ChIP-Seq_MESCs_Mouse0.89061858
122CTCF_20526341_ChIP-Seq_ESCs_Human0.88962748
123ELF1_20517297_ChIP-Seq_JURKAT_Human0.88898401
124IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.87643577
125GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.86846661
126AR_20517297_ChIP-Seq_VCAP_Human0.86027874
127NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.85852577
128NANOG_20526341_ChIP-Seq_ESCs_Human0.85719652
129ERA_21632823_ChIP-Seq_H3396_Human0.84349126
130KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.82084282
131DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.81819676
132TAF2_19829295_ChIP-Seq_ESCs_Human0.77521753
133PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.77358173
134FOXA1_27270436_Chip-Seq_PROSTATE_Human0.76788899

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.24621508
2MP0003693_abnormal_embryo_hatching3.20746551
3MP0003186_abnormal_redox_activity3.15875379
4MP0002396_abnormal_hematopoietic_system2.70683638
5MP0003436_decreased_susceptibility_to2.67477493
6MP0002148_abnormal_hypersensitivity_rea2.59819973
7MP0009785_altered_susceptibility_to2.59097120
8MP0001905_abnormal_dopamine_level2.57434835
9MP0003724_increased_susceptibility_to2.54720361
10MP0005671_abnormal_response_to2.54675769
11MP0003011_delayed_dark_adaptation2.37413935
12MP0001529_abnormal_vocalization2.35303001
13MP0008875_abnormal_xenobiotic_pharmacok2.34241421
14MP0001853_heart_inflammation2.33956904
15MP0002837_dystrophic_cardiac_calcinosis2.31824809
16MP0002653_abnormal_ependyma_morphology2.26832229
17MP0003806_abnormal_nucleotide_metabolis2.25297157
18MP0009333_abnormal_splenocyte_physiolog2.24847288
19MP0003656_abnormal_erythrocyte_physiolo2.22138548
20MP0000685_abnormal_immune_system2.20003480
21MP0003136_yellow_coat_color2.18619959
22MP0001545_abnormal_hematopoietic_system2.17829155
23MP0005397_hematopoietic_system_phenotyp2.17829155
24MP0003763_abnormal_thymus_physiology2.15040408
25MP0005025_abnormal_response_to2.11626943
26MP0005000_abnormal_immune_tolerance2.02313529
27MP0006072_abnormal_retinal_apoptosis1.98959576
28MP0004957_abnormal_blastocyst_morpholog1.93619789
29MP0004808_abnormal_hematopoietic_stem1.87593869
30MP0002132_abnormal_respiratory_system1.86273912
31MP0008995_early_reproductive_senescence1.86126606
32MP0002419_abnormal_innate_immunity1.85529452
33MP0002398_abnormal_bone_marrow1.79630353
34MP0000490_abnormal_crypts_of1.78034717
35MP0002736_abnormal_nociception_after1.77324306
36MP0002723_abnormal_immune_serum1.77097791
37MP0006292_abnormal_olfactory_placode1.76610110
38MP0003718_maternal_effect1.74320361
39MP0010386_abnormal_urinary_bladder1.73815885
40MP0002452_abnormal_antigen_presenting1.73412933
41MP0008789_abnormal_olfactory_epithelium1.73049703
42MP0002420_abnormal_adaptive_immunity1.71741767
43MP0001800_abnormal_humoral_immune1.70522656
44MP0003077_abnormal_cell_cycle1.70363818
45MP0001819_abnormal_immune_cell1.69956218
46MP0006036_abnormal_mitochondrial_physio1.69286082
47MP0005464_abnormal_platelet_physiology1.67940713
48MP0004142_abnormal_muscle_tone1.64125738
49MP0002277_abnormal_respiratory_mucosa1.60918070
50MP0005075_abnormal_melanosome_morpholog1.59292728
51MP0006054_spinal_hemorrhage1.58909720
52MP0002405_respiratory_system_inflammati1.58092443
53MP0010094_abnormal_chromosome_stability1.57356015
54MP0000689_abnormal_spleen_morphology1.56653263
55MP0003195_calcinosis1.56087540
56MP0008058_abnormal_DNA_repair1.54996478
57MP0010030_abnormal_orbit_morphology1.54446849
58MP0000716_abnormal_immune_system1.54045640
59MP0002722_abnormal_immune_system1.53721350
60MP0002429_abnormal_blood_cell1.53531555
61MP0002822_catalepsy1.52446772
62MP0004147_increased_porphyrin_level1.52176283
63MP0008007_abnormal_cellular_replicative1.47988942
64MP0001968_abnormal_touch/_nociception1.45394892
65MP0005551_abnormal_eye_electrophysiolog1.44971824
66MP0003880_abnormal_central_pattern1.44912013
67MP0001845_abnormal_inflammatory_respons1.41392631
68MP0008469_abnormal_protein_level1.40840071
69MP0001533_abnormal_skeleton_physiology1.40425075
70MP0005645_abnormal_hypothalamus_physiol1.39621648
71MP0003111_abnormal_nucleus_morphology1.39104340
72MP0002163_abnormal_gland_morphology1.39061984
73MP0008872_abnormal_physiological_respon1.36531426
74MP0000372_irregular_coat_pigmentation1.35700788
75MP0001790_abnormal_immune_system1.32018594
76MP0005387_immune_system_phenotype1.32018594
77MP0005084_abnormal_gallbladder_morpholo1.30170087
78MP0005332_abnormal_amino_acid1.28575048
79MP0002638_abnormal_pupillary_reflex1.25913908
80MP0005253_abnormal_eye_physiology1.25616227
81MP0002933_joint_inflammation1.23162193
82MP0009697_abnormal_copulation1.22718611
83MP0003786_premature_aging1.22539152
84MP0004133_heterotaxia1.22492334
85MP0005646_abnormal_pituitary_gland1.22301796
86MP0000343_altered_response_to1.20908985
87MP0006276_abnormal_autonomic_nervous1.20644269
88MP0008932_abnormal_embryonic_tissue1.20543924
89MP0006082_CNS_inflammation1.20495092
90MP0003866_abnormal_defecation1.19785417
91MP0000858_altered_metastatic_potential1.18211653
92MP0005058_abnormal_lysosome_morphology1.18061115
93MP0010155_abnormal_intestine_physiology1.16354500
94MP0001873_stomach_inflammation1.15814058
95MP0001986_abnormal_taste_sensitivity1.14981488
96MP0002019_abnormal_tumor_incidence1.13575807
97MP0009379_abnormal_foot_pigmentation1.12440738
98MP0002166_altered_tumor_susceptibility1.11904294
99MP0001764_abnormal_homeostasis1.11614080
100MP0002102_abnormal_ear_morphology1.09866169
101MP0000703_abnormal_thymus_morphology1.08592604
102MP0000313_abnormal_cell_death1.07771947
103MP0005171_absent_coat_pigmentation1.07637750
104MP0001756_abnormal_urination1.06224172
105MP0009764_decreased_sensitivity_to1.05693338
106MP0000631_abnormal_neuroendocrine_gland1.05369806
107MP0002006_tumorigenesis1.04448991
108MP0000465_gastrointestinal_hemorrhage1.03509734
109MP0003943_abnormal_hepatobiliary_system1.03460489
110MP0004782_abnormal_surfactant_physiolog0.96750345
111MP0005174_abnormal_tail_pigmentation0.96150399
112MP0002877_abnormal_melanocyte_morpholog0.94354408
113MP0005410_abnormal_fertilization0.93836570
114MP0005319_abnormal_enzyme/_coenzyme0.93335883
115MP0000681_abnormal_thyroid_gland0.91683734
116MP0009745_abnormal_behavioral_response0.91634306
117MP0001984_abnormal_olfaction0.91262100
118MP0000358_abnormal_cell_content/0.90848518
119MP0000015_abnormal_ear_pigmentation0.89054526
120MP0009046_muscle_twitch0.88994839
121MP0001542_abnormal_bone_strength0.88980940
122MP0000516_abnormal_urinary_system0.87929079
123MP0005367_renal/urinary_system_phenotyp0.87929079
124MP0005390_skeleton_phenotype0.85675251
125MP0002234_abnormal_pharynx_morphology0.85393090
126MP0005636_abnormal_mineral_homeostasis0.85205243
127MP0005379_endocrine/exocrine_gland_phen0.84931387
128MP0003123_paternal_imprinting0.84400380
129MP0009840_abnormal_foam_cell0.84060697
130MP0005499_abnormal_olfactory_system0.83206491
131MP0005394_taste/olfaction_phenotype0.83206491
132MP0003121_genomic_imprinting0.82606210
133MP0002876_abnormal_thyroid_physiology0.81151935
134MP0003279_aneurysm0.81044562
135MP0000538_abnormal_urinary_bladder0.80580656
136MP0000598_abnormal_liver_morphology0.80199452
137MP0006035_abnormal_mitochondrial_morpho0.79516487
138MP0005584_abnormal_enzyme/coenzyme_acti0.79497714
139MP0000750_abnormal_muscle_regeneration0.79183427
140MP0002210_abnormal_sex_determination0.78698234
141MP0001970_abnormal_pain_threshold0.78543729
142MP0000749_muscle_degeneration0.78057717
143MP0005389_reproductive_system_phenotype0.76820943
144MP0002272_abnormal_nervous_system0.76536812
145MP0002282_abnormal_trachea_morphology0.75942089
146MP0004019_abnormal_vitamin_homeostasis0.74810235
147MP0001293_anophthalmia0.74360268
148MP0009643_abnormal_urine_homeostasis0.74286415
149MP0003638_abnormal_response/metabolism_0.73683042
150MP0005360_urolithiasis0.72687293
151MP0002693_abnormal_pancreas_physiology0.71370980
152MP0008877_abnormal_DNA_methylation0.71238278
153MP0001663_abnormal_digestive_system0.69008296
154MP0005377_hearing/vestibular/ear_phenot0.68433631
155MP0003878_abnormal_ear_physiology0.68433631
156MP0002095_abnormal_skin_pigmentation0.67877160
157MP0005423_abnormal_somatic_nervous0.67047205
158MP0002160_abnormal_reproductive_system0.66886721
159MP0001929_abnormal_gametogenesis0.66344896
160MP0005408_hypopigmentation0.66062483
161MP0000026_abnormal_inner_ear0.66001735
162MP0002928_abnormal_bile_duct0.65897461
163MP0008873_increased_physiological_sensi0.65721662
164MP0002938_white_spotting0.65708216
165MP0005083_abnormal_biliary_tract0.64380198
166MP0005365_abnormal_bile_salt0.61193734
167MP0009763_increased_sensitivity_to0.60740358
168MP0008057_abnormal_DNA_replication0.60651272

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)4.47242211
2Abnormality of cells of the erythroid lineage (HP:0012130)4.42778570
3Aplastic anemia (HP:0001915)4.34418966
4Type I transferrin isoform profile (HP:0003642)3.97117440
5Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.79253275
6Decreased activity of mitochondrial respiratory chain (HP:0008972)3.79253275
7Hepatic necrosis (HP:0002605)3.48415692
8Petechiae (HP:0000967)3.43960784
9Hepatocellular necrosis (HP:0001404)3.42616801
10Elevated erythrocyte sedimentation rate (HP:0003565)3.40384204
11Thrombocytosis (HP:0001894)3.38191343
12Mitochondrial inheritance (HP:0001427)3.37383123
13Reticulocytopenia (HP:0001896)3.32873621
14Reduced antithrombin III activity (HP:0001976)3.27865329
15Optic disc pallor (HP:0000543)3.22622276
163-Methylglutaconic aciduria (HP:0003535)3.17148720
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.13726054
18Increased CSF lactate (HP:0002490)3.08504142
19Acute necrotizing encephalopathy (HP:0006965)3.01288127
20Poor head control (HP:0002421)2.98465830
21Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.96152919
22Abnormal protein N-linked glycosylation (HP:0012347)2.96152919
23Abnormal protein glycosylation (HP:0012346)2.96152919
24Abnormal glycosylation (HP:0012345)2.96152919
25Increased hepatocellular lipid droplets (HP:0006565)2.96089775
26Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.89411029
27Abnormality of the heme biosynthetic pathway (HP:0010472)2.88155716
28Abnormal mitochondria in muscle tissue (HP:0008316)2.87435770
29Lipid accumulation in hepatocytes (HP:0006561)2.86606861
30Exertional dyspnea (HP:0002875)2.84087052
31Increased serum lactate (HP:0002151)2.83299499
32Generalized aminoaciduria (HP:0002909)2.82096677
33Increased intramyocellular lipid droplets (HP:0012240)2.80308598
34Congenital, generalized hypertrichosis (HP:0004540)2.79747229
35Renal Fanconi syndrome (HP:0001994)2.77131182
36Abnormality of the anterior horn cell (HP:0006802)2.71198169
37Degeneration of anterior horn cells (HP:0002398)2.71198169
38Emotional lability (HP:0000712)2.68837730
39IgM deficiency (HP:0002850)2.67486973
40Lethargy (HP:0001254)2.65475101
41Methylmalonic aciduria (HP:0012120)2.61911330
42Increased muscle lipid content (HP:0009058)2.58882868
43Lactic acidosis (HP:0003128)2.56590364
44Recurrent abscess formation (HP:0002722)2.55259733
45CNS demyelination (HP:0007305)2.54214909
46Leukodystrophy (HP:0002415)2.51120170
47Pallor (HP:0000980)2.47792432
48Acute encephalopathy (HP:0006846)2.46498570
49Testicular atrophy (HP:0000029)2.46335473
50Medial flaring of the eyebrow (HP:0010747)2.44928117
51Vacuolated lymphocytes (HP:0001922)2.44818165
52Oral leukoplakia (HP:0002745)2.42881422
53Recurrent bacterial skin infections (HP:0005406)2.42749760
54Respiratory difficulties (HP:0002880)2.41606453
55Pancreatic cysts (HP:0001737)2.38563631
56Muscle fiber atrophy (HP:0100295)2.36666997
57Type 2 muscle fiber atrophy (HP:0003554)2.35409488
58Hypothermia (HP:0002045)2.34804383
59Abnormality of dicarboxylic acid metabolism (HP:0010995)2.34800795
60Dicarboxylic aciduria (HP:0003215)2.34800795
61Myositis (HP:0100614)2.32062335
62Vertebral compression fractures (HP:0002953)2.30349293
63Hyperphosphaturia (HP:0003109)2.30332045
64Microretrognathia (HP:0000308)2.29688028
65Abnormality of midbrain morphology (HP:0002418)2.26872557
66Molar tooth sign on MRI (HP:0002419)2.26872557
67Pancytopenia (HP:0001876)2.26275718
68Nausea (HP:0002018)2.23388460
69Methylmalonic acidemia (HP:0002912)2.20984945
70X-linked dominant inheritance (HP:0001423)2.19124067
71True hermaphroditism (HP:0010459)2.18944659
72Exercise intolerance (HP:0003546)2.18489414
73Eczematoid dermatitis (HP:0000976)2.16484189
74Beaking of vertebral bodies (HP:0004568)2.16095546
75Progressive macrocephaly (HP:0004481)2.15298370
76Pancreatic fibrosis (HP:0100732)2.15176304
77Macrocytic anemia (HP:0001972)2.08851241
78Abnormality of T cell physiology (HP:0011840)2.07944246
79Esophageal neoplasm (HP:0100751)2.07459946
80Neoplasm of head and neck (HP:0012288)2.07459946
81Decreased electroretinogram (ERG) amplitude (HP:0000654)2.07417514
82Abnormal pupillary function (HP:0007686)2.06534609
83Aplasia/Hypoplasia of the sacrum (HP:0008517)2.04276061
84Respiratory failure (HP:0002878)2.04254820
85Rough bone trabeculation (HP:0100670)2.03793166
86Purpura (HP:0000979)2.02690766
87Neutropenia (HP:0001875)2.00939658
88Prolonged bleeding time (HP:0003010)1.99456588
89Birth length less than 3rd percentile (HP:0003561)1.99335401
90Optic nerve coloboma (HP:0000588)1.97629612
91Microvesicular hepatic steatosis (HP:0001414)1.97583407
92Delayed CNS myelination (HP:0002188)1.97469323
93Premature graying of hair (HP:0002216)1.90907651
94Congenital stationary night blindness (HP:0007642)1.90412983
95Opisthotonus (HP:0002179)1.89151348
96Irregular epiphyses (HP:0010582)1.87055079
97Increased serum pyruvate (HP:0003542)1.86904189
98Nephrogenic diabetes insipidus (HP:0009806)1.86865563
99Blindness (HP:0000618)1.86803396
100Hyperglycinemia (HP:0002154)1.86147677
101Abnormality of macrophages (HP:0004311)1.85815483
102Aplasia/hypoplasia of the uterus (HP:0008684)1.85768056
103Congenital primary aphakia (HP:0007707)1.85587503
104Abnormality of aromatic amino acid family metabolism (HP:0004338)1.84596471
105Gait imbalance (HP:0002141)1.83303578
106Sclerocornea (HP:0000647)1.79989319
107IgG deficiency (HP:0004315)1.79656909
108Cerebral hypomyelination (HP:0006808)1.79548160
109Abnormality of renal resorption (HP:0011038)1.78765065
110Increased serum ferritin (HP:0003281)1.78449707
111Abnormality of fatty-acid metabolism (HP:0004359)1.78099079
112Cerebral edema (HP:0002181)1.77497265
113Renal tubular dysfunction (HP:0000124)1.76738735
114Autoimmune thrombocytopenia (HP:0001973)1.76255278
115Epistaxis (HP:0000421)1.75065791
11611 pairs of ribs (HP:0000878)1.74301744
117Redundant skin (HP:0001582)1.72906588
118Nonimmune hydrops fetalis (HP:0001790)1.72804634
119Sparse eyelashes (HP:0000653)1.70076576
120Microcytic anemia (HP:0001935)1.69922798
121Concave nail (HP:0001598)1.69786238
122Mediastinal lymphadenopathy (HP:0100721)1.69774950
123Abnormality of T cells (HP:0002843)1.69431608
124Nephronophthisis (HP:0000090)1.69019901
125Type II lissencephaly (HP:0007260)1.67577696
126Glycosuria (HP:0003076)1.67496384
127Abnormality of urine glucose concentration (HP:0011016)1.67496384
128Severe visual impairment (HP:0001141)1.67206949
129Vomiting (HP:0002013)1.67090636
130Orchitis (HP:0100796)1.66816750
131Gliosis (HP:0002171)1.66793039
132Abnormal urine phosphate concentration (HP:0012599)1.66350205
133Recurrent gram-negative bacterial infections (HP:0005420)1.65768209
134Selective tooth agenesis (HP:0001592)1.65706294
135Hypokinesia (HP:0002375)1.64241979
136Biconcave vertebral bodies (HP:0004586)1.63440111
137Prolonged neonatal jaundice (HP:0006579)1.62686852
138Basal ganglia calcification (HP:0002135)1.62635664
139Progressive microcephaly (HP:0000253)1.62271045
140Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.61887997
141Lymphoma (HP:0002665)1.61010924
142Retinal dysplasia (HP:0007973)1.60535239
143Abnormality of glycolysis (HP:0004366)1.57893063
144Amniotic constriction ring (HP:0009775)1.55768776
145Abnormality of placental membranes (HP:0011409)1.55768776

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.67605086
2NME24.14500152
3BUB13.33189624
4PIM23.03739937
5STK162.88946187
6EIF2AK12.76977866
7MAP4K22.64152345
8BCKDK2.34338914
9SIK32.31636569
10EIF2AK32.22510516
11IRAK42.12237746
12KDR1.99506628
13MAP3K121.98318514
14NUAK11.97805758
15TESK21.97519863
16TXK1.93169652
17TESK11.89134193
18ZAP701.87304591
19ERN11.86131468
20MAP4K11.83982372
21ADRBK21.76216384
22VRK11.75013556
23MAP3K111.68379279
24ACVR1B1.67840175
25MUSK1.67173254
26WEE11.58004170
27NME11.56216327
28KIT1.51685902
29BLK1.49529675
30RPS6KA41.47590609
31TGFBR11.47255359
32IRAK31.44591995
33BRSK21.40832897
34DYRK21.40410615
35TBK11.38850672
36CSNK1G31.38140106
37GRK11.36111320
38MYLK1.31851605
39CDK81.30331567
40WNK31.27387755
41ILK1.19446773
42TEC1.18528825
43BTK1.18467437
44ARAF1.17944527
45MAP2K71.16209866
46TSSK61.13806577
47MAP2K31.13246153
48NEK91.12726463
49PLK41.12364067
50IKBKE1.12121846
51MAPKAPK31.08271183
52LIMK11.08166395
53JAK31.07775572
54PDK21.07051745
55ZAK1.06719103
56CSNK1G21.06107994
57LRRK21.06034819
58PIK3CG1.05551964
59TYK21.05042382
60CSNK1G11.02260313
61TRIM281.01994077
62PHKG20.97608298
63PHKG10.97608298
64MAP3K140.97546635
65IKBKB0.96861703
66DYRK30.96256559
67DAPK30.92305264
68ABL20.91679529
69SYK0.91511859
70CCNB10.90998220
71BRSK10.86776351
72FLT30.84723822
73SRPK10.82258704
74CSNK1A1L0.81937500
75BRAF0.81105741
76ADRBK10.81096620
77RPS6KB20.79723253
78MKNK10.79071440
79DAPK10.75619565
80PIM10.75190612
81MAPK150.74746141
82IRAK10.74674362
83MATK0.74617335
84NEK10.74168705
85BMPR1B0.74131291
86GRK70.73871124
87PRKCI0.73307116
88PASK0.72817804
89TAOK30.72716852
90GRK50.71171043
91PLK30.70320706
92FRK0.69734480
93RPS6KA60.68165416
94CDK70.66931599
95LYN0.65949049
96MAPKAPK50.65357859
97EPHB20.65308635
98SCYL20.65288123
99PINK10.64240962
100MST40.64028967
101ATR0.63078595
102EIF2AK20.62907097
103INSRR0.62682241
104LMTK20.61840586
105EPHA20.61074114
106PBK0.60390827
107CAMKK20.58532486
108TLK10.57848251
109RPS6KC10.55590040
110RPS6KL10.55590040
111MAP3K30.55026498
112AURKB0.53738443
113PKN10.51816235
114PRKG20.51446472
115MAP2K60.51379722
116CSNK2A10.51053212
117PAK10.50885132
118PLK10.49289444
119RPS6KA50.49264290
120CSNK2A20.49001744
121CHUK0.48769751
122CDC70.48478480
123AURKA0.47854814
124STK40.47840780
125TGFBR20.45489750
126MAPKAPK20.44933768
127MARK30.44931960
128OXSR10.44753154
129NLK0.44716359
130PAK40.44103335
131MAPK130.44076313
132CDK190.43474302
133TAOK20.43255835
134GRK60.42290688
135PRKCD0.41643577
136EPHA30.41201839
137PRKCG0.38788811
138PRKCE0.38219285
139CSF1R0.38212072
140MAPK40.36836928
141MAP3K40.36345215
142CHEK20.35453395
143DAPK20.34962412
144CSNK1A10.33462503
145PRKCQ0.32535328
146PRKACA0.31405400
147CAMK2G0.29589461
148TIE10.29266277
149WNK40.27253492

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.43178097
2Proteasome_Homo sapiens_hsa030504.35658966
3DNA replication_Homo sapiens_hsa030303.64861623
4RNA polymerase_Homo sapiens_hsa030202.94119620
5Protein export_Homo sapiens_hsa030602.87877590
6Base excision repair_Homo sapiens_hsa034102.54311751
7Mismatch repair_Homo sapiens_hsa034302.50718860
8Pyrimidine metabolism_Homo sapiens_hsa002402.49732399
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.26431327
10Oxidative phosphorylation_Homo sapiens_hsa001902.23923014
11Parkinsons disease_Homo sapiens_hsa050122.23699698
12Cardiac muscle contraction_Homo sapiens_hsa042601.98537595
13Spliceosome_Homo sapiens_hsa030401.97872151
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.96910358
15Fatty acid elongation_Homo sapiens_hsa000621.92760695
16Folate biosynthesis_Homo sapiens_hsa007901.86572486
17Nucleotide excision repair_Homo sapiens_hsa034201.78467314
18Homologous recombination_Homo sapiens_hsa034401.75817027
19Sulfur relay system_Homo sapiens_hsa041221.67603994
20Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.53672020
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53310759
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.49140215
23SNARE interactions in vesicular transport_Homo sapiens_hsa041301.45300555
24Huntingtons disease_Homo sapiens_hsa050161.45013718
25RNA transport_Homo sapiens_hsa030131.35007758
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.33388900
27Collecting duct acid secretion_Homo sapiens_hsa049661.31568090
28Purine metabolism_Homo sapiens_hsa002301.24540793
29RNA degradation_Homo sapiens_hsa030181.23796689
30One carbon pool by folate_Homo sapiens_hsa006701.19815610
31Alzheimers disease_Homo sapiens_hsa050101.18749391
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.18481997
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.17240517
34Legionellosis_Homo sapiens_hsa051341.16712465
35N-Glycan biosynthesis_Homo sapiens_hsa005101.16575613
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14597978
37Asthma_Homo sapiens_hsa053101.09196884
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.07128901
39Other glycan degradation_Homo sapiens_hsa005111.04915644
40Drug metabolism - other enzymes_Homo sapiens_hsa009831.04233017
41Antigen processing and presentation_Homo sapiens_hsa046121.03229337
42Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.03089002
43Cell cycle_Homo sapiens_hsa041101.01731396
44Allograft rejection_Homo sapiens_hsa053301.00393412
45Primary immunodeficiency_Homo sapiens_hsa053400.96816370
46Leishmaniasis_Homo sapiens_hsa051400.96756735
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95886673
48Galactose metabolism_Homo sapiens_hsa000520.95715422
49Glutathione metabolism_Homo sapiens_hsa004800.93567519
50Herpes simplex infection_Homo sapiens_hsa051680.92614147
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.91586651
52Pentose phosphate pathway_Homo sapiens_hsa000300.91214313
53Phototransduction_Homo sapiens_hsa047440.88836339
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.88833524
55Shigellosis_Homo sapiens_hsa051310.87894504
56Propanoate metabolism_Homo sapiens_hsa006400.85990019
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84661344
58Sulfur metabolism_Homo sapiens_hsa009200.84294992
59Measles_Homo sapiens_hsa051620.84288634
60Hematopoietic cell lineage_Homo sapiens_hsa046400.83618522
61Basal transcription factors_Homo sapiens_hsa030220.83228399
62Epstein-Barr virus infection_Homo sapiens_hsa051690.82878626
63Butanoate metabolism_Homo sapiens_hsa006500.80657632
64Non-homologous end-joining_Homo sapiens_hsa034500.80223596
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77916129
66Pyruvate metabolism_Homo sapiens_hsa006200.77082673
67Tryptophan metabolism_Homo sapiens_hsa003800.76864956
68Intestinal immune network for IgA production_Homo sapiens_hsa046720.76576495
69Fanconi anemia pathway_Homo sapiens_hsa034600.76217028
70p53 signaling pathway_Homo sapiens_hsa041150.74670982
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.74664365
72Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74167109
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70958572
74NF-kappa B signaling pathway_Homo sapiens_hsa040640.69834897
75Regulation of autophagy_Homo sapiens_hsa041400.68423491
76Caffeine metabolism_Homo sapiens_hsa002320.68026610
77Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66311851
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65828096
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.65752964
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65432789
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64527970
82Linoleic acid metabolism_Homo sapiens_hsa005910.62993748
83Peroxisome_Homo sapiens_hsa041460.59957147
84Pertussis_Homo sapiens_hsa051330.58145803
85Metabolic pathways_Homo sapiens_hsa011000.57406502
86Apoptosis_Homo sapiens_hsa042100.56922571
87Nitrogen metabolism_Homo sapiens_hsa009100.56820301
88Graft-versus-host disease_Homo sapiens_hsa053320.56209433
89Toll-like receptor signaling pathway_Homo sapiens_hsa046200.55250467
90Selenocompound metabolism_Homo sapiens_hsa004500.54681637
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.52600579
92Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51501515
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.50879521
94Phenylalanine metabolism_Homo sapiens_hsa003600.50588544
95Fructose and mannose metabolism_Homo sapiens_hsa000510.50420702
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49543961
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.49494667
98Rheumatoid arthritis_Homo sapiens_hsa053230.49071565
99Carbon metabolism_Homo sapiens_hsa012000.48055895
100Influenza A_Homo sapiens_hsa051640.47833627
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47553397
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47120075
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47002071
104Lysosome_Homo sapiens_hsa041420.46676859
105Arachidonic acid metabolism_Homo sapiens_hsa005900.45506723
106Phagosome_Homo sapiens_hsa041450.44623695
107Steroid biosynthesis_Homo sapiens_hsa001000.44250853
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44130547
109Biosynthesis of amino acids_Homo sapiens_hsa012300.43923635
110Thyroid cancer_Homo sapiens_hsa052160.43712928
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42818513
112Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42328467
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41005026
114Malaria_Homo sapiens_hsa051440.40496453
115Vibrio cholerae infection_Homo sapiens_hsa051100.39211340
116Hepatitis B_Homo sapiens_hsa051610.39172608
117Autoimmune thyroid disease_Homo sapiens_hsa053200.37982424
118Type I diabetes mellitus_Homo sapiens_hsa049400.37436050
119Chemical carcinogenesis_Homo sapiens_hsa052040.36494063
120Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36266077
121Steroid hormone biosynthesis_Homo sapiens_hsa001400.36161459
122Tyrosine metabolism_Homo sapiens_hsa003500.36012838
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35597917
124Jak-STAT signaling pathway_Homo sapiens_hsa046300.35505039
125beta-Alanine metabolism_Homo sapiens_hsa004100.35320098
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35016677
127Acute myeloid leukemia_Homo sapiens_hsa052210.33853471
128Tuberculosis_Homo sapiens_hsa051520.33535055
129Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32343048
130Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30694970
131Systemic lupus erythematosus_Homo sapiens_hsa053220.30589161
132Synaptic vesicle cycle_Homo sapiens_hsa047210.29844092
133Fatty acid degradation_Homo sapiens_hsa000710.28881701
134Ether lipid metabolism_Homo sapiens_hsa005650.28249505
135Mineral absorption_Homo sapiens_hsa049780.27774986

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