WASH5P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of histone H3-K27 methylation (GO:0061085)4.63295947
2negative regulation of erythrocyte differentiation (GO:0045647)4.62096982
3mannose metabolic process (GO:0006013)4.50726104
4histone H3-K36 demethylation (GO:0070544)4.31974543
5positive regulation of gamma-delta T cell activation (GO:0046645)4.06560601
6histone H3-K4 trimethylation (GO:0080182)4.03742968
7regulation of gamma-delta T cell differentiation (GO:0045586)3.95057072
8positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.80622306
9regulation of gamma-delta T cell activation (GO:0046643)3.70199859
10histone lysine demethylation (GO:0070076)3.64023025
11negative regulation of myotube differentiation (GO:0010832)3.61562985
12histone H3-K4 methylation (GO:0051568)3.59982628
13histone H3-K9 demethylation (GO:0033169)3.58656663
14regulation of RNA export from nucleus (GO:0046831)3.49890755
15histone demethylation (GO:0016577)3.47592954
16monoubiquitinated protein deubiquitination (GO:0035520)3.42142149
17embryonic process involved in female pregnancy (GO:0060136)3.36130816
18positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.29571031
19definitive hemopoiesis (GO:0060216)3.25900126
20dosage compensation (GO:0007549)3.25472737
21nuclear pore complex assembly (GO:0051292)3.25081315
22glucocorticoid receptor signaling pathway (GO:0042921)3.24269780
23response to muramyl dipeptide (GO:0032495)3.23312547
24regulation of nucleobase-containing compound transport (GO:0032239)3.17227229
25histone H3-K9 modification (GO:0061647)3.14479573
26histone lysine methylation (GO:0034968)3.12529969
27positive regulation of CREB transcription factor activity (GO:0032793)3.11439276
28regulation of NFAT protein import into nucleus (GO:0051532)3.09007624
29cytoplasmic mRNA processing body assembly (GO:0033962)3.03667907
30intracellular estrogen receptor signaling pathway (GO:0030520)3.03363684
31negative regulation of histone methylation (GO:0031061)3.02785336
32corticosteroid receptor signaling pathway (GO:0031958)3.02595128
33positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.02491742
34thymic T cell selection (GO:0045061)3.02329864
35regulation of ARF protein signal transduction (GO:0032012)3.02013618
36positive regulation of granulocyte differentiation (GO:0030854)3.02003158
37negative thymic T cell selection (GO:0045060)3.00643808
38protein dealkylation (GO:0008214)2.99284860
39protein demethylation (GO:0006482)2.99284860
40cellular response to ethanol (GO:0071361)2.97454590
41B cell receptor signaling pathway (GO:0050853)2.93314054
42positive thymic T cell selection (GO:0045059)2.92880051
43regulation of necroptotic process (GO:0060544)2.90793260
44insulin-like growth factor receptor signaling pathway (GO:0048009)2.84587247
45negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.83172741
46negative T cell selection (GO:0043383)2.80821516
47positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.80677085
48positive T cell selection (GO:0043368)2.78771583
49histone H3-K9 methylation (GO:0051567)2.78701844
50iron ion import (GO:0097286)2.78640803
51T cell selection (GO:0045058)2.77898366
52regulation of ARF GTPase activity (GO:0032312)2.73650108
53positive regulation of histone deacetylation (GO:0031065)2.73475824
54stress granule assembly (GO:0034063)2.71985392
55response to laminar fluid shear stress (GO:0034616)2.70623748
56peptidyl-lysine trimethylation (GO:0018023)2.69533315
57positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.68831101
58histone H4 deacetylation (GO:0070933)2.68320513
593-UTR-mediated mRNA stabilization (GO:0070935)2.68189975
60peptidyl-lysine methylation (GO:0018022)2.66301715
61antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.65586025
62germinal center formation (GO:0002467)2.63001975
63cell-substrate adherens junction assembly (GO:0007045)2.62196503
64focal adhesion assembly (GO:0048041)2.62196503
65phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.61959589
66peptidyl-lysine dimethylation (GO:0018027)2.61518429
67nuclear pore organization (GO:0006999)2.59355946
68striated muscle atrophy (GO:0014891)2.57056149
69regulation of B cell receptor signaling pathway (GO:0050855)2.56439723
70negative regulation of cell killing (GO:0031342)2.55720840
71negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.55720840
72adherens junction assembly (GO:0034333)2.55545652
73histone methylation (GO:0016571)2.54996535
74pre-miRNA processing (GO:0031054)2.53805313
75negative regulation of fatty acid transport (GO:2000192)2.51523529
76protein K48-linked deubiquitination (GO:0071108)2.50726297
77positive regulation of protein deacetylation (GO:0090312)2.49912380
78antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.49785853
79mRNA stabilization (GO:0048255)2.49753913
80RNA stabilization (GO:0043489)2.49753913
81positive regulation of protein import into nucleus, translocation (GO:0033160)2.47258574
82regulation of chromatin binding (GO:0035561)2.46916573
83histone H3 deacetylation (GO:0070932)2.46305325
84mucosal-associated lymphoid tissue development (GO:0048537)2.45391577
85Peyers patch development (GO:0048541)2.45391577
86negative regulation of gene expression, epigenetic (GO:0045814)2.45201337
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.44916793
88regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.44110208
89negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.43744747
90skeletal muscle adaptation (GO:0043501)2.43425229
91response to epidermal growth factor (GO:0070849)2.43116374
92regulation of histone H3-K4 methylation (GO:0051569)2.42945599
93positive regulation of gene expression, epigenetic (GO:0045815)2.42478615
94peptidyl-threonine phosphorylation (GO:0018107)2.42054255
95face development (GO:0060324)2.41229754
96histone H4-K16 acetylation (GO:0043984)2.41076752
97antigen processing and presentation of endogenous antigen (GO:0019883)2.38485881
98coronary vasculature morphogenesis (GO:0060977)2.35658171
99regulation of type I interferon-mediated signaling pathway (GO:0060338)2.35322612
100endothelial cell chemotaxis (GO:0035767)2.32472856

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_22102868_ChIP-Seq_BL_Human3.90077071
2VDR_21846776_ChIP-Seq_THP-1_Human3.21321716
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.17232665
4TCF7_22412390_ChIP-Seq_EML_Mouse2.93342617
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.89321695
6KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.87275697
7KDM2B_26808549_Chip-Seq_SUP-B15_Human2.86463825
8EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.57336178
9KDM2B_26808549_Chip-Seq_DND41_Human2.56871305
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.55433669
11KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.47854019
12SCL_19346495_ChIP-Seq_HPC-7_Human2.46765690
13VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.36327901
14* MAF_26560356_Chip-Seq_TH1_Human2.25769907
15LXR_22292898_ChIP-Seq_THP-1_Human2.13547942
16GATA1_19941826_ChIP-Seq_K562_Human2.10759842
17ELK3_25401928_ChIP-Seq_HUVEC_Human2.10108868
18IRF8_22096565_ChIP-ChIP_GC-B_Human2.09267471
19VDR_24763502_ChIP-Seq_THP-1_Human2.04988652
20TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03308459
21KDM2B_26808549_Chip-Seq_JURKAT_Human2.02901558
22UTX_26944678_Chip-Seq_JUKART_Human2.01507433
23E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.00142472
24MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.97919328
25TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.97881691
26GATA1_22025678_ChIP-Seq_K562_Human1.93265765
27KDM2B_26808549_Chip-Seq_K562_Human1.89503497
28* SPI1_23127762_ChIP-Seq_K562_Human1.88846452
29* MAF_26560356_Chip-Seq_TH2_Human1.88601625
30GATA1_19941827_ChIP-Seq_MEL_Mouse1.82944905
31NCOR1_26117541_ChIP-Seq_K562_Human1.77937182
32TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.72772385
33RACK7_27058665_Chip-Seq_MCF-7_Human1.72271633
34* RUNX1_27514584_Chip-Seq_MCF-7_Human1.71921799
35FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.71119017
36SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.69864829
37GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.64453429
38* MYB_26560356_Chip-Seq_TH1_Human1.62421321
39CIITA_25753668_ChIP-Seq_RAJI_Human1.61150580
40RUNX_20019798_ChIP-Seq_JUKART_Human1.59964618
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.59076488
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.57323600
43NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56246758
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.55103189
45DROSHA_22980978_ChIP-Seq_HELA_Human1.54528490
46THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.51877343
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.51305285
48GATA2_19941826_ChIP-Seq_K562_Human1.48560905
49PKCTHETA_26484144_Chip-Seq_BREAST_Human1.46739668
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.45618769
51MYB_26560356_Chip-Seq_TH2_Human1.45103579
52ESR2_21235772_ChIP-Seq_MCF-7_Human1.44745358
53DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.43972910
54EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.43350011
55CREB1_26743006_Chip-Seq_LNCaP_Human1.42835099
56* SMC4_20622854_ChIP-Seq_HELA_Human1.42602868
57ZFP281_27345836_Chip-Seq_ESCs_Mouse1.39355087
58CTCF_27219007_Chip-Seq_ERYTHROID_Human1.37325360
59MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.37108335
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.35370776
61FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.35366236
62MYB_21317192_ChIP-Seq_ERMYB_Mouse1.33883786
63CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.30719689
64KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.30685701
65P300_27058665_Chip-Seq_ZR-75-30cells_Human1.28600202
66CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.28341498
67SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28253473
68KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.25006861
69RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23958742
70P68_20966046_ChIP-Seq_HELA_Human1.23364946
71NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.21951965
72NFIB_24661679_ChIP-Seq_LUNG_Mouse1.21771643
73GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20930360
74ESR1_20079471_ChIP-ChIP_T-47D_Human1.19689089
75RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.18924201
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.18396896
77GATA1_22383799_ChIP-Seq_G1ME_Mouse1.16330515
78STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.16041796
79WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.14673208
80TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.10459492
81CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08925014
82ZFP281_18757296_ChIP-ChIP_E14_Mouse1.07230032
83SA1_27219007_Chip-Seq_ERYTHROID_Human1.06405703
84EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.05476911
85FOXA2_19822575_ChIP-Seq_HepG2_Human1.04360248
86E2F7_22180533_ChIP-Seq_HELA_Human1.04177361
87SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04123515
88ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03612041
89ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02176519
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01014429
91RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.00592111
92SMAD_19615063_ChIP-ChIP_OVARY_Human0.98816011
93GATA3_27048872_Chip-Seq_THYMUS_Human0.98740296
94MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.98087592
95STAT4_19710469_ChIP-ChIP_TH1__Mouse0.96962579
96CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95621269
97CLOCK_20551151_ChIP-Seq_293T_Human0.94674006
98GATA2_22383799_ChIP-Seq_G1ME_Mouse0.93194766
99RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92863849
100IRF8_27001747_Chip-Seq_BMDM_Mouse0.90908591

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005076_abnormal_cell_differentiation3.56381586
2MP0003705_abnormal_hypodermis_morpholog3.08245709
3MP0008057_abnormal_DNA_replication2.97657220
4MP0002009_preneoplasia2.94352211
5MP0003763_abnormal_thymus_physiology2.85274939
6MP0002396_abnormal_hematopoietic_system2.68493246
7MP0005451_abnormal_body_composition2.54937843
8MP0009278_abnormal_bone_marrow2.43471594
9MP0003436_decreased_susceptibility_to2.32909736
10MP0004808_abnormal_hematopoietic_stem2.07686638
11MP0005409_darkened_coat_color2.03554389
12MP0003656_abnormal_erythrocyte_physiolo2.00847847
13MP0004947_skin_inflammation1.97795338
14MP0008961_abnormal_basal_metabolism1.96010550
15MP0003091_abnormal_cell_migration1.84515004
16MP0003300_gastrointestinal_ulcer1.82224692
17MP0004381_abnormal_hair_follicle1.79185747
18MP0004264_abnormal_extraembryonic_tissu1.76731756
19MP0003303_peritoneal_inflammation1.75578517
20MP0003045_fibrosis1.75470620
21MP0003172_abnormal_lysosome_physiology1.72942320
22MP0001800_abnormal_humoral_immune1.72387751
23MP0000703_abnormal_thymus_morphology1.70576212
24MP0001545_abnormal_hematopoietic_system1.68666658
25MP0005397_hematopoietic_system_phenotyp1.68666658
26MP0001873_stomach_inflammation1.65263620
27MP0001835_abnormal_antigen_presentation1.65210495
28MP0008260_abnormal_autophagy1.64658747
29MP0002398_abnormal_bone_marrow1.64537131
30MP0000685_abnormal_immune_system1.58014363
31MP0004185_abnormal_adipocyte_glucose1.57879232
32MP0004130_abnormal_muscle_cell1.51353283
33MP0002166_altered_tumor_susceptibility1.49634553
34MP0002249_abnormal_larynx_morphology1.45750194
35MP0000733_abnormal_muscle_development1.43130469
36MP0009115_abnormal_fat_cell1.42134925
37MP0005083_abnormal_biliary_tract1.41598659
38MP0005666_abnormal_adipose_tissue1.40971867
39MP0004233_abnormal_muscle_weight1.39332098
40MP0001348_abnormal_lacrimal_gland1.38798745
41MP0002722_abnormal_immune_system1.36470452
42MP0002405_respiratory_system_inflammati1.33016947
43MP0002420_abnormal_adaptive_immunity1.27574399
44MP0000716_abnormal_immune_system1.27405008
45MP0001819_abnormal_immune_cell1.27003997
46MP0001790_abnormal_immune_system1.24082611
47MP0005387_immune_system_phenotype1.24082611
48MP0002723_abnormal_immune_serum1.23909543
49MP0005621_abnormal_cell_physiology1.22211164
50MP0002419_abnormal_innate_immunity1.21980719
51MP0005025_abnormal_response_to1.20727526
52MP0000689_abnormal_spleen_morphology1.19785734
53MP0002452_abnormal_antigen_presenting1.19758233
54MP0005375_adipose_tissue_phenotype1.19411054
55MP0003828_pulmonary_edema1.16570942
56MP0001849_ear_inflammation1.16312232
57MP0000003_abnormal_adipose_tissue1.15154988
58MP0002429_abnormal_blood_cell1.14503167
59MP0002933_joint_inflammation1.14347396
60MP0010155_abnormal_intestine_physiology1.13533255
61MP0003866_abnormal_defecation1.12255879
62MP0000678_abnormal_parathyroid_gland1.10308281
63MP0010307_abnormal_tumor_latency1.10243056
64MP0003566_abnormal_cell_adhesion1.08949643
65MP0005000_abnormal_immune_tolerance1.08101452
66MP0005058_abnormal_lysosome_morphology1.06685457
67MP0003453_abnormal_keratinocyte_physiol1.03335562
68MP0010630_abnormal_cardiac_muscle1.03196829
69MP0008995_early_reproductive_senescence1.02826192
70MP0003111_abnormal_nucleus_morphology0.99249274
71MP0002970_abnormal_white_adipose0.97938026
72MP0000858_altered_metastatic_potential0.97920091
73MP0002998_abnormal_bone_remodeling0.96822131
74MP0005310_abnormal_salivary_gland0.93321558
75MP0002086_abnormal_extraembryonic_tissu0.93027730
76MP0001851_eye_inflammation0.92539935
77MP0004858_abnormal_nervous_system0.90142825
78MP0003984_embryonic_growth_retardation0.89048751
79MP0002877_abnormal_melanocyte_morpholog0.88032900
80MP0009931_abnormal_skin_appearance0.87480767
81MP0003115_abnormal_respiratory_system0.85684675
82MP0004197_abnormal_fetal_growth/weight/0.83978534
83MP0003690_abnormal_glial_cell0.83250026
84MP0002088_abnormal_embryonic_growth/wei0.82805870
85MP0005670_abnormal_white_adipose0.82101392
86MP0002925_abnormal_cardiovascular_devel0.81382929
87MP0003221_abnormal_cardiomyocyte_apopto0.81342660
88MP0006138_congestive_heart_failure0.79720526
89MP0009333_abnormal_splenocyte_physiolog0.79283606
90MP0004043_abnormal_pH_regulation0.79236875
91MP0002019_abnormal_tumor_incidence0.78592323
92MP0000759_abnormal_skeletal_muscle0.75597260
93MP0010352_gastrointestinal_tract_polyps0.75525414
94MP0000350_abnormal_cell_proliferation0.73972979
95MP0002971_abnormal_brown_adipose0.73613418
96MP0004087_abnormal_muscle_fiber0.72863495
97MP0001915_intracranial_hemorrhage0.70809912
98MP0001730_embryonic_growth_arrest0.70633436
99MP0005671_abnormal_response_to0.70403823
100MP0002168_other_aberrant_phenotype0.69866378

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)5.21251203
2Dysmetric saccades (HP:0000641)3.74971764
3Colitis (HP:0002583)3.39586700
4Broad face (HP:0000283)3.21585053
5Genetic anticipation (HP:0003743)3.18089457
6Obstructive sleep apnea (HP:0002870)2.99176918
7Eczematoid dermatitis (HP:0000976)2.78867990
8Long eyelashes (HP:0000527)2.72020829
9Sparse lateral eyebrow (HP:0005338)2.65741912
10Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.52984223
11Lip pit (HP:0100267)2.51497223
12Ankyloglossia (HP:0010296)2.48885535
13Hyperacusis (HP:0010780)2.47820362
14Dislocated radial head (HP:0003083)2.44426625
15Persistence of primary teeth (HP:0006335)2.42099900
16Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.35694417
17Cerebral aneurysm (HP:0004944)2.35639185
18Gastrointestinal inflammation (HP:0004386)2.32514920
19Flat acetabular roof (HP:0003180)2.27728841
20Inflammation of the large intestine (HP:0002037)2.26373452
21Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.24430997
22Narrow palate (HP:0000189)2.23213438
23Abnormality of the radial head (HP:0003995)2.22825508
24Hemorrhage of the eye (HP:0011885)2.21832465
25Heterotopia (HP:0002282)2.20463598
26Abnormality of the columella (HP:0009929)2.19074639
27Neonatal hypoglycemia (HP:0001998)2.13046240
28Sandal gap (HP:0001852)2.11563430
29Bowel incontinence (HP:0002607)2.10345486
30Reticulocytosis (HP:0001923)2.06365873
31Metaphyseal cupping (HP:0003021)2.05113347
32Urethral obstruction (HP:0000796)2.03481249
33Slow saccadic eye movements (HP:0000514)2.02893126
34Increased IgE level (HP:0003212)2.02167491
35Onion bulb formation (HP:0003383)1.97449754
36Disproportionate tall stature (HP:0001519)1.97141083
37Abnormal delayed hypersensitivity skin test (HP:0002963)1.96671515
38Germ cell neoplasia (HP:0100728)1.95608332
39Cellulitis (HP:0100658)1.95473760
40Aneurysm (HP:0002617)1.93480631
41Abnormality of oral frenula (HP:0000190)1.92933121
42Gingivitis (HP:0000230)1.90854195
43Recurrent viral infections (HP:0004429)1.90299496
44Spinal cord lesions (HP:0100561)1.90189090
45Syringomyelia (HP:0003396)1.90189090
46Prominent nose (HP:0000448)1.89513737
47Pustule (HP:0200039)1.89500469
48Aortic aneurysm (HP:0004942)1.89135077
49Distal lower limb amyotrophy (HP:0008944)1.87283418
50Thin bony cortex (HP:0002753)1.86911531
51Polycythemia (HP:0001901)1.86157725
52Abnormal large intestine physiology (HP:0012700)1.85189025
53Anal stenosis (HP:0002025)1.85034447
54Recurrent fungal infections (HP:0002841)1.84775602
55Spontaneous hematomas (HP:0007420)1.84315032
56Macroorchidism (HP:0000053)1.83337312
57Seborrheic dermatitis (HP:0001051)1.82807913
58Acute myeloid leukemia (HP:0004808)1.81989774
59Gastrointestinal infarctions (HP:0005244)1.79843404
60Abnormality of the thoracic spine (HP:0100711)1.77506706
61Viral hepatitis (HP:0006562)1.76702605
62Truncal obesity (HP:0001956)1.73733004
63Centrally nucleated skeletal muscle fibers (HP:0003687)1.72646500
64Prolonged bleeding time (HP:0003010)1.72320378
65Panhypogammaglobulinemia (HP:0003139)1.70445610
66Broad palm (HP:0001169)1.69785080
67Asymmetry of the thorax (HP:0001555)1.67599358
68Bronchomalacia (HP:0002780)1.64448211
69Neoplasm of the heart (HP:0100544)1.64441611
70Ulnar bowing (HP:0003031)1.63927179
71Interstitial pulmonary disease (HP:0006530)1.63334098
72Ureteral stenosis (HP:0000071)1.63191768
73Clumsiness (HP:0002312)1.61534754
74Tapered finger (HP:0001182)1.61148043
75Ureteral obstruction (HP:0006000)1.61127634
76Abnormality of the distal phalanx of the thumb (HP:0009617)1.59899781
77Pointed chin (HP:0000307)1.59580513
78Obsessive-compulsive behavior (HP:0000722)1.59257737
79Thin ribs (HP:0000883)1.58980746
80Vertebral arch anomaly (HP:0008438)1.58680394
81Chronic mucocutaneous candidiasis (HP:0002728)1.56747584
82Recurrent cutaneous fungal infections (HP:0011370)1.56747584
83Increased cerebral lipofuscin (HP:0011813)1.56395932
84Segmental peripheral demyelination/remyelination (HP:0003481)1.56220593
85Papilledema (HP:0001085)1.55110601
86Mitral valve prolapse (HP:0001634)1.54255728
87Thick eyebrow (HP:0000574)1.52546658
88Long palpebral fissure (HP:0000637)1.52542116
89Increased neuronal autofluorescent lipopigment (HP:0002074)1.52128657
90Tented upper lip vermilion (HP:0010804)1.51945364
91Subacute progressive viral hepatitis (HP:0006572)1.49733813
92Recurrent bacterial skin infections (HP:0005406)1.48762239
93Basal cell carcinoma (HP:0002671)1.48460648
94Agammaglobulinemia (HP:0004432)1.48166229
95Protruding tongue (HP:0010808)1.46911276
96Epistaxis (HP:0000421)1.45956553
97Exercise-induced myalgia (HP:0003738)1.45906793
98Increased connective tissue (HP:0009025)1.45669145
99Self-mutilation (HP:0000742)1.44393800
100Progressive cerebellar ataxia (HP:0002073)1.43741234

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.50658990
2CDK124.33626776
3ICK3.06604445
4EEF2K2.92850769
5PRPF4B2.75686389
6AKT32.33901927
7BRD42.17250101
8FGFR42.03895225
9MAP3K102.00914424
10RIPK41.99746165
11SIK21.88135931
12PKN21.86536475
13SIK11.83595731
14ERN11.82924450
15BLK1.74976636
16MAP4K11.68915379
17CDC42BPA1.67410498
18MAP3K71.63600852
19SMG11.58500190
20MARK21.56603289
21MAP2K31.56547221
22CAMK1D1.56308478
23MTOR1.44325968
24MAP3K131.43103962
25FGFR31.35088808
26ZAP701.29969130
27MAP3K61.28979932
28MAP3K141.23249328
29RIPK11.21900130
30TYK21.20996990
31MAPK111.20814835
32TTN1.17590133
33BTK1.16206488
34RET1.14285893
35KSR21.10182887
36CAMK1G1.09614310
37TNK21.09154818
38PDGFRA1.07517948
39EPHB11.06213757
40JAK11.01526218
41TRPM70.94123464
42WNK10.93221006
43GRK60.91720504
44CDK40.91252634
45EPHA30.89071666
46TAOK30.88057066
47CDK60.82402281
48JAK30.81719123
49SGK30.81200139
50PRKD20.80908721
51HIPK20.79119406
52HCK0.78808083
53MAPK120.77383072
54CAMKK10.76829318
55MELK0.76064820
56JAK20.74132231
57SGK20.70278119
58TYRO30.69607804
59STK380.67482569
60BMX0.66932241
61PTK60.66712171
62NEK60.65262345
63SYK0.64177785
64MAPK70.63913780
65PDPK10.63720187
66MST1R0.63529659
67PDK10.61357507
68PRKAA10.60397368
69PDGFRB0.60213193
70FES0.59964925
71PRKAA20.59335863
72LATS10.58665077
73ITK0.58103380
74RPS6KA20.56427830
75MAPK150.55896069
76MAP3K20.55388436
77RPS6KL10.54701648
78RPS6KC10.54701648
79LCK0.54424134
80MAPK100.53390161
81MAP3K10.52018879
82SIK30.51663562
83SGK2230.50430983
84SGK4940.50430983
85CSK0.50330433
86NLK0.50305396
87CAMK40.49916035
88IKBKE0.49419670
89RPS6KA60.46411372
90CHUK0.46139663
91MAP2K20.45821607
92MAPK80.44722311
93IRAK40.44417801
94MAPK30.42787232
95RAF10.42477391
96MAPK10.40341758
97MARK30.39254435
98TBK10.37535443
99YES10.36934109
100SGK10.36391362

Predicted pathways (KEGG)

RankGene SetZ-score
1Acute myeloid leukemia_Homo sapiens_hsa052212.14800656
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.03842993
3Chronic myeloid leukemia_Homo sapiens_hsa052201.94602986
4Non-small cell lung cancer_Homo sapiens_hsa052231.93457849
5B cell receptor signaling pathway_Homo sapiens_hsa046621.90107489
6Lysine degradation_Homo sapiens_hsa003101.73785091
7Other glycan degradation_Homo sapiens_hsa005111.67786532
8Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.65610518
9mTOR signaling pathway_Homo sapiens_hsa041501.63659753
10Phosphatidylinositol signaling system_Homo sapiens_hsa040701.58252336
11Pancreatic cancer_Homo sapiens_hsa052121.53730238
12VEGF signaling pathway_Homo sapiens_hsa043701.50941440
13Notch signaling pathway_Homo sapiens_hsa043301.45339491
14AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.40660235
15Choline metabolism in cancer_Homo sapiens_hsa052311.40164139
16Osteoclast differentiation_Homo sapiens_hsa043801.38983700
17Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.36838700
18T cell receptor signaling pathway_Homo sapiens_hsa046601.31234756
19Endometrial cancer_Homo sapiens_hsa052131.30642276
20Renal cell carcinoma_Homo sapiens_hsa052111.28249110
21Inositol phosphate metabolism_Homo sapiens_hsa005621.27729082
22Thyroid hormone signaling pathway_Homo sapiens_hsa049191.25740671
23Type II diabetes mellitus_Homo sapiens_hsa049301.23783341
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.23264868
25ErbB signaling pathway_Homo sapiens_hsa040121.23188361
26Prolactin signaling pathway_Homo sapiens_hsa049171.22505633
27Neurotrophin signaling pathway_Homo sapiens_hsa047221.21875262
28Hepatitis B_Homo sapiens_hsa051611.19826834
29Prostate cancer_Homo sapiens_hsa052151.17485231
30Phospholipase D signaling pathway_Homo sapiens_hsa040721.16930951
31Glioma_Homo sapiens_hsa052141.16008044
32Longevity regulating pathway - mammal_Homo sapiens_hsa042111.15812144
33FoxO signaling pathway_Homo sapiens_hsa040681.13314773
34Insulin resistance_Homo sapiens_hsa049311.10093970
35Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.10056765
36MicroRNAs in cancer_Homo sapiens_hsa052061.09871611
37Colorectal cancer_Homo sapiens_hsa052101.08600842
38Influenza A_Homo sapiens_hsa051641.07915471
39TNF signaling pathway_Homo sapiens_hsa046681.07592519
40GnRH signaling pathway_Homo sapiens_hsa049121.07526381
41Adipocytokine signaling pathway_Homo sapiens_hsa049201.05921365
42Hepatitis C_Homo sapiens_hsa051601.05797915
43Insulin signaling pathway_Homo sapiens_hsa049101.04800976
44Leishmaniasis_Homo sapiens_hsa051401.04686619
45Jak-STAT signaling pathway_Homo sapiens_hsa046301.02991170
46Toxoplasmosis_Homo sapiens_hsa051451.02953050
47Platelet activation_Homo sapiens_hsa046111.00608198
48Measles_Homo sapiens_hsa051620.98588168
49Thyroid cancer_Homo sapiens_hsa052160.94301676
50Toll-like receptor signaling pathway_Homo sapiens_hsa046200.94072305
51Small cell lung cancer_Homo sapiens_hsa052220.93491588
52ABC transporters_Homo sapiens_hsa020100.93428049
53RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.91798923
54Estrogen signaling pathway_Homo sapiens_hsa049150.90920067
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90000743
56Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89787386
57Herpes simplex infection_Homo sapiens_hsa051680.88612390
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.88590682
59Bladder cancer_Homo sapiens_hsa052190.88461874
60Viral carcinogenesis_Homo sapiens_hsa052030.88223464
61AMPK signaling pathway_Homo sapiens_hsa041520.84898942
62HIF-1 signaling pathway_Homo sapiens_hsa040660.84292902
63Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84201289
64Central carbon metabolism in cancer_Homo sapiens_hsa052300.83947712
65Apoptosis_Homo sapiens_hsa042100.81901806
66Fructose and mannose metabolism_Homo sapiens_hsa000510.81297750
67Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79898942
68Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79849749
69mRNA surveillance pathway_Homo sapiens_hsa030150.79825596
70Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77619032
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.77596892
72Primary immunodeficiency_Homo sapiens_hsa053400.76689415
73Adherens junction_Homo sapiens_hsa045200.76159085
74Long-term potentiation_Homo sapiens_hsa047200.74900546
75HTLV-I infection_Homo sapiens_hsa051660.73575928
76NOD-like receptor signaling pathway_Homo sapiens_hsa046210.72784829
77Dorso-ventral axis formation_Homo sapiens_hsa043200.71912680
78Chemokine signaling pathway_Homo sapiens_hsa040620.70607950
79Tuberculosis_Homo sapiens_hsa051520.70431620
80Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70236880
81Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69678690
82Focal adhesion_Homo sapiens_hsa045100.67831873
83Staphylococcus aureus infection_Homo sapiens_hsa051500.66632551
84Proteoglycans in cancer_Homo sapiens_hsa052050.65261267
85MAPK signaling pathway_Homo sapiens_hsa040100.62405928
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.60423500
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.56906696
88Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.56828491
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54855930
90Cholinergic synapse_Homo sapiens_hsa047250.54100848
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.49897151
92Epstein-Barr virus infection_Homo sapiens_hsa051690.49333165
93Malaria_Homo sapiens_hsa051440.48533786
94Glycerophospholipid metabolism_Homo sapiens_hsa005640.48184287
95Pathways in cancer_Homo sapiens_hsa052000.46270818
96Circadian rhythm_Homo sapiens_hsa047100.45992708
97Endocytosis_Homo sapiens_hsa041440.44815835
98Rap1 signaling pathway_Homo sapiens_hsa040150.44503838
99Viral myocarditis_Homo sapiens_hsa054160.44212064
100Amoebiasis_Homo sapiens_hsa051460.41727072

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »