TTC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.32864088
2viral mRNA export from host cell nucleus (GO:0046784)4.13295741
3epithelial cilium movement (GO:0003351)4.02975037
4establishment of integrated proviral latency (GO:0075713)3.63173878
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.57075552
6cilium movement (GO:0003341)3.54171126
7peptidyl-histidine modification (GO:0018202)3.52996955
8histone H2A acetylation (GO:0043968)3.51601461
9cullin deneddylation (GO:0010388)3.45876548
10protein neddylation (GO:0045116)3.35554787
11RNA capping (GO:0036260)3.34127681
127-methylguanosine RNA capping (GO:0009452)3.34127681
137-methylguanosine mRNA capping (GO:0006370)3.33323845
14DNA strand renaturation (GO:0000733)3.32012411
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.25327755
16protein deneddylation (GO:0000338)3.25268928
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.19971667
18transcription elongation from RNA polymerase III promoter (GO:0006385)3.19190340
19termination of RNA polymerase III transcription (GO:0006386)3.19190340
20retinal cone cell development (GO:0046549)3.18660190
21nonmotile primary cilium assembly (GO:0035058)3.17297048
22neural tube formation (GO:0001841)3.17056835
23platelet dense granule organization (GO:0060155)3.15370252
24regulation of cilium movement (GO:0003352)3.15332107
25protein polyglutamylation (GO:0018095)3.14984426
26maturation of SSU-rRNA (GO:0030490)3.14529980
27energy coupled proton transport, down electrochemical gradient (GO:0015985)3.14323612
28ATP synthesis coupled proton transport (GO:0015986)3.14323612
29positive regulation of mitochondrial fission (GO:0090141)3.13820839
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.13585119
31establishment of viral latency (GO:0019043)3.13482420
32proteasome assembly (GO:0043248)3.11471355
33DNA ligation (GO:0006266)3.10712303
34tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.10220441
35RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.10220441
36pyrimidine nucleobase catabolic process (GO:0006208)3.09034192
37behavioral response to nicotine (GO:0035095)3.08064574
38cilium organization (GO:0044782)3.08017172
39cilium assembly (GO:0042384)3.04837160
40cilium morphogenesis (GO:0060271)3.02207571
41DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.00985601
42preassembly of GPI anchor in ER membrane (GO:0016254)2.99941370
43negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.99636167
44negative regulation of ligase activity (GO:0051352)2.99636167
45cilium or flagellum-dependent cell motility (GO:0001539)2.99314655
46somatic diversification of immune receptors via somatic mutation (GO:0002566)2.96922391
47somatic hypermutation of immunoglobulin genes (GO:0016446)2.96922391
48ribosomal small subunit biogenesis (GO:0042274)2.96224005
49protein complex biogenesis (GO:0070271)2.95935801
50centriole replication (GO:0007099)2.95814600
51mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.95565129
52mitochondrial respiratory chain complex I assembly (GO:0032981)2.95565129
53NADH dehydrogenase complex assembly (GO:0010257)2.95565129
54signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.95356164
55intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.95356164
56chromatin remodeling at centromere (GO:0031055)2.94886339
57DNA integration (GO:0015074)2.94553213
58signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.94009760
59signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.94009760
60signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.94009760
61transcription-coupled nucleotide-excision repair (GO:0006283)2.93266554
62CENP-A containing nucleosome assembly (GO:0034080)2.92243347
63signal transduction involved in cell cycle checkpoint (GO:0072395)2.92106696
64intraciliary transport (GO:0042073)2.91453161
65response to pheromone (GO:0019236)2.91096308
66establishment of protein localization to mitochondrial membrane (GO:0090151)2.90701717
67chaperone-mediated protein transport (GO:0072321)2.90101144
68telomere maintenance via semi-conservative replication (GO:0032201)2.89147439
69positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.89121968
70regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89031345
71regulation of mitotic spindle checkpoint (GO:1903504)2.89031345
72regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.88682934
73ubiquinone metabolic process (GO:0006743)2.88356558
74negative regulation of microtubule polymerization (GO:0031115)2.87561485
75base-excision repair, AP site formation (GO:0006285)2.87182833
76presynaptic membrane assembly (GO:0097105)2.83365351
77signal transduction involved in DNA damage checkpoint (GO:0072422)2.82354366
78signal transduction involved in DNA integrity checkpoint (GO:0072401)2.82354366
79axonemal dynein complex assembly (GO:0070286)2.81396056
80ubiquinone biosynthetic process (GO:0006744)2.79936437
81axoneme assembly (GO:0035082)2.79199391
82negative regulation of DNA-dependent DNA replication (GO:2000104)2.78855996
83DNA damage response, detection of DNA damage (GO:0042769)2.78838952
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.78549343
85piRNA metabolic process (GO:0034587)2.77941511
86gamma-aminobutyric acid transport (GO:0015812)2.77231847
87pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.76168531
88DNA strand elongation involved in DNA replication (GO:0006271)2.75899816
89regulation of helicase activity (GO:0051095)2.72889753
90antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.72585158
91organelle disassembly (GO:1903008)2.72437430
92viral protein processing (GO:0019082)2.71483757
93regulation of cellular amino acid metabolic process (GO:0006521)2.69544617
94mitochondrial respiratory chain complex assembly (GO:0033108)2.69063127
95DNA strand elongation (GO:0022616)2.67474005
96nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.67245402
97RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.67009016
98transcription elongation from RNA polymerase II promoter (GO:0006368)2.66041321
99cotranslational protein targeting to membrane (GO:0006613)2.65522922
100microtubule depolymerization (GO:0007019)2.65436091
101regulation of meiosis I (GO:0060631)2.65209015
102exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.63808325
103spliceosomal complex assembly (GO:0000245)2.63764887
104spliceosomal snRNP assembly (GO:0000387)2.61808826
105positive regulation of histone H3-K4 methylation (GO:0051571)2.61175730
106SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.61046836
107water-soluble vitamin biosynthetic process (GO:0042364)2.60457604
108nucleotide-excision repair, DNA gap filling (GO:0006297)2.60446629
109viral transcription (GO:0019083)2.60289537
110reciprocal DNA recombination (GO:0035825)2.59230640
111reciprocal meiotic recombination (GO:0007131)2.59230640
112negative regulation of DNA recombination (GO:0045910)2.58650635
113DNA double-strand break processing (GO:0000729)2.56661115
114DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.56149145
115kinetochore assembly (GO:0051382)2.55217802
116nucleobase catabolic process (GO:0046113)2.54912205
117deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.54154529
118protein targeting to ER (GO:0045047)2.54094713
119mannosylation (GO:0097502)2.53597796
120transcription elongation from RNA polymerase I promoter (GO:0006362)2.52540251
121de novo posttranslational protein folding (GO:0051084)2.52184644
122synapsis (GO:0007129)2.52088005
123telomere maintenance via recombination (GO:0000722)2.52078646
124replication fork processing (GO:0031297)2.52030677
125limb bud formation (GO:0060174)2.51840629
126DNA catabolic process, exonucleolytic (GO:0000738)2.51557748
127antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.51244374
128DNA methylation involved in gamete generation (GO:0043046)2.50995482
129protein K11-linked ubiquitination (GO:0070979)2.50880790
130peroxisome fission (GO:0016559)2.49961716
131histone exchange (GO:0043486)2.49190191
132protein K6-linked ubiquitination (GO:0085020)2.49131388
133pseudouridine synthesis (GO:0001522)2.48741725
134DNA-templated transcription, elongation (GO:0006354)2.47888304
135protein localization to cilium (GO:0061512)2.47644074
136tRNA processing (GO:0008033)2.46428019
137DNA deamination (GO:0045006)2.46178153
138negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.45688675
139translational termination (GO:0006415)2.45316453
140positive regulation of viral transcription (GO:0050434)2.45160717
141photoreceptor cell maintenance (GO:0045494)2.45103718
142recombinational repair (GO:0000725)2.44815085
143respiratory chain complex IV assembly (GO:0008535)2.44523785
144protein localization to endoplasmic reticulum (GO:0070972)2.42815167
145double-strand break repair via homologous recombination (GO:0000724)2.41720037
146single strand break repair (GO:0000012)2.41561588
147intracellular transport of virus (GO:0075733)2.41561377
148multi-organism transport (GO:0044766)2.41561377
149multi-organism localization (GO:1902579)2.41561377
150multi-organism intracellular transport (GO:1902583)2.41561377
151transport of virus (GO:0046794)2.41561377
152intracellular protein transmembrane import (GO:0044743)2.41546229
153de novo protein folding (GO:0006458)2.41195098
154protein-cofactor linkage (GO:0018065)2.41106981
155negative regulation of telomere maintenance (GO:0032205)2.40238930
156GPI anchor metabolic process (GO:0006505)2.40165705
157positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.40095730
158formation of translation preinitiation complex (GO:0001731)2.39946733
159negative regulation of transcription regulatory region DNA binding (GO:2000678)2.39498846
160histone mRNA metabolic process (GO:0008334)2.39356867
161L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.38310845
162iron-sulfur cluster assembly (GO:0016226)2.38113937
163metallo-sulfur cluster assembly (GO:0031163)2.38113937
164establishment of protein localization to endoplasmic reticulum (GO:0072599)2.37400051
165maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.37086627
166fucose catabolic process (GO:0019317)2.36373427
167L-fucose metabolic process (GO:0042354)2.36373427
168L-fucose catabolic process (GO:0042355)2.36373427
169nucleotide-excision repair (GO:0006289)2.36371696
170mitotic recombination (GO:0006312)2.36162184
171presynaptic membrane organization (GO:0097090)2.32860298
172C-terminal protein lipidation (GO:0006501)2.31468466
173C-terminal protein amino acid modification (GO:0018410)2.30833880
174maturation of 5.8S rRNA (GO:0000460)2.27860475
175meiotic cell cycle (GO:0051321)2.27780115

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.49825581
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.78958224
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.74376804
4HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.72248840
5ELF1_17652178_ChIP-ChIP_JURKAT_Human3.64626738
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.59378316
7ZNF274_21170338_ChIP-Seq_K562_Hela3.42346032
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.31140133
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.22747379
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.98194393
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.97275389
12IGF1R_20145208_ChIP-Seq_DFB_Human2.90713724
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.87933239
14EZH2_22144423_ChIP-Seq_EOC_Human2.85067631
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.82253368
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.72439039
17THAP11_20581084_ChIP-Seq_MESCs_Mouse2.54535421
18* VDR_23849224_ChIP-Seq_CD4+_Human2.37997061
19VDR_22108803_ChIP-Seq_LS180_Human2.33645916
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.33524540
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.32218182
22EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.23636191
23PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.22519673
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.20406268
25CREB1_15753290_ChIP-ChIP_HEK293T_Human2.20131169
26* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.13754238
27MYC_18358816_ChIP-ChIP_MESCs_Mouse2.13511062
28FOXP3_21729870_ChIP-Seq_TREG_Human2.12622802
29SALL1_21062744_ChIP-ChIP_HESCs_Human2.11184288
30ELK1_19687146_ChIP-ChIP_HELA_Human2.10248550
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.08161915
32RBPJ_22232070_ChIP-Seq_NCS_Mouse2.06083326
33SRF_21415370_ChIP-Seq_HL-1_Mouse2.05299529
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.04662549
35YY1_21170310_ChIP-Seq_MESCs_Mouse2.01532344
36XRN2_22483619_ChIP-Seq_HELA_Human2.00049707
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.97230892
38* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.95646833
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.95247676
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.93968411
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.85969106
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.82903976
43* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.81730292
44P300_19829295_ChIP-Seq_ESCs_Human1.80319850
45* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.79629942
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.78855573
47DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.77932123
48TTF2_22483619_ChIP-Seq_HELA_Human1.77785894
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.75711301
50CIITA_25753668_ChIP-Seq_RAJI_Human1.75561360
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.74924012
52GABP_19822575_ChIP-Seq_HepG2_Human1.72712409
53* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.69672687
54DCP1A_22483619_ChIP-Seq_HELA_Human1.66739156
55MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.62679067
56SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.61475427
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60792979
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57205183
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.56577290
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.52726420
61SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.49182085
62IRF1_19129219_ChIP-ChIP_H3396_Human1.48316004
63POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.44307637
64EWS_26573619_Chip-Seq_HEK293_Human1.44259214
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.41923007
66CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40009644
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.39815208
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.38189512
69PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35839925
70TP53_22573176_ChIP-Seq_HFKS_Human1.35072676
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.32321521
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31328440
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30609579
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30287074
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27481432
76UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27141315
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.27112731
78TP63_19390658_ChIP-ChIP_HaCaT_Human1.26561137
79EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25046338
80E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.24901104
81SMAD4_21799915_ChIP-Seq_A2780_Human1.24790195
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24158094
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.24000615
84IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.23640578
85AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23640434
86CBP_20019798_ChIP-Seq_JUKART_Human1.23232651
87IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23232651
88FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.23179124
89SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21803948
90ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14115641
91POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13823893
92SOX2_16153702_ChIP-ChIP_HESCs_Human1.11797656
93CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.11408012
94PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10095108
95KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10018503
96TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09265505
97OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09029883
98KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.08911352
99FUS_26573619_Chip-Seq_HEK293_Human1.07646184
100MYCN_18555785_ChIP-Seq_MESCs_Mouse1.06304958
101AR_25329375_ChIP-Seq_VCAP_Human1.06089899
102PIAS1_25552417_ChIP-Seq_VCAP_Human1.04944865
103SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04456050
104MYC_18940864_ChIP-ChIP_HL60_Human1.04305243
105STAT3_23295773_ChIP-Seq_U87_Human1.03949681
106GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02988334
107EZH2_27294783_Chip-Seq_NPCs_Mouse1.02701444
108GBX2_23144817_ChIP-Seq_PC3_Human1.02130598
109SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02083256
110ELK1_22589737_ChIP-Seq_MCF10A_Human1.00814654
111SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99500645
112TAF15_26573619_Chip-Seq_HEK293_Human0.98973631
113RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97147785
114SMAD3_21741376_ChIP-Seq_EPCs_Human0.95742559
115SOX2_19829295_ChIP-Seq_ESCs_Human0.95022485
116NANOG_19829295_ChIP-Seq_ESCs_Human0.95022485
117* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.94924425
118RUNX2_22187159_ChIP-Seq_PCA_Human0.94828339
119TCF4_23295773_ChIP-Seq_U87_Human0.94376059
120TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94059557
121POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94059557
122BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93775338
123NFE2_27457419_Chip-Seq_LIVER_Mouse0.93553804
124SPI1_23547873_ChIP-Seq_NB4_Human0.92519252
125KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91798776
126TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91283226
127PCGF2_27294783_Chip-Seq_NPCs_Mouse0.91279549
128NANOG_18555785_ChIP-Seq_MESCs_Mouse0.91224528
129FOXA1_25329375_ChIP-Seq_VCAP_Human0.90993866
130FOXA1_27270436_Chip-Seq_PROSTATE_Human0.90993866
131E2F1_21310950_ChIP-Seq_MCF-7_Human0.89762130
132POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87959996
133ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87023181
134NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.85749798
135KDM5A_27292631_Chip-Seq_BREAST_Human0.83853059
136ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81811263
137SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81486314
138SOX9_26525672_Chip-Seq_HEART_Mouse0.81248558
139SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.79071145
140CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.78641269
141FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78562054
142ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.77339148
143RNF2_27304074_Chip-Seq_NSC_Mouse0.75576205
144FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.74990317
145E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.74734708
146SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70917390
147NANOG_16153702_ChIP-ChIP_HESCs_Human0.70071056
148BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.68430365
149ER_23166858_ChIP-Seq_MCF-7_Human0.67406147

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy2.75064043
2MP0006292_abnormal_olfactory_placode2.70245350
3MP0008789_abnormal_olfactory_epithelium2.68495154
4MP0003718_maternal_effect2.65573076
5MP0003880_abnormal_central_pattern2.60521710
6MP0008057_abnormal_DNA_replication2.58080846
7MP0001529_abnormal_vocalization2.55242342
8MP0008995_early_reproductive_senescence2.46480337
9MP0008058_abnormal_DNA_repair2.37686899
10MP0005499_abnormal_olfactory_system2.30882530
11MP0005394_taste/olfaction_phenotype2.30882530
12MP0010094_abnormal_chromosome_stability2.27053668
13MP0003890_abnormal_embryonic-extraembry1.96311013
14MP0001905_abnormal_dopamine_level1.95634052
15MP0000778_abnormal_nervous_system1.93422434
16MP0008007_abnormal_cellular_replicative1.92275078
17MP0001984_abnormal_olfaction1.90193901
18MP0003693_abnormal_embryo_hatching1.88184644
19MP0010386_abnormal_urinary_bladder1.87039735
20MP0002163_abnormal_gland_morphology1.86832738
21MP0003077_abnormal_cell_cycle1.79732235
22MP0001986_abnormal_taste_sensitivity1.78621708
23MP0005551_abnormal_eye_electrophysiolog1.71301090
24MP0004957_abnormal_blastocyst_morpholog1.67097489
25MP0003787_abnormal_imprinting1.65120850
26MP0002735_abnormal_chemical_nociception1.64382194
27MP0000015_abnormal_ear_pigmentation1.64011441
28MP0002751_abnormal_autonomic_nervous1.61259045
29MP0003763_abnormal_thymus_physiology1.60249597
30MP0002653_abnormal_ependyma_morphology1.59011238
31MP0005084_abnormal_gallbladder_morpholo1.58713221
32MP0002638_abnormal_pupillary_reflex1.57182614
33MP0003011_delayed_dark_adaptation1.56105120
34MP0004133_heterotaxia1.54384687
35MP0001188_hyperpigmentation1.53678359
36MP0002938_white_spotting1.53572975
37MP0006276_abnormal_autonomic_nervous1.50146719
38MP0002736_abnormal_nociception_after1.49087814
39MP0001968_abnormal_touch/_nociception1.48963565
40MP0004147_increased_porphyrin_level1.47538051
41MP0009697_abnormal_copulation1.47498723
42MP0001485_abnormal_pinna_reflex1.45067821
43MP0003111_abnormal_nucleus_morphology1.42780925
44MP0008877_abnormal_DNA_methylation1.41927740
45MP0001293_anophthalmia1.41431760
46MP0005423_abnormal_somatic_nervous1.39126856
47MP0002234_abnormal_pharynx_morphology1.37913054
48MP0009379_abnormal_foot_pigmentation1.37248705
49MP0002572_abnormal_emotion/affect_behav1.31611084
50MP0000566_synostosis1.31452892
51MP0006072_abnormal_retinal_apoptosis1.26749782
52MP0005645_abnormal_hypothalamus_physiol1.26042059
53MP0006035_abnormal_mitochondrial_morpho1.23506199
54MP0009046_muscle_twitch1.23069329
55MP0005379_endocrine/exocrine_gland_phen1.22253626
56MP0003121_genomic_imprinting1.21870262
57MP0001835_abnormal_antigen_presentation1.20856614
58MP0002184_abnormal_innervation1.20655483
59MP0000631_abnormal_neuroendocrine_gland1.20273864
60MP0001929_abnormal_gametogenesis1.19675095
61MP0003195_calcinosis1.19462187
62MP0002063_abnormal_learning/memory/cond1.19084211
63MP0003635_abnormal_synaptic_transmissio1.18802842
64MP0003136_yellow_coat_color1.18293272
65MP0000049_abnormal_middle_ear1.16974924
66MP0002734_abnormal_mechanical_nocicepti1.16702956
67MP0000372_irregular_coat_pigmentation1.11849789
68MP0008932_abnormal_embryonic_tissue1.11509439
69MP0005187_abnormal_penis_morphology1.09436774
70MP0009745_abnormal_behavioral_response1.08916723
71MP0003786_premature_aging1.08912073
72MP0005409_darkened_coat_color1.08683940
73MP0002272_abnormal_nervous_system1.08291971
74MP0005367_renal/urinary_system_phenotyp1.07808441
75MP0000516_abnormal_urinary_system1.07808441
76MP0000427_abnormal_hair_cycle1.07709663
77MP0003119_abnormal_digestive_system1.07365367
78MP0002557_abnormal_social/conspecific_i1.07217450
79MP0000569_abnormal_digit_pigmentation1.06985565
80MP0002210_abnormal_sex_determination1.06892586
81MP0000383_abnormal_hair_follicle1.06539845
82MP0002095_abnormal_skin_pigmentation1.06360310
83MP0004142_abnormal_muscle_tone1.06082859
84MP0004885_abnormal_endolymph1.05622967
85MP0005253_abnormal_eye_physiology1.05332349
86MP0002064_seizures1.05082358
87MP0002233_abnormal_nose_morphology1.04785669
88MP0003698_abnormal_male_reproductive1.03094507
89MP0004742_abnormal_vestibular_system1.02722388
90MP0000026_abnormal_inner_ear1.00902220
91MP0001963_abnormal_hearing_physiology1.00260146
92MP0000653_abnormal_sex_gland1.00253384
93MP0005075_abnormal_melanosome_morpholog1.00125613
94MP0004134_abnormal_chest_morphology0.98790365
95MP0002928_abnormal_bile_duct0.98566974
96MP0002102_abnormal_ear_morphology0.98529717
97MP0000647_abnormal_sebaceous_gland0.97854630
98MP0001486_abnormal_startle_reflex0.97680006
99MP0003937_abnormal_limbs/digits/tail_de0.95728881
100MP0005391_vision/eye_phenotype0.94961019
101MP0006036_abnormal_mitochondrial_physio0.93619137
102MP0004043_abnormal_pH_regulation0.93448766
103MP0000013_abnormal_adipose_tissue0.93433007
104MP0002398_abnormal_bone_marrow0.93306632
105MP0001145_abnormal_male_reproductive0.93265284
106MP0004215_abnormal_myocardial_fiber0.92011840
107MP0005671_abnormal_response_to0.91222682
108MP0005646_abnormal_pituitary_gland0.89774897
109MP0002067_abnormal_sensory_capabilities0.89478029
110MP0001324_abnormal_eye_pigmentation0.87955561
111MP0000703_abnormal_thymus_morphology0.87948166
112MP0002882_abnormal_neuron_morphology0.87677051
113MP0003861_abnormal_nervous_system0.86964511
114MP0002160_abnormal_reproductive_system0.86153184
115MP0005195_abnormal_posterior_eye0.86107320
116MP0002152_abnormal_brain_morphology0.84821210
117MP0001970_abnormal_pain_threshold0.84386570
118MP0002090_abnormal_vision0.83922702
119MP0002420_abnormal_adaptive_immunity0.83251096
120MP0003315_abnormal_perineum_morphology0.82539192
121MP0004859_abnormal_synaptic_plasticity0.82394963
122MP0001819_abnormal_immune_cell0.82023218
123MP0002752_abnormal_somatic_nervous0.81545501
124MP0001286_abnormal_eye_development0.81511659
125MP0004270_analgesia0.81203643
126MP0010030_abnormal_orbit_morphology0.81199708
127MP0000465_gastrointestinal_hemorrhage0.80827384
128MP0000537_abnormal_urethra_morphology0.80810264
129MP0000681_abnormal_thyroid_gland0.80699463
130MP0005386_behavior/neurological_phenoty0.80664231
131MP0004924_abnormal_behavior0.80664231
132MP0005395_other_phenotype0.80638359
133MP0005171_absent_coat_pigmentation0.79997994
134MP0002277_abnormal_respiratory_mucosa0.79774489
135MP0000313_abnormal_cell_death0.79485349
136MP0004811_abnormal_neuron_physiology0.78280482
137MP0000716_abnormal_immune_system0.76870647
138MP0005389_reproductive_system_phenotype0.76445960
139MP0002733_abnormal_thermal_nociception0.76400245
140MP0003122_maternal_imprinting0.75921674
141MP0003567_abnormal_fetal_cardiomyocyte0.74581869

Predicted human phenotypes

RankGene SetZ-score
1Medial flaring of the eyebrow (HP:0010747)3.23054219
2Acute necrotizing encephalopathy (HP:0006965)3.22746694
3Abnormal hair whorl (HP:0010721)3.19825615
4Nephrogenic diabetes insipidus (HP:0009806)3.09514868
5Gait imbalance (HP:0002141)3.05770348
6Congenital primary aphakia (HP:0007707)2.95195825
7Renal cortical cysts (HP:0000803)2.93732884
8Abnormal ciliary motility (HP:0012262)2.88775959
9Methylmalonic acidemia (HP:0002912)2.88261343
10Abnormal mitochondria in muscle tissue (HP:0008316)2.88119601
11Aplastic anemia (HP:0001915)2.84741454
12Abnormal respiratory epithelium morphology (HP:0012253)2.83915026
13Abnormal respiratory motile cilium morphology (HP:0005938)2.83915026
14Abnormality of cochlea (HP:0000375)2.83119938
15Tubulointerstitial nephritis (HP:0001970)2.79038129
16Abnormal respiratory motile cilium physiology (HP:0012261)2.73282435
17Retinal dysplasia (HP:0007973)2.71090169
18Mitochondrial inheritance (HP:0001427)2.68532780
19Abnormality of the renal medulla (HP:0100957)2.60604581
20Aplasia/Hypoplasia of the tongue (HP:0010295)2.60091955
21Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.60013418
22Morphological abnormality of the inner ear (HP:0011390)2.59236743
23Hypothermia (HP:0002045)2.58050832
24Rhinitis (HP:0012384)2.57090628
253-Methylglutaconic aciduria (HP:0003535)2.57054821
26Pancreatic fibrosis (HP:0100732)2.54307263
27Genital tract atresia (HP:0001827)2.53705359
28Progressive macrocephaly (HP:0004481)2.51564752
29True hermaphroditism (HP:0010459)2.50762089
30Abnormality of the labia minora (HP:0012880)2.48990672
31Abnormality of the renal cortex (HP:0011035)2.48589047
3211 pairs of ribs (HP:0000878)2.46510418
33Abnormal biliary tract physiology (HP:0012439)2.45100652
34Bile duct proliferation (HP:0001408)2.45100652
35Vaginal atresia (HP:0000148)2.45027877
36Cerebral hypomyelination (HP:0006808)2.40881163
37Chronic hepatic failure (HP:0100626)2.38548612
38Dynein arm defect of respiratory motile cilia (HP:0012255)2.35260300
39Absent/shortened dynein arms (HP:0200106)2.35260300
40Aplasia/Hypoplasia of the tibia (HP:0005772)2.34656401
41Colon cancer (HP:0003003)2.34435333
42Supernumerary spleens (HP:0009799)2.31471656
43Type I transferrin isoform profile (HP:0003642)2.31392689
44Cystic liver disease (HP:0006706)2.29487730
45Methylmalonic aciduria (HP:0012120)2.28996728
46Increased CSF lactate (HP:0002490)2.28494495
47Median cleft lip (HP:0000161)2.24491562
48Type II lissencephaly (HP:0007260)2.22741628
49Occipital encephalocele (HP:0002085)2.21729828
50Agnosia (HP:0010524)2.20563880
51Increased hepatocellular lipid droplets (HP:0006565)2.19735162
52Acute encephalopathy (HP:0006846)2.19521832
53Reticulocytopenia (HP:0001896)2.17677276
54Short tibia (HP:0005736)2.17558482
55Lipid accumulation in hepatocytes (HP:0006561)2.16775369
56Abnormal lung lobation (HP:0002101)2.15647901
57Patellar aplasia (HP:0006443)2.15229330
58Abnormality of alanine metabolism (HP:0010916)2.14300716
59Hyperalaninemia (HP:0003348)2.14300716
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.14300716
61Abolished electroretinogram (ERG) (HP:0000550)2.14010591
62Lissencephaly (HP:0001339)2.11586833
63Congenital hepatic fibrosis (HP:0002612)2.09164216
64Preaxial hand polydactyly (HP:0001177)2.08859572
65Birth length less than 3rd percentile (HP:0003561)2.08421948
66Pancreatic cysts (HP:0001737)2.07841106
67Poor coordination (HP:0002370)2.07187681
68Hepatocellular necrosis (HP:0001404)2.06591430
69Limb dystonia (HP:0002451)2.05991851
70Optic nerve coloboma (HP:0000588)2.04811888
71Hypoplasia of the capital femoral epiphysis (HP:0003090)2.04650968
72Severe visual impairment (HP:0001141)2.01237434
73Aplasia/Hypoplasia of the patella (HP:0006498)1.98291749
74Intestinal atresia (HP:0011100)1.95753626
75Parakeratosis (HP:0001036)1.95356215
76Hepatic necrosis (HP:0002605)1.94977836
77Progressive inability to walk (HP:0002505)1.94041502
78Male pseudohermaphroditism (HP:0000037)1.93000230
79IgM deficiency (HP:0002850)1.92900721
80Oculomotor apraxia (HP:0000657)1.91117583
81Protruding tongue (HP:0010808)1.90110665
82Septo-optic dysplasia (HP:0100842)1.89504841
83Bifid tongue (HP:0010297)1.88436710
84IgG deficiency (HP:0004315)1.88302766
85Optic disc pallor (HP:0000543)1.87016338
86Optic nerve hypoplasia (HP:0000609)1.86841767
87Absent epiphyses (HP:0010577)1.85324682
88Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.85324682
89Abnormal number of incisors (HP:0011064)1.84642406
90Congenital stationary night blindness (HP:0007642)1.83576873
91Abnormality of cells of the erythroid lineage (HP:0012130)1.83534765
92Gastrointestinal atresia (HP:0002589)1.83067640
93Facial cleft (HP:0002006)1.82548467
94Abnormality of the ileum (HP:0001549)1.80150867
95Degeneration of anterior horn cells (HP:0002398)1.79751794
96Abnormality of the anterior horn cell (HP:0006802)1.79751794
97Increased serum lactate (HP:0002151)1.79081596
98Abnormality of the columella (HP:0009929)1.78534615
99Postaxial foot polydactyly (HP:0001830)1.77551803
100Narrow forehead (HP:0000341)1.77514533
101Meckel diverticulum (HP:0002245)1.77465514
102Molar tooth sign on MRI (HP:0002419)1.77375370
103Abnormality of midbrain morphology (HP:0002418)1.77375370
104Hyperglycinemia (HP:0002154)1.76392679
105Septate vagina (HP:0001153)1.74830577
106Leukodystrophy (HP:0002415)1.74623567
107Postaxial hand polydactyly (HP:0001162)1.73773439
108Broad foot (HP:0001769)1.73481040
109Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.73448427
110Optic neuritis (HP:0100653)1.73369726
111Retrobulbar optic neuritis (HP:0100654)1.73369726
112Aplasia/Hypoplasia of the lens (HP:0008063)1.73368815
113Renal Fanconi syndrome (HP:0001994)1.72515595
114Sloping forehead (HP:0000340)1.71054990
115Thyroid-stimulating hormone excess (HP:0002925)1.70727058
116Dandy-Walker malformation (HP:0001305)1.70084517
117Aplasia/Hypoplasia of the uvula (HP:0010293)1.69233190
118Cerebral edema (HP:0002181)1.68763062
119Abnormality of glycolysis (HP:0004366)1.67995288
120Increased serum pyruvate (HP:0003542)1.67995288
121Prominent nasal bridge (HP:0000426)1.67051822
122Inability to walk (HP:0002540)1.66078473
123Lactic acidosis (HP:0003128)1.65628911
124Abnormal protein glycosylation (HP:0012346)1.64573256
125Abnormal glycosylation (HP:0012345)1.64573256
126Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.64573256
127Abnormal protein N-linked glycosylation (HP:0012347)1.64573256
128Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.62648910
129Decreased testicular size (HP:0008734)1.62560040
130Decreased activity of mitochondrial respiratory chain (HP:0008972)1.62098036
131Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.62098036
132Pendular nystagmus (HP:0012043)1.59907284
133Tented upper lip vermilion (HP:0010804)1.59520143
134Abnormal number of erythroid precursors (HP:0012131)1.57851265
135Heterochromia iridis (HP:0001100)1.57153262
136Cellular immunodeficiency (HP:0005374)1.56969042
137Sclerocornea (HP:0000647)1.56753512
138Recurrent pneumonia (HP:0006532)1.56396397
139Medulloblastoma (HP:0002885)1.56136996
140Atrophy/Degeneration involving motor neurons (HP:0007373)1.55676497
141Multicystic kidney dysplasia (HP:0000003)1.54789963
142Hypoplastic pelvis (HP:0008839)1.54246262
143Anencephaly (HP:0002323)1.53544261
144Adrenal hypoplasia (HP:0000835)1.53103097
145Nephronophthisis (HP:0000090)1.51311896
146Lymphoma (HP:0002665)1.50347302
147Specific learning disability (HP:0001328)1.49864058
148Aganglionic megacolon (HP:0002251)1.49095733
149Increased IgM level (HP:0003496)1.48410198
150Chronic sinusitis (HP:0011109)1.47770802
151Abnormality of the intervertebral disk (HP:0005108)1.47012599
152Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.45914504
153Bone marrow hypocellularity (HP:0005528)1.45329010
154Rough bone trabeculation (HP:0100670)1.45074377

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIM282.93758375
2ZAK2.90617043
3WNK32.71383626
4BUB12.66566322
5SRPK12.58292555
6MAP4K22.51618441
7MAP2K72.50189061
8FRK2.40611045
9VRK12.37301305
10CASK2.36582502
11NUAK12.34743210
12MAPK132.33098319
13MAP3K122.30406502
14PNCK2.26818674
15BCKDK2.19037412
16EIF2AK32.10665706
17MKNK12.06253432
18TSSK62.04900903
19STK162.04343477
20DYRK21.93542827
21PASK1.89566321
22MARK11.86125213
23EIF2AK11.81505166
24EPHA31.79406279
25ARAF1.77948284
26BMPR1B1.73392550
27LIMK11.72548808
28YES11.67589714
29TXK1.66697077
30TESK21.65996470
31BCR1.58441599
32PLK31.57859052
33MST41.56540180
34UHMK11.56266088
35PLK21.55222393
36CCNB11.50436082
37PINK11.49706740
38EPHA41.48387300
39DAPK11.46241421
40MKNK21.41943128
41PRPF4B1.40070459
42EIF2AK21.39878221
43SIK31.39478435
44WEE11.38585008
45GRK11.34135242
46TNIK1.32012727
47TGFBR11.29555518
48PIM21.22087207
49TAOK31.16462303
50CSNK1G31.15671487
51DYRK31.13740429
52CDK191.09826707
53MAP3K41.00973864
54TTK0.98619532
55GRK60.98444581
56BRAF0.95396037
57NTRK30.95298445
58VRK20.93240552
59ACVR1B0.91491717
60ERBB30.91338226
61PLK40.91123286
62SYK0.90253099
63CDC70.89096563
64BMPR20.87206183
65IRAK40.86684749
66STK38L0.84390365
67ATR0.83623176
68KSR10.82990126
69CLK10.82974048
70FES0.82627839
71NEK10.82437590
72RAF10.81981310
73SGK20.80537558
74MAP4K10.78926436
75PAK30.78296934
76CDK80.77093506
77INSRR0.75776353
78PRKCE0.75541631
79ADRBK20.74784574
80DYRK1A0.73559014
81BRD40.73455414
82BTK0.72913614
83SGK2230.72347018
84SGK4940.72347018
85MYLK0.71194871
86PRKCG0.71064418
87CSNK1G10.69737584
88AURKA0.68387494
89NME10.67444388
90CHEK20.66797724
91LMTK20.64044025
92RPS6KA50.64024692
93* ATM0.63475417
94TEC0.62654446
95CSNK1G20.61314773
96RPS6KA20.60783475
97RPS6KA60.60757412
98LYN0.58308101
99RPS6KL10.57162361
100RPS6KC10.57162361
101CSNK2A10.53625735
102NTRK20.52273644
103CAMK2B0.51296533
104STK30.51225178
105TLK10.51204075
106CSNK1A1L0.51010766
107FER0.50652981
108TIE10.49870867
109CDK70.49691153
110CSNK1D0.48926844
111SIK20.48921117
112ITK0.48877141
113RPS6KB10.47763155
114PRKCI0.47718442
115PLK10.46639546
116RPS6KA40.46244339
117MAP2K40.46097047
118PIM10.45108397
119AURKB0.44739852
120MINK10.44573448
121CSNK1A10.44306347
122STK240.44260853
123CDK180.44233107
124BRSK20.44214864
125ROCK20.43854739
126PBK0.43657600
127CSNK2A20.43555327
128NEK20.43441216
129STK40.43105083
130OXSR10.42818891
131RPS6KB20.42522986
132MAPKAPK50.42284805
133PKN10.42173083
134AKT30.40627291
135NLK0.39490780
136LCK0.39174325
137MAPK150.37990936
138ERBB40.37054665
139CAMK2A0.36803509
140CSNK1E0.32542735
141PRKACB0.31565182
142FLT30.31244474
143ADRBK10.29877260

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.58938803
2Mismatch repair_Homo sapiens_hsa034303.14490415
3Ribosome_Homo sapiens_hsa030102.91653814
4DNA replication_Homo sapiens_hsa030302.84477280
5RNA polymerase_Homo sapiens_hsa030202.73598482
6Spliceosome_Homo sapiens_hsa030402.64487025
7Base excision repair_Homo sapiens_hsa034102.59597336
8Protein export_Homo sapiens_hsa030602.43643887
9Oxidative phosphorylation_Homo sapiens_hsa001902.34127523
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.24331897
11Nucleotide excision repair_Homo sapiens_hsa034202.13342641
12Parkinsons disease_Homo sapiens_hsa050122.04993525
13Homologous recombination_Homo sapiens_hsa034402.01027741
14Butanoate metabolism_Homo sapiens_hsa006501.99698510
15Non-homologous end-joining_Homo sapiens_hsa034501.90021841
16Propanoate metabolism_Homo sapiens_hsa006401.79924286
17Pyrimidine metabolism_Homo sapiens_hsa002401.75409970
18Basal transcription factors_Homo sapiens_hsa030221.74944412
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.74829409
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.69145567
21RNA transport_Homo sapiens_hsa030131.61123170
22Huntingtons disease_Homo sapiens_hsa050161.60239139
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.58367855
24Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.55320104
25Alzheimers disease_Homo sapiens_hsa050101.54359803
26Steroid biosynthesis_Homo sapiens_hsa001001.53737740
27RNA degradation_Homo sapiens_hsa030181.53250782
28Phototransduction_Homo sapiens_hsa047441.48372324
29Primary immunodeficiency_Homo sapiens_hsa053401.46773594
30Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.44122141
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.41826502
32mRNA surveillance pathway_Homo sapiens_hsa030151.33058364
33Peroxisome_Homo sapiens_hsa041461.31503884
34Fanconi anemia pathway_Homo sapiens_hsa034601.30915638
35Collecting duct acid secretion_Homo sapiens_hsa049661.27642240
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.27436044
37Selenocompound metabolism_Homo sapiens_hsa004501.26262739
38Vibrio cholerae infection_Homo sapiens_hsa051101.24688070
39Cell cycle_Homo sapiens_hsa041101.23816977
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.19697170
41Purine metabolism_Homo sapiens_hsa002301.18522750
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.15726471
43Epstein-Barr virus infection_Homo sapiens_hsa051691.10100071
44Nitrogen metabolism_Homo sapiens_hsa009101.08714718
45SNARE interactions in vesicular transport_Homo sapiens_hsa041301.07947303
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.03178215
47Serotonergic synapse_Homo sapiens_hsa047261.02641658
48Olfactory transduction_Homo sapiens_hsa047400.97609389
49Circadian rhythm_Homo sapiens_hsa047100.94942620
50Nicotine addiction_Homo sapiens_hsa050330.93352290
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92344613
52Primary bile acid biosynthesis_Homo sapiens_hsa001200.91701341
53Synaptic vesicle cycle_Homo sapiens_hsa047210.89777435
54One carbon pool by folate_Homo sapiens_hsa006700.87591851
55Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.87479258
56Regulation of autophagy_Homo sapiens_hsa041400.85721507
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.85161786
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.85134395
59Alcoholism_Homo sapiens_hsa050340.83667617
60Colorectal cancer_Homo sapiens_hsa052100.81336456
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80782128
62beta-Alanine metabolism_Homo sapiens_hsa004100.80675962
63Dopaminergic synapse_Homo sapiens_hsa047280.80480487
64N-Glycan biosynthesis_Homo sapiens_hsa005100.77885919
65Taste transduction_Homo sapiens_hsa047420.77752256
66Metabolic pathways_Homo sapiens_hsa011000.76268681
67Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.73679046
68Sulfur metabolism_Homo sapiens_hsa009200.71064009
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.70866194
70Phagosome_Homo sapiens_hsa041450.69595147
71Autoimmune thyroid disease_Homo sapiens_hsa053200.67834843
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.67120887
73Caffeine metabolism_Homo sapiens_hsa002320.67015021
74Allograft rejection_Homo sapiens_hsa053300.66893945
75Oocyte meiosis_Homo sapiens_hsa041140.66358075
76Amphetamine addiction_Homo sapiens_hsa050310.65734352
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64879003
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64205367
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63679999
80Tryptophan metabolism_Homo sapiens_hsa003800.62966785
81Antigen processing and presentation_Homo sapiens_hsa046120.62959807
82Cardiac muscle contraction_Homo sapiens_hsa042600.62482956
83Morphine addiction_Homo sapiens_hsa050320.62021707
84Long-term potentiation_Homo sapiens_hsa047200.59549566
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59506704
86Axon guidance_Homo sapiens_hsa043600.59377659
87Rheumatoid arthritis_Homo sapiens_hsa053230.59256097
88Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58848176
89Shigellosis_Homo sapiens_hsa051310.58265048
90Linoleic acid metabolism_Homo sapiens_hsa005910.57164547
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56458281
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55964200
93Graft-versus-host disease_Homo sapiens_hsa053320.55520155
94Pyruvate metabolism_Homo sapiens_hsa006200.55213651
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54932935
96Hedgehog signaling pathway_Homo sapiens_hsa043400.53936681
97Circadian entrainment_Homo sapiens_hsa047130.53004505
98Glutamatergic synapse_Homo sapiens_hsa047240.52480617
99Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52143483
100p53 signaling pathway_Homo sapiens_hsa041150.52012748
101T cell receptor signaling pathway_Homo sapiens_hsa046600.51903880
102Systemic lupus erythematosus_Homo sapiens_hsa053220.51761971
103Herpes simplex infection_Homo sapiens_hsa051680.50926677
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.50685590
105Glutathione metabolism_Homo sapiens_hsa004800.50201252
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50016245
107Chemical carcinogenesis_Homo sapiens_hsa052040.49418476
108Steroid hormone biosynthesis_Homo sapiens_hsa001400.49306223
109Viral myocarditis_Homo sapiens_hsa054160.48792729
110Asthma_Homo sapiens_hsa053100.48245568
111Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.48187583
112Fatty acid metabolism_Homo sapiens_hsa012120.45656569
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43570411
114Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43329479
115Viral carcinogenesis_Homo sapiens_hsa052030.43064167
116ABC transporters_Homo sapiens_hsa020100.42496444
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41158953
118TGF-beta signaling pathway_Homo sapiens_hsa043500.40247477
119Fatty acid elongation_Homo sapiens_hsa000620.39867463
120Long-term depression_Homo sapiens_hsa047300.39847953
121Measles_Homo sapiens_hsa051620.39158010
122Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39125979
123Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38724144
124Cholinergic synapse_Homo sapiens_hsa047250.38318920
125Type I diabetes mellitus_Homo sapiens_hsa049400.38155535
126Retinol metabolism_Homo sapiens_hsa008300.37942233
127Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36681115
128Folate biosynthesis_Homo sapiens_hsa007900.35983471
129B cell receptor signaling pathway_Homo sapiens_hsa046620.34169755
1302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33100607
131Basal cell carcinoma_Homo sapiens_hsa052170.32244841
132Hematopoietic cell lineage_Homo sapiens_hsa046400.32052866
133HTLV-I infection_Homo sapiens_hsa051660.31987831
134NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31692684
135GABAergic synapse_Homo sapiens_hsa047270.31110575
136Cocaine addiction_Homo sapiens_hsa050300.30464725
137Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.30442665
138Legionellosis_Homo sapiens_hsa051340.30314085
139Apoptosis_Homo sapiens_hsa042100.29593610
140Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29495316
141Fatty acid degradation_Homo sapiens_hsa000710.28599106
142NF-kappa B signaling pathway_Homo sapiens_hsa040640.26804130
143Neurotrophin signaling pathway_Homo sapiens_hsa047220.26123457
144Wnt signaling pathway_Homo sapiens_hsa043100.26046198
145Other glycan degradation_Homo sapiens_hsa005110.25653855
146Salmonella infection_Homo sapiens_hsa051320.24565302
147Ether lipid metabolism_Homo sapiens_hsa005650.23564207

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