TTC32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.68888650
2DNA deamination (GO:0045006)5.20731988
3viral transcription (GO:0019083)4.69485922
4translational termination (GO:0006415)4.56984818
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.52841485
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.38744775
7cotranslational protein targeting to membrane (GO:0006613)4.26917943
8protein targeting to ER (GO:0045047)4.24676452
9telomere maintenance via semi-conservative replication (GO:0032201)4.22682371
10translational elongation (GO:0006414)4.12601237
11deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.07665419
12protein localization to endoplasmic reticulum (GO:0070972)4.03330335
13establishment of protein localization to endoplasmic reticulum (GO:0072599)4.01945441
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.98699788
15maturation of SSU-rRNA (GO:0030490)3.92448962
16ribosomal small subunit biogenesis (GO:0042274)3.91666750
17DNA strand elongation involved in DNA replication (GO:0006271)3.90152821
18DNA strand elongation (GO:0022616)3.78264795
19cytochrome complex assembly (GO:0017004)3.75930773
20respiratory electron transport chain (GO:0022904)3.71692449
21electron transport chain (GO:0022900)3.68502155
22ATP synthesis coupled proton transport (GO:0015986)3.66522741
23energy coupled proton transport, down electrochemical gradient (GO:0015985)3.66522741
24GMP metabolic process (GO:0046037)3.62677187
25telomere maintenance via recombination (GO:0000722)3.55769373
26protein neddylation (GO:0045116)3.53971421
27cullin deneddylation (GO:0010388)3.53428824
28viral life cycle (GO:0019058)3.51676496
29ribosomal large subunit biogenesis (GO:0042273)3.43915702
30nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.43236694
31translational initiation (GO:0006413)3.43035382
32protein deneddylation (GO:0000338)3.41742042
33nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.39120917
34mannosylation (GO:0097502)3.38805292
35pteridine-containing compound biosynthetic process (GO:0042559)3.37737709
36rRNA modification (GO:0000154)3.32898514
37cellular protein complex disassembly (GO:0043624)3.29597712
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25901092
39RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25901092
40positive regulation of mitochondrial fission (GO:0090141)3.24701944
41DNA replication initiation (GO:0006270)3.21156412
42mitotic recombination (GO:0006312)3.20221400
43purine nucleotide salvage (GO:0032261)3.18177372
44chaperone-mediated protein transport (GO:0072321)3.18053740
45cellular ketone body metabolic process (GO:0046950)3.14441794
46L-phenylalanine metabolic process (GO:0006558)3.13997566
47erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.13997566
48GPI anchor metabolic process (GO:0006505)3.13058220
49translation (GO:0006412)3.10654514
50GPI anchor biosynthetic process (GO:0006506)3.10467635
51telomere maintenance via telomere lengthening (GO:0010833)3.05609529
52folic acid-containing compound biosynthetic process (GO:0009396)3.04866921
53pseudouridine synthesis (GO:0001522)3.04142309
54inositol phosphate catabolic process (GO:0071545)3.02877668
55inositol phosphate dephosphorylation (GO:0046855)3.02342399
56phosphorylated carbohydrate dephosphorylation (GO:0046838)3.02342399
57platelet dense granule organization (GO:0060155)3.01698923
58pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.00694848
59nucleoside salvage (GO:0043174)2.98579436
60pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.97903917
61pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.95976267
62deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.95920784
63glycine metabolic process (GO:0006544)2.95899900
64rRNA methylation (GO:0031167)2.93353599
65erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.91955650
66L-phenylalanine catabolic process (GO:0006559)2.91955650
67regulation of cilium movement (GO:0003352)2.91575745
68positive regulation of granulocyte differentiation (GO:0030854)2.90744661
69pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.90627525
70protein-cofactor linkage (GO:0018065)2.90526999
71nucleobase biosynthetic process (GO:0046112)2.88915293
72anterograde synaptic vesicle transport (GO:0048490)2.88124614
73protein complex disassembly (GO:0043241)2.87630172
74peptidyl-histidine modification (GO:0018202)2.86078948
75preassembly of GPI anchor in ER membrane (GO:0016254)2.85655521
76respiratory chain complex IV assembly (GO:0008535)2.85467314
77valine metabolic process (GO:0006573)2.84828941
78serine family amino acid biosynthetic process (GO:0009070)2.84180755
79purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.81981064
80C-terminal protein lipidation (GO:0006501)2.81785391
81single strand break repair (GO:0000012)2.81698488
82aggressive behavior (GO:0002118)2.80622362
83mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.80296964
84mitochondrial respiratory chain complex I assembly (GO:0032981)2.80296964
85NADH dehydrogenase complex assembly (GO:0010257)2.80296964
86regulation of glucokinase activity (GO:0033131)2.79799613
87regulation of hexokinase activity (GO:1903299)2.79799613
88ribonucleoprotein complex biogenesis (GO:0022613)2.79713366
89termination of RNA polymerase III transcription (GO:0006386)2.79446144
90transcription elongation from RNA polymerase III promoter (GO:0006385)2.79446144
91CENP-A containing nucleosome assembly (GO:0034080)2.78988605
92metallo-sulfur cluster assembly (GO:0031163)2.78854704
93iron-sulfur cluster assembly (GO:0016226)2.78854704
94macromolecular complex disassembly (GO:0032984)2.77755705
95organelle disassembly (GO:1903008)2.76774692
96nucleotide-excision repair, DNA gap filling (GO:0006297)2.76373587
97regulation of B cell apoptotic process (GO:0002902)2.75426919
98cysteine metabolic process (GO:0006534)2.74525283
99proteasome assembly (GO:0043248)2.73834133
100kinetochore assembly (GO:0051382)2.73735452
101oxidative phosphorylation (GO:0006119)2.73040426
102ketone body metabolic process (GO:1902224)2.72390781
103ubiquinone biosynthetic process (GO:0006744)2.72012429
104chromatin remodeling at centromere (GO:0031055)2.71426994
105nuclear-transcribed mRNA catabolic process (GO:0000956)2.69846402
106protein targeting to membrane (GO:0006612)2.68108182
107DNA ligation (GO:0006266)2.67038510
108L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.64446293
109S-adenosylmethionine metabolic process (GO:0046500)2.63699913
110purine nucleobase biosynthetic process (GO:0009113)2.62143648
111aromatic amino acid family catabolic process (GO:0009074)2.61779367
112pyrimidine dimer repair (GO:0006290)2.61433338
113pyrimidine nucleoside salvage (GO:0043097)2.60404656
114pyrimidine-containing compound salvage (GO:0008655)2.60404656
115histone mRNA metabolic process (GO:0008334)2.60201541
116disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.60088104
117killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.60088104
118formation of translation preinitiation complex (GO:0001731)2.59702487
119cellular component biogenesis (GO:0044085)2.58509488
120DNA unwinding involved in DNA replication (GO:0006268)2.58054706
121L-methionine salvage (GO:0071267)2.56718101
122L-methionine biosynthetic process (GO:0071265)2.56718101
123amino acid salvage (GO:0043102)2.56718101
124pyrimidine nucleotide catabolic process (GO:0006244)2.56481863
125water-soluble vitamin biosynthetic process (GO:0042364)2.55854170
126mRNA catabolic process (GO:0006402)2.55753001
127pyrimidine nucleoside biosynthetic process (GO:0046134)2.55572685
128inner mitochondrial membrane organization (GO:0007007)2.55207501
129DNA replication checkpoint (GO:0000076)2.55106668
130histone H2A acetylation (GO:0043968)2.54817306
131ribonucleoprotein complex disassembly (GO:0032988)2.54354088
132purine-containing compound salvage (GO:0043101)2.54335503
133protein targeting to mitochondrion (GO:0006626)2.54015068
134serine family amino acid metabolic process (GO:0009069)2.53943554
135exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.52777982
136C-terminal protein amino acid modification (GO:0018410)2.52419728
137centriole replication (GO:0007099)2.51956456
138tRNA processing (GO:0008033)2.51306813
139pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.50219763
140UMP metabolic process (GO:0046049)2.50219763
141pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.50219763
142UMP biosynthetic process (GO:0006222)2.50219763
143DNA demethylation (GO:0080111)2.50100204
144protein complex biogenesis (GO:0070271)2.49570153
145regulation of mitochondrial translation (GO:0070129)2.48597907
146IMP biosynthetic process (GO:0006188)2.48590152
147mitochondrial respiratory chain complex assembly (GO:0033108)2.48329040
148negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.47899202
149imidazole-containing compound metabolic process (GO:0052803)2.47676043
150L-serine metabolic process (GO:0006563)2.47119360
151protein localization to cilium (GO:0061512)2.47013015
152ubiquinone metabolic process (GO:0006743)2.46924579
153positive regulation of histone H3-K4 methylation (GO:0051571)2.46760312
154regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.46705110
155regulation of mitotic spindle checkpoint (GO:1903504)2.46705110
156tetrahydrofolate metabolic process (GO:0046653)2.46635080
157DNA replication-independent nucleosome assembly (GO:0006336)2.46256512
158DNA replication-independent nucleosome organization (GO:0034724)2.46256512
159DNA catabolic process, exonucleolytic (GO:0000738)2.45916681
160protein localization to mitochondrion (GO:0070585)2.45418815
161adenosine metabolic process (GO:0046085)2.45369121
1622-deoxyribonucleotide metabolic process (GO:0009394)2.45094605
163rRNA processing (GO:0006364)2.44407739
164DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.43691096
165RNA catabolic process (GO:0006401)2.43679415
166ribosome assembly (GO:0042255)2.42895447
167resolution of meiotic recombination intermediates (GO:0000712)2.42832141
168glyoxylate metabolic process (GO:0046487)2.42398439
169hydrogen ion transmembrane transport (GO:1902600)2.42143755
170axoneme assembly (GO:0035082)2.41788411
171positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.41436891
172negative regulation of B cell apoptotic process (GO:0002903)2.41406899
173endosome to pigment granule transport (GO:0043485)2.41209555
174endosome to melanosome transport (GO:0035646)2.41209555
175antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.40589022
176antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.40589022
177deoxyribose phosphate biosynthetic process (GO:0046385)2.40509665
1782-deoxyribonucleotide biosynthetic process (GO:0009265)2.40509665
179pteridine-containing compound metabolic process (GO:0042558)2.40313616
180mismatch repair (GO:0006298)2.40066711
181kinetochore organization (GO:0051383)2.39141852
182prenylation (GO:0097354)2.38902551

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.58675795
2* MYC_18555785_ChIP-Seq_MESCs_Mouse3.69110783
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.65728582
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.24362969
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.17677336
6ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.05899246
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.95964643
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.79513682
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.76160032
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.70762747
11ZNF274_21170338_ChIP-Seq_K562_Hela2.68128706
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.53506529
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.50206439
14SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.42708952
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.38698212
16VDR_22108803_ChIP-Seq_LS180_Human2.37145590
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36595446
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.36587479
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.32942451
20NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.28824395
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.27869655
22CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.27070775
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.22857188
24IGF1R_20145208_ChIP-Seq_DFB_Human2.17960318
25* VDR_23849224_ChIP-Seq_CD4+_Human2.16883441
26* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.14109329
27EGR1_23403033_ChIP-Seq_LIVER_Mouse2.13742997
28POU3F2_20337985_ChIP-ChIP_501MEL_Human2.09783093
29MYC_19079543_ChIP-ChIP_MESCs_Mouse2.06702853
30* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.06145517
31CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.04863531
32XRN2_22483619_ChIP-Seq_HELA_Human2.01818780
33* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99634882
34FUS_26573619_Chip-Seq_HEK293_Human1.98573943
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97221288
36* FOXP3_21729870_ChIP-Seq_TREG_Human1.96282639
37* DCP1A_22483619_ChIP-Seq_HELA_Human1.94881091
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.92237411
39EWS_26573619_Chip-Seq_HEK293_Human1.90341119
40IRF8_22096565_ChIP-ChIP_GC-B_Human1.90248087
41PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.89443183
42RXR_22158963_ChIP-Seq_LIVER_Mouse1.88297469
43CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.86912249
44ERG_20887958_ChIP-Seq_HPC-7_Mouse1.85393623
45* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.85378851
46* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.82733647
47* SRF_21415370_ChIP-Seq_HL-1_Mouse1.82278009
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.80785379
49* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.79621713
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79330213
51FOXM1_23109430_ChIP-Seq_U2OS_Human1.77546003
52NOTCH1_21737748_ChIP-Seq_TLL_Human1.74656783
53* GABP_19822575_ChIP-Seq_HepG2_Human1.71433647
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.69483541
55TAF15_26573619_Chip-Seq_HEK293_Human1.67884219
56IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.67303204
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.62341545
58SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.61007567
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.53766260
60* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.50366665
61AR_21909140_ChIP-Seq_LNCAP_Human1.49100655
62TTF2_22483619_ChIP-Seq_HELA_Human1.47862987
63RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.47638545
64SCL_19346495_ChIP-Seq_HPC-7_Human1.47610011
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.46027049
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.45789083
67GATA1_22025678_ChIP-Seq_K562_Human1.45019639
68TP53_22573176_ChIP-Seq_HFKS_Human1.42920225
69MYC_22102868_ChIP-Seq_BL_Human1.42074003
70MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.39208270
71THAP11_20581084_ChIP-Seq_MESCs_Mouse1.38664321
72CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.38661253
73ELK1_19687146_ChIP-ChIP_HELA_Human1.35270122
74* SPI1_23547873_ChIP-Seq_NB4_Human1.34410038
75GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.34409031
76CIITA_25753668_ChIP-Seq_RAJI_Human1.34180854
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.33591556
78ER_23166858_ChIP-Seq_MCF-7_Human1.33422753
79MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32976689
80HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.32645082
81CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.31135811
82MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.27392074
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24136407
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22922376
85ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21085417
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20852683
87MYB_21317192_ChIP-Seq_ERMYB_Mouse1.19414633
88* VDR_21846776_ChIP-Seq_THP-1_Human1.19142505
89RBPJ_22232070_ChIP-Seq_NCS_Mouse1.19038239
90P300_19829295_ChIP-Seq_ESCs_Human1.15401061
91ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13582141
92IRF1_19129219_ChIP-ChIP_H3396_Human1.12276541
93POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.12078030
94PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11975323
95* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.11409648
96EGR1_19374776_ChIP-ChIP_THP-1_Human1.09727037
97CTBP2_25329375_ChIP-Seq_LNCAP_Human1.08337905
98RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07422896
99TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05403123
100* GATA3_26560356_Chip-Seq_TH2_Human1.04882014
101HTT_18923047_ChIP-ChIP_STHdh_Human1.04759635
102NANOG_18555785_ChIP-Seq_MESCs_Mouse1.03741180
103PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.03574035
104TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02420327
105CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02298784
106FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02143945
107FOXA1_25329375_ChIP-Seq_VCAP_Human1.02143945
108GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01904966
109MYC_18940864_ChIP-ChIP_HL60_Human1.01830012
110E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01686982
111* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01351363
112POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.00937252
113CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99578692
114LXR_22158963_ChIP-Seq_LIVER_Mouse0.99373789
115YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.99315122
116STAT4_19710469_ChIP-ChIP_TH1__Mouse0.98468548
117KDM5A_27292631_Chip-Seq_BREAST_Human0.98340926
118CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98223067
119* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96604594
120NANOG_19829295_ChIP-Seq_ESCs_Human0.96505002
121SOX2_19829295_ChIP-Seq_ESCs_Human0.96505002
122GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96350407
123EZH2_27294783_Chip-Seq_NPCs_Mouse0.96141035
124STAT3_1855785_ChIP-Seq_MESCs_Mouse0.95968813
125SALL4_22934838_ChIP-ChIP_CD34+_Human0.95435291
126MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.93648398
127CBP_20019798_ChIP-Seq_JUKART_Human0.93038367
128IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93038367
129MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.92490544
130HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.92309816
131LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91986853
132FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91791515
133FOXA1_21572438_ChIP-Seq_LNCaP_Human0.91757525
134FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91469607
135PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91279327
136AR_20517297_ChIP-Seq_VCAP_Human0.91135505
137MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.90790710
138TFEB_21752829_ChIP-Seq_HELA_Human0.90705037
139NCOR_22424771_ChIP-Seq_293T_Human0.90560105
140IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.90560093
141PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.88379413
142CTBP1_25329375_ChIP-Seq_LNCAP_Human0.88067489

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system3.97215579
2MP0005360_urolithiasis3.65880663
3MP0003806_abnormal_nucleotide_metabolis3.45142859
4MP0003693_abnormal_embryo_hatching3.33989038
5MP0005365_abnormal_bile_salt3.13988608
6MP0005085_abnormal_gallbladder_physiolo2.86158777
7MP0002396_abnormal_hematopoietic_system2.67589923
8MP0008875_abnormal_xenobiotic_pharmacok2.36520612
9MP0008995_early_reproductive_senescence2.35990598
10MP0001529_abnormal_vocalization2.31640984
11MP0002837_dystrophic_cardiac_calcinosis2.30070593
12MP0004957_abnormal_blastocyst_morpholog2.16828911
13MP0003186_abnormal_redox_activity2.12581750
14MP0006292_abnormal_olfactory_placode2.07795124
15MP0003786_premature_aging2.07766918
16MP0010094_abnormal_chromosome_stability2.06373537
17MP0009379_abnormal_foot_pigmentation2.05565455
18MP0000372_irregular_coat_pigmentation2.04319991
19MP0008877_abnormal_DNA_methylation2.02081359
20MP0002638_abnormal_pupillary_reflex2.00611550
21MP0006036_abnormal_mitochondrial_physio2.00156504
22MP0002102_abnormal_ear_morphology1.92185864
23MP0001853_heart_inflammation1.85224939
24MP0006072_abnormal_retinal_apoptosis1.84643281
25MP0001835_abnormal_antigen_presentation1.84360686
26MP0000685_abnormal_immune_system1.79527597
27MP0003787_abnormal_imprinting1.78555484
28MP0009046_muscle_twitch1.78542923
29MP0005646_abnormal_pituitary_gland1.76499541
30MP0002277_abnormal_respiratory_mucosa1.76065007
31MP0002822_catalepsy1.75956871
32MP0009785_altered_susceptibility_to1.73246301
33MP0004147_increased_porphyrin_level1.72131503
34MP0008058_abnormal_DNA_repair1.69364659
35MP0001764_abnormal_homeostasis1.67122176
36MP0005645_abnormal_hypothalamus_physiol1.66972003
37MP0002163_abnormal_gland_morphology1.64457619
38MP0005075_abnormal_melanosome_morpholog1.63829785
39MP0003077_abnormal_cell_cycle1.62534328
40MP0005379_endocrine/exocrine_gland_phen1.61464675
41MP0001984_abnormal_olfaction1.60735062
42MP0003763_abnormal_thymus_physiology1.59612363
43MP0000490_abnormal_crypts_of1.57968301
44MP0005332_abnormal_amino_acid1.57841976
45MP0006054_spinal_hemorrhage1.56558222
46MP0005319_abnormal_enzyme/_coenzyme1.54761413
47MP0009840_abnormal_foam_cell1.54313095
48MP0004142_abnormal_muscle_tone1.53898489
49MP0003436_decreased_susceptibility_to1.52037332
50MP0008007_abnormal_cellular_replicative1.50833204
51MP0009697_abnormal_copulation1.46359444
52MP0005671_abnormal_response_to1.42395900
53MP0002132_abnormal_respiratory_system1.42332960
54MP0003111_abnormal_nucleus_morphology1.42019087
55MP0005464_abnormal_platelet_physiology1.40949434
56MP0009333_abnormal_splenocyte_physiolog1.39348425
57MP0003121_genomic_imprinting1.39069809
58MP0005025_abnormal_response_to1.38346417
59MP0008469_abnormal_protein_level1.38024829
60MP0005253_abnormal_eye_physiology1.37688067
61MP0000609_abnormal_liver_physiology1.37126171
62MP0010329_abnormal_lipoprotein_level1.36330425
63MP0003724_increased_susceptibility_to1.35430382
64MP0003880_abnormal_central_pattern1.32859680
65MP0005551_abnormal_eye_electrophysiolog1.30957098
66MP0003122_maternal_imprinting1.30657731
67MP0000689_abnormal_spleen_morphology1.29752740
68MP0002398_abnormal_bone_marrow1.29356882
69MP0001666_abnormal_nutrient_absorption1.28002555
70MP0003252_abnormal_bile_duct1.26944120
71MP0002138_abnormal_hepatobiliary_system1.26269014
72MP0003195_calcinosis1.25157817
73MP0003656_abnormal_erythrocyte_physiolo1.24860447
74MP0001800_abnormal_humoral_immune1.24645831
75MP0004808_abnormal_hematopoietic_stem1.23971794
76MP0009643_abnormal_urine_homeostasis1.23891970
77MP0001545_abnormal_hematopoietic_system1.23820433
78MP0005397_hematopoietic_system_phenotyp1.23820433
79MP0003191_abnormal_cellular_cholesterol1.22987413
80MP0000465_gastrointestinal_hemorrhage1.22215570
81MP0008789_abnormal_olfactory_epithelium1.22214595
82MP0006276_abnormal_autonomic_nervous1.21374409
83MP0001905_abnormal_dopamine_level1.19507907
84MP0002722_abnormal_immune_system1.18556136
85MP0005220_abnormal_exocrine_pancreas1.17325654
86MP0005174_abnormal_tail_pigmentation1.16236404
87MP0000598_abnormal_liver_morphology1.16074988
88MP0006035_abnormal_mitochondrial_morpho1.15956558
89MP0002429_abnormal_blood_cell1.14832847
90MP0000631_abnormal_neuroendocrine_gland1.14532204
91MP0009053_abnormal_anal_canal1.14240368
92MP0002723_abnormal_immune_serum1.14011676
93MP0000716_abnormal_immune_system1.13484316
94MP0005636_abnormal_mineral_homeostasis1.12946137
95MP0002452_abnormal_antigen_presenting1.11669396
96MP0002019_abnormal_tumor_incidence1.10564014
97MP0008872_abnormal_physiological_respon1.09597777
98MP0002420_abnormal_adaptive_immunity1.09551143
99MP0005000_abnormal_immune_tolerance1.07999098
100MP0003718_maternal_effect1.07528333
101MP0000516_abnormal_urinary_system1.07320648
102MP0005367_renal/urinary_system_phenotyp1.07320648
103MP0001819_abnormal_immune_cell1.07149450
104MP0010155_abnormal_intestine_physiology1.04474954
105MP0002419_abnormal_innate_immunity1.04431175
106MP0008057_abnormal_DNA_replication1.04033958
107MP0003868_abnormal_feces_composition1.03994336
108MP0001929_abnormal_gametogenesis1.03139605
109MP0000647_abnormal_sebaceous_gland1.02554730
110MP0005389_reproductive_system_phenotype1.01602630
111MP0005584_abnormal_enzyme/coenzyme_acti1.01348486
112MP0001845_abnormal_inflammatory_respons1.01327062
113MP0001968_abnormal_touch/_nociception0.98112471
114MP0001986_abnormal_taste_sensitivity0.98091859
115MP0002095_abnormal_skin_pigmentation0.97450654
116MP0002876_abnormal_thyroid_physiology0.96737696
117MP0002148_abnormal_hypersensitivity_rea0.96358772
118MP0000358_abnormal_cell_content/0.95199626
119MP0009764_decreased_sensitivity_to0.94941341
120MP0005083_abnormal_biliary_tract0.94908320
121MP0009763_increased_sensitivity_to0.94748472
122MP0001873_stomach_inflammation0.94238907
123MP0003011_delayed_dark_adaptation0.94059891
124MP0003698_abnormal_male_reproductive0.92630152
125MP0002166_altered_tumor_susceptibility0.92485951
126MP0002928_abnormal_bile_duct0.92396392
127MP0002234_abnormal_pharynx_morphology0.91460229
128MP0002160_abnormal_reproductive_system0.91041553
129MP0000703_abnormal_thymus_morphology0.90774595
130MP0000313_abnormal_cell_death0.90381761
131MP0000653_abnormal_sex_gland0.89543574
132MP0002736_abnormal_nociception_after0.89033542
133MP0005535_abnormal_body_temperature0.88755525
134MP0005187_abnormal_penis_morphology0.88201127
135MP0002938_white_spotting0.87095044
136MP0005394_taste/olfaction_phenotype0.86102989
137MP0005499_abnormal_olfactory_system0.86102989
138MP0002210_abnormal_sex_determination0.85098056
139MP0001145_abnormal_male_reproductive0.85049493
140MP0008932_abnormal_embryonic_tissue0.84609890
141MP0005084_abnormal_gallbladder_morpholo0.84425226
142MP0009745_abnormal_behavioral_response0.82663528
143MP0004133_heterotaxia0.81929167
144MP0005647_abnormal_sex_gland0.81861248
145MP0004019_abnormal_vitamin_homeostasis0.81655393
146MP0002405_respiratory_system_inflammati0.80043008
147MP0001944_abnormal_pancreas_morphology0.78699364
148MP0003221_abnormal_cardiomyocyte_apopto0.78629653
149MP0005266_abnormal_metabolism0.78174145
150MP0002653_abnormal_ependyma_morphology0.78136228
151MP0003646_muscle_fatigue0.78096041
152MP0002118_abnormal_lipid_homeostasis0.77635020
153MP0009642_abnormal_blood_homeostasis0.77136307
154MP0005387_immune_system_phenotype0.74412464
155MP0001790_abnormal_immune_system0.74412464
156MP0005410_abnormal_fertilization0.73184615
157MP0002272_abnormal_nervous_system0.72293508
158MP0001919_abnormal_reproductive_system0.71902870
159MP0004145_abnormal_muscle_electrophysio0.70477530
160MP0001293_anophthalmia0.69756915
161MP0002909_abnormal_adrenal_gland0.69481308
162MP0009384_cardiac_valve_regurgitation0.68918028
163MP0000858_altered_metastatic_potential0.68512017
164MP0002006_tumorigenesis0.68479179
165MP0002693_abnormal_pancreas_physiology0.68147611
166MP0003567_abnormal_fetal_cardiomyocyte0.68041534

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.35364770
2Progressive macrocephaly (HP:0004481)4.28302039
3Abnormal number of erythroid precursors (HP:0012131)3.96809225
4Abnormality of cells of the erythroid lineage (HP:0012130)3.95174342
5Reticulocytopenia (HP:0001896)3.81552578
6Hepatic necrosis (HP:0002605)3.62310443
7Aplastic anemia (HP:0001915)3.61250928
8Type I transferrin isoform profile (HP:0003642)3.59236620
9Hypoglycemic coma (HP:0001325)3.41041305
10Thrombocytosis (HP:0001894)3.40689583
11Hepatocellular necrosis (HP:0001404)3.30059562
12Prolonged partial thromboplastin time (HP:0003645)3.27247120
13Reduced antithrombin III activity (HP:0001976)3.25938786
14Hypobetalipoproteinemia (HP:0003563)3.23641389
15Decreased activity of mitochondrial respiratory chain (HP:0008972)3.13374487
16Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.13374487
17Abnormality of monocarboxylic acid metabolism (HP:0010996)3.12486402
18Medial flaring of the eyebrow (HP:0010747)3.08038679
19Generalized aminoaciduria (HP:0002909)3.04464347
20Pancreatic cysts (HP:0001737)2.94984803
21Abnormality of midbrain morphology (HP:0002418)2.92849870
22Molar tooth sign on MRI (HP:0002419)2.92849870
23Abnormal glycosylation (HP:0012345)2.89482904
24Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.89482904
25Abnormal protein N-linked glycosylation (HP:0012347)2.89482904
26Abnormal protein glycosylation (HP:0012346)2.89482904
27Macrocytic anemia (HP:0001972)2.88157180
28Abnormality of fatty-acid metabolism (HP:0004359)2.81136945
29Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.79600902
30Abnormality of pyrimidine metabolism (HP:0004353)2.79414465
31Intrahepatic cholestasis (HP:0001406)2.76809382
32Hyperglycinemia (HP:0002154)2.76617503
33Hyperammonemia (HP:0001987)2.73772625
34Dicarboxylic aciduria (HP:0003215)2.73486749
35Abnormality of dicarboxylic acid metabolism (HP:0010995)2.73486749
36IgM deficiency (HP:0002850)2.65198541
37Lipid accumulation in hepatocytes (HP:0006561)2.65030767
38Pallor (HP:0000980)2.64522123
39Hypothermia (HP:0002045)2.64002742
40Oral leukoplakia (HP:0002745)2.63909850
41Pancreatic fibrosis (HP:0100732)2.62653554
42Mitochondrial inheritance (HP:0001427)2.61554536
43True hermaphroditism (HP:0010459)2.59492829
44Abnormality of the columella (HP:0009929)2.58314297
45Increased serum lactate (HP:0002151)2.58139140
46Respiratory failure (HP:0002878)2.55363376
47Methylmalonic acidemia (HP:0002912)2.55321093
48Increased CSF lactate (HP:0002490)2.54551285
49Congenital primary aphakia (HP:0007707)2.50391504
50Acute encephalopathy (HP:0006846)2.49921204
51Lactic acidosis (HP:0003128)2.47187615
52Increased muscle lipid content (HP:0009058)2.46858149
53Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.45417661
54Birth length less than 3rd percentile (HP:0003561)2.44511704
55Hyperbilirubinemia (HP:0002904)2.44279688
56Hyperinsulinemic hypoglycemia (HP:0000825)2.42863449
57Nephrogenic diabetes insipidus (HP:0009806)2.40007107
58Gait imbalance (HP:0002141)2.38732152
59Cerebral edema (HP:0002181)2.38620024
60Increased hepatocellular lipid droplets (HP:0006565)2.38475326
61Increased intramyocellular lipid droplets (HP:0012240)2.37066497
62Ketosis (HP:0001946)2.36942941
63Optic disc pallor (HP:0000543)2.34969130
64Abnormality of serum amino acid levels (HP:0003112)2.34011276
65Type II lissencephaly (HP:0007260)2.32568695
66Acute necrotizing encephalopathy (HP:0006965)2.30543743
67Abnormality of the intrinsic pathway (HP:0010989)2.29308788
68Hyperglycinuria (HP:0003108)2.28820612
69Nephronophthisis (HP:0000090)2.27788194
70Abnormal mitochondria in muscle tissue (HP:0008316)2.27573142
71Abnormality of the proximal phalanges of the hand (HP:0009834)2.26693481
72Pancytopenia (HP:0001876)2.25621701
73Microretrognathia (HP:0000308)2.25190073
74Lethargy (HP:0001254)2.23951264
75Exercise intolerance (HP:0003546)2.22717162
76Late onset (HP:0003584)2.22134714
77Elevated erythrocyte sedimentation rate (HP:0003565)2.21512393
78Petechiae (HP:0000967)2.19886694
79Abnormality of glycine metabolism (HP:0010895)2.19685241
80Abnormality of serine family amino acid metabolism (HP:0010894)2.19685241
81Renal cortical cysts (HP:0000803)2.16533506
823-Methylglutaconic aciduria (HP:0003535)2.16382314
83Microvesicular hepatic steatosis (HP:0001414)2.14030113
84Exertional dyspnea (HP:0002875)2.12214870
85Abnormal platelet function (HP:0011869)2.11945808
86Impaired platelet aggregation (HP:0003540)2.11945808
87Nausea (HP:0002018)2.10576302
88Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.08726350
89Leukodystrophy (HP:0002415)2.08341959
90Hypomagnesemia (HP:0002917)2.06110222
91Abnormality of the common coagulation pathway (HP:0010990)2.04476788
92Renal Fanconi syndrome (HP:0001994)2.04437976
93Joint hemorrhage (HP:0005261)2.03748794
94Hypoglycemic seizures (HP:0002173)2.02556685
95Epistaxis (HP:0000421)2.01282770
96Abnormality of nucleobase metabolism (HP:0010932)2.00931198
97Poikiloderma (HP:0001029)2.00570561
98Multiple enchondromatosis (HP:0005701)2.00549837
99Deep venous thrombosis (HP:0002625)2.00378438
100Delayed CNS myelination (HP:0002188)2.00149393
101Glycosuria (HP:0003076)1.99845325
102Abnormality of urine glucose concentration (HP:0011016)1.99845325
103Congenital stationary night blindness (HP:0007642)1.99314518
104Abnormality of the heme biosynthetic pathway (HP:0010472)1.98729438
105Methylmalonic aciduria (HP:0012120)1.97062226
106Ketoacidosis (HP:0001993)1.96547566
107Severe muscular hypotonia (HP:0006829)1.95958327
108Abnormality of renal resorption (HP:0011038)1.94941239
109Xanthomatosis (HP:0000991)1.94768551
110Respiratory difficulties (HP:0002880)1.94595724
111Tubulointerstitial nephritis (HP:0001970)1.93442636
112Abnormality of T cell physiology (HP:0011840)1.93017887
113Prolonged bleeding time (HP:0003010)1.92651289
114Metabolic acidosis (HP:0001942)1.91965921
115Hyperlipoproteinemia (HP:0010980)1.91521680
116Abolished electroretinogram (ERG) (HP:0000550)1.91244728
117Aplasia/Hypoplasia of the sacrum (HP:0008517)1.91127796
118CNS demyelination (HP:0007305)1.90980679
119Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89761942
120Abnormality of alanine metabolism (HP:0010916)1.89761942
121Hyperalaninemia (HP:0003348)1.89761942
122Opisthotonus (HP:0002179)1.88053603
123Panhypogammaglobulinemia (HP:0003139)1.86822677
124Hypolipoproteinemia (HP:0010981)1.86602665
125Fat malabsorption (HP:0002630)1.85572997
126Abnormality of B cell number (HP:0010975)1.85029517
127B lymphocytopenia (HP:0010976)1.85029517
128Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.83177007
129Abnormality of methionine metabolism (HP:0010901)1.82784495
130Abnormality of aspartate family amino acid metabolism (HP:0010899)1.82142709
131Decreased electroretinogram (ERG) amplitude (HP:0000654)1.81461919
132Cerebellar dysplasia (HP:0007033)1.77489766
133Attenuation of retinal blood vessels (HP:0007843)1.77153520
134Median cleft lip (HP:0000161)1.75385588
135Sclerocornea (HP:0000647)1.73381870
136Severe combined immunodeficiency (HP:0004430)1.72675321
137Aplasia/hypoplasia of the uterus (HP:0008684)1.71740914
138Abnormal rod and cone electroretinograms (HP:0008323)1.71669597
139Degeneration of anterior horn cells (HP:0002398)1.71498904
140Abnormality of the anterior horn cell (HP:0006802)1.71498904
141Abnormality of vitamin B metabolism (HP:0004340)1.71075800
142Abnormality of the renal medulla (HP:0100957)1.70818924
143Tetany (HP:0001281)1.70310852
144Brushfield spots (HP:0001088)1.69401877
145Male pseudohermaphroditism (HP:0000037)1.68990417
146Congenital hepatic fibrosis (HP:0002612)1.67997672
147Abnormality of the renal cortex (HP:0011035)1.65138460
148Genital tract atresia (HP:0001827)1.63855340
149X-linked dominant inheritance (HP:0001423)1.63757718
150Abnormality of macular pigmentation (HP:0008002)1.62098783
151Oculomotor apraxia (HP:0000657)1.60667377
152Bile duct proliferation (HP:0001408)1.57865289
153Abnormal biliary tract physiology (HP:0012439)1.57865289
154Emotional lability (HP:0000712)1.57738849
155Constricted visual fields (HP:0001133)1.56302464
156Postaxial foot polydactyly (HP:0001830)1.55862485
157Vaginal atresia (HP:0000148)1.55667533

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.56257857
2BCKDK3.48581835
3FRK3.33353406
4WEE13.25924681
5NME23.22612586
6MAP4K23.03726831
7FLT32.83746696
8MAP3K42.51207587
9BUB12.39633095
10BRSK22.26184205
11MAP2K72.25373650
12ACVR1B2.20472893
13MAP4K12.19511991
14EIF2AK12.07632078
15PINK12.01890219
16PASK2.00819717
17IRAK41.96814988
18KIT1.95668247
19IRAK31.92802103
20VRK11.88089225
21EIF2AK31.84028900
22TEC1.80892678
23BCR1.78617980
24NUAK11.75215697
25WNK41.73122545
26WNK31.64440679
27KDR1.62384740
28RPS6KA41.62355241
29DYRK31.59249034
30CSNK1G31.58484371
31PIM21.55888806
32BTK1.55603127
33CDC71.55449127
34ERN11.54087340
35MAP3K111.48849962
36MAP2K31.42150220
37CSNK1G21.39489689
38CSNK1G11.39265065
39OXSR11.38632141
40PDK21.35620192
41SRPK11.30965693
42MAPK131.30348036
43STK391.27093434
44TBK11.27085004
45LRRK21.26875560
46PIK3CG1.25028874
47ZAP701.24193036
48CSNK1A1L1.22915619
49TLK11.19118291
50VRK21.17420720
51TGFBR11.15554050
52TYK21.14497574
53CSF1R1.14326796
54TRIM281.13066138
55CDK71.12984356
56NEK21.11095703
57ERBB31.10759534
58NLK1.09036137
59TAOK31.08341519
60MAPK111.07749195
61RIPK41.06865806
62CDK81.06482091
63CDK41.05241082
64INSRR1.03141127
65MAP2K41.02841592
66BLK1.00003729
67MKNK10.99807628
68GRK10.99170473
69BMPR20.98255452
70BMPR1B0.96201780
71TESK20.93901579
72AURKB0.93184354
73TNIK0.91941578
74TXK0.91189953
75IKBKE0.90374937
76PKN20.89204218
77PLK20.86820060
78NEK90.86651421
79DAPK20.84524832
80CDK30.84002113
81PHKG20.83800075
82PHKG10.83800075
83MKNK20.83587384
84PLK30.83307718
85CLK10.83277936
86ATR0.82864808
87PRKCQ0.82358675
88IRAK20.82346972
89IRAK10.82066682
90PLK10.81274694
91NEK10.79711375
92BRSK10.79599904
93MST40.79391412
94MAP3K100.79386289
95CAMKK20.76695621
96RPS6KB20.74982014
97MUSK0.74881416
98DYRK20.74571473
99SYK0.73727201
100LYN0.73669134
101JAK30.72446934
102NME10.72416603
103ABL20.71177728
104PIM10.70970357
105MYLK0.70959376
106TTK0.69774092
107STK40.69378378
108PBK0.65820702
109DAPK10.64907871
110SCYL20.63834110
111PLK40.62936073
112PRKG20.62777516
113MAP3K80.62527042
114AURKA0.62092863
115MAP3K50.60439556
116ZAK0.58551230
117EIF2AK20.58507629
118IKBKB0.57398981
119TNK20.55546674
120CSNK2A10.55078450
121STK100.54870424
122MAP2K60.54737951
123ADRBK20.52946389
124ATM0.52661113
125CCNB10.52019286
126EPHA30.51473385
127ITK0.50986837
128TIE10.50788619
129MAPK40.49396448
130PAK30.48480677
131CSNK2A20.48304736
132PAK40.47899812
133MAP3K120.47816293
134MARK30.46717681
135HIPK20.46650466
136YES10.46597569
137STK240.46593817
138PRKCG0.46160088
139PRKCE0.45899709
140DYRK1B0.45709844
141TGFBR20.45641155
142UHMK10.44680877
143MAP3K30.44009471
144RPS6KA50.42362482
145OBSCN0.41955498
146PKN10.41731755
147LCK0.41557712
148ILK0.41443226
149GRK70.41216902
150MAPKAPK30.40767714

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.71268473
2Ribosome_Homo sapiens_hsa030103.66101888
3Mismatch repair_Homo sapiens_hsa034302.74639630
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.59821276
5Base excision repair_Homo sapiens_hsa034102.24782199
6Protein export_Homo sapiens_hsa030602.21305908
7Folate biosynthesis_Homo sapiens_hsa007902.18228117
8Pyrimidine metabolism_Homo sapiens_hsa002402.15409964
9Proteasome_Homo sapiens_hsa030502.13297595
10Homologous recombination_Homo sapiens_hsa034402.07244175
11Sulfur relay system_Homo sapiens_hsa041222.06703746
12Alzheimers disease_Homo sapiens_hsa050102.05213513
13Primary bile acid biosynthesis_Homo sapiens_hsa001202.02673443
14One carbon pool by folate_Homo sapiens_hsa006701.99929315
15Drug metabolism - other enzymes_Homo sapiens_hsa009831.93429447
16RNA polymerase_Homo sapiens_hsa030201.90518506
17Nucleotide excision repair_Homo sapiens_hsa034201.81932371
18Spliceosome_Homo sapiens_hsa030401.81740041
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.79781058
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.71912803
21Collecting duct acid secretion_Homo sapiens_hsa049661.68552407
22Type I diabetes mellitus_Homo sapiens_hsa049401.68394179
23Fatty acid degradation_Homo sapiens_hsa000711.58750390
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.56403085
25Regulation of autophagy_Homo sapiens_hsa041401.55616483
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.53672089
27Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.52770446
28Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.49585376
29Peroxisome_Homo sapiens_hsa041461.49485098
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.48404538
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48249533
32Selenocompound metabolism_Homo sapiens_hsa004501.48155105
33Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43152387
34Propanoate metabolism_Homo sapiens_hsa006401.41325263
35Caffeine metabolism_Homo sapiens_hsa002321.36510454
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.35357257
37Tryptophan metabolism_Homo sapiens_hsa003801.29233058
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.29161178
39Pentose phosphate pathway_Homo sapiens_hsa000301.26470574
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23664638
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.21493470
42Non-homologous end-joining_Homo sapiens_hsa034501.21392926
43Asthma_Homo sapiens_hsa053101.20373289
44Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19410010
45Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.18012890
46Phototransduction_Homo sapiens_hsa047441.13574437
47Carbon metabolism_Homo sapiens_hsa012001.10829470
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10179278
49Biosynthesis of amino acids_Homo sapiens_hsa012301.06170693
50RNA transport_Homo sapiens_hsa030131.05590095
51beta-Alanine metabolism_Homo sapiens_hsa004101.04672266
52Allograft rejection_Homo sapiens_hsa053301.04232357
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02801401
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02515752
55RNA degradation_Homo sapiens_hsa030181.01045003
56Cardiac muscle contraction_Homo sapiens_hsa042601.00585460
57Autoimmune thyroid disease_Homo sapiens_hsa053201.00060188
58Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.97876728
59Complement and coagulation cascades_Homo sapiens_hsa046100.97438084
60Purine metabolism_Homo sapiens_hsa002300.97301926
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.96668307
622-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96046727
63N-Glycan biosynthesis_Homo sapiens_hsa005100.95880266
64Histidine metabolism_Homo sapiens_hsa003400.94369756
65Parkinsons disease_Homo sapiens_hsa050120.94212320
66Glutathione metabolism_Homo sapiens_hsa004800.93823731
67Chemical carcinogenesis_Homo sapiens_hsa052040.92452074
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.92139863
69Fanconi anemia pathway_Homo sapiens_hsa034600.90851030
70Graft-versus-host disease_Homo sapiens_hsa053320.89888494
71Arginine biosynthesis_Homo sapiens_hsa002200.88462717
72Sulfur metabolism_Homo sapiens_hsa009200.86930773
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.85158641
74Cell cycle_Homo sapiens_hsa041100.83974540
75Nitrogen metabolism_Homo sapiens_hsa009100.83201176
76Starch and sucrose metabolism_Homo sapiens_hsa005000.82467849
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.80756716
78Oxidative phosphorylation_Homo sapiens_hsa001900.80566345
79Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.79887515
80Primary immunodeficiency_Homo sapiens_hsa053400.77102192
81Systemic lupus erythematosus_Homo sapiens_hsa053220.76819788
82Rheumatoid arthritis_Homo sapiens_hsa053230.76654020
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75378769
84Staphylococcus aureus infection_Homo sapiens_hsa051500.75256751
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73460369
86Basal transcription factors_Homo sapiens_hsa030220.73115701
87Pyruvate metabolism_Homo sapiens_hsa006200.73024953
88Retinol metabolism_Homo sapiens_hsa008300.72879541
89Steroid hormone biosynthesis_Homo sapiens_hsa001400.72711630
90Metabolic pathways_Homo sapiens_hsa011000.70421236
91Legionellosis_Homo sapiens_hsa051340.68940549
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.67416523
93Fatty acid metabolism_Homo sapiens_hsa012120.66880802
94Galactose metabolism_Homo sapiens_hsa000520.66783133
95Antigen processing and presentation_Homo sapiens_hsa046120.63974910
96Arginine and proline metabolism_Homo sapiens_hsa003300.63527512
97Herpes simplex infection_Homo sapiens_hsa051680.62924343
98Olfactory transduction_Homo sapiens_hsa047400.61653704
99Steroid biosynthesis_Homo sapiens_hsa001000.61082053
100Huntingtons disease_Homo sapiens_hsa050160.59476427
101Linoleic acid metabolism_Homo sapiens_hsa005910.58575941
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58184408
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58000010
104NOD-like receptor signaling pathway_Homo sapiens_hsa046210.57943711
105Phenylalanine metabolism_Homo sapiens_hsa003600.57350788
106Butanoate metabolism_Homo sapiens_hsa006500.56910659
107Tyrosine metabolism_Homo sapiens_hsa003500.56011904
108p53 signaling pathway_Homo sapiens_hsa041150.55951536
109Fatty acid elongation_Homo sapiens_hsa000620.54191440
110mRNA surveillance pathway_Homo sapiens_hsa030150.54032775
111PPAR signaling pathway_Homo sapiens_hsa033200.53783975
112Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.51716094
113Circadian rhythm_Homo sapiens_hsa047100.50871839
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.50682007
115Other glycan degradation_Homo sapiens_hsa005110.49060813
116Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46507413
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.44309029
118Intestinal immune network for IgA production_Homo sapiens_hsa046720.41959817
119Fructose and mannose metabolism_Homo sapiens_hsa000510.41511702
120ABC transporters_Homo sapiens_hsa020100.39967575
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39902711
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39832200
123Ether lipid metabolism_Homo sapiens_hsa005650.39034453
124Alcoholism_Homo sapiens_hsa050340.38983116
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38847108
126Fat digestion and absorption_Homo sapiens_hsa049750.36575692
127NF-kappa B signaling pathway_Homo sapiens_hsa040640.34818455
128Epstein-Barr virus infection_Homo sapiens_hsa051690.34479296
129Hematopoietic cell lineage_Homo sapiens_hsa046400.33560728
130Oocyte meiosis_Homo sapiens_hsa041140.30705207
131Arachidonic acid metabolism_Homo sapiens_hsa005900.30179667
132Taste transduction_Homo sapiens_hsa047420.30088234
133Nicotine addiction_Homo sapiens_hsa050330.27208302
134Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.25138781

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