VSTM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.83046654
2negative regulation of cell killing (GO:0031342)5.70016471
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.70016471
4neutrophil activation involved in immune response (GO:0002283)5.68065158
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.44690034
6positive regulation by organism of defense response of other organism involved in symbiotic interact5.44690034
7modulation by symbiont of host immune response (GO:0052553)5.44690034
8positive regulation by symbiont of host defense response (GO:0052509)5.44690034
9modulation by symbiont of host defense response (GO:0052031)5.44690034
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.44690034
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.27381787
12leukocyte aggregation (GO:0070486)5.06905718
13detection of other organism (GO:0098543)4.98321816
14leukocyte migration involved in inflammatory response (GO:0002523)4.96430886
15response to peptidoglycan (GO:0032494)4.91243303
16detection of bacterium (GO:0016045)4.81315237
17cellular extravasation (GO:0045123)4.76122989
18regulation of B cell receptor signaling pathway (GO:0050855)4.74646618
19macrophage activation involved in immune response (GO:0002281)4.65819182
20neutrophil activation (GO:0042119)4.65496948
21antigen processing and presentation of endogenous antigen (GO:0019883)4.44059139
22activated T cell proliferation (GO:0050798)4.43414010
23regulation of gamma-delta T cell activation (GO:0046643)4.39420955
24microglial cell activation (GO:0001774)4.29280348
25antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.28432280
26respiratory burst (GO:0045730)4.20794381
27detection of external biotic stimulus (GO:0098581)4.10020948
28defense response to fungus (GO:0050832)4.07124462
29negative regulation of lymphocyte mediated immunity (GO:0002707)4.06187385
30regulation of mast cell degranulation (GO:0043304)4.06121127
31granulocyte activation (GO:0036230)4.05209262
32regulation of gamma-delta T cell differentiation (GO:0045586)4.02842618
33myeloid cell activation involved in immune response (GO:0002275)3.99327542
34positive regulation of mast cell activation (GO:0033005)3.98665081
35negative regulation of interleukin-12 production (GO:0032695)3.96649415
36response to host immune response (GO:0052572)3.96520264
37response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.96520264
38neutrophil mediated immunity (GO:0002446)3.93518460
39immunoglobulin mediated immune response (GO:0016064)3.90867313
40positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.90522134
41negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.89381461
42regulation of mast cell activation involved in immune response (GO:0033006)3.89223979
43regulation of mast cell activation (GO:0033003)3.86387684
44negative regulation of phagocytosis (GO:0050765)3.79402446
45leukocyte degranulation (GO:0043299)3.78838992
46antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.76425134
47detection of molecule of bacterial origin (GO:0032490)3.72226715
48detection of biotic stimulus (GO:0009595)3.71292776
49production of molecular mediator involved in inflammatory response (GO:0002532)3.68542462
50response to interleukin-15 (GO:0070672)3.67838957
51mast cell activation (GO:0045576)3.66736027
52cellular response to interleukin-15 (GO:0071350)3.66476465
53regulation of myeloid leukocyte mediated immunity (GO:0002886)3.64548302
54response to fungus (GO:0009620)3.56861294
55macrophage activation (GO:0042116)3.56001174
56response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.53315369
57response to host (GO:0075136)3.53315369
58response to host defenses (GO:0052200)3.53315369
59positive regulation of mast cell activation involved in immune response (GO:0033008)3.52336741
60positive regulation of mast cell degranulation (GO:0043306)3.52336741
61positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.48940714
62negative regulation of leukocyte mediated immunity (GO:0002704)3.44421370
63regulation of interferon-beta biosynthetic process (GO:0045357)3.42105789
64negative regulation of T cell mediated immunity (GO:0002710)3.41893594
65negative regulation of T-helper cell differentiation (GO:0045623)3.37973793
66negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.37973793
67negative regulation of interleukin-6 production (GO:0032715)3.35338103
68myeloid leukocyte mediated immunity (GO:0002444)3.32195682
69positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.29966927
70regulation of leukocyte degranulation (GO:0043300)3.28631234
71cell wall macromolecule catabolic process (GO:0016998)3.23741988
72positive regulation of B cell differentiation (GO:0045579)3.23012775
73regulation of B cell differentiation (GO:0045577)3.17828499
74negative regulation of interleukin-1 production (GO:0032692)3.15953697
75regulation of interleukin-8 biosynthetic process (GO:0045414)3.14341510
76defense response to protozoan (GO:0042832)3.14190572
77tolerance induction (GO:0002507)3.11740392
78B cell receptor signaling pathway (GO:0050853)3.10514210
79positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.09847144
80mast cell activation involved in immune response (GO:0002279)3.06757494
81mast cell degranulation (GO:0043303)3.06757494
82killing of cells of other organism (GO:0031640)3.05063711
83disruption of cells of other organism (GO:0044364)3.05063711
84regulation of tolerance induction (GO:0002643)3.02793186
85B cell mediated immunity (GO:0019724)3.01583206
86response to muramyl dipeptide (GO:0032495)2.99045403
87regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.98589635
88positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.98295938
89superoxide anion generation (GO:0042554)2.97310426
90regulation of regulated secretory pathway (GO:1903305)2.96396878
91negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.94570095
92negative regulation of interleukin-1 beta production (GO:0032691)2.92663609
93positive regulation of granulocyte differentiation (GO:0030854)2.90845595
94myeloid leukocyte activation (GO:0002274)2.90601244
95regulation of interleukin-6 biosynthetic process (GO:0045408)2.90157335
96interferon-gamma production (GO:0032609)2.89885278
97regulation of T cell tolerance induction (GO:0002664)2.89867870
98antigen processing and presentation via MHC class Ib (GO:0002475)2.89588990
99neutrophil chemotaxis (GO:0030593)2.89069937
100response to protozoan (GO:0001562)2.83148991

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.54249578
2BP1_19119308_ChIP-ChIP_Hs578T_Human4.98637565
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.98706241
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.73817951
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.67212953
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.16742121
7SPI1_23547873_ChIP-Seq_NB4_Human3.08157509
8IRF8_27001747_Chip-Seq_BMDM_Mouse3.03919165
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.99397449
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.96694996
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.90129259
12RUNX_20019798_ChIP-Seq_JUKART_Human2.84141841
13RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.76756727
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.61169040
15MYB_21317192_ChIP-Seq_ERMYB_Mouse2.59022177
16VDR_24763502_ChIP-Seq_THP-1_Human2.54847046
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.48486293
18IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.48259556
19MYB_26560356_Chip-Seq_TH2_Human2.47575941
20SPI1_23127762_ChIP-Seq_K562_Human2.42350921
21VDR_21846776_ChIP-Seq_THP-1_Human2.41723618
22SCL_19346495_ChIP-Seq_HPC-7_Human2.41092163
23LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.39433537
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.26672688
25STAT4_19710469_ChIP-ChIP_TH1__Mouse2.16106231
26MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.15880983
27RUNX1_22412390_ChIP-Seq_EML_Mouse2.05238694
28LMO2_20887958_ChIP-Seq_HPC-7_Mouse2.04193973
29UTX_26944678_Chip-Seq_JUKART_Human2.03020223
30MAF_26560356_Chip-Seq_TH1_Human2.02254824
31MYB_26560356_Chip-Seq_TH1_Human2.00240802
32FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.96074922
33* VDR_24787735_ChIP-Seq_THP-1_Human1.93674409
34GATA3_27048872_Chip-Seq_THYMUS_Human1.91851886
35E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.87045761
36GATA3_26560356_Chip-Seq_TH2_Human1.84138727
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.79834199
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.68325815
39STAT6_21828071_ChIP-Seq_BEAS2B_Human1.64999083
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62191199
41ELF1_17652178_ChIP-ChIP_JURKAT_Human1.60007248
42GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.58019615
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.54782115
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.52482188
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.51552612
46Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.50169055
47CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.49981740
48MAF_26560356_Chip-Seq_TH2_Human1.48024513
49PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.44252862
50PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43691010
51GATA1_19941827_ChIP-Seq_MEL_Mouse1.40715964
52CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.38827834
53VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.35713896
54RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.32030081
55* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29389479
56BCL6_27268052_Chip-Seq_Bcells_Human1.28762220
57GATA2_22383799_ChIP-Seq_G1ME_Mouse1.26612040
58SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20495393
59PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20403681
60RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.20234989
61TCF7_22412390_ChIP-Seq_EML_Mouse1.19347064
62CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19344649
63CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.18873003
64MYC_22102868_ChIP-Seq_BL_Human1.15219943
65GATA1_22025678_ChIP-Seq_K562_Human1.13323233
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10863814
67SPI1_20517297_ChIP-Seq_HL60_Human1.10619917
68RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09899227
69GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09761893
70NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.08972591
71SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08899567
72CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08083326
73GATA1_19941826_ChIP-Seq_K562_Human1.06886065
74* SMRT_27268052_Chip-Seq_Bcells_Human1.06313803
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.05361026
76ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.05201846
77PU_27001747_Chip-Seq_BMDM_Mouse1.05081875
78GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04425614
79CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.01753661
80EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99651124
81TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.99496318
82KDM2B_26808549_Chip-Seq_SUP-B15_Human0.98776256
83KDM2B_26808549_Chip-Seq_DND41_Human0.98522146
84PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96451459
85GATA2_19941826_ChIP-Seq_K562_Human0.96331742
86FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95924162
87KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95885916
88PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95488610
89BCOR_27268052_Chip-Seq_Bcells_Human0.95089858
90RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94350609
91EGR1_19032775_ChIP-ChIP_M12_Human0.92774023
92GATA2_21666600_ChIP-Seq_HMVEC_Human0.91803453
93KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.91422216
94P300_27268052_Chip-Seq_Bcells_Human0.90552025
95ELF1_20517297_ChIP-Seq_JURKAT_Human0.87459454
96GATA3_26560356_Chip-Seq_TH1_Human0.86713724
97KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.86295383
98NANOG_20526341_ChIP-Seq_ESCs_Human0.86052505
99RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85574170
100ETV2_25802403_ChIP-Seq_MESCs_Mouse0.84838383

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003724_increased_susceptibility_to4.67699812
2MP0003436_decreased_susceptibility_to4.05819208
3MP0006082_CNS_inflammation3.82153085
4MP0001835_abnormal_antigen_presentation3.57710247
5MP0002419_abnormal_innate_immunity3.25111700
6MP0005671_abnormal_response_to3.12868888
7MP0009785_altered_susceptibility_to3.10342806
8MP0001800_abnormal_humoral_immune2.96545999
9MP0005025_abnormal_response_to2.92338817
10MP0002132_abnormal_respiratory_system2.87742515
11MP0003303_peritoneal_inflammation2.87116459
12MP0005000_abnormal_immune_tolerance2.74221493
13MP0002723_abnormal_immune_serum2.61289390
14MP0002420_abnormal_adaptive_immunity2.56155676
15MP0001819_abnormal_immune_cell2.53591408
16MP0002452_abnormal_antigen_presenting2.52180406
17MP0005387_immune_system_phenotype2.49234842
18MP0001790_abnormal_immune_system2.49234842
19MP0000685_abnormal_immune_system2.41372906
20MP0002148_abnormal_hypersensitivity_rea2.29636770
21MP0002405_respiratory_system_inflammati2.21464800
22MP0005464_abnormal_platelet_physiology2.06764676
23MP0001533_abnormal_skeleton_physiology2.06505890
24MP0003763_abnormal_thymus_physiology1.99983127
25MP0002398_abnormal_bone_marrow1.96830759
26MP0003172_abnormal_lysosome_physiology1.95936730
27MP0000716_abnormal_immune_system1.91720427
28MP0003828_pulmonary_edema1.89137582
29MP0001845_abnormal_inflammatory_respons1.82979559
30MP0001545_abnormal_hematopoietic_system1.78284392
31MP0005397_hematopoietic_system_phenotyp1.78284392
32MP0009764_decreased_sensitivity_to1.73762061
33MP0009278_abnormal_bone_marrow1.71858307
34MP0000689_abnormal_spleen_morphology1.67956058
35MP0010155_abnormal_intestine_physiology1.65124735
36MP0002722_abnormal_immune_system1.64986641
37MP0003300_gastrointestinal_ulcer1.64103847
38MP0000465_gastrointestinal_hemorrhage1.62097840
39MP0004510_myositis1.60797909
40MP0001873_stomach_inflammation1.59947014
41MP0008469_abnormal_protein_level1.55931777
42MP0002429_abnormal_blood_cell1.52009381
43MP0005075_abnormal_melanosome_morpholog1.51477073
44MP0003191_abnormal_cellular_cholesterol1.47893612
45MP0000703_abnormal_thymus_morphology1.40265399
46MP0003866_abnormal_defecation1.37784720
47MP0001986_abnormal_taste_sensitivity1.35402762
48MP0009333_abnormal_splenocyte_physiolog1.32724018
49MP0003183_abnormal_peptide_metabolism1.32576565
50MP0008260_abnormal_autophagy1.31246525
51MP0001851_eye_inflammation1.30383848
52MP0004883_abnormal_blood_vessel1.29652727
53MP0004947_skin_inflammation1.29343466
54MP0005083_abnormal_biliary_tract1.28460634
55MP0002277_abnormal_respiratory_mucosa1.26828276
56MP0003656_abnormal_erythrocyte_physiolo1.21076273
57MP0002396_abnormal_hematopoietic_system1.18631063
58MP0005310_abnormal_salivary_gland1.10436071
59MP0005084_abnormal_gallbladder_morpholo1.10161487
60MP0001663_abnormal_digestive_system1.07599148
61MP0000858_altered_metastatic_potential1.06059701
62MP0000015_abnormal_ear_pigmentation1.05807842
63MP0005164_abnormal_response_to0.98636583
64MP0002166_altered_tumor_susceptibility0.98389128
65MP0003806_abnormal_nucleotide_metabolis0.97854343
66MP0002933_joint_inflammation0.96539103
67MP0002928_abnormal_bile_duct0.95691696
68MP0009765_abnormal_xenobiotic_induced0.93469537
69MP0004381_abnormal_hair_follicle0.91245973
70MP0002998_abnormal_bone_remodeling0.90189453
71MP0009763_increased_sensitivity_to0.86798593
72MP0005174_abnormal_tail_pigmentation0.85368828
73MP0003075_altered_response_to0.85149436
74MP0001853_heart_inflammation0.82104244
75MP0005451_abnormal_body_composition0.81155637
76MP0005390_skeleton_phenotype0.78917568
77MP0003252_abnormal_bile_duct0.77327246
78MP0005319_abnormal_enzyme/_coenzyme0.76993896
79MP0002138_abnormal_hepatobiliary_system0.74723645
80MP0002653_abnormal_ependyma_morphology0.70594756
81MP0008004_abnormal_stomach_pH0.69892729
82MP0005166_decreased_susceptibility_to0.69595700
83MP0000343_altered_response_to0.69556349
84MP0003690_abnormal_glial_cell0.69477786
85MP0004808_abnormal_hematopoietic_stem0.64503532
86MP0002006_tumorigenesis0.60850578
87MP0005377_hearing/vestibular/ear_phenot0.60025789
88MP0003878_abnormal_ear_physiology0.60025789
89MP0000490_abnormal_crypts_of0.58137654
90MP0004130_abnormal_muscle_cell0.57725419
91MP0000569_abnormal_digit_pigmentation0.56707684
92MP0003795_abnormal_bone_structure0.55583768
93MP0003787_abnormal_imprinting0.54494712
94MP0003195_calcinosis0.54241287
95MP0000249_abnormal_blood_vessel0.53209187
96MP0005381_digestive/alimentary_phenotyp0.51970707
97MP0004484_altered_response_of0.51095823
98MP0003879_abnormal_hair_cell0.49818859
99MP0005388_respiratory_system_phenotype0.49429911
100MP0002133_abnormal_respiratory_system0.49429911

Predicted human phenotypes

RankGene SetZ-score
1Myositis (HP:0100614)5.92515268
2Stomatitis (HP:0010280)5.92352480
3Eczematoid dermatitis (HP:0000976)5.65562427
4Recurrent abscess formation (HP:0002722)5.56585137
5Elevated erythrocyte sedimentation rate (HP:0003565)5.51585149
6Recurrent bacterial skin infections (HP:0005406)5.51116292
7Abnormality of macrophages (HP:0004311)5.06665683
8Orchitis (HP:0100796)4.90500134
9Optic neuritis (HP:0100653)4.80477054
10Retrobulbar optic neuritis (HP:0100654)4.80477054
11Recurrent gram-negative bacterial infections (HP:0005420)4.65139963
12Hypochromic microcytic anemia (HP:0004840)4.44362385
13Recurrent fungal infections (HP:0002841)4.36704544
14Obstructive lung disease (HP:0006536)4.24722907
15Chronic obstructive pulmonary disease (HP:0006510)4.24722907
16Abnormal delayed hypersensitivity skin test (HP:0002963)3.99876739
17Prolonged bleeding time (HP:0003010)3.88429076
18Recurrent cutaneous fungal infections (HP:0011370)3.84195185
19Chronic mucocutaneous candidiasis (HP:0002728)3.84195185
20Recurrent skin infections (HP:0001581)3.84152391
21Meningitis (HP:0001287)3.64486850
22Mediastinal lymphadenopathy (HP:0100721)3.63377755
23Encephalitis (HP:0002383)3.58340103
24Hypochromic anemia (HP:0001931)3.53989791
25Gastrointestinal infarctions (HP:0005244)3.53492608
26Urticaria (HP:0001025)3.38058197
27Abnormality of the heme biosynthetic pathway (HP:0010472)3.36469274
28Keratoconjunctivitis sicca (HP:0001097)3.35075805
29Vasculitis (HP:0002633)3.25838484
30Keratoconjunctivitis (HP:0001096)3.25780919
31Petechiae (HP:0000967)3.25325657
32Episodic fever (HP:0001954)3.08525419
33Leukocytosis (HP:0001974)3.04880086
34Abnormality of T cells (HP:0002843)3.03578878
35Chest pain (HP:0100749)3.01739028
36Hemoptysis (HP:0002105)3.01482737
37Absent rod-and cone-mediated responses on ERG (HP:0007688)3.00523350
38Constricted visual fields (HP:0001133)2.99951713
39Abnormality of T cell physiology (HP:0011840)2.99270759
40Gingivitis (HP:0000230)2.89463506
41Pulmonary infiltrates (HP:0002113)2.86022839
42Gingival bleeding (HP:0000225)2.84377811
43Epistaxis (HP:0000421)2.79332225
44Abnormality of T cell number (HP:0011839)2.74351364
45T lymphocytopenia (HP:0005403)2.68845091
46Granulocytopenia (HP:0001913)2.66264068
47Spontaneous hematomas (HP:0007420)2.66199101
48Pustule (HP:0200039)2.65425818
49Increased IgE level (HP:0003212)2.64885587
50Increased IgM level (HP:0003496)2.64674166
51Arterial thrombosis (HP:0004420)2.61683003
52Microcytic anemia (HP:0001935)2.59921852
53Panhypogammaglobulinemia (HP:0003139)2.59862676
54Toxemia of pregnancy (HP:0100603)2.57270622
55Anorexia (HP:0002039)2.57268443
56Inflammation of the large intestine (HP:0002037)2.44744032
57Eosinophilia (HP:0001880)2.43025604
58Recurrent viral infections (HP:0004429)2.41983527
59Metaphyseal cupping (HP:0003021)2.40314827
60Abnormal rod and cone electroretinograms (HP:0008323)2.39156275
61Amyloidosis (HP:0011034)2.37429192
62Pulmonary embolism (HP:0002204)2.34062586
63Abnormality of eosinophils (HP:0001879)2.33225632
64Gangrene (HP:0100758)2.31907071
65Gastrointestinal inflammation (HP:0004386)2.29995788
66Cellulitis (HP:0100658)2.29443418
67Abnormality of the pleura (HP:0002103)2.27427056
68Thrombocytosis (HP:0001894)2.24479352
69Abnormality of macular pigmentation (HP:0008002)2.24332794
70Abnormality of iron homeostasis (HP:0011031)2.20317403
71Hypergammaglobulinemia (HP:0010702)2.17453370
72Stomach cancer (HP:0012126)2.16788297
73Osteomyelitis (HP:0002754)2.13278417
74Keratitis (HP:0000491)2.07388182
75IgM deficiency (HP:0002850)2.06978690
76Hepatosplenomegaly (HP:0001433)2.06157989
77Lymphopenia (HP:0001888)2.06068198
78Increased serum ferritin (HP:0003281)2.05772645
79Sepsis (HP:0100806)2.04397821
80Vertigo (HP:0002321)2.04266643
81Abnormality of transition element cation homeostasis (HP:0011030)2.03544177
82Nasal polyposis (HP:0100582)2.03180797
83Attenuation of retinal blood vessels (HP:0007843)2.02998602
84Cheilitis (HP:0100825)1.95939302
85Autoimmune hemolytic anemia (HP:0001890)1.95193237
86Increased cerebral lipofuscin (HP:0011813)1.93484637
87Abnormality of cells of the lymphoid lineage (HP:0012140)1.89607318
88Abnormality of B cell number (HP:0010975)1.89385304
89Skin rash (HP:0000988)1.88094263
90Autoimmune thrombocytopenia (HP:0001973)1.87938877
91Decreased electroretinogram (ERG) amplitude (HP:0000654)1.87390022
92Hemiplegia (HP:0002301)1.85919011
93IgG deficiency (HP:0004315)1.84795407
94Severe visual impairment (HP:0001141)1.82418861
95Hematochezia (HP:0002573)1.82239463
96Poikilocytosis (HP:0004447)1.82041812
97Glomerulopathy (HP:0100820)1.81965023
98Recurrent sinusitis (HP:0011108)1.81369138
99Abnormality of the pericardium (HP:0001697)1.80713231
100Abnormal platelet volume (HP:0011876)1.79494172

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.16603255
2FES3.83521574
3MAP4K13.38125755
4BLK3.14995302
5MAP2K32.97185001
6KIT2.88148948
7IRAK42.79685661
8GRK62.73323027
9CSK2.56442674
10TXK2.54395190
11TNK22.41124926
12ZAP702.34680590
13CDK192.18915349
14SYK2.16061409
15ERN12.07854140
16BTK2.07034907
17TEC2.04440781
18TYK22.03761304
19JAK31.83502705
20ITK1.71095304
21MAP3K31.66501541
22HCK1.64979548
23TAOK11.62514361
24FGR1.61288579
25LYN1.60773340
26TBK11.59446940
27IKBKE1.58330395
28TAOK31.48036206
29PTK2B1.42060607
30IKBKB1.40457639
31MAP3K141.40337627
32MAP3K111.36392126
33EPHB11.28785358
34MATK1.23589986
35CSF1R1.22814262
36JAK21.22551360
37LCK1.21742913
38FRK1.16951878
39IRAK11.14242822
40SIK31.13323982
41MARK31.10480449
42MAP4K21.10405657
43PRPF4B0.98761563
44SIK20.97196875
45JAK10.87218077
46OXSR10.86691273
47MAP3K70.83197543
48PDK10.81931263
49STK380.80205524
50PIK3CG0.79453495
51PRKCQ0.79184428
52MAP3K10.79025126
53YES10.77614276
54PRKD20.73401448
55DAPK20.70926250
56PIM10.70924682
57NUAK10.70917180
58MARK20.66709196
59MAPK70.64552536
60TAOK20.64423121
61BMPR20.63641736
62FYN0.63491963
63TESK20.61484522
64ADRBK20.61466711
65STK110.61393551
66TRIM280.58996737
67PDPK10.58155474
68MAP2K40.57541121
69STK100.56976352
70INSRR0.53033299
71IRAK20.52896814
72MAP3K130.49947856
73MAP3K50.47640901
74PRKG20.44307119
75ABL10.42447948
76MAP2K60.41984385
77LRRK20.40601925
78PRKCZ0.38717660
79PRKCD0.37828990
80GRK70.37742490
81TGFBR20.36721463
82EPHA30.36496658
83PTK60.36064442
84MAP3K60.36022868
85BCKDK0.34347897
86ADRBK10.34265629
87RPS6KA60.33187474
88MAP2K20.32935786
89RAF10.31585627
90HIPK20.30169037
91KSR20.29969110
92MAPK120.29907794
93RPS6KA40.28015542
94RPS6KL10.27892005
95RPS6KC10.27892005
96WNK30.27286795
97RET0.27113644
98INSR0.23637763
99KSR10.22916126
100PRKAA20.22589632

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.18000566
2Osteoclast differentiation_Homo sapiens_hsa043803.04462388
3Staphylococcus aureus infection_Homo sapiens_hsa051503.00220817
4Graft-versus-host disease_Homo sapiens_hsa053322.84108510
5Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.81580807
6Primary immunodeficiency_Homo sapiens_hsa053402.60492712
7Allograft rejection_Homo sapiens_hsa053302.46559195
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.31289261
9Autoimmune thyroid disease_Homo sapiens_hsa053202.29722280
10NOD-like receptor signaling pathway_Homo sapiens_hsa046212.19338609
11Malaria_Homo sapiens_hsa051442.16052915
12Tuberculosis_Homo sapiens_hsa051522.14865365
13Hematopoietic cell lineage_Homo sapiens_hsa046402.12466684
14Asthma_Homo sapiens_hsa053102.07462467
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.96530702
16B cell receptor signaling pathway_Homo sapiens_hsa046621.88052713
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.87379994
18Legionellosis_Homo sapiens_hsa051341.78617277
19Toll-like receptor signaling pathway_Homo sapiens_hsa046201.76822909
20Type I diabetes mellitus_Homo sapiens_hsa049401.75913810
21Antigen processing and presentation_Homo sapiens_hsa046121.74489914
22Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.71868377
23Measles_Homo sapiens_hsa051621.69358294
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.67179802
25T cell receptor signaling pathway_Homo sapiens_hsa046601.66553691
26Chemokine signaling pathway_Homo sapiens_hsa040621.61439649
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.57432161
28Jak-STAT signaling pathway_Homo sapiens_hsa046301.52333410
29Viral myocarditis_Homo sapiens_hsa054161.43123355
30Acute myeloid leukemia_Homo sapiens_hsa052211.40723279
31African trypanosomiasis_Homo sapiens_hsa051431.36196969
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.32194111
33Phagosome_Homo sapiens_hsa041451.26208946
34Toxoplasmosis_Homo sapiens_hsa051451.25922622
35Platelet activation_Homo sapiens_hsa046111.22131848
36Herpes simplex infection_Homo sapiens_hsa051681.21215259
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.20938890
38Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.18176106
39SNARE interactions in vesicular transport_Homo sapiens_hsa041301.17180969
40Rheumatoid arthritis_Homo sapiens_hsa053231.16483043
41Influenza A_Homo sapiens_hsa051641.16321950
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.14265267
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.12608940
44Regulation of autophagy_Homo sapiens_hsa041401.10529569
45TNF signaling pathway_Homo sapiens_hsa046681.08154060
46Other glycan degradation_Homo sapiens_hsa005111.04354227
47Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99690046
48Leukocyte transendothelial migration_Homo sapiens_hsa046700.99114862
49Shigellosis_Homo sapiens_hsa051310.96602575
50Pertussis_Homo sapiens_hsa051330.89231242
51Non-small cell lung cancer_Homo sapiens_hsa052230.86326143
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86167750
53Arachidonic acid metabolism_Homo sapiens_hsa005900.86036640
54Hepatitis B_Homo sapiens_hsa051610.85857388
55Glycerophospholipid metabolism_Homo sapiens_hsa005640.85124800
56Lysosome_Homo sapiens_hsa041420.81743567
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77799092
58Salmonella infection_Homo sapiens_hsa051320.72737837
59Hepatitis C_Homo sapiens_hsa051600.72099245
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66120080
61Choline metabolism in cancer_Homo sapiens_hsa052310.64619691
62Apoptosis_Homo sapiens_hsa042100.64405306
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.63861450
64Pancreatic cancer_Homo sapiens_hsa052120.62998559
65FoxO signaling pathway_Homo sapiens_hsa040680.62446220
66Phototransduction_Homo sapiens_hsa047440.60534648
67alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59749624
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.58258504
69Linoleic acid metabolism_Homo sapiens_hsa005910.56408352
70Sphingolipid signaling pathway_Homo sapiens_hsa040710.54342762
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54102640
72Olfactory transduction_Homo sapiens_hsa047400.51086089
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.51032762
74Epstein-Barr virus infection_Homo sapiens_hsa051690.49523111
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46715809
76Endocytosis_Homo sapiens_hsa041440.46146620
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.44728297
78Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44482543
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43889094
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.43202330
81VEGF signaling pathway_Homo sapiens_hsa043700.42516115
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.41322469
83Collecting duct acid secretion_Homo sapiens_hsa049660.40327163
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39445104
85Ether lipid metabolism_Homo sapiens_hsa005650.38864693
86MAPK signaling pathway_Homo sapiens_hsa040100.38387866
87Viral carcinogenesis_Homo sapiens_hsa052030.38357310
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37560265
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36318682
90Prolactin signaling pathway_Homo sapiens_hsa049170.36193695
91Chronic myeloid leukemia_Homo sapiens_hsa052200.35422158
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.33981433
93Insulin resistance_Homo sapiens_hsa049310.33486276
94Dorso-ventral axis formation_Homo sapiens_hsa043200.33462099
95Morphine addiction_Homo sapiens_hsa050320.30220698
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28104555
97Notch signaling pathway_Homo sapiens_hsa043300.25579814
98HIF-1 signaling pathway_Homo sapiens_hsa040660.24199839
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.23594679
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.23181556

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »