VGLL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)6.84524653
2chondrocyte proliferation (GO:0035988)6.53616564
3protein heterotrimerization (GO:0070208)5.95990415
4sequestering of extracellular ligand from receptor (GO:0035581)5.83463901
5skin morphogenesis (GO:0043589)5.65071285
6endodermal cell differentiation (GO:0035987)5.19692274
7bone trabecula formation (GO:0060346)5.01522502
8regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)5.00967846
9wound healing, spreading of epidermal cells (GO:0035313)4.94633366
10cell adhesion mediated by integrin (GO:0033627)4.84807385
11axon extension involved in axon guidance (GO:0048846)4.43410845
12neuron projection extension involved in neuron projection guidance (GO:1902284)4.43410845
13positive regulation of endothelial cell apoptotic process (GO:2000353)4.36114403
14wound healing, spreading of cells (GO:0044319)4.21300971
15mesenchymal-epithelial cell signaling (GO:0060638)4.20112836
16negative regulation of fatty acid transport (GO:2000192)4.10549662
17dermatan sulfate biosynthetic process (GO:0030208)4.08135529
18plasma membrane repair (GO:0001778)4.07251675
19regulation of vascular endothelial growth factor signaling pathway (GO:1900746)4.03059092
20collagen metabolic process (GO:0032963)4.00409698
21regulation of tight junction assembly (GO:2000810)3.98782184
22epithelial cell-cell adhesion (GO:0090136)3.93271867
23hippo signaling (GO:0035329)3.91459479
24basement membrane organization (GO:0071711)3.89092261
25collagen catabolic process (GO:0030574)3.88901592
26peptidyl-proline hydroxylation (GO:0019511)3.83302727
27extracellular fibril organization (GO:0043206)3.76441591
28multicellular organismal macromolecule metabolic process (GO:0044259)3.73880420
29estrogen biosynthetic process (GO:0006703)3.70927626
30kidney mesenchyme development (GO:0072074)3.66784200
31dermatan sulfate metabolic process (GO:0030205)3.64718437
32negative regulation of chondrocyte differentiation (GO:0032331)3.64158821
33fibril organization (GO:0097435)3.63545225
34extracellular matrix disassembly (GO:0022617)3.63140563
35pericardium development (GO:0060039)3.56973632
36multicellular organismal catabolic process (GO:0044243)3.55200217
37multicellular organismal metabolic process (GO:0044236)3.52024041
38regulation of transforming growth factor beta1 production (GO:0032908)3.50273549
39protein localization to cell surface (GO:0034394)3.50105857
40craniofacial suture morphogenesis (GO:0097094)3.49629951
41cellular response to vitamin (GO:0071295)3.48791911
42endocardial cushion development (GO:0003197)3.48775861
43desmosome organization (GO:0002934)3.48216004
44cellular response to interferon-alpha (GO:0035457)3.46637544
45metanephric mesenchyme development (GO:0072075)3.42513751
46lymphangiogenesis (GO:0001946)3.40841083
47cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.40489206
48glomerular basement membrane development (GO:0032836)3.39728626
49smooth muscle tissue development (GO:0048745)3.38609214
50positive regulation of macrophage activation (GO:0043032)3.35466592
51regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.34912485
52regulation of axon extension involved in axon guidance (GO:0048841)3.33286302
53negative regulation of axon extension involved in axon guidance (GO:0048843)3.32356679
54positive regulation of epithelial to mesenchymal transition (GO:0010718)3.28240518
55extracellular matrix assembly (GO:0085029)3.27920810
56establishment of skin barrier (GO:0061436)3.24617986
57negative regulation of embryonic development (GO:0045992)3.24010431
58type B pancreatic cell proliferation (GO:0044342)3.23039287
59substrate adhesion-dependent cell spreading (GO:0034446)3.22273063
60positive regulation of blood vessel endothelial cell migration (GO:0043536)3.21614945
61chondrocyte development (GO:0002063)3.21128090
62apoptotic cell clearance (GO:0043277)3.20725438
63regulation of integrin-mediated signaling pathway (GO:2001044)3.20501419
64retina vasculature morphogenesis in camera-type eye (GO:0061299)3.20073560
65myoblast fusion (GO:0007520)3.17220247
66protein hydroxylation (GO:0018126)3.15229970
67negative regulation of catenin import into nucleus (GO:0035414)3.15175789
68planar cell polarity pathway involved in neural tube closure (GO:0090179)3.12376443
69extracellular regulation of signal transduction (GO:1900115)3.10706041
70extracellular negative regulation of signal transduction (GO:1900116)3.10706041
71extracellular matrix organization (GO:0030198)3.08775107
72regulation of axon guidance (GO:1902667)3.08583955
73extracellular structure organization (GO:0043062)3.07526749
74cellular response to vitamin D (GO:0071305)3.05059014
75regulation of water loss via skin (GO:0033561)3.02829987
76regulation of hippo signaling (GO:0035330)3.02152710
77cell migration involved in sprouting angiogenesis (GO:0002042)3.01934625
78G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.00993785
79negative regulation of cartilage development (GO:0061037)3.00752218
80stress fiber assembly (GO:0043149)2.99346215
81positive regulation of osteoblast proliferation (GO:0033690)2.99000784
82cranial suture morphogenesis (GO:0060363)2.97818739
83embryonic cranial skeleton morphogenesis (GO:0048701)2.97323243
84regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.97242060
85vascular endothelial growth factor signaling pathway (GO:0038084)2.94816553
86negative regulation of axon guidance (GO:1902668)2.94349348
87blood vessel maturation (GO:0001955)2.92083673
88negative regulation of smooth muscle cell migration (GO:0014912)2.91721915
89cell migration involved in heart development (GO:0060973)2.90728334
90cell-substrate junction assembly (GO:0007044)2.90602856
91epoxygenase P450 pathway (GO:0019373)2.90490041
92positive regulation of collagen biosynthetic process (GO:0032967)2.89143442
93peptide cross-linking (GO:0018149)2.87361233
94wound healing (GO:0042060)2.86645574
95outer ear morphogenesis (GO:0042473)2.85309064
96establishment of tissue polarity (GO:0007164)2.83982577
97establishment of planar polarity (GO:0001736)2.83982577
98negative regulation of BMP signaling pathway (GO:0030514)2.82876057
99negative chemotaxis (GO:0050919)2.80451141
100positive regulation of collagen metabolic process (GO:0010714)2.79715635
101negative regulation of protein localization to cell surface (GO:2000009)2.78514016
102protein targeting to plasma membrane (GO:0072661)2.75818172
103regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.75789355
104sprouting angiogenesis (GO:0002040)2.74577266
105negative regulation of nitric-oxide synthase activity (GO:0051001)2.74365779
106regulation of gonadotropin secretion (GO:0032276)2.72406831
107positive regulation of mesenchymal cell proliferation (GO:0002053)2.72404324
108regulation of gastrulation (GO:0010470)2.72288203
109face morphogenesis (GO:0060325)2.72145872
110regulation of collagen metabolic process (GO:0010712)2.71220406
111venous blood vessel morphogenesis (GO:0048845)2.71045789
112hemidesmosome assembly (GO:0031581)2.70824401
113positive regulation of fibroblast migration (GO:0010763)2.69608320
114negative regulation of leukocyte chemotaxis (GO:0002689)2.68871811
115peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.68288642
116glomerular visceral epithelial cell development (GO:0072015)2.67649473
117artery development (GO:0060840)2.67583104
118cellular response to amino acid stimulus (GO:0071230)2.67421557
119epithelial to mesenchymal transition (GO:0001837)2.67197532
120syncytium formation by plasma membrane fusion (GO:0000768)2.66781867
121substrate-dependent cell migration (GO:0006929)2.66426287
122polarized epithelial cell differentiation (GO:0030859)2.65823046
123regulation of SMAD protein import into nucleus (GO:0060390)2.65274674
124adherens junction assembly (GO:0034333)2.65181243
125paraxial mesoderm development (GO:0048339)2.64583629
126regulation of collagen biosynthetic process (GO:0032965)2.62219035
127regulation of cartilage development (GO:0061035)2.62104612
128positive regulation of extracellular matrix organization (GO:1903055)2.61492104
129positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.61265035
130syncytium formation (GO:0006949)2.59811696
131axon extension (GO:0048675)2.51596417
132response to follicle-stimulating hormone (GO:0032354)2.51444384
133anterior/posterior axis specification, embryo (GO:0008595)2.50797127
134regulation of mesenchymal cell proliferation (GO:0010464)2.48993587
135neural crest cell development (GO:0014032)2.43910599
136fibroblast migration (GO:0010761)2.43529154
137regulation of chondrocyte differentiation (GO:0032330)2.40702066
138negative regulation of keratinocyte proliferation (GO:0010839)2.39520506
139blood vessel morphogenesis (GO:0048514)2.39390637
140artery morphogenesis (GO:0048844)2.39223097

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.56703298
2TRIM28_21343339_ChIP-Seq_HEK293_Human7.46977783
3RARG_19884340_ChIP-ChIP_MEFs_Mouse5.24658761
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.30332748
5PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.99031613
6* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse3.12936674
7GBX2_23144817_ChIP-Seq_PC3_Human2.90569989
8CLOCK_20551151_ChIP-Seq_293T_Human2.88222269
9TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.79301425
10* CJUN_26792858_Chip-Seq_BT549_Human2.75497806
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.73548342
12SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.64196049
13* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.59380354
14* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.57512431
15WT1_19549856_ChIP-ChIP_CCG9911_Human2.48025809
16BRD4_25478319_ChIP-Seq_HGPS_Human2.39751199
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.36490071
18SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.21560624
19SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.21560624
20HIF1A_21447827_ChIP-Seq_MCF-7_Human2.17741379
21* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.17098011
22* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12591494
23NRF2_20460467_ChIP-Seq_MEFs_Mouse2.08007452
24NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.08007452
25PIAS1_25552417_ChIP-Seq_VCAP_Human2.07167820
26ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.99860040
27ESR1_21235772_ChIP-Seq_MCF-7_Human1.94038112
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.90167750
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.88696957
30PPAR_26484153_Chip-Seq_NCI-H1993_Human1.81284757
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.81135012
32EP300_21415370_ChIP-Seq_HL-1_Mouse1.80919191
33TP53_18474530_ChIP-ChIP_U2OS_Human1.80130166
34NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.79880090
35TP53_20018659_ChIP-ChIP_R1E_Mouse1.79461757
36* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.74577990
37TP53_16413492_ChIP-PET_HCT116_Human1.73929846
38SALL1_21062744_ChIP-ChIP_HESCs_Human1.73407112
39SOX9_24532713_ChIP-Seq_HFSC_Mouse1.70816050
40ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.70407512
41AHR_22903824_ChIP-Seq_MCF-7_Human1.69392656
42SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.69103736
43ELK3_25401928_ChIP-Seq_HUVEC_Human1.68699137
44ATF3_27146783_Chip-Seq_COLON_Human1.67828482
45JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.66882879
46EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.65965538
47JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.63035548
48SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.62965871
49UBF1/2_26484160_Chip-Seq_HMECs_Human1.62630653
50TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.61173765
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.60201701
52SMC1_22415368_ChIP-Seq_MEFs_Mouse1.57785911
53* SMAD4_21799915_ChIP-Seq_A2780_Human1.56069892
54SOX2_20726797_ChIP-Seq_SW620_Human1.55619616
55CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.55391462
56ESR1_15608294_ChIP-ChIP_MCF-7_Human1.54784071
57SALL4_18804426_ChIP-ChIP_XEN_Mouse1.53983613
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53100929
59TP53_22127205_ChIP-Seq_IMR90_Human1.51237111
60ARNT_22903824_ChIP-Seq_MCF-7_Human1.51059986
61SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.50603144
62* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.50165259
63SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.49639336
64SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.49592831
65P300_27058665_Chip-Seq_ZR-75-30cells_Human1.48629398
66TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48169189
67POU3F2_20337985_ChIP-ChIP_501MEL_Human1.48154399
68FOXO3_23340844_ChIP-Seq_DLD1_Human1.46885473
69SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.46538207
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.46435638
71HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.46345392
72ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45546647
73SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44784016
74MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.42371388
75* P300_19829295_ChIP-Seq_ESCs_Human1.42244313
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.39978953
77BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.38306156
78SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36758789
79* TP53_23651856_ChIP-Seq_MEFs_Mouse1.36178461
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.35715396
81KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31187188
82RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30834448
83HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.29898862
84CTNNB1_20460455_ChIP-Seq_HCT116_Human1.29335940
85* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28895387
86FUS_26573619_Chip-Seq_HEK293_Human1.28293843
87MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.26659622
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.25353318
89JARID2_20064375_ChIP-Seq_MESCs_Mouse1.25246911
90SMAD3_21741376_ChIP-Seq_EPCs_Human1.24815890
91RNF2_27304074_Chip-Seq_ESCs_Mouse1.24291802
92STAT3_23295773_ChIP-Seq_U87_Human1.24286809
93RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.23617183
94* TAF15_26573619_Chip-Seq_HEK293_Human1.23477188
95PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.22578594
96ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.22452283
97EZH2_27304074_Chip-Seq_ESCs_Mouse1.22007684
98* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21441874
99UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21119692
100PCGF2_27294783_Chip-Seq_ESCs_Mouse1.20787678
101TBX3_20139965_ChIP-Seq_MESCs_Mouse1.20506564
102TBX3_20139965_ChIP-Seq_ESCs_Mouse1.20210187
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20040316
104TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.19048836
105PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18860508
106NFI_21473784_ChIP-Seq_ESCs_Mouse1.18650793
107SMC3_22415368_ChIP-Seq_MEFs_Mouse1.16483312
108TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.16166828
109KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15119696
110* ELK1_22589737_ChIP-Seq_MCF10A_Human1.15049328
111MTF2_20144788_ChIP-Seq_MESCs_Mouse1.14716915
112JARID2_20075857_ChIP-Seq_MESCs_Mouse1.14568349
113RACK7_27058665_Chip-Seq_MCF-7_Human1.14124249
114EED_16625203_ChIP-ChIP_MESCs_Mouse1.13824357
115FLI1_27457419_Chip-Seq_LIVER_Mouse1.13417274
116KDM2B_26808549_Chip-Seq_REH_Human1.13361411
117PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.12205083
118KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12062003
119ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11893523
120* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11643066
121SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11362425
122EZH2_22144423_ChIP-Seq_EOC_Human1.11284149
123KLF5_25053715_ChIP-Seq_YYC3_Human1.10171503
124NANOG_18555785_Chip-Seq_ESCs_Mouse1.09177610
125WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09044591
126AR_25329375_ChIP-Seq_VCAP_Human1.07995767
127NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.06879637
128* EWS_26573619_Chip-Seq_HEK293_Human1.06875959
129YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06660295
130SMAD3_21741376_ChIP-Seq_HESCs_Human1.05583200
131SA1_22415368_ChIP-Seq_MEFs_Mouse1.04789283
132FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03392809
133EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03258628
134EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.02611278
135BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.02318284
136TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02042271
137FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.98389906
138TBX20_22080862_ChIP-Seq_HEART_Mouse0.96048228
139TBX20_22328084_ChIP-Seq_HEART_Mouse0.96048228
140ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.94365252
141TCF4_18268006_ChIP-ChIP_LS174T_Human0.94027618
142TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93817206
143ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.93502240
144* TP63_23658742_ChIP-Seq_EP156T_Human0.93344394
145TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92229814
146PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.91944905
147PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.87390174
148KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.86001851
149ZFP281_18757296_ChIP-ChIP_E14_Mouse0.85865354
150AR_21909140_ChIP-Seq_LNCAP_Human0.85317207
151RNF2_18974828_ChIP-Seq_MESCs_Mouse0.85278966
152EZH2_18974828_ChIP-Seq_MESCs_Mouse0.85278966
153PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.84111746
154RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.83951073
155TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.83882895
156STAT6_21828071_ChIP-Seq_BEAS2B_Human0.82666009
157TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.80789979
158GATA2_21666600_ChIP-Seq_HMVEC_Human0.80597626
159FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.79817325
160ISL1_27105846_Chip-Seq_CPCs_Mouse0.78765139
161NANOG_16153702_ChIP-ChIP_HESCs_Human0.78074501

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen7.93809349
2MP0005275_abnormal_skin_tensile6.06367455
3MP0003705_abnormal_hypodermis_morpholog4.50854641
4MP0005503_abnormal_tendon_morphology4.48688257
5MP0003279_aneurysm3.78803283
6MP0001958_emphysema3.04875979
7MP0009384_cardiac_valve_regurgitation3.02079354
8MP0005623_abnormal_meninges_morphology2.92120427
9MP0004272_abnormal_basement_membrane2.80416984
10MP0003941_abnormal_skin_development2.47656991
11MP0002060_abnormal_skin_morphology2.43711824
12MP0010352_gastrointestinal_tract_polyps2.37603230
13MP0003566_abnormal_cell_adhesion2.32497189
14MP0006054_spinal_hemorrhage2.23965170
15MP0005508_abnormal_skeleton_morphology2.02445111
16MP0005023_abnormal_wound_healing1.96897581
17MP0010030_abnormal_orbit_morphology1.93169058
18MP0009780_abnormal_chondrocyte_physiolo1.91397021
19MP0005257_abnormal_intraocular_pressure1.87030364
20MP0003091_abnormal_cell_migration1.82533540
21MP0002295_abnormal_pulmonary_circulatio1.80549229
22MP0002796_impaired_skin_barrier1.74221369
23MP0001542_abnormal_bone_strength1.71695954
24MP0010386_abnormal_urinary_bladder1.64346869
25MP0000013_abnormal_adipose_tissue1.64039145
26MP0003385_abnormal_body_wall1.62979715
27MP0001243_abnormal_dermal_layer1.62512312
28MP0009250_abnormal_appendicular_skeleto1.60917648
29MP0000733_abnormal_muscle_development1.57837379
30MP0000569_abnormal_digit_pigmentation1.50875013
31MP0010234_abnormal_vibrissa_follicle1.47738151
32MP0002108_abnormal_muscle_morphology1.47522847
33MP0001299_abnormal_eye_distance/1.46119392
34MP0003950_abnormal_plasma_membrane1.42831514
35MP0005501_abnormal_skin_physiology1.32244751
36MP0009053_abnormal_anal_canal1.29996064
37MP0002896_abnormal_bone_mineralization1.29350248
38MP0000750_abnormal_muscle_regeneration1.25573862
39MP0002877_abnormal_melanocyte_morpholog1.23868156
40MP0003942_abnormal_urinary_system1.17868694
41MP0000767_abnormal_smooth_muscle1.17717577
42MP0003045_fibrosis1.14333669
43MP0001348_abnormal_lacrimal_gland1.11251793
44MP0005390_skeleton_phenotype1.10148235
45MP0003755_abnormal_palate_morphology1.08593203
46MP0002168_other_aberrant_phenotype1.07390677
47MP0002282_abnormal_trachea_morphology1.06770193
48MP0005076_abnormal_cell_differentiation1.04917704
49MP0010771_integument_phenotype1.04592957
50MP0004858_abnormal_nervous_system1.04215895
51MP0000163_abnormal_cartilage_morphology1.01266873
52MP0000534_abnormal_ureter_morphology0.98546384
53MP0000428_abnormal_craniofacial_morphol0.97803831
54MP0002932_abnormal_joint_morphology0.97347135
55MP0009697_abnormal_copulation0.96744816
56MP0000003_abnormal_adipose_tissue0.96300861
57MP0002115_abnormal_skeleton_extremities0.94150428
58MP0010368_abnormal_lymphatic_system0.93835278
59MP0000538_abnormal_urinary_bladder0.90239442
60MP0003115_abnormal_respiratory_system0.89618226
61MP0002933_joint_inflammation0.87841967
62MP0004233_abnormal_muscle_weight0.87698829
63MP0004134_abnormal_chest_morphology0.86455563
64MP0000778_abnormal_nervous_system0.84127257
65MP0002113_abnormal_skeleton_development0.84003821
66MP0000432_abnormal_head_morphology0.81875214
67MP0002938_white_spotting0.81806814
68MP0000762_abnormal_tongue_morphology0.81324519
69MP0006276_abnormal_autonomic_nervous0.81065824
70MP0000462_abnormal_digestive_system0.80892883
71MP0003283_abnormal_digestive_organ0.79629662
72MP0000749_muscle_degeneration0.76505573
73MP0002128_abnormal_blood_circulation0.76448482
74MP0000759_abnormal_skeletal_muscle0.75451133
75MP0002111_abnormal_tail_morphology0.75153536
76MP0005595_abnormal_vascular_smooth0.74926411
77MP0002249_abnormal_larynx_morphology0.73712251
78MP0000858_altered_metastatic_potential0.73067733
79MP0001216_abnormal_epidermal_layer0.72381036
80MP0000516_abnormal_urinary_system0.72349321
81MP0005367_renal/urinary_system_phenotyp0.72349321
82MP0002177_abnormal_outer_ear0.72338492
83MP0003453_abnormal_keratinocyte_physiol0.72069980
84MP0000751_myopathy0.71772574
85MP0004084_abnormal_cardiac_muscle0.71258705
86MP0003937_abnormal_limbs/digits/tail_de0.70732987
87MP0001614_abnormal_blood_vessel0.70653516
88MP0001879_abnormal_lymphatic_vessel0.70371650
89MP0002089_abnormal_postnatal_growth/wei0.68694714
90MP0003935_abnormal_craniofacial_develop0.68426125
91MP0000049_abnormal_middle_ear0.68327095
92MP0000537_abnormal_urethra_morphology0.68022395
93MP0000467_abnormal_esophagus_morphology0.67948942
94MP0001177_atelectasis0.67936730
95MP0002109_abnormal_limb_morphology0.67222907
96MP0001915_intracranial_hemorrhage0.67180028
97MP0005388_respiratory_system_phenotype0.66549015
98MP0002133_abnormal_respiratory_system0.66549015
99MP0002233_abnormal_nose_morphology0.66276873
100MP0002116_abnormal_craniofacial_bone0.65588658
101MP0005171_absent_coat_pigmentation0.65280523
102MP0004087_abnormal_muscle_fiber0.64998497
103MP0005375_adipose_tissue_phenotype0.64471200
104MP0000230_abnormal_systemic_arterial0.63554464
105MP0006138_congestive_heart_failure0.62957872
106MP0002234_abnormal_pharynx_morphology0.62217341
107MP0005620_abnormal_muscle_contractility0.62114679
108MP0004185_abnormal_adipocyte_glucose0.61758721
109MP0002998_abnormal_bone_remodeling0.61645796
110MP0009931_abnormal_skin_appearance0.61604476
111MP0001533_abnormal_skeleton_physiology0.61155885
112MP0002114_abnormal_axial_skeleton0.60949092
113MP0000377_abnormal_hair_follicle0.60639528
114MP0005369_muscle_phenotype0.60322400
115MP0005193_abnormal_anterior_eye0.60117975
116MP0005197_abnormal_uvea_morphology0.58795460
117MP0004197_abnormal_fetal_growth/weight/0.58584795
118MP0002925_abnormal_cardiovascular_devel0.57426153
119MP0001175_abnormal_lung_morphology0.55876003
120MP0002697_abnormal_eye_size0.55208907
121MP0003959_abnormal_lean_body0.54959050
122MP0004859_abnormal_synaptic_plasticity0.51886123
123MP0002184_abnormal_innervation0.49036908

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)8.81773744
2Premature rupture of membranes (HP:0001788)8.66220761
3Aortic dissection (HP:0002647)5.04327325
4Peritonitis (HP:0002586)4.91015383
5Shallow orbits (HP:0000586)4.80695180
6Soft skin (HP:0000977)4.78533863
7Atrophic scars (HP:0001075)4.72013685
8Ankle contracture (HP:0006466)4.55702890
9Aortic aneurysm (HP:0004942)4.43107325
10Dilatation of the ascending aorta (HP:0005111)4.33300242
11Abnormality of dentin (HP:0010299)4.15550600
12Fragile skin (HP:0001030)4.12568852
13Cerebral aneurysm (HP:0004944)4.02570820
14Bladder diverticulum (HP:0000015)3.94483159
15Cervical subluxation (HP:0003308)3.79642701
16Wormian bones (HP:0002645)3.70146007
17Vertebral compression fractures (HP:0002953)3.64563164
18Genu recurvatum (HP:0002816)3.64433276
19Broad metatarsal (HP:0001783)3.55624286
20Neonatal short-limb short stature (HP:0008921)3.47862335
21Wrist flexion contracture (HP:0001239)3.45653148
22Spinal rigidity (HP:0003306)3.40384853
23Biconcave vertebral bodies (HP:0004586)3.38128159
24Blue sclerae (HP:0000592)3.35952288
25Mitral valve prolapse (HP:0001634)3.31619699
26Type 1 muscle fiber predominance (HP:0003803)3.27482751
27Aortic regurgitation (HP:0001659)3.25912504
28Increased connective tissue (HP:0009025)3.20623796
29Vascular tortuosity (HP:0004948)3.12062303
30Morphological abnormality of the middle ear (HP:0008609)3.06395650
31Bowel diverticulosis (HP:0005222)2.97961686
32Abnormal delivery (HP:0001787)2.90886688
33Follicular hyperkeratosis (HP:0007502)2.87728610
34Mild short stature (HP:0003502)2.84907617
35Overgrowth (HP:0001548)2.81154305
36Short nail (HP:0001799)2.77336497
37Hypoplasia of the iris (HP:0007676)2.75018032
38Hyperextensible skin (HP:0000974)2.69849922
39Round ear (HP:0100830)2.66705427
40Infantile muscular hypotonia (HP:0008947)2.61152594
41Elbow flexion contracture (HP:0002987)2.59857700
42Abnormality of the acetabulum (HP:0003170)2.52817609
43Thin bony cortex (HP:0002753)2.51610155
44Osteolytic defects of the hand bones (HP:0009699)2.51483568
45Osteolytic defects of the phalanges of the hand (HP:0009771)2.51483568
46Breech presentation (HP:0001623)2.49733336
47Abnormality of the ischium (HP:0003174)2.48807428
48Arterial tortuosity (HP:0005116)2.43998106
49Increased corneal curvature (HP:0100692)2.40120878
50Keratoconus (HP:0000563)2.40120878
51Mildly elevated creatine phosphokinase (HP:0008180)2.37037961
52Aortic valve stenosis (HP:0001650)2.35895552
53Camptodactyly of toe (HP:0001836)2.34311283
54Aneurysm (HP:0002617)2.34197411
55Increased variability in muscle fiber diameter (HP:0003557)2.31485327
56Difficulty climbing stairs (HP:0003551)2.29913413
57Absent frontal sinuses (HP:0002688)2.28395567
58Wide anterior fontanel (HP:0000260)2.25270753
59Delayed gross motor development (HP:0002194)2.24907463
60Mitral regurgitation (HP:0001653)2.24368553
61Striae distensae (HP:0001065)2.21796412
62Mitral stenosis (HP:0001718)2.19972234
63Distal upper limb amyotrophy (HP:0007149)2.19465101
64Upper limb amyotrophy (HP:0009129)2.19465101
65Slender build (HP:0001533)2.19090337
66Ectopia lentis (HP:0001083)2.16046432
67Spinal cord lesions (HP:0100561)2.15515635
68Syringomyelia (HP:0003396)2.15515635
69Abnormality of the peritoneum (HP:0002585)2.15337001
70Tibial bowing (HP:0002982)2.14329739
71Deviation of the hallux (HP:0010051)2.12516740
72Flat cornea (HP:0007720)2.11641680
73Joint laxity (HP:0001388)2.11117109
74Limited hip movement (HP:0008800)2.09636663
75Increased density of long bones (HP:0006392)2.08668968
76Abnormality of skeletal muscle fiber size (HP:0012084)2.08631182
77Abnormality of the calcaneus (HP:0008364)2.08522374
78Osteoarthritis (HP:0002758)2.07877344
79Bell-shaped thorax (HP:0001591)2.06584521
80Right ventricular cardiomyopathy (HP:0011663)2.06194325
81Scapular winging (HP:0003691)2.06044591
82Mesomelia (HP:0003027)2.05739685
83Spondylolisthesis (HP:0003302)2.05672310
84Hallux valgus (HP:0001822)2.05035250
85Knee flexion contracture (HP:0006380)2.03951039
86Buphthalmos (HP:0000557)2.03750533
87Venous abnormality (HP:0002624)2.01968577
88Distal lower limb amyotrophy (HP:0008944)1.97513155
89Coronal craniosynostosis (HP:0004440)1.97361434
90Coxa vara (HP:0002812)1.96293262
91Hypoplastic ischia (HP:0003175)1.96010773
92Deformed tarsal bones (HP:0008119)1.92998824
93Hyporeflexia of lower limbs (HP:0002600)1.90781651
94Calcaneovalgus deformity (HP:0001848)1.88133953
95Venous insufficiency (HP:0005293)1.86933960
96Broad ribs (HP:0000885)1.86868643
97Joint contractures involving the joints of the feet (HP:0100492)1.86373077
98Flexion contracture of toe (HP:0005830)1.86373077
99Upper limb muscle weakness (HP:0003484)1.80570687
100Radial bowing (HP:0002986)1.80358024
101Tarsal synostosis (HP:0008368)1.79942555
102Natal tooth (HP:0000695)1.78638576
103Nonimmune hydrops fetalis (HP:0001790)1.78387195
104Femoral bowing (HP:0002980)1.77853902
105Decreased skull ossification (HP:0004331)1.77059285
106Congenital glaucoma (HP:0001087)1.77056102
107Hypoventilation (HP:0002791)1.76108936
108Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.75805440
109Achilles tendon contracture (HP:0001771)1.75713943
110Redundant skin (HP:0001582)1.75124331
111Inguinal hernia (HP:0000023)1.74583471
112Delayed cranial suture closure (HP:0000270)1.73434761
113Protruding ear (HP:0000411)1.72187008
114Joint stiffness (HP:0001387)1.71808576
115Hip contracture (HP:0003273)1.71052667
116Spinal cord compression (HP:0002176)1.70399640
117Pterygium (HP:0001059)1.70042022
118Pulmonic stenosis (HP:0001642)1.69207421
119Trismus (HP:0000211)1.68881581
120Broad long bones (HP:0005622)1.67956821
121Ulnar bowing (HP:0003031)1.67608632
122Thin skin (HP:0000963)1.67600615
123Abnormality of skull ossification (HP:0002703)1.64970169
124Vertebral arch anomaly (HP:0008438)1.63924519
125Aplasia of the musculature (HP:0100854)1.63572064
126Thin ribs (HP:0000883)1.62730824
127Pulmonary artery stenosis (HP:0004415)1.60631207
128Cardiovascular calcification (HP:0011915)1.57621264
129Narrow palate (HP:0000189)1.57324915
130Pectus carinatum (HP:0000768)1.55394695
131Renovascular hypertension (HP:0100817)1.55391230

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.20178673
2TTN3.93442647
3LATS23.88970139
4TRIB33.82295778
5LATS13.04567311
6PDGFRA2.98256510
7EPHB22.87567138
8TESK12.78744197
9AKT32.72689860
10MARK12.42779716
11LIMK12.22879935
12ERN12.21715029
13PAK22.21696766
14TRPM72.18509518
15TNIK2.11594753
16EPHA22.07128705
17FER2.03221787
18PAK32.02563471
19PTK21.91661704
20MOS1.89119622
21PIM21.89095775
22PKN21.80632683
23ERBB31.61811744
24CASK1.60204876
25BCR1.59430349
26RPS6KA41.56943667
27LRRK21.56281750
28EPHA31.55043849
29BMX1.52592226
30PIK3CG1.52406131
31FGFR11.50794632
32MUSK1.47688096
33SIK11.47139777
34STK381.44583742
35BRD41.39126523
36STK31.32866361
37RIPK11.31607475
38DMPK1.29470139
39MET1.28430304
40PIK3CA1.27003194
41PAK41.26386361
42PTK2B1.26320985
43NEK91.25500079
44ROCK11.24267074
45MAPKAPK31.23143112
46PTK61.19074934
47TESK21.19070725
48NTRK11.18919088
49ILK1.18028568
50NME21.17949397
51FRK1.10297872
52MAP2K11.09834229
53WNK11.02255590
54FLT31.01035371
55STK38L1.00982768
56MTOR0.97035862
57ADRBK20.93366053
58PRKCE0.90154701
59MAP3K30.88185753
60KIT0.85406536
61PDGFRB0.81695812
62BMPR1B0.79265506
63RPS6KA20.79072634
64CDK60.79017189
65PNCK0.78715518
66PAK10.77890169
67MYLK0.77489356
68TGFBR20.72990209
69ROCK20.72760288
70STK100.70237189
71ABL20.69415234
72MAP3K70.68164487
73PRKD30.65423868
74INSR0.64093359
75PLK20.63951325
76EEF2K0.61827045
77GSK3A0.61741836
78CAMK1G0.60649675
79CDK140.60236699
80NEK20.59869994
81GRK10.59776403
82RAF10.59537229
83DAPK30.58494741
84NUAK10.57746051
85RPS6KB20.57691728
86MAP3K80.56876174
87MELK0.56464090
88ZAK0.56342753
89SCYL20.54401132
90CDK150.52100050
91PRKD10.51169694
92CDK120.50946802
93CDK180.49843190
94PRKD20.49347043
95CAMK2B0.47241254
96DYRK1B0.46628648
97CDK11A0.45004608
98EPHB10.44731888
99CAMK2G0.44585460
100STK390.44578948
101CAMK2D0.44362474
102PDK30.43918149
103PDK40.43918149
104PDK20.41684746
105CDC42BPA0.41346111
106SRC0.40560079
107RET0.40555998
108PRKCG0.40169154
109TAOK10.40106882
110MAP3K60.39763691
111NTRK20.38572375
112MAPKAPK50.38298335
113MAPKAPK20.37765541
114MAPK70.36855099
115MST1R0.36823276
116BRSK20.35771308
117AURKA0.34492226
118GRK70.33951060
119SGK20.33626542
120AURKB0.33022283
121ADRBK10.32509071
122PRKG20.32495414
123PKN10.32416025
124CAMK2A0.31589918
125MAP3K100.31554193
126ERBB20.31338763
127PRKG10.30994283
128LMTK20.30498313
129ERBB40.30371333
130TAOK20.29941645
131ABL10.28610381
132PRKCH0.28589818
133MAP2K30.28056494
134CDK80.26786214
135PINK10.26695480
136WNK40.26494120
137RPS6KA60.25895588
138TGFBR10.25009257
139DAPK20.24315519
140RPS6KC10.24231356
141RPS6KL10.24231356
142JAK10.23896354
143SGK30.23395985
144MAP3K50.22958228
145PAK60.21568709
146IGF1R0.21025683
147MAPK10.20794302

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.33746169
2Focal adhesion_Homo sapiens_hsa045103.29521450
3Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.71281045
4Proteoglycans in cancer_Homo sapiens_hsa052052.65662904
5Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.61875653
6Adherens junction_Homo sapiens_hsa045202.55622267
7Bladder cancer_Homo sapiens_hsa052192.42652211
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.40728736
9Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.35467000
10Hippo signaling pathway_Homo sapiens_hsa043902.27232018
11TGF-beta signaling pathway_Homo sapiens_hsa043502.23605578
12Amoebiasis_Homo sapiens_hsa051462.22346338
13AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.12239273
14p53 signaling pathway_Homo sapiens_hsa041152.12081326
15Dilated cardiomyopathy_Homo sapiens_hsa054142.09935786
16MicroRNAs in cancer_Homo sapiens_hsa052062.06842315
17Malaria_Homo sapiens_hsa051442.05759799
18Protein digestion and absorption_Homo sapiens_hsa049742.01296526
19Small cell lung cancer_Homo sapiens_hsa052221.99464538
20Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.74136388
21Tight junction_Homo sapiens_hsa045301.70101289
22Melanoma_Homo sapiens_hsa052181.68329458
23Regulation of actin cytoskeleton_Homo sapiens_hsa048101.67898771
24Basal cell carcinoma_Homo sapiens_hsa052171.64814109
25Shigellosis_Homo sapiens_hsa051311.62384022
26PI3K-Akt signaling pathway_Homo sapiens_hsa041511.62196996
27Chronic myeloid leukemia_Homo sapiens_hsa052201.52489208
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.50252229
29Hedgehog signaling pathway_Homo sapiens_hsa043401.43308800
30Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.37052075
31Viral myocarditis_Homo sapiens_hsa054161.36834135
32Dorso-ventral axis formation_Homo sapiens_hsa043201.34397803
33Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.33824926
34Glioma_Homo sapiens_hsa052141.24503455
35Rap1 signaling pathway_Homo sapiens_hsa040151.16919108
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.16480943
37Prostate cancer_Homo sapiens_hsa052151.14399061
38Axon guidance_Homo sapiens_hsa043601.14051202
39Pathways in cancer_Homo sapiens_hsa052001.10499105
40Steroid hormone biosynthesis_Homo sapiens_hsa001401.04170686
41cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02080996
42Platelet activation_Homo sapiens_hsa046111.00590231
43Pancreatic cancer_Homo sapiens_hsa052120.99042223
44Wnt signaling pathway_Homo sapiens_hsa043100.98591632
45HTLV-I infection_Homo sapiens_hsa051660.98030813
46Phagosome_Homo sapiens_hsa041450.96875380
47Salmonella infection_Homo sapiens_hsa051320.96566804
48TNF signaling pathway_Homo sapiens_hsa046680.91141077
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.85349504
50Glutamatergic synapse_Homo sapiens_hsa047240.84352817
51Renal cell carcinoma_Homo sapiens_hsa052110.84282224
52Endocytosis_Homo sapiens_hsa041440.83287306
53HIF-1 signaling pathway_Homo sapiens_hsa040660.80462603
54Toxoplasmosis_Homo sapiens_hsa051450.80338860
55Viral carcinogenesis_Homo sapiens_hsa052030.80119888
56Circadian entrainment_Homo sapiens_hsa047130.79364092
57Apoptosis_Homo sapiens_hsa042100.78914403
58cAMP signaling pathway_Homo sapiens_hsa040240.78894192
59Cocaine addiction_Homo sapiens_hsa050300.78539532
60Melanogenesis_Homo sapiens_hsa049160.76043727
61Circadian rhythm_Homo sapiens_hsa047100.75794174
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.74682409
63Aldosterone synthesis and secretion_Homo sapiens_hsa049250.74098445
64Ras signaling pathway_Homo sapiens_hsa040140.73968925
65Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71560628
66Gap junction_Homo sapiens_hsa045400.71315362
67Salivary secretion_Homo sapiens_hsa049700.71289095
68Oxytocin signaling pathway_Homo sapiens_hsa049210.71121619
69Calcium signaling pathway_Homo sapiens_hsa040200.71109093
70Renin secretion_Homo sapiens_hsa049240.71065695
71Central carbon metabolism in cancer_Homo sapiens_hsa052300.70258823
72Long-term depression_Homo sapiens_hsa047300.69727756
73ErbB signaling pathway_Homo sapiens_hsa040120.69305348
74Cholinergic synapse_Homo sapiens_hsa047250.68251950
75Cell cycle_Homo sapiens_hsa041100.67331253
76mTOR signaling pathway_Homo sapiens_hsa041500.65967964
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.65000505
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.64369519
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.61993718
80Hepatitis B_Homo sapiens_hsa051610.60736555
81Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.60671090
82Vascular smooth muscle contraction_Homo sapiens_hsa042700.59661530
83Nicotine addiction_Homo sapiens_hsa050330.59589679
84Endometrial cancer_Homo sapiens_hsa052130.59011628
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58817966
86VEGF signaling pathway_Homo sapiens_hsa043700.58369734
87Sphingolipid metabolism_Homo sapiens_hsa006000.57569921
88Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55828850
89Colorectal cancer_Homo sapiens_hsa052100.54779121
90Thyroid cancer_Homo sapiens_hsa052160.54341418
91FoxO signaling pathway_Homo sapiens_hsa040680.53960466
92Taste transduction_Homo sapiens_hsa047420.53373724
93Lysine degradation_Homo sapiens_hsa003100.52617963
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51818091
95Estrogen signaling pathway_Homo sapiens_hsa049150.51794255
96Dopaminergic synapse_Homo sapiens_hsa047280.51472951
97Insulin secretion_Homo sapiens_hsa049110.48150633
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.47995794
99Selenocompound metabolism_Homo sapiens_hsa004500.47643464
100MAPK signaling pathway_Homo sapiens_hsa040100.47577705
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.47550594
102GnRH signaling pathway_Homo sapiens_hsa049120.47211829
103Primary bile acid biosynthesis_Homo sapiens_hsa001200.47206840
104N-Glycan biosynthesis_Homo sapiens_hsa005100.46850042
105Morphine addiction_Homo sapiens_hsa050320.46736954
106Arachidonic acid metabolism_Homo sapiens_hsa005900.46629756
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.46447391
108Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.46216577
109Phospholipase D signaling pathway_Homo sapiens_hsa040720.46035734
110Glutathione metabolism_Homo sapiens_hsa004800.45850715
111GABAergic synapse_Homo sapiens_hsa047270.45726013
112Renin-angiotensin system_Homo sapiens_hsa046140.45712680
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45677715
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44890961
115Pertussis_Homo sapiens_hsa051330.44285072
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43322192
117Gastric acid secretion_Homo sapiens_hsa049710.42103043
118ABC transporters_Homo sapiens_hsa020100.41959893
119AMPK signaling pathway_Homo sapiens_hsa041520.41930124
120Prolactin signaling pathway_Homo sapiens_hsa049170.41257836
121Ovarian steroidogenesis_Homo sapiens_hsa049130.38391518
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.37688028
123Lysosome_Homo sapiens_hsa041420.37501167
124Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.37234824
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34821832
126Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.32894416
127Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32651183
128Thyroid hormone synthesis_Homo sapiens_hsa049180.29880131
129Insulin signaling pathway_Homo sapiens_hsa049100.29384523
130One carbon pool by folate_Homo sapiens_hsa006700.28647500
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.28565282
132Non-small cell lung cancer_Homo sapiens_hsa052230.27325037
133Vibrio cholerae infection_Homo sapiens_hsa051100.26300677

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