VEPH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron fate determination (GO:0048664)4.73205440
2axon ensheathment in central nervous system (GO:0032291)4.47099853
3central nervous system myelination (GO:0022010)4.47099853
4presynaptic membrane assembly (GO:0097105)4.32311586
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.28604111
6protein neddylation (GO:0045116)4.22976503
7superoxide anion generation (GO:0042554)4.15321832
8radial glial cell differentiation (GO:0060019)4.03701076
9sequestering of actin monomers (GO:0042989)3.97972223
10presynaptic membrane organization (GO:0097090)3.86402846
11limb bud formation (GO:0060174)3.74012230
12polyol transport (GO:0015791)3.55826724
13regulation of integrin-mediated signaling pathway (GO:2001044)3.54299524
14mesenchymal cell differentiation involved in kidney development (GO:0072161)3.53276528
15mesenchymal cell differentiation involved in renal system development (GO:2001012)3.53276528
16negative regulation of protein localization to cell surface (GO:2000009)3.47488019
17negative regulation of astrocyte differentiation (GO:0048712)3.46268858
18regulation of somitogenesis (GO:0014807)3.43650523
19artery development (GO:0060840)3.39217084
20intraciliary transport (GO:0042073)3.37990186
21regulation of timing of cell differentiation (GO:0048505)3.37641909
22cerebral cortex radially oriented cell migration (GO:0021799)3.37553069
23epithelial cilium movement (GO:0003351)3.37523916
24long-chain fatty acid biosynthetic process (GO:0042759)3.30000665
25startle response (GO:0001964)3.25770962
26negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.25523746
27retinal ganglion cell axon guidance (GO:0031290)3.24696521
28neuronal stem cell maintenance (GO:0097150)3.24399990
29positive regulation of endothelial cell differentiation (GO:0045603)3.20652433
30oligosaccharide catabolic process (GO:0009313)3.20445591
31righting reflex (GO:0060013)3.17334289
32cell proliferation in forebrain (GO:0021846)3.16584171
33negative regulation of myoblast differentiation (GO:0045662)3.16251150
34keratinocyte development (GO:0003334)3.15460919
35positive regulation of oligodendrocyte differentiation (GO:0048714)3.15107466
36somite development (GO:0061053)3.13214995
37otic vesicle formation (GO:0030916)3.11408171
38negative chemotaxis (GO:0050919)3.09091026
39developmental pigmentation (GO:0048066)3.08739072
40postsynaptic membrane organization (GO:0001941)3.06968446
41regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.04392146
42platelet dense granule organization (GO:0060155)3.03355861
43chondrocyte proliferation (GO:0035988)2.97726373
44positive regulation of male gonad development (GO:2000020)2.95784525
45microtubule polymerization or depolymerization (GO:0031109)2.94250599
46nonmotile primary cilium assembly (GO:0035058)2.90127963
47cell differentiation involved in metanephros development (GO:0072202)2.90071425
48regulation of development, heterochronic (GO:0040034)2.89031208
49G-protein coupled receptor internalization (GO:0002031)2.88166100
50smoothened signaling pathway (GO:0007224)2.86429765
51neuron cell-cell adhesion (GO:0007158)2.86088809
52cranial nerve morphogenesis (GO:0021602)2.85029552
53female gonad development (GO:0008585)2.84486415
54reflex (GO:0060004)2.83770193
55GPI anchor metabolic process (GO:0006505)2.82272192
56aminoglycoside antibiotic metabolic process (GO:0030647)2.81842523
57GPI anchor biosynthetic process (GO:0006506)2.81800236
58cilium morphogenesis (GO:0060271)2.81460434
59pyrimidine nucleobase catabolic process (GO:0006208)2.81306884
60negative regulation of keratinocyte proliferation (GO:0010839)2.80292644
61cilium organization (GO:0044782)2.78686886
62preassembly of GPI anchor in ER membrane (GO:0016254)2.77341017
63cilium assembly (GO:0042384)2.76499766
64lymphangiogenesis (GO:0001946)2.75972259
65positive regulation of neuroblast proliferation (GO:0002052)2.74808913
66detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.74062934
67myelin assembly (GO:0032288)2.73264820
68spermatid nucleus differentiation (GO:0007289)2.72094931
69astrocyte differentiation (GO:0048708)2.71917720
70vascular smooth muscle contraction (GO:0014829)2.71037666
71kidney morphogenesis (GO:0060993)2.70806236
72cilium movement (GO:0003341)2.69989925
73regulation of non-canonical Wnt signaling pathway (GO:2000050)2.69682404
74retinal rod cell development (GO:0046548)2.69452297
75cholesterol biosynthetic process (GO:0006695)2.69203694
76cellular response to cholesterol (GO:0071397)2.68857873
77neuron remodeling (GO:0016322)2.68608848
78tongue development (GO:0043586)2.68510187
79import into cell (GO:0098657)2.67606085
80neural crest cell development (GO:0014032)2.67381370
81regulation of oligodendrocyte differentiation (GO:0048713)2.66878859
82negative regulation of execution phase of apoptosis (GO:1900118)2.66400561
83positive regulation of action potential (GO:0045760)2.65672214
84limb development (GO:0060173)2.65122779
85appendage development (GO:0048736)2.65122779
86centriole replication (GO:0007099)2.64301154
87negative regulation of osteoblast proliferation (GO:0033689)2.62511633
88regulation of lipoprotein metabolic process (GO:0050746)2.61510762
89negative regulation of synaptic transmission, GABAergic (GO:0032229)2.60166093
90cell differentiation involved in kidney development (GO:0061005)2.59947985
91regulation of mesenchymal cell apoptotic process (GO:2001053)2.57344071
92metaphase plate congression (GO:0051310)2.57254400
93inner ear receptor stereocilium organization (GO:0060122)2.56088851
94sterol biosynthetic process (GO:0016126)2.56009647
95response to pheromone (GO:0019236)2.55497067
96negative regulation of axon guidance (GO:1902668)2.54688697
97retina layer formation (GO:0010842)2.54599452
98thrombin receptor signaling pathway (GO:0070493)2.54560728
99isoprenoid biosynthetic process (GO:0008299)2.53817447
100mesenchymal cell differentiation (GO:0048762)2.53477118
101negative regulation of oligodendrocyte differentiation (GO:0048715)2.52630991
102regulation of endothelial cell differentiation (GO:0045601)2.52335028
103olfactory bulb development (GO:0021772)2.52327175
104cornea development in camera-type eye (GO:0061303)2.52208336
105DNA double-strand break processing (GO:0000729)2.51579769
106nucleotide transmembrane transport (GO:1901679)2.49328317
107positive regulation of synapse assembly (GO:0051965)2.48599124
108negative regulation of glial cell differentiation (GO:0045686)2.48421941
109hindbrain development (GO:0030902)2.48286861
110midbrain development (GO:0030901)2.46922364
111dentate gyrus development (GO:0021542)2.44767732
112photoreceptor cell maintenance (GO:0045494)2.43370861
113opioid receptor signaling pathway (GO:0038003)2.42640087
114extracellular regulation of signal transduction (GO:1900115)2.42632446
115extracellular negative regulation of signal transduction (GO:1900116)2.42632446
116positive regulation of protein homodimerization activity (GO:0090073)2.41131898
117regulation of male gonad development (GO:2000018)2.41003961
118regulation of hippo signaling (GO:0035330)2.40551574
119tonic smooth muscle contraction (GO:0014820)2.40435375
120dorsal/ventral pattern formation (GO:0009953)2.40333210
121spinal cord motor neuron differentiation (GO:0021522)2.40164826
122cell proliferation involved in metanephros development (GO:0072203)2.39903506
123regulation of cilium movement (GO:0003352)2.39650135
124microtubule depolymerization (GO:0007019)2.39466455
125positive regulation of chondrocyte differentiation (GO:0032332)2.39332651
126mesonephros development (GO:0001823)2.39081741
127negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.37716928
128heart valve formation (GO:0003188)2.37521388
129regulation of pigment cell differentiation (GO:0050932)2.36966231
130negative regulation of homotypic cell-cell adhesion (GO:0034111)2.36857943
131lateral sprouting from an epithelium (GO:0060601)2.35726758
132blood vessel maturation (GO:0001955)2.35588191
133lymphoid progenitor cell differentiation (GO:0002320)2.34914082
134adenosine metabolic process (GO:0046085)2.34846934
135chromatin remodeling at centromere (GO:0031055)2.34263330
136nephron tubule development (GO:0072080)2.34262586
137regulation of platelet aggregation (GO:0090330)2.34071871
138inner ear receptor cell differentiation (GO:0060113)2.33556884
139replication fork processing (GO:0031297)2.33446189
140positive regulation of gastrulation (GO:2000543)2.33407481
141eye photoreceptor cell differentiation (GO:0001754)2.32575604
142photoreceptor cell differentiation (GO:0046530)2.32575604
143protein K6-linked ubiquitination (GO:0085020)2.32484386
144glycerophospholipid catabolic process (GO:0046475)2.32286569
145response to redox state (GO:0051775)2.32263883
146positive regulation of protein kinase C signaling (GO:0090037)2.32043238
147nephron epithelium development (GO:0072009)2.31762166
148telencephalon development (GO:0021537)2.31370610
149positive regulation of uterine smooth muscle contraction (GO:0070474)2.31328209
150sympathetic nervous system development (GO:0048485)2.30835419
151sulfate transport (GO:0008272)2.30827469
152axon extension involved in axon guidance (GO:0048846)2.30485947
153neuron projection extension involved in neuron projection guidance (GO:1902284)2.30485947
154secondary metabolite biosynthetic process (GO:0044550)2.30117043
155regulation of penile erection (GO:0060405)2.29592949
156phasic smooth muscle contraction (GO:0014821)2.29196549
157superoxide metabolic process (GO:0006801)2.29147619
158regulation of astrocyte differentiation (GO:0048710)2.28974673
159positive regulation of cartilage development (GO:0061036)2.28707993
160cullin deneddylation (GO:0010388)2.28692281
161calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.28690933
162kinetochore organization (GO:0051383)2.28633301
163lens fiber cell development (GO:0070307)2.28351856
164forebrain neuron differentiation (GO:0021879)2.27802524
165thalamus development (GO:0021794)2.27552830
166positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.27128415
167cyclic nucleotide catabolic process (GO:0009214)2.26804282
168cranial nerve development (GO:0021545)2.26158570
169auditory receptor cell stereocilium organization (GO:0060088)2.26048787
170positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.25972535
171sulfate transmembrane transport (GO:1902358)2.25938200
172centriole assembly (GO:0098534)2.25631639
173positive regulation of cellular amine metabolic process (GO:0033240)2.25331452
174DNA integration (GO:0015074)2.25135474
175oligodendrocyte differentiation (GO:0048709)2.24563465
176short-term memory (GO:0007614)2.24450861
177cranial nerve structural organization (GO:0021604)2.24194812
178metanephric nephron tubule development (GO:0072234)2.20507041
179metanephric tubule development (GO:0072170)2.20507041
180activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.20478870
181left/right axis specification (GO:0070986)2.19286876
182renal tubule development (GO:0061326)2.19122249
183cell differentiation in spinal cord (GO:0021515)2.18959235
184regulation of activation of Janus kinase activity (GO:0010533)2.18287305
185mechanoreceptor differentiation (GO:0042490)2.18092356
186spinal cord association neuron differentiation (GO:0021527)2.17899467
187regulation of synapse assembly (GO:0051963)2.16845426

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.93796286
2EZH2_22144423_ChIP-Seq_EOC_Human3.17095088
3ZFP57_27257070_Chip-Seq_ESCs_Mouse2.82581639
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.61691303
5BMI1_23680149_ChIP-Seq_NPCS_Mouse2.58319286
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.50026432
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.49956870
8* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.33007095
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.30340221
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.28100913
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.27414322
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.22778449
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.17916542
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.13856707
15SUZ12_27294783_Chip-Seq_NPCs_Mouse2.12541301
16TAF15_26573619_Chip-Seq_HEK293_Human2.10908284
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.08452073
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.04382800
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03213450
20PCGF2_27294783_Chip-Seq_NPCs_Mouse2.03031753
21POU3F2_20337985_ChIP-ChIP_501MEL_Human1.97577977
22NFE2_27457419_Chip-Seq_LIVER_Mouse1.96861942
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.96670051
24IGF1R_20145208_ChIP-Seq_DFB_Human1.94660652
25ZNF274_21170338_ChIP-Seq_K562_Hela1.87113682
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.86683485
27P300_19829295_ChIP-Seq_ESCs_Human1.85107616
28NANOG_18555785_Chip-Seq_ESCs_Mouse1.84414679
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84095992
30EZH2_18974828_ChIP-Seq_MESCs_Mouse1.83854056
31RNF2_18974828_ChIP-Seq_MESCs_Mouse1.83854056
32VDR_22108803_ChIP-Seq_LS180_Human1.83649629
33EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.82861334
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.81010307
35TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.78515311
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.77779621
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.77186911
38RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.75062418
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.74066156
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.71820312
41E2F1_18555785_Chip-Seq_ESCs_Mouse1.70984390
42* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.70977095
43RNF2_27304074_Chip-Seq_NSC_Mouse1.70337138
44P53_22387025_ChIP-Seq_ESCs_Mouse1.69993945
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.66651917
46STAT3_18555785_Chip-Seq_ESCs_Mouse1.64772516
47EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.62429824
48EZH2_27294783_Chip-Seq_ESCs_Mouse1.62141918
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61619316
50CMYC_18555785_Chip-Seq_ESCs_Mouse1.59756611
51SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59707607
52* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59237934
53P300_18555785_Chip-Seq_ESCs_Mouse1.56697792
54CDX2_19796622_ChIP-Seq_MESCs_Mouse1.55847133
55RNF2_27304074_Chip-Seq_ESCs_Mouse1.55817323
56ELK1_19687146_ChIP-ChIP_HELA_Human1.54854351
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.54152536
58* NMYC_18555785_Chip-Seq_ESCs_Mouse1.52537274
59AR_21572438_ChIP-Seq_LNCaP_Human1.52419726
60SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52170815
61WT1_19549856_ChIP-ChIP_CCG9911_Human1.51282188
62CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.50807003
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.50674051
64NRF2_20460467_ChIP-Seq_MEFs_Mouse1.50674051
65SMAD3_21741376_ChIP-Seq_EPCs_Human1.50220763
66ER_23166858_ChIP-Seq_MCF-7_Human1.48528539
67RUNX1_27457419_Chip-Seq_LIVER_Mouse1.48460247
68SOX2_18555785_Chip-Seq_ESCs_Mouse1.46715334
69MTF2_20144788_ChIP-Seq_MESCs_Mouse1.46091468
70OCT4_18555785_Chip-Seq_ESCs_Mouse1.43744240
71KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.42881217
72FUS_26573619_Chip-Seq_HEK293_Human1.42544787
73ZFX_18555785_Chip-Seq_ESCs_Mouse1.41197236
74SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.41034663
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.40659333
76* SMAD4_21799915_ChIP-Seq_A2780_Human1.40548375
77KLF4_18555785_Chip-Seq_ESCs_Mouse1.39556823
78BCAT_22108803_ChIP-Seq_LS180_Human1.38232633
79POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37327225
80NR3C1_21868756_ChIP-Seq_MCF10A_Human1.36998190
81* TAL1_26923725_Chip-Seq_HPCs_Mouse1.36008043
82TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35950497
83PU1_27457419_Chip-Seq_LIVER_Mouse1.35524282
84MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35518620
85CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33576560
86SMAD_19615063_ChIP-ChIP_OVARY_Human1.33185692
87TP53_18474530_ChIP-ChIP_U2OS_Human1.32360169
88* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.31555583
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29929021
90SMAD1_18555785_Chip-Seq_ESCs_Mouse1.29711402
91CTCF_18555785_Chip-Seq_ESCs_Mouse1.29610951
92CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.28481485
93TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.27441522
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.27360151
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25779213
96* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25597013
97EWS_26573619_Chip-Seq_HEK293_Human1.25363453
98TCF4_22108803_ChIP-Seq_LS180_Human1.24395292
99CRX_20693478_ChIP-Seq_RETINA_Mouse1.23121342
100CJUN_26792858_Chip-Seq_BT549_Human1.23075827
101CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.22992320
102FOXM1_26456572_ChIP-Seq_MCF-7_Human1.21285418
103KDM2B_26808549_Chip-Seq_REH_Human1.20541163
104IRF1_19129219_ChIP-ChIP_H3396_Human1.20283955
105OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20221653
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19670088
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19670088
108RUNX2_22187159_ChIP-Seq_PCA_Human1.19399092
109SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19074587
110ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17710673
111SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.17214579
112* SOX9_26525672_Chip-Seq_HEART_Mouse1.16925681
113* JUN_21703547_ChIP-Seq_K562_Human1.16127481
114E2F4_17652178_ChIP-ChIP_JURKAT_Human1.15850958
115TP53_16413492_ChIP-PET_HCT116_Human1.15396410
116* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15109651
117SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14980084
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14524027
119CBP_20019798_ChIP-Seq_JUKART_Human1.14524027
120TBX3_20139965_ChIP-Seq_MESCs_Mouse1.13400216
121TBX3_20139965_ChIP-Seq_ESCs_Mouse1.12878508
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.12300517
123ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11917858
124* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.11209187
125P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10891369
126SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.10881615
127* SOX2_21211035_ChIP-Seq_LN229_Gbm1.09767806
128PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09501674
129AR_25329375_ChIP-Seq_VCAP_Human1.09180054
130* STAT3_23295773_ChIP-Seq_U87_Human1.09080262
131* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09022470
132SOX2_16153702_ChIP-ChIP_HESCs_Human1.08547788
133* TCF4_23295773_ChIP-Seq_U87_Human1.07121181
134DROSHA_22980978_ChIP-Seq_HELA_Human1.07110264
135ARNT_22903824_ChIP-Seq_MCF-7_Human1.04790752
136TRIM28_21343339_ChIP-Seq_HEK293_Human1.03704893
137FLI1_21867929_ChIP-Seq_TH2_Mouse1.02734583
138YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02090627
139FOXM1_23109430_ChIP-Seq_U2OS_Human1.01290718
140TBL1_22424771_ChIP-Seq_293T_Human1.00862031

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.36785200
2MP0001188_hyperpigmentation4.09723523
3MP0003136_yellow_coat_color3.84968477
4MP0003880_abnormal_central_pattern3.16665441
5MP0004381_abnormal_hair_follicle2.92478812
6MP0005409_darkened_coat_color2.78225808
7MP0006292_abnormal_olfactory_placode2.74556468
8MP0002102_abnormal_ear_morphology2.73351090
9MP0005248_abnormal_Harderian_gland2.51445475
10MP0010030_abnormal_orbit_morphology2.42703118
11MP0005451_abnormal_body_composition2.30209097
12MP0005645_abnormal_hypothalamus_physiol2.24312135
13MP0002277_abnormal_respiratory_mucosa2.21704101
14MP0003941_abnormal_skin_development2.20692038
15MP0010368_abnormal_lymphatic_system2.16592179
16MP0005171_absent_coat_pigmentation2.15781327
17MP0004742_abnormal_vestibular_system2.11809138
18MP0001293_anophthalmia2.11077450
19MP0001486_abnormal_startle_reflex2.07155468
20MP0001879_abnormal_lymphatic_vessel1.96061016
21MP0000383_abnormal_hair_follicle1.95611957
22MP0000026_abnormal_inner_ear1.93934741
23MP0005423_abnormal_somatic_nervous1.88863817
24MP0004272_abnormal_basement_membrane1.82978353
25MP0010386_abnormal_urinary_bladder1.80023658
26MP0006276_abnormal_autonomic_nervous1.77462522
27MP0008789_abnormal_olfactory_epithelium1.75793846
28MP0009053_abnormal_anal_canal1.74921475
29MP0002653_abnormal_ependyma_morphology1.74110239
30MP0001958_emphysema1.73898471
31MP0002138_abnormal_hepatobiliary_system1.69732915
32MP0002282_abnormal_trachea_morphology1.67240046
33MP0002234_abnormal_pharynx_morphology1.62877549
34MP0001963_abnormal_hearing_physiology1.59631030
35MP0004142_abnormal_muscle_tone1.59574806
36MP0000778_abnormal_nervous_system1.59006607
37MP0009379_abnormal_foot_pigmentation1.51912308
38MP0000579_abnormal_nail_morphology1.51806386
39MP0001986_abnormal_taste_sensitivity1.46703369
40MP0005187_abnormal_penis_morphology1.45519426
41MP0005379_endocrine/exocrine_gland_phen1.44701192
42MP0000569_abnormal_digit_pigmentation1.44165677
43MP0005084_abnormal_gallbladder_morpholo1.43790770
44MP0008260_abnormal_autophagy1.43775580
45MP0000428_abnormal_craniofacial_morphol1.42565034
46MP0000762_abnormal_tongue_morphology1.42495908
47MP0003724_increased_susceptibility_to1.41172048
48MP0003938_abnormal_ear_development1.41006542
49MP0002938_white_spotting1.40341026
50MP0001485_abnormal_pinna_reflex1.40184505
51MP0001346_abnormal_lacrimal_gland1.39772285
52MP0000015_abnormal_ear_pigmentation1.39628031
53MP0005646_abnormal_pituitary_gland1.37401803
54MP0005174_abnormal_tail_pigmentation1.32782846
55MP0005377_hearing/vestibular/ear_phenot1.32676772
56MP0003878_abnormal_ear_physiology1.32676772
57MP0001529_abnormal_vocalization1.32293028
58MP0002638_abnormal_pupillary_reflex1.31041804
59MP0009250_abnormal_appendicular_skeleto1.30682079
60MP0002735_abnormal_chemical_nociception1.30095131
61MP0000534_abnormal_ureter_morphology1.29276756
62MP0005391_vision/eye_phenotype1.27765016
63MP0009697_abnormal_copulation1.26870702
64MP0002233_abnormal_nose_morphology1.26270580
65MP0002876_abnormal_thyroid_physiology1.24770883
66MP0003011_delayed_dark_adaptation1.24084131
67MP0001286_abnormal_eye_development1.23556976
68MP0004019_abnormal_vitamin_homeostasis1.23321554
69MP0001968_abnormal_touch/_nociception1.21798647
70MP0001299_abnormal_eye_distance/1.21190535
71MP0002249_abnormal_larynx_morphology1.20675085
72MP0004043_abnormal_pH_regulation1.19782804
73MP0005195_abnormal_posterior_eye1.19547705
74MP0002067_abnormal_sensory_capabilities1.18553960
75MP0001905_abnormal_dopamine_level1.18374546
76MP0002736_abnormal_nociception_after1.18241948
77MP0000049_abnormal_middle_ear1.17848791
78MP0002092_abnormal_eye_morphology1.17673604
79MP0001324_abnormal_eye_pigmentation1.17260958
80MP0009745_abnormal_behavioral_response1.16973777
81MP0005551_abnormal_eye_electrophysiolog1.16963970
82MP0000537_abnormal_urethra_morphology1.16253715
83MP0000631_abnormal_neuroendocrine_gland1.15905860
84MP0005394_taste/olfaction_phenotype1.13473048
85MP0005499_abnormal_olfactory_system1.13473048
86MP0009046_muscle_twitch1.12655426
87MP0004133_heterotaxia1.09918726
88MP0002697_abnormal_eye_size1.08318796
89MP0005595_abnormal_vascular_smooth1.07685297
90MP0005257_abnormal_intraocular_pressure1.07286133
91MP0002752_abnormal_somatic_nervous1.03964545
92MP0006054_spinal_hemorrhage1.03859064
93MP0009384_cardiac_valve_regurgitation1.03045425
94MP0002572_abnormal_emotion/affect_behav1.02871566
95MP0002272_abnormal_nervous_system1.02819841
96MP0002163_abnormal_gland_morphology1.01110351
97MP0002557_abnormal_social/conspecific_i1.00791079
98MP0010678_abnormal_skin_adnexa1.00757340
99MP0005408_hypopigmentation1.00123398
100MP0000538_abnormal_urinary_bladder0.98417261
101MP0005464_abnormal_platelet_physiology0.97644402
102MP0000920_abnormal_myelination0.96595357
103MP0000372_irregular_coat_pigmentation0.95919135
104MP0003935_abnormal_craniofacial_develop0.95371394
105MP0008004_abnormal_stomach_pH0.94870493
106MP0001440_abnormal_grooming_behavior0.94264455
107MP0002098_abnormal_vibrissa_morphology0.92381013
108MP0005503_abnormal_tendon_morphology0.92008252
109MP0001501_abnormal_sleep_pattern0.91868367
110MP0000613_abnormal_salivary_gland0.91722226
111MP0000462_abnormal_digestive_system0.91459582
112MP0002734_abnormal_mechanical_nocicepti0.88182274
113MP0003385_abnormal_body_wall0.87749044
114MP0003718_maternal_effect0.87653795
115MP0002064_seizures0.86508316
116MP0001177_atelectasis0.85662688
117MP0002295_abnormal_pulmonary_circulatio0.84879649
118MP0004885_abnormal_endolymph0.82422451
119MP0003879_abnormal_hair_cell0.82191762
120MP0008438_abnormal_cutaneous_collagen0.81573847
121MP0003937_abnormal_limbs/digits/tail_de0.81208477
122MP0002928_abnormal_bile_duct0.81099341
123MP0003942_abnormal_urinary_system0.80502604
124MP0008932_abnormal_embryonic_tissue0.79977156
125MP0009780_abnormal_chondrocyte_physiolo0.78617704
126MP0004215_abnormal_myocardial_fiber0.78152204
127MP0000230_abnormal_systemic_arterial0.77927801
128MP0003195_calcinosis0.77778922
129MP0002184_abnormal_innervation0.77240619
130MP0006072_abnormal_retinal_apoptosis0.77186247
131MP0004134_abnormal_chest_morphology0.77140697
132MP0002177_abnormal_outer_ear0.77076251
133MP0000465_gastrointestinal_hemorrhage0.77015710
134MP0002095_abnormal_skin_pigmentation0.76952856
135MP0002751_abnormal_autonomic_nervous0.75889309
136MP0003787_abnormal_imprinting0.75451789
137MP0003119_abnormal_digestive_system0.75196553
138MP0003861_abnormal_nervous_system0.74689834
139MP0010094_abnormal_chromosome_stability0.74598016
140MP0001984_abnormal_olfaction0.74505564
141MP0000427_abnormal_hair_cycle0.73575313
142MP0005167_abnormal_blood-brain_barrier0.73212197
143MP0001765_abnormal_ion_homeostasis0.72320210
144MP0005197_abnormal_uvea_morphology0.71259324
145MP0003950_abnormal_plasma_membrane0.70975419
146MP0003122_maternal_imprinting0.70971796
147MP0003635_abnormal_synaptic_transmissio0.70718706
148MP0001664_abnormal_digestion0.70177256
149MP0005508_abnormal_skeleton_morphology0.69015289
150MP0005253_abnormal_eye_physiology0.69003414
151MP0000647_abnormal_sebaceous_gland0.67959420
152MP0003755_abnormal_palate_morphology0.67262377
153MP0001186_pigmentation_phenotype0.66905648
154MP0005075_abnormal_melanosome_morpholog0.66813180
155MP0002116_abnormal_craniofacial_bone0.66713058
156MP0005623_abnormal_meninges_morphology0.66466858
157MP0002063_abnormal_learning/memory/cond0.64690938

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.31285586
2True hermaphroditism (HP:0010459)4.05981368
3Parakeratosis (HP:0001036)3.93003999
4Chromsome breakage (HP:0040012)3.60637371
5Congenital sensorineural hearing impairment (HP:0008527)3.35660416
6Metabolic alkalosis (HP:0200114)3.32276617
7Abnormality of midbrain morphology (HP:0002418)3.28854268
8Molar tooth sign on MRI (HP:0002419)3.28854268
9Duplicated collecting system (HP:0000081)3.25633536
10Menorrhagia (HP:0000132)3.23380974
11Septo-optic dysplasia (HP:0100842)3.13222342
12Increased mean platelet volume (HP:0011877)3.10920310
13Esophageal atresia (HP:0002032)3.09423106
14Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.09044545
15Abnormal ciliary motility (HP:0012262)3.08252308
16Dynein arm defect of respiratory motile cilia (HP:0012255)3.07059378
17Absent/shortened dynein arms (HP:0200106)3.07059378
18Pancreatic fibrosis (HP:0100732)3.02842413
19Febrile seizures (HP:0002373)2.92658669
20Abnormality of the renal collecting system (HP:0004742)2.90118669
21Osteomalacia (HP:0002749)2.85119105
22Short 4th metacarpal (HP:0010044)2.84378434
23Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.84378434
24Upper limb muscle weakness (HP:0003484)2.81326044
25Hypomagnesemia (HP:0002917)2.79868538
26Abnormality of the diencephalon (HP:0010662)2.75555883
27Abnormal auditory evoked potentials (HP:0006958)2.74692504
28Colon cancer (HP:0003003)2.71831616
29Pancreatic cysts (HP:0001737)2.71125695
30Hypothermia (HP:0002045)2.66104793
31Prostate neoplasm (HP:0100787)2.65277533
32Gastrointestinal atresia (HP:0002589)2.63881759
33Duplication of thumb phalanx (HP:0009942)2.63427924
34Aplasia cutis congenita (HP:0001057)2.61364176
35Abnormality of incisor morphology (HP:0011063)2.60635229
36Abnormal platelet volume (HP:0011876)2.53967282
37Aplasia/Hypoplasia of the tongue (HP:0010295)2.53951286
38Abnormality of the renal medulla (HP:0100957)2.52763208
39Abnormal respiratory motile cilium physiology (HP:0012261)2.51297735
40White forelock (HP:0002211)2.50583283
41Conical tooth (HP:0000698)2.50034790
42Abnormality of the proximal phalanges of the hand (HP:0009834)2.49983722
43Hypophosphatemic rickets (HP:0004912)2.48211858
44Median cleft lip (HP:0000161)2.44298599
45Hyperactive renin-angiotensin system (HP:0000841)2.41509187
46Patchy hypopigmentation of hair (HP:0011365)2.41201547
47Large earlobe (HP:0009748)2.39930518
48Increased circulating renin level (HP:0000848)2.37921943
49Abnormality of the labia minora (HP:0012880)2.36116623
50Abnormal respiratory motile cilium morphology (HP:0005938)2.35932245
51Abnormal respiratory epithelium morphology (HP:0012253)2.35932245
52Abnormality of the fovea (HP:0000493)2.34068712
53Fibular hypoplasia (HP:0003038)2.33733285
54Postaxial hand polydactyly (HP:0001162)2.30061249
55Postaxial foot polydactyly (HP:0001830)2.29647185
56Aplasia/Hypoplasia of the fibula (HP:0006492)2.27650272
57Abnormality of chloride homeostasis (HP:0011422)2.26506821
58Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.24790052
59Vertebral hypoplasia (HP:0008417)2.24652503
60Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.24652503
61Preaxial hand polydactyly (HP:0001177)2.24545646
62Absent septum pellucidum (HP:0001331)2.23294352
63Hypoplastic pelvis (HP:0008839)2.22933523
64Abnormality of the 4th metacarpal (HP:0010012)2.22744403
65Choroideremia (HP:0001139)2.22552732
66Abnormality of the antihelix (HP:0009738)2.21914585
67Hemiparesis (HP:0001269)2.21599390
68Hypokalemic alkalosis (HP:0001949)2.20194002
69Decreased central vision (HP:0007663)2.17679160
70Tubulointerstitial nephritis (HP:0001970)2.17351032
71Anomalous pulmonary venous return (HP:0010772)2.16848532
72Optic nerve hypoplasia (HP:0000609)2.15896026
73Hyperaldosteronism (HP:0000859)2.15769826
74Nephronophthisis (HP:0000090)2.13864778
75Sclerocornea (HP:0000647)2.12291280
76Polyuria (HP:0000103)2.10135410
77Hypoplastic iliac wings (HP:0002866)2.09281171
78Conjunctival telangiectasia (HP:0000524)2.08983239
79Abnormality of renin-angiotensin system (HP:0000847)2.07453094
80Neonatal short-limb short stature (HP:0008921)2.05692418
81Abnormality of the septum pellucidum (HP:0007375)2.05021862
82Thyroid-stimulating hormone excess (HP:0002925)2.04182458
83Prolonged bleeding time (HP:0003010)2.04150298
84Congenital primary aphakia (HP:0007707)2.03844992
85Tetany (HP:0001281)2.01691636
86Congenital hepatic fibrosis (HP:0002612)2.00975819
87Overfolded helix (HP:0000396)2.00109023
88Nasolacrimal duct obstruction (HP:0000579)1.98999157
89Xerostomia (HP:0000217)1.98102889
90Hemivertebrae (HP:0002937)1.97951270
91Renal cortical cysts (HP:0000803)1.97819588
92Abnormality of the renal cortex (HP:0011035)1.96989362
93Occipital encephalocele (HP:0002085)1.96694344
94Gait imbalance (HP:0002141)1.96177772
95Volvulus (HP:0002580)1.95451141
96Abnormality of magnesium homeostasis (HP:0004921)1.94087879
97Aplasia/Hypoplasia of the fovea (HP:0008060)1.93946765
98Hypoplasia of the fovea (HP:0007750)1.93946765
99Cystic liver disease (HP:0006706)1.93233132
100Hypoplasia of the iris (HP:0007676)1.92287186
101Metaphyseal irregularity (HP:0003025)1.92186389
102Abnormality of molar (HP:0011077)1.91491199
103Abnormality of molar morphology (HP:0011070)1.91491199
104Short tibia (HP:0005736)1.90590469
105Aplasia/Hypoplasia of the tibia (HP:0005772)1.90234071
106Cupped ear (HP:0000378)1.89807098
107Decreased lacrimation (HP:0000633)1.89341334
108Alacrima (HP:0000522)1.89166710
109Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.88970706
110Aplasia of the musculature (HP:0100854)1.88016550
111Abnormality of renal excretion (HP:0011036)1.87173204
112Nephrogenic diabetes insipidus (HP:0009806)1.86744411
113Atelectasis (HP:0100750)1.85890596
114Neoplasm of the oral cavity (HP:0100649)1.85590921
115Partial duplication of thumb phalanx (HP:0009944)1.84920598
116Abnormality of the lacrimal duct (HP:0011481)1.84144906
117Male pseudohermaphroditism (HP:0000037)1.84093204
118Congenital stationary night blindness (HP:0007642)1.83208206
119Abnormality of renal resorption (HP:0011038)1.83198124
120Abnormality of the pulmonary veins (HP:0011718)1.82527823
121Abnormal drinking behavior (HP:0030082)1.81645208
122Polydipsia (HP:0001959)1.81645208
123Focal motor seizures (HP:0011153)1.80089988
124Abnormality of the preputium (HP:0100587)1.80088405
125Anencephaly (HP:0002323)1.78801505
126Drooling (HP:0002307)1.78763886
127Coronal craniosynostosis (HP:0004440)1.78667105
128Chronic hepatic failure (HP:0100626)1.78159202
129Abnormal urine output (HP:0012590)1.77519412
130Abnormality of secondary sexual hair (HP:0009888)1.77115162
131Abnormality of the axillary hair (HP:0100134)1.77115162
132Medial flaring of the eyebrow (HP:0010747)1.76758325
133Abnormality of the middle phalanges of the toes (HP:0010183)1.76587138
134Papillary thyroid carcinoma (HP:0002895)1.76036413
135Aplasia/hypoplasia of the uterus (HP:0008684)1.75978588
136Renal agenesis (HP:0000104)1.75967661
137Fair hair (HP:0002286)1.75926531
138Congenital, generalized hypertrichosis (HP:0004540)1.74505103
139Hypopigmentation of the fundus (HP:0007894)1.74058233
140Lissencephaly (HP:0001339)1.73779363
141Keratoconus (HP:0000563)1.73531017
142Increased corneal curvature (HP:0100692)1.73531017
143Mixed hearing impairment (HP:0000410)1.72910462
144Type II lissencephaly (HP:0007260)1.72819136
145Aplasia/Hypoplasia of the uvula (HP:0010293)1.72082010
146Genital tract atresia (HP:0001827)1.72074089
147Adrenal hypoplasia (HP:0000835)1.71893426
148Stage 5 chronic kidney disease (HP:0003774)1.70675657
149Recurrent corneal erosions (HP:0000495)1.70516394
150Intestinal atresia (HP:0011100)1.70453284
151Narrow forehead (HP:0000341)1.70342953
152Abnormality of the nasolacrimal system (HP:0000614)1.69910104
153Recurrent cutaneous fungal infections (HP:0011370)1.69679262
154Chronic mucocutaneous candidiasis (HP:0002728)1.69679262
155Glioma (HP:0009733)1.69343790
156Aplasia involving bones of the upper limbs (HP:0009823)1.69222079
157Aplasia of the phalanges of the hand (HP:0009802)1.69222079
158Aplasia involving bones of the extremities (HP:0009825)1.69222079
159Facial hemangioma (HP:0000329)1.69176974
160Submucous cleft hard palate (HP:0000176)1.69138175
161Retinal dysplasia (HP:0007973)1.69058950
162Hyperglycinemia (HP:0002154)1.68540659
163Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.68011117
164Maternal diabetes (HP:0009800)1.67760035
165Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67618046
166Myelomeningocele (HP:0002475)1.67491119
167Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.66842231
168Abnormality of the phalanges of the 2nd finger (HP:0009541)1.66690379
169Medulloblastoma (HP:0002885)1.66347826
170Vaginal atresia (HP:0000148)1.65890237
171Abnormality of DNA repair (HP:0003254)1.63404615
172Abnormality of the dental root (HP:0006486)1.63337818
173Taurodontia (HP:0000679)1.63337818
174Abnormality of permanent molar morphology (HP:0011071)1.63337818

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.97919996
2WEE13.13831653
3OXSR12.75001206
4TXK2.14100999
5MAP4K22.11745841
6STK392.09623779
7TSSK62.08829644
8EIF2AK22.05857507
9INSRR2.04070999
10GRK72.01061734
11TNIK2.00303522
12STK162.00118396
13PKN11.95437374
14ADRBK21.92905348
15TGFBR11.90857703
16WNK31.90784488
17BMPR1B1.90057160
18BRSK21.74116278
19IRAK31.73818207
20ZAK1.71246677
21WNK41.64758359
22GRK11.64338000
23IRAK41.63558472
24MAP2K71.63362522
25MAPK151.63005451
26PLK31.54398404
27TRIM281.53898656
28MAP3K141.53753825
29YES11.53021889
30MST41.50959339
31MKNK21.50605872
32PLK41.49356339
33NEK91.47680469
34NEK61.42337917
35PBK1.41093987
36BMPR21.40763203
37PTK2B1.37077775
38CCNB11.36616330
39IRAK11.36491267
40MUSK1.31480920
41IRAK21.31332225
42EIF2AK11.30497322
43MAPK131.28240823
44SIK31.26240919
45MYLK1.22356610
46CDK31.18681701
47MAP3K91.18669811
48TLK11.15673639
49NTRK31.15512280
50BCR1.15475719
51AKT31.09383257
52PIK3CG1.08974802
53BRD41.08034581
54BUB11.07090925
55CLK11.06828851
56DDR21.03132453
57BLK1.01796016
58NUAK11.00400143
59PRKCE0.98967276
60TAF10.97569436
61EPHA40.95138562
62PAK60.92845049
63VRK20.92203034
64PNCK0.91209923
65ERBB30.91199317
66SGK2230.90948358
67SGK4940.90948358
68EPHB20.90588442
69PRPF4B0.88596547
70CSNK1G20.86388805
71VRK10.84141112
72WNK10.82883200
73PIK3CA0.82471098
74ROCK10.82425567
75CDC70.82381583
76PRKD30.80722895
77CDK80.80715989
78CSNK1G30.79421514
79MKNK10.78867322
80DYRK20.78715056
81STK38L0.77813110
82STK30.77117462
83FES0.75397101
84NLK0.75212249
85DYRK30.74754956
86NEK10.74605493
87MET0.73609718
88CAMK2B0.73526707
89BMX0.73484196
90EPHA30.73312996
91TEC0.72876790
92FER0.70138870
93PLK10.69852174
94SGK20.69484247
95EPHB10.69454575
96FGR0.67855556
97ERBB20.67412136
98KSR10.67275555
99PAK20.66080797
100ROCK20.65150455
101GRK50.63727872
102CAMK2A0.62014306
103TIE10.61282940
104PLK20.59566522
105MARK10.59250890
106PINK10.59071094
107MAPKAPK30.58961387
108NTRK20.58669948
109AURKB0.57687790
110CAMK1G0.57018211
111MAPKAPK50.55841502
112RIPK40.55330310
113MAP3K40.54137888
114ADRBK10.53821369
115FRK0.53508853
116LATS10.52176311
117SRPK10.51419609
118IKBKE0.51137417
119DYRK1A0.50821335
120SGK10.50403720
121PRKG10.49965631
122CAMK2D0.48749541
123MAPK70.48730979
124TRPM70.48697133
125PRKCG0.48408687
126SIK20.48058113
127LYN0.47578740
128MINK10.47551798
129MAP3K120.47222908
130PRKCQ0.47201477
131MST1R0.46269290
132UHMK10.45646827
133IKBKB0.44975874
134ERBB40.43628241
135NTRK10.43587322
136PAK30.42114762
137MAP3K100.41755780
138CAMK10.41470385
139GSK3A0.40987760
140TAOK30.40160160
141CSNK1A1L0.40046676
142RPS6KA50.38920032
143EIF2AK30.38388678
144PRKACA0.38293364
145PRKD20.38080960
146FGFR20.37216081
147BRSK10.36501539
148CDK190.35956761
149CDK90.35897111
150CAMK2G0.35802179
151MAP3K130.35623580
152ATM0.35500630
153NEK20.34596572
154LIMK10.34345178
155AURKA0.34027761
156CSNK1G10.31985374

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.46379943
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.44026240
3Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.39200841
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.19433095
5Nitrogen metabolism_Homo sapiens_hsa009102.08793303
6Sphingolipid metabolism_Homo sapiens_hsa006002.07444801
7Fanconi anemia pathway_Homo sapiens_hsa034602.01258439
8Steroid biosynthesis_Homo sapiens_hsa001001.98288390
9Ether lipid metabolism_Homo sapiens_hsa005651.97319995
10Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.96059088
11Mismatch repair_Homo sapiens_hsa034301.93287616
12Phototransduction_Homo sapiens_hsa047441.91337165
13Oxidative phosphorylation_Homo sapiens_hsa001901.89146682
14TGF-beta signaling pathway_Homo sapiens_hsa043501.82091030
15Hippo signaling pathway_Homo sapiens_hsa043901.82018895
16Propanoate metabolism_Homo sapiens_hsa006401.78173241
17Collecting duct acid secretion_Homo sapiens_hsa049661.75765333
18Arachidonic acid metabolism_Homo sapiens_hsa005901.75627923
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.72009900
20Serotonergic synapse_Homo sapiens_hsa047261.68180341
21Taste transduction_Homo sapiens_hsa047421.66230526
22Rheumatoid arthritis_Homo sapiens_hsa053231.63338835
23Vitamin digestion and absorption_Homo sapiens_hsa049771.61588527
24Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.55635619
25Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.54873151
26Autoimmune thyroid disease_Homo sapiens_hsa053201.53920038
27Cell cycle_Homo sapiens_hsa041101.50159597
28Graft-versus-host disease_Homo sapiens_hsa053321.48056062
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.44246746
30Morphine addiction_Homo sapiens_hsa050321.42471435
31Fatty acid elongation_Homo sapiens_hsa000621.42146654
32Linoleic acid metabolism_Homo sapiens_hsa005911.37143485
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35586604
34Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.35448602
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.35116379
36Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.34596652
37Nucleotide excision repair_Homo sapiens_hsa034201.30280221
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27844582
39Basal cell carcinoma_Homo sapiens_hsa052171.27687044
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27490130
41Axon guidance_Homo sapiens_hsa043601.27385783
42Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.25498123
43Other glycan degradation_Homo sapiens_hsa005111.24290912
44Hematopoietic cell lineage_Homo sapiens_hsa046401.21392597
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.19707709
46One carbon pool by folate_Homo sapiens_hsa006701.19622282
47Gap junction_Homo sapiens_hsa045401.19462819
48Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.18166772
49Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.17261133
50Non-homologous end-joining_Homo sapiens_hsa034501.16594618
51Adherens junction_Homo sapiens_hsa045201.10168792
52Steroid hormone biosynthesis_Homo sapiens_hsa001401.09249831
53Hedgehog signaling pathway_Homo sapiens_hsa043401.08993612
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08091157
55Histidine metabolism_Homo sapiens_hsa003401.07812696
56Glutathione metabolism_Homo sapiens_hsa004801.05926453
57Intestinal immune network for IgA production_Homo sapiens_hsa046721.04435965
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03422642
59Alzheimers disease_Homo sapiens_hsa050101.02795953
60Homologous recombination_Homo sapiens_hsa034401.00673313
61Allograft rejection_Homo sapiens_hsa053300.98837530
62Glutamatergic synapse_Homo sapiens_hsa047240.98170649
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.97611585
64Asthma_Homo sapiens_hsa053100.96725763
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.96401245
66Maturity onset diabetes of the young_Homo sapiens_hsa049500.95928981
67NF-kappa B signaling pathway_Homo sapiens_hsa040640.93895537
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.93429558
69Platelet activation_Homo sapiens_hsa046110.93262226
70Tight junction_Homo sapiens_hsa045300.92773844
71Protein export_Homo sapiens_hsa030600.92244432
72DNA replication_Homo sapiens_hsa030300.91064201
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.91039912
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.90870350
75Ovarian steroidogenesis_Homo sapiens_hsa049130.88405796
76Parkinsons disease_Homo sapiens_hsa050120.86933334
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.85026567
78p53 signaling pathway_Homo sapiens_hsa041150.83563395
79Protein digestion and absorption_Homo sapiens_hsa049740.76983548
80Huntingtons disease_Homo sapiens_hsa050160.76669198
81Calcium signaling pathway_Homo sapiens_hsa040200.76388260
82GABAergic synapse_Homo sapiens_hsa047270.76196181
83Wnt signaling pathway_Homo sapiens_hsa043100.74603477
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74285272
85beta-Alanine metabolism_Homo sapiens_hsa004100.74284912
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.73671816
87Malaria_Homo sapiens_hsa051440.73469949
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72814584
89Base excision repair_Homo sapiens_hsa034100.72409439
90Oocyte meiosis_Homo sapiens_hsa041140.72029277
91Phagosome_Homo sapiens_hsa041450.70720458
92Cocaine addiction_Homo sapiens_hsa050300.70324925
93Focal adhesion_Homo sapiens_hsa045100.69665338
94Sulfur relay system_Homo sapiens_hsa041220.69617166
95Basal transcription factors_Homo sapiens_hsa030220.69234223
96Mineral absorption_Homo sapiens_hsa049780.67391114
97Sulfur metabolism_Homo sapiens_hsa009200.66952206
98Olfactory transduction_Homo sapiens_hsa047400.66423296
99Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65571341
100Salivary secretion_Homo sapiens_hsa049700.65470258
101Pyruvate metabolism_Homo sapiens_hsa006200.64614765
102Primary immunodeficiency_Homo sapiens_hsa053400.63282260
103Pathways in cancer_Homo sapiens_hsa052000.63222517
104Long-term depression_Homo sapiens_hsa047300.62969967
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.62934921
106Circadian entrainment_Homo sapiens_hsa047130.61436579
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61233547
108ECM-receptor interaction_Homo sapiens_hsa045120.61198638
109Folate biosynthesis_Homo sapiens_hsa007900.60382019
110Purine metabolism_Homo sapiens_hsa002300.59456684
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.59348868
112Pyrimidine metabolism_Homo sapiens_hsa002400.59019739
113Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58693295
114Ras signaling pathway_Homo sapiens_hsa040140.58280782
115Renin secretion_Homo sapiens_hsa049240.57537434
116Peroxisome_Homo sapiens_hsa041460.57291424
117Retinol metabolism_Homo sapiens_hsa008300.56989262
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56318714
119Notch signaling pathway_Homo sapiens_hsa043300.56194801
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.56053636
121Chemical carcinogenesis_Homo sapiens_hsa052040.54009588
122Melanoma_Homo sapiens_hsa052180.53913080
123Spliceosome_Homo sapiens_hsa030400.53027033
124Alcoholism_Homo sapiens_hsa050340.53007256
125Regulation of autophagy_Homo sapiens_hsa041400.52790649
126MicroRNAs in cancer_Homo sapiens_hsa052060.52591718
127Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.51802800
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51718165
129Melanogenesis_Homo sapiens_hsa049160.49750043
130Circadian rhythm_Homo sapiens_hsa047100.49284653
131Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49046866
132Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48772924
133Tyrosine metabolism_Homo sapiens_hsa003500.48648116
134cAMP signaling pathway_Homo sapiens_hsa040240.48385708
135RNA polymerase_Homo sapiens_hsa030200.48214233
136Amphetamine addiction_Homo sapiens_hsa050310.47905368
137African trypanosomiasis_Homo sapiens_hsa051430.47161238
138Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.46210576
139Rap1 signaling pathway_Homo sapiens_hsa040150.45857058
140Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45827455
141Vibrio cholerae infection_Homo sapiens_hsa051100.45678820
142Tryptophan metabolism_Homo sapiens_hsa003800.45452876
143Arginine and proline metabolism_Homo sapiens_hsa003300.45327494
144Selenocompound metabolism_Homo sapiens_hsa004500.44196687
145Cholinergic synapse_Homo sapiens_hsa047250.42618007
146Butanoate metabolism_Homo sapiens_hsa006500.42514234
147Dilated cardiomyopathy_Homo sapiens_hsa054140.42425809
148Chemokine signaling pathway_Homo sapiens_hsa040620.42307133
149Metabolic pathways_Homo sapiens_hsa011000.42065529
150NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41898724
151Measles_Homo sapiens_hsa051620.41313832
152Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39849712
153ErbB signaling pathway_Homo sapiens_hsa040120.39543530
154Choline metabolism in cancer_Homo sapiens_hsa052310.38025456
155ABC transporters_Homo sapiens_hsa020100.37949883
156Vascular smooth muscle contraction_Homo sapiens_hsa042700.37486297
157Type I diabetes mellitus_Homo sapiens_hsa049400.36436482
158Glycosaminoglycan degradation_Homo sapiens_hsa005310.34890613
159Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34360008
160Toll-like receptor signaling pathway_Homo sapiens_hsa046200.33109665

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