VASH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)5.69735357
2pyrimidine nucleobase catabolic process (GO:0006208)4.72587410
3locomotory exploration behavior (GO:0035641)4.66948357
4synaptic vesicle maturation (GO:0016188)4.63484182
5dendritic spine morphogenesis (GO:0060997)4.54866471
6cell migration in hindbrain (GO:0021535)4.51451769
7regulation of short-term neuronal synaptic plasticity (GO:0048172)4.33751346
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.32659152
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.20258777
10establishment of nucleus localization (GO:0040023)4.19655424
11regulation of synapse structural plasticity (GO:0051823)4.18451544
12vocalization behavior (GO:0071625)4.11827887
13dendrite morphogenesis (GO:0048813)4.08640975
14positive regulation of synapse maturation (GO:0090129)4.07414121
15axonal fasciculation (GO:0007413)4.05359952
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.95888311
17neuron recognition (GO:0008038)3.85865257
18central nervous system projection neuron axonogenesis (GO:0021952)3.84875068
19adenosine receptor signaling pathway (GO:0001973)3.83679402
20protein localization to synapse (GO:0035418)3.82144654
21cell communication by electrical coupling (GO:0010644)3.79272259
22neuron cell-cell adhesion (GO:0007158)3.76779679
23nucleobase catabolic process (GO:0046113)3.72692579
24regulation of glutamate receptor signaling pathway (GO:1900449)3.71440194
25exploration behavior (GO:0035640)3.66502111
26glutamate secretion (GO:0014047)3.46639902
27mitochondrion transport along microtubule (GO:0047497)3.44565305
28establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.44565305
29cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.42452212
30synaptic vesicle exocytosis (GO:0016079)3.40093281
31regulation of synaptic vesicle exocytosis (GO:2000300)3.37410324
32synaptic vesicle docking involved in exocytosis (GO:0016081)3.31341145
33axon extension (GO:0048675)3.30957379
34cell-cell junction maintenance (GO:0045217)3.28205555
35cerebellar Purkinje cell layer development (GO:0021680)3.26984836
36establishment of mitochondrion localization (GO:0051654)3.26703603
37positive regulation of axon extension (GO:0045773)3.24606293
38clathrin coat assembly (GO:0048268)3.20468171
39plasma membrane repair (GO:0001778)3.16017559
40activation of protein kinase A activity (GO:0034199)3.15972638
41regulation of synapse maturation (GO:0090128)3.14500505
42proline transport (GO:0015824)3.12575649
43neurotransmitter-gated ion channel clustering (GO:0072578)3.07844181
44gonadal mesoderm development (GO:0007506)3.07347633
45negative regulation of microtubule polymerization (GO:0031115)3.05768772
46cerebellar granule cell differentiation (GO:0021707)3.04002382
47postsynaptic membrane organization (GO:0001941)3.03928538
48endothelium development (GO:0003158)3.03102985
49sodium ion export (GO:0071436)3.01735420
50regulation of dendritic spine morphogenesis (GO:0061001)3.00533890
51regulation of neuronal synaptic plasticity (GO:0048168)2.99605906
52cell communication involved in cardiac conduction (GO:0086065)2.99598705
53regulation of NFAT protein import into nucleus (GO:0051532)2.99043331
54cytoskeletal anchoring at plasma membrane (GO:0007016)2.98803940
55neuromuscular process controlling balance (GO:0050885)2.97216242
56glial cell proliferation (GO:0014009)2.96715703
57innervation (GO:0060384)2.95175055
58positive regulation of dendritic spine morphogenesis (GO:0061003)2.95055478
59barbed-end actin filament capping (GO:0051016)2.94958823
60regulation of long-term neuronal synaptic plasticity (GO:0048169)2.94088517
61response to pheromone (GO:0019236)2.92410573
62nerve growth factor signaling pathway (GO:0038180)2.92361152
63auditory behavior (GO:0031223)2.91940163
64central nervous system neuron axonogenesis (GO:0021955)2.91888649
65organelle transport along microtubule (GO:0072384)2.91754114
66cerebellum development (GO:0021549)2.91478017
67neuron projection extension (GO:1990138)2.90350375
68negative regulation of potassium ion transmembrane transport (GO:1901380)2.88717658
69regulation of axon extension (GO:0030516)2.86312247
70regulation of synaptic vesicle transport (GO:1902803)2.86058355
71dendritic spine organization (GO:0097061)2.85753053
72cell junction maintenance (GO:0034331)2.84289316
73cardiac myofibril assembly (GO:0055003)2.83976381
74ionotropic glutamate receptor signaling pathway (GO:0035235)2.83163004
75semaphorin-plexin signaling pathway (GO:0071526)2.83098691
76neurotransmitter secretion (GO:0007269)2.81016572
77negative regulation of catenin import into nucleus (GO:0035414)2.80793118
78negative regulation of erythrocyte differentiation (GO:0045647)2.79258561
79cAMP biosynthetic process (GO:0006171)2.78974874
80positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.78858029
81nucleus localization (GO:0051647)2.78642217
82membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.77871248
83regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.75648661
84positive regulation of potassium ion transmembrane transport (GO:1901381)2.74997314
85membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.74726214
86neuronal ion channel clustering (GO:0045161)2.74625717
87regulation of membrane repolarization (GO:0060306)2.73942506
88negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.72846044
89regulation of axon extension involved in axon guidance (GO:0048841)2.71622628
90regulation of neuron migration (GO:2001222)2.71602932
91positive regulation of cellular amide metabolic process (GO:0034250)2.71345123
92positive regulation of dendritic spine development (GO:0060999)2.69427130
93regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.68796837
94endothelial cell chemotaxis (GO:0035767)2.67925268
95G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.67723928
96regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.67331532
97regulation of axon guidance (GO:1902667)2.66012255
98membrane repolarization (GO:0086009)2.65244576
99regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.64237962
100synapse organization (GO:0050808)2.63809440
101lymph vessel development (GO:0001945)2.62920164
102cerebral cortex radially oriented cell migration (GO:0021799)2.62661017
103positive regulation of dendrite morphogenesis (GO:0050775)2.62516791
104negative regulation of axon extension (GO:0030517)2.62019159
105synaptic transmission, glutamatergic (GO:0035249)2.61848353
106regulation of synapse organization (GO:0050807)2.61091022
107cerebellar Purkinje cell differentiation (GO:0021702)2.60973821
108neuron projection morphogenesis (GO:0048812)2.60882262
109cellular potassium ion homeostasis (GO:0030007)2.60697345
110adhesion of symbiont to host cell (GO:0044650)2.60677283
111virion attachment to host cell (GO:0019062)2.60677283
112negative regulation of axonogenesis (GO:0050771)2.59949760
113negative regulation of granulocyte differentiation (GO:0030853)2.58849834
114glycosphingolipid catabolic process (GO:0046479)2.58552145
115gamma-aminobutyric acid transport (GO:0015812)2.58085962
116regulation of ARF GTPase activity (GO:0032312)2.56531702
117* negative regulation of blood vessel endothelial cell migration (GO:0043537)2.54412045
118cell migration involved in heart development (GO:0060973)2.53664525
119regulation of myeloid leukocyte mediated immunity (GO:0002886)2.53653953
120mannose metabolic process (GO:0006013)2.52469547
121Notch signaling involved in heart development (GO:0061314)2.46925494
122cellular extravasation (GO:0045123)2.46741257
123cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.45633568
124L-amino acid import (GO:0043092)2.45096474
125macrophage activation involved in immune response (GO:0002281)2.41517932
126positive regulation of mast cell degranulation (GO:0043306)2.40768958
127positive regulation of mast cell activation involved in immune response (GO:0033008)2.40768958
128positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.39451141
129retina vasculature morphogenesis in camera-type eye (GO:0061299)2.38253008
130adhesion of symbiont to host (GO:0044406)2.36432471
131vascular endothelial growth factor signaling pathway (GO:0038084)2.29875450
132neuron projection extension involved in neuron projection guidance (GO:1902284)2.29572132
133axon extension involved in axon guidance (GO:0048846)2.29572132
134regulation of leukocyte degranulation (GO:0043300)2.29555595
135positive regulation of mast cell activation (GO:0033005)2.29120762
136regulation of chemokine-mediated signaling pathway (GO:0070099)2.28748925
137positive regulation of Rap GTPase activity (GO:0032854)2.27677039
138regulation of mast cell degranulation (GO:0043304)2.27378325
139positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.26880352
140glycolipid catabolic process (GO:0019377)2.26778619
141venous blood vessel morphogenesis (GO:0048845)2.24430874
142chondroitin sulfate catabolic process (GO:0030207)2.23781596
143apoptotic cell clearance (GO:0043277)2.23726444
144response to muramyl dipeptide (GO:0032495)2.23150881
145cortical actin cytoskeleton organization (GO:0030866)2.20832000
146cellular response to catecholamine stimulus (GO:0071870)2.20666724
147cellular response to monoamine stimulus (GO:0071868)2.20666724
148positive regulation of receptor recycling (GO:0001921)2.20564772
149dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.18469747
150camera-type eye morphogenesis (GO:0048593)2.13865974
151regulation of cholesterol storage (GO:0010885)2.13826361
152Rap protein signal transduction (GO:0032486)2.09613840
153regulation of T-helper 2 cell differentiation (GO:0045628)2.09043054
154heart valve formation (GO:0003188)2.07566210
155ceramide catabolic process (GO:0046514)2.06945002
156regulation of mast cell activation involved in immune response (GO:0033006)2.06751884
157neuron remodeling (GO:0016322)2.06725781
158cortical cytoskeleton organization (GO:0030865)2.05424633
159cellular response to thyroid hormone stimulus (GO:0097067)2.04545993
160modulation by symbiont of host immune response (GO:0052553)2.04497584
161positive regulation by symbiont of host defense response (GO:0052509)2.04497584
162modulation by symbiont of host defense response (GO:0052031)2.04497584
163modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.04497584
164modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.04497584
165positive regulation by organism of defense response of other organism involved in symbiotic interact2.04497584
166regulation of Rap GTPase activity (GO:0032317)2.04022551
167cellular response to epinephrine stimulus (GO:0071872)2.03989473
168response to nerve growth factor (GO:1990089)2.03222798
169cellular response to nerve growth factor stimulus (GO:1990090)2.03222798
170glomerular filtration (GO:0003094)2.02955075
171presynaptic membrane organization (GO:0097090)2.01842842

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.06406138
2BP1_19119308_ChIP-ChIP_Hs578T_Human3.69142019
3THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.97713685
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.80426596
5RNF2_18974828_ChIP-Seq_MESCs_Mouse2.69261788
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.69261788
7EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.67333506
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.64921913
9* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.58050622
10DROSHA_22980978_ChIP-Seq_HELA_Human2.54073681
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.54005586
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.44298040
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.34648791
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.31261147
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.29427844
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25365905
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.24375899
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.22442675
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.17163116
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16882077
21* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.16862201
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.16041640
23* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.11811415
24REST_21632747_ChIP-Seq_MESCs_Mouse2.11657990
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.08936060
26ZFP281_18757296_ChIP-ChIP_E14_Mouse2.08401521
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.05191937
28* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.98381277
29KDM2B_26808549_Chip-Seq_K562_Human1.98227246
30CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.98190869
31GBX2_23144817_ChIP-Seq_PC3_Human1.98005591
32WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.93001412
33* REST_18959480_ChIP-ChIP_MESCs_Mouse1.76083128
34TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.74299229
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73132200
36RING1B_27294783_Chip-Seq_ESCs_Mouse1.67731685
37KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66042658
38ZFP281_27345836_Chip-Seq_ESCs_Mouse1.64406964
39AR_21572438_ChIP-Seq_LNCaP_Human1.64335141
40ERG_21242973_ChIP-ChIP_JURKAT_Human1.60166744
41* RING1B_27294783_Chip-Seq_NPCs_Mouse1.59404809
42SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.56842597
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.54368866
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.53653959
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53504989
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.53465434
47KDM2B_26808549_Chip-Seq_DND41_Human1.47711324
48EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.47699413
49* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.44684909
50OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.43850415
51DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.42748368
52* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.42498088
53ZNF263_19887448_ChIP-Seq_K562_Human1.41941379
54ZNF274_21170338_ChIP-Seq_K562_Hela1.39779320
55ELK3_25401928_ChIP-Seq_HUVEC_Human1.37037300
56KDM2B_26808549_Chip-Seq_JURKAT_Human1.35089599
57VDR_21846776_ChIP-Seq_THP-1_Human1.33682236
58SPI1_23127762_ChIP-Seq_K562_Human1.31054053
59TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30322755
60TCF7_22412390_ChIP-Seq_EML_Mouse1.29002442
61IRF8_27001747_Chip-Seq_BMDM_Mouse1.27137205
62DNAJC2_21179169_ChIP-ChIP_NT2_Human1.26573077
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.26275310
64EP300_21415370_ChIP-Seq_HL-1_Mouse1.23374229
65SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21695035
66AR_19668381_ChIP-Seq_PC3_Human1.19571391
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.19353879
68SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.18661682
69RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.18345721
70SOX2_21211035_ChIP-Seq_LN229_Gbm1.17938418
71IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17116846
72YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14897478
73TP53_20018659_ChIP-ChIP_R1E_Mouse1.14396946
74ESR2_21235772_ChIP-Seq_MCF-7_Human1.13040924
75CBX2_27304074_Chip-Seq_ESCs_Mouse1.12905537
76RARG_19884340_ChIP-ChIP_MEFs_Mouse1.12714700
77NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11589196
78VDR_24787735_ChIP-Seq_THP-1_Human1.11455810
79SMC4_20622854_ChIP-Seq_HELA_Human1.09642264
80ISL1_27105846_Chip-Seq_CPCs_Mouse1.09187816
81GATA1_19941827_ChIP-Seq_MEL_Mouse1.09013267
82SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07605114
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06771706
84* LXR_22292898_ChIP-Seq_THP-1_Human1.04905383
85NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.04724930
86VDR_24763502_ChIP-Seq_THP-1_Human1.04692580
87ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04109830
88* CTCF_27219007_Chip-Seq_Bcells_Human1.03915642
89* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03878061
90SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03488836
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.02999332
92SCL_19346495_ChIP-Seq_HPC-7_Human1.02605703
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02352069
94PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01209638
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00207321
96SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99721956
97* SMAD4_21741376_ChIP-Seq_HESCs_Human0.99491573
98AHR_22903824_ChIP-Seq_MCF-7_Human0.99115353
99P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96973670
100ARNT_22903824_ChIP-Seq_MCF-7_Human0.94674528
101SMAD3_21741376_ChIP-Seq_ESCs_Human0.93663953
102SMAD4_21799915_ChIP-Seq_A2780_Human0.93077890
103CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92201364
104P68_20966046_ChIP-Seq_HELA_Human0.91588660
105SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91339205
106KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.91320566
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91194585
108HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.90748095
109TET1_21490601_ChIP-Seq_MESCs_Mouse0.90643096
110Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.90435178
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90258025
112ESR1_20079471_ChIP-ChIP_T-47D_Human0.90134250
113CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90070523
114OCT4_19829295_ChIP-Seq_ESCs_Human0.89488347
115KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.89290638
116UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.89126945
117CREB1_26743006_Chip-Seq_LNCaP_Human0.88839833
118SMAD3_21741376_ChIP-Seq_EPCs_Human0.88622977
119WT1_19549856_ChIP-ChIP_CCG9911_Human0.88470070
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87607363
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87607363
122RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.87080711
123TBX20_22328084_ChIP-Seq_HEART_Mouse0.86565572
124TBX20_22080862_ChIP-Seq_HEART_Mouse0.86565572
125TRIM28_21343339_ChIP-Seq_HEK293_Human0.86041611
126TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84597799
127CTCF_27219007_Chip-Seq_ERYTHROID_Human0.84288162
128KLF4_19829295_ChIP-Seq_ESCs_Human0.84042765
129TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83523792
130NFIB_24661679_ChIP-Seq_LUNG_Mouse0.83479245
131SA1_27219007_Chip-Seq_ERYTHROID_Human0.82824050
132TP53_23651856_ChIP-Seq_MEFs_Mouse0.82403114
133CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.82313328
134GATA2_21666600_ChIP-Seq_HMVEC_Human0.81393926
135IRF8_22096565_ChIP-ChIP_GC-B_Human0.81305018
136E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.80761867

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.21818697
2MP0005058_abnormal_lysosome_morphology3.14497005
3MP0004270_analgesia3.09434643
4MP0003635_abnormal_synaptic_transmissio3.04738411
5MP0000778_abnormal_nervous_system3.02305009
6MP0004858_abnormal_nervous_system2.76075911
7MP0003690_abnormal_glial_cell2.69201956
8MP0002063_abnormal_learning/memory/cond2.50909727
9MP0003172_abnormal_lysosome_physiology2.46388821
10MP0003880_abnormal_central_pattern2.46358041
11MP0005423_abnormal_somatic_nervous2.42899836
12MP0003279_aneurysm2.36411619
13MP0000751_myopathy2.30167318
14MP0000604_amyloidosis2.27958023
15MP0009780_abnormal_chondrocyte_physiolo2.22522741
16MP0003724_increased_susceptibility_to2.14758367
17MP0002734_abnormal_mechanical_nocicepti2.09443229
18MP0003828_pulmonary_edema2.07077252
19MP0005409_darkened_coat_color2.04094921
20MP0009745_abnormal_behavioral_response2.02070788
21MP0002184_abnormal_innervation1.97309630
22MP0001968_abnormal_touch/_nociception1.95394355
23MP0000537_abnormal_urethra_morphology1.94144710
24MP0005623_abnormal_meninges_morphology1.94007915
25MP0002064_seizures1.91188682
26MP0004084_abnormal_cardiac_muscle1.89994147
27MP0005187_abnormal_penis_morphology1.87276900
28MP0004811_abnormal_neuron_physiology1.85753113
29MP0004215_abnormal_myocardial_fiber1.85395967
30MP0001958_emphysema1.84658645
31MP0000955_abnormal_spinal_cord1.83655432
32MP0009278_abnormal_bone_marrow1.81835368
33MP0001879_abnormal_lymphatic_vessel1.81798780
34MP0000920_abnormal_myelination1.81065712
35MP0002837_dystrophic_cardiac_calcinosis1.80945811
36MP0002735_abnormal_chemical_nociception1.80222843
37MP0000343_altered_response_to1.76976793
38MP0003300_gastrointestinal_ulcer1.74226084
39MP0001486_abnormal_startle_reflex1.71212903
40MP0002572_abnormal_emotion/affect_behav1.69112425
41MP0005595_abnormal_vascular_smooth1.68831195
42MP0002733_abnormal_thermal_nociception1.68502122
43MP0003075_altered_response_to1.67301295
44MP0009840_abnormal_foam_cell1.65123697
45MP0003329_amyloid_beta_deposits1.64514014
46MP0009046_muscle_twitch1.63530308
47MP0003137_abnormal_impulse_conducting1.61216443
48MP0004885_abnormal_endolymph1.59681993
49MP0003283_abnormal_digestive_organ1.59006261
50MP0000569_abnormal_digit_pigmentation1.55816281
51MP0002882_abnormal_neuron_morphology1.52739592
52MP0002067_abnormal_sensory_capabilities1.52546150
53MP0002557_abnormal_social/conspecific_i1.45420140
54MP0002909_abnormal_adrenal_gland1.45050110
55MP0002152_abnormal_brain_morphology1.44184854
56MP0001440_abnormal_grooming_behavior1.39606999
57MP0002419_abnormal_innate_immunity1.39193657
58MP0002653_abnormal_ependyma_morphology1.38824854
59MP0002998_abnormal_bone_remodeling1.38444214
60MP0000767_abnormal_smooth_muscle1.38257313
61MP0003879_abnormal_hair_cell1.37468598
62MP0004085_abnormal_heartbeat1.37439022
63MP0002736_abnormal_nociception_after1.37312358
64MP0003861_abnormal_nervous_system1.36388187
65MP0002234_abnormal_pharynx_morphology1.36012948
66MP0004145_abnormal_muscle_electrophysio1.35239905
67MP0001970_abnormal_pain_threshold1.34800226
68MP0004510_myositis1.33381985
69MP0008569_lethality_at_weaning1.31611355
70MP0003436_decreased_susceptibility_to1.30111864
71MP0004924_abnormal_behavior1.26875171
72MP0005386_behavior/neurological_phenoty1.26875171
73MP0006082_CNS_inflammation1.26844251
74MP0003091_abnormal_cell_migration1.25522247
75MP0002272_abnormal_nervous_system1.25164856
76MP0003634_abnormal_glial_cell1.22104294
77MP0008004_abnormal_stomach_pH1.20694444
78MP0006276_abnormal_autonomic_nervous1.19772419
79MP0004130_abnormal_muscle_cell1.19316038
80MP0008961_abnormal_basal_metabolism1.19056656
81MP0005248_abnormal_Harderian_gland1.18334404
82MP0004233_abnormal_muscle_weight1.18190513
83MP0003183_abnormal_peptide_metabolism1.17900259
84MP0002249_abnormal_larynx_morphology1.17062586
85MP0002066_abnormal_motor_capabilities/c1.16748681
86MP0003705_abnormal_hypodermis_morpholog1.15758768
87MP0001533_abnormal_skeleton_physiology1.15550850
88MP0004036_abnormal_muscle_relaxation1.14243483
89MP0003122_maternal_imprinting1.13416148
90MP0004087_abnormal_muscle_fiber1.11534981
91MP0005166_decreased_susceptibility_to1.08508171
92MP0003119_abnormal_digestive_system1.07468940
93MP0001299_abnormal_eye_distance/1.05565160
94MP0004272_abnormal_basement_membrane1.00614582
95MP0003787_abnormal_imprinting1.00336622
96MP0010368_abnormal_lymphatic_system1.00302644
97MP0001502_abnormal_circadian_rhythm1.00244611
98MP0005670_abnormal_white_adipose0.99770774
99MP0000249_abnormal_blood_vessel0.99165904
100MP0002972_abnormal_cardiac_muscle0.98737868
101MP0006072_abnormal_retinal_apoptosis0.98506607
102MP0001348_abnormal_lacrimal_gland0.97397950
103MP0005076_abnormal_cell_differentiation0.96914820
104MP0002089_abnormal_postnatal_growth/wei0.94130874
105MP0000534_abnormal_ureter_morphology0.93620610
106MP0002896_abnormal_bone_mineralization0.93416665
107MP0006138_congestive_heart_failure0.93065750
108MP0005397_hematopoietic_system_phenotyp0.92966291
109MP0001545_abnormal_hematopoietic_system0.92966291
110MP0000631_abnormal_neuroendocrine_gland0.92340229
111MP0005671_abnormal_response_to0.92253125
112MP0003633_abnormal_nervous_system0.91968742
113MP0005620_abnormal_muscle_contractility0.91203364
114MP0002752_abnormal_somatic_nervous0.90876810
115MP0003632_abnormal_nervous_system0.89874532
116MP0005330_cardiomyopathy0.89645617
117MP0005388_respiratory_system_phenotype0.89486300
118MP0002133_abnormal_respiratory_system0.89486300
119MP0005499_abnormal_olfactory_system0.88336589
120MP0005394_taste/olfaction_phenotype0.88336589
121MP0003631_nervous_system_phenotype0.87255753
122MP0005167_abnormal_blood-brain_barrier0.86514574
123MP0001984_abnormal_olfaction0.85865736
124MP0003303_peritoneal_inflammation0.85745889
125MP0010630_abnormal_cardiac_muscle0.85740141
126MP0005025_abnormal_response_to0.84141781
127MP0008874_decreased_physiological_sensi0.83269459
128MP0002081_perinatal_lethality0.83180558
129MP0004484_altered_response_of0.83046915
130MP0000465_gastrointestinal_hemorrhage0.82510988
131MP0003115_abnormal_respiratory_system0.82334499
132MP0001790_abnormal_immune_system0.81376142
133MP0005387_immune_system_phenotype0.81376142
134MP0000747_muscle_weakness0.80594408
135MP0005551_abnormal_eye_electrophysiolog0.80393497
136MP0002148_abnormal_hypersensitivity_rea0.80342654
137MP0003385_abnormal_body_wall0.80017915
138MP0000026_abnormal_inner_ear0.78951615
139MP0000733_abnormal_muscle_development0.76913202
140MP0002822_catalepsy0.76864390
141MP0001544_abnormal_cardiovascular_syste0.76618724
142MP0005385_cardiovascular_system_phenoty0.76618724
143MP0008775_abnormal_heart_ventricle0.75298436
144MP0001986_abnormal_taste_sensitivity0.75002850
145* MP0001614_abnormal_blood_vessel0.73672076
146MP0002138_abnormal_hepatobiliary_system0.72496339
147MP0002127_abnormal_cardiovascular_syste0.72375826
148MP0005464_abnormal_platelet_physiology0.71688325
149MP0001849_ear_inflammation0.71628014
150MP0002933_joint_inflammation0.71469110
151MP0005195_abnormal_posterior_eye0.71103255
152MP0002106_abnormal_muscle_physiology0.70948830
153MP0003938_abnormal_ear_development0.70723058
154MP0002971_abnormal_brown_adipose0.68889571
155MP0004883_abnormal_blood_vessel0.68658555
156MP0001963_abnormal_hearing_physiology0.65425353
157MP0002295_abnormal_pulmonary_circulatio0.64448297

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)4.46651950
2Spontaneous hematomas (HP:0007420)4.01349148
3Abnormality of glycolipid metabolism (HP:0010969)3.74742557
4Abnormality of liposaccharide metabolism (HP:0010968)3.74742557
5Abnormality of glycosphingolipid metabolism (HP:0004343)3.74742557
6Hyperacusis (HP:0010780)3.56984960
7Myokymia (HP:0002411)3.56094477
8Esophageal varix (HP:0002040)3.50390862
9Insomnia (HP:0100785)3.44085644
10Termporal pattern (HP:0011008)3.22766740
11Insidious onset (HP:0003587)3.22766740
12Elfin facies (HP:0004428)3.21706730
13Supranuclear gaze palsy (HP:0000605)3.21124702
14Vacuolated lymphocytes (HP:0001922)3.20398641
15Abnormality of the lower motor neuron (HP:0002366)3.15460505
16Glomerulonephritis (HP:0000099)3.00136048
17Overriding aorta (HP:0002623)2.96973337
18Visual hallucinations (HP:0002367)2.90522867
19Increased cerebral lipofuscin (HP:0011813)2.87531136
20Action tremor (HP:0002345)2.85961265
21Amyotrophic lateral sclerosis (HP:0007354)2.83874006
22Renal duplication (HP:0000075)2.83364700
23Focal seizures (HP:0007359)2.81979570
24Mutism (HP:0002300)2.81926524
25Disinhibition (HP:0000734)2.80645646
26Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.78712225
27Renovascular hypertension (HP:0100817)2.77183294
28Sudden death (HP:0001699)2.76592617
29Dysostosis multiplex (HP:0000943)2.68927299
30Hematochezia (HP:0002573)2.68891791
31Ankle clonus (HP:0011448)2.68582165
32Short 4th metacarpal (HP:0010044)2.62678148
33Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.62678148
34Axonal loss (HP:0003447)2.61355012
35Pointed chin (HP:0000307)2.60927688
36Megalencephaly (HP:0001355)2.58002136
37Neuronal loss in central nervous system (HP:0002529)2.55200882
38Abnormality of the corticospinal tract (HP:0002492)2.54626428
39Shallow orbits (HP:0000586)2.52700066
40Complement deficiency (HP:0004431)2.46294945
41Cortical dysplasia (HP:0002539)2.44474231
42Flat cornea (HP:0007720)2.44186422
43Vitreoretinal degeneration (HP:0000655)2.42740074
44Abnormality of macrophages (HP:0004311)2.41479389
45Progressive cerebellar ataxia (HP:0002073)2.38793907
46Nuclear cataract (HP:0100018)2.38668012
47Urinary urgency (HP:0000012)2.36732886
48Pachygyria (HP:0001302)2.36513573
49Excessive salivation (HP:0003781)2.35107475
50Drooling (HP:0002307)2.35107475
51Cerebral inclusion bodies (HP:0100314)2.33872177
52Ventricular fibrillation (HP:0001663)2.33276852
53Genetic anticipation (HP:0003743)2.32499380
54Turricephaly (HP:0000262)2.30722464
55Difficulty running (HP:0009046)2.29459479
56Abnormality of the 4th metacarpal (HP:0010012)2.28716091
57Lymphangioma (HP:0100764)2.27507185
58Sacral dimple (HP:0000960)2.25987278
59Visceral angiomatosis (HP:0100761)2.25037911
60Thin bony cortex (HP:0002753)2.23745503
61Epileptic encephalopathy (HP:0200134)2.23656809
62Urinary bladder sphincter dysfunction (HP:0002839)2.22589741
63Apathy (HP:0000741)2.21855442
64Abnormality of the vasculature of the conjunctiva (HP:0008054)2.21726869
65Loss of speech (HP:0002371)2.19786129
66Focal motor seizures (HP:0011153)2.18478873
67Bundle branch block (HP:0011710)2.18469283
68Obstructive sleep apnea (HP:0002870)2.17738770
69Inappropriate behavior (HP:0000719)2.17551854
70Depression (HP:0000716)2.16232137
71Poor eye contact (HP:0000817)2.15094657
72Amyloidosis (HP:0011034)2.15068408
73Recurrent abscess formation (HP:0002722)2.12052871
74Hepatoblastoma (HP:0002884)2.11758790
75Conjunctival telangiectasia (HP:0000524)2.11619764
76Eczematoid dermatitis (HP:0000976)2.10813691
77Macroorchidism (HP:0000053)2.10537703
78Prolonged QT interval (HP:0001657)2.09560768
79Aplasia/Hypoplasia of the brainstem (HP:0007362)2.09545946
80Hypoplasia of the brainstem (HP:0002365)2.09545946
81Aqueductal stenosis (HP:0002410)2.08161921
82Broad-based gait (HP:0002136)2.08128704
83Increased neuronal autofluorescent lipopigment (HP:0002074)2.07454056
84Recurrent bacterial skin infections (HP:0005406)2.06465787
85Impaired vibration sensation in the lower limbs (HP:0002166)2.04254989
86Hemiparesis (HP:0001269)2.04224405
87Thoracic kyphosis (HP:0002942)2.03468198
88Abnormality of the diencephalon (HP:0010662)2.01646221
89Overgrowth (HP:0001548)2.01566351
90Neurofibrillary tangles (HP:0002185)2.01559632
91Recurrent gram-negative bacterial infections (HP:0005420)2.01193260
92Abnormal social behavior (HP:0012433)2.00525396
93Impaired social interactions (HP:0000735)2.00525396
94Upper motor neuron abnormality (HP:0002127)1.99692926
95Abnormality of polysaccharide metabolism (HP:0011012)1.99527386
96Abnormality of glycosaminoglycan metabolism (HP:0004371)1.99527386
97Abnormality of mucopolysaccharide metabolism (HP:0011020)1.99527386
98Bladder diverticulum (HP:0000015)1.99484377
99Diplopia (HP:0000651)1.97787870
100Abnormality of binocular vision (HP:0011514)1.97787870
101Bowel diverticulosis (HP:0005222)1.97039508
102Dementia (HP:0000726)1.96956680
103Papilledema (HP:0001085)1.96046149
104Hemangiomatosis (HP:0007461)1.95853090
105Lower limb muscle weakness (HP:0007340)1.95783052
106Amblyopia (HP:0000646)1.95097112
107Spastic gait (HP:0002064)1.95022408
108Neoplasm of the heart (HP:0100544)1.94806586
109Asymmetric septal hypertrophy (HP:0001670)1.93742006
110Abnormality of the periventricular white matter (HP:0002518)1.93380757
111Buphthalmos (HP:0000557)1.91510205
112Lower limb amyotrophy (HP:0007210)1.91296186
113Diminished motivation (HP:0000745)1.91262032
114Retinal atrophy (HP:0001105)1.90932374
115Pulmonary hypertension (HP:0002092)1.90408047
116Hemiplegia (HP:0002301)1.90339323
117Abnormality of complement system (HP:0005339)1.90079578
118Rapidly progressive (HP:0003678)1.90040623
119Polygenic inheritance (HP:0010982)1.89798377
120Protuberant abdomen (HP:0001538)1.88701544
121Urinary glycosaminoglycan excretion (HP:0003541)1.87458675
122Mucopolysacchariduria (HP:0008155)1.87458675
123Annular pancreas (HP:0001734)1.85318698
124Pheochromocytoma (HP:0002666)1.85024833
125Megalocornea (HP:0000485)1.84492325
126Limb dystonia (HP:0002451)1.83800750
127Thin ribs (HP:0000883)1.83246600
128Abnormal eating behavior (HP:0100738)1.82933559
129Primary atrial arrhythmia (HP:0001692)1.82209036
130Disproportionate tall stature (HP:0001519)1.81474303
131Abnormality of the astrocytes (HP:0100707)1.81371070
132Astrocytoma (HP:0009592)1.81371070
133Polyphagia (HP:0002591)1.81149478
134Obsessive-compulsive behavior (HP:0000722)1.80937881
135Truncal ataxia (HP:0002078)1.80559651
136Central scotoma (HP:0000603)1.78187559
137Atrial fibrillation (HP:0005110)1.77449413
138Wrist flexion contracture (HP:0001239)1.77362202
139Intellectual disability, profound (HP:0002187)1.76659025
140Myotonia (HP:0002486)1.76342146
141Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.75976324
142Hemoptysis (HP:0002105)1.75621857
143Aneurysm (HP:0002617)1.75575390
144Supraventricular arrhythmia (HP:0005115)1.73412347
145Syncope (HP:0001279)1.73058914
146Peripheral hypomyelination (HP:0007182)1.73015421
147Germ cell neoplasia (HP:0100728)1.72942426
148Hyporeflexia of lower limbs (HP:0002600)1.72837007
149Increased variability in muscle fiber diameter (HP:0003557)1.72539638
150Hammertoe (HP:0001765)1.72532191
151Subacute progressive viral hepatitis (HP:0006572)1.71739525
152Cerebral aneurysm (HP:0004944)1.71584506
153Back pain (HP:0003418)1.71271595
154Adactyly (HP:0009776)1.71261514
155Agitation (HP:0000713)1.70440664
156Neoplasm of the peripheral nervous system (HP:0100007)1.69312633
157Nephritis (HP:0000123)1.68716140
158Cerebral hemorrhage (HP:0001342)1.68552721
159Mitral valve prolapse (HP:0001634)1.68349271
160Enlarged penis (HP:0000040)1.68275731
161Supraventricular tachycardia (HP:0004755)1.68091908
162Myocardial infarction (HP:0001658)1.67595086
163Abnormal EKG (HP:0003115)1.67442570
164Stereotypic behavior (HP:0000733)1.66156294
165Gingivitis (HP:0000230)1.65189315
166Abnormality of the ischium (HP:0003174)1.64747203
167Hypsarrhythmia (HP:0002521)1.64164722
168Akinesia (HP:0002304)1.64067369

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.00896647
2MAP3K92.90456486
3PAK62.58309456
4PHKG22.34723334
5PHKG12.34723334
6TRIB32.26447855
7NTRK22.26297636
8NTRK32.18483221
9BLK2.15708119
10MINK12.11124683
11MAP3K42.08382958
12KSR12.07933091
13EPHB21.98274158
14PKN21.96395777
15SIK21.88904085
16PRKD31.75750936
17TGFBR21.75193285
18TYRO31.70402346
19LATS21.69809465
20ICK1.68112635
21PRPF4B1.63926254
22DDR21.58992296
23RIPK11.57822925
24RIPK41.52736263
25MAP3K101.50929637
26DYRK21.50242411
27DAPK21.49913441
28KSR21.49491471
29FGR1.48990417
30CAMKK11.48490222
31NTRK11.45136400
32UHMK11.44447480
33CASK1.43347233
34EPHA41.39239701
35KDR1.38898022
36LMTK21.38869832
37CAMK1G1.38045540
38MAPK131.35274623
39SCYL21.34783861
40CSK1.34581827
41SGK21.33165704
42CSF1R1.27399214
43PDGFRA1.27311094
44RET1.27159391
45CDK51.24675947
46SGK31.21911617
47PAK31.21227161
48FGFR21.18430900
49ALK1.12327783
50DMPK1.10892301
51ERBB31.07927154
52MAP3K111.05638539
53TYK21.05593615
54MAP3K131.05334441
55MAP2K71.02946894
56CSNK1G20.98264985
57LIMK10.97980643
58MARK20.97768076
59PNCK0.96429508
60MAP2K40.94025597
61CDK150.90559741
62MOS0.89245074
63CDK140.88181034
64CDK180.87459737
65TIE10.87441029
66STK110.86149067
67TAOK10.85789568
68JAK30.84274179
69TNK20.81613727
70EEF2K0.81538263
71ERBB20.80166288
72CDK11A0.79114211
73MAPK70.78831873
74NEK10.78278819
75PKN10.77718618
76PTK60.77160589
77CDC42BPA0.77137626
78ZAP700.76969407
79MAP2K30.76487004
80ILK0.75225417
81CAMKK20.75082090
82PRKCH0.74717489
83MAP4K10.73384214
84PRKD20.73009048
85PDPK10.72022534
86RPS6KL10.70896863
87RPS6KC10.70896863
88TTN0.70601102
89CSNK1A1L0.68318722
90PRKCZ0.68160764
91EPHB10.67611115
92CAMK1D0.67300393
93DYRK1A0.66625965
94MAP3K60.63347023
95EPHA30.63253031
96CSNK1G30.63227222
97ROCK10.61981693
98HCK0.61198269
99PLK20.60898480
100GRK70.60468615
101JAK20.60159724
102MAP3K10.59472751
103RPS6KA20.58448709
104MAPK150.56320843
105STK380.55419370
106RPS6KA60.54530147
107PRKAA10.54081391
108DYRK1B0.53982807
109PDGFRB0.53814685
110PRKD10.53799134
111MAP3K20.52855697
112ERN10.52712119
113JAK10.52583050
114MAPK120.51821470
115PRKCG0.51273150
116FYN0.50360991
117MAPK90.49985865
118TNIK0.48855679
119MTOR0.48751439
120PDK10.48702229
121MAP3K30.47314910
122SIK10.46362592
123SGK2230.45967023
124SGK4940.45967023
125CAMK2A0.45678072
126PTK2B0.45151276
127FGFR40.44108769
128PAK20.43019233
129FER0.42660050
130MAPK40.42338757
131RPS6KA30.42291490
132SYK0.41502913
133SRC0.40948233
134ROCK20.40854428
135CAMK40.40430639
136CSNK1D0.39673231
137DAPK10.38520705
138FES0.38320286
139MAPK100.38241322
140MAPK80.37781234
141CAMK10.37769348
142FGFR10.36188162
143SGK10.35551668
144MAP3K70.34805739
145TGFBR10.34575310

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.30678191
2Axon guidance_Homo sapiens_hsa043602.07379101
3Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02876752
4Circadian entrainment_Homo sapiens_hsa047132.01492340
5Staphylococcus aureus infection_Homo sapiens_hsa051501.98495431
6Synaptic vesicle cycle_Homo sapiens_hsa047211.95704186
7Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.87573070
8Nicotine addiction_Homo sapiens_hsa050331.84075332
9Glutamatergic synapse_Homo sapiens_hsa047241.81528945
10GABAergic synapse_Homo sapiens_hsa047271.77791202
11Long-term potentiation_Homo sapiens_hsa047201.77445356
12Lysosome_Homo sapiens_hsa041421.69798192
13Olfactory transduction_Homo sapiens_hsa047401.68809534
14Dopaminergic synapse_Homo sapiens_hsa047281.68479668
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66646122
16Cholinergic synapse_Homo sapiens_hsa047251.65671074
17Osteoclast differentiation_Homo sapiens_hsa043801.62851376
18Dilated cardiomyopathy_Homo sapiens_hsa054141.59837365
19Glioma_Homo sapiens_hsa052141.55680909
20Morphine addiction_Homo sapiens_hsa050321.55504760
21Gap junction_Homo sapiens_hsa045401.50529601
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50015698
23Phagosome_Homo sapiens_hsa041451.47692043
24Type II diabetes mellitus_Homo sapiens_hsa049301.46817602
25Oxytocin signaling pathway_Homo sapiens_hsa049211.46572459
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46499945
27Leishmaniasis_Homo sapiens_hsa051401.46009912
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.45721997
29Estrogen signaling pathway_Homo sapiens_hsa049151.44832969
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.44173593
31Endometrial cancer_Homo sapiens_hsa052131.43008397
32Gastric acid secretion_Homo sapiens_hsa049711.40013683
33Renin secretion_Homo sapiens_hsa049241.37823690
34Insulin secretion_Homo sapiens_hsa049111.37426489
35Amphetamine addiction_Homo sapiens_hsa050311.35191869
36Tuberculosis_Homo sapiens_hsa051521.34905769
37Salivary secretion_Homo sapiens_hsa049701.32340667
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.28165938
39Viral myocarditis_Homo sapiens_hsa054161.25942704
40ErbB signaling pathway_Homo sapiens_hsa040121.25915187
41GnRH signaling pathway_Homo sapiens_hsa049121.24641452
42Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.24423521
43Dorso-ventral axis formation_Homo sapiens_hsa043201.23386732
44Colorectal cancer_Homo sapiens_hsa052101.22777924
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22100934
46Renal cell carcinoma_Homo sapiens_hsa052111.22056547
47Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.18559988
48Pertussis_Homo sapiens_hsa051331.18024646
49Cocaine addiction_Homo sapiens_hsa050301.17697600
50Chemokine signaling pathway_Homo sapiens_hsa040621.16807916
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.15330812
52Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.14590067
53Long-term depression_Homo sapiens_hsa047301.14212960
54Melanogenesis_Homo sapiens_hsa049161.13757171
55Neurotrophin signaling pathway_Homo sapiens_hsa047221.12877736
56VEGF signaling pathway_Homo sapiens_hsa043701.12626383
57cGMP-PKG signaling pathway_Homo sapiens_hsa040221.11703611
58Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.10624586
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.09866242
60Thyroid hormone signaling pathway_Homo sapiens_hsa049191.07284264
61Amoebiasis_Homo sapiens_hsa051461.06893262
62mTOR signaling pathway_Homo sapiens_hsa041501.06876781
63cAMP signaling pathway_Homo sapiens_hsa040241.06350944
64Rheumatoid arthritis_Homo sapiens_hsa053231.06244957
65Phospholipase D signaling pathway_Homo sapiens_hsa040720.99487457
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.97271021
67B cell receptor signaling pathway_Homo sapiens_hsa046620.97140133
68Notch signaling pathway_Homo sapiens_hsa043300.95485868
69Cardiac muscle contraction_Homo sapiens_hsa042600.94738376
70Platelet activation_Homo sapiens_hsa046110.94649462
71Serotonergic synapse_Homo sapiens_hsa047260.94102688
72Non-small cell lung cancer_Homo sapiens_hsa052230.92748652
73Calcium signaling pathway_Homo sapiens_hsa040200.92301337
74Basal cell carcinoma_Homo sapiens_hsa052170.91600210
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.90922313
76Collecting duct acid secretion_Homo sapiens_hsa049660.90742292
77Hippo signaling pathway_Homo sapiens_hsa043900.90000605
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89475947
79Focal adhesion_Homo sapiens_hsa045100.89310322
80Taste transduction_Homo sapiens_hsa047420.89113471
81Chronic myeloid leukemia_Homo sapiens_hsa052200.88678680
82Toll-like receptor signaling pathway_Homo sapiens_hsa046200.88469387
83Hedgehog signaling pathway_Homo sapiens_hsa043400.87762369
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86848945
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.86284389
86Oocyte meiosis_Homo sapiens_hsa041140.85991535
87Toxoplasmosis_Homo sapiens_hsa051450.85573328
88Salmonella infection_Homo sapiens_hsa051320.84573539
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84476537
90Insulin signaling pathway_Homo sapiens_hsa049100.83441985
91Tight junction_Homo sapiens_hsa045300.82749112
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.82394239
93Rap1 signaling pathway_Homo sapiens_hsa040150.81294509
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81243955
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.80869869
96Wnt signaling pathway_Homo sapiens_hsa043100.80752644
97Central carbon metabolism in cancer_Homo sapiens_hsa052300.79895644
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79776969
99Choline metabolism in cancer_Homo sapiens_hsa052310.79358425
100Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.77786450
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77429976
102MAPK signaling pathway_Homo sapiens_hsa040100.77363804
103Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77186237
104Malaria_Homo sapiens_hsa051440.76104909
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72957547
106Vibrio cholerae infection_Homo sapiens_hsa051100.70694831
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69540334
108Proteoglycans in cancer_Homo sapiens_hsa052050.69504596
109Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.69157145
110Endocytosis_Homo sapiens_hsa041440.68600611
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.68205638
112Nitrogen metabolism_Homo sapiens_hsa009100.67482970
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.66645883
114Ras signaling pathway_Homo sapiens_hsa040140.66557919
115Pancreatic cancer_Homo sapiens_hsa052120.66084209
116AMPK signaling pathway_Homo sapiens_hsa041520.65469911
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.65139431
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.63237905
119Prolactin signaling pathway_Homo sapiens_hsa049170.63054062
120Glucagon signaling pathway_Homo sapiens_hsa049220.62505701
121Alcoholism_Homo sapiens_hsa050340.62405511
122Hematopoietic cell lineage_Homo sapiens_hsa046400.62253808
123Acute myeloid leukemia_Homo sapiens_hsa052210.61571019
124Asthma_Homo sapiens_hsa053100.61432767
125Complement and coagulation cascades_Homo sapiens_hsa046100.61364366
126MicroRNAs in cancer_Homo sapiens_hsa052060.61150430
127Adherens junction_Homo sapiens_hsa045200.60307622
128Phototransduction_Homo sapiens_hsa047440.60205838
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59493662
130Prion diseases_Homo sapiens_hsa050200.59492242
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59441964
132ECM-receptor interaction_Homo sapiens_hsa045120.59306793
133Allograft rejection_Homo sapiens_hsa053300.52919635

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