TXNDC11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exocrine pancreas development (GO:0031017)5.35403907
2signal peptide processing (GO:0006465)4.38282657
3DNA deamination (GO:0045006)4.18311041
4COPI coating of Golgi vesicle (GO:0048205)4.06152543
5Golgi transport vesicle coating (GO:0048200)4.06152543
6intestinal cholesterol absorption (GO:0030299)3.94702338
7maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.92551930
8positive regulation of gamma-delta T cell activation (GO:0046645)3.78040231
9regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.69393329
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.47396302
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.47396302
12protein retention in ER lumen (GO:0006621)3.44925411
13UDP-N-acetylglucosamine metabolic process (GO:0006047)3.31585813
14antigen processing and presentation of endogenous antigen (GO:0019883)3.26463759
15negative regulation of erythrocyte differentiation (GO:0045647)3.22118043
16T cell migration (GO:0072678)3.16836452
17positive regulation of B cell differentiation (GO:0045579)3.03448066
18immunoglobulin mediated immune response (GO:0016064)3.02695711
19activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.02260561
20myeloid dendritic cell differentiation (GO:0043011)3.01348689
21positive regulation of nuclease activity (GO:0032075)2.98350510
22COPII vesicle coating (GO:0048208)2.97466977
23endoplasmic reticulum unfolded protein response (GO:0030968)2.96451836
24negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.95189804
25negative regulation of cell killing (GO:0031342)2.95189804
26detection of other organism (GO:0098543)2.91112856
27detection of bacterium (GO:0016045)2.90678678
28cellular response to unfolded protein (GO:0034620)2.90114050
29response to muramyl dipeptide (GO:0032495)2.89484495
30regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.89174397
31deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.88161304
32neutrophil mediated immunity (GO:0002446)2.86432515
33positive regulation by symbiont of host defense response (GO:0052509)2.86268862
34modulation by symbiont of host defense response (GO:0052031)2.86268862
35modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.86268862
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.86268862
37positive regulation by organism of defense response of other organism involved in symbiotic interact2.86268862
38modulation by symbiont of host immune response (GO:0052553)2.86268862
39protein N-linked glycosylation via asparagine (GO:0018279)2.86117195
40cellular response to type I interferon (GO:0071357)2.86050688
41type I interferon signaling pathway (GO:0060337)2.86050688
42B cell receptor signaling pathway (GO:0050853)2.85554199
43regulation of nuclease activity (GO:0032069)2.85274569
44negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.84724741
45response to type I interferon (GO:0034340)2.84697831
46complement activation, classical pathway (GO:0006958)2.84499872
47ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.84361467
48regulation of gamma-delta T cell differentiation (GO:0045586)2.83863359
49regulation of cholesterol homeostasis (GO:2000188)2.81867675
50positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.81674319
51peptidyl-asparagine modification (GO:0018196)2.80579833
52tRNA methylation (GO:0030488)2.79692843
53natural killer cell activation involved in immune response (GO:0002323)2.75297293
54proline biosynthetic process (GO:0006561)2.75075098
55lipopolysaccharide-mediated signaling pathway (GO:0031663)2.74540628
56pinocytosis (GO:0006907)2.73785550
57cellular response to topologically incorrect protein (GO:0035967)2.73093230
58macrophage activation involved in immune response (GO:0002281)2.72989619
59glycolipid catabolic process (GO:0019377)2.72050433
60regulation of gamma-delta T cell activation (GO:0046643)2.71759926
61nucleoside diphosphate catabolic process (GO:0009134)2.68174599
62mitochondrial DNA replication (GO:0006264)2.67421454
63digestion (GO:0007586)2.66765247
64myeloid dendritic cell activation (GO:0001773)2.65366384
65ceramide catabolic process (GO:0046514)2.64334101
66glycosphingolipid catabolic process (GO:0046479)2.62839952
67peptide catabolic process (GO:0043171)2.61926820
68response to peptidoglycan (GO:0032494)2.61441721
69ER-nucleus signaling pathway (GO:0006984)2.61387197
70NIK/NF-kappaB signaling (GO:0038061)2.61177919
71regulation of B cell differentiation (GO:0045577)2.60862080
72protein N-linked glycosylation (GO:0006487)2.60465901
73interferon-gamma-mediated signaling pathway (GO:0060333)2.59921167
74telomere maintenance via semi-conservative replication (GO:0032201)2.58860587
75proline metabolic process (GO:0006560)2.57362024
76GDP-mannose metabolic process (GO:0019673)2.56208422
77germinal center formation (GO:0002467)2.55326955
78defense response to protozoan (GO:0042832)2.54674510
79B cell homeostasis (GO:0001782)2.54531875
80T-helper 1 type immune response (GO:0042088)2.54058837
81negative regulation of interleukin-12 production (GO:0032695)2.52267793
82regulation of dendritic cell antigen processing and presentation (GO:0002604)2.51743931
83amino sugar catabolic process (GO:0046348)2.51604146
84cellular extravasation (GO:0045123)2.51346208
85detection of external biotic stimulus (GO:0098581)2.49996638
86valine metabolic process (GO:0006573)2.47767378
87rRNA modification (GO:0000154)2.47625097
88regulation of type I interferon-mediated signaling pathway (GO:0060338)2.47354466
89regulation of nuclear cell cycle DNA replication (GO:0033262)2.44144866
90RNA destabilization (GO:0050779)2.43897695
91regulation of vitamin metabolic process (GO:0030656)2.43839380
92* response to endoplasmic reticulum stress (GO:0034976)2.43094802
93deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.42514752
94protein maturation by protein folding (GO:0022417)2.42073696
95embryonic process involved in female pregnancy (GO:0060136)2.42061970
96response to protozoan (GO:0001562)2.41208642
97neutrophil activation (GO:0042119)2.40981543
98mannose metabolic process (GO:0006013)2.40620668
99regulation of B cell receptor signaling pathway (GO:0050855)2.39922419
100mature B cell differentiation (GO:0002335)2.39777512
101folic acid-containing compound biosynthetic process (GO:0009396)2.39630103
102regulation of necroptotic process (GO:0060544)2.39530939
103positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.38886714
104negative regulation of myeloid cell apoptotic process (GO:0033033)2.37436197
105positive thymic T cell selection (GO:0045059)2.36929158
106CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.36251540
107protein activation cascade (GO:0072376)2.35922026
108response to laminar fluid shear stress (GO:0034616)2.34134764
109RNA methylation (GO:0001510)2.34117670
110respiratory burst (GO:0045730)2.33604293
111positive regulation of interferon-alpha production (GO:0032727)2.31857029
112regulation of vitamin D biosynthetic process (GO:0060556)2.30093310
113regulation of T cell tolerance induction (GO:0002664)2.29732880
114detection of molecule of bacterial origin (GO:0032490)2.29407605
115low-density lipoprotein particle clearance (GO:0034383)2.29282364
116negative regulation of fibrinolysis (GO:0051918)2.28963436
117plasma lipoprotein particle assembly (GO:0034377)2.28290804
118protein-lipid complex assembly (GO:0065005)2.28051623
119oligosaccharide catabolic process (GO:0009313)2.27488602
120dendritic cell chemotaxis (GO:0002407)2.27437946
121sequestering of metal ion (GO:0051238)2.26545983
122regulation of cholesterol storage (GO:0010885)2.26101017
123folic acid metabolic process (GO:0046655)2.25988297
124rRNA methylation (GO:0031167)2.25960966
125apoptotic cell clearance (GO:0043277)2.25867887
126regulation of necrotic cell death (GO:0010939)2.25541218
127deoxyribonucleotide biosynthetic process (GO:0009263)2.25335267
128pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.24374646
129regulation of interferon-alpha production (GO:0032647)2.24091597
130myeloid leukocyte mediated immunity (GO:0002444)2.23776641
131superoxide anion generation (GO:0042554)2.23479445
132phospholipid efflux (GO:0033700)2.23213604
133modulation by symbiont of host cellular process (GO:0044068)2.23186168
134positive regulation of extracellular matrix organization (GO:1903055)2.23152276
135neutrophil activation involved in immune response (GO:0002283)2.22893444
136antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.22703370
137lymphocyte migration (GO:0072676)2.22257597
138telomere maintenance via recombination (GO:0000722)2.22206830
139negative regulation of cytokine production involved in immune response (GO:0002719)2.21535601
140DNA synthesis involved in DNA repair (GO:0000731)2.21195797
141complement activation (GO:0006956)2.20427410
142protein carboxylation (GO:0018214)2.20353464
143peptidyl-glutamic acid carboxylation (GO:0017187)2.20353464
144negative regulation of phagocytosis (GO:0050765)2.20296097
145negative regulation of granulocyte differentiation (GO:0030853)2.20117596
146endocrine pancreas development (GO:0031018)2.20046942
147mRNA modification (GO:0016556)2.19754719
148amyloid precursor protein catabolic process (GO:0042987)2.19664106
149dendritic cell differentiation (GO:0097028)2.19573151
150DNA strand elongation involved in DNA replication (GO:0006271)2.19274418
151response to thyroid hormone (GO:0097066)2.19254050
152antigen processing and presentation via MHC class Ib (GO:0002475)2.19049786
153regulation of antigen processing and presentation (GO:0002577)2.18798914
154DNA strand elongation (GO:0022616)2.18685594
155regulation of cholesterol esterification (GO:0010872)2.18581511
156mitochondrial calcium ion transport (GO:0006851)2.17755293
157positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.17653192
158negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.17353290
159regulation of leukocyte degranulation (GO:0043300)2.16951143
160regulation of B cell apoptotic process (GO:0002902)2.16803916
161glycine metabolic process (GO:0006544)2.16483553
162nucleotide-sugar metabolic process (GO:0009225)2.16472673
163regulation of tolerance induction (GO:0002643)2.16315003
164regulation of interferon-beta biosynthetic process (GO:0045357)2.16130334
165negative regulation of toll-like receptor signaling pathway (GO:0034122)2.15781456
166mature B cell differentiation involved in immune response (GO:0002313)2.15620099
167tetrahydrofolate metabolic process (GO:0046653)2.15224988
168ribosomal small subunit assembly (GO:0000028)2.14750515
169N-acetylneuraminate metabolic process (GO:0006054)2.14684571
170regulation of B cell proliferation (GO:0030888)2.14385892
171membrane lipid catabolic process (GO:0046466)2.13600642
172folic acid-containing compound metabolic process (GO:0006760)2.12197173
173regulation of superoxide anion generation (GO:0032928)2.11844437
174intestinal absorption (GO:0050892)2.11751454
175positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.10892588

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.66256984
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.19706475
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.99108328
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.13147134
5BP1_19119308_ChIP-ChIP_Hs578T_Human2.88663954
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.83207723
7NOTCH1_21737748_ChIP-Seq_TLL_Human2.62202153
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.51389144
9GATA1_22025678_ChIP-Seq_K562_Human2.50939314
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.40464373
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.40402904
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.39989125
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.38724492
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.36016042
15RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.29745565
16MYC_22102868_ChIP-Seq_BL_Human2.26186969
17FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.18730888
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.14540092
19EGR1_23403033_ChIP-Seq_LIVER_Mouse2.14281167
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.06927078
21JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.04747271
22SFPI1_20887958_ChIP-Seq_HPC-7_Mouse2.02140689
23LXR_22292898_ChIP-Seq_THP-1_Human2.01897230
24ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.00401712
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.00014692
26GABP_17652178_ChIP-ChIP_JURKAT_Human1.97253396
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.96003726
28* TCF7_22412390_ChIP-Seq_EML_Mouse1.95917093
29* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.95862469
30TP63_17297297_ChIP-ChIP_HaCaT_Human1.94372176
31MYC_18555785_ChIP-Seq_MESCs_Mouse1.92125813
32CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.89609728
33VDR_21846776_ChIP-Seq_THP-1_Human1.89543951
34KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.88876092
35CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.88426102
36* SPI1_23547873_ChIP-Seq_NB4_Human1.87628513
37CIITA_25753668_ChIP-Seq_RAJI_Human1.86972107
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.83721843
39SCL_19346495_ChIP-Seq_HPC-7_Human1.81362379
40FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.81318706
41VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.81209042
42EGR1_19374776_ChIP-ChIP_THP-1_Human1.80414066
43MYB_26560356_Chip-Seq_TH1_Human1.79658673
44* VDR_23849224_ChIP-Seq_CD4+_Human1.79115494
45PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.75232300
46E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.74968138
47RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.73853588
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.72768502
49IRF8_27001747_Chip-Seq_BMDM_Mouse1.72317741
50FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.72168747
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.72027095
52SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.69866569
53MYB_26560356_Chip-Seq_TH2_Human1.68895319
54EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.67778650
55SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.65412609
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62191140
57ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.61751239
58FOXP3_21729870_ChIP-Seq_TREG_Human1.60552821
59MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.58555513
60EST1_17652178_ChIP-ChIP_JURKAT_Human1.57845647
61TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.56991656
62STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.56680928
63FOXM1_23109430_ChIP-Seq_U2OS_Human1.56354767
64MYB_21317192_ChIP-Seq_ERMYB_Mouse1.55678058
65MYC_19030024_ChIP-ChIP_MESCs_Mouse1.54445666
66NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.53256462
67MYC_18358816_ChIP-ChIP_MESCs_Mouse1.53010791
68SPI1_23127762_ChIP-Seq_K562_Human1.52752207
69KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.52275362
70* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.51417752
71RACK7_27058665_Chip-Seq_MCF-7_Human1.50927051
72KDM2B_26808549_Chip-Seq_DND41_Human1.50555722
73BRD4_27068464_Chip-Seq_AML-cells_Mouse1.49788566
74ETS1_20019798_ChIP-Seq_JURKAT_Human1.48298365
75FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.47687045
76GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.46930848
77E2F1_21310950_ChIP-Seq_MCF-7_Human1.46033136
78STAT4_19710469_ChIP-ChIP_TH1__Mouse1.43702505
79* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42281354
80* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.42083968
81PPARA_22158963_ChIP-Seq_LIVER_Mouse1.41751397
82CLOCK_20551151_ChIP-Seq_293T_Human1.41408793
83* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.41307743
84* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.40822447
85ESR2_21235772_ChIP-Seq_MCF-7_Human1.39942634
86TP63_19390658_ChIP-ChIP_HaCaT_Human1.38631643
87GATA1_19941826_ChIP-Seq_K562_Human1.37990526
88* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.37902400
89* RXR_22158963_ChIP-Seq_LIVER_Mouse1.36118913
90RUNX_20019798_ChIP-Seq_JUKART_Human1.35982322
91* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35537406
92MAF_26560356_Chip-Seq_TH1_Human1.33613714
93RUNX1_22412390_ChIP-Seq_EML_Mouse1.32477244
94GATA1_19941827_ChIP-Seq_MEL_Mouse1.31331507
95STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.31286933
96FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.31040588
97ELK1_19687146_ChIP-ChIP_HELA_Human1.30307471
98PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29896713
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.29332284
100UTX_26944678_Chip-Seq_JUKART_Human1.29242402
101TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27606489
102STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26374430
103IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.25623794
104SRF_21415370_ChIP-Seq_HL-1_Mouse1.25495327
105SOX2_27498859_Chip-Seq_STOMACH_Mouse1.22569448
106LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.20556247
107VDR_24763502_ChIP-Seq_THP-1_Human1.20129489
108* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.20017641
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.18891463
110KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.17949420
111* GABP_19822575_ChIP-Seq_HepG2_Human1.17012622
112GATA2_21666600_ChIP-Seq_HMVEC_Human1.16854642
113NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16679047
114CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16228905
115NELFA_20434984_ChIP-Seq_ESCs_Mouse1.15884688
116DCP1A_22483619_ChIP-Seq_HELA_Human1.14973306
117MYC_19079543_ChIP-ChIP_MESCs_Mouse1.14534455
118* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13681851
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.12493791
120GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.12235369
121* NCOR1_26117541_ChIP-Seq_K562_Human1.09793601
122PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09086943
123KDM5A_27292631_Chip-Seq_BREAST_Human1.07393593
124* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.07350188
125VDR_24787735_ChIP-Seq_THP-1_Human1.06572793
126TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.05900357
127CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05505721
128STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04630903
129* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.04516760
130ELF1_20517297_ChIP-Seq_JURKAT_Human1.03548878
131TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02480012
132BCOR_27268052_Chip-Seq_Bcells_Human1.02366382
133PU_27001747_Chip-Seq_BMDM_Mouse1.01838688
134GATA3_27048872_Chip-Seq_THYMUS_Human1.01706934
135ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.00787207
136KDM2B_26808549_Chip-Seq_JURKAT_Human1.00580280
137PU.1_20513432_ChIP-Seq_Bcells_Mouse1.00069091
138CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99847985
139E2F1_18555785_ChIP-Seq_MESCs_Mouse0.99314059
140HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.98428987
141YY1_21170310_ChIP-Seq_MESCs_Mouse0.97874302
142MAF_26560356_Chip-Seq_TH2_Human0.97844680
143NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97280255
144* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97166920
145NANOG_18555785_ChIP-Seq_MESCs_Mouse0.96426290
146ZNF263_19887448_ChIP-Seq_K562_Human0.96397126
147KDM2B_26808549_Chip-Seq_K562_Human0.96196546
148* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.95897782
149BCL6_27268052_Chip-Seq_Bcells_Human0.95333917
150HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.91855552
151LXR_22158963_ChIP-Seq_LIVER_Mouse0.91558797
152SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89118560

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.04328255
2MP0001835_abnormal_antigen_presentation2.94712109
3MP0005058_abnormal_lysosome_morphology2.88914056
4MP0005365_abnormal_bile_salt2.82153190
5MP0005220_abnormal_exocrine_pancreas2.76789535
6MP0001666_abnormal_nutrient_absorption2.75720620
7MP0005451_abnormal_body_composition2.51434952
8MP0001800_abnormal_humoral_immune2.44993124
9MP0005387_immune_system_phenotype2.10838149
10MP0001790_abnormal_immune_system2.10838149
11MP0004264_abnormal_extraembryonic_tissu2.08616909
12MP0005083_abnormal_biliary_tract2.07721824
13MP0002452_abnormal_antigen_presenting2.06716740
14MP0003172_abnormal_lysosome_physiology2.05597977
15MP0003436_decreased_susceptibility_to1.97777245
16MP0002693_abnormal_pancreas_physiology1.97456600
17MP0005671_abnormal_response_to1.97102704
18MP0002396_abnormal_hematopoietic_system1.97086775
19MP0003763_abnormal_thymus_physiology1.95838125
20MP0002723_abnormal_immune_serum1.91124614
21MP0005000_abnormal_immune_tolerance1.82771163
22MP0002139_abnormal_hepatobiliary_system1.82217184
23MP0002420_abnormal_adaptive_immunity1.81860800
24MP0003868_abnormal_feces_composition1.81057099
25MP0000490_abnormal_crypts_of1.81014514
26MP0001819_abnormal_immune_cell1.79262076
27MP0001873_stomach_inflammation1.77708425
28MP0002398_abnormal_bone_marrow1.75562016
29MP0002419_abnormal_innate_immunity1.74553822
30MP0000685_abnormal_immune_system1.69590005
31MP0000689_abnormal_spleen_morphology1.67814927
32MP0009785_altered_susceptibility_to1.64777263
33MP0005025_abnormal_response_to1.64036784
34MP0009333_abnormal_splenocyte_physiolog1.63656923
35MP0008058_abnormal_DNA_repair1.62949225
36MP0000716_abnormal_immune_system1.62571071
37MP0001853_heart_inflammation1.62208627
38MP0005085_abnormal_gallbladder_physiolo1.58059988
39MP0006082_CNS_inflammation1.56386964
40MP0001845_abnormal_inflammatory_respons1.56092017
41MP0001944_abnormal_pancreas_morphology1.50472191
42MP0003111_abnormal_nucleus_morphology1.49523370
43MP0002722_abnormal_immune_system1.49440882
44MP0010155_abnormal_intestine_physiology1.48479586
45MP0002138_abnormal_hepatobiliary_system1.47271737
46MP0003252_abnormal_bile_duct1.47045812
47MP0010094_abnormal_chromosome_stability1.46812140
48MP0002429_abnormal_blood_cell1.42987721
49MP0002166_altered_tumor_susceptibility1.42727190
50MP0002405_respiratory_system_inflammati1.40547407
51MP0005084_abnormal_gallbladder_morpholo1.40453972
52MP0005464_abnormal_platelet_physiology1.39834027
53MP0004808_abnormal_hematopoietic_stem1.37307751
54MP0002148_abnormal_hypersensitivity_rea1.37156294
55MP0006054_spinal_hemorrhage1.36192178
56MP0000703_abnormal_thymus_morphology1.34908664
57MP0002998_abnormal_bone_remodeling1.34858121
58MP0008260_abnormal_autophagy1.34854995
59MP0003724_increased_susceptibility_to1.34222366
60MP0000604_amyloidosis1.31277947
61MP0005360_urolithiasis1.28428880
62MP0010234_abnormal_vibrissa_follicle1.26795859
63MP0005174_abnormal_tail_pigmentation1.25647620
64MP0003303_peritoneal_inflammation1.24999600
65MP0002006_tumorigenesis1.23957575
66MP0003075_altered_response_to1.22541922
67MP0008469_abnormal_protein_level1.21085439
68MP0004510_myositis1.20706972
69MP0009643_abnormal_urine_homeostasis1.17783573
70MP0009840_abnormal_foam_cell1.16221565
71MP0005076_abnormal_cell_differentiation1.16166993
72MP0008004_abnormal_stomach_pH1.15951795
73MP0008057_abnormal_DNA_replication1.15707946
74MP0000371_diluted_coat_color1.15682809
75MP0003300_gastrointestinal_ulcer1.14662167
76MP0003453_abnormal_keratinocyte_physiol1.14620070
77MP0003077_abnormal_cell_cycle1.14338405
78MP0005670_abnormal_white_adipose1.14037921
79MP0003195_calcinosis1.13572465
80MP0005075_abnormal_melanosome_morpholog1.13566130
81MP0003091_abnormal_cell_migration1.13543672
82MP0003656_abnormal_erythrocyte_physiolo1.13359353
83MP0009278_abnormal_bone_marrow1.12081739
84MP0009764_decreased_sensitivity_to1.11555932
85MP0000465_gastrointestinal_hemorrhage1.10580949
86MP0002277_abnormal_respiratory_mucosa1.10031698
87MP0002876_abnormal_thyroid_physiology1.09927093
88MP0002019_abnormal_tumor_incidence1.07391904
89MP0000566_synostosis1.06296449
90MP0005166_decreased_susceptibility_to1.06095874
91MP0001986_abnormal_taste_sensitivity1.04091515
92MP0002132_abnormal_respiratory_system1.03937815
93MP0006292_abnormal_olfactory_placode1.03178332
94MP0000609_abnormal_liver_physiology1.02601793
95MP0000858_altered_metastatic_potential1.00876531
96MP0000613_abnormal_salivary_gland0.99988608
97MP0000015_abnormal_ear_pigmentation0.99314355
98MP0003191_abnormal_cellular_cholesterol0.98851516
99MP0001545_abnormal_hematopoietic_system0.97370121
100MP0005397_hematopoietic_system_phenotyp0.97370121
101MP0005310_abnormal_salivary_gland0.95544410
102MP0003828_pulmonary_edema0.93783332
103MP0003866_abnormal_defecation0.93494784
104MP0002933_joint_inflammation0.92817958
105MP0003186_abnormal_redox_activity0.91056868
106MP0004782_abnormal_surfactant_physiolog0.90432798
107MP0005164_abnormal_response_to0.89177995
108MP0008438_abnormal_cutaneous_collagen0.88665355
109MP0001764_abnormal_homeostasis0.88462238
110MP0003183_abnormal_peptide_metabolism0.88251651
111MP0003566_abnormal_cell_adhesion0.87884773
112MP0004947_skin_inflammation0.87601539
113MP0008007_abnormal_cellular_replicative0.87600819
114MP0000343_altered_response_to0.87314836
115MP0005023_abnormal_wound_healing0.86728775
116MP0002136_abnormal_kidney_physiology0.86061209
117MP0004381_abnormal_hair_follicle0.85173342
118MP0001919_abnormal_reproductive_system0.83759764
119MP0001663_abnormal_digestive_system0.83706393
120MP0001851_eye_inflammation0.82650177
121MP0002877_abnormal_melanocyte_morpholog0.82377175
122MP0004957_abnormal_blastocyst_morpholog0.82196818
123MP0005332_abnormal_amino_acid0.81409214
124MP0001533_abnormal_skeleton_physiology0.81283786
125MP0000598_abnormal_liver_morphology0.80577374
126MP0010329_abnormal_lipoprotein_level0.80290132
127MP0002928_abnormal_bile_duct0.79169547
128MP0003329_amyloid_beta_deposits0.78469571
129MP0009763_increased_sensitivity_to0.77869332
130MP0001186_pigmentation_phenotype0.77783587
131MP0002118_abnormal_lipid_homeostasis0.77736353
132MP0000249_abnormal_blood_vessel0.76945239
133MP0003045_fibrosis0.76467135
134MP0003448_altered_tumor_morphology0.75101012
135MP0005389_reproductive_system_phenotype0.74939162
136MP0005319_abnormal_enzyme/_coenzyme0.74214731
137MP0003705_abnormal_hypodermis_morpholog0.73975665
138MP0003806_abnormal_nucleotide_metabolis0.73759242

Predicted human phenotypes

RankGene SetZ-score
1B lymphocytopenia (HP:0010976)4.70572602
2Abnormality of B cell number (HP:0010975)4.70572602
3Agammaglobulinemia (HP:0004432)4.25125448
4Systemic lupus erythematosus (HP:0002725)3.73338713
5Recurrent viral infections (HP:0004429)3.70221820
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.61022711
7IgM deficiency (HP:0002850)3.56484433
8Colitis (HP:0002583)3.54432380
9Reduced antithrombin III activity (HP:0001976)3.43378629
10Dysostosis multiplex (HP:0000943)3.42504317
11Abnormality of glycolipid metabolism (HP:0010969)3.41837861
12Abnormality of liposaccharide metabolism (HP:0010968)3.41837861
13Abnormality of glycosphingolipid metabolism (HP:0004343)3.41837861
14Chromsome breakage (HP:0040012)3.28989937
15Abnormal delayed hypersensitivity skin test (HP:0002963)3.27676746
16Meningitis (HP:0001287)3.22563025
17Inflammation of the large intestine (HP:0002037)3.20017057
18Deep venous thrombosis (HP:0002625)3.18077451
19Type I transferrin isoform profile (HP:0003642)3.13307799
20Gastrointestinal inflammation (HP:0004386)3.12602937
21Vacuolated lymphocytes (HP:0001922)3.00443593
22Granulocytopenia (HP:0001913)2.90191932
23Abnormality of T cell physiology (HP:0011840)2.87965793
24Panhypogammaglobulinemia (HP:0003139)2.87574380
25Abnormal protein glycosylation (HP:0012346)2.84674153
26Abnormal glycosylation (HP:0012345)2.84674153
27Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.84674153
28Abnormal protein N-linked glycosylation (HP:0012347)2.84674153
29Complement deficiency (HP:0004431)2.84637587
30Gastrointestinal stroma tumor (HP:0100723)2.81326720
31Vasculitis (HP:0002633)2.77423137
32Glomerulonephritis (HP:0000099)2.75616724
33Recurrent sinusitis (HP:0011108)2.75196913
34Cellulitis (HP:0100658)2.74732464
35Recurrent fungal infections (HP:0002841)2.74381271
36Abnormality of pyrimidine metabolism (HP:0004353)2.72887230
37Abnormality of complement system (HP:0005339)2.71671774
38Recurrent abscess formation (HP:0002722)2.67538114
39Thyroiditis (HP:0100646)2.64763232
40Recurrent bronchitis (HP:0002837)2.62851152
41Purpura (HP:0000979)2.62038830
42Chronic obstructive pulmonary disease (HP:0006510)2.60003091
43Obstructive lung disease (HP:0006536)2.60003091
44Malnutrition (HP:0004395)2.57149386
45Loss of speech (HP:0002371)2.53738759
46Recurrent pneumonia (HP:0006532)2.53558791
47Increased cerebral lipofuscin (HP:0011813)2.51955897
48Recurrent bacterial skin infections (HP:0005406)2.50572739
49Myositis (HP:0100614)2.49954682
50Abnormality of the common coagulation pathway (HP:0010990)2.48412283
51Reticulocytopenia (HP:0001896)2.47514840
52Abnormality of the intrinsic pathway (HP:0010989)2.45390265
53Hemorrhage of the eye (HP:0011885)2.44209063
54Abnormality of T cells (HP:0002843)2.43206156
55Orchitis (HP:0100796)2.41792549
56Abnormality of monocarboxylic acid metabolism (HP:0010996)2.41532323
57Severe combined immunodeficiency (HP:0004430)2.39582383
58Mediastinal lymphadenopathy (HP:0100721)2.39065351
59Gastrointestinal infarctions (HP:0005244)2.38085359
60Gingival bleeding (HP:0000225)2.37034079
61Nuclear cataract (HP:0100018)2.36350770
62Hypoglycemic coma (HP:0001325)2.35495705
63Eczematoid dermatitis (HP:0000976)2.35265935
64Hypoproteinemia (HP:0003075)2.32244285
65Duplicated collecting system (HP:0000081)2.31945850
66Recurrent cutaneous fungal infections (HP:0011370)2.31149792
67Chronic mucocutaneous candidiasis (HP:0002728)2.31149792
68Hypoglycemic seizures (HP:0002173)2.30000706
69Flat acetabular roof (HP:0003180)2.27537405
70Asymmetric septal hypertrophy (HP:0001670)2.26840850
71Hyperactive renin-angiotensin system (HP:0000841)2.25614535
72Osteomyelitis (HP:0002754)2.25562488
73Emphysema (HP:0002097)2.25324220
74Abnormality of the fingertips (HP:0001211)2.24848179
75Interstitial pulmonary disease (HP:0006530)2.23642636
76Recurrent lower respiratory tract infections (HP:0002783)2.23117475
77Spontaneous hematomas (HP:0007420)2.22657571
78Increased serum ferritin (HP:0003281)2.21958295
79Eosinophilia (HP:0001880)2.21660991
80Elevated erythrocyte sedimentation rate (HP:0003565)2.21038833
81Abnormality of chromosome stability (HP:0003220)2.18939661
82Increased neuronal autofluorescent lipopigment (HP:0002074)2.17502755
83Xanthomatosis (HP:0000991)2.17251067
84IgA deficiency (HP:0002720)2.16927620
85Proximal tubulopathy (HP:0000114)2.16075614
86Nephritis (HP:0000123)2.15838625
87Vertebral compression fractures (HP:0002953)2.13827528
88Clubbing of toes (HP:0100760)2.13181407
89Chronic diarrhea (HP:0002028)2.13105486
90Urticaria (HP:0001025)2.12049072
91Pustule (HP:0200039)2.11914489
92Increased IgE level (HP:0003212)2.11804434
93Optic neuritis (HP:0100653)2.11591480
94Retrobulbar optic neuritis (HP:0100654)2.11591480
95Epistaxis (HP:0000421)2.11454892
96Abnormality of the renal collecting system (HP:0004742)2.09573844
97Recurrent gram-negative bacterial infections (HP:0005420)2.08322320
98Hypertensive crisis (HP:0100735)2.08254576
99Acute lymphatic leukemia (HP:0006721)2.08128602
100IgG deficiency (HP:0004315)2.07627344
101Autoimmune thrombocytopenia (HP:0001973)2.07387264
102Neutropenia (HP:0001875)2.06025727
103T lymphocytopenia (HP:0005403)2.05561723
104Abnormality of polysaccharide metabolism (HP:0011012)2.05288495
105Abnormality of glycosaminoglycan metabolism (HP:0004371)2.05288495
106Abnormality of mucopolysaccharide metabolism (HP:0011020)2.05288495
107Abnormality of macrophages (HP:0004311)2.04183972
108Leukopenia (HP:0001882)2.03513719
109Combined immunodeficiency (HP:0005387)2.03026867
110Verrucae (HP:0200043)2.02525421
111Papilloma (HP:0012740)2.02525421
112Amyloidosis (HP:0011034)2.02348144
113Thrombocytosis (HP:0001894)2.00497191
114Recurrent skin infections (HP:0001581)1.99087990
115Restrictive lung disease (HP:0002091)1.98906903
116Joint hemorrhage (HP:0005261)1.98884326
117Bone marrow hypocellularity (HP:0005528)1.98788071
118Premature loss of primary teeth (HP:0006323)1.98321223
119Mucopolysacchariduria (HP:0008155)1.97647938
120Urinary glycosaminoglycan excretion (HP:0003541)1.97647938
121Symptomatic seizures (HP:0011145)1.97453507
122Conjugated hyperbilirubinemia (HP:0002908)1.97428938
123Lymphopenia (HP:0001888)1.97340512
124Autoimmune hemolytic anemia (HP:0001890)1.97018485
125Aplasia/Hypoplasia of the uvula (HP:0010293)1.95839242
126Hypoplasia of the thymus (HP:0000778)1.94795382
127Abnormality of the preputium (HP:0100587)1.93998083
128Hyperinsulinemic hypoglycemia (HP:0000825)1.93590199
129Lymphoma (HP:0002665)1.92687700
130Chronic otitis media (HP:0000389)1.90838572
131Sepsis (HP:0100806)1.89861246
132Hypophosphatemia (HP:0002148)1.89779105
133Abnormality of T cell number (HP:0011839)1.89411236
134Seborrheic dermatitis (HP:0001051)1.89298111
135Abnormality of endocrine pancreas physiology (HP:0012093)1.88417789
136Abnormality of the pancreatic islet cells (HP:0006476)1.88417789
137Fatigue (HP:0012378)1.88026420
138Meckel diverticulum (HP:0002245)1.87933443
139Prolonged partial thromboplastin time (HP:0003645)1.87742571
140Abnormality of eosinophils (HP:0001879)1.86662273
141Ovoid vertebral bodies (HP:0003300)1.85785766
142Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.85426931
143Thin bony cortex (HP:0002753)1.85130381
144Petechiae (HP:0000967)1.84433314
145Abnormality of cells of the lymphoid lineage (HP:0012140)1.83591329
146Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.82566865
147Periodontitis (HP:0000704)1.82428224
148Abnormality of iron homeostasis (HP:0011031)1.81451864
149Bronchitis (HP:0012387)1.79932994
150Thoracic kyphosis (HP:0002942)1.79806422
151Gingivitis (HP:0000230)1.79063708
152Generalized aminoaciduria (HP:0002909)1.77205910
153Pulmonary infiltrates (HP:0002113)1.76912280
154Aplastic anemia (HP:0001915)1.75407237
155Abnormality of the ileum (HP:0001549)1.74541149
156Hypergammaglobulinemia (HP:0010702)1.73972764
157Prolonged bleeding time (HP:0003010)1.73751072
158Decreased circulating renin level (HP:0003351)1.73686311
159Encephalitis (HP:0002383)1.73038413
160Renal cortical cysts (HP:0000803)1.72776548
161Cheilitis (HP:0100825)1.72340869
162Hemoptysis (HP:0002105)1.71753784
163Myocardial infarction (HP:0001658)1.71636275
164Joint swelling (HP:0001386)1.71170929
165Pulmonary embolism (HP:0002204)1.70906062
166Abnormality of glutamine family amino acid metabolism (HP:0010902)1.70554300

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK35.39984653
2ERN13.96028526
3PRPF4B3.81151700
4IRAK43.72307402
5MAP3K103.02599852
6TAOK32.76236052
7MAP4K12.65333673
8TRIB32.59462787
9INSRR2.50375744
10EIF2AK32.42117321
11PLK42.39452846
12ZAK2.29391669
13STK162.20072603
14BLK2.00901599
15IRAK11.94136105
16MAP3K141.84469007
17BCKDK1.83978596
18CDK121.77342853
19IRAK21.74317787
20RIPK11.73411720
21ICK1.58123750
22BTK1.49050969
23BRD41.48846994
24NME21.45436656
25SRPK11.43016923
26TEC1.41061395
27FGFR31.40599789
28CDC42BPA1.37763945
29TYK21.37638611
30JAK31.33308819
31TLK11.32586263
32ZAP701.31440315
33SMG11.28814940
34MAP3K11.27706302
35TAOK21.27106490
36FLT31.24409108
37TXK1.23546847
38SIK11.22101237
39IKBKB1.17806895
40MAP3K111.15723086
41IKBKE1.14249054
42PRKD21.11845010
43TAOK11.08712481
44SYK1.08329044
45GRK61.06096038
46SCYL21.05361353
47EIF2AK21.04933887
48PASK1.03000921
49TBK11.02042842
50MATK1.01579979
51MAPK151.00995779
52NLK1.00428610
53EPHA20.99883259
54PDPK10.99178313
55NUAK10.96220046
56NEK90.94765744
57PIM10.94718355
58CHUK0.94135787
59ATR0.93362853
60LYN0.93253612
61FRK0.91997543
62RPS6KB20.91425859
63BUB10.90137469
64JAK10.89375961
65PDK10.89223336
66CSF1R0.88924014
67MARK20.88600135
68KDR0.87737201
69MAP2K30.86954462
70MAPKAPK30.86486540
71EPHB10.86273494
72HIPK20.80737611
73DYRK30.79690902
74STK40.78580913
75JAK20.78453364
76TRPM70.75617746
77NEK20.75008542
78PIK3CG0.74687171
79LATS10.74183960
80MAP2K20.73892478
81TTK0.71394043
82TNK20.71222370
83AKT30.70611898
84KIT0.69206719
85KSR20.68492310
86MAP3K60.67184560
87MAPK120.67112617
88SIK30.64889673
89PRKCI0.64352465
90GRK10.64186824
91TESK20.64024678
92CDK40.63465441
93BMPR20.62247800
94PDGFRA0.61532929
95PIM20.60917772
96PTK60.60579113
97DDR20.60150843
98CDC70.59939414
99SIK20.59828865
100STK100.59155518
101VRK10.58501524
102EEF2K0.57716425
103MAP3K130.56787393
104RET0.56020608
105RIPK40.55820170
106FGR0.55477865
107CSK0.54432725
108RPS6KL10.53944781
109RPS6KC10.53944781
110STK240.53177340
111MTOR0.52941330
112FGFR40.52806603
113LCK0.52774208
114MKNK20.52448982
115ITK0.51841391
116MAP3K20.51819224
117ARAF0.51717166
118RPS6KA40.51604783
119SGK30.51435341
120TTN0.51113512
121MST1R0.49515272
122PDK20.48899293
123RPS6KA20.46312307
124CHEK20.46305549
125HCK0.46141880
126YES10.46022065
127ADRBK20.44504820
128EPHA30.44302931
129WEE10.43831849
130TGFBR20.43579353
131MAPK70.42873562
132CDK70.42375317
133FES0.41875055
134MAP2K60.41774483
135PRKAA20.41694918
136LRRK20.41454959
137CDK60.41220693
138RPS6KA60.39940428
139AURKB0.38064124
140CDK90.35957635
141MAP3K80.35616708
142MARK30.35427249
143PLK10.34307604
144PKN20.33332095
145MAP3K30.30373171
146MAPK110.27467902

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.63620525
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.26622429
3Other glycan degradation_Homo sapiens_hsa005112.65742296
4Primary immunodeficiency_Homo sapiens_hsa053402.53033881
5Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.44337677
6DNA replication_Homo sapiens_hsa030302.37227599
7Allograft rejection_Homo sapiens_hsa053302.25013971
8One carbon pool by folate_Homo sapiens_hsa006702.13682100
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.08842699
10Autoimmune thyroid disease_Homo sapiens_hsa053202.05539202
11N-Glycan biosynthesis_Homo sapiens_hsa005101.98283283
12Fanconi anemia pathway_Homo sapiens_hsa034601.96420253
13Folate biosynthesis_Homo sapiens_hsa007901.94284782
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.80982272
15Non-homologous end-joining_Homo sapiens_hsa034501.78218075
16Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.76649468
17Homologous recombination_Homo sapiens_hsa034401.70954559
18Type I diabetes mellitus_Homo sapiens_hsa049401.69486239
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.67288206
20Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.62004536
21Base excision repair_Homo sapiens_hsa034101.61836876
22Selenocompound metabolism_Homo sapiens_hsa004501.60496822
23Pyrimidine metabolism_Homo sapiens_hsa002401.59280926
24Mismatch repair_Homo sapiens_hsa034301.53424303
25Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.53190853
26Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.51178864
27Glycosaminoglycan degradation_Homo sapiens_hsa005311.49500099
28B cell receptor signaling pathway_Homo sapiens_hsa046621.49214276
29Pancreatic secretion_Homo sapiens_hsa049721.39669057
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.29666391
31Leishmaniasis_Homo sapiens_hsa051401.28990700
32Fat digestion and absorption_Homo sapiens_hsa049751.28662674
33Measles_Homo sapiens_hsa051621.27189560
34Antigen processing and presentation_Homo sapiens_hsa046121.26799843
35Viral myocarditis_Homo sapiens_hsa054161.26277068
36Vitamin digestion and absorption_Homo sapiens_hsa049771.22758638
37Protein digestion and absorption_Homo sapiens_hsa049741.21331805
38Rheumatoid arthritis_Homo sapiens_hsa053231.18716904
39Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17774437
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.13474074
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.10013372
42Herpes simplex infection_Homo sapiens_hsa051681.09214227
43Ribosome_Homo sapiens_hsa030101.08415983
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02591043
45p53 signaling pathway_Homo sapiens_hsa041151.01449845
46NOD-like receptor signaling pathway_Homo sapiens_hsa046211.01193762
47Non-small cell lung cancer_Homo sapiens_hsa052231.00900763
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00732908
49Hematopoietic cell lineage_Homo sapiens_hsa046401.00672814
50Toll-like receptor signaling pathway_Homo sapiens_hsa046201.00611120
51Legionellosis_Homo sapiens_hsa051341.00347085
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.00077252
53Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99982638
54Renin-angiotensin system_Homo sapiens_hsa046140.98439207
55Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.98320349
56Osteoclast differentiation_Homo sapiens_hsa043800.98283484
57Influenza A_Homo sapiens_hsa051640.97918844
58Lysine degradation_Homo sapiens_hsa003100.94429254
59Systemic lupus erythematosus_Homo sapiens_hsa053220.94157967
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.92911583
61RNA polymerase_Homo sapiens_hsa030200.91724254
62Malaria_Homo sapiens_hsa051440.90648889
63Chronic myeloid leukemia_Homo sapiens_hsa052200.90430577
64Prion diseases_Homo sapiens_hsa050200.90206120
65Spliceosome_Homo sapiens_hsa030400.85350777
66Fructose and mannose metabolism_Homo sapiens_hsa000510.85297250
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85276152
68Sulfur relay system_Homo sapiens_hsa041220.85061763
69beta-Alanine metabolism_Homo sapiens_hsa004100.84866646
70Adipocytokine signaling pathway_Homo sapiens_hsa049200.84189978
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.84172771
72Staphylococcus aureus infection_Homo sapiens_hsa051500.82511752
73Insulin resistance_Homo sapiens_hsa049310.81869163
74Chemokine signaling pathway_Homo sapiens_hsa040620.81574169
75Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80067837
76Phagosome_Homo sapiens_hsa041450.79855802
77ABC transporters_Homo sapiens_hsa020100.79398707
78Pancreatic cancer_Homo sapiens_hsa052120.76351559
79Prolactin signaling pathway_Homo sapiens_hsa049170.75115914
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.74940869
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74194728
82Epstein-Barr virus infection_Homo sapiens_hsa051690.73005528
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.70685990
84PPAR signaling pathway_Homo sapiens_hsa033200.69772898
85VEGF signaling pathway_Homo sapiens_hsa043700.69566932
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69546597
87Bladder cancer_Homo sapiens_hsa052190.69348086
88Apoptosis_Homo sapiens_hsa042100.68806490
89Galactose metabolism_Homo sapiens_hsa000520.67988204
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.67986909
91African trypanosomiasis_Homo sapiens_hsa051430.67237793
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.65984952
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.65315118
94Amoebiasis_Homo sapiens_hsa051460.65186331
95Acute myeloid leukemia_Homo sapiens_hsa052210.65114802
96Purine metabolism_Homo sapiens_hsa002300.64831538
97Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64554311
98Phenylalanine metabolism_Homo sapiens_hsa003600.63287900
99Pertussis_Homo sapiens_hsa051330.63284383
100Cyanoamino acid metabolism_Homo sapiens_hsa004600.62698978
101Starch and sucrose metabolism_Homo sapiens_hsa005000.62290477
102RNA degradation_Homo sapiens_hsa030180.62107621
103Histidine metabolism_Homo sapiens_hsa003400.60334310
104Tryptophan metabolism_Homo sapiens_hsa003800.60071965
105Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59454696
106Toxoplasmosis_Homo sapiens_hsa051450.58623711
107Renal cell carcinoma_Homo sapiens_hsa052110.58245489
108Lysosome_Homo sapiens_hsa041420.58235359
109Cell cycle_Homo sapiens_hsa041100.58130262
110Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.57963299
111Asthma_Homo sapiens_hsa053100.57579539
112Arginine biosynthesis_Homo sapiens_hsa002200.57500706
113Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56603983
114Hepatitis B_Homo sapiens_hsa051610.56250792
115Complement and coagulation cascades_Homo sapiens_hsa046100.56157040
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.55848210
117Platelet activation_Homo sapiens_hsa046110.54849502
118Shigellosis_Homo sapiens_hsa051310.53803210
119Nucleotide excision repair_Homo sapiens_hsa034200.53457576
120Viral carcinogenesis_Homo sapiens_hsa052030.51690037
121Inositol phosphate metabolism_Homo sapiens_hsa005620.51453907
122Small cell lung cancer_Homo sapiens_hsa052220.51206819
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50795955
124Salmonella infection_Homo sapiens_hsa051320.50289826
125Hepatitis C_Homo sapiens_hsa051600.50131608
126Sphingolipid metabolism_Homo sapiens_hsa006000.49732116
127TNF signaling pathway_Homo sapiens_hsa046680.48164629
128Tuberculosis_Homo sapiens_hsa051520.47832292
129Arachidonic acid metabolism_Homo sapiens_hsa005900.46604974
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.46532828
131mTOR signaling pathway_Homo sapiens_hsa041500.46508536
132HIF-1 signaling pathway_Homo sapiens_hsa040660.46217789
133Glycerolipid metabolism_Homo sapiens_hsa005610.45927412
134Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45856535
135Pentose phosphate pathway_Homo sapiens_hsa000300.45401345
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44005052
137Peroxisome_Homo sapiens_hsa041460.43774737
138Graft-versus-host disease_Homo sapiens_hsa053320.43490889
139Sulfur metabolism_Homo sapiens_hsa009200.42604959
140FoxO signaling pathway_Homo sapiens_hsa040680.42510021
141Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42237462
142HTLV-I infection_Homo sapiens_hsa051660.42059263
143Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41589951
144T cell receptor signaling pathway_Homo sapiens_hsa046600.40666731
145Prostate cancer_Homo sapiens_hsa052150.40650532
146Endometrial cancer_Homo sapiens_hsa052130.39079659

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