TTC36

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene has three tetratricopeptide repeats and is a chaperone for heat shock protein 70. The encoded protein may function as a tumor suppressor in hepatocellular carcinoma (HCC) since it promotes apoptosis but is downregulated in HCC. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1omega-hydroxylase P450 pathway (GO:0097267)8.20073664
2epoxygenase P450 pathway (GO:0019373)8.13198064
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.63804679
4L-phenylalanine catabolic process (GO:0006559)7.63804679
5L-phenylalanine metabolic process (GO:0006558)7.36798359
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.36798359
7aromatic amino acid family catabolic process (GO:0009074)6.93301879
8indole-containing compound catabolic process (GO:0042436)6.29379884
9indolalkylamine catabolic process (GO:0046218)6.29379884
10tryptophan catabolic process (GO:0006569)6.29379884
11glyoxylate metabolic process (GO:0046487)6.22380576
12ethanol metabolic process (GO:0006067)6.09744897
13kynurenine metabolic process (GO:0070189)6.01258605
14triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.95880543
15tryptophan metabolic process (GO:0006568)5.93020324
16cysteine metabolic process (GO:0006534)5.77762350
17bile acid biosynthetic process (GO:0006699)5.77258125
18oxidative demethylation (GO:0070989)5.53296743
19urea metabolic process (GO:0019627)5.47513420
20urea cycle (GO:0000050)5.47513420
21sulfur amino acid catabolic process (GO:0000098)5.41098816
22serine family amino acid catabolic process (GO:0009071)5.36108237
23alpha-linolenic acid metabolic process (GO:0036109)5.26572156
24high-density lipoprotein particle remodeling (GO:0034375)5.26374514
25lysine metabolic process (GO:0006553)5.25777331
26lysine catabolic process (GO:0006554)5.25777331
27negative regulation of fibrinolysis (GO:0051918)5.25260127
28blood coagulation, intrinsic pathway (GO:0007597)5.08609400
29nitrogen cycle metabolic process (GO:0071941)5.06090824
30fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.06009683
31aromatic amino acid family metabolic process (GO:0009072)5.05952408
32protein carboxylation (GO:0018214)5.03571021
33peptidyl-glutamic acid carboxylation (GO:0017187)5.03571021
34regulation of fibrinolysis (GO:0051917)5.02409793
35homocysteine metabolic process (GO:0050667)4.96649369
36bile acid metabolic process (GO:0008206)4.89512731
37opsonization (GO:0008228)4.87070144
38complement activation, alternative pathway (GO:0006957)4.82737570
39amino-acid betaine metabolic process (GO:0006577)4.79330563
40regulation of protein activation cascade (GO:2000257)4.79096893
41very-low-density lipoprotein particle assembly (GO:0034379)4.77035272
42tyrosine metabolic process (GO:0006570)4.76980655
43alpha-amino acid catabolic process (GO:1901606)4.75781584
44regulation of cholesterol esterification (GO:0010872)4.65319383
45cellular ketone body metabolic process (GO:0046950)4.64046093
46regulation of triglyceride catabolic process (GO:0010896)4.57745374
47protein activation cascade (GO:0072376)4.57420984
48reverse cholesterol transport (GO:0043691)4.57183188
49negative regulation of lipase activity (GO:0060192)4.54079510
50drug catabolic process (GO:0042737)4.52974239
51protein-lipid complex remodeling (GO:0034368)4.49226014
52macromolecular complex remodeling (GO:0034367)4.49226014
53plasma lipoprotein particle remodeling (GO:0034369)4.49226014
54S-adenosylmethionine metabolic process (GO:0046500)4.48051290
55negative regulation of sterol transport (GO:0032372)4.46471829
56negative regulation of cholesterol transport (GO:0032375)4.46471829
57regulation of complement activation (GO:0030449)4.46391880
58indolalkylamine metabolic process (GO:0006586)4.46043622
59serine family amino acid metabolic process (GO:0009069)4.44511036
60cellular amino acid catabolic process (GO:0009063)4.43037184
61complement activation (GO:0006956)4.42514322
62protein-lipid complex assembly (GO:0065005)4.41003000
63glutamate metabolic process (GO:0006536)4.40684386
64positive regulation of fatty acid biosynthetic process (GO:0045723)4.38324695
65regulation of plasminogen activation (GO:0010755)4.38150314
66acylglycerol homeostasis (GO:0055090)4.37190465
67triglyceride homeostasis (GO:0070328)4.37190465
68cellular modified amino acid catabolic process (GO:0042219)4.35684847
69glycine metabolic process (GO:0006544)4.34328976
70cellular biogenic amine catabolic process (GO:0042402)4.34165360
71amine catabolic process (GO:0009310)4.34165360
72urate metabolic process (GO:0046415)4.32301029
73phospholipid efflux (GO:0033700)4.30799027
74drug transmembrane transport (GO:0006855)4.30607317
75coenzyme catabolic process (GO:0009109)4.29472646
76plasma lipoprotein particle organization (GO:0071827)4.29428965
77cellular glucuronidation (GO:0052695)4.24208847
78benzene-containing compound metabolic process (GO:0042537)4.23824209
79serine family amino acid biosynthetic process (GO:0009070)4.21959742
80complement activation, classical pathway (GO:0006958)4.16096360
81plasma lipoprotein particle clearance (GO:0034381)4.14865122
82aldehyde catabolic process (GO:0046185)4.11294927
83bile acid and bile salt transport (GO:0015721)4.10450011
84exogenous drug catabolic process (GO:0042738)4.08317768
85short-chain fatty acid metabolic process (GO:0046459)4.06723551
86imidazole-containing compound metabolic process (GO:0052803)4.06467391
87phenylpropanoid metabolic process (GO:0009698)4.06382156
88dicarboxylic acid biosynthetic process (GO:0043650)4.04315465
89protein-lipid complex subunit organization (GO:0071825)4.03515562
90ketone body metabolic process (GO:1902224)4.01658533
91arginine metabolic process (GO:0006525)4.00938755
92ethanol oxidation (GO:0006069)3.99761292
93acute-phase response (GO:0006953)3.98079282
94positive regulation of lipid catabolic process (GO:0050996)3.94759393
95cytolysis (GO:0019835)3.92079104
96cholesterol efflux (GO:0033344)3.90329192
97negative regulation of hemostasis (GO:1900047)3.89137885
98negative regulation of blood coagulation (GO:0030195)3.89137885
99organic acid catabolic process (GO:0016054)3.88549459
100carboxylic acid catabolic process (GO:0046395)3.88549459
101aspartate family amino acid catabolic process (GO:0009068)3.86701589
102cellular response to zinc ion (GO:0071294)3.86571747
103uronic acid metabolic process (GO:0006063)3.84422067
104glucuronate metabolic process (GO:0019585)3.84422067
105acetyl-CoA metabolic process (GO:0006084)3.83992837
106regulation of humoral immune response (GO:0002920)3.83482332
107negative regulation of fatty acid biosynthetic process (GO:0045717)3.77521884
108fibrinolysis (GO:0042730)3.76967027
109plasma lipoprotein particle assembly (GO:0034377)3.74847886
110disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.74497827
111killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.74497827
1122-oxoglutarate metabolic process (GO:0006103)3.70251418
113low-density lipoprotein particle remodeling (GO:0034374)3.69344458
114flavonoid metabolic process (GO:0009812)3.68357486
115regulation of lipoprotein particle clearance (GO:0010984)3.65969397
116cofactor catabolic process (GO:0051187)3.65943241
117regulation of bile acid biosynthetic process (GO:0070857)3.65541108
118positive regulation of lipoprotein lipase activity (GO:0051006)3.62011459
119positive regulation of triglyceride lipase activity (GO:0061365)3.62011459
120regulation of cholesterol homeostasis (GO:2000188)3.61845379
121drug transport (GO:0015893)3.60024920
122alkaloid metabolic process (GO:0009820)3.59769966
123cholesterol homeostasis (GO:0042632)3.59465030
124drug metabolic process (GO:0017144)3.58075335
125fatty acid oxidation (GO:0019395)3.57398329
126monocarboxylic acid catabolic process (GO:0072329)3.57267420
127carnitine metabolic process (GO:0009437)3.56836356
128positive regulation of triglyceride metabolic process (GO:0090208)3.56661366
129fatty acid beta-oxidation (GO:0006635)3.56374306
130NAD biosynthetic process (GO:0009435)3.55722142
131sterol homeostasis (GO:0055092)3.55542425
132negative regulation of coagulation (GO:0050819)3.53221276
133regulation of fatty acid biosynthetic process (GO:0042304)3.51981230
134regulation of lipoprotein metabolic process (GO:0050746)3.47718880
135regulation of triglyceride metabolic process (GO:0090207)3.44352904
136negative regulation of wound healing (GO:0061045)3.41108850
137regulation of cholesterol transport (GO:0032374)3.36242943
138regulation of sterol transport (GO:0032371)3.36242943

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.37546370
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.16556024
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.74009314
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.42290287
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.16506082
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.03157372
7* CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.86518355
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.93754529
9* CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.82605593
10STAT6_21828071_ChIP-Seq_BEAS2B_Human3.18846857
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.17233982
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.13703151
13TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.13110430
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8497222
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.82629302
16* ELF1_20517297_ChIP-Seq_JURKAT_Human1.69996691
17FOXA2_19822575_ChIP-Seq_HepG2_Human1.60749415
18CLOCK_20551151_ChIP-Seq_293T_Human1.59660181
19CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.56463241
20* SRY_22984422_ChIP-ChIP_TESTIS_Rat1.52503073
21DNAJC2_21179169_ChIP-ChIP_NT2_Human1.48394463
22P68_20966046_ChIP-Seq_HELA_Human1.48215720
23HNF4A_19822575_ChIP-Seq_HepG2_Human1.46221058
24CTCF_27219007_Chip-Seq_Bcells_Human1.40779820
25TET1_21451524_ChIP-Seq_MESCs_Mouse1.39960894
26HTT_18923047_ChIP-ChIP_STHdh_Human1.35965097
27* E2F1_20622854_ChIP-Seq_HELA_Human1.32562035
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.30246582
29TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29371409
30GATA1_22025678_ChIP-Seq_K562_Human1.29219827
31STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.23666742
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22125103
33CTCF_20526341_ChIP-Seq_ESCs_Human1.22071639
34BCL6_27268052_Chip-Seq_Bcells_Human1.19783902
35RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17918564
36* RAC3_21632823_ChIP-Seq_H3396_Human1.17776023
37P300_27268052_Chip-Seq_Bcells_Human1.16278515
38* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.14473822
39* PHF8_20622854_ChIP-Seq_HELA_Human1.12520683
40ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.11805766
41SMC4_20622854_ChIP-Seq_HELA_Human1.11181088
42BCOR_27268052_Chip-Seq_Bcells_Human1.07338292
43TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.06856781
44IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.05724464
45RARG_19884340_ChIP-ChIP_MEFs_Mouse1.04197433
46PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03856483
47ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.01486309
48JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.00653888
49SOX2_27498859_Chip-Seq_STOMACH_Mouse0.98593504
50ERA_21632823_ChIP-Seq_H3396_Human0.97050468
51* SOX2_21211035_ChIP-Seq_LN229_Human0.96960940
52ESR1_15608294_ChIP-ChIP_MCF-7_Human0.96463887
53YY1_22570637_ChIP-Seq_MALME-3M_Human0.95096307
54NANOG_20526341_ChIP-Seq_ESCs_Human0.94651495
55SPI1_20517297_ChIP-Seq_HL60_Human0.93662473
56SA1_27219007_Chip-Seq_Bcells_Human0.91741765
57RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.91536478
58CTCF_21964334_Chip-Seq_Bcells_Human0.91347407
59SA1_27219007_Chip-Seq_ERYTHROID_Human0.89212231
60PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.88159573
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.88044325
62GATA4_25053715_ChIP-Seq_YYC3_Human0.87680101
63IRF8_22096565_ChIP-ChIP_GC-B_Human0.84439932
64LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.84118148
65AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82149165
66MYC_19829295_ChIP-Seq_ESCs_Human0.81069990
67TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80499047
68CTCF_21964334_ChIP-Seq_BJAB-B_Human0.79361002
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.77981902
70SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.77883307
71ESR2_21235772_ChIP-Seq_MCF-7_Human0.77612450
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.77591147
73KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77391919
74BP1_19119308_ChIP-ChIP_Hs578T_Human0.76245576
75NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.74943017
76BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74881780
77SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.73740042
78OCT4_20526341_ChIP-Seq_ESCs_Human0.73723437
79MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.72590964
80SOX2_22085726_ChIP-Seq_NPCs_Mouse0.72247641
81RARA_24833708_ChIP-Seq_LIVER_Mouse0.72100425
82RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.71258115
83ESR1_21235772_ChIP-Seq_MCF-7_Human0.70831852
84ZNF263_19887448_ChIP-Seq_K562_Human0.70524588
85LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.70123462
86CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.68931095
87Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.68759953
88AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.68698030
89NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.68639635
90BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.68311323
91RAD21_21589869_ChIP-Seq_MESCs_Mouse0.68186552
92LXR_22292898_ChIP-Seq_THP-1_Human0.67096425
93OCT4_19829295_ChIP-Seq_ESCs_Human0.66152105
94SALL4_18804426_ChIP-ChIP_XEN_Mouse0.64810304
95BCAT_22108803_ChIP-Seq_LS180_Human0.64589423
96STAT3_1855785_ChIP-Seq_MESCs_Mouse0.63484690
97EGR1_19032775_ChIP-ChIP_M12_Human0.62834262
98FOXP1_21924763_ChIP-Seq_HESCs_Human0.62631131
99VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.61284233
100CTCF_27219007_Chip-Seq_ERYTHROID_Human0.60729562
101RARB_24833708_ChIP-Seq_LIVER_Mouse0.60494633
102CDX2_20551321_ChIP-Seq_CACO-2_Human0.59393292
103* CEBPB_22108803_ChIP-Seq_LS180_Human0.57221968
104* NRF2_20460467_ChIP-Seq_MEFs_Mouse0.57119254
105* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.57119254
106MYC_19915707_ChIP-ChIP_AK7_Human0.56365455
107AR_20517297_ChIP-Seq_VCAP_Human0.55972060
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.54126079
109FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.52590323
110ESET_19884257_ChIP-Seq_ESCs_Mouse0.51069427
111FOXA1_25552417_ChIP-Seq_VCAP_Human0.50456868
112E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.49495419
113STAT1_17558387_ChIP-Seq_HELA_Human0.48040733
114TAF2_19829295_ChIP-Seq_ESCs_Human0.47792872
115PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.46414957
116GATA6_25053715_ChIP-Seq_YYC3_Human0.46003310
117* CBP_21632823_ChIP-Seq_H3396_Human0.45840791
118P53_21459846_ChIP-Seq_SAOS-2_Human0.45748017
119FOXO3_23340844_ChIP-Seq_DLD1_Human0.45674942
120GATA1_19941827_ChIP-Seq_MEL_Mouse0.45105464
121ERG_21242973_ChIP-ChIP_JURKAT_Human0.45054105
122PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.44920705
123* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.44433357
124FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.44399082
125NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.44038176
126FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.43609656
127FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.42034891
128GATA1_19941826_ChIP-Seq_K562_Human0.41982832
129GATA2_19941826_ChIP-Seq_K562_Human0.41773781
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41710022
131PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.41013505
132PPAR_26484153_Chip-Seq_NCI-H1993_Human0.40940495
133STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.40426381
134CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.39512814
135P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.38143786
136GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.38005490
137GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.37933592
138MYC_27129775_Chip-Seq_CORNEA_Mouse0.37503901
139FOXH1_21741376_ChIP-Seq_EPCs_Human0.36922423
140GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.36763282
141EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.36486604
142RACK7_27058665_Chip-Seq_MCF-7_Human0.36380990
143EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.36185982
144LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.36182235
145NCOR_22424771_ChIP-Seq_293T_Human0.36162985

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.28289549
2MP0005360_urolithiasis7.88467779
3MP0005085_abnormal_gallbladder_physiolo6.15511900
4MP0005365_abnormal_bile_salt5.95956385
5MP0008875_abnormal_xenobiotic_pharmacok5.13284239
6MP0003806_abnormal_nucleotide_metabolis4.06043153
7MP0003252_abnormal_bile_duct3.81793506
8MP0010329_abnormal_lipoprotein_level3.37920396
9MP0005332_abnormal_amino_acid3.20824931
10MP0003195_calcinosis3.09063204
11MP0009840_abnormal_foam_cell3.08259905
12MP0005083_abnormal_biliary_tract2.80756839
13MP0004019_abnormal_vitamin_homeostasis2.59878330
14MP0001666_abnormal_nutrient_absorption2.49941411
15MP0003191_abnormal_cellular_cholesterol2.35756057
16MP0002138_abnormal_hepatobiliary_system2.29840525
17MP0000609_abnormal_liver_physiology2.05811193
18MP0002118_abnormal_lipid_homeostasis2.03724084
19MP0005319_abnormal_enzyme/_coenzyme1.86050830
20MP0003868_abnormal_feces_composition1.74420502
21MP0001764_abnormal_homeostasis1.71582426
22MP0005584_abnormal_enzyme/coenzyme_acti1.64998009
23MP0009643_abnormal_urine_homeostasis1.64448237
24MP0005451_abnormal_body_composition1.54865325
25MP0002132_abnormal_respiratory_system1.43456502
26MP0003186_abnormal_redox_activity1.41692582
27MP0005397_hematopoietic_system_phenotyp1.40038755
28MP0001545_abnormal_hematopoietic_system1.40038755
29MP0009697_abnormal_copulation1.33543127
30MP0005636_abnormal_mineral_homeostasis1.26161586
31MP0003011_delayed_dark_adaptation1.22485395
32MP0000598_abnormal_liver_morphology1.14369060
33MP0003656_abnormal_erythrocyte_physiolo1.13902722
34MP0002249_abnormal_larynx_morphology1.09579995
35MP0003705_abnormal_hypodermis_morpholog1.05228523
36MP0009764_decreased_sensitivity_to1.05184333
37MP0000604_amyloidosis1.02816802
38MP0005647_abnormal_sex_gland1.02703012
39MP0001756_abnormal_urination0.94186386
40MP0006036_abnormal_mitochondrial_physio0.93542783
41MP0009763_increased_sensitivity_to0.93198349
42MP0009278_abnormal_bone_marrow0.92526649
43MP0002876_abnormal_thyroid_physiology0.90780603
44MP0009642_abnormal_blood_homeostasis0.90213106
45MP0008469_abnormal_protein_level0.89098803
46MP0005084_abnormal_gallbladder_morpholo0.88579467
47MP0004043_abnormal_pH_regulation0.88274567
48MP0005670_abnormal_white_adipose0.85900265
49MP0002282_abnormal_trachea_morphology0.85488060
50MP0002254_reproductive_system_inflammat0.84956170
51MP0005408_hypopigmentation0.83584873
52MP0002136_abnormal_kidney_physiology0.78578108
53MP0010368_abnormal_lymphatic_system0.78186087
54MP0005376_homeostasis/metabolism_phenot0.77409473
55MP0002078_abnormal_glucose_homeostasis0.76880361
56MP0004233_abnormal_muscle_weight0.76167395
57MP0001986_abnormal_taste_sensitivity0.74989157
58MP0009765_abnormal_xenobiotic_induced0.74752408
59MP0005535_abnormal_body_temperature0.74436785
60MP0003879_abnormal_hair_cell0.73666254
61MP0005377_hearing/vestibular/ear_phenot0.73019363
62MP0003878_abnormal_ear_physiology0.73019363
63MP0005220_abnormal_exocrine_pancreas0.70870600
64MP0001661_extended_life_span0.68780294
65MP0002971_abnormal_brown_adipose0.68176743
66MP0005187_abnormal_penis_morphology0.67803441
67MP0003329_amyloid_beta_deposits0.64539781
68MP0001881_abnormal_mammary_gland0.63903001
69MP0005334_abnormal_fat_pad0.62681713
70MP0003690_abnormal_glial_cell0.61295369
71MP0005266_abnormal_metabolism0.61147302
72MP0001765_abnormal_ion_homeostasis0.60547800
73MP0009053_abnormal_anal_canal0.59142946
74MP0004130_abnormal_muscle_cell0.59034105
75MP0004270_analgesia0.58656529
76MP0006035_abnormal_mitochondrial_morpho0.57750177
77MP0002332_abnormal_exercise_endurance0.57483647
78MP0002928_abnormal_bile_duct0.55259272
79MP0003638_abnormal_response/metabolism_0.53016473
80MP0005395_other_phenotype0.51697058
81MP0005058_abnormal_lysosome_morphology0.49925811
82MP0000639_abnormal_adrenal_gland0.49786649
83MP0005646_abnormal_pituitary_gland0.49199524
84MP0006292_abnormal_olfactory_placode0.46818062
85MP0005448_abnormal_energy_balance0.46743014
86MP0005666_abnormal_adipose_tissue0.45843100
87MP0002822_catalepsy0.44361452
88MP0008874_decreased_physiological_sensi0.44326721
89MP0005464_abnormal_platelet_physiology0.43621360
90MP0000230_abnormal_systemic_arterial0.43283100
91MP0003953_abnormal_hormone_level0.42822547
92MP0008873_increased_physiological_sensi0.41870490
93MP0004782_abnormal_surfactant_physiolog0.41700681
94MP0002168_other_aberrant_phenotype0.41460586
95MP0003724_increased_susceptibility_to0.41080983
96MP0002234_abnormal_pharynx_morphology0.41075670
97MP0003075_altered_response_to0.40852333
98MP0005409_darkened_coat_color0.40749462
99MP0003718_maternal_effect0.40326630
100MP0000678_abnormal_parathyroid_gland0.39380200
101MP0008872_abnormal_physiological_respon0.39361276
102MP0009672_abnormal_birth_weight0.39113121
103MP0002069_abnormal_eating/drinking_beha0.38269357
104MP0002837_dystrophic_cardiac_calcinosis0.37649193
105MP0002796_impaired_skin_barrier0.37587044
106MP0001905_abnormal_dopamine_level0.37103830
107MP0005166_decreased_susceptibility_to0.36847911
108MP0000538_abnormal_urinary_bladder0.34682630
109MP0005595_abnormal_vascular_smooth0.34039335
110MP0002135_abnormal_kidney_morphology0.33909293
111MP0000566_synostosis0.32869511
112MP0005330_cardiomyopathy0.32858164
113MP0002269_muscular_atrophy0.32831819
114MP0003436_decreased_susceptibility_to0.32792156
115MP0000516_abnormal_urinary_system0.31929713
116MP0005367_renal/urinary_system_phenotyp0.31929713
117MP0005375_adipose_tissue_phenotype0.31482222
118MP0009115_abnormal_fat_cell0.30478883
119MP0001915_intracranial_hemorrhage0.30164197
120MP0006082_CNS_inflammation0.30058663
121MP0001845_abnormal_inflammatory_respons0.28992742
122MP0002909_abnormal_adrenal_gland0.28236038
123MP0005248_abnormal_Harderian_gland0.28125315
124MP0000249_abnormal_blood_vessel0.27395377
125MP0002970_abnormal_white_adipose0.27018905
126MP0005167_abnormal_blood-brain_barrier0.25384246
127MP0009384_cardiac_valve_regurgitation0.23413504
128MP0004883_abnormal_blood_vessel0.23280489
129MP0004264_abnormal_extraembryonic_tissu0.23180006
130MP0000579_abnormal_nail_morphology0.23157754
131MP0001243_abnormal_dermal_layer0.23112769

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.28968370
2Intrahepatic cholestasis (HP:0001406)6.77039256
3Deep venous thrombosis (HP:0002625)6.75443508
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.34692565
5Xanthomatosis (HP:0000991)6.00296071
6Prolonged partial thromboplastin time (HP:0003645)5.86482765
7Hypobetalipoproteinemia (HP:0003563)5.77690109
8Hyperlipoproteinemia (HP:0010980)5.14880526
9Abnormality of glutamine family amino acid metabolism (HP:0010902)4.73004650
10Hyperammonemia (HP:0001987)4.69120798
11Complement deficiency (HP:0004431)4.66753076
12Ketosis (HP:0001946)4.54445072
13Hyperglycinuria (HP:0003108)4.49412834
14Hyperglycinemia (HP:0002154)4.48431020
15Joint hemorrhage (HP:0005261)4.47721406
16Abnormality of aspartate family amino acid metabolism (HP:0010899)4.36524530
17Hypolipoproteinemia (HP:0010981)4.36146415
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.33619756
19Abnormality of glycine metabolism (HP:0010895)4.30123716
20Abnormality of serine family amino acid metabolism (HP:0010894)4.30123716
21Abnormality of methionine metabolism (HP:0010901)4.09085094
22Epidermoid cyst (HP:0200040)4.06871493
23Abnormality of the common coagulation pathway (HP:0010990)3.98917344
24Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.97748822
25Hypoalphalipoproteinemia (HP:0003233)3.87389775
26Fat malabsorption (HP:0002630)3.81375403
27Abnormality of pyrimidine metabolism (HP:0004353)3.77501715
28Hypoglycemic coma (HP:0001325)3.77251543
29Abnormality of fatty-acid metabolism (HP:0004359)3.61766674
30Gout (HP:0001997)3.57489967
31Abnormality of nucleobase metabolism (HP:0010932)3.47213320
32Ketoacidosis (HP:0001993)3.46044794
33Abnormality of the intrinsic pathway (HP:0010989)3.39156733
34Abnormality of complement system (HP:0005339)3.36961325
35Delayed CNS myelination (HP:0002188)3.36274658
36Abnormality of purine metabolism (HP:0004352)3.32069122
37Conjugated hyperbilirubinemia (HP:0002908)3.30905925
38Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.28480046
39Hypercholesterolemia (HP:0003124)3.24883877
40Hyperbilirubinemia (HP:0002904)3.19472637
41Abnormality of serum amino acid levels (HP:0003112)3.13142685
42Abnormality of iron homeostasis (HP:0011031)3.08037789
43Increased serum ferritin (HP:0003281)3.05013755
44Nephritis (HP:0000123)3.02071253
45Metabolic acidosis (HP:0001942)3.00370791
46Hepatocellular carcinoma (HP:0001402)2.97044126
47Microvesicular hepatic steatosis (HP:0001414)2.88512021
48Dicarboxylic aciduria (HP:0003215)2.86544865
49Abnormality of dicarboxylic acid metabolism (HP:0010995)2.86544865
50Steatorrhea (HP:0002570)2.86309418
51Vascular calcification (HP:0004934)2.86190532
52Lethargy (HP:0001254)2.80213280
53Neonatal hypoglycemia (HP:0001998)2.79782024
54Generalized aminoaciduria (HP:0002909)2.69787733
55Spontaneous abortion (HP:0005268)2.64947430
56Myocardial infarction (HP:0001658)2.62367508
57Proximal tubulopathy (HP:0000114)2.59232167
58Alkalosis (HP:0001948)2.58348889
59Hypochromic microcytic anemia (HP:0004840)2.57544134
60Cardiovascular calcification (HP:0011915)2.53657399
61Cerebral edema (HP:0002181)2.53248260
62Increased purine levels (HP:0004368)2.52287159
63Hyperuricemia (HP:0002149)2.52287159
64Systemic lupus erythematosus (HP:0002725)2.52070499
65Irritability (HP:0000737)2.51330173
66Neonatal onset (HP:0003623)2.50530085
67Spastic diplegia (HP:0001264)2.50407364
68Skin nodule (HP:0200036)2.47678400
69Malnutrition (HP:0004395)2.47083262
70Enlarged kidneys (HP:0000105)2.36053048
71Vomiting (HP:0002013)2.35978827
72Fair hair (HP:0002286)2.31691948
73Abnormality of proline metabolism (HP:0010907)2.29737935
74Hydroxyprolinuria (HP:0003080)2.29737935
75Hypoglycemic seizures (HP:0002173)2.29262580
76Mitral stenosis (HP:0001718)2.28729407
77Sensorimotor neuropathy (HP:0007141)2.27757098
78Pigmentary retinal degeneration (HP:0001146)2.26353271
79Rickets (HP:0002748)2.25227139
80Purpura (HP:0000979)2.24610925
81Late onset (HP:0003584)2.24160276
82Abnormal gallbladder morphology (HP:0012437)2.20601140
83Abnormality of urine glucose concentration (HP:0011016)2.19451949
84Glycosuria (HP:0003076)2.19451949
85Glomerulonephritis (HP:0000099)2.19067849
86Pancreatitis (HP:0001733)2.18255776
87Cholelithiasis (HP:0001081)2.16772919
88Acanthocytosis (HP:0001927)2.15963461
89Seborrheic dermatitis (HP:0001051)2.15650217
90Reduced antithrombin III activity (HP:0001976)2.13468437
91Cholecystitis (HP:0001082)2.08481146
92Abnormal gallbladder physiology (HP:0012438)2.08481146
93Amyloidosis (HP:0011034)2.07514476
94Brushfield spots (HP:0001088)2.05699401
95Abnormality of the Achilles tendon (HP:0005109)2.05331245
96Abnormal enzyme/coenzyme activity (HP:0012379)2.04561855
97Opisthotonus (HP:0002179)2.03009745
98Esophageal varix (HP:0002040)2.02804411
99Recurrent gram-negative bacterial infections (HP:0005420)2.00444027
100Hypochromic anemia (HP:0001931)1.99000829
101Hypophosphatemic rickets (HP:0004912)1.98684287
102Thrombophlebitis (HP:0004418)1.98623457
103Menorrhagia (HP:0000132)1.97889304
104Hyperphosphaturia (HP:0003109)1.91458231
105Abnormal cartilage morphology (HP:0002763)1.90367547
106Gingival bleeding (HP:0000225)1.89292739
107Back pain (HP:0003418)1.87911600
108Abnormality of the gallbladder (HP:0005264)1.86844145
109Nephrolithiasis (HP:0000787)1.86625104
110Hyperinsulinemic hypoglycemia (HP:0000825)1.83927460
111Hemorrhage of the eye (HP:0011885)1.83696794
112Confusion (HP:0001289)1.83273940
113Abnormality of transition element cation homeostasis (HP:0011030)1.82781218
114Abnormality of alkaline phosphatase activity (HP:0004379)1.81225838
115Megaloblastic anemia (HP:0001889)1.80239718
116Cerebral palsy (HP:0100021)1.77811797
117Stroke (HP:0001297)1.71061275
118Epistaxis (HP:0000421)1.70840777
119Pulmonary embolism (HP:0002204)1.70174871
120Abnormality of vitamin metabolism (HP:0100508)1.65879490
121Joint swelling (HP:0001386)1.55517022
122Abnormal urine phosphate concentration (HP:0012599)1.52568038
123Hypertriglyceridemia (HP:0002155)1.51626923
124Retinal atrophy (HP:0001105)1.48768896

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.64463741
2MUSK5.74258621
3FGFR44.44949406
4SIK14.05827966
5ERN14.01698900
6TESK23.72977986
7INSRR2.68514123
8PIM22.61178394
9TAOK32.52573366
10ERBB42.49041264
11MST1R2.18689228
12MAP2K42.10909477
13WNK42.05930743
14WNK32.00715227
15PKN22.00148426
16MAPK111.81040650
17TRIB31.73928756
18PTK2B1.73772949
19NME21.70335976
20FLT31.66957557
21PIK3CG1.58412636
22LMTK21.56806281
23STK38L1.55725775
24OXSR11.54230709
25OBSCN1.51298064
26ABL21.50302164
27TYK21.47335403
28ARAF1.43516915
29PTK61.42719427
30PINK11.40747441
31LATS11.40465255
32DAPK21.38047853
33GRK61.33527533
34FRK1.21072148
35KDR1.19318331
36MAP3K71.18919502
37NEK91.18143787
38TNK21.16228949
39MARK31.13835554
40JAK21.10792530
41FGFR21.10474608
42PRKAA21.09315197
43MAP2K31.06424986
44TBK11.05570971
45RPS6KA51.02658146
46CSNK1G20.97517781
47EPHB10.95707511
48CSNK1G30.94864491
49TESK10.94376611
50MAP3K30.93535532
51RPS6KC10.92574572
52RPS6KL10.92574572
53PRKCZ0.92142598
54MAP3K140.91435506
55TIE10.90400136
56CSNK1A1L0.88969735
57MAPK40.87862674
58RPS6KA60.87554350
59DYRK1B0.86567091
60IKBKB0.85976064
61MAP3K110.84982218
62ERBB20.84849436
63MAPK150.83080400
64MYLK0.82079917
65MET0.81621810
66GSK3A0.80766148
67SGK4940.79885346
68SGK2230.79885346
69MAP3K100.79666330
70SGK30.79529948
71PDK30.79414590
72PDK40.79414590
73JAK10.79101591
74PRKD20.78199113
75MAPK120.78013664
76MAP2K70.75597929
77CDK90.74509207
78PRKACG0.74480522
79PRPF4B0.72872884
80CDK190.71864252
81PRKAA10.70599276
82AKT20.69717524
83DYRK20.69181251
84TGFBR20.67962717
85KIT0.67850318
86MAP2K60.67771658
87PTK20.67356572
88DAPK30.65618111
89SGK20.65180330
90CDK60.64780644
91PDPK10.64245844
92CSK0.63092690
93CAMK2G0.62489554
94MAP2K20.61675531
95IRAK30.61353610
96NEK10.60773704
97RIPK10.56255335
98IKBKE0.51204664
99EPHA30.50815309
100JAK30.50475894
101EPHA40.49980054
102MAP3K10.49070006
103PRKACA0.47910830
104PRKCQ0.47329460
105CAMKK20.46095186
106RPS6KA20.45738152
107MAPK70.45348865
108CSF1R0.42159667
109CSNK1G10.41990113
110PIK3CA0.41589026
111NTRK30.41422230
112TAOK20.41411656
113CAMK1D0.41340726
114TAOK10.40587168
115PDK10.40467487
116PDK20.39294809
117IGF1R0.39049651
118PRKCG0.38669675
119FGFR30.38557183
120FER0.38082007
121STK390.37889853
122CSNK1A10.37437619
123GRK10.37403789
124STK380.36544571
125MAP2K10.35654161
126MAP3K50.34403453
127RPS6KA10.33718538
128MAPK30.33709423
129BCR0.33255638
130CSNK1D0.33081369
131DYRK30.33006269
132IRAK20.31582678
133CAMK40.31452639
134SIK20.31116696
135CDK40.30586705
136MTOR0.30048776
137MAP3K60.29903188
138PRKD10.29801988
139PRKACB0.29304097
140ICK0.28994046
141PRKCA0.28007827
142RET0.27865046
143EGFR0.27154761
144MAP3K130.26914324
145PKN10.26424402
146IRAK10.25224136
147PBK0.24545350
148PAK30.23424565

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.24528763
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.45473428
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.33646858
4Nitrogen metabolism_Homo sapiens_hsa009103.32171125
5Arginine biosynthesis_Homo sapiens_hsa002202.99016279
6Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.77085435
7Tryptophan metabolism_Homo sapiens_hsa003802.71861575
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.61169809
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.57649300
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.52996298
11Fatty acid degradation_Homo sapiens_hsa000712.51598445
12Complement and coagulation cascades_Homo sapiens_hsa046102.47015047
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.39677785
14Butanoate metabolism_Homo sapiens_hsa006502.39175695
15Peroxisome_Homo sapiens_hsa041462.19354537
16Propanoate metabolism_Homo sapiens_hsa006402.09162176
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.07361417
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.89819061
19Chemical carcinogenesis_Homo sapiens_hsa052041.88046264
20Histidine metabolism_Homo sapiens_hsa003401.86021376
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.85243835
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.84992857
23PPAR signaling pathway_Homo sapiens_hsa033201.82979324
24Fatty acid metabolism_Homo sapiens_hsa012121.82173319
25beta-Alanine metabolism_Homo sapiens_hsa004101.77167974
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.73921852
27Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.71149130
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.69623193
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.62787038
30Retinol metabolism_Homo sapiens_hsa008301.60453572
31Caffeine metabolism_Homo sapiens_hsa002321.59799906
32Selenocompound metabolism_Homo sapiens_hsa004501.58558164
33Phenylalanine metabolism_Homo sapiens_hsa003601.54565508
34Bile secretion_Homo sapiens_hsa049761.53131017
35Staphylococcus aureus infection_Homo sapiens_hsa051501.51979457
36Pyruvate metabolism_Homo sapiens_hsa006201.51892707
37Sulfur metabolism_Homo sapiens_hsa009201.46039216
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.39892541
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.36904895
40Tyrosine metabolism_Homo sapiens_hsa003501.35800452
41Cysteine and methionine metabolism_Homo sapiens_hsa002701.32958714
42Fatty acid elongation_Homo sapiens_hsa000621.28934295
43Starch and sucrose metabolism_Homo sapiens_hsa005001.28659035
44Folate biosynthesis_Homo sapiens_hsa007901.25203898
45Biosynthesis of amino acids_Homo sapiens_hsa012301.23642542
46Carbon metabolism_Homo sapiens_hsa012001.21887892
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20376557
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.14738248
49Steroid biosynthesis_Homo sapiens_hsa001001.12089253
50ABC transporters_Homo sapiens_hsa020101.07669293
51Arginine and proline metabolism_Homo sapiens_hsa003301.07139481
52Fat digestion and absorption_Homo sapiens_hsa049751.03876706
53Vitamin digestion and absorption_Homo sapiens_hsa049771.01425911
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.96565616
55Sulfur relay system_Homo sapiens_hsa041220.95189274
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.93606643
57Lysine degradation_Homo sapiens_hsa003100.87315660
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83922696
59Vitamin B6 metabolism_Homo sapiens_hsa007500.81025759
60Glutathione metabolism_Homo sapiens_hsa004800.80213363
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76575426
62Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.71988965
63Glycerolipid metabolism_Homo sapiens_hsa005610.70435599
64One carbon pool by folate_Homo sapiens_hsa006700.69846574
65Pentose phosphate pathway_Homo sapiens_hsa000300.60003623
66Metabolic pathways_Homo sapiens_hsa011000.49276659
67Fatty acid biosynthesis_Homo sapiens_hsa000610.38459432
68Fructose and mannose metabolism_Homo sapiens_hsa000510.32996243
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28637773
70Galactose metabolism_Homo sapiens_hsa000520.24770412
71Prion diseases_Homo sapiens_hsa050200.22877565
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22513433
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.21197011
74Insulin resistance_Homo sapiens_hsa049310.19799408
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.18504637
76Pertussis_Homo sapiens_hsa051330.17894011
77Linoleic acid metabolism_Homo sapiens_hsa005910.16498716
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.11066188
79Glucagon signaling pathway_Homo sapiens_hsa049220.06535242
80AMPK signaling pathway_Homo sapiens_hsa041520.00747920
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.00275377
82Renin secretion_Homo sapiens_hsa04924-0.2389023
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080-0.2384193
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2322024
85Phototransduction_Homo sapiens_hsa04744-0.2319937
86Systemic lupus erythematosus_Homo sapiens_hsa05322-0.2206769
87Vascular smooth muscle contraction_Homo sapiens_hsa04270-0.2102658
88Other glycan degradation_Homo sapiens_hsa00511-0.2092249
89Lysosome_Homo sapiens_hsa04142-0.2037113
90African trypanosomiasis_Homo sapiens_hsa05143-0.1994181
91Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1870296
92Hepatitis C_Homo sapiens_hsa05160-0.1817586
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1709906
94Amoebiasis_Homo sapiens_hsa05146-0.1563660
95Protein digestion and absorption_Homo sapiens_hsa04974-0.1561634
96Pyrimidine metabolism_Homo sapiens_hsa00240-0.1495771
97Mineral absorption_Homo sapiens_hsa04978-0.1477267
98Serotonergic synapse_Homo sapiens_hsa04726-0.1470289
99Regulation of autophagy_Homo sapiens_hsa04140-0.1419155
100Insulin signaling pathway_Homo sapiens_hsa04910-0.1383903
101Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1378873
102Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1334504
103Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1243038
104Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1033239
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0975093
106Renin-angiotensin system_Homo sapiens_hsa04614-0.0957465
107Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0913766
108Sphingolipid metabolism_Homo sapiens_hsa00600-0.0800739
109Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0751291
110Ether lipid metabolism_Homo sapiens_hsa00565-0.0566562
111Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563-0.0321422
112Circadian rhythm_Homo sapiens_hsa04710-0.0316622

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