TTC30B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)6.33671728
2COPI coating of Golgi vesicle (GO:0048205)6.26555639
3Golgi transport vesicle coating (GO:0048200)6.26555639
4axonemal dynein complex assembly (GO:0070286)5.27111006
5* intraciliary transport (GO:0042073)4.89137001
6axoneme assembly (GO:0035082)4.88382391
7epithelial cilium movement (GO:0003351)4.59228026
8centriole assembly (GO:0098534)4.57175683
9detection of calcium ion (GO:0005513)4.23984824
10primary alcohol catabolic process (GO:0034310)4.14553815
11COPII vesicle coating (GO:0048208)4.14473294
12cilium or flagellum-dependent cell motility (GO:0001539)4.10366138
13embryonic heart tube development (GO:0035050)3.97351642
14terpenoid biosynthetic process (GO:0016114)3.96823861
15regulation of autophagic vacuole assembly (GO:2000785)3.87682709
16retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.82597766
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.80894509
18pyrimidine-containing compound transmembrane transport (GO:0072531)3.78244244
19regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.76203058
20ER overload response (GO:0006983)3.74420485
21endocrine pancreas development (GO:0031018)3.74108470
22glandular epithelial cell differentiation (GO:0002067)3.71469446
23microtubule depolymerization (GO:0007019)3.60749327
24peptide hormone processing (GO:0016486)3.60516579
25diterpenoid biosynthetic process (GO:0016102)3.58204797
26* cell projection assembly (GO:0030031)3.58067704
27maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.52180819
28smoothened signaling pathway (GO:0007224)3.51822316
29isoprenoid biosynthetic process (GO:0008299)3.48532890
30protein maturation by protein folding (GO:0022417)3.46128339
31eye photoreceptor cell differentiation (GO:0001754)3.42829878
32photoreceptor cell differentiation (GO:0046530)3.42829878
33ethanol metabolic process (GO:0006067)3.38237961
34signal peptide processing (GO:0006465)3.32633646
35vesicle coating (GO:0006901)3.32525287
36DNA integration (GO:0015074)3.31529154
37regulation of type B pancreatic cell apoptotic process (GO:2000674)3.30853858
38ventricular system development (GO:0021591)3.30285256
39* cilium organization (GO:0044782)3.27937075
40response to xenobiotic stimulus (GO:0009410)3.26257717
41gonadal mesoderm development (GO:0007506)3.24153106
42vitamin transmembrane transport (GO:0035461)3.23943996
43* cilium assembly (GO:0042384)3.20970569
44GTP biosynthetic process (GO:0006183)3.20108290
45apical protein localization (GO:0045176)3.18772723
46regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.17904314
47sensory perception of smell (GO:0007608)3.16210560
48positive regulation of hormone biosynthetic process (GO:0046886)3.15449189
49positive regulation of smoothened signaling pathway (GO:0045880)3.14711664
50calcium-mediated signaling using intracellular calcium source (GO:0035584)3.12350329
51nucleoside diphosphate phosphorylation (GO:0006165)3.10888375
52determination of bilateral symmetry (GO:0009855)3.10881221
53regulation of vacuole organization (GO:0044088)3.10292380
54centriole replication (GO:0007099)3.08209540
55retinal rod cell development (GO:0046548)3.06611957
56asymmetric protein localization (GO:0008105)3.05591223
57specification of symmetry (GO:0009799)3.05548360
58sperm motility (GO:0030317)3.04639687
59nucleotide transmembrane transport (GO:1901679)3.03952808
60determination of left/right symmetry (GO:0007368)3.02830578
61microtubule polymerization or depolymerization (GO:0031109)3.01222424
62insulin secretion (GO:0030073)2.98947562
63acrosome reaction (GO:0007340)2.98156219
64positive regulation of insulin secretion (GO:0032024)2.97434864
65cilium morphogenesis (GO:0060271)2.96210433
66regulation of glucocorticoid metabolic process (GO:0031943)2.95606346
67negative regulation of hormone metabolic process (GO:0032351)2.94046924
68negative regulation of hormone biosynthetic process (GO:0032353)2.94046924
69synapsis (GO:0007129)2.88871000
70carnitine metabolic process (GO:0009437)2.81529866
71DNA double-strand break processing (GO:0000729)2.75741415
72* organelle assembly (GO:0070925)2.74664760
73cerebellar Purkinje cell layer development (GO:0021680)2.74595180
74regulation of insulin secretion (GO:0050796)2.74469963
75exocrine pancreas development (GO:0031017)2.73455325
76nitric oxide mediated signal transduction (GO:0007263)2.71107298
77androgen biosynthetic process (GO:0006702)2.70848603
78appendage development (GO:0048736)2.69418644
79limb development (GO:0060173)2.69418644
80cholesterol biosynthetic process (GO:0006695)2.69250414
81lateral ventricle development (GO:0021670)2.68300438
82* microtubule-based process (GO:0007017)2.68217735
83protein retention in ER lumen (GO:0006621)2.67637757
84regulation of glucose import in response to insulin stimulus (GO:2001273)2.67265142
85base-excision repair, AP site formation (GO:0006285)2.66115320
86resolution of meiotic recombination intermediates (GO:0000712)2.65124709
87spermatid nucleus differentiation (GO:0007289)2.65091388
88positive regulation of meiosis (GO:0045836)2.63261925
89lateral sprouting from an epithelium (GO:0060601)2.62679914
90magnesium ion transport (GO:0015693)2.62362048
91embryonic camera-type eye development (GO:0031076)2.59747856
92regulation of smoothened signaling pathway (GO:0008589)2.59262635
93one-carbon compound transport (GO:0019755)2.58587437
94intra-Golgi vesicle-mediated transport (GO:0006891)2.57978178
95* cellular component assembly involved in morphogenesis (GO:0010927)2.56964262
96spermatid development (GO:0007286)2.56850120
97regulation of male gonad development (GO:2000018)2.56483934
98regulation of cilium movement (GO:0003352)2.56117399
99organelle disassembly (GO:1903008)2.55923016
100UTP biosynthetic process (GO:0006228)2.54542700
101cytoplasmic microtubule organization (GO:0031122)2.53906582
102motile cilium assembly (GO:0044458)2.53755480
103histone H2A acetylation (GO:0043968)2.53582188
104sequestering of metal ion (GO:0051238)2.52207374
105regulation of oxidative phosphorylation (GO:0002082)2.52066616
106organ formation (GO:0048645)2.51733756
107positive regulation of alcohol biosynthetic process (GO:1902932)2.51728384
108regulation of non-canonical Wnt signaling pathway (GO:2000050)2.51330881
109regulation of peptide hormone secretion (GO:0090276)2.50619681
110retinoic acid metabolic process (GO:0042573)2.50036724
111sperm capacitation (GO:0048240)2.49775925
112guanosine-containing compound biosynthetic process (GO:1901070)2.49543757
113regulation of peptide secretion (GO:0002791)2.48481186
114positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.48422483
115UTP metabolic process (GO:0046051)2.48298416
116left/right axis specification (GO:0070986)2.47673864
117sterol biosynthetic process (GO:0016126)2.46959880
118neuron fate determination (GO:0048664)2.46230670
119regulation of cilium assembly (GO:1902017)2.46112038
120pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.45931694
121male meiosis (GO:0007140)2.45849626
122positive regulation of steroid biosynthetic process (GO:0010893)2.45273454
123positive regulation of meiotic cell cycle (GO:0051446)2.41400436
124microtubule bundle formation (GO:0001578)2.40857733
125protein localization to cilium (GO:0061512)2.40810238
126Leydig cell differentiation (GO:0033327)2.40592213
127protein polyglutamylation (GO:0018095)2.39923555
128response to pheromone (GO:0019236)2.39860998
129positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.39762326
130ribonucleoprotein complex disassembly (GO:0032988)2.38481563
131positive regulation of peptide secretion (GO:0002793)2.37551171
132nonmotile primary cilium assembly (GO:0035058)2.36986239
133regulation of microtubule-based movement (GO:0060632)2.36642485
134positive regulation of peptide hormone secretion (GO:0090277)2.36444341
135tricarboxylic acid cycle (GO:0006099)2.36262098
136L-fucose metabolic process (GO:0042354)2.35652220
137L-fucose catabolic process (GO:0042355)2.35652220
138fucose catabolic process (GO:0019317)2.35652220
139left/right pattern formation (GO:0060972)2.35415115
140aldehyde catabolic process (GO:0046185)2.33717679
141ER to Golgi vesicle-mediated transport (GO:0006888)2.32787128
142binding of sperm to zona pellucida (GO:0007339)2.32409582
143CTP metabolic process (GO:0046036)2.31121651
144CTP biosynthetic process (GO:0006241)2.31121651
145regulation of steroid hormone biosynthetic process (GO:0090030)2.30979773
146mRNA cleavage (GO:0006379)2.29751373
147cell communication involved in cardiac conduction (GO:0086065)2.29603914
148embryonic foregut morphogenesis (GO:0048617)2.29001397
149ethanol oxidation (GO:0006069)2.28242160
150synaptic vesicle docking involved in exocytosis (GO:0016081)2.26836541
151single fertilization (GO:0007338)2.26213444
152response to misfolded protein (GO:0051788)2.26151200
153lactate metabolic process (GO:0006089)2.25280557
154ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.25221550
155* microtubule-based transport (GO:0010970)2.24856210
156establishment of planar polarity (GO:0001736)2.24346598
157cellular ketone body metabolic process (GO:0046950)2.22864240
158sensory perception of chemical stimulus (GO:0007606)2.22349642
159photoreceptor cell maintenance (GO:0045494)2.21552585
160protein localization to Golgi apparatus (GO:0034067)2.20529689
161negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.20166732
162negative regulation of calcium ion transmembrane transport (GO:1903170)2.20166732
163cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.20067795
164regulation of hormone biosynthetic process (GO:0046885)2.19328613
165regulation of synaptic vesicle exocytosis (GO:2000300)2.18145832
166regulation of hormone secretion (GO:0046883)2.17468919
167type B pancreatic cell development (GO:0003323)2.16370940
168* microtubule-based movement (GO:0007018)2.15343036
169inner ear receptor cell development (GO:0060119)2.15314194
170positive regulation of hormone metabolic process (GO:0032352)2.14831917
171retina layer formation (GO:0010842)2.14358454

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.95416778
2EZH2_22144423_ChIP-Seq_EOC_Human4.22773762
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.04221511
4GBX2_23144817_ChIP-Seq_PC3_Human2.74772501
5* PADI4_21655091_ChIP-ChIP_MCF-7_Human2.58148043
6EWS_26573619_Chip-Seq_HEK293_Human2.53539901
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.40467172
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.24902116
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.20455858
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.06584027
11FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.01347291
12PIAS1_25552417_ChIP-Seq_VCAP_Human1.92961677
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.91407895
14ESR1_20079471_ChIP-ChIP_T-47D_Human1.89941956
15GABP_17652178_ChIP-ChIP_JURKAT_Human1.87028485
16ELK1_19687146_ChIP-ChIP_HELA_Human1.81752771
17DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.81508814
18SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.80946200
19FUS_26573619_Chip-Seq_HEK293_Human1.79319390
20PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79084726
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.77622112
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.76744138
23* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.76538318
24KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.73893498
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.71302061
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.70880185
27FOXM1_26456572_ChIP-Seq_MCF-7_Human1.66769173
28SMAD_19615063_ChIP-ChIP_OVARY_Human1.66332777
29SMAD4_21799915_ChIP-Seq_A2780_Human1.65266601
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56951002
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56693872
32SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.55665423
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55361994
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.55348734
35REST_21632747_ChIP-Seq_MESCs_Mouse1.55183420
36SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.53385121
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.53179257
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52795633
39P300_19829295_ChIP-Seq_ESCs_Human1.51758498
40ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49828204
41NR3C1_23031785_ChIP-Seq_PC12_Mouse1.49730011
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.48815999
43ZNF217_24962896_ChIP-Seq_MCF-7_Human1.48410760
44NR3C1_21868756_ChIP-Seq_MCF10A_Human1.47508562
45IRF1_19129219_ChIP-ChIP_H3396_Human1.47401928
46JARID2_20075857_ChIP-Seq_MESCs_Mouse1.47090461
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.45334772
48VDR_22108803_ChIP-Seq_LS180_Human1.43631206
49VDR_23849224_ChIP-Seq_CD4+_Human1.41780051
50ZNF274_21170338_ChIP-Seq_K562_Hela1.41198729
51EST1_17652178_ChIP-ChIP_JURKAT_Human1.40894544
52TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39054764
53EP300_21415370_ChIP-Seq_HL-1_Mouse1.38917640
54HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.38789374
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38388924
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.38002065
57PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37718185
58EZH2_18974828_ChIP-Seq_MESCs_Mouse1.37486966
59RNF2_18974828_ChIP-Seq_MESCs_Mouse1.37486966
60TP53_18474530_ChIP-ChIP_U2OS_Human1.37469196
61EZH2_27304074_Chip-Seq_ESCs_Mouse1.36804306
62BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36757234
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36267597
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.35258850
65PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.35213386
66SUZ12_27294783_Chip-Seq_ESCs_Mouse1.34587084
67CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.33657854
68SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.33218000
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32938723
70STAT3_23295773_ChIP-Seq_U87_Human1.32895654
71NRF2_20460467_ChIP-Seq_MEFs_Mouse1.32879480
72NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.32879480
73EED_16625203_ChIP-ChIP_MESCs_Mouse1.32531320
74DROSHA_22980978_ChIP-Seq_HELA_Human1.31980382
75TCF4_22108803_ChIP-Seq_LS180_Human1.27644451
76DCP1A_22483619_ChIP-Seq_HELA_Human1.27052938
77ARNT_22903824_ChIP-Seq_MCF-7_Human1.26615498
78PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.25710776
79GABP_19822575_ChIP-Seq_HepG2_Human1.25216443
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24634836
81RNF2_27304074_Chip-Seq_ESCs_Mouse1.24107929
82BCAT_22108803_ChIP-Seq_LS180_Human1.24077892
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.23521269
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.23154192
85CREB1_15753290_ChIP-ChIP_HEK293T_Human1.22038222
86JARID2_20064375_ChIP-Seq_MESCs_Mouse1.20558382
87PHF8_20622853_ChIP-Seq_HELA_Human1.20440733
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.20030908
89CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19520273
90AR_21909140_ChIP-Seq_LNCAP_Human1.19435175
91HNFA_21074721_ChIP-Seq_CACO-2_Human1.19259947
92CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.18401401
93* ETV1_20927104_ChIP-Seq_GIST48_Human1.17992505
94AHR_22903824_ChIP-Seq_MCF-7_Human1.17820665
95REST_18959480_ChIP-ChIP_MESCs_Mouse1.17811342
96EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17475361
97NANOG_18555785_Chip-Seq_ESCs_Mouse1.16236492
98TBL1_22424771_ChIP-Seq_293T_Human1.15727415
99FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.15566291
100SOX2_21211035_ChIP-Seq_LN229_Gbm1.15391772
101ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12757972
102* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12748732
103E2F4_17652178_ChIP-ChIP_JURKAT_Human1.12332477
104* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12188858
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11925513
106NFYA_21822215_ChIP-Seq_K562_Human1.11372055
107JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.11309783
108NFYB_21822215_ChIP-Seq_K562_Human1.10851037
109RUNX2_22187159_ChIP-Seq_PCA_Human1.09458360
110MYC_18940864_ChIP-ChIP_HL60_Human1.09240059
111RNF2_27304074_Chip-Seq_NSC_Mouse1.08086518
112GATA4_25053715_ChIP-Seq_YYC3_Human1.07932786
113CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.07325341
114CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.05458797
115IGF1R_20145208_ChIP-Seq_DFB_Human1.04615225
116GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03666339
117KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03590437
118PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03443588
119FOXA1_25552417_ChIP-Seq_VCAP_Human1.03390828
120TCF4_23295773_ChIP-Seq_U87_Human1.02913729
121GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02744585
122BMI1_23680149_ChIP-Seq_NPCS_Mouse1.02545978
123ER_23166858_ChIP-Seq_MCF-7_Human1.02125535
124CBX2_27304074_Chip-Seq_ESCs_Mouse1.01328286
125IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00952079
126CBP_20019798_ChIP-Seq_JUKART_Human1.00952079
127RARB_27405468_Chip-Seq_BRAIN_Mouse1.00698763
128AR_25329375_ChIP-Seq_VCAP_Human1.00618225
129RBPJ_21746931_ChIP-Seq_IB4_Human1.00602724
130TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00142922
131TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99943449
132NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.99783073
133E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98820808
134WT1_19549856_ChIP-ChIP_CCG9911_Human0.98308011
135FLI1_21867929_ChIP-Seq_TH2_Mouse0.97658721
136AR_19668381_ChIP-Seq_PC3_Human0.97371809
137MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96477634
138TAF15_26573619_Chip-Seq_HEK293_Human0.96328640
139YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96306832
140CBX2_22325352_ChIP-Seq_293T-Rex_Human0.96122529
141CHD1_26751641_Chip-Seq_LNCaP_Human0.95745889
142EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95493065
143CDX2_22108803_ChIP-Seq_LS180_Human0.95427222
144YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94798837
145ERG_20517297_ChIP-Seq_VCAP_Human0.94219864
146FOXM1_23109430_ChIP-Seq_U2OS_Human0.93452127
147TRIM28_21343339_ChIP-Seq_HEK293_Human0.93299754
148KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93117021
149OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93067067
150WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92942948
151* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92485454
152AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.91243613
153LXR_22158963_ChIP-Seq_LIVER_Mouse0.90362516
154TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90004064
155* P53_22387025_ChIP-Seq_ESCs_Mouse0.89576886
156FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.88862575
157TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.88342120
158SMAD3_21741376_ChIP-Seq_ESCs_Human0.88296553
159GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.87357017
160TAL1_26923725_Chip-Seq_HPCs_Mouse0.85867779
161GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.85802119
162FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.85715158

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy4.02930321
2MP0005248_abnormal_Harderian_gland3.69183128
3MP0002909_abnormal_adrenal_gland3.64442057
4MP0000013_abnormal_adipose_tissue3.49084342
5MP0003183_abnormal_peptide_metabolism3.27452846
6MP0003283_abnormal_digestive_organ3.17757835
7MP0002837_dystrophic_cardiac_calcinosis3.02807582
8MP0004043_abnormal_pH_regulation2.91165248
9MP0009780_abnormal_chondrocyte_physiolo2.90919333
10MP0003195_calcinosis2.77096904
11MP0001984_abnormal_olfaction2.75097625
12MP0010030_abnormal_orbit_morphology2.72907621
13MP0000537_abnormal_urethra_morphology2.70178378
14MP0002877_abnormal_melanocyte_morpholog2.66994640
15MP0008875_abnormal_xenobiotic_pharmacok2.56720561
16MP0002132_abnormal_respiratory_system2.55731781
17MP0010386_abnormal_urinary_bladder2.53076263
18MP0002139_abnormal_hepatobiliary_system2.42662632
19MP0000566_synostosis2.33279520
20MP0000383_abnormal_hair_follicle2.28178339
21MP0003890_abnormal_embryonic-extraembry2.25914312
22MP0010678_abnormal_skin_adnexa2.18774252
23MP0005646_abnormal_pituitary_gland2.15496329
24MP0002233_abnormal_nose_morphology2.09543562
25MP0002102_abnormal_ear_morphology2.07993344
26MP0001944_abnormal_pancreas_morphology2.04980106
27MP0010234_abnormal_vibrissa_follicle2.03308998
28MP0004270_analgesia2.00606589
29MP0005379_endocrine/exocrine_gland_phen1.97233550
30MP0002282_abnormal_trachea_morphology1.96053343
31MP0001529_abnormal_vocalization1.94918500
32MP0005367_renal/urinary_system_phenotyp1.93712703
33MP0000516_abnormal_urinary_system1.93712703
34MP0004133_heterotaxia1.93169339
35MP0002928_abnormal_bile_duct1.90794481
36MP0001502_abnormal_circadian_rhythm1.87297789
37MP0006072_abnormal_retinal_apoptosis1.84446080
38MP0003315_abnormal_perineum_morphology1.83792777
39MP0003937_abnormal_limbs/digits/tail_de1.80847831
40MP0002693_abnormal_pancreas_physiology1.77875114
41MP0002653_abnormal_ependyma_morphology1.76514492
42MP0000678_abnormal_parathyroid_gland1.69997396
43MP0000003_abnormal_adipose_tissue1.68064982
44MP0005220_abnormal_exocrine_pancreas1.61386434
45MP0003121_genomic_imprinting1.60146456
46MP0002078_abnormal_glucose_homeostasis1.56160438
47MP0004885_abnormal_endolymph1.50466108
48MP0005365_abnormal_bile_salt1.50354340
49MP0005551_abnormal_eye_electrophysiolog1.50252013
50MP0005623_abnormal_meninges_morphology1.49168811
51MP0001929_abnormal_gametogenesis1.45422141
52MP0005645_abnormal_hypothalamus_physiol1.41590375
53MP0003119_abnormal_digestive_system1.39772190
54MP0005670_abnormal_white_adipose1.38357937
55MP0002734_abnormal_mechanical_nocicepti1.36737545
56MP0004215_abnormal_myocardial_fiber1.36731097
57MP0003122_maternal_imprinting1.36679185
58MP0003635_abnormal_synaptic_transmissio1.36251253
59MP0003880_abnormal_central_pattern1.33930200
60MP0002876_abnormal_thyroid_physiology1.32506637
61MP0002234_abnormal_pharynx_morphology1.32328846
62MP0001346_abnormal_lacrimal_gland1.31722439
63MP0005187_abnormal_penis_morphology1.31682055
64MP0002249_abnormal_larynx_morphology1.30442804
65MP0002277_abnormal_respiratory_mucosa1.30335110
66MP0001293_anophthalmia1.30061917
67MP0001485_abnormal_pinna_reflex1.29994916
68MP0005171_absent_coat_pigmentation1.27038571
69MP0005253_abnormal_eye_physiology1.26862899
70MP0000465_gastrointestinal_hemorrhage1.24364526
71MP0003698_abnormal_male_reproductive1.24000284
72MP0004859_abnormal_synaptic_plasticity1.23149522
73MP0003755_abnormal_palate_morphology1.20820795
74MP0000462_abnormal_digestive_system1.18560754
75MP0001765_abnormal_ion_homeostasis1.17675209
76MP0008058_abnormal_DNA_repair1.17627833
77MP0000538_abnormal_urinary_bladder1.15324610
78MP0001188_hyperpigmentation1.13845508
79MP0010094_abnormal_chromosome_stability1.12910970
80MP0003718_maternal_effect1.12667593
81MP0002295_abnormal_pulmonary_circulatio1.12132881
82MP0005391_vision/eye_phenotype1.11615972
83MP0000631_abnormal_neuroendocrine_gland1.09075429
84MP0002063_abnormal_learning/memory/cond1.08210492
85MP0002084_abnormal_developmental_patter1.08149405
86MP0002572_abnormal_emotion/affect_behav1.05159589
87MP0002229_neurodegeneration1.04302112
88MP0003953_abnormal_hormone_level1.04300223
89MP0002896_abnormal_bone_mineralization1.03055693
90MP0001145_abnormal_male_reproductive1.02960260
91MP0003634_abnormal_glial_cell1.02723969
92MP0002210_abnormal_sex_determination1.02514325
93MP0002272_abnormal_nervous_system1.00313371
94MP0005058_abnormal_lysosome_morphology0.99755848
95MP0002064_seizures0.98766490
96MP0005535_abnormal_body_temperature0.97898739
97MP0000653_abnormal_sex_gland0.96511380
98MP0001664_abnormal_digestion0.96074816
99MP0003868_abnormal_feces_composition0.95134777
100MP0005375_adipose_tissue_phenotype0.94889622
101MP0002098_abnormal_vibrissa_morphology0.94802074
102MP0001764_abnormal_homeostasis0.94500864
103MP0000778_abnormal_nervous_system0.94092742
104MP0008789_abnormal_olfactory_epithelium0.93545651
105MP0002092_abnormal_eye_morphology0.93201494
106MP0004019_abnormal_vitamin_homeostasis0.92704463
107MP0002557_abnormal_social/conspecific_i0.92207395
108MP0009697_abnormal_copulation0.91036060
109MP0002882_abnormal_neuron_morphology0.90982793
110MP0003806_abnormal_nucleotide_metabolis0.89983238
111MP0000762_abnormal_tongue_morphology0.89122768
112MP0000427_abnormal_hair_cycle0.88566418
113MP0009703_decreased_birth_body0.87751687
114MP0003942_abnormal_urinary_system0.87242389
115MP0003693_abnormal_embryo_hatching0.86475557
116MP0002085_abnormal_embryonic_tissue0.86463935
117MP0000955_abnormal_spinal_cord0.86245732
118MP0000681_abnormal_thyroid_gland0.86120671
119MP0002160_abnormal_reproductive_system0.85626960
120MP0000647_abnormal_sebaceous_gland0.85477838
121MP0001286_abnormal_eye_development0.85352749
122MP0003136_yellow_coat_color0.85331226
123MP0004085_abnormal_heartbeat0.83875982
124MP0001486_abnormal_startle_reflex0.83112941
125MP0003861_abnormal_nervous_system0.81059465
126MP0004264_abnormal_extraembryonic_tissu0.80543128
127MP0002735_abnormal_chemical_nociception0.79925943
128MP0002116_abnormal_craniofacial_bone0.79807819
129MP0003385_abnormal_body_wall0.79600589
130MP0003959_abnormal_lean_body0.78502730
131MP0003936_abnormal_reproductive_system0.78283659
132MP0001727_abnormal_embryo_implantation0.78178702
133MP0002127_abnormal_cardiovascular_syste0.78101190
134MP0005410_abnormal_fertilization0.77563435
135MP0005636_abnormal_mineral_homeostasis0.77281877
136MP0005395_other_phenotype0.77172164
137MP0005666_abnormal_adipose_tissue0.76791771
138MP0005448_abnormal_energy_balance0.76111661
139MP0001324_abnormal_eye_pigmentation0.75792817
140MP0002938_white_spotting0.75691438
141MP0003252_abnormal_bile_duct0.75554273
142MP0002118_abnormal_lipid_homeostasis0.75478268
143MP0006276_abnormal_autonomic_nervous0.75124597
144MP0000049_abnormal_middle_ear0.75118624
145MP0003938_abnormal_ear_development0.74675237
146MP0003879_abnormal_hair_cell0.74478908
147MP0000534_abnormal_ureter_morphology0.74421064
148MP0003935_abnormal_craniofacial_develop0.74298360
149MP0003123_paternal_imprinting0.72642765
150MP0008932_abnormal_embryonic_tissue0.72626541
151MP0003633_abnormal_nervous_system0.72134278
152MP0009745_abnormal_behavioral_response0.71568219
153MP0002184_abnormal_innervation0.71060529
154MP0002161_abnormal_fertility/fecundity0.71014975
155MP0002111_abnormal_tail_morphology0.70698449
156MP0009643_abnormal_urine_homeostasis0.70684066
157MP0005085_abnormal_gallbladder_physiolo0.70662980
158MP0009053_abnormal_anal_canal0.70560715
159MP0005394_taste/olfaction_phenotype0.70464870
160MP0005499_abnormal_olfactory_system0.70464870
161MP0010368_abnormal_lymphatic_system0.70345031
162MP0001270_distended_abdomen0.70333723
163MP0000026_abnormal_inner_ear0.70033241
164MP0009250_abnormal_appendicular_skeleto0.69552267
165MP0002638_abnormal_pupillary_reflex0.68718935
166MP0005389_reproductive_system_phenotype0.68524255
167MP0003329_amyloid_beta_deposits0.68513881
168MP0002067_abnormal_sensory_capabilities0.68274007
169MP0008995_early_reproductive_senescence0.67518709
170MP0004130_abnormal_muscle_cell0.67479134
171MP0002109_abnormal_limb_morphology0.66103330
172MP0000639_abnormal_adrenal_gland0.64719853
173MP0002009_preneoplasia0.63919231
174MP0001177_atelectasis0.62568774
175MP0002697_abnormal_eye_size0.60737087

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)6.76723503
2Abnormal ciliary motility (HP:0012262)6.70019442
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.84615403
4Chronic bronchitis (HP:0004469)5.52983062
5Rhinitis (HP:0012384)5.35801445
6Nasal polyposis (HP:0100582)4.70088013
7Abnormal respiratory epithelium morphology (HP:0012253)4.54582768
8Abnormal respiratory motile cilium morphology (HP:0005938)4.54582768
9Recurrent sinusitis (HP:0011108)3.80523726
10Abnormality of the nasal mucosa (HP:0000433)3.73093087
11Hypoglycemic coma (HP:0001325)3.62614265
12Hyperinsulinemic hypoglycemia (HP:0000825)3.51908298
13Hypoglycemic seizures (HP:0002173)3.42486839
14Pancreatic fibrosis (HP:0100732)3.41744229
15Menstrual irregularities (HP:0000858)3.26352967
16Gait imbalance (HP:0002141)3.26274132
17Dynein arm defect of respiratory motile cilia (HP:0012255)3.23396993
18Absent/shortened dynein arms (HP:0200106)3.23396993
19Occipital encephalocele (HP:0002085)3.21036769
20Bronchiectasis (HP:0002110)3.18700185
21True hermaphroditism (HP:0010459)3.16209087
22Dysostosis multiplex (HP:0000943)3.11607125
23Congenital primary aphakia (HP:0007707)3.11539257
24Medial flaring of the eyebrow (HP:0010747)3.10954201
25Ketoacidosis (HP:0001993)3.08959506
26Chronic sinusitis (HP:0011109)3.01688069
27Central scotoma (HP:0000603)3.00961946
28Decreased circulating renin level (HP:0003351)2.89149499
29Male infertility (HP:0003251)2.87883231
30Nephrogenic diabetes insipidus (HP:0009806)2.78240367
31Recurrent otitis media (HP:0000403)2.77356885
32Symptomatic seizures (HP:0011145)2.76312663
33Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.75905931
34Pheochromocytoma (HP:0002666)2.70090645
35Cystic liver disease (HP:0006706)2.66776575
36Neuroendocrine neoplasm (HP:0100634)2.64321714
37Abnormality of midbrain morphology (HP:0002418)2.63032199
38Molar tooth sign on MRI (HP:0002419)2.63032199
39Abnormality of macular pigmentation (HP:0008002)2.52109951
40Genital tract atresia (HP:0001827)2.49815253
41Pancreatic cysts (HP:0001737)2.49719299
42Agitation (HP:0000713)2.48911345
43Vaginal atresia (HP:0000148)2.48178672
44Male pseudohermaphroditism (HP:0000037)2.39793806
45Bifid tongue (HP:0010297)2.37595306
46Hyperactive renin-angiotensin system (HP:0000841)2.34522747
47Poor coordination (HP:0002370)2.31052120
48Hyperglycemia (HP:0003074)2.30663309
49Abnormality of the renal medulla (HP:0100957)2.25912884
50Short nail (HP:0001799)2.24711389
51Ketosis (HP:0001946)2.24552038
52Generalized aminoaciduria (HP:0002909)2.22868605
53Insulin-resistant diabetes mellitus (HP:0000831)2.20930288
54Global brain atrophy (HP:0002283)2.19959918
55Hyperkalemia (HP:0002153)2.18903189
56Scotoma (HP:0000575)2.18464503
57Abnormality of the intrinsic pathway (HP:0010989)2.11454194
58Atelectasis (HP:0100750)2.11385857
59Furrowed tongue (HP:0000221)2.07189617
60Mucopolysacchariduria (HP:0008155)2.06864329
61Urinary glycosaminoglycan excretion (HP:0003541)2.06864329
62Gout (HP:0001997)2.06070335
63Chronic hepatic failure (HP:0100626)2.05534960
64Facial cleft (HP:0002006)2.04796023
65Hypokalemia (HP:0002900)2.04541636
66Abnormality of renin-angiotensin system (HP:0000847)2.02176413
67Hypothermia (HP:0002045)2.01431619
68Dry hair (HP:0011359)2.01415532
69Abnormality of mucopolysaccharide metabolism (HP:0011020)2.00454577
70Abnormality of polysaccharide metabolism (HP:0011012)2.00454577
71Abnormality of glycosaminoglycan metabolism (HP:0004371)2.00454577
72Tubulointerstitial abnormality (HP:0001969)1.97496940
73Renal salt wasting (HP:0000127)1.96538707
74Abnormality of aromatic amino acid family metabolism (HP:0004338)1.96175159
75Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.95431901
76Bronchitis (HP:0012387)1.94573322
77Abnormal pancreas size (HP:0012094)1.94233491
78Nephronophthisis (HP:0000090)1.91712957
79Focal motor seizures (HP:0011153)1.89001330
80Aplasia/Hypoplasia of the lens (HP:0008063)1.88824673
81Left ventricular hypertrophy (HP:0001712)1.88213284
82Progressive neurologic deterioration (HP:0002344)1.87087192
83Sex reversal (HP:0012245)1.86635454
84Abnormal sex determination (HP:0012244)1.86635454
85Abnormality of potassium homeostasis (HP:0011042)1.86154232
86Anencephaly (HP:0002323)1.85403393
87Renal dysplasia (HP:0000110)1.85366831
88Aplasia/Hypoplasia of the tongue (HP:0010295)1.84705990
89Labial hypoplasia (HP:0000066)1.84021615
90Palpitations (HP:0001962)1.82880754
91Abnormal biliary tract physiology (HP:0012439)1.82729870
92Bile duct proliferation (HP:0001408)1.82729870
93Back pain (HP:0003418)1.81600739
94Chronic otitis media (HP:0000389)1.80331157
95Decreased lacrimation (HP:0000633)1.79592922
96Abnormality of dicarboxylic acid metabolism (HP:0010995)1.79528160
97Dicarboxylic aciduria (HP:0003215)1.79528160
98Hypoplastic labia majora (HP:0000059)1.79422056
99Tubular atrophy (HP:0000092)1.79236823
100Congenital hepatic fibrosis (HP:0002612)1.79145245
101Abnormality of dentin (HP:0010299)1.78515012
102Visual hallucinations (HP:0002367)1.78313006
103Mesomelia (HP:0003027)1.77493337
104Preaxial hand polydactyly (HP:0001177)1.77252892
105Epileptic encephalopathy (HP:0200134)1.75212072
106Unilateral renal agenesis (HP:0000122)1.74241955
107Neurofibrillary tangles (HP:0002185)1.73321131
108Abnormal drinking behavior (HP:0030082)1.73266894
109Polydipsia (HP:0001959)1.73266894
110Hyperglycinemia (HP:0002154)1.72372550
111Abnormal auditory evoked potentials (HP:0006958)1.71710856
112Tubulointerstitial nephritis (HP:0001970)1.71115431
113Postaxial hand polydactyly (HP:0001162)1.71022200
114Median cleft lip (HP:0000161)1.70530072
115Restlessness (HP:0000711)1.70242081
116Infertility (HP:0000789)1.69555520
117Retinal dysplasia (HP:0007973)1.68673306
118Abnormality of the fovea (HP:0000493)1.67906372
119Congenital sensorineural hearing impairment (HP:0008527)1.67455206
120Sclerocornea (HP:0000647)1.65598297
121Fibular hypoplasia (HP:0003038)1.65218103
122Abnormality of the frontal sinuses (HP:0002687)1.64999905
123Papillary thyroid carcinoma (HP:0002895)1.64348023
124Anxiety (HP:0000739)1.62985755
125Syncope (HP:0001279)1.61951115
126Abnormality of calcium-phosphate metabolism (HP:0100530)1.60573622
127Postaxial foot polydactyly (HP:0001830)1.60063214
128Medulloblastoma (HP:0002885)1.57391949
129Oculomotor apraxia (HP:0000657)1.55550005
130Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.51778516
131Abnormality of permanent molar morphology (HP:0011071)1.50925771
132Abnormality of the dental root (HP:0006486)1.50925771
133Taurodontia (HP:0000679)1.50925771
134Bell-shaped thorax (HP:0001591)1.48907909
135Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.46374360
136Broad foot (HP:0001769)1.40725945
137Multicystic kidney dysplasia (HP:0000003)1.37674206
138Aganglionic megacolon (HP:0002251)1.36815406
139Aplasia/Hypoplasia of the fibula (HP:0006492)1.36382199
140Aplasia/hypoplasia of the uterus (HP:0008684)1.33047752
141Abnormality of molar morphology (HP:0011070)1.32971694
142Abnormality of molar (HP:0011077)1.32971694
143Facial hemangioma (HP:0000329)1.31000093
144Narrow forehead (HP:0000341)1.30968195
145Reduced antithrombin III activity (HP:0001976)1.30492531
146Abnormality of the dental pulp (HP:0006479)1.30096443
147Decreased testicular size (HP:0008734)1.29876145
148Prominent nasal bridge (HP:0000426)1.29751779
149Microvesicular hepatic steatosis (HP:0001414)1.26666608
150Nephropathy (HP:0000112)1.26634982
151Hypoplastic pelvis (HP:0008839)1.26051459
152Stage 5 chronic kidney disease (HP:0003774)1.25690230
153Absent frontal sinuses (HP:0002688)1.24449673
154Abnormality of the renal cortex (HP:0011035)1.22989875
155Broad distal phalanx of finger (HP:0009836)1.22656304
156Short ribs (HP:0000773)1.21814759
157Retinitis pigmentosa (HP:0000510)1.21657206
158Self-mutilation (HP:0000742)1.20780038

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.35218109
2INSRR2.94182610
3PRKD32.91542367
4MST42.84528055
5SRPK12.67029156
6PASK2.66002606
7FRK2.52850020
8CSNK1G32.36460073
9CSNK1G12.20659537
10MAP3K22.17973758
11ARAF2.16873283
12TRIM282.16381671
13CSNK1G22.13965700
14TLK12.03182327
15WNK42.02694040
16ZAK1.87831588
17EPHA21.85678999
18GRK71.77758034
19TTK1.76937474
20ERBB31.74820141
21IRAK11.62351845
22MAP4K21.58707229
23STK161.57514757
24PNCK1.56463102
25PLK41.54187593
26PLK21.50532039
27PHKG11.49636465
28PHKG21.49636465
29NTRK31.47206881
30BCKDK1.43982778
31CASK1.38883945
32TSSK61.37817613
33WNK31.35446454
34PLK11.35414049
35PAK31.31599092
36EPHA41.31392781
37CCNB11.31059810
38HIPK21.30767964
39LMTK21.29113066
40DYRK31.22447353
41BUB11.18392390
42MARK11.16772365
43NTRK21.16580677
44BRD41.15412270
45AKT31.14183605
46SGK2231.12978998
47SGK4941.12978998
48MAPK131.10875338
49CDC42BPA1.09316316
50NEK91.00263446
51PRPF4B0.97705731
52MAP2K70.96110370
53BRAF0.94408165
54PBK0.92296705
55SCYL20.91980531
56NLK0.90900089
57RPS6KA50.89920703
58RPS6KA40.89545421
59MUSK0.87890185
60STK390.87335298
61MAP3K90.87076207
62PRKCH0.86172198
63CAMK1G0.86082435
64BMPR20.84379444
65MKNK10.83649804
66NEK20.82898723
67PRKCE0.82032901
68CAMKK20.81761334
69SIK10.81382592
70NME10.81171185
71AURKA0.80148011
72STK38L0.80082047
73GRK10.79696429
74PRKCG0.77610833
75TNIK0.77338834
76CAMK2D0.77171095
77DAPK20.76967906
78KSR20.76965364
79MINK10.76209524
80CAMK2B0.75670393
81MAP3K40.74652047
82FGFR20.73406377
83LIMK10.70786933
84BRSK20.70533638
85PAK40.68277381
86MARK30.67107965
87MAPKAPK50.66436404
88AKT20.66327565
89PIK3CG0.65782087
90CSNK1A10.65415505
91WEE10.65195173
92NTRK10.64819900
93SGK20.64018962
94FES0.63589501
95WNK10.62696355
96EPHA30.62147021
97MAP3K10.61832242
98RPS6KA20.61742687
99MAPKAPK30.60301537
100CAMK2A0.60076485
101CDK50.60052088
102BCR0.59873957
103PLK30.59432924
104GRK50.59150195
105PTK60.58858770
106PRKD20.58697027
107PINK10.58555275
108CHEK20.57742689
109OXSR10.57693792
110AURKB0.57452166
111ATM0.57157054
112PTK2B0.56459786
113PDGFRA0.56455800
114PTK20.55690373
115FER0.52713231
116MAP3K130.51552723
117MKNK20.51548969
118TESK10.51098597
119CDK60.50900668
120ATR0.49215622
121DYRK1B0.49073494
122EPHB10.47565724
123DYRK20.47197493
124PAK60.44542133
125PDK40.44347569
126PDK30.44347569
127PRKAA10.43918994
128CAMK2G0.43103914
129STK240.42634392
130PRKACG0.42437326
131ADRBK10.42346110
132PRKCI0.42325777
133NEK60.42315580
134EPHB20.42093457
135MOS0.41752331
136CSNK1A1L0.41384262
137UHMK10.41280503
138MARK20.41267075
139VRK10.41108201
140OBSCN0.40695789
141MYLK0.39920723
142ERBB20.39478286
143STK380.39212518
144MAP2K40.38283661
145KSR10.37957625
146PRKACA0.36950681
147EIF2AK10.36915170
148CDK30.36572892
149MAP2K10.36246065
150PRKAA20.35507285
151CSNK1D0.35290807
152EGFR0.33941360
153BMPR1B0.32614633
154PKN20.32218530
155LATS10.31975583
156CDK140.31306159
157MAP3K100.28009751
158CSNK2A10.27927269
159MAP3K50.27838742
160CSNK1E0.25499789
161CDK90.24780515
162DYRK1A0.24672726
163TGFBR10.20937896
164PKN10.20735235
165RPS6KB10.20345219
166MAP3K30.19872871

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.92476930
2Protein export_Homo sapiens_hsa030603.78855213
3Steroid biosynthesis_Homo sapiens_hsa001003.03545268
4Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.94290573
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.92330468
6Sulfur metabolism_Homo sapiens_hsa009202.68432861
7Insulin secretion_Homo sapiens_hsa049112.55064410
8Butanoate metabolism_Homo sapiens_hsa006502.47631668
9Chemical carcinogenesis_Homo sapiens_hsa052042.35263244
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26357807
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.25698554
12Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.10042539
13Fanconi anemia pathway_Homo sapiens_hsa034602.00717621
14Olfactory transduction_Homo sapiens_hsa047401.97932668
15Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.93687199
16Basal cell carcinoma_Homo sapiens_hsa052171.87388395
17Synaptic vesicle cycle_Homo sapiens_hsa047211.84082108
18Vibrio cholerae infection_Homo sapiens_hsa051101.79633851
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.79293242
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.73214936
21Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.69120419
22Propanoate metabolism_Homo sapiens_hsa006401.68646844
23Amphetamine addiction_Homo sapiens_hsa050311.63809937
24Glutathione metabolism_Homo sapiens_hsa004801.63239734
25Cocaine addiction_Homo sapiens_hsa050301.63191107
26Collecting duct acid secretion_Homo sapiens_hsa049661.61880895
27Other glycan degradation_Homo sapiens_hsa005111.49855572
28Basal transcription factors_Homo sapiens_hsa030221.42241810
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.40390586
30Taste transduction_Homo sapiens_hsa047421.39434823
31Circadian entrainment_Homo sapiens_hsa047131.38109307
32Phototransduction_Homo sapiens_hsa047441.36162237
33Alcoholism_Homo sapiens_hsa050341.34775450
34Retinol metabolism_Homo sapiens_hsa008301.34119188
35Base excision repair_Homo sapiens_hsa034101.32261989
36Systemic lupus erythematosus_Homo sapiens_hsa053221.31204726
37Fatty acid degradation_Homo sapiens_hsa000711.30943252
38GABAergic synapse_Homo sapiens_hsa047271.26001706
39Thyroid hormone synthesis_Homo sapiens_hsa049181.24681649
40Nucleotide excision repair_Homo sapiens_hsa034201.24406489
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.20872870
42Steroid hormone biosynthesis_Homo sapiens_hsa001401.18330417
43Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.17077824
44Fatty acid metabolism_Homo sapiens_hsa012121.16719397
45Circadian rhythm_Homo sapiens_hsa047101.15225271
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.14408119
47Dopaminergic synapse_Homo sapiens_hsa047281.13856001
48Pyruvate metabolism_Homo sapiens_hsa006201.10407908
49Glucagon signaling pathway_Homo sapiens_hsa049221.07890946
50Tryptophan metabolism_Homo sapiens_hsa003801.06467899
51Fatty acid elongation_Homo sapiens_hsa000621.04078708
52Caffeine metabolism_Homo sapiens_hsa002321.02732237
53Mismatch repair_Homo sapiens_hsa034301.02421800
54Pentose and glucuronate interconversions_Homo sapiens_hsa000401.00521291
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98844460
56Morphine addiction_Homo sapiens_hsa050320.97502380
57Long-term potentiation_Homo sapiens_hsa047200.97208632
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.96703113
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96437421
60Selenocompound metabolism_Homo sapiens_hsa004500.95678134
61Hippo signaling pathway_Homo sapiens_hsa043900.95228472
62Lysosome_Homo sapiens_hsa041420.95065126
63Carbohydrate digestion and absorption_Homo sapiens_hsa049730.95005323
64Type II diabetes mellitus_Homo sapiens_hsa049300.94764271
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.94412089
66mRNA surveillance pathway_Homo sapiens_hsa030150.93906000
67Regulation of autophagy_Homo sapiens_hsa041400.93430692
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.91798484
69Cholinergic synapse_Homo sapiens_hsa047250.91534554
70RNA transport_Homo sapiens_hsa030130.90094493
71Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.90000205
72Histidine metabolism_Homo sapiens_hsa003400.89959366
73Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.89651181
74Oxidative phosphorylation_Homo sapiens_hsa001900.89636905
75Oocyte meiosis_Homo sapiens_hsa041140.89475833
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.89212667
77Glutamatergic synapse_Homo sapiens_hsa047240.86809676
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86297451
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.85762470
80Nicotine addiction_Homo sapiens_hsa050330.85461794
81Huntingtons disease_Homo sapiens_hsa050160.84407996
82Spliceosome_Homo sapiens_hsa030400.84400622
83Gastric acid secretion_Homo sapiens_hsa049710.83082102
84Serotonergic synapse_Homo sapiens_hsa047260.82167408
85N-Glycan biosynthesis_Homo sapiens_hsa005100.81912082
86Ovarian steroidogenesis_Homo sapiens_hsa049130.80644728
87Peroxisome_Homo sapiens_hsa041460.78657139
88Homologous recombination_Homo sapiens_hsa034400.77834020
89Non-homologous end-joining_Homo sapiens_hsa034500.74243606
90Metabolic pathways_Homo sapiens_hsa011000.74041636
91Alzheimers disease_Homo sapiens_hsa050100.73933886
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73269014
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72901628
94TGF-beta signaling pathway_Homo sapiens_hsa043500.71130835
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.70501311
96Cell cycle_Homo sapiens_hsa041100.70184896
97Wnt signaling pathway_Homo sapiens_hsa043100.69871972
98PPAR signaling pathway_Homo sapiens_hsa033200.69521355
99cAMP signaling pathway_Homo sapiens_hsa040240.69181431
100Tight junction_Homo sapiens_hsa045300.68127199
101Proteasome_Homo sapiens_hsa030500.67805871
102RNA degradation_Homo sapiens_hsa030180.67780320
103Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.66030398
104Prion diseases_Homo sapiens_hsa050200.65383858
105Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.64971344
106Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64705635
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64416591
108Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63695795
109Renin secretion_Homo sapiens_hsa049240.63191517
110Phenylalanine metabolism_Homo sapiens_hsa003600.62280472
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.61993334
112Estrogen signaling pathway_Homo sapiens_hsa049150.60532911
113Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.60459091
114Insulin resistance_Homo sapiens_hsa049310.58980215
115Parkinsons disease_Homo sapiens_hsa050120.58831515
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58259834
117Pancreatic secretion_Homo sapiens_hsa049720.57925884
118Sphingolipid metabolism_Homo sapiens_hsa006000.57184944
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55497900
120Cardiac muscle contraction_Homo sapiens_hsa042600.55418533
121Purine metabolism_Homo sapiens_hsa002300.54506687
122ABC transporters_Homo sapiens_hsa020100.54435699
123Melanogenesis_Homo sapiens_hsa049160.53949821
124beta-Alanine metabolism_Homo sapiens_hsa004100.53824216
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53257164
126Salivary secretion_Homo sapiens_hsa049700.53162849
127RNA polymerase_Homo sapiens_hsa030200.52985654
128Drug metabolism - other enzymes_Homo sapiens_hsa009830.51950657
129Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51462985
130GnRH signaling pathway_Homo sapiens_hsa049120.50639829
131Calcium signaling pathway_Homo sapiens_hsa040200.50590769
132Tyrosine metabolism_Homo sapiens_hsa003500.50290370
133Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49407452
134Sulfur relay system_Homo sapiens_hsa041220.48804226
135Bile secretion_Homo sapiens_hsa049760.48582166
136Starch and sucrose metabolism_Homo sapiens_hsa005000.47960808
137Biosynthesis of amino acids_Homo sapiens_hsa012300.47058734
138Phagosome_Homo sapiens_hsa041450.46239980
139Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45566249
140Primary bile acid biosynthesis_Homo sapiens_hsa001200.45191093
141DNA replication_Homo sapiens_hsa030300.44183761
142Glycerophospholipid metabolism_Homo sapiens_hsa005640.43955111
143Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43896336
144Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43870910
145Hedgehog signaling pathway_Homo sapiens_hsa043400.43523267
146Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42267121
147Galactose metabolism_Homo sapiens_hsa000520.42243979
148AMPK signaling pathway_Homo sapiens_hsa041520.41638568
149Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.40896116
150Carbon metabolism_Homo sapiens_hsa012000.40626055
151Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40237928
152Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.40200332
1532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39644934
154Insulin signaling pathway_Homo sapiens_hsa049100.39462670
155Asthma_Homo sapiens_hsa053100.39288633
156Oxytocin signaling pathway_Homo sapiens_hsa049210.38457774
157Pyrimidine metabolism_Homo sapiens_hsa002400.37703674
158p53 signaling pathway_Homo sapiens_hsa041150.37267224
159Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35480629

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