UNCX

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.39597124
2axonal fasciculation (GO:0007413)6.32583121
3polyketide metabolic process (GO:0030638)6.16037262
4doxorubicin metabolic process (GO:0044598)6.16037262
5daunorubicin metabolic process (GO:0044597)6.16037262
6neurofilament cytoskeleton organization (GO:0060052)5.80123760
7tachykinin receptor signaling pathway (GO:0007217)5.71760338
8locomotory exploration behavior (GO:0035641)5.49588288
9establishment of mitochondrion localization, microtubule-mediated (GO:0034643)5.18398060
10mitochondrion transport along microtubule (GO:0047497)5.18398060
11establishment of mitochondrion localization (GO:0051654)5.09356675
12positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.90996669
13neuron recognition (GO:0008038)4.75546769
14presynaptic membrane organization (GO:0097090)4.68042759
15nucleobase catabolic process (GO:0046113)4.59435144
16embryonic retina morphogenesis in camera-type eye (GO:0060059)4.51325564
17* forebrain neuron differentiation (GO:0021879)4.44264794
18cranial nerve morphogenesis (GO:0021602)4.40190766
19axon ensheathment in central nervous system (GO:0032291)4.33631638
20central nervous system myelination (GO:0022010)4.33631638
21spinal cord association neuron differentiation (GO:0021527)4.32262490
22uterus development (GO:0060065)4.31887608
23parturition (GO:0007567)4.26299121
24central nervous system projection neuron axonogenesis (GO:0021952)4.25237248
25cerebellar Purkinje cell differentiation (GO:0021702)4.20936753
26positive regulation of gastrulation (GO:2000543)4.17345673
27neuronal ion channel clustering (GO:0045161)4.14915003
28adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.14634178
29urogenital system development (GO:0001655)4.13475821
30neuron cell-cell adhesion (GO:0007158)4.08978883
31synaptic transmission, dopaminergic (GO:0001963)4.06389295
32exploration behavior (GO:0035640)3.98208042
33axon extension (GO:0048675)3.96570802
34negative regulation of neurotransmitter secretion (GO:0046929)3.92781163
35body morphogenesis (GO:0010171)3.90519755
36aminoglycoside antibiotic metabolic process (GO:0030647)3.90326975
37negative regulation of osteoblast proliferation (GO:0033689)3.85829601
38negative regulation of axon guidance (GO:1902668)3.84297095
39behavioral response to ethanol (GO:0048149)3.82375838
40cell migration in hindbrain (GO:0021535)3.79529003
41synaptic vesicle maturation (GO:0016188)3.72273852
42head development (GO:0060322)3.69872975
43positive regulation of growth hormone secretion (GO:0060124)3.68407808
44regulation of synapse maturation (GO:0090128)3.67570135
45regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.62309634
46positive regulation of synapse assembly (GO:0051965)3.54294786
47cell proliferation in forebrain (GO:0021846)3.52008613
48positive regulation of male gonad development (GO:2000020)3.51528009
49positive regulation of synapse maturation (GO:0090129)3.51277613
50regulation of synapse assembly (GO:0051963)3.51234577
51ganglion development (GO:0061548)3.49344067
52substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.47885972
53substrate-independent telencephalic tangential migration (GO:0021826)3.47885972
54transmission of nerve impulse (GO:0019226)3.44878254
55embryonic body morphogenesis (GO:0010172)3.44785438
56regulation of synapse structural plasticity (GO:0051823)3.39887295
57regulation of cilium movement (GO:0003352)3.38775274
58synapse assembly (GO:0007416)3.38257501
59negative regulation of axon extension involved in axon guidance (GO:0048843)3.37740263
60short-term memory (GO:0007614)3.36962204
61behavioral response to nicotine (GO:0035095)3.35535192
62cerebellum development (GO:0021549)3.34072961
63regulation of microtubule-based movement (GO:0060632)3.31442469
64neuron projection extension (GO:1990138)3.29791130
65sensory perception of smell (GO:0007608)3.29627549
66midbrain development (GO:0030901)3.24635964
67positive regulation of action potential (GO:0045760)3.24476748
68vocalization behavior (GO:0071625)3.22761916
69central nervous system neuron axonogenesis (GO:0021955)3.20960476
70dopamine receptor signaling pathway (GO:0007212)3.20641271
71negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.19802781
72positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.19277480
73hippocampus development (GO:0021766)3.17233967
74regulation of male gonad development (GO:2000018)3.17043692
75opioid receptor signaling pathway (GO:0038003)3.16798341
76negative regulation of catecholamine secretion (GO:0033604)3.15501154
77neuron migration (GO:0001764)3.15407610
78negative regulation of microtubule polymerization (GO:0031115)3.14536849
79dendritic spine morphogenesis (GO:0060997)3.12010357
80regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.09829587
81regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.09829587
82facial nerve structural organization (GO:0021612)3.09572206
83atrial cardiac muscle cell action potential (GO:0086014)3.07519904
84glucocorticoid biosynthetic process (GO:0006704)3.07258268
85membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.07196400
86regulation of chromatin binding (GO:0035561)3.06157176
87olfactory bulb development (GO:0021772)3.05920202
88adult walking behavior (GO:0007628)3.05597403
89microtubule bundle formation (GO:0001578)3.02758307
90behavioral response to cocaine (GO:0048148)3.02243275
91regulation of synapse organization (GO:0050807)3.01452577
92cerebellar granule cell differentiation (GO:0021707)3.01348254
93mechanosensory behavior (GO:0007638)3.01116683
94cranial nerve structural organization (GO:0021604)3.00807608
95cell differentiation in hindbrain (GO:0021533)2.98293016
96genetic imprinting (GO:0071514)2.98116367
97auditory behavior (GO:0031223)2.97001323
98endoderm formation (GO:0001706)2.96794564
99dopaminergic neuron differentiation (GO:0071542)2.96229124
100ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.95715846
101mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.95067762
102retinal ganglion cell axon guidance (GO:0031290)2.93024115
103regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.91758665
104negative regulation of catenin import into nucleus (GO:0035414)2.88652531
105response to muscle activity (GO:0014850)2.88538561
106regulation of short-term neuronal synaptic plasticity (GO:0048172)2.88450734
107semaphorin-plexin signaling pathway (GO:0071526)2.88402230
108regulation of mesenchymal cell apoptotic process (GO:2001053)2.88320246
109spinal cord development (GO:0021510)2.88242245
110establishment or maintenance of monopolar cell polarity (GO:0061339)2.87712525
111establishment of monopolar cell polarity (GO:0061162)2.87712525
112negative regulation of axon extension (GO:0030517)2.87105238
113synaptic vesicle endocytosis (GO:0048488)2.85977157
114negative regulation of transcription regulatory region DNA binding (GO:2000678)2.84874939
115cell differentiation in spinal cord (GO:0021515)2.82611000
116response to inactivity (GO:0014854)2.82039673
117neuron maturation (GO:0042551)2.81119258
118response to histamine (GO:0034776)2.80186837
119regulation of neuron migration (GO:2001222)2.79992705
120regulation of growth hormone secretion (GO:0060123)2.79344095
121striatum development (GO:0021756)2.78429164
122inner ear receptor stereocilium organization (GO:0060122)2.77087399
123camera-type eye morphogenesis (GO:0048593)2.76373740
124hypothalamus development (GO:0021854)2.76207911
125regulation of glutamate receptor signaling pathway (GO:1900449)2.75380142
126mitochondrion localization (GO:0051646)2.73457843
127adult feeding behavior (GO:0008343)2.73308057
128regulation of action potential (GO:0098900)2.73165706
129dosage compensation (GO:0007549)2.73075038
130regulation of non-canonical Wnt signaling pathway (GO:2000050)2.72188356
131synaptic transmission, cholinergic (GO:0007271)2.72079656
132postsynaptic membrane organization (GO:0001941)2.70763548
133negative regulation of response to food (GO:0032096)2.70562517
134negative regulation of appetite (GO:0032099)2.70562517
135regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.68813976
136glomerulus development (GO:0032835)2.68158119
137regulation of membrane repolarization (GO:0060306)2.68121765
138protein polyglutamylation (GO:0018095)2.67372350
139generation of neurons (GO:0048699)2.67371153
140axoneme assembly (GO:0035082)2.67332206
141response to gravity (GO:0009629)2.65950539
142primitive streak formation (GO:0090009)2.64163196
143central nervous system neuron development (GO:0021954)2.64064385
144phosphorelay signal transduction system (GO:0000160)2.63637928
145dendrite morphogenesis (GO:0048813)2.63582572
146response to auditory stimulus (GO:0010996)2.63394106
147negative regulation of neurotransmitter transport (GO:0051589)2.63294998
148nucleosome disassembly (GO:0006337)2.61895378
149protein-DNA complex disassembly (GO:0032986)2.61895378
150regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.61787762
151paraxial mesoderm development (GO:0048339)2.61059099
152membrane repolarization during action potential (GO:0086011)2.60298488
153establishment of nucleus localization (GO:0040023)2.59858225
154G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.59081492
155layer formation in cerebral cortex (GO:0021819)2.58926646
156neuron projection extension involved in neuron projection guidance (GO:1902284)2.58047411
157axon extension involved in axon guidance (GO:0048846)2.58047411
158protein localization to synapse (GO:0035418)2.58039689
159regulation of axon guidance (GO:1902667)2.57230319
160protein localization to microtubule (GO:0035372)2.55974623
161kidney morphogenesis (GO:0060993)2.55502070
162* central nervous system neuron differentiation (GO:0021953)2.52207293
163calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.51746949
164response to pheromone (GO:0019236)11.3515925

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.01189956
2* EZH2_27304074_Chip-Seq_ESCs_Mouse3.41240336
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.30524457
4* EED_16625203_ChIP-ChIP_MESCs_Mouse3.23727705
5GBX2_23144817_ChIP-Seq_PC3_Human3.23242655
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.16396604
7* BMI1_23680149_ChIP-Seq_NPCS_Mouse3.11671489
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.89106709
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.89106709
10NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.87434513
11* CBX2_27304074_Chip-Seq_ESCs_Mouse2.83878519
12* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.78062197
13* PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.74436163
14* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.72753893
15CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.72257935
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.72126488
17* RNF2_27304074_Chip-Seq_ESCs_Mouse2.68385280
18* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.67161095
19* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.60172140
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.54439838
21* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.52257293
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38051539
23* RNF2_27304074_Chip-Seq_NSC_Mouse2.35505668
24* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.33135342
25TP63_19390658_ChIP-ChIP_HaCaT_Human2.14972325
26* RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.14447567
27REST_21632747_ChIP-Seq_MESCs_Mouse2.11631719
28POU5F1_16153702_ChIP-ChIP_HESCs_Human2.03457770
29* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.97428945
30IGF1R_20145208_ChIP-Seq_DFB_Human1.93402753
31* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.86574500
32CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84916065
33* RING1B_27294783_Chip-Seq_ESCs_Mouse1.84553715
34DROSHA_22980978_ChIP-Seq_HELA_Human1.83006548
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.75494519
36* RING1B_27294783_Chip-Seq_NPCs_Mouse1.72330974
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70646997
38* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.68727382
39CTCF_27219007_Chip-Seq_Bcells_Human1.67508642
40TAF15_26573619_Chip-Seq_HEK293_Human1.66035438
41* TP53_20018659_ChIP-ChIP_R1E_Mouse1.65014941
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61941321
43* REST_18959480_ChIP-ChIP_MESCs_Mouse1.57351891
44BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.55759858
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.53750787
46IKZF1_21737484_ChIP-ChIP_HCT116_Human1.52542070
47TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51379033
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.51379033
49RARB_27405468_Chip-Seq_BRAIN_Mouse1.47554230
50RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42308839
51* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40594084
52* KDM2B_26808549_Chip-Seq_K562_Human1.40047479
53* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.39751083
54P300_19829295_ChIP-Seq_ESCs_Human1.33635046
55IRF1_19129219_ChIP-ChIP_H3396_Human1.33262654
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.25777464
57CTBP1_25329375_ChIP-Seq_LNCAP_Human1.24360479
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23072228
59CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.22322653
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20935109
61CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.19542097
62HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18464437
63P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17229249
64* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15718943
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.13925975
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11997395
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.11288965
68ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.09273007
69RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08870751
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.07710716
71SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.05623265
72GATA1_26923725_Chip-Seq_HPCs_Mouse1.05592564
73AR_21572438_ChIP-Seq_LNCaP_Human1.04608735
74GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04587230
75STAT6_21828071_ChIP-Seq_BEAS2B_Human1.04293388
76MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.04220600
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.01425991
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.99981471
79SOX2_16153702_ChIP-ChIP_HESCs_Human0.98326414
80GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98284011
81MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.96532376
82ETV2_25802403_ChIP-Seq_MESCs_Mouse0.96022339
83ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95537616
84EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94211504
85SMAD4_21799915_ChIP-Seq_A2780_Human0.93653561
86STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93596857
87* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.93542468
88ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.92677624
89* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92138145
90* NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92026083
91THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91275008
92RUNX2_22187159_ChIP-Seq_PCA_Human0.91212870
93NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90723187
94ARNT_22903824_ChIP-Seq_MCF-7_Human0.90019977
95KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89993118
96RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88875691
97CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88402141
98ELK4_26923725_Chip-Seq_MESODERM_Mouse0.88299642
99VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88086787
100TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.87579197
101VDR_22108803_ChIP-Seq_LS180_Human0.85906770
102WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.85322953
103FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.85215456
104SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84334272
105POU3F2_20337985_ChIP-ChIP_501MEL_Human0.84238219
106SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.84030823
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.83864761
108AR_19668381_ChIP-Seq_PC3_Human0.83847264
109MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.83540703
110TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83025895
111* OCT4_19829295_ChIP-Seq_ESCs_Human0.81763106
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.81358790
113NANOG_18555785_Chip-Seq_ESCs_Mouse0.81027802
114POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.80142991
115* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.79062901
116SMAD3_21741376_ChIP-Seq_ESCs_Human0.78759158
117YAP1_20516196_ChIP-Seq_MESCs_Mouse0.78303399
118ISL1_27105846_Chip-Seq_CPCs_Mouse0.78124702
119ZNF274_21170338_ChIP-Seq_K562_Hela0.78039310
120SOX2_21211035_ChIP-Seq_LN229_Gbm0.77922344
121AR_25329375_ChIP-Seq_VCAP_Human0.77643666
122SOX9_26525672_Chip-Seq_HEART_Mouse0.77048205
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.76806124
124NCOR_22424771_ChIP-Seq_293T_Human0.76107105
125REST_19997604_ChIP-ChIP_NEURONS_Mouse0.75225082
126* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.73405121
127RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.72039662
128P68_20966046_ChIP-Seq_HELA_Human0.70776501
129YY1_22570637_ChIP-Seq_MALME-3M_Human0.69268617
130PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.69098312
131EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.69042157
132TAF2_19829295_ChIP-Seq_ESCs_Human0.67549737
133CREB1_26743006_Chip-Seq_LNCaP_Human0.66593289

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting4.55089480
2MP0005423_abnormal_somatic_nervous4.50911141
3MP0005645_abnormal_hypothalamus_physiol4.27264359
4MP0006276_abnormal_autonomic_nervous3.83927767
5MP0001984_abnormal_olfaction3.81444606
6MP0008995_early_reproductive_senescence3.49615777
7MP0003122_maternal_imprinting3.36141900
8MP0000778_abnormal_nervous_system3.17393465
9MP0010030_abnormal_orbit_morphology3.09714022
10MP0002822_catalepsy3.02100408
11MP0003880_abnormal_central_pattern2.77650631
12MP0008789_abnormal_olfactory_epithelium2.45759378
13MP0002163_abnormal_gland_morphology2.31445059
14MP0002184_abnormal_innervation2.31409812
15MP0005377_hearing/vestibular/ear_phenot2.28393585
16MP0003878_abnormal_ear_physiology2.28393585
17MP0005394_taste/olfaction_phenotype2.19488819
18MP0005499_abnormal_olfactory_system2.19488819
19MP0000566_synostosis2.18477105
20MP0002653_abnormal_ependyma_morphology2.16138247
21MP0006292_abnormal_olfactory_placode2.10040692
22MP0004859_abnormal_synaptic_plasticity2.07003942
23MP0002102_abnormal_ear_morphology2.04314139
24MP0005646_abnormal_pituitary_gland2.00655364
25MP0003121_genomic_imprinting1.96124391
26MP0001529_abnormal_vocalization1.94757763
27MP0002938_white_spotting1.92883174
28MP0001486_abnormal_startle_reflex1.87457924
29MP0000631_abnormal_neuroendocrine_gland1.84932841
30MP0009379_abnormal_foot_pigmentation1.84622204
31MP0002557_abnormal_social/conspecific_i1.69890095
32MP0002063_abnormal_learning/memory/cond1.68978065
33MP0003011_delayed_dark_adaptation1.64694306
34MP0003635_abnormal_synaptic_transmissio1.63740560
35MP0003183_abnormal_peptide_metabolism1.61517489
36MP0002751_abnormal_autonomic_nervous1.60631134
37MP0002638_abnormal_pupillary_reflex1.56838591
38MP0004742_abnormal_vestibular_system1.55235800
39MP0002909_abnormal_adrenal_gland1.55235372
40MP0003942_abnormal_urinary_system1.47526673
41MP0002572_abnormal_emotion/affect_behav1.47059766
42MP0003315_abnormal_perineum_morphology1.45634396
43MP0001502_abnormal_circadian_rhythm1.45172205
44MP0002160_abnormal_reproductive_system1.44462706
45MP0008877_abnormal_DNA_methylation1.44026161
46MP0001188_hyperpigmentation1.41288949
47MP0003646_muscle_fatigue1.39720124
48MP0000538_abnormal_urinary_bladder1.39480474
49MP0004142_abnormal_muscle_tone1.38746286
50MP0001348_abnormal_lacrimal_gland1.37168270
51MP0004133_heterotaxia1.35159374
52MP0003890_abnormal_embryonic-extraembry1.32627640
53MP0005379_endocrine/exocrine_gland_phen1.32366599
54MP0000026_abnormal_inner_ear1.31543383
55MP0000049_abnormal_middle_ear1.30532876
56MP0002928_abnormal_bile_duct1.29095712
57MP0001440_abnormal_grooming_behavior1.26832916
58MP0003861_abnormal_nervous_system1.25574384
59MP0004811_abnormal_neuron_physiology1.25028528
60MP0001346_abnormal_lacrimal_gland1.24476551
61MP0000534_abnormal_ureter_morphology1.24439375
62MP0001986_abnormal_taste_sensitivity1.21319750
63MP0002882_abnormal_neuron_morphology1.20646428
64MP0009745_abnormal_behavioral_response1.20351316
65MP0005551_abnormal_eye_electrophysiolog1.19278802
66MP0003938_abnormal_ear_development1.18061712
67MP0001485_abnormal_pinna_reflex1.16153640
68MP0002734_abnormal_mechanical_nocicepti1.16042880
69MP0002064_seizures1.15923859
70MP0003385_abnormal_body_wall1.15371103
71MP0000955_abnormal_spinal_cord1.14153478
72MP0002733_abnormal_thermal_nociception1.13894946
73MP0000569_abnormal_digit_pigmentation1.13742849
74MP0010386_abnormal_urinary_bladder1.12164935
75MP0002067_abnormal_sensory_capabilities1.11923828
76MP0002152_abnormal_brain_morphology1.11780790
77MP0005409_darkened_coat_color1.10663752
78MP0002735_abnormal_chemical_nociception1.09479460
79MP0002876_abnormal_thyroid_physiology1.08413138
80MP0003787_abnormal_imprinting1.07006532
81MP0009046_muscle_twitch1.06367490
82MP0004270_analgesia1.04826077
83MP0001970_abnormal_pain_threshold1.04539513
84MP0002249_abnormal_larynx_morphology1.04491678
85* MP0002752_abnormal_somatic_nervous1.03799705
86MP0001968_abnormal_touch/_nociception1.03150799
87MP0005257_abnormal_intraocular_pressure1.02695043
88MP0003137_abnormal_impulse_conducting1.02486036
89MP0002272_abnormal_nervous_system1.02457874
90MP0004130_abnormal_muscle_cell1.01957148
91MP0002233_abnormal_nose_morphology1.01071744
92MP0002282_abnormal_trachea_morphology0.99899372
93MP0004885_abnormal_endolymph0.99561745
94MP0000678_abnormal_parathyroid_gland0.98962675
95MP0003879_abnormal_hair_cell0.96946133
96MP0003786_premature_aging0.96219177
97MP0005195_abnormal_posterior_eye0.95430486
98MP0002277_abnormal_respiratory_mucosa0.94347141
99MP0009697_abnormal_copulation0.92955002
100MP0005083_abnormal_biliary_tract0.92544109
101MP0004924_abnormal_behavior0.89075053
102MP0005386_behavior/neurological_phenoty0.89075053
103MP0005187_abnormal_penis_morphology0.88340871
104MP0005084_abnormal_gallbladder_morpholo0.88305905
105MP0001963_abnormal_hearing_physiology0.87851436
106MP0002116_abnormal_craniofacial_bone0.87367272
107MP0002229_neurodegeneration0.86395565
108MP0003119_abnormal_digestive_system0.86365660
109MP0008961_abnormal_basal_metabolism0.85703494
110MP0002069_abnormal_eating/drinking_beha0.84478222
111MP0005389_reproductive_system_phenotype0.84074685
112MP0008004_abnormal_stomach_pH0.81798601
113* MP0002081_perinatal_lethality0.80234830
114MP0002066_abnormal_motor_capabilities/c0.80214849
115MP0005248_abnormal_Harderian_gland0.77439234
116MP0000537_abnormal_urethra_morphology0.75632395
117MP0003948_abnormal_gas_homeostasis0.74484279
118MP0000681_abnormal_thyroid_gland0.74015534
119MP0009250_abnormal_appendicular_skeleto0.73799958
120MP0001542_abnormal_bone_strength0.73042872
121MP0006072_abnormal_retinal_apoptosis0.72459962
122MP0001905_abnormal_dopamine_level0.72118310
123MP0003329_amyloid_beta_deposits0.71193365
124MP0001286_abnormal_eye_development0.71191854
125MP0001919_abnormal_reproductive_system0.70936530
126MP0008260_abnormal_autophagy0.70045770
127MP0001501_abnormal_sleep_pattern0.68798338
128MP0000639_abnormal_adrenal_gland0.66758665
129MP0002736_abnormal_nociception_after0.65492703
130MP0004145_abnormal_muscle_electrophysio0.64878205
131MP0002837_dystrophic_cardiac_calcinosis0.64309512
132MP0009053_abnormal_anal_canal0.63955584
133MP0008775_abnormal_heart_ventricle0.63625597
134MP0001944_abnormal_pancreas_morphology0.62792277
135MP0000516_abnormal_urinary_system0.62623036

Predicted human phenotypes

RankGene SetZ-score
1Abnormal pancreas size (HP:0012094)7.29277514
2Myokymia (HP:0002411)5.72619313
3Failure to thrive in infancy (HP:0001531)4.92452500
4Hepatoblastoma (HP:0002884)4.89924173
5Diastasis recti (HP:0001540)4.73016419
6Neonatal hypoglycemia (HP:0001998)4.50630693
7Neoplasm of the adrenal cortex (HP:0100641)4.37830349
8Polyphagia (HP:0002591)4.35763302
9Metaphyseal dysplasia (HP:0100255)4.14569601
10True hermaphroditism (HP:0010459)4.02306592
11Abnormal eating behavior (HP:0100738)3.78927632
12High anterior hairline (HP:0009890)3.75402346
13Adrenal hypoplasia (HP:0000835)3.68971002
14Supranuclear gaze palsy (HP:0000605)3.67825449
15Abnormal sex determination (HP:0012244)3.49264562
16Sex reversal (HP:0012245)3.49264562
17Agitation (HP:0000713)3.25925993
18Sleep apnea (HP:0010535)3.22549217
19Esotropia (HP:0000565)3.09796550
20Abnormal hair whorl (HP:0010721)3.09240079
21Renal duplication (HP:0000075)3.08862474
22Febrile seizures (HP:0002373)2.93803081
23Hypogonadotrophic hypogonadism (HP:0000044)2.93625561
24Limb dystonia (HP:0002451)2.93192415
25Rib fusion (HP:0000902)2.91221101
26Impaired vibration sensation in the lower limbs (HP:0002166)2.83452851
27Abnormality of the intervertebral disk (HP:0005108)2.80684069
28Optic nerve coloboma (HP:0000588)2.80096238
29Focal motor seizures (HP:0011153)2.79778309
30Elfin facies (HP:0004428)2.76883592
31Deep palmar crease (HP:0006191)2.75284270
32Shawl scrotum (HP:0000049)2.75153521
33Molar tooth sign on MRI (HP:0002419)2.73516607
34Abnormality of midbrain morphology (HP:0002418)2.73516607
35Enlarged kidneys (HP:0000105)2.71169695
36Nephronophthisis (HP:0000090)2.69547634
37Abnormal ciliary motility (HP:0012262)2.68164647
38Exotropia (HP:0000577)2.67059688
39Hypothermia (HP:0002045)2.66711153
40Recurrent corneal erosions (HP:0000495)2.61537383
41Abnormality of the corticospinal tract (HP:0002492)2.60060320
42Renovascular hypertension (HP:0100817)2.59348616
43Morphological abnormality of the middle ear (HP:0008609)2.58276356
44Thoracolumbar scoliosis (HP:0002944)2.57619162
45Focal seizures (HP:0007359)2.56274250
46Bilateral sensorineural hearing impairment (HP:0008619)2.53967416
47Hyperacusis (HP:0010780)2.52805807
48Hyperthyroidism (HP:0000836)2.52103631
49Overgrowth (HP:0001548)2.51780620
50Abnormality of the labia minora (HP:0012880)2.50667284
51Unilateral renal agenesis (HP:0000122)2.47278662
52Pachygyria (HP:0001302)2.45204058
53Drooling (HP:0002307)2.44613048
54Abnormality of macular pigmentation (HP:0008002)2.39975461
55Absent rod-and cone-mediated responses on ERG (HP:0007688)2.39051763
56Absent eyebrow (HP:0002223)2.38875410
57Small hand (HP:0200055)2.38789190
58Midline defect of the nose (HP:0004122)2.37954010
59Double outlet right ventricle (HP:0001719)2.37804227
60Congenital malformation of the right heart (HP:0011723)2.37804227
61Parakeratosis (HP:0001036)2.34893627
62Dynein arm defect of respiratory motile cilia (HP:0012255)2.34513104
63Absent/shortened dynein arms (HP:0200106)2.34513104
64Spastic tetraplegia (HP:0002510)2.33705037
65Atelectasis (HP:0100750)2.31707331
66Abnormality of the renal medulla (HP:0100957)2.28644576
67Gait imbalance (HP:0002141)2.28424045
68Aplasia/Hypoplasia of the lens (HP:0008063)2.28164826
69Thyroid-stimulating hormone excess (HP:0002925)2.25888966
70Nephrogenic diabetes insipidus (HP:0009806)2.25078756
71Hypercalciuria (HP:0002150)2.24445245
72Abnormality of cells of the erythroid lineage (HP:0012130)2.24222343
73Excessive salivation (HP:0003781)2.23725228
74Focal dystonia (HP:0004373)2.22459384
75Progressive sensorineural hearing impairment (HP:0000408)2.22294879
76Renal dysplasia (HP:0000110)2.22128195
77Fetal akinesia sequence (HP:0001989)2.21736113
78Growth hormone deficiency (HP:0000824)2.21488531
79Poor coordination (HP:0002370)2.19429936
80Anomalous pulmonary venous return (HP:0010772)2.17997287
81Abnormal respiratory motile cilium physiology (HP:0012261)2.17369458
82Torticollis (HP:0000473)2.16507582
83Aplasia of the musculature (HP:0100854)2.16355841
84Hip dysplasia (HP:0001385)2.16242250
85Specific learning disability (HP:0001328)2.13756053
86Cortical dysplasia (HP:0002539)2.11553181
87Tubular atrophy (HP:0000092)2.08638404
88Medial flaring of the eyebrow (HP:0010747)2.08157334
89Aplasia/Hypoplasia of the spleen (HP:0010451)2.06976867
90Overriding aorta (HP:0002623)2.06662158
91Lissencephaly (HP:0001339)2.06504558
92Facial shape deformation (HP:0011334)2.06121110
93Potter facies (HP:0002009)2.06121110
94Asplenia (HP:0001746)2.05971882
95Scrotal hypoplasia (HP:0000046)2.03514399
96Narrow nasal bridge (HP:0000446)2.03189048
97Flat cornea (HP:0007720)2.02996768
98Chorioretinal atrophy (HP:0000533)2.01335929
99Spina bifida occulta (HP:0003298)1.99130808
100Abnormal respiratory motile cilium morphology (HP:0005938)1.98232941
101Abnormal respiratory epithelium morphology (HP:0012253)1.98232941
102Congenital primary aphakia (HP:0007707)1.96641794
103Insomnia (HP:0100785)1.96459750
104Wrist flexion contracture (HP:0001239)1.96071852
105Autism (HP:0000717)1.95369458
106Pancreatic fibrosis (HP:0100732)1.95311193
107Cheilitis (HP:0100825)1.94845346
108Urinary bladder sphincter dysfunction (HP:0002839)1.93630173
109Abnormal rod and cone electroretinograms (HP:0008323)1.93555402
110Patellar dislocation (HP:0002999)1.92752901
111Septo-optic dysplasia (HP:0100842)1.92635170
112Trigonocephaly (HP:0000243)1.90737489
113Abnormality of the pulmonary veins (HP:0011718)1.90701030
114Follicular hyperkeratosis (HP:0007502)1.90372759
115Preaxial hand polydactyly (HP:0001177)1.90206092
116Narrow forehead (HP:0000341)1.88003405
117Epiphyseal dysplasia (HP:0002656)1.87790486
118Broad-based gait (HP:0002136)1.87458314
119Primary amenorrhea (HP:0000786)1.86461222
120Anencephaly (HP:0002323)1.85890622
121Visual hallucinations (HP:0002367)1.85560430
122Protruding tongue (HP:0010808)1.83983522
123Labial hypoplasia (HP:0000066)1.83672759
124Aplasia/Hypoplasia of the brainstem (HP:0007362)1.83320880
125Hypoplasia of the brainstem (HP:0002365)1.83320880
126Poor suck (HP:0002033)1.82433937
127Bony spicule pigmentary retinopathy (HP:0007737)1.82248597
128Abnormality of hair growth rate (HP:0011363)1.81995976
129Slow-growing hair (HP:0002217)1.81995976
130Intestinal atresia (HP:0011100)1.81278205
131Neoplasm of the adrenal gland (HP:0100631)1.80810797
132Congenital stationary night blindness (HP:0007642)1.80791084
133Renal hypoplasia (HP:0000089)1.79840225
134Abnormality of the diencephalon (HP:0010662)1.77269630
135Vaginal atresia (HP:0000148)1.76815292
136Hypoventilation (HP:0002791)1.76513310
137Status epilepticus (HP:0002133)1.76405047
138Epileptic encephalopathy (HP:0200134)1.76397594
139Heterochromia iridis (HP:0001100)1.76080262
140Chronic hepatic failure (HP:0100626)1.75477903
141Osteomalacia (HP:0002749)1.75388340
142Occipital encephalocele (HP:0002085)1.75085136
143Horseshoe kidney (HP:0000085)1.74601253
144Bile duct proliferation (HP:0001408)1.74140199
145Abnormal biliary tract physiology (HP:0012439)1.74140199
146Renal Fanconi syndrome (HP:0001994)1.72580817
147Polymicrogyria (HP:0002126)1.72572801
148Megalocornea (HP:0000485)1.72567789
149Anosmia (HP:0000458)1.71943393
150Absent eyelashes (HP:0000561)1.71277814
151Progressive cerebellar ataxia (HP:0002073)1.71141220
152Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.70420755
153Short 4th metacarpal (HP:0010044)1.70420755
154Abolished electroretinogram (ERG) (HP:0000550)1.69972513
155Open mouth (HP:0000194)1.69780157
156Cystic liver disease (HP:0006706)1.69474252
157Male pseudohermaphroditism (HP:0000037)1.69002497
158Craniofacial dystonia (HP:0012179)1.68160568
159Genital tract atresia (HP:0001827)1.67484640
160Hypoplastic female external genitalia (HP:0012815)1.67074595
161Vitreoretinal degeneration (HP:0000655)1.66939878
162Pancreatic cysts (HP:0001737)1.66755136
163Long foot (HP:0001833)1.66348990
164Sclerocornea (HP:0000647)1.64459091
165Abnormality of the lower motor neuron (HP:0002366)1.64288646

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK36.76719537
2SIK23.32536253
3IRAK23.04908492
4MARK12.94025140
5WNK32.91470728
6MAP3K92.81461451
7EPHB22.76199486
8EPHA32.67264541
9ERBB32.58344802
10KSR12.57118610
11WNK42.48097580
12NTRK22.32339285
13DYRK22.14152444
14MAPK132.12874846
15UHMK12.09069933
16BMPR1B2.08960813
17BRD42.00496104
18BCR1.96307665
19TNIK1.83492540
20MAP2K71.82502630
21ERBB21.74100489
22DYRK1B1.72937023
23CASK1.70635285
24PINK11.70397777
25PRPF4B1.59566218
26PAK61.58562459
27IRAK41.49806491
28STK111.48086555
29CAMKK11.46252646
30SRPK11.45571659
31MAP3K41.39959402
32SIK11.39874108
33PRKCH1.39556191
34FGFR21.37078696
35NTRK31.35831815
36ARAF1.35163071
37CDK81.33954080
38DYRK31.27538131
39IRAK11.26493552
40MAP3K111.23492246
41MAP3K121.19486456
42PNCK1.18945721
43ACVR1B1.15584065
44RIPK11.07740201
45PAK31.04759560
46ZAK1.04101861
47CAMKK21.02370973
48MINK11.01413145
49RPS6KA20.99750972
50CDK190.99434574
51SGK30.97419624
52GRK10.96944195
53LIMK10.94812740
54STK160.94779323
55ADRBK20.92082284
56AKT30.89353675
57CSNK1G30.86799989
58SGK2230.86791347
59SGK4940.86791347
60CSNK1E0.85477829
61ICK0.80859773
62EPHA40.80064409
63CDK30.74647846
64TYRO30.72774899
65WNK10.72678096
66DYRK1A0.72517619
67CAMK1G0.71646087
68CSNK1G20.71552886
69MAP2K40.70581706
70MARK20.69780861
71CAMK40.67460363
72CDK180.64353468
73CSNK1A1L0.63252692
74STK390.60941242
75VRK10.60309197
76PIM20.60043642
77PRKACA0.57057108
78CDK50.55775676
79CSNK1G10.54955454
80PRKCI0.54922664
81SGK20.54887289
82MAPK90.54584454
83BMPR20.54168439
84PKN10.53675823
85RPS6KC10.52714341
86RPS6KL10.52714341
87SGK10.50933310
88PRKCZ0.49692433
89TGFBR10.49520199
90MKNK10.49456133
91MAPK80.48493207
92CAMK10.47424970
93AKT10.46673335
94MAP3K60.46340927
95PRKCQ0.45475655
96TAOK10.44644076
97PRKCD0.44531443
98YES10.44466207
99CDK150.44152793
100BRAF0.43005643
101TAOK20.42905865
102STK38L0.42197221
103ATR0.42092191
104MARK30.41707978
105EIF2AK20.41175421
106RPS6KA60.40407274
107DMPK0.39907396
108MAPK40.39875171
109PRKCG0.38936739
110EPHB10.38799819
111ABL20.38692851
112AKT20.38646415
113MKNK20.38490803
114FGFR10.38353885
115NTRK10.38118985
116CDK11A0.37863714
117CSNK1A10.37067016
118PHKG20.36571440
119PHKG10.36571440
120CAMK2B0.36231544
121CAMK1D0.35882256
122INSRR0.34798842
123PRKG10.34462999
124TXK0.33300363
125RPS6KA30.32751739
126BTK0.31943016
127PLK30.31876936
128PAK40.31813179
129MUSK0.31235620
130CDK140.30803353
131TLK10.29789612
132MAPK150.29610602
133ADRBK10.29500419
134PASK0.28830585
135MAP2K20.28331083
136PDGFRA0.28167619
137PRKAA10.27376953
138ROCK10.27309446
139PRKCE0.26711257
140DAPK20.26238304
141FGFR40.26173246
142MAP2K60.25293234
143OXSR10.24842522

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.12351636
2Axon guidance_Homo sapiens_hsa043603.55622265
3Olfactory transduction_Homo sapiens_hsa047403.08436519
4Oxidative phosphorylation_Homo sapiens_hsa001903.02528972
5Parkinsons disease_Homo sapiens_hsa050122.78380011
6Notch signaling pathway_Homo sapiens_hsa043302.46840421
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.22175180
8Morphine addiction_Homo sapiens_hsa050322.13159925
9Synaptic vesicle cycle_Homo sapiens_hsa047212.11387066
10Circadian entrainment_Homo sapiens_hsa047132.09997484
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.08551675
12Ribosome_Homo sapiens_hsa030102.00476810
13GABAergic synapse_Homo sapiens_hsa047271.93651199
14Taste transduction_Homo sapiens_hsa047421.92671638
15Basal cell carcinoma_Homo sapiens_hsa052171.91998960
16Glutamatergic synapse_Homo sapiens_hsa047241.89772674
17Alzheimers disease_Homo sapiens_hsa050101.87264706
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.83704789
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.82553501
20Serotonergic synapse_Homo sapiens_hsa047261.79226085
21Dopaminergic synapse_Homo sapiens_hsa047281.66241652
22Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.55664746
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.54263063
24Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.53795747
25Cocaine addiction_Homo sapiens_hsa050301.51937151
26Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.45872061
27Steroid biosynthesis_Homo sapiens_hsa001001.44116528
28Regulation of autophagy_Homo sapiens_hsa041401.39470382
29Hedgehog signaling pathway_Homo sapiens_hsa043401.39400828
30Cholinergic synapse_Homo sapiens_hsa047251.36799841
31Spliceosome_Homo sapiens_hsa030401.30675236
32mRNA surveillance pathway_Homo sapiens_hsa030151.29363024
33Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.28432323
34Colorectal cancer_Homo sapiens_hsa052101.27787806
35Phototransduction_Homo sapiens_hsa047441.25901671
36Circadian rhythm_Homo sapiens_hsa047101.25427672
37Wnt signaling pathway_Homo sapiens_hsa043101.22070353
38Insulin secretion_Homo sapiens_hsa049111.21782886
39ErbB signaling pathway_Homo sapiens_hsa040121.21500984
40Maturity onset diabetes of the young_Homo sapiens_hsa049501.19449373
41Hippo signaling pathway_Homo sapiens_hsa043901.17299392
42Collecting duct acid secretion_Homo sapiens_hsa049661.15582786
43Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.15180919
44Endometrial cancer_Homo sapiens_hsa052131.13589493
45Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12363509
46Basal transcription factors_Homo sapiens_hsa030221.09823560
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06955217
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.06551648
49VEGF signaling pathway_Homo sapiens_hsa043701.05704541
50Amphetamine addiction_Homo sapiens_hsa050311.03632034
51RNA polymerase_Homo sapiens_hsa030201.03382528
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01110278
53Gap junction_Homo sapiens_hsa045400.98600325
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.95434694
55Alcoholism_Homo sapiens_hsa050340.95421773
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.93851883
57Calcium signaling pathway_Homo sapiens_hsa040200.92805513
58Cardiac muscle contraction_Homo sapiens_hsa042600.91221860
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88418640
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86858735
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.84252877
62Linoleic acid metabolism_Homo sapiens_hsa005910.82873058
63Vibrio cholerae infection_Homo sapiens_hsa051100.81607159
64Sulfur relay system_Homo sapiens_hsa041220.79040406
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.78149809
66Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.78039218
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.76769314
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.76376807
69Oxytocin signaling pathway_Homo sapiens_hsa049210.75855659
70cAMP signaling pathway_Homo sapiens_hsa040240.75254564
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73428257
72Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.72593757
73Melanogenesis_Homo sapiens_hsa049160.72269059
74N-Glycan biosynthesis_Homo sapiens_hsa005100.71956671
75Phagosome_Homo sapiens_hsa041450.71116887
76Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70538128
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70242934
78MicroRNAs in cancer_Homo sapiens_hsa052060.68789930
79Phospholipase D signaling pathway_Homo sapiens_hsa040720.64916980
80Dilated cardiomyopathy_Homo sapiens_hsa054140.64056190
81Melanoma_Homo sapiens_hsa052180.63967455
82Dorso-ventral axis formation_Homo sapiens_hsa043200.63477079
83MAPK signaling pathway_Homo sapiens_hsa040100.63447894
84Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62121929
85Autoimmune thyroid disease_Homo sapiens_hsa053200.62083415
86Ras signaling pathway_Homo sapiens_hsa040140.62077200
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.62050576
88Ether lipid metabolism_Homo sapiens_hsa005650.60593000
89Type II diabetes mellitus_Homo sapiens_hsa049300.59627356
90Long-term depression_Homo sapiens_hsa047300.56190379
91Salivary secretion_Homo sapiens_hsa049700.54540171
92Fanconi anemia pathway_Homo sapiens_hsa034600.54070061
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.53149315
94Thyroid hormone synthesis_Homo sapiens_hsa049180.52104299
95Pathways in cancer_Homo sapiens_hsa052000.50757976
96Gastric acid secretion_Homo sapiens_hsa049710.50110767
97Long-term potentiation_Homo sapiens_hsa047200.49644757
98Renal cell carcinoma_Homo sapiens_hsa052110.49632618
99Huntingtons disease_Homo sapiens_hsa050160.49279556
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48585814
101Chronic myeloid leukemia_Homo sapiens_hsa052200.47396879
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.47210105
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45208427
104Rap1 signaling pathway_Homo sapiens_hsa040150.44917115
105Bile secretion_Homo sapiens_hsa049760.43630844
106GnRH signaling pathway_Homo sapiens_hsa049120.43188032
107Peroxisome_Homo sapiens_hsa041460.40445167
108Inositol phosphate metabolism_Homo sapiens_hsa005620.40352769
109Base excision repair_Homo sapiens_hsa034100.39440703
110cGMP-PKG signaling pathway_Homo sapiens_hsa040220.38793220
111RNA degradation_Homo sapiens_hsa030180.38420958
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.38015917
113Glycerolipid metabolism_Homo sapiens_hsa005610.37739742
114Endocytosis_Homo sapiens_hsa041440.37036179
115Oocyte meiosis_Homo sapiens_hsa041140.35952822
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35704182
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.35520353
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35219496
119Choline metabolism in cancer_Homo sapiens_hsa052310.34219538
120Pancreatic secretion_Homo sapiens_hsa049720.32909764
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32843153
122Lysine degradation_Homo sapiens_hsa003100.32667518
123Ovarian steroidogenesis_Homo sapiens_hsa049130.32630225
124Retinol metabolism_Homo sapiens_hsa008300.32579850
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32062814
126Renin secretion_Homo sapiens_hsa049240.31967164
127Estrogen signaling pathway_Homo sapiens_hsa049150.31729177
128Protein export_Homo sapiens_hsa030600.31569885
129PI3K-Akt signaling pathway_Homo sapiens_hsa041510.31486093
130Prolactin signaling pathway_Homo sapiens_hsa049170.30348528
131Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.29107124
132Fatty acid biosynthesis_Homo sapiens_hsa000610.28830646

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