UTP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of translational termination (GO:0006449)5.10379059
2mitotic metaphase plate congression (GO:0007080)4.57619667
3formation of translation preinitiation complex (GO:0001731)4.53691890
4protein localization to kinetochore (GO:0034501)4.34182277
5ribosomal small subunit assembly (GO:0000028)4.31444297
6maturation of SSU-rRNA (GO:0030490)4.24935707
7DNA replication checkpoint (GO:0000076)4.09505380
8DNA strand elongation involved in DNA replication (GO:0006271)4.02611754
9metaphase plate congression (GO:0051310)3.88932579
10DNA unwinding involved in DNA replication (GO:0006268)3.88252056
11ribosome biogenesis (GO:0042254)3.86510604
12nucleobase biosynthetic process (GO:0046112)3.81363131
13DNA strand elongation (GO:0022616)3.80764582
14ribosomal large subunit biogenesis (GO:0042273)3.78093376
15DNA replication initiation (GO:0006270)3.77924800
16protein localization to chromosome, centromeric region (GO:0071459)3.75445085
17ribonucleoprotein complex biogenesis (GO:0022613)3.75443409
18purine nucleobase biosynthetic process (GO:0009113)3.74625540
19viral transcription (GO:0019083)3.74529204
20translational termination (GO:0006415)3.73493329
21kinetochore organization (GO:0051383)3.68106628
22DNA deamination (GO:0045006)3.65294960
23telomere maintenance via semi-conservative replication (GO:0032201)3.64729955
24mitotic nuclear envelope disassembly (GO:0007077)3.64574178
25regulation of spindle organization (GO:0090224)3.64069733
26ribosomal small subunit biogenesis (GO:0042274)3.61789690
27histone H2B ubiquitination (GO:0033523)3.61278681
28ribosome assembly (GO:0042255)3.60473131
29regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.59772564
30attachment of spindle microtubules to kinetochore (GO:0008608)3.57006625
31mitotic sister chromatid cohesion (GO:0007064)3.56838438
32regulation of RNA export from nucleus (GO:0046831)3.55420127
33establishment of chromosome localization (GO:0051303)3.50853180
34CENP-A containing nucleosome assembly (GO:0034080)3.50745246
35translational initiation (GO:0006413)3.48404029
36chromatin remodeling at centromere (GO:0031055)3.42254401
37establishment of integrated proviral latency (GO:0075713)3.42065272
38telomere maintenance via recombination (GO:0000722)3.41999361
39nuclear pore organization (GO:0006999)3.38732532
40mitotic sister chromatid segregation (GO:0000070)3.37543219
41translational elongation (GO:0006414)3.34866901
42membrane disassembly (GO:0030397)3.33829696
43nuclear envelope disassembly (GO:0051081)3.33829696
44kinetochore assembly (GO:0051382)3.33592080
45folic acid-containing compound biosynthetic process (GO:0009396)3.31080295
46mitotic recombination (GO:0006312)3.29932892
47spliceosomal snRNP assembly (GO:0000387)3.29800993
48rRNA processing (GO:0006364)3.28362616
49regulation of nucleobase-containing compound transport (GO:0032239)3.25741961
50mitotic chromosome condensation (GO:0007076)3.24205651
51nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.24147669
52regulation of translational fidelity (GO:0006450)3.23820649
53DNA replication-independent nucleosome organization (GO:0034724)3.23272863
54DNA replication-independent nucleosome assembly (GO:0006336)3.23272863
55heterochromatin organization (GO:0070828)3.22972252
56rRNA metabolic process (GO:0016072)3.17943850
57negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.17144183
58IMP biosynthetic process (GO:0006188)3.17070788
59telomere maintenance via telomere lengthening (GO:0010833)3.14496758
60regulation of mitotic spindle organization (GO:0060236)3.14245352
61SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.12845790
62anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.08092120
63positive regulation of chromosome segregation (GO:0051984)3.07641139
64DNA replication-dependent nucleosome assembly (GO:0006335)3.06865518
65DNA replication-dependent nucleosome organization (GO:0034723)3.06865518
66negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.05276737
67cotranslational protein targeting to membrane (GO:0006613)3.04016306
68regulation of vitamin D biosynthetic process (GO:0060556)3.03601506
69protein targeting to ER (GO:0045047)3.02515432
70regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.01721396
71spindle checkpoint (GO:0031577)3.00490947
72sister chromatid segregation (GO:0000819)2.99930170
73nuclear pore complex assembly (GO:0051292)2.98851596
74nucleotide-excision repair, DNA gap filling (GO:0006297)2.98523008
75positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.96631145
76cellular protein complex disassembly (GO:0043624)2.94562678
77viral life cycle (GO:0019058)2.92557690
78regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.92259426
79proteasome assembly (GO:0043248)2.90848724
80pore complex assembly (GO:0046931)2.90790573
81negative regulation of chromosome segregation (GO:0051985)2.90368176
82histone exchange (GO:0043486)2.89373617
83pseudouridine synthesis (GO:0001522)2.88785735
84regulation of mitotic metaphase/anaphase transition (GO:0030071)2.88619673
85negative regulation of mitotic sister chromatid separation (GO:2000816)2.87980573
86negative regulation of mitotic sister chromatid segregation (GO:0033048)2.87980573
87negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.87980573
88negative regulation of sister chromatid segregation (GO:0033046)2.87980573
89IMP metabolic process (GO:0046040)2.87618539
90cellular protein complex localization (GO:0034629)2.87457087
91regulation of nuclear cell cycle DNA replication (GO:0033262)2.87202506
92spindle assembly checkpoint (GO:0071173)2.86828448
93establishment of protein localization to endoplasmic reticulum (GO:0072599)2.85752710
94termination of RNA polymerase II transcription (GO:0006369)2.85276596
95transcription-coupled nucleotide-excision repair (GO:0006283)2.85266443
96positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.84683306
97protein maturation by protein folding (GO:0022417)2.83978892
98mitotic spindle assembly checkpoint (GO:0007094)2.83468770
99spliceosomal complex assembly (GO:0000245)2.83128590
100regulation of double-strand break repair via homologous recombination (GO:0010569)2.82683138
101regulation of chromosome segregation (GO:0051983)2.82658553
102RNA splicing, via transesterification reactions (GO:0000375)2.82296946
103regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.81778098
104rRNA modification (GO:0000154)2.80795793
105protein localization to endoplasmic reticulum (GO:0070972)2.80485018
106mRNA cleavage (GO:0006379)2.79670350
107mitotic spindle checkpoint (GO:0071174)2.79667051
108negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.79145567
109nucleobase-containing small molecule interconversion (GO:0015949)2.79074795
110protein localization to chromosome (GO:0034502)2.78815786
111positive regulation of mitotic sister chromatid separation (GO:1901970)2.78780241
112positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.78780241
113positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.78780241
114regulation of centrosome cycle (GO:0046605)2.78662503
115transcription from mitochondrial promoter (GO:0006390)2.78324906
116negative regulation of ligase activity (GO:0051352)2.78306112
117negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78306112
118G1/S transition of mitotic cell cycle (GO:0000082)2.78069318
119regulation of transcription from RNA polymerase I promoter (GO:0006356)2.74598107
120translation (GO:0006412)2.74581020
121negative regulation of RNA splicing (GO:0033119)2.72343550
122DNA topological change (GO:0006265)2.71503322
123positive regulation of DNA-templated transcription, elongation (GO:0032786)2.68580667
124RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.66262287
125mRNA splicing, via spliceosome (GO:0000398)2.66262287
126negative regulation of mRNA processing (GO:0050686)2.66016855
127telomere maintenance via telomerase (GO:0007004)2.65035174
128RNA-dependent DNA replication (GO:0006278)2.62188230
129establishment of viral latency (GO:0019043)2.61504682
130cellular component biogenesis (GO:0044085)2.58148864
131protein complex localization (GO:0031503)2.58014534
132ER overload response (GO:0006983)2.57230270
133regulation of helicase activity (GO:0051095)2.55089935
134chromosome condensation (GO:0030261)2.55039081
135negative regulation of mRNA metabolic process (GO:1903312)2.54137855
136negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.53503797
137protein export from nucleus (GO:0006611)2.52065886
138N-terminal protein amino acid acetylation (GO:0006474)2.42360248
139ether lipid metabolic process (GO:0046485)2.41215521
140negative regulation of androgen receptor signaling pathway (GO:0060766)2.39926855
141mRNA stabilization (GO:0048255)2.38620791
142RNA stabilization (GO:0043489)2.38620791
143negative regulation of telomerase activity (GO:0051974)2.37282686
144regulation of translational initiation (GO:0006446)2.36744777
145regulation of histone H3-K27 methylation (GO:0061085)2.35786152
1463-UTR-mediated mRNA stabilization (GO:0070935)2.35602726
147DNA-templated transcription, termination (GO:0006353)2.35324044
148regulation of translation in response to stress (GO:0043555)2.34802077
149regulation of translational elongation (GO:0006448)2.34532515
150tetrahydrofolate metabolic process (GO:0046653)2.34131342
151nuclear-transcribed mRNA catabolic process (GO:0000956)2.30170232
152regulation of DNA endoreduplication (GO:0032875)2.28079175
153protein complex disassembly (GO:0043241)2.27744650

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.49978715
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.18910626
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.17519058
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.50374263
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.41871703
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.25163305
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.12518062
8TP63_17297297_ChIP-ChIP_HaCaT_Human2.95001448
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.94847316
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.94258601
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.94135475
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.76609912
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.76558422
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.74320553
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.68290184
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.67261778
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31123595
18XRN2_22483619_ChIP-Seq_HELA_Human2.26949291
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.24705897
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.24678585
21* VDR_23849224_ChIP-Seq_CD4+_Human2.24571909
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.21703411
23AR_21909140_ChIP-Seq_LNCAP_Human2.09834803
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.05219664
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97093581
26DCP1A_22483619_ChIP-Seq_HELA_Human1.96385810
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.96081618
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.95380174
29E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94705041
30* FOXP3_21729870_ChIP-Seq_TREG_Human1.91623762
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.86916104
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.86682141
33E2F1_21310950_ChIP-Seq_MCF-7_Human1.85682196
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84931066
35GABP_19822575_ChIP-Seq_HepG2_Human1.82026777
36TTF2_22483619_ChIP-Seq_HELA_Human1.79738827
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79186766
38ELK1_19687146_ChIP-ChIP_HELA_Human1.76558380
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68487446
40NANOG_18555785_ChIP-Seq_MESCs_Mouse1.67525728
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.66920045
42MYC_22102868_ChIP-Seq_BL_Human1.65155563
43SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.64322593
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64114960
45KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.63288432
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.58905699
47SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.58313962
48CIITA_25753668_ChIP-Seq_RAJI_Human1.55032016
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52654219
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.51804882
51* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50931607
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.50915431
53KDM5A_27292631_Chip-Seq_BREAST_Human1.49516665
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46345308
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45299616
56YY1_21170310_ChIP-Seq_MESCs_Mouse1.41341620
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.35659152
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.31245391
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28739696
60KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28587395
61SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.28489407
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.28390607
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25921800
64STAT3_1855785_ChIP-Seq_MESCs_Mouse1.25234798
65* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25130056
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.23988988
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22640852
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.22149747
69TFEB_21752829_ChIP-Seq_HELA_Human1.21984349
70TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21822367
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20471384
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.19266387
73CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18816838
74ZNF263_19887448_ChIP-Seq_K562_Human1.18098839
75MYB_21317192_ChIP-Seq_ERMYB_Mouse1.18087874
76ERG_20887958_ChIP-Seq_HPC-7_Mouse1.16463379
77CHD1_26751641_Chip-Seq_LNCaP_Human1.15291237
78* SPI1_23547873_ChIP-Seq_NB4_Human1.14757176
79* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13399703
80MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09737060
81STAT6_21828071_ChIP-Seq_BEAS2B_Human1.09413989
82ATF3_27146783_Chip-Seq_COLON_Human1.07902128
83SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.07883077
84CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.07340579
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06913587
86CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06859565
87VDR_21846776_ChIP-Seq_THP-1_Human1.05582683
88DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05292140
89IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04899441
90TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03289011
91* ELK1_22589737_ChIP-Seq_MCF10A_Human1.01591341
92SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01163159
93TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00064274
94BRD4_27068464_Chip-Seq_AML-cells_Mouse0.99420030
95ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99023874
96KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98182638
97BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98072482
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97878229
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.97351995
100PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97199953
101ELK3_25401928_ChIP-Seq_HUVEC_Human0.95074410
102SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94365272
103FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.94263209
104* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93991683
105CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93904234
106MYC_18940864_ChIP-ChIP_HL60_Human0.93580677
107RBPJ_22232070_ChIP-Seq_NCS_Mouse0.92900988
108* ELF5_23300383_ChIP-Seq_T47D_Human0.92263498
109CLOCK_20551151_ChIP-Seq_293T_Human0.91163541
110NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.90638946
111CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90228808
112NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.90031406
113KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.87331098
114KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.87331098
115KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.87331098
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86889834
117EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.86472330
118OCT4_18692474_ChIP-Seq_MEFs_Mouse0.85081842
119IRF8_21731497_ChIP-ChIP_J774_Mouse0.84555758
120IRF8_22096565_ChIP-ChIP_GC-B_Human0.84406892
121HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84299170
122* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83787842
123* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.81140308
124* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.79129019
125NANOG_21062744_ChIP-ChIP_HESCs_Human0.79109276

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.25497203
2MP0004957_abnormal_blastocyst_morpholog4.22233778
3MP0010094_abnormal_chromosome_stability3.96672132
4MP0003111_abnormal_nucleus_morphology3.94877239
5MP0003077_abnormal_cell_cycle3.78727436
6MP0008057_abnormal_DNA_replication3.56546999
7MP0008058_abnormal_DNA_repair2.96379904
8MP0008007_abnormal_cellular_replicative2.77458676
9MP0010234_abnormal_vibrissa_follicle2.57613705
10MP0008932_abnormal_embryonic_tissue2.42105782
11MP0002796_impaired_skin_barrier2.27813338
12MP0001730_embryonic_growth_arrest2.21966660
13MP0002396_abnormal_hematopoietic_system2.19029526
14MP0010352_gastrointestinal_tract_polyps2.15295258
15MP0000350_abnormal_cell_proliferation2.13597906
16MP0002877_abnormal_melanocyte_morpholog2.13413405
17MP0005451_abnormal_body_composition2.08142792
18MP0010030_abnormal_orbit_morphology2.05423855
19MP0003123_paternal_imprinting2.02405046
20MP0000490_abnormal_crypts_of1.83629562
21MP0005501_abnormal_skin_physiology1.79273781
22MP0008877_abnormal_DNA_methylation1.78653828
23MP0001672_abnormal_embryogenesis/_devel1.78035515
24MP0005380_embryogenesis_phenotype1.78035515
25MP0009333_abnormal_splenocyte_physiolog1.67962487
26MP0003984_embryonic_growth_retardation1.67534734
27MP0010307_abnormal_tumor_latency1.67199195
28MP0002088_abnormal_embryonic_growth/wei1.64229289
29MP0003786_premature_aging1.63091529
30MP0001697_abnormal_embryo_size1.61109014
31MP0003453_abnormal_keratinocyte_physiol1.58570339
32MP0004808_abnormal_hematopoietic_stem1.55084837
33MP0005076_abnormal_cell_differentiation1.50305233
34MP0002019_abnormal_tumor_incidence1.48633871
35MP0000678_abnormal_parathyroid_gland1.45233113
36MP0002080_prenatal_lethality1.44854681
37MP0003763_abnormal_thymus_physiology1.43427472
38MP0000313_abnormal_cell_death1.41275283
39MP0002086_abnormal_extraembryonic_tissu1.40709258
40MP0002398_abnormal_bone_marrow1.34504386
41MP0002085_abnormal_embryonic_tissue1.33590391
42MP0004197_abnormal_fetal_growth/weight/1.31090660
43MP0003718_maternal_effect1.30126464
44MP0000703_abnormal_thymus_morphology1.28668164
45MP0001835_abnormal_antigen_presentation1.27746577
46MP0002060_abnormal_skin_morphology1.27470658
47MP0002084_abnormal_developmental_patter1.27137372
48MP0003567_abnormal_fetal_cardiomyocyte1.26039735
49MP0002722_abnormal_immune_system1.25465601
50MP0000858_altered_metastatic_potential1.25054530
51MP0001545_abnormal_hematopoietic_system1.24058431
52MP0005397_hematopoietic_system_phenotyp1.24058431
53MP0001293_anophthalmia1.22789353
54MP0001216_abnormal_epidermal_layer1.22234514
55MP0000689_abnormal_spleen_morphology1.21707284
56MP0005257_abnormal_intraocular_pressure1.21343005
57MP0003890_abnormal_embryonic-extraembry1.19359060
58MP0004185_abnormal_adipocyte_glucose1.18872142
59MP0003300_gastrointestinal_ulcer1.18066204
60MP0004947_skin_inflammation1.17678441
61MP0003091_abnormal_cell_migration1.15677696
62MP0001881_abnormal_mammary_gland1.14942415
63MP0004233_abnormal_muscle_weight1.14434761
64MP0009053_abnormal_anal_canal1.12629942
65MP0003303_peritoneal_inflammation1.09217822
66MP0003806_abnormal_nucleotide_metabolis1.07539978
67MP0009785_altered_susceptibility_to1.06297230
68MP0003436_decreased_susceptibility_to1.05216568
69MP0001800_abnormal_humoral_immune1.04911612
70MP0002429_abnormal_blood_cell1.03996747
71MP0005671_abnormal_response_to1.03647668
72MP0002163_abnormal_gland_morphology1.03526829
73MP0006292_abnormal_olfactory_placode1.01947425
74MP0001849_ear_inflammation1.01161798
75MP0000716_abnormal_immune_system1.01036699
76MP0002132_abnormal_respiratory_system1.00068286
77MP0000627_abnormal_mammary_gland0.99619322
78MP0003121_genomic_imprinting0.99363574
79MP0003186_abnormal_redox_activity0.99170297
80MP0005023_abnormal_wound_healing0.97014636
81MP0002452_abnormal_antigen_presenting0.96235563
82MP0002420_abnormal_adaptive_immunity0.92715721
83MP0001819_abnormal_immune_cell0.92567639
84MP0003448_altered_tumor_morphology0.90090185
85MP0000685_abnormal_immune_system0.88245384
86MP0002405_respiratory_system_inflammati0.87691032
87MP0006035_abnormal_mitochondrial_morpho0.87031233
88MP0002254_reproductive_system_inflammat0.86919793
89MP0003705_abnormal_hypodermis_morpholog0.85628537
90MP0002723_abnormal_immune_serum0.85562484
91MP0001853_heart_inflammation0.83015182
92MP0003950_abnormal_plasma_membrane0.81874674
93MP0003941_abnormal_skin_development0.81708949
94MP0003119_abnormal_digestive_system0.80404969
95MP0003315_abnormal_perineum_morphology0.79965423
96MP0001243_abnormal_dermal_layer0.78542446
97MP0005025_abnormal_response_to0.77660185
98MP0010155_abnormal_intestine_physiology0.77196012
99MP0005000_abnormal_immune_tolerance0.76488098
100MP0001727_abnormal_embryo_implantation0.75218462
101MP0003221_abnormal_cardiomyocyte_apopto0.74051453
102MP0009672_abnormal_birth_weight0.73511008
103MP0000477_abnormal_intestine_morphology0.73226773
104MP0005621_abnormal_cell_physiology0.72588660
105MP0002210_abnormal_sex_determination0.72221139
106MP0005384_cellular_phenotype0.72065400
107MP0002166_altered_tumor_susceptibility0.71515571
108MP0002006_tumorigenesis0.71493343
109MP0001542_abnormal_bone_strength0.71163475
110MP0009278_abnormal_bone_marrow0.70839000
111MP0000358_abnormal_cell_content/0.70621363
112MP0009379_abnormal_foot_pigmentation0.69478267
113MP0001119_abnormal_female_reproductive0.67699109
114MP0006054_spinal_hemorrhage0.66500493
115MP0001915_intracranial_hemorrhage0.66446115
116MP0003566_abnormal_cell_adhesion0.65258769
117MP0002111_abnormal_tail_morphology0.63664592
118MP0001145_abnormal_male_reproductive0.63151779
119MP0001286_abnormal_eye_development0.62778205
120MP0009703_decreased_birth_body0.60219432
121MP0004264_abnormal_extraembryonic_tissu0.59245400
122MP0002092_abnormal_eye_morphology0.58588133
123MP0005387_immune_system_phenotype0.54943767
124MP0001790_abnormal_immune_system0.54943767
125MP0002148_abnormal_hypersensitivity_rea0.54816361
126MP0000537_abnormal_urethra_morphology0.54212882
127MP0001845_abnormal_inflammatory_respons0.52703929

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.60087985
2Abnormality of cells of the erythroid lineage (HP:0012130)3.92293068
3Reticulocytopenia (HP:0001896)3.90925105
4Abnormality of the anterior horn cell (HP:0006802)3.74082820
5Degeneration of anterior horn cells (HP:0002398)3.74082820
6Abnormal number of erythroid precursors (HP:0012131)3.65374644
7Breast hypoplasia (HP:0003187)3.42283681
8Patellar aplasia (HP:0006443)3.31861222
9Progressive muscle weakness (HP:0003323)3.15325131
10Carpal bone hypoplasia (HP:0001498)3.14872996
11Aplasia/Hypoplasia of the patella (HP:0006498)3.08439129
12Chromsome breakage (HP:0040012)3.07839381
13Deep palmar crease (HP:0006191)3.04969546
14Progressive external ophthalmoplegia (HP:0000590)3.01934584
15Oral leukoplakia (HP:0002745)2.99125987
16Colon cancer (HP:0003003)2.92569916
17Agnosia (HP:0010524)2.91120102
18Impulsivity (HP:0100710)2.89959910
19B lymphocytopenia (HP:0010976)2.88879171
20Multiple enchondromatosis (HP:0005701)2.85479766
21Microvesicular hepatic steatosis (HP:0001414)2.85382996
22Macrocytic anemia (HP:0001972)2.80390033
23Absent thumb (HP:0009777)2.78019272
24Trismus (HP:0000211)2.77965537
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.76361256
26Congenital ichthyosiform erythroderma (HP:0007431)2.70814090
27Abnormality of chromosome stability (HP:0003220)2.68536904
28Abnormality of the preputium (HP:0100587)2.67988195
29Meckel diverticulum (HP:0002245)2.66311696
30Rough bone trabeculation (HP:0100670)2.61215931
31Pallor (HP:0000980)2.59851979
32Abnormality of the ileum (HP:0001549)2.55621195
33Abnormality of B cell number (HP:0010975)2.52353013
34Microretrognathia (HP:0000308)2.49836926
35Myelodysplasia (HP:0002863)2.48911690
36Gastrointestinal stroma tumor (HP:0100723)2.47432914
37Atrophy/Degeneration involving motor neurons (HP:0007373)2.46797066
38Selective tooth agenesis (HP:0001592)2.45631503
39Aplasia/Hypoplasia of the uvula (HP:0010293)2.44236711
40Pustule (HP:0200039)2.40163091
41Cleft eyelid (HP:0000625)2.39845855
42Abnormal lung lobation (HP:0002101)2.34663304
43Rhabdomyosarcoma (HP:0002859)2.33965225
44Recurrent viral infections (HP:0004429)2.33842827
45Glossoptosis (HP:0000162)2.33610510
46Absent radius (HP:0003974)2.33032049
47Medulloblastoma (HP:0002885)2.29412530
48Premature ovarian failure (HP:0008209)2.26039530
49Poor head control (HP:0002421)2.25259270
50Spastic diplegia (HP:0001264)2.24973823
51Small intestinal stenosis (HP:0012848)2.24615131
52Duodenal stenosis (HP:0100867)2.24615131
53Cellular immunodeficiency (HP:0005374)2.23773725
54Aplastic anemia (HP:0001915)2.21927642
55Ependymoma (HP:0002888)2.21035969
56Cerebral hypomyelination (HP:0006808)2.20937920
57Atresia of the external auditory canal (HP:0000413)2.19580178
58Osteolytic defects of the hand bones (HP:0009699)2.19564488
59Osteolytic defects of the phalanges of the hand (HP:0009771)2.19564488
60Embryonal renal neoplasm (HP:0011794)2.18826710
61Fragile skin (HP:0001030)2.17334859
62Hyperacusis (HP:0010780)2.16909576
63Combined immunodeficiency (HP:0005387)2.15036216
64Deviation of the thumb (HP:0009603)2.13360858
65Proximal placement of thumb (HP:0009623)2.12023763
66Abnormality of the distal phalanges of the toes (HP:0010182)2.11961392
67Abnormal number of incisors (HP:0011064)2.11393007
68Long palpebral fissure (HP:0000637)2.10145272
69Achilles tendon contracture (HP:0001771)2.09850810
70Absent forearm bone (HP:0003953)2.08462342
71Aplasia involving forearm bones (HP:0009822)2.08462342
72Cutaneous melanoma (HP:0012056)2.08225428
73Neoplasm of the pancreas (HP:0002894)2.08130447
74T lymphocytopenia (HP:0005403)2.07928415
75Tracheoesophageal fistula (HP:0002575)2.07792550
76Premature rupture of membranes (HP:0001788)2.07159396
77Spinal muscular atrophy (HP:0007269)2.04811253
78Triphalangeal thumb (HP:0001199)2.02813190
79Bone marrow hypocellularity (HP:0005528)2.02501354
80IgA deficiency (HP:0002720)2.02341822
81Poikiloderma (HP:0001029)2.01522045
82Squamous cell carcinoma (HP:0002860)2.01407858
83Basal cell carcinoma (HP:0002671)2.00965763
84Thrombocytosis (HP:0001894)2.00815554
85Insomnia (HP:0100785)2.00756117
86Premature graying of hair (HP:0002216)1.99714636
87Increased nuchal translucency (HP:0010880)1.99514016
88Abnormality of nail color (HP:0100643)1.99099160
89Ectopic kidney (HP:0000086)1.98754795
90Overriding aorta (HP:0002623)1.97435267
91Abnormality of T cell number (HP:0011839)1.96780020
92Secondary amenorrhea (HP:0000869)1.96191851
93Abnormal trabecular bone morphology (HP:0100671)1.95420525
9411 pairs of ribs (HP:0000878)1.95364768
95Horseshoe kidney (HP:0000085)1.95125912
96Lymphoma (HP:0002665)1.95066613
97Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.95019934
98Sparse scalp hair (HP:0002209)1.94083706
99Irregular epiphyses (HP:0010582)1.93443784
100Sloping forehead (HP:0000340)1.92639009
101Abnormality of T cells (HP:0002843)1.91569088
102Autoimmune hemolytic anemia (HP:0001890)1.90158591
103Aplasia/Hypoplasia of the sternum (HP:0006714)1.88671605
104Rib fusion (HP:0000902)1.87414468
105IgM deficiency (HP:0002850)1.85618322
106Abnormality of the duodenum (HP:0002246)1.85046260
107Abnormality of glycolipid metabolism (HP:0010969)1.84031895
108Abnormality of liposaccharide metabolism (HP:0010968)1.84031895
109Abnormality of glycosphingolipid metabolism (HP:0004343)1.84031895
110Oligodontia (HP:0000677)1.83040391
111Short middle phalanx of the 5th finger (HP:0004220)1.82872253
112Abnormality of the labia minora (HP:0012880)1.82437264
113Cellulitis (HP:0100658)1.82295696
114Hyperparathyroidism (HP:0000843)1.81216649
115Ridged nail (HP:0001807)1.81178719
116Supernumerary spleens (HP:0009799)1.80352311
117Sparse eyelashes (HP:0000653)1.79952246
118Blepharitis (HP:0000498)1.79107514
119Slender long bone (HP:0003100)1.78626765
120Spinal cord lesions (HP:0100561)1.77905974
121Syringomyelia (HP:0003396)1.77905974
122Septate vagina (HP:0001153)1.76416380
123Abnormality of the gastric mucosa (HP:0004295)1.75888719
124Progressive hearing impairment (HP:0001730)1.74525953
125Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74276401
126Tetraparesis (HP:0002273)1.73815224
127Asymmetry of the thorax (HP:0001555)1.73519347
128Severe combined immunodeficiency (HP:0004430)1.72836455
129Neoplasm of the colon (HP:0100273)1.72030470
130Facial hemangioma (HP:0000329)1.71620596
131Abnormality of pyrimidine metabolism (HP:0004353)1.71302601
132Sparse lateral eyebrow (HP:0005338)1.70592259
133Amaurosis fugax (HP:0100576)1.70535341
134Ankyloglossia (HP:0010296)1.69727022
135Thyroid-stimulating hormone excess (HP:0002925)1.69513989
136Atrophic scars (HP:0001075)1.69299971
137Onycholysis (HP:0001806)1.69075074
138Thoracic kyphosis (HP:0002942)1.68469465
139Abnormality of cells of the lymphoid lineage (HP:0012140)1.68339972
140Short thumb (HP:0009778)1.68212271
141Acute myeloid leukemia (HP:0004808)1.67820793
142Long eyelashes (HP:0000527)1.67564041
143Thick nail (HP:0001805)1.67236864
144Abnormality of the Achilles tendon (HP:0005109)1.67114640
145Entropion (HP:0000621)1.66632705
146Overlapping toe (HP:0001845)1.66565831
147Missing ribs (HP:0000921)1.66305012
148Aplasia/Hypoplasia of the thymus (HP:0010515)1.65752984
149Nephroblastoma (Wilms tumor) (HP:0002667)1.65111002
150Optic nerve coloboma (HP:0000588)1.64586051
151Volvulus (HP:0002580)1.63315833
152IgG deficiency (HP:0004315)1.62788940
153Hypertensive crisis (HP:0100735)1.62211692
154Abnormality of the umbilical cord (HP:0010881)1.62206196
155Panhypogammaglobulinemia (HP:0003139)1.61915393
156Ankle contracture (HP:0006466)1.60258815
157Urethral obstruction (HP:0000796)1.58001822
158Natal tooth (HP:0000695)1.57633951
159Abnormality of T cell physiology (HP:0011840)1.55309112
160Aplasia cutis congenita (HP:0001057)1.55148668
161Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.54988791
162Abnormality of the thoracic spine (HP:0100711)1.54418983
163Abnormal foot bone ossification (HP:0010675)1.53957902

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.35806196
2WEE13.65646236
3CDC73.39681005
4EIF2AK13.33378561
5SMG13.11856781
6IRAK32.78306886
7MAP3K92.72869335
8NME22.53070265
9NEK22.45815338
10PLK42.34062164
11PRPF4B2.29452481
12TAF12.29208543
13RPS6KA42.29122527
14ERN12.13111085
15BRSK22.06132667
16CDK122.03767880
17TTK2.02415664
18TSSK61.95240631
19NEK11.91831399
20ACVR1B1.90188058
21PLK11.89110088
22SRPK11.88219205
23MAP3K131.85744224
24TESK21.80241733
25STK101.76516336
26EIF2AK31.63684224
27* AURKB1.60856138
28CDK71.60440208
29VRK21.60219501
30PLK31.53166132
31MKNK11.45800822
32ATR1.40978505
33VRK11.37281455
34TLK11.33867747
35MAP3K81.29712409
36CDK41.29178202
37CHEK21.26522862
38DYRK31.23729115
39MAP4K11.22607884
40STK161.21125547
41STK41.20058051
42NME11.19301914
43EEF2K1.18550469
44PIM21.17410140
45ARAF1.16771480
46BRSK11.16663107
47MST41.16434940
48EPHA21.16363639
49AURKA1.16111886
50PIM11.13586380
51RPS6KB21.09976326
52RIPK41.08927484
53PASK1.08904869
54STK241.08470193
55KDR1.08193466
56RIPK11.06669130
57PBK1.04086508
58CHEK11.03925540
59DMPK1.01405446
60MKNK21.00993491
61TGFBR10.98465597
62CDK80.93780587
63ERBB40.93384908
64ZAK0.92987495
65MAP3K100.91540923
66MOS0.89384884
67TAOK20.87275214
68EIF2AK20.87114306
69SCYL20.86995804
70CAMK1G0.83682686
71ICK0.82994130
72PAK40.82553258
73STK30.81710326
74TESK10.80584713
75MELK0.77584637
76PAK20.77420920
77MAP2K30.76906613
78PNCK0.76290110
79CDK20.75741173
80CAMK1D0.75598826
81CCNB10.75373911
82CDK90.75262811
83ATM0.75131618
84TXK0.72196909
85TRIB30.71907216
86NEK90.71815320
87CDK60.71519181
88CSNK2A20.69592777
89PDGFRA0.69439732
90MAP3K110.68431428
91ZAP700.67383911
92JAK30.66118895
93CSNK2A10.65848800
94LRRK20.65775172
95SIK10.65234562
96TAOK10.64910608
97STK38L0.64652943
98MAP3K30.63969855
99GRK60.61790239
100TYK20.61679322
101IKBKB0.61505576
102LATS20.61330632
103CHUK0.60207008
104RPS6KA50.59019186
105PAK10.58675178
106MARK30.57368300
107CSF1R0.57269448
108ALK0.55012511
109CSNK1E0.54802746
110IRAK40.51592564
111CDK10.50989881
112CLK10.49837082
113BLK0.48606417
114FGFR40.46634082
115PRKCI0.45705851
116PDK20.45572943
117FLT30.43544984
118BTK0.43186234
119LATS10.38820014
120TEC0.38726573
121YES10.38095155
122MAP3K140.34867218
123AKT20.34733024
124MAP3K10.34181550
125BRD40.33463455
126MTOR0.33435789
127NLK0.33417811
128AKT30.32715331
129TBK10.32632666
130BRAF0.32239261
131ADRBK20.31850656
132LYN0.30170111
133MAPKAPK20.29907430
134IKBKE0.29428530

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.22020912
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.83417155
3Mismatch repair_Homo sapiens_hsa034303.63910162
4Ribosome_Homo sapiens_hsa030103.52803135
5Proteasome_Homo sapiens_hsa030503.42350423
6RNA polymerase_Homo sapiens_hsa030203.31320314
7Spliceosome_Homo sapiens_hsa030403.22086073
8RNA transport_Homo sapiens_hsa030133.07319543
9Base excision repair_Homo sapiens_hsa034102.88450575
10Nucleotide excision repair_Homo sapiens_hsa034202.62111254
11Cell cycle_Homo sapiens_hsa041102.61856195
12Homologous recombination_Homo sapiens_hsa034402.54887353
13One carbon pool by folate_Homo sapiens_hsa006702.33926006
14Pyrimidine metabolism_Homo sapiens_hsa002402.31131725
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.12998393
16Basal transcription factors_Homo sapiens_hsa030221.92563855
17Non-homologous end-joining_Homo sapiens_hsa034501.84274898
18Fanconi anemia pathway_Homo sapiens_hsa034601.82195038
19RNA degradation_Homo sapiens_hsa030181.74329105
20mRNA surveillance pathway_Homo sapiens_hsa030151.67755683
21p53 signaling pathway_Homo sapiens_hsa041151.66162196
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.55038583
23Epstein-Barr virus infection_Homo sapiens_hsa051691.42309045
24Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.37643505
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.26960678
26Antigen processing and presentation_Homo sapiens_hsa046121.26524548
27B cell receptor signaling pathway_Homo sapiens_hsa046621.23159173
28Herpes simplex infection_Homo sapiens_hsa051681.21200517
29Folate biosynthesis_Homo sapiens_hsa007901.15888280
30Purine metabolism_Homo sapiens_hsa002301.11890516
31Pentose phosphate pathway_Homo sapiens_hsa000300.95702849
32Primary immunodeficiency_Homo sapiens_hsa053400.94230747
33Sulfur relay system_Homo sapiens_hsa041220.92665343
34Viral carcinogenesis_Homo sapiens_hsa052030.92556569
35Legionellosis_Homo sapiens_hsa051340.92351351
36Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90452150
37Toll-like receptor signaling pathway_Homo sapiens_hsa046200.89174116
38Renal cell carcinoma_Homo sapiens_hsa052110.88932659
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87674195
40Vitamin B6 metabolism_Homo sapiens_hsa007500.87182278
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85973670
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85916666
43HTLV-I infection_Homo sapiens_hsa051660.83763759
44Systemic lupus erythematosus_Homo sapiens_hsa053220.83752259
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.82798483
46NF-kappa B signaling pathway_Homo sapiens_hsa040640.82601508
47Measles_Homo sapiens_hsa051620.81987404
48Drug metabolism - other enzymes_Homo sapiens_hsa009830.77703133
49Pancreatic cancer_Homo sapiens_hsa052120.77190882
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76480075
51TNF signaling pathway_Homo sapiens_hsa046680.75507145
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.72768717
53Protein export_Homo sapiens_hsa030600.72485111
54Oocyte meiosis_Homo sapiens_hsa041140.71765085
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.71675509
56Thyroid cancer_Homo sapiens_hsa052160.71475743
57Shigellosis_Homo sapiens_hsa051310.70588157
58Apoptosis_Homo sapiens_hsa042100.68651972
59Proteoglycans in cancer_Homo sapiens_hsa052050.67794301
60Biosynthesis of amino acids_Homo sapiens_hsa012300.66709266
61Selenocompound metabolism_Homo sapiens_hsa004500.66510097
62MicroRNAs in cancer_Homo sapiens_hsa052060.63271241
63Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62182420
64Hepatitis C_Homo sapiens_hsa051600.61187786
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60250296
66Small cell lung cancer_Homo sapiens_hsa052220.58647355
67Intestinal immune network for IgA production_Homo sapiens_hsa046720.58551601
68RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.58526955
69Leishmaniasis_Homo sapiens_hsa051400.57333760
70N-Glycan biosynthesis_Homo sapiens_hsa005100.54733174
71Prion diseases_Homo sapiens_hsa050200.53728364
72Influenza A_Homo sapiens_hsa051640.52693741
73Non-small cell lung cancer_Homo sapiens_hsa052230.51188153
74Osteoclast differentiation_Homo sapiens_hsa043800.51113008
75Other glycan degradation_Homo sapiens_hsa005110.50784177
76Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50695550
77Hepatitis B_Homo sapiens_hsa051610.50151717
78Notch signaling pathway_Homo sapiens_hsa043300.49804363
79Tuberculosis_Homo sapiens_hsa051520.48547073
80Salmonella infection_Homo sapiens_hsa051320.45787130
81TGF-beta signaling pathway_Homo sapiens_hsa043500.44474515
82Graft-versus-host disease_Homo sapiens_hsa053320.43549734
83Type I diabetes mellitus_Homo sapiens_hsa049400.43415043
84Hematopoietic cell lineage_Homo sapiens_hsa046400.43146644
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.42507713
86Malaria_Homo sapiens_hsa051440.42031023
87Huntingtons disease_Homo sapiens_hsa050160.41826734
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.41420348
89Asthma_Homo sapiens_hsa053100.41297540
90Endometrial cancer_Homo sapiens_hsa052130.40521671
91Allograft rejection_Homo sapiens_hsa053300.40351452
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40317874
93Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39919577
94Autoimmune thyroid disease_Homo sapiens_hsa053200.39919481
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39102761
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38457005
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.36648965
98Adherens junction_Homo sapiens_hsa045200.35732849
99Carbon metabolism_Homo sapiens_hsa012000.35477268
100Viral myocarditis_Homo sapiens_hsa054160.35296600
101Galactose metabolism_Homo sapiens_hsa000520.35063931
102Fructose and mannose metabolism_Homo sapiens_hsa000510.34194549
103Hippo signaling pathway_Homo sapiens_hsa043900.34027698
104Glutathione metabolism_Homo sapiens_hsa004800.32329961
105Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31583841
106Bladder cancer_Homo sapiens_hsa052190.30619148
107Jak-STAT signaling pathway_Homo sapiens_hsa046300.30594487
108Acute myeloid leukemia_Homo sapiens_hsa052210.28975208
109HIF-1 signaling pathway_Homo sapiens_hsa040660.28787197
110Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28644214
111Chronic myeloid leukemia_Homo sapiens_hsa052200.28380518
112Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28238811
113Basal cell carcinoma_Homo sapiens_hsa052170.26079736
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24514594
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.24500389
116Prostate cancer_Homo sapiens_hsa052150.23442387
117Colorectal cancer_Homo sapiens_hsa052100.23208721
118T cell receptor signaling pathway_Homo sapiens_hsa046600.23127244
119Leukocyte transendothelial migration_Homo sapiens_hsa046700.22854526
120Pathways in cancer_Homo sapiens_hsa052000.20965567
121Regulation of autophagy_Homo sapiens_hsa041400.19204327
122Toxoplasmosis_Homo sapiens_hsa051450.19200799
123Parkinsons disease_Homo sapiens_hsa050120.19174617
124Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.17572294
125Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.17410506
126mTOR signaling pathway_Homo sapiens_hsa041500.16519978
127Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.15651978

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