UTP23

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.44092518
2DNA double-strand break processing (GO:0000729)4.26622658
3mitotic metaphase plate congression (GO:0007080)4.05687655
4DNA replication checkpoint (GO:0000076)4.04316754
5establishment of protein localization to mitochondrial membrane (GO:0090151)4.03090867
6termination of RNA polymerase III transcription (GO:0006386)3.97372077
7transcription elongation from RNA polymerase III promoter (GO:0006385)3.97372077
8ATP synthesis coupled proton transport (GO:0015986)3.93121681
9energy coupled proton transport, down electrochemical gradient (GO:0015985)3.93121681
10maturation of SSU-rRNA (GO:0030490)3.91868624
11CENP-A containing nucleosome assembly (GO:0034080)3.77412843
12DNA replication initiation (GO:0006270)3.76429649
13DNA deamination (GO:0045006)3.67833957
14proteasome assembly (GO:0043248)3.67238025
15somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.66297057
16isotype switching (GO:0045190)3.66297057
17somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.66297057
18telomere maintenance via semi-conservative replication (GO:0032201)3.64696796
19DNA catabolic process, exonucleolytic (GO:0000738)3.64693074
20respiratory chain complex IV assembly (GO:0008535)3.61934468
21ribosome biogenesis (GO:0042254)3.60921860
22spliceosomal snRNP assembly (GO:0000387)3.59163780
23DNA strand elongation involved in DNA replication (GO:0006271)3.58240074
24rRNA modification (GO:0000154)3.56975367
25telomere maintenance via recombination (GO:0000722)3.55746289
26chromatin remodeling at centromere (GO:0031055)3.54691247
27response to pheromone (GO:0019236)3.51195144
28protein complex biogenesis (GO:0070271)3.50976610
29mitochondrial respiratory chain complex assembly (GO:0033108)3.50723223
30purine nucleobase biosynthetic process (GO:0009113)3.49940495
31DNA strand elongation (GO:0022616)3.48914224
32ribonucleoprotein complex biogenesis (GO:0022613)3.48812127
33maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.48762324
34ribosomal small subunit assembly (GO:0000028)3.45256564
35regulation of mitochondrial translation (GO:0070129)3.45130123
36kinetochore assembly (GO:0051382)3.45061540
37protein K6-linked ubiquitination (GO:0085020)3.44986879
38regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.41377148
39regulation of mitotic spindle checkpoint (GO:1903504)3.41377148
40transcription elongation from RNA polymerase I promoter (GO:0006362)3.40464336
41kinetochore organization (GO:0051383)3.40157422
42ribosomal large subunit biogenesis (GO:0042273)3.39966686
43termination of RNA polymerase I transcription (GO:0006363)3.39220995
44metaphase plate congression (GO:0051310)3.39202612
457-methylguanosine RNA capping (GO:0009452)3.35965000
46RNA capping (GO:0036260)3.35965000
47mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.34103718
48cytochrome complex assembly (GO:0017004)3.32649025
497-methylguanosine mRNA capping (GO:0006370)3.30888986
50nucleobase biosynthetic process (GO:0046112)3.30550999
51regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.29026443
52* rRNA processing (GO:0006364)3.28776667
53chaperone-mediated protein transport (GO:0072321)3.27012850
54meiotic chromosome segregation (GO:0045132)3.26296829
55pseudouridine synthesis (GO:0001522)3.25654469
56regulation of double-strand break repair via homologous recombination (GO:0010569)3.23268997
57mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.23077772
58mitochondrial respiratory chain complex I assembly (GO:0032981)3.23077772
59NADH dehydrogenase complex assembly (GO:0010257)3.23077772
60mitotic recombination (GO:0006312)3.22294875
61maturation of 5.8S rRNA (GO:0000460)3.21404654
62electron transport chain (GO:0022900)3.20845585
63viral mRNA export from host cell nucleus (GO:0046784)3.20551562
64respiratory electron transport chain (GO:0022904)3.20349990
65transcription from RNA polymerase I promoter (GO:0006360)3.20322735
66water-soluble vitamin biosynthetic process (GO:0042364)3.20092772
67establishment of integrated proviral latency (GO:0075713)3.19517160
68* rRNA metabolic process (GO:0016072)3.19341356
69DNA replication-independent nucleosome assembly (GO:0006336)3.16559040
70DNA replication-independent nucleosome organization (GO:0034724)3.16559040
71ribosomal small subunit biogenesis (GO:0042274)3.16191837
72regulation of nuclear cell cycle DNA replication (GO:0033262)3.14848758
73ribosome assembly (GO:0042255)3.14171656
74SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.14055240
75cotranslational protein targeting to membrane (GO:0006613)3.13871451
76transcription-coupled nucleotide-excision repair (GO:0006283)3.12088794
77telomere maintenance via telomere lengthening (GO:0010833)3.12036790
78translational termination (GO:0006415)3.11533592
79peptidyl-histidine modification (GO:0018202)3.11157515
80RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.11092827
81translation (GO:0006412)3.09473159
82spliceosomal complex assembly (GO:0000245)3.07218937
83replication fork processing (GO:0031297)3.06152164
84protein targeting to ER (GO:0045047)3.05508838
85double-strand break repair via homologous recombination (GO:0000724)3.05493918
86platelet dense granule organization (GO:0060155)3.03756091
87recombinational repair (GO:0000725)3.02936491
88centriole replication (GO:0007099)3.02437247
89establishment of chromosome localization (GO:0051303)2.98675210
90regulation of centriole replication (GO:0046599)2.98152672
91somatic recombination of immunoglobulin gene segments (GO:0016447)2.97481303
92establishment of protein localization to endoplasmic reticulum (GO:0072599)2.95286102
93histone exchange (GO:0043486)2.95200720
94viral transcription (GO:0019083)2.94605321
95protein localization to kinetochore (GO:0034501)2.93230459
96translational initiation (GO:0006413)2.91142854
97negative regulation of DNA-dependent DNA replication (GO:2000104)2.89720351
98signal peptide processing (GO:0006465)2.89221394
99protein localization to chromosome, centromeric region (GO:0071459)2.86997277
100rRNA methylation (GO:0031167)2.86591251
101telomere maintenance via telomerase (GO:0007004)2.86332327
102protein localization to endoplasmic reticulum (GO:0070972)2.85879219
103transcription initiation from RNA polymerase I promoter (GO:0006361)2.85499618
104tRNA processing (GO:0008033)2.85426544
105somatic diversification of immunoglobulins (GO:0016445)2.84640477
106DNA-templated transcription, elongation (GO:0006354)2.82775117
107double-strand break repair via nonhomologous end joining (GO:0006303)2.82462368
108non-recombinational repair (GO:0000726)2.82462368
109mismatch repair (GO:0006298)2.82055284
110microtubule depolymerization (GO:0007019)2.81580875
111transcription elongation from RNA polymerase II promoter (GO:0006368)2.81059783
112DNA-templated transcription, termination (GO:0006353)2.80842171
113RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.80206637
114tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.80206637
115mitochondrial RNA metabolic process (GO:0000959)2.79555267
116nucleotide-excision repair, DNA gap filling (GO:0006297)2.78982949
117inner mitochondrial membrane organization (GO:0007007)2.78657755
118synapsis (GO:0007129)2.78585872
119negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.78557001
120cellular component biogenesis (GO:0044085)2.78250978
121resolution of meiotic recombination intermediates (GO:0000712)2.77495071
122anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.77325060
123regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.76786549
124tRNA methylation (GO:0030488)2.75947625
125intra-S DNA damage checkpoint (GO:0031573)2.75525635
126attachment of spindle microtubules to kinetochore (GO:0008608)2.75524723
127organelle disassembly (GO:1903008)2.73512607
128positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.72499195
129exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.72233843
130DNA synthesis involved in DNA repair (GO:0000731)2.71968590
131signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.70986266
132signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.70986266
133signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.70986266
134nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.69917389
135DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.68924371
136telomere organization (GO:0032200)2.68504210
137* ncRNA processing (GO:0034470)2.67615823
138intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.66804058
139signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.66804058
140histone mRNA metabolic process (GO:0008334)2.66429038
141telomere maintenance (GO:0000723)2.66307687
142L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.65698576
143G1/S transition of mitotic cell cycle (GO:0000082)2.63379798
144cell cycle G1/S phase transition (GO:0044843)2.63379798
145signal transduction involved in cell cycle checkpoint (GO:0072395)2.63019720
146signal transduction involved in DNA damage checkpoint (GO:0072422)2.62559120
147signal transduction involved in DNA integrity checkpoint (GO:0072401)2.62559120
148regulation of spindle organization (GO:0090224)2.61451731
149DNA damage response, detection of DNA damage (GO:0042769)2.60352039
150positive regulation of viral transcription (GO:0050434)2.59779260
151DNA-dependent DNA replication (GO:0006261)2.58409569
152* ncRNA metabolic process (GO:0034660)2.57752782
153DNA ligation (GO:0006266)2.57697536
154deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.57131344
155spindle checkpoint (GO:0031577)2.56388123
156nucleotide-excision repair (GO:0006289)2.53424363

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.79292881
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.17062912
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.77956890
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.51449301
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.46853853
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.45024997
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.38705532
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.38615232
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.00981248
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.98777547
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.95789332
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.77497386
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.74227043
14ZNF274_21170338_ChIP-Seq_K562_Hela2.72635704
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.63431233
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.61568537
17* VDR_23849224_ChIP-Seq_CD4+_Human2.55480733
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.54329645
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.51619263
20MYC_19079543_ChIP-ChIP_MESCs_Mouse2.51519296
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.48239297
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.47183990
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.47010220
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.42028022
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33318724
26TP63_19390658_ChIP-ChIP_HaCaT_Human2.29066704
27EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.26596220
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21472214
29NOTCH1_21737748_ChIP-Seq_TLL_Human2.21118803
30FOXP3_21729870_ChIP-Seq_TREG_Human2.18466540
31VDR_22108803_ChIP-Seq_LS180_Human2.13432206
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.13222229
33ELK1_19687146_ChIP-ChIP_HELA_Human2.11448068
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.00522180
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.99248501
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.96397432
37FUS_26573619_Chip-Seq_HEK293_Human1.94676771
38DCP1A_22483619_ChIP-Seq_HELA_Human1.93060339
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91792689
40* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89665369
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.89248320
42XRN2_22483619_ChIP-Seq_HELA_Human1.88122069
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.85510735
44E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79618770
45HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.79408172
46YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.74574393
47TTF2_22483619_ChIP-Seq_HELA_Human1.70399463
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.67182208
49IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.67158014
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66765848
51MYCN_18555785_ChIP-Seq_MESCs_Mouse1.66002220
52TAF15_26573619_Chip-Seq_HEK293_Human1.65135382
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.64831674
54* GABP_19822575_ChIP-Seq_HepG2_Human1.63259743
55KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.58873246
56SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.58182637
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52595115
58NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52517998
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.52379991
60POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46318799
61IRF8_21731497_ChIP-ChIP_J774_Mouse1.45619060
62ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.38552587
63PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.37327046
64IGF1R_20145208_ChIP-Seq_DFB_Human1.36003077
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.34543269
66* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31288758
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.28741885
68ZFP57_27257070_Chip-Seq_ESCs_Mouse1.26643513
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.25523937
70AR_21909140_ChIP-Seq_LNCAP_Human1.25070589
71* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.24089382
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23386433
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.22834315
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22602270
75ER_23166858_ChIP-Seq_MCF-7_Human1.22540344
76MYC_18940864_ChIP-ChIP_HL60_Human1.17930914
77IRF1_19129219_ChIP-ChIP_H3396_Human1.16555906
78P300_19829295_ChIP-Seq_ESCs_Human1.16258215
79* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15083550
80POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14321236
81* SPI1_23547873_ChIP-Seq_NB4_Human1.14284227
82KDM5A_27292631_Chip-Seq_BREAST_Human1.11792820
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10323611
84CIITA_25753668_ChIP-Seq_RAJI_Human1.07111416
85* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06968176
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06066839
87IRF8_22096565_ChIP-ChIP_GC-B_Human1.03232112
88RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.02559713
89KAP1_22055183_ChIP-Seq_ESCs_Mouse1.01997829
90* CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.99428271
91HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.96468263
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94626238
93* ELF5_23300383_ChIP-Seq_T47D_Human0.94265020
94E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.94020629
95TP53_22573176_ChIP-Seq_HFKS_Human0.93495345
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92590841
97CTBP2_25329375_ChIP-Seq_LNCAP_Human0.90583665
98RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89096921
99KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.88201536
100STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87140264
101ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.86497070
102BP1_19119308_ChIP-ChIP_Hs578T_Human0.86390649
103SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85546277
104FOXA1_25329375_ChIP-Seq_VCAP_Human0.84210516
105FOXA1_27270436_Chip-Seq_PROSTATE_Human0.84210516
106SOX2_19829295_ChIP-Seq_ESCs_Human0.83201339
107NANOG_19829295_ChIP-Seq_ESCs_Human0.83201339
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.82845656
109ZFX_18555785_ChIP-Seq_MESCs_Mouse0.82252374
110NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.82179710
111TFEB_21752829_ChIP-Seq_HELA_Human0.81749754
112TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81203343
113NFE2_27457419_Chip-Seq_LIVER_Mouse0.80683626
114CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.79929510
115CTBP1_25329375_ChIP-Seq_LNCAP_Human0.79528473
116CBP_20019798_ChIP-Seq_JUKART_Human0.79422290
117IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.79422290
118SOX2_16153702_ChIP-ChIP_HESCs_Human0.79354875
119CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.78721512
120SUZ12_27294783_Chip-Seq_NPCs_Mouse0.77004802
121GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.76488254
122* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75540787
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.73483655
124CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.70678615
125BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.69961160
126* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.68873550
127MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.68419907
128SALL1_21062744_ChIP-ChIP_HESCs_Human0.63091828
129EGR1_19374776_ChIP-ChIP_THP-1_Human0.62663571
130SOX17_20123909_ChIP-Seq_XEN_Mouse0.61338281
131EZH2_27294783_Chip-Seq_NPCs_Mouse0.59334296
132EWS_26573619_Chip-Seq_HEK293_Human0.59047840

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.71500068
2MP0010094_abnormal_chromosome_stability3.69132726
3MP0008058_abnormal_DNA_repair3.68099332
4MP0003111_abnormal_nucleus_morphology3.55557056
5MP0008057_abnormal_DNA_replication3.50019990
6MP0006292_abnormal_olfactory_placode3.37097582
7MP0003077_abnormal_cell_cycle3.08715579
8MP0004957_abnormal_blastocyst_morpholog2.89107737
9MP0008007_abnormal_cellular_replicative2.52713975
10MP0003786_premature_aging2.35015815
11MP0003136_yellow_coat_color2.26697018
12MP0008932_abnormal_embryonic_tissue2.21643206
13MP0008877_abnormal_DNA_methylation2.11972983
14MP0000569_abnormal_digit_pigmentation2.09902889
15MP0000427_abnormal_hair_cycle2.09786033
16MP0006072_abnormal_retinal_apoptosis2.07547570
17MP0002396_abnormal_hematopoietic_system2.05753464
18MP0000566_synostosis2.04545462
19MP0001986_abnormal_taste_sensitivity2.01094122
20MP0003718_maternal_effect1.87620194
21MP0006035_abnormal_mitochondrial_morpho1.86084107
22MP0002102_abnormal_ear_morphology1.81159406
23MP0005645_abnormal_hypothalamus_physiol1.77982518
24MP0003806_abnormal_nucleotide_metabolis1.75901623
25MP0009333_abnormal_splenocyte_physiolog1.70900702
26MP0000490_abnormal_crypts_of1.70097645
27MP0000015_abnormal_ear_pigmentation1.70095616
28MP0006036_abnormal_mitochondrial_physio1.67932522
29MP0005671_abnormal_response_to1.64869541
30MP0002277_abnormal_respiratory_mucosa1.63043455
31MP0001835_abnormal_antigen_presentation1.59183605
32MP0003763_abnormal_thymus_physiology1.55925270
33MP0002132_abnormal_respiratory_system1.54809138
34MP0005075_abnormal_melanosome_morpholog1.52322281
35MP0004142_abnormal_muscle_tone1.50694015
36MP0003011_delayed_dark_adaptation1.47325734
37MP0002148_abnormal_hypersensitivity_rea1.41172822
38MP0003195_calcinosis1.40827774
39MP0004381_abnormal_hair_follicle1.36290221
40MP0001800_abnormal_humoral_immune1.35574052
41MP0002938_white_spotting1.35091360
42MP0009785_altered_susceptibility_to1.34775765
43MP0003315_abnormal_perineum_morphology1.32015646
44MP0001188_hyperpigmentation1.31849726
45MP0002160_abnormal_reproductive_system1.31341972
46MP0005253_abnormal_eye_physiology1.30699464
47MP0000350_abnormal_cell_proliferation1.30057505
48MP0002751_abnormal_autonomic_nervous1.28487357
49MP0002398_abnormal_bone_marrow1.26829147
50MP0005000_abnormal_immune_tolerance1.25200338
51MP0008260_abnormal_autophagy1.25088396
52MP0002452_abnormal_antigen_presenting1.24304636
53MP0002723_abnormal_immune_serum1.23008006
54MP0005084_abnormal_gallbladder_morpholo1.22816432
55MP0004043_abnormal_pH_regulation1.21828170
56MP0005174_abnormal_tail_pigmentation1.20216685
57MP0005551_abnormal_eye_electrophysiolog1.19864153
58MP0002420_abnormal_adaptive_immunity1.19781045
59MP0001819_abnormal_immune_cell1.18969686
60MP0002837_dystrophic_cardiac_calcinosis1.18147674
61MP0000858_altered_metastatic_potential1.17058502
62MP0003787_abnormal_imprinting1.16304772
63MP0001919_abnormal_reproductive_system1.15851592
64MP0001853_heart_inflammation1.13024893
65MP0002163_abnormal_gland_morphology1.12160368
66MP0003123_paternal_imprinting1.12129128
67MP0000313_abnormal_cell_death1.11548116
68MP0000689_abnormal_spleen_morphology1.11394002
69MP0005025_abnormal_response_to1.11293836
70MP0002095_abnormal_skin_pigmentation1.10026322
71MP0003937_abnormal_limbs/digits/tail_de1.09114936
72MP0002210_abnormal_sex_determination1.08916762
73MP0000703_abnormal_thymus_morphology1.08750713
74MP0000716_abnormal_immune_system1.08717258
75MP0002722_abnormal_immune_system1.08171050
76MP0001293_anophthalmia1.07541844
77MP0001764_abnormal_homeostasis1.06708583
78MP0002234_abnormal_pharynx_morphology1.06256332
79MP0000372_irregular_coat_pigmentation1.06171222
80MP0000653_abnormal_sex_gland1.06138720
81MP0000358_abnormal_cell_content/1.02946666
82MP0002419_abnormal_innate_immunity1.00967265
83MP0000631_abnormal_neuroendocrine_gland0.99850746
84MP0009046_muscle_twitch0.99304218
85MP0002429_abnormal_blood_cell0.99152921
86MP0004133_heterotaxia0.98692063
87MP0003866_abnormal_defecation0.98586401
88MP0000647_abnormal_sebaceous_gland0.98274772
89MP0005387_immune_system_phenotype0.98006889
90MP0001790_abnormal_immune_system0.98006889
91MP0004808_abnormal_hematopoietic_stem0.97624656
92MP0001119_abnormal_female_reproductive0.96990337
93MP0002019_abnormal_tumor_incidence0.96768926
94MP0003938_abnormal_ear_development0.96337173
95MP0010678_abnormal_skin_adnexa0.96222950
96MP0009697_abnormal_copulation0.95741360
97MP0001542_abnormal_bone_strength0.94993425
98MP0001730_embryonic_growth_arrest0.94831657
99MP0001697_abnormal_embryo_size0.94465604
100MP0002736_abnormal_nociception_after0.94067615
101MP0008872_abnormal_physiological_respon0.93288065
102MP0003121_genomic_imprinting0.92260163
103MP0001529_abnormal_vocalization0.91574384
104MP0002928_abnormal_bile_duct0.91522836
105MP0010030_abnormal_orbit_morphology0.90753008
106MP0008995_early_reproductive_senescence0.89707839
107MP0005171_absent_coat_pigmentation0.89396675
108MP0003724_increased_susceptibility_to0.88531204
109MP0004147_increased_porphyrin_level0.87777152
110MP0002405_respiratory_system_inflammati0.87658283
111MP0001672_abnormal_embryogenesis/_devel0.87545284
112MP0005380_embryogenesis_phenotype0.87545284
113MP0005266_abnormal_metabolism0.85972515
114MP0003252_abnormal_bile_duct0.85828304
115MP0003950_abnormal_plasma_membrane0.85489956
116MP0001186_pigmentation_phenotype0.85392237
117MP0002638_abnormal_pupillary_reflex0.84226942
118MP0005409_darkened_coat_color0.83087142
119MP0001968_abnormal_touch/_nociception0.82949704
120MP0001286_abnormal_eye_development0.82355893
121MP0005220_abnormal_exocrine_pancreas0.82089437
122MP0003448_altered_tumor_morphology0.81978004
123MP0010155_abnormal_intestine_physiology0.80218477
124MP0003436_decreased_susceptibility_to0.79626569
125MP0001929_abnormal_gametogenesis0.78871157
126MP0002735_abnormal_chemical_nociception0.78488857
127MP0001145_abnormal_male_reproductive0.78428670
128MP0008875_abnormal_xenobiotic_pharmacok0.77620806
129MP0002006_tumorigenesis0.76468695
130MP0000685_abnormal_immune_system0.76190399
131MP0003186_abnormal_redox_activity0.75033140
132MP0003698_abnormal_male_reproductive0.74303871
133MP0002822_catalepsy0.73398799
134MP0003890_abnormal_embryonic-extraembry0.72840804
135MP0004215_abnormal_myocardial_fiber0.72840490
136MP0003941_abnormal_skin_development0.72672012
137MP0005646_abnormal_pituitary_gland0.72503745
138MP0005389_reproductive_system_phenotype0.71593334
139MP0004134_abnormal_chest_morphology0.71590176
140MP0005379_endocrine/exocrine_gland_phen0.71040720
141MP0005451_abnormal_body_composition0.70947333
142MP0006082_CNS_inflammation0.70772175
143MP0000383_abnormal_hair_follicle0.69750033
144MP0002254_reproductive_system_inflammat0.67079054
145MP0002009_preneoplasia0.67028285
146MP0000516_abnormal_urinary_system0.66715987
147MP0005367_renal/urinary_system_phenotyp0.66715987
148MP0001881_abnormal_mammary_gland0.66585253
149MP0005391_vision/eye_phenotype0.64226490
150MP0000371_diluted_coat_color0.64209793
151MP0005187_abnormal_penis_morphology0.64000947
152MP0001944_abnormal_pancreas_morphology0.63470851

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.87930433
2Chromsome breakage (HP:0040012)4.59721285
3Birth length less than 3rd percentile (HP:0003561)3.98760273
4Acute necrotizing encephalopathy (HP:0006965)3.67768290
53-Methylglutaconic aciduria (HP:0003535)3.44790580
6Molar tooth sign on MRI (HP:0002419)3.44577920
7Abnormality of midbrain morphology (HP:0002418)3.44577920
8Mitochondrial inheritance (HP:0001427)3.40731284
9Increased CSF lactate (HP:0002490)3.33994757
10Abnormality of the preputium (HP:0100587)3.28321136
11Reticulocytopenia (HP:0001896)3.27468970
12Acute encephalopathy (HP:0006846)3.24918701
13Progressive macrocephaly (HP:0004481)3.24303762
14Abnormal mitochondria in muscle tissue (HP:0008316)3.20812643
15Meckel diverticulum (HP:0002245)3.19401567
16Aplasia/Hypoplasia of the uvula (HP:0010293)3.11487409
17Rough bone trabeculation (HP:0100670)3.09494425
18Volvulus (HP:0002580)3.08093586
19Abnormality of the ileum (HP:0001549)3.07414056
20Patellar aplasia (HP:0006443)3.06191959
21Abnormality of chromosome stability (HP:0003220)3.05251892
22Breast hypoplasia (HP:0003187)3.00194365
23Duplicated collecting system (HP:0000081)2.97415296
24Increased hepatocellular lipid droplets (HP:0006565)2.96787696
25Abnormality of the pons (HP:0007361)2.96325393
26Hepatocellular necrosis (HP:0001404)2.92323448
27Lipid accumulation in hepatocytes (HP:0006561)2.86263223
28Hypoplasia of the pons (HP:0012110)2.83358906
29Aplasia/Hypoplasia of the patella (HP:0006498)2.82401940
30Hepatic necrosis (HP:0002605)2.77952483
31Renal cortical cysts (HP:0000803)2.69813841
32Bone marrow hypocellularity (HP:0005528)2.66379641
33Congenital, generalized hypertrichosis (HP:0004540)2.65328886
34Absent radius (HP:0003974)2.64140665
35Premature graying of hair (HP:0002216)2.54956930
36Methylmalonic acidemia (HP:0002912)2.54425855
37Ectopic kidney (HP:0000086)2.53823449
38Abnormality of DNA repair (HP:0003254)2.53432382
39Increased serum lactate (HP:0002151)2.53019270
40Absent forearm bone (HP:0003953)2.52287562
41Aplasia involving forearm bones (HP:0009822)2.52287562
42Abnormality of the renal collecting system (HP:0004742)2.49379381
43Abnormality of the renal cortex (HP:0011035)2.47790418
44Triphalangeal thumb (HP:0001199)2.47755157
45Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.45862290
46Abnormality of alanine metabolism (HP:0010916)2.45862290
47Hyperalaninemia (HP:0003348)2.45862290
48Cleft eyelid (HP:0000625)2.44796349
49Type II lissencephaly (HP:0007260)2.43329863
50Aplastic anemia (HP:0001915)2.41429385
51Abnormal trabecular bone morphology (HP:0100671)2.41200497
52Clubbing of toes (HP:0100760)2.40823805
53Severe combined immunodeficiency (HP:0004430)2.40577301
54Concave nail (HP:0001598)2.38205796
55Cerebral edema (HP:0002181)2.36126691
56Congenital stationary night blindness (HP:0007642)2.35975883
57Small intestinal stenosis (HP:0012848)2.35669217
58Duodenal stenosis (HP:0100867)2.35669217
59Horseshoe kidney (HP:0000085)2.35666152
60Cerebral hypomyelination (HP:0006808)2.35178435
61Large for gestational age (HP:0001520)2.34202221
62Type 2 muscle fiber atrophy (HP:0003554)2.33802844
63Nephronophthisis (HP:0000090)2.33132220
64Carpal bone hypoplasia (HP:0001498)2.31932599
65Adrenal hypoplasia (HP:0000835)2.31799948
66Myelodysplasia (HP:0002863)2.31210047
67Absent thumb (HP:0009777)2.27309526
68Cellular immunodeficiency (HP:0005374)2.22713703
69Type I transferrin isoform profile (HP:0003642)2.21540522
70Lactic acidosis (HP:0003128)2.17186498
71Prostate neoplasm (HP:0100787)2.15424018
72Pancreatic cysts (HP:0001737)2.14796336
73Oligodactyly (hands) (HP:0001180)2.14732835
74Lymphoma (HP:0002665)2.12270482
75Pallor (HP:0000980)2.11269063
76Short thumb (HP:0009778)2.10935429
77Aplasia/Hypoplasia of the tibia (HP:0005772)2.10807657
78Muscle fiber atrophy (HP:0100295)2.09610894
79Hypoplasia of the capital femoral epiphysis (HP:0003090)2.08472710
80Optic disc pallor (HP:0000543)2.07092713
81Abnormality of the duodenum (HP:0002246)2.06587215
82Agnosia (HP:0010524)2.05830130
83Combined immunodeficiency (HP:0005387)2.05145938
84Obstructive lung disease (HP:0006536)2.04643752
85Chronic obstructive pulmonary disease (HP:0006510)2.04643752
86Cerebellar dysplasia (HP:0007033)2.04341940
87Impulsivity (HP:0100710)2.03694187
88Abnormality of methionine metabolism (HP:0010901)2.03657893
89Intestinal atresia (HP:0011100)2.02960175
90Tracheoesophageal fistula (HP:0002575)2.02036527
91Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.00161897
92Aplasia/Hypoplasia of the earlobes (HP:0009906)2.00142294
93Pendular nystagmus (HP:0012043)1.99716950
94Colon cancer (HP:0003003)1.99099849
95Oral leukoplakia (HP:0002745)1.98482086
96Sloping forehead (HP:0000340)1.98438082
97Pancytopenia (HP:0001876)1.98371174
98Abnormality of the renal medulla (HP:0100957)1.98020971
99Short tibia (HP:0005736)1.97104840
100Aplasia/Hypoplasia of the sacrum (HP:0008517)1.95767486
101Parakeratosis (HP:0001036)1.95412111
102Abnormality of eosinophils (HP:0001879)1.95309712
103Neuroendocrine neoplasm (HP:0100634)1.95091278
104Chronic hepatic failure (HP:0100626)1.94227420
105Abnormality of cells of the erythroid lineage (HP:0012130)1.94034895
106Entropion (HP:0000621)1.93148009
107Renal Fanconi syndrome (HP:0001994)1.92910912
108Microvesicular hepatic steatosis (HP:0001414)1.92731808
109Degeneration of anterior horn cells (HP:0002398)1.92697393
110Abnormality of the anterior horn cell (HP:0006802)1.92697393
111Medial flaring of the eyebrow (HP:0010747)1.92512285
112Pancreatic fibrosis (HP:0100732)1.92245868
113Abnormal number of erythroid precursors (HP:0012131)1.91874084
114Nephroblastoma (Wilms tumor) (HP:0002667)1.90321405
115Neoplasm of the adrenal gland (HP:0100631)1.89937066
116Abnormality of the labia minora (HP:0012880)1.89421318
117IgM deficiency (HP:0002850)1.89321435
118Sparse eyelashes (HP:0000653)1.88907740
119Respiratory failure (HP:0002878)1.86803837
120Reduced antithrombin III activity (HP:0001976)1.86280550
121Short middle phalanx of the 5th finger (HP:0004220)1.85846098
122Macrocytic anemia (HP:0001972)1.84099829
123Oligodactyly (HP:0012165)1.83958994
124Thyroiditis (HP:0100646)1.83955418
125Abnormality of the columella (HP:0009929)1.83662307
126Supernumerary spleens (HP:0009799)1.82320706
127Ketoacidosis (HP:0001993)1.81880096
128IgG deficiency (HP:0004315)1.79852825
129Abnormal number of incisors (HP:0011064)1.79512758
130Abnormality of the prostate (HP:0008775)1.79328133
131Abnormality of the carotid arteries (HP:0005344)1.79124099
132Sclerocornea (HP:0000647)1.79121186
133Methylmalonic aciduria (HP:0012120)1.79027359
134Hypothermia (HP:0002045)1.78830546
135Aplasia/Hypoplasia involving the musculature (HP:0001460)1.77826432
136Abnormal spermatogenesis (HP:0008669)1.77611327
137True hermaphroditism (HP:0010459)1.77481007
138Embryonal renal neoplasm (HP:0011794)1.77086832
139Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.76817391
140Decreased activity of mitochondrial respiratory chain (HP:0008972)1.76817391
141Constricted visual fields (HP:0001133)1.76677747
142Aplasia/Hypoplasia of the tongue (HP:0010295)1.75921726
143Ureteral duplication (HP:0000073)1.75500935
144Lethargy (HP:0001254)1.75249773
145Furrowed tongue (HP:0000221)1.74546304
146Duplication of thumb phalanx (HP:0009942)1.74281824
147Septo-optic dysplasia (HP:0100842)1.73532198
148Neoplasm of the adrenal cortex (HP:0100641)1.72725848
14911 pairs of ribs (HP:0000878)1.71725229
150Recurrent abscess formation (HP:0002722)1.71456125
151Decreased electroretinogram (ERG) amplitude (HP:0000654)1.71384292
152Leukodystrophy (HP:0002415)1.70928405
153Pheochromocytoma (HP:0002666)1.70492604
154Abnormal protein glycosylation (HP:0012346)1.70151956
155Abnormal glycosylation (HP:0012345)1.70151956
156Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.70151956
157Abnormal protein N-linked glycosylation (HP:0012347)1.70151956
158Retrobulbar optic neuritis (HP:0100654)1.69823841
159Optic neuritis (HP:0100653)1.69823841
160Granulocytopenia (HP:0001913)1.69045447
161Pulmonary fibrosis (HP:0002206)1.67805031
162Median cleft lip (HP:0000161)1.67307763
163Exertional dyspnea (HP:0002875)1.66235887
164Abnormality of serum amino acid levels (HP:0003112)1.65342551
165Gastrointestinal atresia (HP:0002589)1.64897890
166Abnormality of aspartate family amino acid metabolism (HP:0010899)1.64201354

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.76165089
2MKNK23.33955505
3EIF2AK13.18646349
4PLK43.15845472
5SRPK13.12141977
6FRK2.82708617
7STK162.68809792
8WEE12.62896006
9MKNK12.57961259
10VRK22.48516052
11EIF2AK32.36321784
12IRAK32.30831213
13NME22.30020835
14ZAK2.20616775
15TRIM282.14389573
16CDC72.10126899
17VRK12.05520023
18WNK32.04334965
19TXK1.92364420
20IRAK41.86318789
21ACVR1B1.83026050
22BRSK21.82954843
23EIF2AK21.75395597
24PBK1.68801241
25MAP4K21.64083833
26ERBB31.61261238
27TLK11.59174936
28NEK11.54581670
29CDK71.52585836
30PLK11.51393992
31TTK1.46898215
32BRSK11.41707637
33TNIK1.37686677
34PLK31.37327308
35ATR1.31189078
36CHEK21.30538771
37TGFBR11.30313058
38STK391.28601368
39WNK41.28205446
40DYRK31.28139740
41AURKB1.26177405
42MAP3K121.25506507
43RPS6KA41.23470278
44PIM21.22837110
45SIK31.20210953
46NEK61.19913166
47NEK21.19670377
48MAP3K141.17498392
49STK38L1.16913656
50MAP3K41.13883262
51TAF11.13080492
52PNCK1.12836886
53BMPR1B1.12468137
54INSRR1.11123320
55STK41.07038728
56CLK11.04368075
57TSSK61.01628369
58BRD40.98607746
59DYRK20.96504588
60YES10.96059993
61MAP4K10.95953705
62IKBKB0.95262362
63NLK0.95080100
64CDK80.93846476
65CHEK10.89281644
66PIM10.87619996
67JAK30.87351595
68MARK30.87098351
69NUAK10.86950071
70OXSR10.85410169
71CCNB10.83374439
72TEC0.82845610
73AURKA0.82051556
74BLK0.81766510
75BMPR20.80024347
76CAMKK20.76451382
77AKT30.75812591
78CDK120.75039165
79CDK40.72614842
80RPS6KA50.72543444
81PASK0.70689098
82CASK0.69588907
83STK100.69550684
84MAP2K70.69316771
85ATM0.67407780
86CSNK2A10.66681784
87EPHA20.65399626
88MUSK0.62553802
89BTK0.61261509
90IKBKE0.60757521
91CDK30.60408327
92MST40.59321832
93ADRBK20.58207746
94KIT0.57990177
95ADRBK10.57254094
96LYN0.56944956
97IRAK20.53232983
98MELK0.52821360
99IRAK10.51817353
100BRAF0.51299924
101TESK20.50337028
102CDK20.50245515
103CHUK0.50032383
104TYK20.49890477
105CSNK2A20.49770602
106PLK20.49282784
107GRK70.48129318
108NME10.47724039
109CDK90.46812573
110PAK30.46103312
111CDK10.45205264
112NEK90.44434871
113STK30.44224836
114CSNK1G20.44149487
115PIK3CA0.43997208
116PRKCE0.42930612
117MAPK110.40691515
118RPS6KB20.40502188
119PRKCG0.40086752
120MAP3K80.39895993
121LCK0.39722225
122CSNK1E0.39551203
123TAOK30.38538521
124ERBB40.37590502
125CSNK1G10.37261606
126GRK10.37131187
127TAOK20.37057138
128PAK10.34971929
129CSNK1G30.34811354
130BCR0.34795126
131MAPK130.34460070
132STK240.33329038
133PRKCI0.32474586
134PIK3CG0.30493761
135CSNK1A1L0.29008118

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030203.93939010
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.63354034
3DNA replication_Homo sapiens_hsa030303.59274753
4Proteasome_Homo sapiens_hsa030503.10897681
5Mismatch repair_Homo sapiens_hsa034303.06394324
6Homologous recombination_Homo sapiens_hsa034403.06064263
7Ribosome_Homo sapiens_hsa030103.04409697
8Spliceosome_Homo sapiens_hsa030402.78320518
9Fanconi anemia pathway_Homo sapiens_hsa034602.69413209
10Non-homologous end-joining_Homo sapiens_hsa034502.46607794
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.46477274
12Pyrimidine metabolism_Homo sapiens_hsa002402.44502166
13Base excision repair_Homo sapiens_hsa034102.43399158
14Nucleotide excision repair_Homo sapiens_hsa034202.40882043
15RNA transport_Homo sapiens_hsa030132.39296270
16Basal transcription factors_Homo sapiens_hsa030222.36476492
17Cell cycle_Homo sapiens_hsa041102.18356947
18RNA degradation_Homo sapiens_hsa030181.80518756
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.70682123
20One carbon pool by folate_Homo sapiens_hsa006701.70033115
21Alzheimers disease_Homo sapiens_hsa050101.69424849
22Propanoate metabolism_Homo sapiens_hsa006401.58221685
23Selenocompound metabolism_Homo sapiens_hsa004501.54849632
24Vitamin B6 metabolism_Homo sapiens_hsa007501.53994176
25Purine metabolism_Homo sapiens_hsa002301.46603306
26p53 signaling pathway_Homo sapiens_hsa041151.45115244
27Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.42278717
28mRNA surveillance pathway_Homo sapiens_hsa030151.34322294
29Phototransduction_Homo sapiens_hsa047441.33202788
30NF-kappa B signaling pathway_Homo sapiens_hsa040641.31847201
31Protein export_Homo sapiens_hsa030601.29952010
32Butanoate metabolism_Homo sapiens_hsa006501.25286349
33Primary immunodeficiency_Homo sapiens_hsa053401.24395779
34Epstein-Barr virus infection_Homo sapiens_hsa051691.22839136
35Herpes simplex infection_Homo sapiens_hsa051681.22029048
36Graft-versus-host disease_Homo sapiens_hsa053321.21974143
37Autoimmune thyroid disease_Homo sapiens_hsa053201.14303402
38Measles_Homo sapiens_hsa051621.09860796
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07675580
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05034669
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.03288313
42Maturity onset diabetes of the young_Homo sapiens_hsa049501.02078217
43Allograft rejection_Homo sapiens_hsa053301.01994721
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.98279544
45Cardiac muscle contraction_Homo sapiens_hsa042600.97589320
46Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91882059
47Antigen processing and presentation_Homo sapiens_hsa046120.89561852
48Nitrogen metabolism_Homo sapiens_hsa009100.88870163
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.88120212
50Arachidonic acid metabolism_Homo sapiens_hsa005900.80881143
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.79405215
52Systemic lupus erythematosus_Homo sapiens_hsa053220.79392647
53Hematopoietic cell lineage_Homo sapiens_hsa046400.78071606
54Peroxisome_Homo sapiens_hsa041460.76869036
55Fatty acid elongation_Homo sapiens_hsa000620.76125205
56Pyruvate metabolism_Homo sapiens_hsa006200.75205927
57Sulfur metabolism_Homo sapiens_hsa009200.74994107
58NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74185760
59Sphingolipid metabolism_Homo sapiens_hsa006000.74041976
60Asthma_Homo sapiens_hsa053100.73683898
61Tryptophan metabolism_Homo sapiens_hsa003800.73156295
62Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70501339
63Other glycan degradation_Homo sapiens_hsa005110.69009480
64Regulation of autophagy_Homo sapiens_hsa041400.68984998
65Huntingtons disease_Homo sapiens_hsa050160.65916481
66Legionellosis_Homo sapiens_hsa051340.65214591
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63911681
68Influenza A_Homo sapiens_hsa051640.61907893
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.61406802
70Caffeine metabolism_Homo sapiens_hsa002320.58926621
71Apoptosis_Homo sapiens_hsa042100.56164450
72Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54208092
73Folate biosynthesis_Homo sapiens_hsa007900.54046934
74Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.53498046
75Pentose phosphate pathway_Homo sapiens_hsa000300.52548127
76Oxidative phosphorylation_Homo sapiens_hsa001900.52353568
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51529661
78Steroid biosynthesis_Homo sapiens_hsa001000.51230016
79Viral carcinogenesis_Homo sapiens_hsa052030.50833219
80Leishmaniasis_Homo sapiens_hsa051400.49723642
81Rheumatoid arthritis_Homo sapiens_hsa053230.49635641
82Type I diabetes mellitus_Homo sapiens_hsa049400.49375255
83Ether lipid metabolism_Homo sapiens_hsa005650.49356150
84Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49205473
85Hepatitis B_Homo sapiens_hsa051610.48610479
86HTLV-I infection_Homo sapiens_hsa051660.48549264
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48291908
88Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47466878
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47395692
90Toll-like receptor signaling pathway_Homo sapiens_hsa046200.47336510
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45893669
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.45478496
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.45278584
94Circadian rhythm_Homo sapiens_hsa047100.43796265
95Linoleic acid metabolism_Homo sapiens_hsa005910.43193220
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.42733788
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42526772
98Malaria_Homo sapiens_hsa051440.40613437
99Notch signaling pathway_Homo sapiens_hsa043300.40585485
100MicroRNAs in cancer_Homo sapiens_hsa052060.40137879
101Parkinsons disease_Homo sapiens_hsa050120.39713396
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39531446
103Olfactory transduction_Homo sapiens_hsa047400.39465231
104Sulfur relay system_Homo sapiens_hsa041220.38906136
105beta-Alanine metabolism_Homo sapiens_hsa004100.37492336
106Small cell lung cancer_Homo sapiens_hsa052220.37457370
107Tuberculosis_Homo sapiens_hsa051520.34568693
108Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33994067
109T cell receptor signaling pathway_Homo sapiens_hsa046600.33429484
110Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33286503
111Vitamin digestion and absorption_Homo sapiens_hsa049770.31989326
112Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.31105199
113Collecting duct acid secretion_Homo sapiens_hsa049660.29395931
114Metabolic pathways_Homo sapiens_hsa011000.29085290
115Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28076695
116Taste transduction_Homo sapiens_hsa047420.25302006
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25075714
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.24812516
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.24770796
120Drug metabolism - other enzymes_Homo sapiens_hsa009830.24525624
121alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24242302
122Oocyte meiosis_Homo sapiens_hsa041140.23607222
123TGF-beta signaling pathway_Homo sapiens_hsa043500.22659321
124Viral myocarditis_Homo sapiens_hsa054160.22571523
125Primary bile acid biosynthesis_Homo sapiens_hsa001200.22478359
126Shigellosis_Homo sapiens_hsa051310.22087305
127Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.22005822
128Fatty acid metabolism_Homo sapiens_hsa012120.21923984
129Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.21509313
130Pertussis_Homo sapiens_hsa051330.20171003
131Chemical carcinogenesis_Homo sapiens_hsa052040.19404801
132Glutathione metabolism_Homo sapiens_hsa004800.18935257
133N-Glycan biosynthesis_Homo sapiens_hsa005100.18094826
134Glycerolipid metabolism_Homo sapiens_hsa005610.16552818
135Mineral absorption_Homo sapiens_hsa049780.12988131
136Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11847297
137Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.09992723
138Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.07971100
139Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.07146012
140Retinol metabolism_Homo sapiens_hsa008300.07070376

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