USF1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle cell fate commitment (GO:0042693)9.92364613
2tongue development (GO:0043586)5.66247259
3regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)5.50804643
4positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)5.50804643
5cartilage condensation (GO:0001502)5.31358320
6cell aggregation (GO:0098743)5.31358320
7protein complex biogenesis (GO:0070271)5.03651140
8mitochondrial respiratory chain complex I assembly (GO:0032981)4.57753992
9NADH dehydrogenase complex assembly (GO:0010257)4.57753992
10mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.57753992
11muscle cell cellular homeostasis (GO:0046716)4.57064282
12regulation of cilium movement (GO:0003352)4.53202850
13mitochondrial respiratory chain complex assembly (GO:0033108)4.32309970
14N-acetylglucosamine metabolic process (GO:0006044)4.23869675
15protein heterotetramerization (GO:0051290)4.21820258
16sodium-independent organic anion transport (GO:0043252)4.07662706
17regulation of sarcomere organization (GO:0060297)4.00228763
18lymphangiogenesis (GO:0001946)3.98194655
19UDP-N-acetylglucosamine metabolic process (GO:0006047)3.92488714
20detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.91718411
21positive regulation of vesicle fusion (GO:0031340)3.88061422
22negative regulation of mast cell activation (GO:0033004)3.80822588
23positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.79697111
24transepithelial transport (GO:0070633)3.78133099
25regulation of MHC class I biosynthetic process (GO:0045343)3.74168325
26DNA double-strand break processing (GO:0000729)3.72518194
27signal peptide processing (GO:0006465)3.71633286
28cellular potassium ion homeostasis (GO:0030007)3.70212949
29somitogenesis (GO:0001756)3.69062561
30oligodendrocyte differentiation (GO:0048709)3.68470197
31N-acetylneuraminate metabolic process (GO:0006054)3.68465093
32regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.68048706
33negative regulation of JUN kinase activity (GO:0043508)3.59123670
34negative regulation of nitric-oxide synthase activity (GO:0051001)3.56892979
35multicellular organismal movement (GO:0050879)3.56268299
36musculoskeletal movement (GO:0050881)3.56268299
37membrane budding (GO:0006900)3.55103121
38membrane raft organization (GO:0031579)3.51391809
39dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.49022874
40replication fork processing (GO:0031297)3.46310926
41regulation of translation in response to stress (GO:0043555)3.46169371
42positive regulation of protein autophosphorylation (GO:0031954)3.38392498
43segmentation (GO:0035282)3.33608438
44lung lobe morphogenesis (GO:0060463)3.33098113
45regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.31185373
46positive regulation of muscle hypertrophy (GO:0014742)3.27132739
47positive regulation of cardiac muscle hypertrophy (GO:0010613)3.27132739
48glucosamine-containing compound metabolic process (GO:1901071)3.25277934
49membrane assembly (GO:0071709)3.23862332
50skeletal muscle tissue development (GO:0007519)3.23289289
51rRNA catabolic process (GO:0016075)3.19646472
52recombinational repair (GO:0000725)3.19298758
53auditory receptor cell stereocilium organization (GO:0060088)3.19103364
54double-strand break repair via homologous recombination (GO:0000724)3.13766182
55histone H2A acetylation (GO:0043968)3.09288731
56defense response to Gram-negative bacterium (GO:0050829)3.03905174
57rRNA modification (GO:0000154)3.00765455
58natural killer cell activation involved in immune response (GO:0002323)2.97401832
59potassium ion import (GO:0010107)2.96876957
60activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.95827665
61positive regulation of cardiac muscle cell differentiation (GO:2000727)2.95205464
62detection of mechanical stimulus involved in sensory perception (GO:0050974)2.93619618
63endocardial cushion morphogenesis (GO:0003203)2.92182165
64nephron tubule formation (GO:0072079)2.88814846
65positive regulation of interleukin-8 secretion (GO:2000484)2.88038962
66regulation of T cell chemotaxis (GO:0010819)2.87066978
67positive regulation of T cell chemotaxis (GO:0010820)2.87066978
68mannosylation (GO:0097502)2.86512177
69positive regulation of actin filament depolymerization (GO:0030836)2.84085603
70ncRNA catabolic process (GO:0034661)2.81743271
71regulation of metalloenzyme activity (GO:0048552)2.78930389
72dopamine transport (GO:0015872)2.78243261
73lactate metabolic process (GO:0006089)2.77416195
74positive regulation of sodium ion transmembrane transport (GO:1902307)2.74047716
75limb bud formation (GO:0060174)2.72892401
76forebrain neuron development (GO:0021884)2.71701638
77anterograde synaptic vesicle transport (GO:0048490)2.70706601
78DNA demethylation (GO:0080111)2.70228486
79positive regulation of potassium ion transmembrane transport (GO:1901381)2.70074108
80cellular response to ethanol (GO:0071361)2.69098312
81regulation of nuclear cell cycle DNA replication (GO:0033262)2.68078349
82interleukin-6-mediated signaling pathway (GO:0070102)2.67995601
83regulation of protein glycosylation (GO:0060049)2.67766076
84regulation of interleukin-8 secretion (GO:2000482)2.67652923
85positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.67518328
86regulation of respiratory burst (GO:0060263)2.66305339
87negative regulation of execution phase of apoptosis (GO:1900118)2.64138802
88negative regulation of macroautophagy (GO:0016242)2.60838153
89positive regulation of cell size (GO:0045793)2.60186640
90regulation of alkaline phosphatase activity (GO:0010692)2.58988457
91glycosphingolipid biosynthetic process (GO:0006688)2.58964668
92proline transport (GO:0015824)2.57427515
93cytochrome complex assembly (GO:0017004)2.57070821
94positive regulation of lymphocyte apoptotic process (GO:0070230)2.56716720
95fucose catabolic process (GO:0019317)2.56635068
96L-fucose metabolic process (GO:0042354)2.56635068
97L-fucose catabolic process (GO:0042355)2.56635068
98activation of protein kinase B activity (GO:0032148)2.56548579
99neuromuscular synaptic transmission (GO:0007274)2.55976641
100sodium ion export (GO:0071436)2.55952995

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.44002008
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse4.65018595
3ZFP57_27257070_Chip-Seq_ESCs_Mouse3.04478294
4ZNF274_21170338_ChIP-Seq_K562_Hela3.02471899
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.84255342
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.79409320
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.63042272
8IGF1R_20145208_ChIP-Seq_DFB_Human2.38793619
9GBX2_23144817_ChIP-Seq_PC3_Human2.38771053
10AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.28584499
11ER_23166858_ChIP-Seq_MCF-7_Human2.12373563
12BCAT_22108803_ChIP-Seq_LS180_Human2.10066903
13VDR_22108803_ChIP-Seq_LS180_Human2.07348272
14CTBP2_25329375_ChIP-Seq_LNCAP_Human2.06220043
15ELK1_19687146_ChIP-ChIP_HELA_Human2.01627527
16P300_19829295_ChIP-Seq_ESCs_Human1.99815298
17FLI1_27457419_Chip-Seq_LIVER_Mouse1.93354808
18TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.92099464
19SMAD_19615063_ChIP-ChIP_OVARY_Human1.90370911
20SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.80265256
21OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.78975001
22PIAS1_25552417_ChIP-Seq_VCAP_Human1.73920320
23SMAD4_21799915_ChIP-Seq_A2780_Human1.71992507
24FUS_26573619_Chip-Seq_HEK293_Human1.71923653
25CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.68187368
26EWS_26573619_Chip-Seq_HEK293_Human1.63279412
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.58803870
28AR_25329375_ChIP-Seq_VCAP_Human1.57475038
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.57224502
30NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57085746
31CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.56621615
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.54638742
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.53485110
34TAF15_26573619_Chip-Seq_HEK293_Human1.51951927
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50748984
36SUZ12_27294783_Chip-Seq_NPCs_Mouse1.50741977
37CJUN_26792858_Chip-Seq_BT549_Human1.49023481
38CBP_20019798_ChIP-Seq_JUKART_Human1.45265056
39IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45265056
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44705853
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43501281
42MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42083759
43CDX2_22108803_ChIP-Seq_LS180_Human1.39392178
44BRD4_25478319_ChIP-Seq_HGPS_Human1.36625813
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.35627616
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35135150
47TCF4_23295773_ChIP-Seq_U87_Human1.34175200
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.33509276
49STAT3_23295773_ChIP-Seq_U87_Human1.33359889
50GABP_17652178_ChIP-ChIP_JURKAT_Human1.32051010
51EZH2_27294783_Chip-Seq_NPCs_Mouse1.30424290
52TCF4_22108803_ChIP-Seq_LS180_Human1.30215744
53ELK1_22589737_ChIP-Seq_MCF10A_Human1.30030044
54EGR1_23403033_ChIP-Seq_LIVER_Mouse1.29602333
55SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.29058837
56CRX_20693478_ChIP-Seq_RETINA_Mouse1.27987563
57MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27753233
58POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27057131
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27057131
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.26383554
61RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.26035794
62RXR_22108803_ChIP-Seq_LS180_Human1.25405639
63HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.24979007
64FLI1_21867929_ChIP-Seq_TH2_Mouse1.24010337
65EST1_17652178_ChIP-ChIP_JURKAT_Human1.23588531
66NANOG_18555785_Chip-Seq_ESCs_Mouse1.22585334
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20042961
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18980550
69EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18620437
70CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.18270994
71NFE2_27457419_Chip-Seq_LIVER_Mouse1.17950427
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.15074025
73NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.15074025
74P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12477184
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.12431608
76FOXM1_26456572_ChIP-Seq_MCF-7_Human1.12374540
77RUNX2_22187159_ChIP-Seq_PCA_Human1.11944130
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10917826
79SOX2_19829295_ChIP-Seq_ESCs_Human1.10275443
80NANOG_19829295_ChIP-Seq_ESCs_Human1.10275443
81EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.08861459
82P53_22387025_ChIP-Seq_ESCs_Mouse1.07478461
83KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.07010232
84TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.06889513
85TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06791091
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05627818
87TP53_22573176_ChIP-Seq_HFKS_Human1.05062053
88SALL4_22934838_ChIP-ChIP_CD34+_Human1.04564814
89ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04363717
90TP53_18474530_ChIP-ChIP_U2OS_Human1.04281262
91TAL1_26923725_Chip-Seq_HPCs_Mouse1.04280587
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.03364627
93OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03175585
94SUZ12_18555785_Chip-Seq_ESCs_Mouse1.03092139
95NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03082450
96PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02882092
97EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.01239951
98SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.00543944
99SMAD4_21741376_ChIP-Seq_EPCs_Human0.99787828
100AR_20517297_ChIP-Seq_VCAP_Human0.99413701

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002234_abnormal_pharynx_morphology8.11261188
2MP0003300_gastrointestinal_ulcer4.93282992
3MP0003950_abnormal_plasma_membrane4.32341930
4MP0003191_abnormal_cellular_cholesterol3.51356498
5MP0006054_spinal_hemorrhage3.38053310
6MP0000569_abnormal_digit_pigmentation3.37354132
7MP0000750_abnormal_muscle_regeneration3.09855434
8MP0009780_abnormal_chondrocyte_physiolo2.85142314
9MP0001853_heart_inflammation2.24383609
10MP0005360_urolithiasis2.13133656
11MP0005379_endocrine/exocrine_gland_phen1.98291066
12MP0002108_abnormal_muscle_morphology1.97178721
13MP0000013_abnormal_adipose_tissue1.95425291
14MP0010368_abnormal_lymphatic_system1.85067663
15MP0004885_abnormal_endolymph1.84618565
16MP0005423_abnormal_somatic_nervous1.82194209
17MP0008875_abnormal_xenobiotic_pharmacok1.81881707
18MP0006072_abnormal_retinal_apoptosis1.80256443
19MP0005310_abnormal_salivary_gland1.78225492
20MP0000733_abnormal_muscle_development1.76901469
21MP0005670_abnormal_white_adipose1.73039633
22MP0003787_abnormal_imprinting1.70815933
23MP0001984_abnormal_olfaction1.64069341
24MP0002282_abnormal_trachea_morphology1.62266855
25MP0003868_abnormal_feces_composition1.59804912
26MP0005645_abnormal_hypothalamus_physiol1.59439941
27MP0001529_abnormal_vocalization1.55125830
28MP0009764_decreased_sensitivity_to1.51757444
29MP0004883_abnormal_blood_vessel1.51684048
30MP0002163_abnormal_gland_morphology1.48079204
31MP0003866_abnormal_defecation1.44552300
32MP0003137_abnormal_impulse_conducting1.44247941
33MP0000538_abnormal_urinary_bladder1.40299817
34MP0003011_delayed_dark_adaptation1.37707259
35MP0002736_abnormal_nociception_after1.37501192
36MP0000372_irregular_coat_pigmentation1.36174426
37MP0005253_abnormal_eye_physiology1.34411590
38MP0002272_abnormal_nervous_system1.25775723
39MP0001485_abnormal_pinna_reflex1.22801761
40MP0002138_abnormal_hepatobiliary_system1.22118570
41MP0010386_abnormal_urinary_bladder1.12624156
42MP0000516_abnormal_urinary_system1.12543201
43MP0005367_renal/urinary_system_phenotyp1.12543201
44MP0002837_dystrophic_cardiac_calcinosis1.11433180
45MP0002932_abnormal_joint_morphology1.09269423
46MP0009765_abnormal_xenobiotic_induced1.08505996
47MP0002734_abnormal_mechanical_nocicepti1.08453160
48MP0003959_abnormal_lean_body1.08206411
49MP0008872_abnormal_physiological_respon1.07283384
50MP0009745_abnormal_behavioral_response1.02865385
51MP0003279_aneurysm1.01490852
52MP0004270_analgesia1.00639606
53MP0005084_abnormal_gallbladder_morpholo0.98878671
54MP0004142_abnormal_muscle_tone0.98524744
55MP0000465_gastrointestinal_hemorrhage0.95889326
56MP0003646_muscle_fatigue0.95417385
57MP0001486_abnormal_startle_reflex0.93663350
58MP0008058_abnormal_DNA_repair0.91093841
59MP0003633_abnormal_nervous_system0.90194120
60MP0003045_fibrosis0.85506155
61MP0001968_abnormal_touch/_nociception0.84581975
62MP0005166_decreased_susceptibility_to0.82902598
63MP0005623_abnormal_meninges_morphology0.81712774
64MP0005220_abnormal_exocrine_pancreas0.80652860
65MP0002332_abnormal_exercise_endurance0.78783476
66MP0000015_abnormal_ear_pigmentation0.77473114
67MP0005174_abnormal_tail_pigmentation0.73876665
68MP0008775_abnormal_heart_ventricle0.72941909
69MP0001879_abnormal_lymphatic_vessel0.71157236
70MP0002139_abnormal_hepatobiliary_system0.70926929
71MP0003755_abnormal_palate_morphology0.69407078
72MP0003186_abnormal_redox_activity0.68251887
73MP0005164_abnormal_response_to0.66743968
74MP0001873_stomach_inflammation0.65875945
75MP0010234_abnormal_vibrissa_follicle0.65789534
76MP0005595_abnormal_vascular_smooth0.64618750
77MP0005389_reproductive_system_phenotype0.64530800
78MP0005023_abnormal_wound_healing0.63852034
79MP0002102_abnormal_ear_morphology0.63508533
80MP0000358_abnormal_cell_content/0.62973587
81MP0002733_abnormal_thermal_nociception0.62362177
82MP0010094_abnormal_chromosome_stability0.62137848
83MP0002160_abnormal_reproductive_system0.61859608
84MP0005452_abnormal_adipose_tissue0.60323643
85MP0002168_other_aberrant_phenotype0.60017684
86MP0000343_altered_response_to0.59341400
87MP0003121_genomic_imprinting0.59182434
88MP0001915_intracranial_hemorrhage0.58701245
89MP0002106_abnormal_muscle_physiology0.58222945
90MP0005332_abnormal_amino_acid0.55730794
91MP0001970_abnormal_pain_threshold0.54812649
92MP0008438_abnormal_cutaneous_collagen0.54574921
93MP0000762_abnormal_tongue_morphology0.54484203
94MP0001764_abnormal_homeostasis0.54130619
95MP0004215_abnormal_myocardial_fiber0.54024923
96MP0003252_abnormal_bile_duct0.52570668
97MP0005646_abnormal_pituitary_gland0.52354341
98MP0001542_abnormal_bone_strength0.52288682
99MP0002972_abnormal_cardiac_muscle0.52036715
100MP0000759_abnormal_skeletal_muscle0.51642243

Predicted human phenotypes

RankGene SetZ-score
1Amniotic constriction ring (HP:0009775)6.55502305
2Abnormality of placental membranes (HP:0011409)6.55502305
3Popliteal pterygium (HP:0009756)6.08663954
4Type 2 muscle fiber atrophy (HP:0003554)5.62462211
5Muscle fiber atrophy (HP:0100295)4.79570722
6Fetal akinesia sequence (HP:0001989)4.61719408
7Abnormality of the neuromuscular junction (HP:0003398)4.10919534
8Fatigable weakness (HP:0003473)4.10919534
9Abnormal hair whorl (HP:0010721)3.79357206
10Intestinal atresia (HP:0011100)3.57353998
11Aplasia of the musculature (HP:0100854)3.56730141
12Weak cry (HP:0001612)3.29583453
13Cystic hygroma (HP:0000476)3.20344188
14Aplasia/Hypoplasia involving the musculature (HP:0001460)3.02087600
15Hypoproteinemia (HP:0003075)2.98026299
16True hermaphroditism (HP:0010459)2.96053619
17Sex reversal (HP:0012245)2.95434333
18Abnormal sex determination (HP:0012244)2.95434333
19Akinesia (HP:0002304)2.73065856
20Atonic seizures (HP:0010819)2.72257407
21Volvulus (HP:0002580)2.68626583
22Gowers sign (HP:0003391)2.65275746
23Thin ribs (HP:0000883)2.62723763
24Poor eye contact (HP:0000817)2.61110729
25Aqueductal stenosis (HP:0002410)2.60680440
26Pancreatic cysts (HP:0001737)2.54606587
27Glucose intolerance (HP:0000833)2.51847038
28Long clavicles (HP:0000890)2.51252752
29Malignant hyperthermia (HP:0002047)2.48085362
30Acute necrotizing encephalopathy (HP:0006965)2.47168813
31Easy fatigability (HP:0003388)2.43895633
32Inability to walk (HP:0002540)2.40399385
33Progressive macrocephaly (HP:0004481)2.40035867
34Abnormalities of placenta or umbilical cord (HP:0001194)2.39188819
35Neoplasm of the adrenal cortex (HP:0100641)2.36807093
36Methylmalonic acidemia (HP:0002912)2.35465901
37Hemiparesis (HP:0001269)2.35379170
38Acute encephalopathy (HP:0006846)2.35297322
39Hyperventilation (HP:0002883)2.34931181
40Anencephaly (HP:0002323)2.34604167
41Curly hair (HP:0002212)2.27063100
42Dialeptic seizures (HP:0011146)2.24822650
43Pendular nystagmus (HP:0012043)2.21312393
44Type I transferrin isoform profile (HP:0003642)2.20626675
45Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.19758083
46Gastrointestinal atresia (HP:0002589)2.17710377
47Hypoplastic iliac wings (HP:0002866)2.16613769
48Nephronophthisis (HP:0000090)2.10590525
49Pterygium (HP:0001059)2.09754294
50Meningioma (HP:0002858)2.09746162
51Short middle phalanx of the 5th finger (HP:0004220)2.08137054
52Fair hair (HP:0002286)2.07906678
53Absence seizures (HP:0002121)2.00804597
54Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.00659595
55Abnormal protein N-linked glycosylation (HP:0012347)2.00659595
56Abnormal protein glycosylation (HP:0012346)2.00659595
57Abnormal glycosylation (HP:0012345)2.00659595
58Small hand (HP:0200055)1.99697554
59Secondary amenorrhea (HP:0000869)1.94271675
60Esophageal atresia (HP:0002032)1.93268159
61Chronic hepatic failure (HP:0100626)1.92950984
62Abnormality of the renal medulla (HP:0100957)1.91618756
63Neoplasm of the oral cavity (HP:0100649)1.91045630
64Pancreatic fibrosis (HP:0100732)1.90915693
65CNS demyelination (HP:0007305)1.90102552
66Mesomelia (HP:0003027)1.89442169
67Hypobetalipoproteinemia (HP:0003563)1.88911428
68Abnormality of the antihelix (HP:0009738)1.87792276
69Poor suck (HP:0002033)1.86583304
70Fibular aplasia (HP:0002990)1.85801341
71Progressive inability to walk (HP:0002505)1.85563111
72Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.84740608
73Focal motor seizures (HP:0011153)1.84399811
74Decreased muscle mass (HP:0003199)1.84211017
75Sensory axonal neuropathy (HP:0003390)1.82969063
76Increased corneal curvature (HP:0100692)1.82356837
77Keratoconus (HP:0000563)1.82356837
78Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.82069065
79Depressed nasal tip (HP:0000437)1.81515955
80Diminished movement (HP:0002374)1.79904434
81Occipital encephalocele (HP:0002085)1.79630720
82Irregular vertebral endplates (HP:0003301)1.79437834
83Drooling (HP:0002307)1.79221593
84Hypoplastic heart (HP:0001961)1.78082934
85Thyroid carcinoma (HP:0002890)1.77819056
86Mitochondrial inheritance (HP:0001427)1.76763019
87Abnormal mitochondria in muscle tissue (HP:0008316)1.76174256
88Abnormal glucose tolerance (HP:0001952)1.75522227
89Broad alveolar ridges (HP:0000187)1.74982833
90Oligodactyly (hands) (HP:0001180)1.72897925
91Chorioretinal atrophy (HP:0000533)1.72365415
92Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.72275733
93Breast carcinoma (HP:0003002)1.70976461
94Stomach cancer (HP:0012126)1.70580181
95Exocrine pancreatic insufficiency (HP:0001738)1.68332163
96Methylmalonic aciduria (HP:0012120)1.66609560
97Hypoalbuminemia (HP:0003073)1.66458992
98Abnormal albumin level (HP:0012116)1.66458992
99Reduced subcutaneous adipose tissue (HP:0003758)1.66216441
100Male infertility (HP:0003251)1.65742371

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MUSK4.77730377
2EIF2AK33.79650205
3NUAK13.60043173
4PRKD33.45952515
5STK393.31946103
6CCNB13.21789737
7CASK3.03497726
8STK163.00786111
9VRK22.97584958
10EIF2AK12.80143651
11OXSR12.73453947
12FRK2.65844200
13BRSK22.61102785
14MAPK132.42513116
15TAF12.38948290
16MST42.24300489
17LIMK11.80016408
18MKNK21.71514729
19MARK11.70561050
20MAP4K21.67905555
21WNK31.59111898
22GRK11.44998517
23PLK21.44268955
24PAK31.43468361
25ZAK1.39339384
26TRIM281.26527986
27ERBB31.18476282
28BRSK11.17147572
29MAP3K121.13860946
30CAMKK21.06768269
31MAP3K21.04222635
32FER1.03635305
33VRK11.00017363
34BMPR1B0.92395720
35WEE10.90498782
36NTRK30.87196847
37CSNK1G10.84301809
38CSNK1G30.83820927
39CSNK1A1L0.83257682
40BCR0.81869380
41PLK30.80576707
42PRKCE0.80535498
43EIF2AK20.79119371
44ROCK10.77252055
45MYLK0.75870711
46PKN10.71530390
47NME10.67047834
48DYRK20.65766264
49MKNK10.62060407
50RAF10.61725195
51PRKD20.61190774
52DAPK10.58780241
53MAPKAPK50.58763749
54DMPK0.58740962
55SRPK10.57421985
56CSNK1G20.57251999
57GSK3A0.55294075
58GRK50.54459651
59MELK0.54267076
60FGFR20.53829403
61SMG10.53399236
62MAP3K40.52268015
63DYRK1A0.51837782
64TAOK30.51837623
65CDK90.51196084
66PIK3CG0.50139620
67ADRBK20.49157021
68PHKG20.44206392
69PHKG10.44206392
70LMTK20.43972157
71CAMK2D0.43860533
72KSR10.43313718
73CDK80.42417890
74PRKCG0.42229348
75NTRK20.40441651
76INSRR0.38656791
77PRKCQ0.38564872
78PRKDC0.36897842
79ROCK20.36540650
80SGK20.34548504
81STK110.32635714
82ERBB20.32592924
83MAP3K140.31850310
84ILK0.31495227
85PRKCH0.31426997
86STK38L0.29469082
87IKBKB0.29221505
88SIK30.28726661
89CSNK1A10.28723667
90IGF1R0.28615085
91CSNK2A20.27496602
92PRKCI0.27295970
93STK40.27246433
94CHEK20.25069770
95CHUK0.24782262
96MAPK70.23696894
97PRKACA0.22975532
98ABL10.22819178
99WNK10.22367437
100ADRBK10.22081476

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030605.57441200
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.63791792
3Proteasome_Homo sapiens_hsa030503.36449740
4Propanoate metabolism_Homo sapiens_hsa006402.99228075
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.61375301
6Non-homologous end-joining_Homo sapiens_hsa034502.59583641
7Vitamin B6 metabolism_Homo sapiens_hsa007502.55770830
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.18825111
9Folate biosynthesis_Homo sapiens_hsa007902.17366401
10Steroid biosynthesis_Homo sapiens_hsa001002.09835115
11Butanoate metabolism_Homo sapiens_hsa006502.02394636
12Mineral absorption_Homo sapiens_hsa049781.97575141
13RNA polymerase_Homo sapiens_hsa030201.90739425
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.75206628
15Sulfur metabolism_Homo sapiens_hsa009201.59153142
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.54367924
17Oxidative phosphorylation_Homo sapiens_hsa001901.50812612
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43659043
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.43218225
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41770844
21Salivary secretion_Homo sapiens_hsa049701.39148619
22Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.36876578
23Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.29437052
24Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25779329
25Parkinsons disease_Homo sapiens_hsa050121.24019435
26Nicotine addiction_Homo sapiens_hsa050331.23302971
27Pancreatic secretion_Homo sapiens_hsa049721.20464386
28Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.18756312
29Melanoma_Homo sapiens_hsa052181.16750710
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.15783684
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13638352
32Fatty acid biosynthesis_Homo sapiens_hsa000611.11223276
33Selenocompound metabolism_Homo sapiens_hsa004501.09492025
34PPAR signaling pathway_Homo sapiens_hsa033201.04564077
35Fatty acid elongation_Homo sapiens_hsa000621.01339621
36Fanconi anemia pathway_Homo sapiens_hsa034600.98160607
37Sulfur relay system_Homo sapiens_hsa041220.97666035
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.95969176
39GABAergic synapse_Homo sapiens_hsa047270.95156532
40SNARE interactions in vesicular transport_Homo sapiens_hsa041300.95084473
41Tryptophan metabolism_Homo sapiens_hsa003800.95037662
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.93450304
43Fatty acid metabolism_Homo sapiens_hsa012120.92363486
44Circadian rhythm_Homo sapiens_hsa047100.91478103
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87326959
46Cardiac muscle contraction_Homo sapiens_hsa042600.86675466
47Pyruvate metabolism_Homo sapiens_hsa006200.86197442
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86006557
49Huntingtons disease_Homo sapiens_hsa050160.85002306
50beta-Alanine metabolism_Homo sapiens_hsa004100.80954599
51Thyroid hormone synthesis_Homo sapiens_hsa049180.77803834
52Alzheimers disease_Homo sapiens_hsa050100.72581905
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72374392
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71182967
55Homologous recombination_Homo sapiens_hsa034400.70972614
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67923170
57Gap junction_Homo sapiens_hsa045400.67378288
58Basal transcription factors_Homo sapiens_hsa030220.66989045
59Fatty acid degradation_Homo sapiens_hsa000710.66463604
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61113348
61RNA degradation_Homo sapiens_hsa030180.60288530
62Insulin secretion_Homo sapiens_hsa049110.57032183
63Peroxisome_Homo sapiens_hsa041460.55644522
64Bile secretion_Homo sapiens_hsa049760.55443889
65Wnt signaling pathway_Homo sapiens_hsa043100.54576036
66Nitrogen metabolism_Homo sapiens_hsa009100.52886916
67Gastric acid secretion_Homo sapiens_hsa049710.52546002
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52149054
69Glycerolipid metabolism_Homo sapiens_hsa005610.52018726
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51490398
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50463884
72Sphingolipid metabolism_Homo sapiens_hsa006000.50404666
73Dorso-ventral axis formation_Homo sapiens_hsa043200.50126430
74Ether lipid metabolism_Homo sapiens_hsa005650.49821031
75Prostate cancer_Homo sapiens_hsa052150.49796424
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48315555
77Linoleic acid metabolism_Homo sapiens_hsa005910.45926523
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44577756
79Vibrio cholerae infection_Homo sapiens_hsa051100.43611256
80Chemical carcinogenesis_Homo sapiens_hsa052040.43216243
81Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.43100883
82Complement and coagulation cascades_Homo sapiens_hsa046100.41038531
83cGMP-PKG signaling pathway_Homo sapiens_hsa040220.39820979
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36875230
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36293003
86Hedgehog signaling pathway_Homo sapiens_hsa043400.36024925
87Serotonergic synapse_Homo sapiens_hsa047260.33736751
88Glutamatergic synapse_Homo sapiens_hsa047240.32979879
89Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32152494
90Taste transduction_Homo sapiens_hsa047420.31686997
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.31255381
92Histidine metabolism_Homo sapiens_hsa003400.31246366
93Metabolic pathways_Homo sapiens_hsa011000.30841687
94Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.29673042
95Purine metabolism_Homo sapiens_hsa002300.29141868
96Pyrimidine metabolism_Homo sapiens_hsa002400.28954513
97Phototransduction_Homo sapiens_hsa047440.28654505
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28177700
99Morphine addiction_Homo sapiens_hsa050320.26792110
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26585778

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