VSTM5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)4.94495800
2cellular response to ATP (GO:0071318)4.72252302
3neuronal action potential propagation (GO:0019227)4.69856527
4negative regulation of dendrite morphogenesis (GO:0050774)4.64865412
5vocalization behavior (GO:0071625)4.62525260
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.60884963
7cell migration in hindbrain (GO:0021535)4.57261867
8behavioral response to nicotine (GO:0035095)4.53070552
9negative regulation of cell aging (GO:0090344)4.46553625
10regulation of skeletal muscle contraction (GO:0014819)4.45971744
11phosphate ion transport (GO:0006817)4.45174355
12glutamate secretion (GO:0014047)4.42688167
13phosphate ion transmembrane transport (GO:0035435)4.42107392
14neuron cell-cell adhesion (GO:0007158)4.41524848
15protein localization to synapse (GO:0035418)4.38288622
16neuromuscular synaptic transmission (GO:0007274)4.36024845
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.33230077
18regulation of synaptic vesicle exocytosis (GO:2000300)4.25061587
19detection of temperature stimulus involved in sensory perception of pain (GO:0050965)4.17273051
20detection of temperature stimulus involved in sensory perception (GO:0050961)4.17273051
21sensory perception of taste (GO:0050909)4.15685063
22negative regulation of microtubule polymerization (GO:0031115)4.04396831
23regulation of feeding behavior (GO:0060259)4.01510252
24regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.98667202
25neuronal action potential (GO:0019228)3.85872663
26peripheral nervous system neuron development (GO:0048935)3.84499335
27detection of light stimulus involved in sensory perception (GO:0050962)3.82603997
28detection of light stimulus involved in visual perception (GO:0050908)3.82603997
29peristalsis (GO:0030432)3.79152558
30cellular potassium ion homeostasis (GO:0030007)3.76544592
31synaptic vesicle maturation (GO:0016188)3.76401053
32regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.74770231
33negative regulation of dendrite development (GO:2000171)3.72036007
34regulation of synaptic vesicle transport (GO:1902803)3.71053996
35detection of temperature stimulus (GO:0016048)3.70889997
36negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.69668996
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.69417974
38mitotic cell cycle arrest (GO:0071850)3.67772153
39proline transport (GO:0015824)3.65990037
40sulfur amino acid catabolic process (GO:0000098)3.57460307
41positive regulation of synaptic transmission, GABAergic (GO:0032230)3.56463359
42neurotransmitter secretion (GO:0007269)3.52234953
43energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.52226155
44ATP hydrolysis coupled proton transport (GO:0015991)3.52226155
45membrane depolarization during action potential (GO:0086010)3.50446870
46transepithelial transport (GO:0070633)3.49702774
47regulation of glutamate receptor signaling pathway (GO:1900449)3.48046807
48regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.47979727
49regulation of cytokine production involved in inflammatory response (GO:1900015)3.45971344
50synaptic vesicle docking involved in exocytosis (GO:0016081)3.45028006
51response to gravity (GO:0009629)3.39825871
52adenosine receptor signaling pathway (GO:0001973)3.39574623
53positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.39379352
54neuron-neuron synaptic transmission (GO:0007270)3.38758834
55positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.34910354
56mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.34113281
57innervation (GO:0060384)3.32169484
58peptidyl-glutamic acid carboxylation (GO:0017187)3.31665605
59protein carboxylation (GO:0018214)3.31665605
60cerebellar Purkinje cell differentiation (GO:0021702)3.31299244
61ionotropic glutamate receptor signaling pathway (GO:0035235)3.31258077
62lens fiber cell differentiation (GO:0070306)3.30248321
63GDP-mannose metabolic process (GO:0019673)3.30182914
64DNA strand renaturation (GO:0000733)3.27867586
65calcium-mediated signaling using intracellular calcium source (GO:0035584)3.26102979
66positive regulation of catecholamine secretion (GO:0033605)3.19484975
67transferrin transport (GO:0033572)3.18735990
68neurofilament cytoskeleton organization (GO:0060052)3.16994098
69ATP synthesis coupled proton transport (GO:0015986)3.16647095
70energy coupled proton transport, down electrochemical gradient (GO:0015985)3.16647095
71synaptic transmission, glutamatergic (GO:0035249)3.13371748
72semaphorin-plexin signaling pathway (GO:0071526)3.11891682
73protein retention in ER lumen (GO:0006621)3.09822008
74cerebellar granule cell differentiation (GO:0021707)3.09536204
75glutamate receptor signaling pathway (GO:0007215)3.08794729
76positive regulation of synapse maturation (GO:0090129)3.08413369
77neuromuscular process controlling posture (GO:0050884)3.07353824
78sodium ion export (GO:0071436)3.05788655
79neuron recognition (GO:0008038)3.02991015
80negative regulation of cation channel activity (GO:2001258)3.02948703
81negative regulation of synaptic transmission, GABAergic (GO:0032229)3.02425693
82urinary tract smooth muscle contraction (GO:0014848)3.00053042
83serotonin receptor signaling pathway (GO:0007210)2.99571205
84neurotransmitter transport (GO:0006836)2.99127133
85negative regulation of calcium ion transport into cytosol (GO:0010523)2.99087984
86membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.98135134
87regulation of guanylate cyclase activity (GO:0031282)2.96458043
88calcium ion-dependent exocytosis (GO:0017156)2.95803686
89regulation of synaptic transmission, dopaminergic (GO:0032225)2.95330445
90retinal ganglion cell axon guidance (GO:0031290)2.93753937
91action potential (GO:0001508)2.93418934
92membrane hyperpolarization (GO:0060081)2.93014322
93ferric iron transport (GO:0015682)2.92891235
94trivalent inorganic cation transport (GO:0072512)2.92891235
95G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.92826254
96locomotory exploration behavior (GO:0035641)2.92408611
97striatum development (GO:0021756)2.92209636
98layer formation in cerebral cortex (GO:0021819)2.91845647
99membrane depolarization (GO:0051899)2.88083649
100adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.87487408
101cell communication involved in cardiac conduction (GO:0086065)2.86718851
102regulation of vesicle fusion (GO:0031338)2.86555989
103regulation of neuronal synaptic plasticity (GO:0048168)2.86087869
104nucleotide transmembrane transport (GO:1901679)2.85477767
105synaptic vesicle endocytosis (GO:0048488)2.85416996
106presynaptic membrane assembly (GO:0097105)2.84820177
107acidic amino acid transport (GO:0015800)2.82269234
108dopamine receptor signaling pathway (GO:0007212)2.81774516
109positive regulation of synapse assembly (GO:0051965)2.81729096
110regulation of synaptic transmission, glutamatergic (GO:0051966)2.81490763
111chaperone-mediated protein transport (GO:0072321)2.81355673
112phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.81114149
113neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.80933256
114regulation of postsynaptic membrane potential (GO:0060078)2.80912602
115protein neddylation (GO:0045116)2.80543462
116synapse assembly (GO:0007416)2.80411012
117regulation of excitatory postsynaptic membrane potential (GO:0060079)2.80103399
118exploration behavior (GO:0035640)2.79765668
119cilium or flagellum-dependent cell motility (GO:0001539)2.78289928
120mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.78174481
121postsynaptic membrane organization (GO:0001941)2.78156081
122regulation of neurotransmitter secretion (GO:0046928)2.77350595
123adenine nucleotide transport (GO:0051503)2.76793655
124regulation of synapse structural plasticity (GO:0051823)2.75671903
125gamma-aminobutyric acid signaling pathway (GO:0007214)2.75210682
126establishment of synaptic vesicle localization (GO:0097480)2.74871127
127synaptic vesicle transport (GO:0048489)2.74871127
128establishment of mitochondrion localization (GO:0051654)2.74181174
129regulation of sodium ion transmembrane transporter activity (GO:2000649)2.73959277
130L-glutamate transport (GO:0015813)2.73890989
131positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.73127601
132synaptic transmission (GO:0007268)2.72894986
133regulation of long-term neuronal synaptic plasticity (GO:0048169)2.72209193
134response to histamine (GO:0034776)2.71064637
135presynaptic membrane organization (GO:0097090)2.70977639
136regulation of dopamine secretion (GO:0014059)2.70835172
137dicarboxylic acid transport (GO:0006835)2.70557176
138behavioral response to cocaine (GO:0048148)2.70359273
139organelle transport along microtubule (GO:0072384)2.70075146
140prepulse inhibition (GO:0060134)2.69386094
141positive regulation of guanylate cyclase activity (GO:0031284)2.69324179
142maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.69147396
143establishment of vesicle localization (GO:0051650)2.68817550
144regulation of protein kinase A signaling (GO:0010738)2.68188304
145ovulation cycle (GO:0042698)2.66549058
146regulation of neurotransmitter levels (GO:0001505)2.66526212
147positive regulation of heat generation (GO:0031652)2.65493493
148regulation of catecholamine metabolic process (GO:0042069)2.64967352
149regulation of dopamine metabolic process (GO:0042053)2.64967352
150regulation of action potential (GO:0098900)2.64022712
151long-term memory (GO:0007616)2.63017629
152type B pancreatic cell proliferation (GO:0044342)2.62049607
153sodium ion transmembrane transport (GO:0035725)2.51827091
154myelin assembly (GO:0032288)2.48780570
155mating behavior (GO:0007617)2.48366133
156visual learning (GO:0008542)2.47902262
157positive regulation of vesicle fusion (GO:0031340)2.47638432
158purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.47355001
1593-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.47355001
160adult feeding behavior (GO:0008343)2.47079574
161regulation of ARF protein signal transduction (GO:0032012)2.45116966
162behavioral response to pain (GO:0048266)2.45001466
163peptidyl-tyrosine autophosphorylation (GO:0038083)2.43753443
164regulation of synaptic plasticity (GO:0048167)2.41703524

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.18114124
2GBX2_23144817_ChIP-Seq_PC3_Human3.61696108
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.13621049
4TAF15_26573619_Chip-Seq_HEK293_Human2.96942176
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.95388510
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91057189
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.76898560
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.71352020
9GATA1_22025678_ChIP-Seq_K562_Human2.63792592
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.58766696
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.56881031
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.56881031
13REST_21632747_ChIP-Seq_MESCs_Mouse2.55868643
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55822478
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.51173488
16PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.43240360
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.39809621
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.39232874
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.38824670
20BMI1_23680149_ChIP-Seq_NPCS_Mouse2.38707321
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36952729
22VDR_22108803_ChIP-Seq_LS180_Human2.36784898
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.36643635
24P68_20966046_ChIP-Seq_HELA_Human2.32126174
25EED_16625203_ChIP-ChIP_MESCs_Mouse2.30330789
26CTBP2_25329375_ChIP-Seq_LNCAP_Human2.27052161
27CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.20403007
28SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12301221
29REST_18959480_ChIP-ChIP_MESCs_Mouse2.11777541
30MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human2.09303139
31EZH2_27294783_Chip-Seq_ESCs_Mouse2.08973370
32CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04916937
33LXR_22292898_ChIP-Seq_THP-1_Human2.02499822
34CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.97885214
35RNF2_27304074_Chip-Seq_ESCs_Mouse1.94532601
36VDR_21846776_ChIP-Seq_THP-1_Human1.87754452
37RARG_19884340_ChIP-ChIP_MEFs_Mouse1.87643051
38GATA1_26923725_Chip-Seq_HPCs_Mouse1.81868487
39TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81443192
40AR_21572438_ChIP-Seq_LNCaP_Human1.80065721
41P300_19829295_ChIP-Seq_ESCs_Human1.77884928
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.74644432
43RARB_27405468_Chip-Seq_BRAIN_Mouse1.73640767
44XRN2_22483619_ChIP-Seq_HELA_Human1.73367968
45SMAD4_21799915_ChIP-Seq_A2780_Human1.71824187
46ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.70912573
47CTCF_27219007_Chip-Seq_ERYTHROID_Human1.68508652
48TET1_21451524_ChIP-Seq_MESCs_Mouse1.63918332
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.63466497
50DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.62612310
51E2F1_20622854_ChIP-Seq_HELA_Human1.62464798
52PHF8_20622854_ChIP-Seq_HELA_Human1.59907056
53RNF2_27304074_Chip-Seq_NSC_Mouse1.59599768
54ZNF274_21170338_ChIP-Seq_K562_Hela1.57627439
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56695894
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.55655857
57CBX2_27304074_Chip-Seq_ESCs_Mouse1.54521505
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.51845416
59ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49610573
60ERG_21242973_ChIP-ChIP_JURKAT_Human1.49342278
61SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.48806546
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.46651305
63SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.46379346
64CREB1_26743006_Chip-Seq_LNCaP_Human1.46315362
65EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.45709242
66SMC4_20622854_ChIP-Seq_HELA_Human1.45350786
67SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.44337151
68CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.43639371
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42764073
70DROSHA_22980978_ChIP-Seq_HELA_Human1.40222448
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39495863
72AR_25329375_ChIP-Seq_VCAP_Human1.39204947
73FOXP1_21924763_ChIP-Seq_HESCs_Human1.38707547
74SA1_27219007_Chip-Seq_ERYTHROID_Human1.37784160
75TP53_22127205_ChIP-Seq_IMR90_Human1.35696179
76CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35060374
77RARB_24833708_ChIP-Seq_LIVER_Mouse1.32964753
78CTCF_21964334_Chip-Seq_Bcells_Human1.32442223
79PIAS1_25552417_ChIP-Seq_VCAP_Human1.31608149
80DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.31139850
81IKZF1_21737484_ChIP-ChIP_HCT116_Human1.30557328
82CTCF_20526341_ChIP-Seq_ESCs_Human1.30546855
83SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30504318
84NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.29507220
85RACK7_27058665_Chip-Seq_MCF-7_Human1.29264058
86AHR_22903824_ChIP-Seq_MCF-7_Human1.28960219
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28619328
88ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27066565
89BCL6_27268052_Chip-Seq_Bcells_Human1.25662022
90SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25224078
91SOX2_21211035_ChIP-Seq_LN229_Gbm1.24343917
92RARA_24833708_ChIP-Seq_LIVER_Mouse1.24176873
93BCOR_27268052_Chip-Seq_Bcells_Human1.23980981
94RXRA_24833708_ChIP-Seq_LIVER_Mouse1.22255746
95SMC3_22415368_ChIP-Seq_MEFs_Mouse1.21517045
96SMAD3_21741376_ChIP-Seq_EPCs_Human1.21338555
97SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21079929
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.20438769
99OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.18740027
100MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18608955
101BCAT_22108803_ChIP-Seq_LS180_Human1.17696903
102TP53_23651856_ChIP-Seq_MEFs_Mouse1.14274757
103ZFP281_27345836_Chip-Seq_ESCs_Mouse1.13903086
104UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12701537
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12575459
106POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12482471
107ARNT_22903824_ChIP-Seq_MCF-7_Human1.11980009
108RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.11462649
109ELF1_20517297_ChIP-Seq_JURKAT_Human1.11414048
110RING1B_27294783_Chip-Seq_ESCs_Mouse1.11255434
111PRDM14_20953172_ChIP-Seq_ESCs_Human1.10971987
112KDM2B_26808549_Chip-Seq_K562_Human1.09454160
113CTCF_21964334_ChIP-Seq_BJAB-B_Human1.09076713
114MAF_26560356_Chip-Seq_TH2_Human1.08702583
115ERA_21632823_ChIP-Seq_H3396_Human1.07904055
116RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07518519
117JUN_21703547_ChIP-Seq_K562_Human1.06573386
118TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05658925
119YY1_22570637_ChIP-Seq_MALME-3M_Human1.05333416
120IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05100165
121CBP_20019798_ChIP-Seq_JUKART_Human1.05100165
122ZFP281_18757296_ChIP-ChIP_E14_Mouse1.04207160
123STAT3_23295773_ChIP-Seq_U87_Human1.03059327
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02486589
125RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02245838
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01711018
127TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.01543661
128ESR2_21235772_ChIP-Seq_MCF-7_Human1.00432355
129FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00388829
130EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.00377910
131RUNX2_22187159_ChIP-Seq_PCA_Human1.00310314
132AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.99910398
133FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99848953
134ZNF217_24962896_ChIP-Seq_MCF-7_Human0.99778121
135EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96954142
136SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96655797
137TAF2_19829295_ChIP-Seq_ESCs_Human0.96614448
138MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95647248
139TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95575123
140KDM2B_26808549_Chip-Seq_REH_Human0.94468742
141P53_21459846_ChIP-Seq_SAOS-2_Human0.94150728
142SRY_22984422_ChIP-ChIP_TESTIS_Rat0.93877279
143ER_23166858_ChIP-Seq_MCF-7_Human0.93347738
144DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92540541
145RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.92115671
146FUS_26573619_Chip-Seq_HEK293_Human0.92054132
147SMAD3_21741376_ChIP-Seq_ESCs_Human0.91845785
148YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90969222
149STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90690162
150TP53_20018659_ChIP-ChIP_R1E_Mouse0.90627866
151MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88897294
152KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88669645
153TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.88020883
154CTCF_27219007_Chip-Seq_Bcells_Human0.87719328
155RING1B_27294783_Chip-Seq_NPCs_Mouse0.87177531
156ESR1_20079471_ChIP-ChIP_T-47D_Human0.86392060
157RBPJ_22232070_ChIP-Seq_NCS_Mouse0.86322100
158AR_19668381_ChIP-Seq_PC3_Human0.85798536
159IGF1R_20145208_ChIP-Seq_DFB_Human0.85466819
160TCF4_23295773_ChIP-Seq_U87_Human0.84773525
161TCF4_22108803_ChIP-Seq_LS180_Human0.83229698
162GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83082277

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001968_abnormal_touch/_nociception4.96848036
2MP0002735_abnormal_chemical_nociception4.90158127
3MP0004270_analgesia4.32721666
4MP0002736_abnormal_nociception_after4.30719935
5MP0003880_abnormal_central_pattern4.08890091
6MP0004859_abnormal_synaptic_plasticity4.06030042
7MP0005171_absent_coat_pigmentation3.65563973
8MP0002734_abnormal_mechanical_nocicepti3.46699690
9MP0006276_abnormal_autonomic_nervous3.33778364
10MP0003635_abnormal_synaptic_transmissio3.19008802
11MP0002733_abnormal_thermal_nociception3.13766827
12MP0001986_abnormal_taste_sensitivity2.82774388
13MP0001970_abnormal_pain_threshold2.79082061
14MP0004858_abnormal_nervous_system2.74517502
15MP0009745_abnormal_behavioral_response2.72791764
16MP0005174_abnormal_tail_pigmentation2.68468294
17MP0002063_abnormal_learning/memory/cond2.59160334
18MP0002064_seizures2.58383579
19MP0002272_abnormal_nervous_system2.56748955
20MP0009046_muscle_twitch2.49080231
21MP0002160_abnormal_reproductive_system2.48052901
22MP0002572_abnormal_emotion/affect_behav2.36258030
23MP0002184_abnormal_innervation2.22165190
24MP0002067_abnormal_sensory_capabilities2.17291729
25MP0002638_abnormal_pupillary_reflex2.06129540
26MP0001440_abnormal_grooming_behavior2.00469467
27MP0001501_abnormal_sleep_pattern1.92344315
28MP0001756_abnormal_urination1.91387267
29MP0001661_extended_life_span1.88563869
30MP0006292_abnormal_olfactory_placode1.85150251
31MP0001486_abnormal_startle_reflex1.80357649
32MP0001529_abnormal_vocalization1.76337554
33MP0005423_abnormal_somatic_nervous1.75412709
34MP0003136_yellow_coat_color1.72725997
35MP0002822_catalepsy1.72138169
36MP0000778_abnormal_nervous_system1.69045257
37MP0001984_abnormal_olfaction1.64255003
38MP0004811_abnormal_neuron_physiology1.60135980
39MP0003878_abnormal_ear_physiology1.57956180
40MP0005377_hearing/vestibular/ear_phenot1.57956180
41MP0003941_abnormal_skin_development1.57531406
42MP0003329_amyloid_beta_deposits1.54524945
43MP0005386_behavior/neurological_phenoty1.51250371
44MP0004924_abnormal_behavior1.51250371
45MP0000955_abnormal_spinal_cord1.47231516
46MP0002557_abnormal_social/conspecific_i1.45641064
47MP0003183_abnormal_peptide_metabolism1.44469271
48MP0008875_abnormal_xenobiotic_pharmacok1.42902442
49MP0000751_myopathy1.42568086
50MP0001188_hyperpigmentation1.42506054
51MP0002837_dystrophic_cardiac_calcinosis1.39919582
52MP0003879_abnormal_hair_cell1.39881678
53MP0009379_abnormal_foot_pigmentation1.39030406
54MP0002882_abnormal_neuron_morphology1.35632821
55MP0003122_maternal_imprinting1.35461873
56MP0008004_abnormal_stomach_pH1.34037934
57MP0002751_abnormal_autonomic_nervous1.30591354
58MP0004133_heterotaxia1.30566234
59MP0004142_abnormal_muscle_tone1.28022081
60MP0001905_abnormal_dopamine_level1.24746021
61MP0001664_abnormal_digestion1.24113881
62MP0003705_abnormal_hypodermis_morpholog1.23327464
63MP0002909_abnormal_adrenal_gland1.18804103
64MP0002066_abnormal_motor_capabilities/c1.18525975
65MP0001485_abnormal_pinna_reflex1.16638569
66MP0004885_abnormal_endolymph1.14615439
67MP0004019_abnormal_vitamin_homeostasis1.11826527
68MP0002876_abnormal_thyroid_physiology1.09746640
69MP0009780_abnormal_chondrocyte_physiolo1.08136558
70MP0010386_abnormal_urinary_bladder1.07515225
71MP0008569_lethality_at_weaning1.07246994
72MP0004130_abnormal_muscle_cell1.00168686
73MP0005389_reproductive_system_phenotype0.97391892
74MP0000538_abnormal_urinary_bladder0.97260305
75MP0008260_abnormal_autophagy0.96971030
76MP0008872_abnormal_physiological_respon0.93123048
77MP0002752_abnormal_somatic_nervous0.92161255
78MP0002229_neurodegeneration0.91992561
79MP0000537_abnormal_urethra_morphology0.90906324
80MP0005646_abnormal_pituitary_gland0.86951837
81MP0004085_abnormal_heartbeat0.86476154
82MP0000003_abnormal_adipose_tissue0.85584465
83MP0000383_abnormal_hair_follicle0.85067501
84MP0001346_abnormal_lacrimal_gland0.84338595
85MP0004484_altered_response_of0.83854318
86MP0005501_abnormal_skin_physiology0.83318496
87MP0004742_abnormal_vestibular_system0.82664964
88MP0005410_abnormal_fertilization0.80509461
89MP0008874_decreased_physiological_sensi0.79931000
90MP0001963_abnormal_hearing_physiology0.79461275
91MP0002163_abnormal_gland_morphology0.79449906
92MP0004043_abnormal_pH_regulation0.78914045
93MP0010234_abnormal_vibrissa_follicle0.78611504
94MP0002069_abnormal_eating/drinking_beha0.78231981
95MP0002152_abnormal_brain_morphology0.77617142
96MP0001502_abnormal_circadian_rhythm0.76541308
97MP0004215_abnormal_myocardial_fiber0.74284905
98MP0003453_abnormal_keratinocyte_physiol0.74049404
99MP0005083_abnormal_biliary_tract0.73050007
100MP0005645_abnormal_hypothalamus_physiol0.71067427
101MP0003633_abnormal_nervous_system0.70769760
102MP0005330_cardiomyopathy0.70159197
103MP0005332_abnormal_amino_acid0.69752521
104MP0005551_abnormal_eye_electrophysiolog0.68486105
105MP0005394_taste/olfaction_phenotype0.68456568
106MP0005499_abnormal_olfactory_system0.68456568
107MP0001348_abnormal_lacrimal_gland0.67948994
108MP0003119_abnormal_digestive_system0.67320000
109MP0005535_abnormal_body_temperature0.66829640
110MP0000534_abnormal_ureter_morphology0.65724751
111MP0003631_nervous_system_phenotype0.65715380
112MP0006035_abnormal_mitochondrial_morpho0.65486581
113MP0003634_abnormal_glial_cell0.65380371
114MP0003787_abnormal_imprinting0.61413792
115MP0000358_abnormal_cell_content/0.61343576
116MP0005084_abnormal_gallbladder_morpholo0.61086301
117MP0000747_muscle_weakness0.60770466
118MP0000427_abnormal_hair_cycle0.60651914
119MP0000470_abnormal_stomach_morphology0.59822144
120MP0010678_abnormal_skin_adnexa0.59572963
121MP0000604_amyloidosis0.58686833
122MP0000750_abnormal_muscle_regeneration0.58148188
123MP0010771_integument_phenotype0.55245107
124MP0001943_abnormal_respiration0.55083193
125MP0003137_abnormal_impulse_conducting0.54501070
126MP0002653_abnormal_ependyma_morphology0.54297423
127MP0005409_darkened_coat_color0.53310533
128MP0000026_abnormal_inner_ear0.52341958
129MP0004147_increased_porphyrin_level0.51357632
130MP0001270_distended_abdomen0.50607653
131MP0001765_abnormal_ion_homeostasis0.49593097
132MP0002332_abnormal_exercise_endurance0.48977272
133MP0000631_abnormal_neuroendocrine_gland0.48310653
134MP0000013_abnormal_adipose_tissue0.47128873
135MP0003646_muscle_fatigue0.45514690
136MP0000230_abnormal_systemic_arterial0.44882657
137MP0003315_abnormal_perineum_morphology0.44810837

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.26025468
2Focal motor seizures (HP:0011153)6.17205968
3Testicular atrophy (HP:0000029)6.04798122
4Rib fusion (HP:0000902)5.68466261
5Atonic seizures (HP:0010819)5.18993713
6Focal seizures (HP:0007359)4.83811533
7Febrile seizures (HP:0002373)4.78481414
8Poikiloderma (HP:0001029)4.68314741
9Attenuation of retinal blood vessels (HP:0007843)4.64109207
10Akinesia (HP:0002304)4.58451587
11Rectal fistula (HP:0100590)4.53010250
12Rectovaginal fistula (HP:0000143)4.53010250
13Annular pancreas (HP:0001734)4.37099189
14Vaginal fistula (HP:0004320)4.27037743
15Intestinal fistula (HP:0100819)4.17456162
16Ulnar claw (HP:0001178)4.12132209
17Insidious onset (HP:0003587)4.06785052
18Termporal pattern (HP:0011008)4.06785052
19Pheochromocytoma (HP:0002666)3.98284678
20Dyschromatopsia (HP:0007641)3.97674234
21Absence seizures (HP:0002121)3.96381443
22Mesangial abnormality (HP:0001966)3.91772450
23Epileptic encephalopathy (HP:0200134)3.90750430
24Progressive cerebellar ataxia (HP:0002073)3.83538482
25Ulnar bowing (HP:0003031)3.81572763
26Neuroendocrine neoplasm (HP:0100634)3.80416661
27Popliteal pterygium (HP:0009756)3.77540268
28Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.67465385
29Choroideremia (HP:0001139)3.65187354
30Turricephaly (HP:0000262)3.58063520
31Dialeptic seizures (HP:0011146)3.53804977
32Aplasia of the musculature (HP:0100854)3.50858985
33Visual hallucinations (HP:0002367)3.50161099
34Action tremor (HP:0002345)3.49055940
35Genetic anticipation (HP:0003743)3.48780639
36Coronal craniosynostosis (HP:0004440)3.43457777
37Increased hepatocellular lipid droplets (HP:0006565)3.39816176
38Lipid accumulation in hepatocytes (HP:0006561)3.31523967
39Congenital stationary night blindness (HP:0007642)3.26289519
40Abnormality of pain sensation (HP:0010832)3.24065550
41Impaired pain sensation (HP:0007328)3.24065550
42Abnormality of the intrinsic pathway (HP:0010989)3.22996258
43Acute necrotizing encephalopathy (HP:0006965)3.18224793
44Limb dystonia (HP:0002451)3.10662221
45Decreased number of large peripheral myelinated nerve fibers (HP:0003387)3.10089968
46Short chin (HP:0000331)3.07799502
47Generalized tonic-clonic seizures (HP:0002069)3.07097982
48Chronic hepatic failure (HP:0100626)3.04129015
49Neonatal onset (HP:0003623)3.00238886
50Facial diplegia (HP:0001349)2.98101713
51Bony spicule pigmentary retinopathy (HP:0007737)2.98031678
52Renal Fanconi syndrome (HP:0001994)2.97490557
53Hyperventilation (HP:0002883)2.97141435
54Abnormal hair whorl (HP:0010721)2.94279629
55Amblyopia (HP:0000646)2.92706215
56Decreased central vision (HP:0007663)2.92185754
57Thin bony cortex (HP:0002753)2.91908321
58Abnormal mitochondria in muscle tissue (HP:0008316)2.91174159
59Chorioretinal atrophy (HP:0000533)2.90778023
60Failure to thrive in infancy (HP:0001531)2.89672218
61Ankle clonus (HP:0011448)2.88235307
62Abnormality of the vocal cords (HP:0008777)2.82438771
63Progressive macrocephaly (HP:0004481)2.82199054
64Progressive inability to walk (HP:0002505)2.79115750
65Hypothermia (HP:0002045)2.78158219
66Amniotic constriction ring (HP:0009775)2.68093944
67Abnormality of placental membranes (HP:0011409)2.68093944
68Aplasia/Hypoplasia of the brainstem (HP:0007362)2.62085106
69Hypoplasia of the brainstem (HP:0002365)2.62085106
70Diminished movement (HP:0002374)2.54513093
71Mitochondrial inheritance (HP:0001427)2.53560412
72Choanal stenosis (HP:0000452)2.52837743
73Dysautonomia (HP:0002459)2.52007694
74Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.51608936
75Increased serum pyruvate (HP:0003542)2.48615921
76Abnormality of glycolysis (HP:0004366)2.48615921
77Truncal ataxia (HP:0002078)2.47512339
78Myotonia (HP:0002486)2.45820133
79Polyphagia (HP:0002591)2.45205652
80Urinary urgency (HP:0000012)2.41478823
81Short humerus (HP:0005792)2.41430194
82Anteriorly placed anus (HP:0001545)2.41217239
83Prolonged partial thromboplastin time (HP:0003645)2.40908265
84Acute encephalopathy (HP:0006846)2.39713423
85Abnormal eating behavior (HP:0100738)2.39697865
86Facial hemangioma (HP:0000329)2.39474528
87Hemorrhage of the eye (HP:0011885)2.39297989
88Joint hemorrhage (HP:0005261)2.38857948
89Hypoventilation (HP:0002791)2.36577636
90Supranuclear gaze palsy (HP:0000605)2.35607533
91Urinary bladder sphincter dysfunction (HP:0002839)2.34879536
92Impaired vibration sensation in the lower limbs (HP:0002166)2.30484694
93Decreased electroretinogram (ERG) amplitude (HP:0000654)2.29860392
94Mutism (HP:0002300)2.27417317
95Hypoalbuminemia (HP:0003073)2.26862597
96Abnormal albumin level (HP:0012116)2.26862597
97Neoplasm of the peripheral nervous system (HP:0100007)2.26224189
98Atrioventricular block (HP:0001678)2.24679531
99Abnormality of the corticospinal tract (HP:0002492)2.22944474
100Inability to walk (HP:0002540)2.22664443
101Patellar aplasia (HP:0006443)2.21682825
102Autoamputation (HP:0001218)2.20070380
103Increased CSF lactate (HP:0002490)2.19587834
104Poor suck (HP:0002033)2.19251895
105Abnormal social behavior (HP:0012433)2.16439172
106Impaired social interactions (HP:0000735)2.16439172
107Poor eye contact (HP:0000817)2.16135752
108Postural tremor (HP:0002174)2.15170981
109Aplasia/Hypoplasia involving the musculature (HP:0001460)2.12216402
110Dyskinesia (HP:0100660)2.12208399
111Abnormality of magnesium homeostasis (HP:0004921)2.12099496
112Broad-based gait (HP:0002136)2.11661060
113Bowing of the arm (HP:0006488)2.11571753
114Bowed forearm bones (HP:0003956)2.11571753
115Aplasia/hypoplasia of the humerus (HP:0006507)2.11099496
116Oligomenorrhea (HP:0000876)2.09653901
117Vertebral arch anomaly (HP:0008438)2.08863875
118Long clavicles (HP:0000890)2.07043789
119Hypomagnesemia (HP:0002917)2.06716776
120Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.06266598
121Hepatocellular necrosis (HP:0001404)2.06216127
122Fused cervical vertebrae (HP:0002949)2.05155491
123Esotropia (HP:0000565)2.05115601
124Hyperthyroidism (HP:0000836)2.00596097
125Exotropia (HP:0000577)2.00567854
126Aplasia/Hypoplasia of the patella (HP:0006498)2.00288212
127Steppage gait (HP:0003376)2.00240864
128Specific learning disability (HP:0001328)1.98967880
129Abnormal urine phosphate concentration (HP:0012599)1.98917505
130Gaze-evoked nystagmus (HP:0000640)1.97860651
131Torticollis (HP:0000473)1.97221783
132Status epilepticus (HP:0002133)1.96903533
133Gait imbalance (HP:0002141)1.95619593
134Spastic gait (HP:0002064)1.95375091
135Anxiety (HP:0000739)1.95126445
136Squamous cell carcinoma (HP:0002860)1.94365971
137Abnormality of renal resorption (HP:0011038)1.91779467
138Abnormal autonomic nervous system physiology (HP:0012332)1.91552419
139Genital tract atresia (HP:0001827)1.90479139
140Bradycardia (HP:0001662)1.89854604
141Focal dystonia (HP:0004373)1.89596304
142Neonatal respiratory distress (HP:0002643)1.89314391
143Enlarged epiphyses (HP:0010580)1.88318117
144Optic disc pallor (HP:0000543)1.88143075
145Craniofacial dystonia (HP:0012179)1.88015655
146Mask-like facies (HP:0000298)1.87673268
147Depression (HP:0000716)1.86788632
148Rapidly progressive (HP:0003678)1.86083163
149Pendular nystagmus (HP:0012043)1.85606626
150Increased number of teeth (HP:0011069)1.83665198
151Ventricular fibrillation (HP:0001663)1.83079474
152Epileptiform EEG discharges (HP:0011182)1.81870303
153Cerebral hypomyelination (HP:0006808)1.81831494
154Bradykinesia (HP:0002067)1.81385695
155Vaginal atresia (HP:0000148)1.81058172
156Increased muscle lipid content (HP:0009058)1.80830936
157Narrow nasal bridge (HP:0000446)1.80589649
158Exertional dyspnea (HP:0002875)1.80271876
159Dysdiadochokinesis (HP:0002075)1.79814167
160Psychosis (HP:0000709)1.79723380
161Foot dorsiflexor weakness (HP:0009027)1.79582877
162Delusions (HP:0000746)1.79189043
163Increased intramyocellular lipid droplets (HP:0012240)1.79117877
164Abnormal gallbladder physiology (HP:0012438)1.78685677
165Cholecystitis (HP:0001082)1.78685677
166Lower limb muscle weakness (HP:0007340)1.78576514
167Emotional lability (HP:0000712)1.78520492
168X-linked dominant inheritance (HP:0001423)1.77712972
169EEG with generalized epileptiform discharges (HP:0011198)1.75635164
170Spastic tetraplegia (HP:0002510)1.74233813
171Fetal akinesia sequence (HP:0001989)1.73582629
172Hammertoe (HP:0001765)1.72530798
173Resting tremor (HP:0002322)1.72380938
174Abnormality of the costochondral junction (HP:0000919)1.71897606
175Delayed epiphyseal ossification (HP:0002663)1.69626195
176Cystic hygroma (HP:0000476)1.69208689
177Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.68502869
178Malignant hyperthermia (HP:0002047)1.67023868
179Heart block (HP:0012722)1.66134239
180Renal tubular dysfunction (HP:0000124)1.66096272
181Hypophosphatemic rickets (HP:0004912)1.65921839
182Pterygium (HP:0001059)1.63081820
183Zonular cataract (HP:0010920)1.63067269
184Epiphyseal stippling (HP:0010655)1.62014534
185Scanning speech (HP:0002168)1.61193446
186Impaired smooth pursuit (HP:0007772)1.59107616
187Basal cell carcinoma (HP:0002671)1.58445207
188Capillary hemangiomas (HP:0005306)1.57508067

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.02736668
2CASK3.84140819
3MAP3K123.75788892
4NTRK33.53436323
5MAP3K93.31498047
6MINK12.84874290
7GRK52.62838052
8NTRK12.55576549
9MAP3K42.54057103
10MAP2K72.52934397
11MARK12.46042089
12EPHA22.32646331
13KSR22.28663628
14ARAF2.23484713
15RIPK42.17677396
16EPHA41.97594956
17SIK31.95688087
18DAPK21.95353971
19MAP2K41.94777760
20MAP3K21.87767990
21LIMK11.77637260
22MAPK131.69924374
23MUSK1.68172362
24DAPK11.67459658
25NTRK21.64683753
26NME11.61617908
27LMTK21.45242341
28MAPKAPK31.42387101
29KSR11.33518092
30LATS21.28601040
31BCR1.27085653
32PLK21.24089700
33CDK51.20550285
34WNK11.19666474
35BUB11.16042349
36PNCK1.12936602
37MST41.10259765
38MAP4K21.07687506
39RET1.07347500
40TESK21.06017079
41PAK61.05717896
42FER1.02593429
43PDK31.01085950
44PDK41.01085950
45BMPR1B1.00767746
46MATK1.00028262
47UHMK11.00004432
48STK380.99550566
49MAP2K10.98968768
50PTK2B0.98806371
51CDK190.97798519
52PHKG20.96772799
53PHKG10.96772799
54TRIM280.96413605
55AKT30.96141995
56SGK4940.93825508
57SGK2230.93825508
58PRKCG0.93447871
59SIK20.93293851
60CDK140.92645315
61CAMK2A0.86950519
62DDR20.86142363
63TNIK0.85031738
64BRD40.83221151
65CDK180.82959055
66PRKD20.82783646
67CAMKK20.82696213
68PRKCE0.82052942
69ERBB40.82052754
70DYRK1B0.81007085
71CAMK2B0.80451349
72PRKD30.78934023
73WNK30.75848842
74BRAF0.75575792
75MARK20.75150738
76PAK10.74670247
77TSSK60.74445617
78SGK20.73979250
79OXSR10.71252575
80ADRBK10.71126379
81MYLK0.70951906
82CDK150.70568266
83CAMK2D0.70556886
84NEK10.70437684
85RPS6KA20.67968009
86STK110.67967982
87PDPK10.67740292
88PINK10.67321555
89MAP3K10.67024856
90LATS10.66183597
91PTK20.65439303
92MET0.64229568
93CDK11A0.61886108
94CDK60.61551327
95RIPK10.59631673
96AURKA0.59242293
97DYRK20.55385662
98IRAK20.55231130
99GRK70.54210794
100ACVR1B0.53643402
101FES0.53000108
102CAMKK10.52663981
103MAPK100.52270450
104PAK30.50475507
105CAMK2G0.50425420
106SGK10.50117486
107NEK60.49739451
108WNK40.49451960
109BRSK10.49123266
110CAMK1D0.49069672
111PRPF4B0.47981081
112CSNK1G20.47928138
113CAMK40.47225035
114STK390.46282559
115PBK0.45813942
116PRKCI0.45502271
117CCNB10.45433588
118ERBB30.44107207
119PLK10.43753632
120FRK0.43441579
121PRKAA10.43392206
122DAPK30.43133014
123PRKCZ0.42909851
124CAMK1G0.42419922
125PAK40.40811089
126PRKACA0.40680079
127MAPK80.40576873
128PRKCH0.40502786
129TESK10.40075720
130ROCK20.39747938
131TYRO30.38050912
132PDK20.37814171
133CDK80.37457199
134DYRK1A0.36971021
135RAF10.35832712
136MAPKAPK50.35434892
137ADRBK20.34732870
138MST1R0.34032132
139TNK20.32685019
140MAP3K130.32264368
141CAMK10.32202884

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006044.11663515
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.88980093
3Synaptic vesicle cycle_Homo sapiens_hsa047213.88447167
4Nicotine addiction_Homo sapiens_hsa050333.22821541
5Sulfur relay system_Homo sapiens_hsa041223.18375626
6Collecting duct acid secretion_Homo sapiens_hsa049663.10242788
7Oxidative phosphorylation_Homo sapiens_hsa001902.96965045
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.92895195
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.47090603
10Parkinsons disease_Homo sapiens_hsa050122.38192598
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.21239944
12Taste transduction_Homo sapiens_hsa047422.13357122
13Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.12069879
14Olfactory transduction_Homo sapiens_hsa047402.07142616
15GABAergic synapse_Homo sapiens_hsa047272.01123013
16Alzheimers disease_Homo sapiens_hsa050101.97796305
17Long-term potentiation_Homo sapiens_hsa047201.97101367
18Cardiac muscle contraction_Homo sapiens_hsa042601.93529898
19Vibrio cholerae infection_Homo sapiens_hsa051101.90155497
20Dopaminergic synapse_Homo sapiens_hsa047281.88154219
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.86618641
22Circadian entrainment_Homo sapiens_hsa047131.84017630
23Glutamatergic synapse_Homo sapiens_hsa047241.80478638
24Amphetamine addiction_Homo sapiens_hsa050311.73762134
25Insulin secretion_Homo sapiens_hsa049111.69901351
26Salivary secretion_Homo sapiens_hsa049701.69444310
27Morphine addiction_Homo sapiens_hsa050321.69316862
28Serotonergic synapse_Homo sapiens_hsa047261.67598300
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60918235
30Huntingtons disease_Homo sapiens_hsa050161.55463511
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.48892972
32Gastric acid secretion_Homo sapiens_hsa049711.43465922
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36274841
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.34601505
35Cholinergic synapse_Homo sapiens_hsa047251.34548585
36Long-term depression_Homo sapiens_hsa047301.34404132
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.34274625
38Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.34041375
39Renin secretion_Homo sapiens_hsa049241.30106248
40Sphingolipid metabolism_Homo sapiens_hsa006001.29891714
41Calcium signaling pathway_Homo sapiens_hsa040201.22561328
42Circadian rhythm_Homo sapiens_hsa047101.20295321
43Gap junction_Homo sapiens_hsa045401.18624684
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.17395175
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.16259202
46Hippo signaling pathway_Homo sapiens_hsa043901.16231687
47Hedgehog signaling pathway_Homo sapiens_hsa043401.14291981
48Cocaine addiction_Homo sapiens_hsa050301.13849685
49GnRH signaling pathway_Homo sapiens_hsa049121.13834203
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11317527
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.09972146
52Oxytocin signaling pathway_Homo sapiens_hsa049211.08615233
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.07849479
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04045722
55Aldosterone synthesis and secretion_Homo sapiens_hsa049251.02977743
56Axon guidance_Homo sapiens_hsa043601.01326341
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97828175
58Glycosaminoglycan degradation_Homo sapiens_hsa005310.90170766
59Phototransduction_Homo sapiens_hsa047440.88054291
60Basal cell carcinoma_Homo sapiens_hsa052170.83880576
61Mineral absorption_Homo sapiens_hsa049780.82784342
62Pyruvate metabolism_Homo sapiens_hsa006200.81855921
63Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81542744
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79573966
65Inositol phosphate metabolism_Homo sapiens_hsa005620.79154682
66ErbB signaling pathway_Homo sapiens_hsa040120.78826401
67Melanogenesis_Homo sapiens_hsa049160.77247082
68Regulation of autophagy_Homo sapiens_hsa041400.72820957
69Phagosome_Homo sapiens_hsa041450.72764880
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72260352
71Vitamin B6 metabolism_Homo sapiens_hsa007500.69439306
722-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69438773
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.69211482
74Estrogen signaling pathway_Homo sapiens_hsa049150.66865999
75Dorso-ventral axis formation_Homo sapiens_hsa043200.66678229
76Pancreatic secretion_Homo sapiens_hsa049720.66510024
77Glioma_Homo sapiens_hsa052140.66042136
78Thyroid hormone synthesis_Homo sapiens_hsa049180.65195474
79Fructose and mannose metabolism_Homo sapiens_hsa000510.64710871
80cAMP signaling pathway_Homo sapiens_hsa040240.64002172
81Arginine biosynthesis_Homo sapiens_hsa002200.62949705
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.62090865
83Rheumatoid arthritis_Homo sapiens_hsa053230.61808112
84Wnt signaling pathway_Homo sapiens_hsa043100.61772754
85Oocyte meiosis_Homo sapiens_hsa041140.60352387
86Nitrogen metabolism_Homo sapiens_hsa009100.59785577
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58893833
88Thyroid cancer_Homo sapiens_hsa052160.57789547
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57520344
90Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56346759
91Proteasome_Homo sapiens_hsa030500.56338644
92Vitamin digestion and absorption_Homo sapiens_hsa049770.55977018
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55217525
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52293805
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50560263
96Type II diabetes mellitus_Homo sapiens_hsa049300.48540038
97Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47976497
98Cyanoamino acid metabolism_Homo sapiens_hsa004600.47698242
99Bile secretion_Homo sapiens_hsa049760.44854740
100Insulin signaling pathway_Homo sapiens_hsa049100.43164637
101VEGF signaling pathway_Homo sapiens_hsa043700.43104926
102Choline metabolism in cancer_Homo sapiens_hsa052310.41712191
103MAPK signaling pathway_Homo sapiens_hsa040100.41349531
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41207190
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.41110743
106Melanoma_Homo sapiens_hsa052180.40476333
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40309601
108Renin-angiotensin system_Homo sapiens_hsa046140.39930475
109Chemical carcinogenesis_Homo sapiens_hsa052040.39284174
110Endocytosis_Homo sapiens_hsa041440.37900222
111Arginine and proline metabolism_Homo sapiens_hsa003300.37399658
112Ras signaling pathway_Homo sapiens_hsa040140.36969473
113Tight junction_Homo sapiens_hsa045300.36778931
114Endometrial cancer_Homo sapiens_hsa052130.35972505
115Butanoate metabolism_Homo sapiens_hsa006500.35726566
116Ovarian steroidogenesis_Homo sapiens_hsa049130.35721271
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.34963075
118Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34830956
119Lysine degradation_Homo sapiens_hsa003100.33376652
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32999170
121Rap1 signaling pathway_Homo sapiens_hsa040150.32344910
122TGF-beta signaling pathway_Homo sapiens_hsa043500.31405955
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31296493
124Selenocompound metabolism_Homo sapiens_hsa004500.30367370
125Glutathione metabolism_Homo sapiens_hsa004800.30168546
126Glucagon signaling pathway_Homo sapiens_hsa049220.30018300
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.28621613
128Steroid hormone biosynthesis_Homo sapiens_hsa001400.28306259
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.28260354
130Dilated cardiomyopathy_Homo sapiens_hsa054140.28052593
131Alcoholism_Homo sapiens_hsa050340.27794408
132Fatty acid elongation_Homo sapiens_hsa000620.27223680
133Histidine metabolism_Homo sapiens_hsa003400.26901003
134Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.23384935

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