UTP6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)5.58303935
2embryonic process involved in female pregnancy (GO:0060136)4.94137928
3replication fork processing (GO:0031297)4.86502013
4somatic hypermutation of immunoglobulin genes (GO:0016446)4.78139289
5somatic diversification of immune receptors via somatic mutation (GO:0002566)4.78139289
6transcription from mitochondrial promoter (GO:0006390)4.65255199
7DNA replication checkpoint (GO:0000076)4.61545031
8nuclear pore organization (GO:0006999)4.59210803
9regulation of translational fidelity (GO:0006450)4.56682444
10nuclear pore complex assembly (GO:0051292)4.42069818
11formation of translation preinitiation complex (GO:0001731)4.37687797
12maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.37509376
13regulation of RNA export from nucleus (GO:0046831)4.20496576
14establishment of apical/basal cell polarity (GO:0035089)4.18955981
15protein localization to kinetochore (GO:0034501)4.14276351
16proteasome assembly (GO:0043248)4.13817595
17mitotic G1 DNA damage checkpoint (GO:0031571)4.13500003
18chromatin remodeling at centromere (GO:0031055)4.11877141
19mitotic nuclear envelope disassembly (GO:0007077)4.08848630
20positive regulation of mitotic sister chromatid separation (GO:1901970)4.05517662
21positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.05517662
22positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.05517662
23CENP-A containing nucleosome assembly (GO:0034080)4.05439738
24telomere maintenance via semi-conservative replication (GO:0032201)4.01627652
25DNA unwinding involved in DNA replication (GO:0006268)4.00557648
26spliceosomal tri-snRNP complex assembly (GO:0000244)4.00028153
27dosage compensation (GO:0007549)4.00003181
28DNA strand elongation involved in DNA replication (GO:0006271)3.97713649
29proline metabolic process (GO:0006560)3.91679705
30mitotic sister chromatid segregation (GO:0000070)3.90359952
31positive regulation of chromosome segregation (GO:0051984)3.89982540
32regulation of sister chromatid cohesion (GO:0007063)3.89127734
33regulation of posttranscriptional gene silencing (GO:0060147)3.85467778
34regulation of gene silencing by miRNA (GO:0060964)3.85467778
35regulation of gene silencing by RNA (GO:0060966)3.85467778
36regulation of mitotic spindle checkpoint (GO:1903504)3.85363224
37regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.85363224
38sister chromatid segregation (GO:0000819)3.84407086
39nuclear envelope disassembly (GO:0051081)3.83031647
40membrane disassembly (GO:0030397)3.83031647
41pre-miRNA processing (GO:0031054)3.80232944
42mitochondrial DNA metabolic process (GO:0032042)3.80024698
43folic acid-containing compound biosynthetic process (GO:0009396)3.78534175
44ribosome assembly (GO:0042255)3.78092905
45DNA strand elongation (GO:0022616)3.78079362
46negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.74049005
47IMP biosynthetic process (GO:0006188)3.71412177
48DNA strand renaturation (GO:0000733)3.65470604
49mRNA cleavage (GO:0006379)3.64789838
50nucleotide-excision repair, DNA gap filling (GO:0006297)3.62397633
51DNA topological change (GO:0006265)3.60442748
52negative regulation of DNA-dependent DNA replication (GO:2000104)3.60036460
53establishment of integrated proviral latency (GO:0075713)3.58944022
54somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.57406155
55isotype switching (GO:0045190)3.57406155
56somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.57406155
57DNA duplex unwinding (GO:0032508)3.55992850
58mitotic G1/S transition checkpoint (GO:0044819)3.55147548
59DNA geometric change (GO:0032392)3.54560127
60meiotic chromosome segregation (GO:0045132)3.54376687
61establishment of monopolar cell polarity (GO:0061162)3.53301572
62establishment or maintenance of monopolar cell polarity (GO:0061339)3.53301572
63G1 DNA damage checkpoint (GO:0044783)3.50960362
64DNA replication-dependent nucleosome organization (GO:0034723)3.50858080
65DNA replication-dependent nucleosome assembly (GO:0006335)3.50858080
66negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.50512368
67DNA catabolic process, exonucleolytic (GO:0000738)3.50474667
68DNA replication initiation (GO:0006270)3.48796779
69base-excision repair (GO:0006284)3.48074225
70RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.47850195
71regulation of integrin activation (GO:0033623)3.47324852
72telomere maintenance via recombination (GO:0000722)3.46225317
73pseudouridine synthesis (GO:0001522)3.45800852
74mitotic metaphase plate congression (GO:0007080)3.42451168
75histone exchange (GO:0043486)3.42181401
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.41981086
77viral mRNA export from host cell nucleus (GO:0046784)3.41226581
78regulation of DNA damage checkpoint (GO:2000001)3.39263338
79mitochondrial RNA metabolic process (GO:0000959)3.36611088
80kinetochore organization (GO:0051383)3.36250702
81nucleobase biosynthetic process (GO:0046112)3.34858007
82exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.34208786
83cullin deneddylation (GO:0010388)3.32545515
84mitotic recombination (GO:0006312)3.32185321
85positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.31830027
86anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.31714199
87pore complex assembly (GO:0046931)3.30832739
88negative regulation of mRNA processing (GO:0050686)3.30474884
89nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.28741182
90establishment of protein localization to mitochondrial membrane (GO:0090151)3.25273621
91heterochromatin organization (GO:0070828)3.25068823
92protein K6-linked ubiquitination (GO:0085020)3.21026213
93rRNA modification (GO:0000154)3.20429325
94nuclear envelope organization (GO:0006998)3.20323550
95IMP metabolic process (GO:0046040)3.19806947
96regulation of DNA endoreduplication (GO:0032875)3.19334422
97regulation of nucleobase-containing compound transport (GO:0032239)3.17769667
98regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.17632613
99negative regulation of ligase activity (GO:0051352)3.16798335
100negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.16798335
101DNA replication-independent nucleosome organization (GO:0034724)3.15352318
102DNA replication-independent nucleosome assembly (GO:0006336)3.15352318
103kinetochore assembly (GO:0051382)3.14495333
104mRNA transport (GO:0051028)3.13772416
105protein localization to chromosome, centromeric region (GO:0071459)3.12667307
106telomere maintenance via telomere lengthening (GO:0010833)3.12226140
107somatic recombination of immunoglobulin gene segments (GO:0016447)3.12082066
108protein deneddylation (GO:0000338)3.11911888
109positive regulation of protein homooligomerization (GO:0032464)3.11509765
110ribosomal large subunit biogenesis (GO:0042273)3.11293659
111determination of adult lifespan (GO:0008340)3.10442054
112negative regulation of RNA splicing (GO:0033119)3.09921942
113spindle checkpoint (GO:0031577)3.09319215
114embryonic placenta development (GO:0001892)3.09260425
115trophectodermal cell differentiation (GO:0001829)3.08837405
116* rRNA processing (GO:0006364)3.08760437
117ribosome biogenesis (GO:0042254)3.07894138
118termination of RNA polymerase II transcription (GO:0006369)3.06681316
119histone H4-K12 acetylation (GO:0043983)3.06414082
120regulation of double-strand break repair (GO:2000779)3.05901165
121DNA deamination (GO:0045006)3.05771737
122synapsis (GO:0007129)3.05017541
123double-strand break repair via nonhomologous end joining (GO:0006303)3.04969130
124non-recombinational repair (GO:0000726)3.04969130
125regulation of double-strand break repair via homologous recombination (GO:0010569)3.04683061
126mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.04535950
127regulation of centrosome cycle (GO:0046605)3.03553944
128regulation of nuclear cell cycle DNA replication (GO:0033262)3.02795146
129oxidative demethylation (GO:0070989)3.02433267
130resolution of meiotic recombination intermediates (GO:0000712)3.02025251
131* rRNA metabolic process (GO:0016072)3.01889319
132attachment of spindle microtubules to kinetochore (GO:0008608)3.01477420
133negative regulation of fatty acid biosynthetic process (GO:0045717)3.00908372
134rRNA methylation (GO:0031167)2.99131496
135mitotic spindle checkpoint (GO:0071174)2.99020824
136respiratory chain complex IV assembly (GO:0008535)2.98194910
137somatic diversification of immunoglobulins (GO:0016445)2.98066472
138DNA double-strand break processing (GO:0000729)2.98010974
139maturation of 5.8S rRNA (GO:0000460)2.97681504
140tRNA aminoacylation (GO:0043039)2.97654247
141amino acid activation (GO:0043038)2.97654247
142histone mRNA metabolic process (GO:0008334)2.96723895
143tRNA aminoacylation for protein translation (GO:0006418)2.96247312
144DNA damage response, detection of DNA damage (GO:0042769)2.94301213
145signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.93724906
146signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.93724906
147signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.93724906
148recombinational repair (GO:0000725)2.93480424
149mitotic chromosome condensation (GO:0007076)2.93478511
150purine nucleobase biosynthetic process (GO:0009113)2.93148634
151mRNA export from nucleus (GO:0006406)2.93140198
152postreplication repair (GO:0006301)2.92748728
153regulation of centriole replication (GO:0046599)2.92595768
154DNA ligation (GO:0006266)2.92468743
155double-strand break repair via homologous recombination (GO:0000724)2.92234463
156regulation of translational termination (GO:0006449)2.92101345
157positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.91134474
158mitotic sister chromatid cohesion (GO:0007064)2.90653992
159negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.90289525
160negative regulation of mitotic sister chromatid segregation (GO:0033048)2.90289525
161negative regulation of sister chromatid segregation (GO:0033046)2.90289525
162negative regulation of chromosome segregation (GO:0051985)2.90042204
163metaphase plate congression (GO:0051310)2.89764436
164regulation of helicase activity (GO:0051095)2.89557178

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.11911222
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.38199749
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.70148219
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.21280930
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.99116146
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.98616176
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.83719351
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77109496
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.74276318
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.66431580
11SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.60616825
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.44529893
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.34344687
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.30352889
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.28582197
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.23467292
17KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.17456790
18KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.17456790
19KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.17456790
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.17295165
21FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.15967184
22MYC_22102868_ChIP-Seq_BL_Human2.13358093
23POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.08712413
24ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.06921425
25* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.03748451
26E2F1_21310950_ChIP-Seq_MCF-7_Human1.99658683
27ZNF274_21170338_ChIP-Seq_K562_Hela1.98348814
28SRF_21415370_ChIP-Seq_HL-1_Mouse1.96654871
29PADI4_21655091_ChIP-ChIP_MCF-7_Human1.91637995
30MYC_18940864_ChIP-ChIP_HL60_Human1.90388428
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85919111
32AR_21909140_ChIP-Seq_LNCAP_Human1.85836827
33NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.84924106
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.84889801
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.81054843
36ESR1_15608294_ChIP-ChIP_MCF-7_Human1.79530855
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.77188015
38NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74466377
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.72794270
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.71823771
41NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.71427326
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70917733
43DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.65510209
44XRN2_22483619_ChIP-Seq_HELA_Human1.65350381
45NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.64678987
46CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.64529270
47SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.63964543
48ETS1_20019798_ChIP-Seq_JURKAT_Human1.63100755
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.59848693
50EWS_26573619_Chip-Seq_HEK293_Human1.58116779
51KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.57460718
52TCF3_18692474_ChIP-Seq_MEFs_Mouse1.56157937
53VDR_21846776_ChIP-Seq_THP-1_Human1.55868873
54TCF3_18692474_ChIP-Seq_MESCs_Mouse1.55128845
55SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.54251878
56NANOG_21062744_ChIP-ChIP_HESCs_Human1.52616416
57KLF4_18555785_ChIP-Seq_MESCs_Mouse1.50386546
58JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.50095272
59SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.47004589
60KDM5A_27292631_Chip-Seq_BREAST_Human1.46948991
61ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45118391
62VDR_22108803_ChIP-Seq_LS180_Human1.44854486
63PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.44604576
64EST1_17652178_ChIP-ChIP_JURKAT_Human1.43658843
65ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.41362295
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.40315816
67FUS_26573619_Chip-Seq_HEK293_Human1.39735100
68DCP1A_22483619_ChIP-Seq_HELA_Human1.37832365
69* GABP_19822575_ChIP-Seq_HepG2_Human1.35816718
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.35410542
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.35383668
72THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35154006
73HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.34414438
74HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.33687145
75SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.33456963
76POU5F1_16518401_ChIP-PET_MESCs_Mouse1.33397639
77POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33141959
78VDR_23849224_ChIP-Seq_CD4+_Human1.32575870
79CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.32466863
80CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.31734641
81FLI1_27457419_Chip-Seq_LIVER_Mouse1.30775904
82IRF1_19129219_ChIP-ChIP_H3396_Human1.28053254
83TTF2_22483619_ChIP-Seq_HELA_Human1.27791486
84E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20060232
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.19830075
86PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19688214
87TFEB_21752829_ChIP-Seq_HELA_Human1.19409411
88MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.17769233
89NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.17502811
90GABP_17652178_ChIP-ChIP_JURKAT_Human1.17109614
91KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.16974763
92ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16244743
93YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15445652
94STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15341852
95CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.13862128
96POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12934419
97NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.12565010
98ZNF263_19887448_ChIP-Seq_K562_Human1.11644804
99FOXP3_21729870_ChIP-Seq_TREG_Human1.09763317
100TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09254998
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07536203
102CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07086718
103TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.06771261
104RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05857865
105SOX2_18692474_ChIP-Seq_MESCs_Mouse1.05343199
106TP63_19390658_ChIP-ChIP_HaCaT_Human1.04954160
107BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04587468
108NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.03385815
109ERG_20887958_ChIP-Seq_HPC-7_Mouse1.02375510
110* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02325310
111SOX2_18692474_ChIP-Seq_MEFs_Mouse1.00325382
112YY1_21170310_ChIP-Seq_MESCs_Mouse1.00237900
113SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.99634502
114POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.99078309
115ELK1_22589737_ChIP-Seq_MCF10A_Human0.98600343
116OCT4_18692474_ChIP-Seq_MEFs_Mouse0.98155140
117CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97052876
118EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96941543
119KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96325934
120IGF1R_20145208_ChIP-Seq_DFB_Human0.94861390
121* ELK1_19687146_ChIP-ChIP_HELA_Human0.94595307
122CHD1_26751641_Chip-Seq_LNCaP_Human0.94114244
123FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93966167
124HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.92686526
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.92015135
126NANOG_18692474_ChIP-Seq_MESCs_Mouse0.91870206
127HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.91002389
128NANOG_16153702_ChIP-ChIP_HESCs_Human0.90778352
129POU5F1_16153702_ChIP-ChIP_HESCs_Human0.90316738
130TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90176864
131EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89779303
132CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89430221
133KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.89225493
134PCGF2_27294783_Chip-Seq_ESCs_Mouse0.89143572
135IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.88592148
136CIITA_25753668_ChIP-Seq_RAJI_Human0.88300898
137TP53_22573176_ChIP-Seq_HFKS_Human0.87665880
138ZFP281_27345836_Chip-Seq_ESCs_Mouse0.85695027
139SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.84445005
140SOX2_16153702_ChIP-ChIP_HESCs_Human0.80313822
141CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.78422739
142PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75029270
143TAF15_26573619_Chip-Seq_HEK293_Human0.72584719
144GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.72137393
145* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70567122
146FOXA1_27270436_Chip-Seq_PROSTATE_Human0.69730933
147FOXA1_25329375_ChIP-Seq_VCAP_Human0.69730933
148P300_19829295_ChIP-Seq_ESCs_Human0.69536346
149MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.69534422
150SOX17_20123909_ChIP-Seq_XEN_Mouse0.66953684

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.01649442
2MP0010094_abnormal_chromosome_stability3.78467287
3MP0003111_abnormal_nucleus_morphology3.45863867
4MP0004957_abnormal_blastocyst_morpholog3.37941277
5MP0003693_abnormal_embryo_hatching3.17037483
6MP0010352_gastrointestinal_tract_polyps2.98568758
7MP0003077_abnormal_cell_cycle2.86684310
8MP0010030_abnormal_orbit_morphology2.68453216
9MP0010307_abnormal_tumor_latency2.61045849
10MP0005076_abnormal_cell_differentiation2.57165433
11MP0008058_abnormal_DNA_repair2.50938075
12MP0003705_abnormal_hypodermis_morpholog2.37447555
13MP0001730_embryonic_growth_arrest2.26172671
14MP0009278_abnormal_bone_marrow2.21276014
15MP0000372_irregular_coat_pigmentation2.19087496
16MP0009697_abnormal_copulation2.15811920
17MP0006292_abnormal_olfactory_placode2.15570251
18MP0000350_abnormal_cell_proliferation2.07036349
19MP0004197_abnormal_fetal_growth/weight/2.06310838
20MP0003890_abnormal_embryonic-extraembry2.03394136
21MP0008932_abnormal_embryonic_tissue2.00462777
22MP0002086_abnormal_extraembryonic_tissu1.98675479
23MP0001697_abnormal_embryo_size1.98557680
24MP0002084_abnormal_developmental_patter1.98135532
25MP0005380_embryogenesis_phenotype1.96632199
26MP0001672_abnormal_embryogenesis/_devel1.96632199
27MP0004233_abnormal_muscle_weight1.96608401
28MP0006035_abnormal_mitochondrial_morpho1.89860213
29MP0002085_abnormal_embryonic_tissue1.83730804
30MP0003567_abnormal_fetal_cardiomyocyte1.73900980
31MP0003984_embryonic_growth_retardation1.73240685
32MP0003786_premature_aging1.71315427
33MP0002088_abnormal_embryonic_growth/wei1.70123701
34MP0003806_abnormal_nucleotide_metabolis1.68970571
35MP0001293_anophthalmia1.67898496
36MP0002102_abnormal_ear_morphology1.65786576
37MP0008007_abnormal_cellular_replicative1.60061253
38MP0002080_prenatal_lethality1.57617598
39MP0002396_abnormal_hematopoietic_system1.55092503
40MP0006036_abnormal_mitochondrial_physio1.54692464
41MP0003186_abnormal_redox_activity1.54452690
42MP0003646_muscle_fatigue1.53079885
43MP0009053_abnormal_anal_canal1.53070957
44MP0002938_white_spotting1.51978099
45MP0002163_abnormal_gland_morphology1.49688445
46MP0005075_abnormal_melanosome_morpholog1.49318865
47MP0000358_abnormal_cell_content/1.48375420
48MP0000490_abnormal_crypts_of1.47439596
49MP0003119_abnormal_digestive_system1.46923784
50MP0003950_abnormal_plasma_membrane1.40223023
51MP0005171_absent_coat_pigmentation1.38626920
52MP0003566_abnormal_cell_adhesion1.37892948
53MP0003123_paternal_imprinting1.36765227
54MP0008877_abnormal_DNA_methylation1.36349259
55MP0005397_hematopoietic_system_phenotyp1.30686295
56MP0001545_abnormal_hematopoietic_system1.30686295
57MP0004133_heterotaxia1.30213475
58MP0001929_abnormal_gametogenesis1.28706141
59MP0004147_increased_porphyrin_level1.27803695
60MP0003195_calcinosis1.27528325
61MP0002019_abnormal_tumor_incidence1.26302875
62MP0002009_preneoplasia1.26156602
63MP0002653_abnormal_ependyma_morphology1.24916028
64MP0001529_abnormal_vocalization1.22094916
65MP0002111_abnormal_tail_morphology1.21220130
66MP0000371_diluted_coat_color1.18148073
67MP0004264_abnormal_extraembryonic_tissu1.17457768
68MP0005174_abnormal_tail_pigmentation1.17334570
69MP0002282_abnormal_trachea_morphology1.14832669
70MP0002736_abnormal_nociception_after1.14636277
71MP0000313_abnormal_cell_death1.14013314
72MP0002095_abnormal_skin_pigmentation1.10938767
73MP0002160_abnormal_reproductive_system1.10126228
74MP0003453_abnormal_keratinocyte_physiol1.09406337
75MP0000537_abnormal_urethra_morphology1.07415226
76MP0000653_abnormal_sex_gland1.06526506
77MP0005023_abnormal_wound_healing1.05968300
78MP0005389_reproductive_system_phenotype1.05967746
79MP0000427_abnormal_hair_cycle1.04027697
80MP0001919_abnormal_reproductive_system1.03358493
81MP0002837_dystrophic_cardiac_calcinosis0.99724172
82MP0005379_endocrine/exocrine_gland_phen0.98818963
83MP0005253_abnormal_eye_physiology0.98630372
84MP0002269_muscular_atrophy0.98223653
85MP0001119_abnormal_female_reproductive0.98018878
86MP0001764_abnormal_homeostasis0.96562291
87MP0001915_intracranial_hemorrhage0.96546279
88MP0008789_abnormal_olfactory_epithelium0.94515099
89MP0002249_abnormal_larynx_morphology0.93504622
90MP0005395_other_phenotype0.92497531
91MP0003718_maternal_effect0.92140578
92MP0005367_renal/urinary_system_phenotyp0.91256798
93MP0000516_abnormal_urinary_system0.91256798
94MP0009703_decreased_birth_body0.88706414
95MP0003935_abnormal_craniofacial_develop0.88573230
96MP0004185_abnormal_adipocyte_glucose0.87674336
97MP0005408_hypopigmentation0.87149598
98MP0000432_abnormal_head_morphology0.86958831
99MP0003221_abnormal_cardiomyocyte_apopto0.85902273
100MP0002092_abnormal_eye_morphology0.85411449
101MP0002697_abnormal_eye_size0.83175153
102MP0003941_abnormal_skin_development0.82932916
103MP0003136_yellow_coat_color0.82869949
104MP0008872_abnormal_physiological_respon0.82633624
105MP0002877_abnormal_melanocyte_morpholog0.82439694
106MP0000647_abnormal_sebaceous_gland0.81789376
107MP0000733_abnormal_muscle_development0.81680577
108MP0002277_abnormal_respiratory_mucosa0.80219647
109MP0000428_abnormal_craniofacial_morphol0.79725638
110MP0003283_abnormal_digestive_organ0.78626259
111MP0003755_abnormal_palate_morphology0.78408093
112MP0002075_abnormal_coat/hair_pigmentati0.78123776
113MP0001986_abnormal_taste_sensitivity0.78034826
114MP0006072_abnormal_retinal_apoptosis0.77331285
115MP0000569_abnormal_digit_pigmentation0.77139917
116MP0000015_abnormal_ear_pigmentation0.75713900
117MP0005084_abnormal_gallbladder_morpholo0.75394373
118MP0005551_abnormal_eye_electrophysiolog0.75269730
119MP0004808_abnormal_hematopoietic_stem0.74950820
120MP0005266_abnormal_metabolism0.74534632
121MP0001145_abnormal_male_reproductive0.74017535
122MP0003698_abnormal_male_reproductive0.73676129
123MP0001661_extended_life_span0.73176353
124MP0002138_abnormal_hepatobiliary_system0.71806172
125MP0009333_abnormal_splenocyte_physiolog0.71632106
126MP0002925_abnormal_cardiovascular_devel0.70575753
127MP0002932_abnormal_joint_morphology0.70345162
128MP0010630_abnormal_cardiac_muscle0.69916172
129MP0000703_abnormal_thymus_morphology0.69171721
130MP0008995_early_reproductive_senescence0.68553811
131MP0001324_abnormal_eye_pigmentation0.68242223
132MP0002114_abnormal_axial_skeleton0.68000246
133MP0003937_abnormal_limbs/digits/tail_de0.67898696
134MP0005645_abnormal_hypothalamus_physiol0.67730332
135MP0005332_abnormal_amino_acid0.67400557
136MP0001849_ear_inflammation0.66839295
137MP0005671_abnormal_response_to0.65802947
138MP0000477_abnormal_intestine_morphology0.65252244
139MP0002210_abnormal_sex_determination0.65148661
140MP0001286_abnormal_eye_development0.63909264
141MP0003828_pulmonary_edema0.62963203
142MP0009672_abnormal_birth_weight0.62855587
143MP0005621_abnormal_cell_physiology0.62661836
144MP0000266_abnormal_heart_morphology0.61991849
145MP0005501_abnormal_skin_physiology0.61767591
146MP0005410_abnormal_fertilization0.61673247
147MP0003172_abnormal_lysosome_physiology0.60771464
148MP0010234_abnormal_vibrissa_follicle0.60309853
149MP0000689_abnormal_spleen_morphology0.60184422
150MP0008770_decreased_survivor_rate0.59848479
151MP0002751_abnormal_autonomic_nervous0.58500522
152MP0002060_abnormal_skin_morphology0.58286669
153MP0003699_abnormal_female_reproductive0.58053735
154MP0001853_heart_inflammation0.55643912
155MP0002233_abnormal_nose_morphology0.55526620
156MP0003121_genomic_imprinting0.54470955

Predicted human phenotypes

RankGene SetZ-score
1Facial hemangioma (HP:0000329)4.27153237
2Rib fusion (HP:0000902)3.82073490
3Abnormality of the labia minora (HP:0012880)3.60680498
4Ependymoma (HP:0002888)3.51058709
5Selective tooth agenesis (HP:0001592)3.48463030
6Abnormality of the astrocytes (HP:0100707)3.37245686
7Astrocytoma (HP:0009592)3.37245686
8Hypochromic microcytic anemia (HP:0004840)3.36856120
9Ulnar bowing (HP:0003031)3.33096949
10Short humerus (HP:0005792)3.31787078
11Volvulus (HP:0002580)3.31189451
12Aplasia/hypoplasia of the humerus (HP:0006507)3.29861615
13Abnormality of the preputium (HP:0100587)3.15789113
14Rectovaginal fistula (HP:0000143)3.15295702
15Rectal fistula (HP:0100590)3.15295702
16Meckel diverticulum (HP:0002245)3.14990518
17Poikiloderma (HP:0001029)3.09499102
18Basal cell carcinoma (HP:0002671)3.06614467
19Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.06396135
20Absent radius (HP:0003974)3.03733020
21Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.03089437
22Abnormality of alanine metabolism (HP:0010916)3.03089437
23Hyperalaninemia (HP:0003348)3.03089437
24Increased CSF lactate (HP:0002490)3.00599094
25Acute necrotizing encephalopathy (HP:0006965)2.91939646
26Neoplasm of the oral cavity (HP:0100649)2.87508886
27Increased hepatocellular lipid droplets (HP:0006565)2.87507835
28Patellar aplasia (HP:0006443)2.87467538
29Intestinal fistula (HP:0100819)2.87235288
30Annular pancreas (HP:0001734)2.83801253
31Aplasia involving forearm bones (HP:0009822)2.81911239
32Absent forearm bone (HP:0003953)2.81911239
33Pustule (HP:0200039)2.79296865
34Vertebral hypoplasia (HP:0008417)2.76375062
35Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.76375062
36Vaginal fistula (HP:0004320)2.76180474
37Absent thumb (HP:0009777)2.75653335
38Lipid accumulation in hepatocytes (HP:0006561)2.75534605
39Squamous cell carcinoma (HP:0002860)2.75101393
40Mitochondrial inheritance (HP:0001427)2.74679019
41Glioma (HP:0009733)2.72329642
42Type I transferrin isoform profile (HP:0003642)2.71061903
43Rhabdomyosarcoma (HP:0002859)2.68549137
44Increased serum lactate (HP:0002151)2.67112142
45Aplasia/Hypoplasia of the patella (HP:0006498)2.65166230
46Colon cancer (HP:0003003)2.63518698
47Acute encephalopathy (HP:0006846)2.62584405
48Abnormal mitochondria in muscle tissue (HP:0008316)2.62487330
49Medulloblastoma (HP:0002885)2.61737399
50Abnormality of the pons (HP:0007361)2.59579276
51Orthostatic hypotension (HP:0001278)2.58553906
523-Methylglutaconic aciduria (HP:0003535)2.56919904
53Hepatocellular necrosis (HP:0001404)2.55091868
54Molar tooth sign on MRI (HP:0002419)2.53946280
55Abnormality of midbrain morphology (HP:0002418)2.53946280
56Turricephaly (HP:0000262)2.51360792
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.50404573
58Abnormal protein N-linked glycosylation (HP:0012347)2.50404573
59Abnormal protein glycosylation (HP:0012346)2.50404573
60Abnormal glycosylation (HP:0012345)2.50404573
61Abnormality of methionine metabolism (HP:0010901)2.49598004
62Small intestinal stenosis (HP:0012848)2.47195040
63Duodenal stenosis (HP:0100867)2.47195040
64Pancreatic cysts (HP:0001737)2.44862381
65Hypoplasia of the pons (HP:0012110)2.43367370
66Alopecia of scalp (HP:0002293)2.39405020
67Sloping forehead (HP:0000340)2.38223196
68Progressive macrocephaly (HP:0004481)2.37905502
69Reticulocytopenia (HP:0001896)2.36823723
70Birth length less than 3rd percentile (HP:0003561)2.33657855
71Concave nail (HP:0001598)2.33612954
72Missing ribs (HP:0000921)2.33096328
73Agnosia (HP:0010524)2.32614327
74Cerebral edema (HP:0002181)2.31843223
75Tongue fasciculations (HP:0001308)2.31445804
76Hepatic necrosis (HP:0002605)2.27510831
77Premature graying of hair (HP:0002216)2.26515037
78Abnormality of aspartate family amino acid metabolism (HP:0010899)2.24810251
79Pancreatic fibrosis (HP:0100732)2.24633669
80Cerebral aneurysm (HP:0004944)2.23577804
81Abnormality of the ileum (HP:0001549)2.22045966
82Metaphyseal cupping (HP:0003021)2.21616793
83Muscle fibrillation (HP:0010546)2.19094459
84Abnormal number of incisors (HP:0011064)2.18817484
85Deviation of the thumb (HP:0009603)2.18772816
86Lactic acidosis (HP:0003128)2.18362503
87Abnormal lung lobation (HP:0002101)2.17984861
88Spinal muscular atrophy (HP:0007269)2.17343402
89Clubbing of toes (HP:0100760)2.17124485
90Abnormal hemoglobin (HP:0011902)2.13399814
91Proximal placement of thumb (HP:0009623)2.12551835
92Impulsivity (HP:0100710)2.09192769
93Renal cortical cysts (HP:0000803)2.09083498
94Coronal craniosynostosis (HP:0004440)2.08939596
95Neoplasm of striated muscle (HP:0009728)2.08596771
96Congenital hip dislocation (HP:0001374)2.07908852
97Broad alveolar ridges (HP:0000187)2.07694180
98Combined immunodeficiency (HP:0005387)2.07540059
99Abnormality of the duodenum (HP:0002246)2.07267032
100Intestinal atresia (HP:0011100)2.06912709
101Horseshoe kidney (HP:0000085)2.06616953
102Chromsome breakage (HP:0040012)2.05599265
103Abnormality of the lower motor neuron (HP:0002366)2.04915310
104Abnormality of serum amino acid levels (HP:0003112)2.04806309
105Vertebral fusion (HP:0002948)2.04532020
106Increased serum pyruvate (HP:0003542)2.02432306
107Breast hypoplasia (HP:0003187)2.01309139
108Small hand (HP:0200055)2.01120736
109Medial flaring of the eyebrow (HP:0010747)2.00953297
110Methylmalonic acidemia (HP:0002912)1.98863006
111Ectopic kidney (HP:0000086)1.98059501
112Abnormality of cells of the erythroid lineage (HP:0012130)1.97999201
113Abnormal number of erythroid precursors (HP:0012131)1.97198214
114Degeneration of anterior horn cells (HP:0002398)1.96640552
115Abnormality of the anterior horn cell (HP:0006802)1.96640552
116Short chin (HP:0000331)1.96071379
117Abnormality of chromosome stability (HP:0003220)1.95567089
118Abnormality of the carotid arteries (HP:0005344)1.95400089
119Abnormality of the renal cortex (HP:0011035)1.94880330
120Oral leukoplakia (HP:0002745)1.94145306
121Short thumb (HP:0009778)1.93620448
122Prominent nose (HP:0000448)1.93312337
123Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.92621568
124Short 1st metacarpal (HP:0010034)1.92621568
125Broad thumb (HP:0011304)1.92586466
126Homocystinuria (HP:0002156)1.92454949
127Abnormality of homocysteine metabolism (HP:0010919)1.92454949
128Heterotopia (HP:0002282)1.92143331
129IgA deficiency (HP:0002720)1.91687723
130Abnormality of the renal collecting system (HP:0004742)1.91403074
131Chromosomal breakage induced by crosslinking agents (HP:0003221)1.91210466
132Aplastic anemia (HP:0001915)1.90251391
133Cafe-au-lait spot (HP:0000957)1.89458894
134Severe combined immunodeficiency (HP:0004430)1.89250142
135Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.88349969
136Short 4th metacarpal (HP:0010044)1.88349969
137Nephronophthisis (HP:0000090)1.86763801
138Pancreatic islet-cell hyperplasia (HP:0004510)1.86720131
139Duplicated collecting system (HP:0000081)1.85896073
140Bowed forearm bones (HP:0003956)1.85144720
141Bowing of the arm (HP:0006488)1.85144720
142Neoplasm of the colon (HP:0100273)1.84596000
143Myelodysplasia (HP:0002863)1.83493833
144Spastic diplegia (HP:0001264)1.83466795
145Pendular nystagmus (HP:0012043)1.83388153
146Abnormality of the calcaneus (HP:0008364)1.83387045
147Abnormality of glycolysis (HP:0004366)1.82702911
148Hypotelorism (HP:0000601)1.82349239
149Increased IgM level (HP:0003496)1.81785256
150Biliary tract neoplasm (HP:0100574)1.80674193
151Pancytopenia (HP:0001876)1.79949642
152Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.79366086
153Macrocytic anemia (HP:0001972)1.79142848
154Microvesicular hepatic steatosis (HP:0001414)1.78851452
155Triphalangeal thumb (HP:0001199)1.78833702
156Cutaneous melanoma (HP:0012056)1.78654352
157Carpal bone hypoplasia (HP:0001498)1.78467346
158Reduced antithrombin III activity (HP:0001976)1.78043744
159Short 5th finger (HP:0009237)1.77220299
160Esophageal atresia (HP:0002032)1.76739677
161Cerebral hypomyelination (HP:0006808)1.76527568
162Multiple enchondromatosis (HP:0005701)1.76050010
163Hemivertebrae (HP:0002937)1.75635323
164Gastrointestinal atresia (HP:0002589)1.75564997
165Gastrointestinal carcinoma (HP:0002672)1.74726369
166Malignant gastrointestinal tract tumors (HP:0006749)1.74726369
167Hypochromic anemia (HP:0001931)1.73852373
168Abnormality of male internal genitalia (HP:0000022)1.73449047
169Pseudobulbar signs (HP:0002200)1.73299115
170Renal Fanconi syndrome (HP:0001994)1.72953888
171Aplasia/Hypoplasia of the uvula (HP:0010293)1.72712364
172Supernumerary spleens (HP:0009799)1.71368788
173Progressive inability to walk (HP:0002505)1.71314629
174Premature ovarian failure (HP:0008209)1.71230076
175CNS demyelination (HP:0007305)1.70919775
176Dysautonomia (HP:0002459)1.70797367
177Bile duct proliferation (HP:0001408)1.70244304
178Abnormal biliary tract physiology (HP:0012439)1.70244304
179Methylmalonic aciduria (HP:0012120)1.69989629
180Bone marrow hypocellularity (HP:0005528)1.69722324
181Abnormality of sulfur amino acid metabolism (HP:0004339)1.68368837
182Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.67981022
183Decreased activity of mitochondrial respiratory chain (HP:0008972)1.67981022
184Respiratory difficulties (HP:0002880)1.67881286

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK3.99177326
2DDR23.37222767
3CDC73.10726728
4ZAK3.06644676
5BMPR1B2.75793646
6MAP3K62.59499605
7CDK122.50550768
8WEE12.31577709
9NEK12.29804548
10MST42.29175069
11VRK22.26785080
12NEK22.16717251
13PBK2.11924220
14CDK72.07478254
15NUAK12.05549600
16FRK1.98263970
17LATS11.97800838
18STK161.91825227
19BUB11.88232090
20MAP3K111.86156498
21MAP3K101.80458255
22PDGFRA1.80111169
23BMX1.79080869
24TYRO31.76424296
25MAPK151.75750974
26CDK61.73092890
27PLK11.72541481
28PINK11.72439068
29RPS6KB21.67028734
30FGR1.66188780
31PDK21.63468884
32MATK1.61497451
33EEF2K1.60643342
34TTK1.60287760
35SCYL21.58669481
36VRK11.57772854
37TAF11.54324878
38CHEK21.51885278
39PIM11.47876854
40BCKDK1.45208604
41PKN21.44905360
42ATR1.43681623
43TNIK1.43222745
44LATS21.37886645
45SRPK11.35237934
46TRIM281.33784361
47MAP4K21.32845856
48CSK1.31149269
49CDK41.30675361
50STK101.25063871
51EPHA21.23344600
52WNK31.23298906
53AURKB1.21681935
54YES11.20926294
55DAPK11.19531319
56TRPM71.18202134
57ALK1.17590942
58STK31.14880020
59BRSK21.14606981
60CHEK11.13532291
61TSSK61.13102330
62MTOR1.13083067
63TRIB31.10490042
64DYRK1B1.08067137
65PLK21.07567492
66PASK1.04629514
67MAP3K81.03660754
68GRK11.02688547
69DYRK31.00495257
70AKT31.00088528
71CCNB10.99978850
72TAOK30.99039645
73CLK10.98871368
74EIF2AK10.98474923
75NME10.97740565
76PLK30.97627476
77CDK20.97060197
78PIM20.96423242
79EIF2AK20.95158545
80ATM0.94308625
81ADRBK20.93653345
82FLT30.92215804
83TAOK20.87662043
84PNCK0.84536670
85WNK40.84456870
86CDK80.84150434
87MAPK110.83788880
88UHMK10.80899071
89PRKD20.80794573
90RPS6KC10.80560962
91RPS6KL10.80560962
92AURKA0.79295033
93GSK3A0.77978392
94STK38L0.75697398
95ERBB40.74703144
96TESK20.73766023
97PLK40.73415083
98TXK0.73146872
99ACVR1B0.72777279
100MAP3K40.72627617
101NME20.71931438
102TLK10.71381359
103MKNK10.70059415
104RPS6KA60.69206843
105RPS6KA40.68935006
106TTN0.68903808
107PAK40.68657158
108OXSR10.66611322
109CDK10.65762296
110TEC0.63340476
111EIF2AK30.62295851
112STK40.61603678
113PAK20.57297134
114MAPK130.56381564
115RPS6KA10.55858248
116PRKCI0.55226295
117TGFBR10.55136013
118FGFR10.54948821
119CSNK2A20.54306039
120CDC42BPA0.52794524
121CSNK1G10.52600390
122CSNK2A10.49197159
123PRKAA10.46405107
124MAPK140.46339781
125BRD40.46338173
126MKNK20.46183673
127RPS6KB10.44712521
128BRSK10.44200980
129DYRK20.43775595
130BCR0.43597913
131MAPK10.42832847
132ERBB30.42670440
133STK390.42014205
134PRKDC0.40018022
135PDGFRB0.39599435
136CSNK1E0.39329012
137EGFR0.38546382
138IRAK40.38001390
139AKT20.35315118
140INSRR0.35297970
141MELK0.35267486
142RPS6KA50.34929740
143CSNK1G30.34006933
144IRAK10.33898210
145STK240.33147564
146MAP2K70.33093677
147BRAF0.31614172
148CSNK1G20.31083405
149KIT0.29540278
150MAP3K120.27322483
151CDK30.26319171

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034304.60550553
2DNA replication_Homo sapiens_hsa030304.36971329
3Base excision repair_Homo sapiens_hsa034103.56067973
4* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.30891001
5RNA transport_Homo sapiens_hsa030133.12234559
6Spliceosome_Homo sapiens_hsa030402.77532503
7One carbon pool by folate_Homo sapiens_hsa006702.74218899
8Nucleotide excision repair_Homo sapiens_hsa034202.58837946
9Cell cycle_Homo sapiens_hsa041102.44008675
10Protein export_Homo sapiens_hsa030602.37423683
11Fatty acid biosynthesis_Homo sapiens_hsa000612.34342842
12Homologous recombination_Homo sapiens_hsa034402.29888959
13mRNA surveillance pathway_Homo sapiens_hsa030152.17014437
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.03601574
15Oxidative phosphorylation_Homo sapiens_hsa001902.02255949
16Fanconi anemia pathway_Homo sapiens_hsa034601.93102736
17Parkinsons disease_Homo sapiens_hsa050121.83245087
18p53 signaling pathway_Homo sapiens_hsa041151.78015289
19Biosynthesis of amino acids_Homo sapiens_hsa012301.66809934
20mTOR signaling pathway_Homo sapiens_hsa041501.50392277
212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.47264638
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.43990193
23Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.42267437
24Propanoate metabolism_Homo sapiens_hsa006401.39698657
25Purine metabolism_Homo sapiens_hsa002301.34248885
26Huntingtons disease_Homo sapiens_hsa050161.33656641
27Hippo signaling pathway_Homo sapiens_hsa043901.32959623
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.32371318
29RNA degradation_Homo sapiens_hsa030181.30758467
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.28838295
31Systemic lupus erythematosus_Homo sapiens_hsa053221.28342329
32Viral carcinogenesis_Homo sapiens_hsa052031.26882853
33Adherens junction_Homo sapiens_hsa045201.26325172
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20417181
35RNA polymerase_Homo sapiens_hsa030201.19393728
36MicroRNAs in cancer_Homo sapiens_hsa052061.18374297
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.15214947
38Non-homologous end-joining_Homo sapiens_hsa034501.14301626
39Lysine degradation_Homo sapiens_hsa003101.14004248
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.13527062
41Selenocompound metabolism_Homo sapiens_hsa004501.10450617
42Notch signaling pathway_Homo sapiens_hsa043301.08843466
43TGF-beta signaling pathway_Homo sapiens_hsa043501.04709223
44Pyrimidine metabolism_Homo sapiens_hsa002401.03140168
45Transcriptional misregulation in cancer_Homo sapiens_hsa052021.00690753
46Pyruvate metabolism_Homo sapiens_hsa006201.00413800
47Steroid biosynthesis_Homo sapiens_hsa001000.97256982
48Proteasome_Homo sapiens_hsa030500.97202632
49Bladder cancer_Homo sapiens_hsa052190.95731911
50Alzheimers disease_Homo sapiens_hsa050100.95056238
51Oocyte meiosis_Homo sapiens_hsa041140.93619851
52Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92760495
53Sulfur metabolism_Homo sapiens_hsa009200.92133028
54Folate biosynthesis_Homo sapiens_hsa007900.91731199
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91687199
56Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91250072
57Hedgehog signaling pathway_Homo sapiens_hsa043400.90261249
58Small cell lung cancer_Homo sapiens_hsa052220.88443319
59Colorectal cancer_Homo sapiens_hsa052100.86905885
60Arginine and proline metabolism_Homo sapiens_hsa003300.86811711
61Ribosome_Homo sapiens_hsa030100.86464328
62Epstein-Barr virus infection_Homo sapiens_hsa051690.85059424
63Chronic myeloid leukemia_Homo sapiens_hsa052200.84752773
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.83981024
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.83078429
66Basal cell carcinoma_Homo sapiens_hsa052170.82081402
67Fatty acid elongation_Homo sapiens_hsa000620.81858881
68Butanoate metabolism_Homo sapiens_hsa006500.81664948
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.80550739
70Basal transcription factors_Homo sapiens_hsa030220.79877413
71HTLV-I infection_Homo sapiens_hsa051660.78940331
72Herpes simplex infection_Homo sapiens_hsa051680.76601090
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75942062
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.73111277
75Legionellosis_Homo sapiens_hsa051340.71929769
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.71018051
77Thyroid cancer_Homo sapiens_hsa052160.70290209
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.69134506
79Arginine biosynthesis_Homo sapiens_hsa002200.68728488
80Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68599557
81Fructose and mannose metabolism_Homo sapiens_hsa000510.68062914
82Viral myocarditis_Homo sapiens_hsa054160.67237039
83Nitrogen metabolism_Homo sapiens_hsa009100.65824214
84Shigellosis_Homo sapiens_hsa051310.64966427
85Asthma_Homo sapiens_hsa053100.64843662
86Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63912281
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63531956
88Metabolic pathways_Homo sapiens_hsa011000.60641424
89Antigen processing and presentation_Homo sapiens_hsa046120.60543582
90Carbon metabolism_Homo sapiens_hsa012000.60362469
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.60121916
92Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60080888
93Peroxisome_Homo sapiens_hsa041460.59153354
94Phototransduction_Homo sapiens_hsa047440.57742365
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56113865
96Regulation of autophagy_Homo sapiens_hsa041400.55838918
97Tryptophan metabolism_Homo sapiens_hsa003800.55334977
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.55167204
99Glutathione metabolism_Homo sapiens_hsa004800.53846663
100Proteoglycans in cancer_Homo sapiens_hsa052050.53675797
101Sulfur relay system_Homo sapiens_hsa041220.53449978
102Wnt signaling pathway_Homo sapiens_hsa043100.52494174
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.50820136
104Tight junction_Homo sapiens_hsa045300.50568763
105Endometrial cancer_Homo sapiens_hsa052130.50154814
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.47391716
107Circadian rhythm_Homo sapiens_hsa047100.46991441
108Pentose phosphate pathway_Homo sapiens_hsa000300.46334479
109Hepatitis B_Homo sapiens_hsa051610.45615692
110N-Glycan biosynthesis_Homo sapiens_hsa005100.43992801
111Acute myeloid leukemia_Homo sapiens_hsa052210.43596886
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.43452060
113Galactose metabolism_Homo sapiens_hsa000520.42630124
114Fatty acid metabolism_Homo sapiens_hsa012120.42442248
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41284927
116AMPK signaling pathway_Homo sapiens_hsa041520.41080834
117Prostate cancer_Homo sapiens_hsa052150.40241591
118Apoptosis_Homo sapiens_hsa042100.39968835
119Non-small cell lung cancer_Homo sapiens_hsa052230.38921882
120Insulin signaling pathway_Homo sapiens_hsa049100.38798039
121HIF-1 signaling pathway_Homo sapiens_hsa040660.38256792
122VEGF signaling pathway_Homo sapiens_hsa043700.37902420
123Primary immunodeficiency_Homo sapiens_hsa053400.37599940
124Focal adhesion_Homo sapiens_hsa045100.37315905
125Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36817732
126SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35909294
127Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35446638
128Pancreatic cancer_Homo sapiens_hsa052120.35350944
129Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34822353
130Caffeine metabolism_Homo sapiens_hsa002320.33231232
131Vitamin B6 metabolism_Homo sapiens_hsa007500.32010022
132Graft-versus-host disease_Homo sapiens_hsa053320.31415891
133Pathways in cancer_Homo sapiens_hsa052000.30772362
134Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.30457986
135Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30378176
136Autoimmune thyroid disease_Homo sapiens_hsa053200.29578930
137Type I diabetes mellitus_Homo sapiens_hsa049400.28741346
138Primary bile acid biosynthesis_Homo sapiens_hsa001200.28672827
139Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28386906
140Ether lipid metabolism_Homo sapiens_hsa005650.28095864
141Allograft rejection_Homo sapiens_hsa053300.26672174
142Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.24645807
143Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.22802299
144Retinol metabolism_Homo sapiens_hsa008300.20188024
145Cardiac muscle contraction_Homo sapiens_hsa042600.18548383
146Olfactory transduction_Homo sapiens_hsa047400.16832417
147Steroid hormone biosynthesis_Homo sapiens_hsa001400.14984271
148Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.14751937
149Fatty acid degradation_Homo sapiens_hsa000710.13714771

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