TUBAP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.17048436
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.83147404
3energy coupled proton transport, down electrochemical gradient (GO:0015985)4.78073337
4ATP synthesis coupled proton transport (GO:0015986)4.78073337
5sequestering of actin monomers (GO:0042989)4.76415691
6protein complex biogenesis (GO:0070271)4.48438125
7establishment of protein localization to mitochondrial membrane (GO:0090151)4.47028624
8behavioral response to nicotine (GO:0035095)4.44914369
9mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.42402934
10mitochondrial respiratory chain complex I assembly (GO:0032981)4.42402934
11NADH dehydrogenase complex assembly (GO:0010257)4.42402934
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.27727386
13chaperone-mediated protein transport (GO:0072321)4.27191928
14nucleobase catabolic process (GO:0046113)4.23282306
15protein neddylation (GO:0045116)4.19927168
16mitochondrial respiratory chain complex assembly (GO:0033108)4.05057525
17protein-cofactor linkage (GO:0018065)3.79548732
18respiratory electron transport chain (GO:0022904)3.76052153
19electron transport chain (GO:0022900)3.74472817
20RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.35133033
21tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.35133033
22protein polyglutamylation (GO:0018095)3.29529169
23nonmotile primary cilium assembly (GO:0035058)3.17148730
24water-soluble vitamin biosynthetic process (GO:0042364)3.16524480
25cell proliferation in forebrain (GO:0021846)3.15631836
26retinal ganglion cell axon guidance (GO:0031290)3.13335765
27substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.09862048
28substrate-independent telencephalic tangential migration (GO:0021826)3.09862048
29negative regulation of telomere maintenance (GO:0032205)3.05895477
30nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.95579061
31hydrogen ion transmembrane transport (GO:1902600)2.92443992
32establishment of mitochondrion localization (GO:0051654)2.91692354
33DNA deamination (GO:0045006)2.90814317
34cullin deneddylation (GO:0010388)2.88023928
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.87450625
36DNA damage response, detection of DNA damage (GO:0042769)2.86158377
37regulation of cilium movement (GO:0003352)2.85461437
38postsynaptic membrane organization (GO:0001941)2.84885760
39platelet dense granule organization (GO:0060155)2.84756603
40somite development (GO:0061053)2.84140042
41cornea development in camera-type eye (GO:0061303)2.78200814
42negative regulation of transcription regulatory region DNA binding (GO:2000678)2.76469538
43proton transport (GO:0015992)2.74570624
44protein deneddylation (GO:0000338)2.72289491
45neuron cell-cell adhesion (GO:0007158)2.71757068
46ATP biosynthetic process (GO:0006754)2.70659499
47respiratory chain complex IV assembly (GO:0008535)2.70448049
48transmission of nerve impulse (GO:0019226)2.70348233
49regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.69736444
50gamma-aminobutyric acid transport (GO:0015812)2.69413482
51hydrogen transport (GO:0006818)2.68311604
52mannosylation (GO:0097502)2.67716658
53purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.66120877
54protein localization to cilium (GO:0061512)2.66051856
55limb bud formation (GO:0060174)2.65794051
56termination of RNA polymerase III transcription (GO:0006386)2.64084372
57transcription elongation from RNA polymerase III promoter (GO:0006385)2.64084372
58purine nucleoside triphosphate biosynthetic process (GO:0009145)2.63805068
59intracellular protein transmembrane import (GO:0044743)2.59093970
60neurofilament cytoskeleton organization (GO:0060052)2.57133473
61presynaptic membrane organization (GO:0097090)2.56103525
62positive regulation of mitochondrial fission (GO:0090141)2.55921010
63dendritic spine morphogenesis (GO:0060997)2.55596753
64epithelial cilium movement (GO:0003351)2.55553160
65proteasome assembly (GO:0043248)2.52663025
66cytochrome complex assembly (GO:0017004)2.51986381
67GTP biosynthetic process (GO:0006183)2.51748572
68preassembly of GPI anchor in ER membrane (GO:0016254)2.50959864
69presynaptic membrane assembly (GO:0097105)2.48853839
70axonal fasciculation (GO:0007413)2.48625047
71regulation of development, heterochronic (GO:0040034)2.48188728
72DNA double-strand break processing (GO:0000729)2.48122315
73organelle disassembly (GO:1903008)2.47480421
74neuron fate determination (GO:0048664)2.46126606
75cilium morphogenesis (GO:0060271)2.44538326
76neural tube formation (GO:0001841)2.44287200
77regulation of timing of cell differentiation (GO:0048505)2.42982286
78fucose catabolic process (GO:0019317)2.42365316
79L-fucose metabolic process (GO:0042354)2.42365316
80L-fucose catabolic process (GO:0042355)2.42365316
81inner mitochondrial membrane organization (GO:0007007)2.41849540
82GPI anchor metabolic process (GO:0006505)2.41569696
83neuron recognition (GO:0008038)2.41091861
84negative regulation of synaptic transmission, GABAergic (GO:0032229)2.40045664
85regulation of action potential (GO:0098900)2.39428975
86regulation of microtubule-based movement (GO:0060632)2.38762140
87synaptic transmission, cholinergic (GO:0007271)2.37656445
88ubiquinone metabolic process (GO:0006743)2.36980728
89protein localization to mitochondrion (GO:0070585)2.36033857
90forebrain neuron differentiation (GO:0021879)2.34958469
91tRNA processing (GO:0008033)2.33600825
92synapse assembly (GO:0007416)2.33120552
93ribonucleoside triphosphate biosynthetic process (GO:0009201)2.32654654
94regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.32616221
95intraciliary transport (GO:0042073)2.32161937
96L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.31776770
97establishment of protein localization to mitochondrion (GO:0072655)2.31763739
98resolution of meiotic recombination intermediates (GO:0000712)2.31590512
99olfactory bulb development (GO:0021772)2.31309890
100hindbrain development (GO:0030902)2.30853642

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.35850315
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.18198675
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.11727871
4ZNF274_21170338_ChIP-Seq_K562_Hela3.07444581
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.06049651
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98244365
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.81886514
8VDR_22108803_ChIP-Seq_LS180_Human2.69830115
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.65836388
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.39272018
11GBX2_23144817_ChIP-Seq_PC3_Human2.35168793
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.27710250
13TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.25938040
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.20224477
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.11538312
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.95531819
17TAF15_26573619_Chip-Seq_HEK293_Human1.95224486
18IGF1R_20145208_ChIP-Seq_DFB_Human1.91348308
19EWS_26573619_Chip-Seq_HEK293_Human1.89799152
20BMI1_23680149_ChIP-Seq_NPCS_Mouse1.89281195
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.87896625
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83975380
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.83788029
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.81058551
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.78030424
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77904563
27FUS_26573619_Chip-Seq_HEK293_Human1.76387257
28RNF2_27304074_Chip-Seq_NSC_Mouse1.72308484
29REST_21632747_ChIP-Seq_MESCs_Mouse1.69826387
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.66991138
31POU5F1_16153702_ChIP-ChIP_HESCs_Human1.65099750
32P300_19829295_ChIP-Seq_ESCs_Human1.63327532
33EZH2_27304074_Chip-Seq_ESCs_Mouse1.62338429
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61755865
35MYC_18940864_ChIP-ChIP_HL60_Human1.61701321
36ELK1_19687146_ChIP-ChIP_HELA_Human1.60060195
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.55420188
38EED_16625203_ChIP-ChIP_MESCs_Mouse1.53575360
39IRF1_19129219_ChIP-ChIP_H3396_Human1.50860999
40CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.47637045
41MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.46011710
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.45406149
43VDR_23849224_ChIP-Seq_CD4+_Human1.42504217
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40461560
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38434531
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.38073175
47TP53_22573176_ChIP-Seq_HFKS_Human1.35605444
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.34323324
49CREB1_15753290_ChIP-ChIP_HEK293T_Human1.32363568
50PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32305194
51SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.30799530
52SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.27545809
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26499603
54GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.26155231
55SOX2_16153702_ChIP-ChIP_HESCs_Human1.21825783
56UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20240615
57FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18874787
58YY1_21170310_ChIP-Seq_MESCs_Mouse1.14945429
59RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14836737
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14065994
61TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13323091
62POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13323091
63PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.10490464
64EZH2_27294783_Chip-Seq_ESCs_Mouse1.09866172
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09691764
66CBP_20019798_ChIP-Seq_JUKART_Human1.09604499
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.09604499
68SRF_21415370_ChIP-Seq_HL-1_Mouse1.09585743
69ER_23166858_ChIP-Seq_MCF-7_Human1.06356624
70ETV2_25802403_ChIP-Seq_MESCs_Mouse1.04971729
71PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.04857675
72MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.04794347
73AR_25329375_ChIP-Seq_VCAP_Human1.04106071
74NCOR_22424771_ChIP-Seq_293T_Human1.02484558
75JARID2_20075857_ChIP-Seq_MESCs_Mouse1.02280092
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01848815
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.01616617
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01104429
79FOXP3_21729870_ChIP-Seq_TREG_Human1.00646734
80SMAD4_21799915_ChIP-Seq_A2780_Human1.00556786
81SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99953563
82KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99789810
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97139647
84SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.97134166
85SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.97081969
86THAP11_20581084_ChIP-Seq_MESCs_Mouse0.97025213
87NOTCH1_21737748_ChIP-Seq_TLL_Human0.96570300
88ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96489214
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.95201545
90PCGF2_27294783_Chip-Seq_NPCs_Mouse0.94837788
91NANOG_19829295_ChIP-Seq_ESCs_Human0.92048848
92SOX2_19829295_ChIP-Seq_ESCs_Human0.92048848
93TTF2_22483619_ChIP-Seq_HELA_Human0.91851765
94GABP_19822575_ChIP-Seq_HepG2_Human0.91614020
95TP63_19390658_ChIP-ChIP_HaCaT_Human0.91559008
96FOXA1_25329375_ChIP-Seq_VCAP_Human0.91371150
97FOXA1_27270436_Chip-Seq_PROSTATE_Human0.91371150
98SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.90250092
99PIAS1_25552417_ChIP-Seq_VCAP_Human0.86280984
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.85931054

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.17801446
2MP0003880_abnormal_central_pattern2.98980216
3MP0003787_abnormal_imprinting2.98079990
4MP0003122_maternal_imprinting2.67444296
5MP0008877_abnormal_DNA_methylation2.56090306
6MP0002102_abnormal_ear_morphology2.52349402
7MP0001529_abnormal_vocalization2.42806030
8MP0006276_abnormal_autonomic_nervous2.26070140
9MP0003121_genomic_imprinting2.24804756
10MP0008789_abnormal_olfactory_epithelium2.22075863
11MP0002638_abnormal_pupillary_reflex2.18911654
12MP0000778_abnormal_nervous_system2.09595752
13MP0006072_abnormal_retinal_apoptosis2.06304873
14MP0002938_white_spotting2.03137842
15MP0005499_abnormal_olfactory_system1.99658526
16MP0005394_taste/olfaction_phenotype1.99658526
17MP0004142_abnormal_muscle_tone1.98901760
18MP0001968_abnormal_touch/_nociception1.92789859
19MP0002653_abnormal_ependyma_morphology1.91431195
20MP0001984_abnormal_olfaction1.86211958
21MP0003011_delayed_dark_adaptation1.84656236
22MP0002272_abnormal_nervous_system1.81890510
23MP0002736_abnormal_nociception_after1.81308461
24MP0005423_abnormal_somatic_nervous1.81064158
25MP0009745_abnormal_behavioral_response1.79333063
26MP0009046_muscle_twitch1.75394958
27MP0005645_abnormal_hypothalamus_physiol1.69708662
28MP0002837_dystrophic_cardiac_calcinosis1.69463104
29MP0005551_abnormal_eye_electrophysiolog1.69412318
30MP0005084_abnormal_gallbladder_morpholo1.63605449
31MP0004885_abnormal_endolymph1.63569678
32MP0002822_catalepsy1.62203429
33MP0000631_abnormal_neuroendocrine_gland1.59804163
34MP0001905_abnormal_dopamine_level1.58127456
35MP0002184_abnormal_innervation1.57929640
36MP0003635_abnormal_synaptic_transmissio1.54901768
37MP0002572_abnormal_emotion/affect_behav1.54128805
38MP0000049_abnormal_middle_ear1.52153812
39MP0004133_heterotaxia1.49480984
40MP0005253_abnormal_eye_physiology1.48179065
41MP0002557_abnormal_social/conspecific_i1.45864678
42MP0001986_abnormal_taste_sensitivity1.44507804
43MP0000569_abnormal_digit_pigmentation1.43257981
44MP0002063_abnormal_learning/memory/cond1.39839877
45MP0002735_abnormal_chemical_nociception1.36367524
46MP0001486_abnormal_startle_reflex1.35356007
47MP0002751_abnormal_autonomic_nervous1.35110077
48MP0000955_abnormal_spinal_cord1.34832874
49MP0004859_abnormal_synaptic_plasticity1.33926886
50MP0005646_abnormal_pituitary_gland1.33346998
51MP0002234_abnormal_pharynx_morphology1.32769282
52MP0002733_abnormal_thermal_nociception1.32590054
53MP0002064_seizures1.31655639
54MP0002734_abnormal_mechanical_nocicepti1.31600915
55MP0001970_abnormal_pain_threshold1.31096360
56MP0001485_abnormal_pinna_reflex1.31055582
57MP0002163_abnormal_gland_morphology1.30710243
58MP0008995_early_reproductive_senescence1.26537176
59MP0002752_abnormal_somatic_nervous1.23343894
60MP0004270_analgesia1.22946984
61MP0004742_abnormal_vestibular_system1.20941534
62MP0002067_abnormal_sensory_capabilities1.20830292
63MP0003136_yellow_coat_color1.20325508
64MP0001188_hyperpigmentation1.17704032
65MP0001293_anophthalmia1.17161527
66MP0004145_abnormal_muscle_electrophysio1.17137789
67MP0000372_irregular_coat_pigmentation1.15868545
68MP0000566_synostosis1.14717106
69MP0001440_abnormal_grooming_behavior1.12851245
70MP0003890_abnormal_embryonic-extraembry1.12577815
71MP0008872_abnormal_physiological_respon1.12356246
72MP0005195_abnormal_posterior_eye1.09135576
73MP0000026_abnormal_inner_ear1.08262861
74MP0002882_abnormal_neuron_morphology1.07731453
75MP0003938_abnormal_ear_development0.99347644
76MP0008058_abnormal_DNA_repair0.99289899
77MP0009379_abnormal_foot_pigmentation0.98932388
78MP0004924_abnormal_behavior0.97972173
79MP0005386_behavior/neurological_phenoty0.97972173
80MP0002160_abnormal_reproductive_system0.95734730
81MP0003718_maternal_effect0.95335310
82MP0005379_endocrine/exocrine_gland_phen0.94775778
83MP0004811_abnormal_neuron_physiology0.94249461
84MP0003937_abnormal_limbs/digits/tail_de0.93172001
85MP0003195_calcinosis0.90426562
86MP0001502_abnormal_circadian_rhythm0.88351806
87MP0002876_abnormal_thyroid_physiology0.87855212
88MP0002233_abnormal_nose_morphology0.87705777
89MP0005389_reproductive_system_phenotype0.87347720
90MP0002909_abnormal_adrenal_gland0.86967198
91MP0003283_abnormal_digestive_organ0.86904243
92MP0003119_abnormal_digestive_system0.86375453
93MP0004147_increased_porphyrin_level0.85650065
94MP0001286_abnormal_eye_development0.84175772
95MP0001963_abnormal_hearing_physiology0.83440188
96MP0002152_abnormal_brain_morphology0.83036356
97MP0008875_abnormal_xenobiotic_pharmacok0.82905236
98MP0000647_abnormal_sebaceous_gland0.80391819
99MP0002277_abnormal_respiratory_mucosa0.80023221
100MP0005391_vision/eye_phenotype0.79789627

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.36893181
2Abnormal mitochondria in muscle tissue (HP:0008316)3.87180017
3Acute encephalopathy (HP:0006846)3.70240016
4Progressive macrocephaly (HP:0004481)3.68490393
5Mitochondrial inheritance (HP:0001427)3.68207131
6True hermaphroditism (HP:0010459)3.52374299
7Pancreatic cysts (HP:0001737)3.51265866
8Pancreatic fibrosis (HP:0100732)3.48674089
9Abnormality of the labia minora (HP:0012880)3.36910172
10Abnormality of midbrain morphology (HP:0002418)3.34804109
11Molar tooth sign on MRI (HP:0002419)3.34804109
12Increased CSF lactate (HP:0002490)3.31708045
13Hepatocellular necrosis (HP:0001404)3.10317809
14Nephronophthisis (HP:0000090)3.03253673
15Medial flaring of the eyebrow (HP:0010747)3.00813841
16Hepatic necrosis (HP:0002605)2.99376725
17Limb dystonia (HP:0002451)2.86385043
18Septo-optic dysplasia (HP:0100842)2.85564017
19Lissencephaly (HP:0001339)2.85048729
20Gait imbalance (HP:0002141)2.82394251
21Increased hepatocellular lipid droplets (HP:0006565)2.80212414
22Polyphagia (HP:0002591)2.67974422
23Lipid accumulation in hepatocytes (HP:0006561)2.64587609
24Cerebral edema (HP:0002181)2.57535497
25Type II lissencephaly (HP:0007260)2.57364022
263-Methylglutaconic aciduria (HP:0003535)2.56514829
27Pendular nystagmus (HP:0012043)2.54870592
28Sclerocornea (HP:0000647)2.51802665
29Optic disc pallor (HP:0000543)2.50578651
30Optic nerve hypoplasia (HP:0000609)2.50014967
31Congenital primary aphakia (HP:0007707)2.48860028
32Pachygyria (HP:0001302)2.48604357
33Methylmalonic acidemia (HP:0002912)2.44912108
34Nephrogenic diabetes insipidus (HP:0009806)2.44513370
35Congenital stationary night blindness (HP:0007642)2.44391136
36Abnormality of the renal medulla (HP:0100957)2.41088647
37Myokymia (HP:0002411)2.36753210
38Renal Fanconi syndrome (HP:0001994)2.34490134
39Retinal dysplasia (HP:0007973)2.32736568
40Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.29789951
41Anencephaly (HP:0002323)2.22136904
42Poor suck (HP:0002033)2.18631880
43Hyperglycinemia (HP:0002154)2.17711023
44Abolished electroretinogram (ERG) (HP:0000550)2.16218434
45Genital tract atresia (HP:0001827)2.13129157
46Vaginal atresia (HP:0000148)2.12470353
47Abnormality of the renal cortex (HP:0011035)2.12012594
48Cystic liver disease (HP:0006706)2.11763640
49Increased serum lactate (HP:0002151)2.11580132
50Abnormal rod and cone electroretinograms (HP:0008323)2.11381943
51Renal cortical cysts (HP:0000803)2.09656774
52Agitation (HP:0000713)2.08753363
53Colon cancer (HP:0003003)2.05349363
54Methylmalonic aciduria (HP:0012120)2.03981564
55Hypothermia (HP:0002045)2.02325216
56Aplasia/Hypoplasia of the tongue (HP:0010295)2.01818104
57Absent rod-and cone-mediated responses on ERG (HP:0007688)2.01204009
58Oligodactyly (hands) (HP:0001180)2.00648103
59Lactic acidosis (HP:0003128)1.99424000
60Leukodystrophy (HP:0002415)1.98863460
61Focal motor seizures (HP:0011153)1.98422342
62Absent septum pellucidum (HP:0001331)1.97832466
63Aplasia/Hypoplasia of the brainstem (HP:0007362)1.96664517
64Hypoplasia of the brainstem (HP:0002365)1.96664517
65Male pseudohermaphroditism (HP:0000037)1.94458808
66Chronic hepatic failure (HP:0100626)1.90377010
67Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.90046805
68Decreased activity of mitochondrial respiratory chain (HP:0008972)1.90046805
69Congenital, generalized hypertrichosis (HP:0004540)1.89872386
70Generalized aminoaciduria (HP:0002909)1.88394606
71Inability to walk (HP:0002540)1.87865703
72Respiratory failure (HP:0002878)1.87119152
73Hypoplastic pelvis (HP:0008839)1.84098406
74Postaxial hand polydactyly (HP:0001162)1.83367883
75Broad-based gait (HP:0002136)1.81488231
76Specific learning disability (HP:0001328)1.80985563
77Decreased electroretinogram (ERG) amplitude (HP:0000654)1.78944490
78Short tibia (HP:0005736)1.78731981
79Aplasia/hypoplasia of the uterus (HP:0008684)1.78380293
80Anophthalmia (HP:0000528)1.77851525
81Growth hormone deficiency (HP:0000824)1.77208846
82Postaxial foot polydactyly (HP:0001830)1.77043319
83Glycosuria (HP:0003076)1.76823476
84Abnormality of urine glucose concentration (HP:0011016)1.76823476
85Hyperventilation (HP:0002883)1.76578625
86Abnormal number of erythroid precursors (HP:0012131)1.76104751
87Narrow forehead (HP:0000341)1.75947060
88Occipital encephalocele (HP:0002085)1.72429238
89Abnormality of alanine metabolism (HP:0010916)1.71821496
90Hyperalaninemia (HP:0003348)1.71821496
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.71821496
92Increased intramyocellular lipid droplets (HP:0012240)1.71596003
93Exertional dyspnea (HP:0002875)1.71385406
94Optic nerve coloboma (HP:0000588)1.71131100
95Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.70418236
96Aplasia/Hypoplasia of the tibia (HP:0005772)1.69553142
97Abnormality of renal resorption (HP:0011038)1.69528799
98Abnormality of cells of the erythroid lineage (HP:0012130)1.69413630
99Lethargy (HP:0001254)1.68839964
100Progressive cerebellar ataxia (HP:0002073)1.68695111

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK33.32313014
2MARK13.25774178
3CASK2.85873653
4MAP4K22.80652530
5DYRK22.72621967
6MAPK132.41334637
7MAP2K72.35620349
8MAP3K42.26838001
9ZAK2.21735112
10STK162.17868605
11VRK22.14730960
12ADRBK22.06108978
13BCR1.94385937
14FRK1.91800110
15TRIM281.82101356
16GRK11.74017443
17TLK11.67103682
18VRK11.65925954
19CSNK1G21.64970943
20WNK41.63923583
21BMPR1B1.62698273
22PINK11.62570971
23NUAK11.62262572
24CSNK1G31.54156013
25BUB11.48900615
26MINK11.43143012
27PAK31.35400743
28CSNK1G11.32496524
29SRPK11.32281407
30PHKG11.30371672
31PHKG21.30371672
32BCKDK1.25389721
33EPHB21.25215902
34PRKCG1.23483920
35NTRK21.23010373
36CSNK1A1L1.22290669
37TSSK61.20587180
38INSRR1.17799308
39ERBB31.08896600
40TNIK1.06504686
41PNCK1.05037337
42LIMK11.02449508
43DYRK31.02127869
44NME11.02086408
45PLK30.99297854
46EPHA40.97637306
47TIE10.97628594
48UHMK10.93962303
49SIK20.93647588
50PLK20.93422880
51OXSR10.87914196
52PRKCE0.85115941
53CDK190.81740101
54NEK10.81412025
55TAOK30.79935314
56MKNK20.73853781
57PKN10.72943498
58ADRBK10.72106623
59STK390.69669968
60NTRK30.69061964
61MAP2K40.66746114
62CAMK2A0.64108570
63TAF10.63872296
64RPS6KA50.63037933
65CDC70.62981007
66WEE10.62903395
67RPS6KA40.62109268
68MKNK10.61752241
69CCNB10.59697050
70PLK10.58895076
71DYRK1A0.57784984
72CSNK1A10.57648517
73PRKACA0.57418757
74GRK70.52342768
75PLK40.52095263
76STK38L0.51217319
77AURKA0.50900386
78CAMKK20.49766059
79CSNK1E0.48514838
80DAPK20.47168256
81EIF2AK30.45711667
82CDK140.44773290
83TXK0.43678420
84CSNK2A10.42610579
85PAK60.42196451
86ATR0.41578965
87CDK50.41507949
88MAPK150.40116427
89MST40.39352675
90CSNK2A20.39264247
91PRKCZ0.37870125
92DYRK1B0.36737524
93MAP3K120.36147119
94SGK4940.35871082
95SGK2230.35871082
96PRKG10.34464318
97CDK180.33969162
98PRKCI0.33503540
99AURKB0.33432134
100CHEK20.32665798

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001904.41249189
2Parkinsons disease_Homo sapiens_hsa050123.72221205
3Protein export_Homo sapiens_hsa030603.33246021
4Proteasome_Homo sapiens_hsa030502.76573904
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.72385930
6Huntingtons disease_Homo sapiens_hsa050162.50725127
7Alzheimers disease_Homo sapiens_hsa050102.48922699
8Ribosome_Homo sapiens_hsa030102.37842698
9Nicotine addiction_Homo sapiens_hsa050332.36832686
10Cardiac muscle contraction_Homo sapiens_hsa042602.34639738
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.28813506
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.24179603
13RNA polymerase_Homo sapiens_hsa030202.22767961
14Phototransduction_Homo sapiens_hsa047442.08471680
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.02878568
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.02462831
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.89031989
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.88626878
19Steroid biosynthesis_Homo sapiens_hsa001001.88130890
20Butanoate metabolism_Homo sapiens_hsa006501.78594865
21Basal transcription factors_Homo sapiens_hsa030221.62366721
22Collecting duct acid secretion_Homo sapiens_hsa049661.45559690
23RNA degradation_Homo sapiens_hsa030181.38534784
24GABAergic synapse_Homo sapiens_hsa047271.37385791
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28131944
26Morphine addiction_Homo sapiens_hsa050321.26749478
27Fanconi anemia pathway_Homo sapiens_hsa034601.22245160
28Propanoate metabolism_Homo sapiens_hsa006401.16809809
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.11155385
30Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.08008172
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07846213
32Homologous recombination_Homo sapiens_hsa034401.06240163
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.05163843
34Linoleic acid metabolism_Homo sapiens_hsa005911.03335204
35One carbon pool by folate_Homo sapiens_hsa006701.01218406
36Spliceosome_Homo sapiens_hsa030401.00862476
37Mismatch repair_Homo sapiens_hsa034300.98261379
38Taste transduction_Homo sapiens_hsa047420.96783132
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96689920
40Synaptic vesicle cycle_Homo sapiens_hsa047210.96070361
41Pyrimidine metabolism_Homo sapiens_hsa002400.94660039
42Tryptophan metabolism_Homo sapiens_hsa003800.93057762
43Peroxisome_Homo sapiens_hsa041460.91644336
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.90877897
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86113565
46Olfactory transduction_Homo sapiens_hsa047400.84246200
47Nitrogen metabolism_Homo sapiens_hsa009100.83839191
48Circadian entrainment_Homo sapiens_hsa047130.83077373
49RNA transport_Homo sapiens_hsa030130.81903918
50Dopaminergic synapse_Homo sapiens_hsa047280.80614632
51Glutamatergic synapse_Homo sapiens_hsa047240.80167123
52Fatty acid elongation_Homo sapiens_hsa000620.79243111
53Insulin secretion_Homo sapiens_hsa049110.78761990
54Purine metabolism_Homo sapiens_hsa002300.74653062
55Ether lipid metabolism_Homo sapiens_hsa005650.74468126
56Metabolic pathways_Homo sapiens_hsa011000.74239071
57Regulation of autophagy_Homo sapiens_hsa041400.74145310
58Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.72799448
59Folate biosynthesis_Homo sapiens_hsa007900.72428917
60Serotonergic synapse_Homo sapiens_hsa047260.71923673
61Cocaine addiction_Homo sapiens_hsa050300.68586110
62Sulfur relay system_Homo sapiens_hsa041220.68327804
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67229919
64Nucleotide excision repair_Homo sapiens_hsa034200.65855812
65Sulfur metabolism_Homo sapiens_hsa009200.64273496
66Selenocompound metabolism_Homo sapiens_hsa004500.62107501
67Base excision repair_Homo sapiens_hsa034100.62020174
68beta-Alanine metabolism_Homo sapiens_hsa004100.61310124
69Caffeine metabolism_Homo sapiens_hsa002320.58084413
70Pyruvate metabolism_Homo sapiens_hsa006200.57749211
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.56517369
72Alcoholism_Homo sapiens_hsa050340.55089147
73Axon guidance_Homo sapiens_hsa043600.53365054
74Retinol metabolism_Homo sapiens_hsa008300.53237696
75Chemical carcinogenesis_Homo sapiens_hsa052040.50576465
76Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.49287786
77Hedgehog signaling pathway_Homo sapiens_hsa043400.48567339
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48340626
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48243415
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46853305
81Vibrio cholerae infection_Homo sapiens_hsa051100.45091248
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.42534880
83Amphetamine addiction_Homo sapiens_hsa050310.42350738
84Oocyte meiosis_Homo sapiens_hsa041140.40888118
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.40791990
86DNA replication_Homo sapiens_hsa030300.40325448
87Fat digestion and absorption_Homo sapiens_hsa049750.40180047
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38936717
89Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.37714955
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35235036
91Basal cell carcinoma_Homo sapiens_hsa052170.34975926
92Asthma_Homo sapiens_hsa053100.34357851
93Vitamin B6 metabolism_Homo sapiens_hsa007500.33020169
94Glutathione metabolism_Homo sapiens_hsa004800.32834757
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32196754
96Salivary secretion_Homo sapiens_hsa049700.31730688
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.31354945
98Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28689585
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28610533
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27934934

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »