TRPT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)7.47269024
2ATP synthesis coupled proton transport (GO:0015986)7.38349840
3energy coupled proton transport, down electrochemical gradient (GO:0015985)7.38349840
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.21377996
5respiratory electron transport chain (GO:0022904)5.66737908
6electron transport chain (GO:0022900)5.50899164
7viral transcription (GO:0019083)4.10359557
8tricarboxylic acid cycle (GO:0006099)4.07158374
9ATP biosynthetic process (GO:0006754)3.89230639
10pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.88510330
11cytochrome complex assembly (GO:0017004)3.87702187
12metallo-sulfur cluster assembly (GO:0031163)3.87480953
13iron-sulfur cluster assembly (GO:0016226)3.87480953
14translational termination (GO:0006415)3.86420264
15chaperone-mediated protein transport (GO:0072321)3.84730901
16negative regulation of protein localization to cell surface (GO:2000009)3.80706545
17GTP biosynthetic process (GO:0006183)3.77050899
18NADH metabolic process (GO:0006734)3.76837451
19ATP hydrolysis coupled proton transport (GO:0015991)3.75947222
20energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.75947222
21SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.74410172
22regulation of mitochondrial translation (GO:0070129)3.74203005
23ribosomal small subunit assembly (GO:0000028)3.66011086
24protein complex biogenesis (GO:0070271)3.65313935
25cotranslational protein targeting to membrane (GO:0006613)3.65024365
26protein targeting to ER (GO:0045047)3.63999805
27neuronal action potential propagation (GO:0019227)3.61802707
28hydrogen ion transmembrane transport (GO:1902600)3.55646051
29protein localization to endoplasmic reticulum (GO:0070972)3.55254488
30pyrimidine nucleotide catabolic process (GO:0006244)3.54341913
31base-excision repair, AP site formation (GO:0006285)3.54258659
32purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.52276239
33translational elongation (GO:0006414)3.51742995
34purine nucleoside triphosphate biosynthetic process (GO:0009145)3.51367044
35oxidative phosphorylation (GO:0006119)3.49473591
36protein targeting to mitochondrion (GO:0006626)3.48961199
37establishment of protein localization to endoplasmic reticulum (GO:0072599)3.48122061
38cardiac myofibril assembly (GO:0055003)3.43596890
39mitochondrial respiratory chain complex I assembly (GO:0032981)3.42085862
40NADH dehydrogenase complex assembly (GO:0010257)3.42085862
41mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.42085862
42respiratory chain complex IV assembly (GO:0008535)3.41800444
43sequestering of actin monomers (GO:0042989)3.41565523
44ubiquinone biosynthetic process (GO:0006744)3.40283297
45central nervous system myelination (GO:0022010)3.40072708
46axon ensheathment in central nervous system (GO:0032291)3.40072708
47deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.38075336
48regulation of oxidative phosphorylation (GO:0002082)3.37932616
49negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.35821229
50actin-myosin filament sliding (GO:0033275)3.34172772
51muscle filament sliding (GO:0030049)3.34172772
52mitochondrial respiratory chain complex assembly (GO:0033108)3.32710162
53regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.29355234
54establishment of protein localization to mitochondrion (GO:0072655)3.28141400
55sarcomere organization (GO:0045214)3.27295144
56positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.26664426
57regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.26410226
58sarcoplasmic reticulum calcium ion transport (GO:0070296)3.24699873
59ribosomal small subunit biogenesis (GO:0042274)3.23271459
60regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.23177875
61peptidyl-histidine modification (GO:0018202)3.22783069
62presynaptic membrane assembly (GO:0097105)3.22116053
63regulation of cilium movement (GO:0003352)3.19569994
64viral life cycle (GO:0019058)3.19008245
65substantia nigra development (GO:0021762)3.17633008
66intracellular protein transmembrane import (GO:0044743)3.15408558
67L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.15221829
68succinate metabolic process (GO:0006105)3.14808317
69protein maturation by protein folding (GO:0022417)3.14565711
70negative regulation of potassium ion transmembrane transport (GO:1901380)3.14366983
71regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.12769887
72establishment of protein localization to mitochondrial membrane (GO:0090151)3.12463702
73negative regulation of telomere maintenance (GO:0032205)3.12441460
74branched-chain amino acid catabolic process (GO:0009083)3.12211859
75UTP biosynthetic process (GO:0006228)3.10376662
76C4-dicarboxylate transport (GO:0015740)3.09977260
77ribonucleoside triphosphate biosynthetic process (GO:0009201)3.09975118
78protein localization to mitochondrion (GO:0070585)3.09804354
79ubiquinone metabolic process (GO:0006743)3.09446185
80myofibril assembly (GO:0030239)3.09323318
81regulation of membrane repolarization (GO:0060306)3.08319286
82proton transport (GO:0015992)3.07507674
83regulation of cell communication by electrical coupling (GO:0010649)3.06708196
84positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.06195973
85platelet dense granule organization (GO:0060155)3.04632546
86hydrogen transport (GO:0006818)3.04264204
87inner mitochondrial membrane organization (GO:0007007)3.03884159
88DNA deamination (GO:0045006)3.03698606
89synaptic vesicle exocytosis (GO:0016079)3.03681762
90guanosine-containing compound biosynthetic process (GO:1901070)3.02671415
91neuromuscular process controlling posture (GO:0050884)3.02389767
92transcription elongation from RNA polymerase III promoter (GO:0006385)3.02328248
93termination of RNA polymerase III transcription (GO:0006386)3.02328248
94negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.01298083
95translation (GO:0006412)3.00889682
96protein neddylation (GO:0045116)3.00157269
97regulation of cellular amino acid metabolic process (GO:0006521)2.98529960
98membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.97204600
99heart process (GO:0003015)2.96060329
100heart contraction (GO:0060047)2.96060329
101mitochondrial transport (GO:0006839)2.95787572
102cellular protein complex disassembly (GO:0043624)2.94795971
103regulation of relaxation of muscle (GO:1901077)2.93860054
104CTP metabolic process (GO:0046036)2.92520658
105CTP biosynthetic process (GO:0006241)2.92520658
106adult heart development (GO:0007512)2.92457749
107nucleoside diphosphate phosphorylation (GO:0006165)2.90838609
108presynaptic membrane organization (GO:0097090)2.90457309
109cerebral cortex radially oriented cell migration (GO:0021799)2.90436507
110gluconeogenesis (GO:0006094)2.89804631
111UTP metabolic process (GO:0046051)2.89777140
112pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.89591917
113DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.87441658
114cullin deneddylation (GO:0010388)2.86958989
115quinone biosynthetic process (GO:1901663)2.86100707
116aerobic respiration (GO:0009060)2.84694118
117neuron cell-cell adhesion (GO:0007158)2.82940995
118* RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.82924309
119* tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.82924309
120regulation of acyl-CoA biosynthetic process (GO:0050812)2.82059619
121negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.81707320
122regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.80425358
123neurotransmitter uptake (GO:0001504)2.80085131
124DNA damage response, detection of DNA damage (GO:0042769)2.79337226
125proteasome assembly (GO:0043248)2.77942231
126nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.77078907
127regulation of actin filament-based movement (GO:1903115)2.76828567
128cardiac muscle contraction (GO:0060048)2.76743857
129actin-mediated cell contraction (GO:0070252)2.76321957
130regulation of sarcomere organization (GO:0060297)2.75400642
131long-chain fatty acid biosynthetic process (GO:0042759)2.74973459
132dicarboxylic acid catabolic process (GO:0043649)2.73577556
133signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.72273456
134intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.72273456
135nucleoside triphosphate biosynthetic process (GO:0009142)2.72254346
136creatine metabolic process (GO:0006600)2.72241882
137negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.71772478
138detection of calcium ion (GO:0005513)2.70822532
139cerebellar granule cell differentiation (GO:0021707)2.70169920
140fatty acid elongation (GO:0030497)2.67549478
141mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.64890565
142regulation of cofactor metabolic process (GO:0051193)2.64694796
143regulation of coenzyme metabolic process (GO:0051196)2.64694796
144ventricular cardiac muscle cell action potential (GO:0086005)2.64139841
145cardiac muscle tissue morphogenesis (GO:0055008)2.63638663
146regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.63087291
147positive regulation of potassium ion transmembrane transport (GO:1901381)2.60364471
148positive regulation of action potential (GO:0045760)2.57644473
149transferrin transport (GO:0033572)2.57004651
150regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.56522199
151negative regulation of synaptic transmission, GABAergic (GO:0032229)2.55039807
152amino acid salvage (GO:0043102)2.47858712
153L-methionine salvage (GO:0071267)2.47858712
154L-methionine biosynthetic process (GO:0071265)2.47858712
155protein deneddylation (GO:0000338)2.47351409
156regulation of skeletal muscle contraction (GO:0014819)2.46569576
157generation of precursor metabolites and energy (GO:0006091)2.46199130
158ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.46000687
159positive regulation of mitochondrial fission (GO:0090141)2.45818069
160limb bud formation (GO:0060174)2.41285297
161cardiac muscle hypertrophy (GO:0003300)2.39900327
162calcium-mediated signaling using intracellular calcium source (GO:0035584)2.39728095

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.69130043
2EZH2_22144423_ChIP-Seq_EOC_Human3.92673228
3GBX2_23144817_ChIP-Seq_PC3_Human3.04128053
4ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.94526786
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.68389890
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.57913184
7MYC_18358816_ChIP-ChIP_MESCs_Mouse2.53583275
8TAF15_26573619_Chip-Seq_HEK293_Human2.53271107
9VDR_22108803_ChIP-Seq_LS180_Human2.51336741
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.43550601
11CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.38441469
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.33699317
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.31327356
14XRN2_22483619_ChIP-Seq_HELA_Human2.23271794
15* GABP_19822575_ChIP-Seq_HepG2_Human2.23241813
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.20585207
17PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.20350976
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.13250104
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.13163021
20JARID2_20075857_ChIP-Seq_MESCs_Mouse2.06409937
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06123269
22MYC_18555785_ChIP-Seq_MESCs_Mouse2.04203583
23EED_16625203_ChIP-ChIP_MESCs_Mouse2.01875442
24CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01545801
25RNF2_18974828_ChIP-Seq_MESCs_Mouse2.01144018
26EZH2_18974828_ChIP-Seq_MESCs_Mouse2.01144018
27SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.99909854
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.99876234
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.95671263
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.90141394
31REST_21632747_ChIP-Seq_MESCs_Mouse1.88693103
32VDR_23849224_ChIP-Seq_CD4+_Human1.88691155
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.88637165
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.82551873
35SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.82419866
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.80838886
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.74548656
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.74301183
39CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.74041307
40DCP1A_22483619_ChIP-Seq_HELA_Human1.73355442
41FOXP3_21729870_ChIP-Seq_TREG_Human1.73331783
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.72274537
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68093683
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62071708
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.61909181
46EZH2_27294783_Chip-Seq_ESCs_Mouse1.60837433
47BCL6_27268052_Chip-Seq_Bcells_Human1.60235407
48MYC_19030024_ChIP-ChIP_MESCs_Mouse1.59657386
49SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59232034
50TET1_21451524_ChIP-Seq_MESCs_Mouse1.59052825
51EP300_21415370_ChIP-Seq_HL-1_Mouse1.58336075
52CTCF_18555785_ChIP-Seq_MESCs_Mouse1.55850814
53FOXP1_21924763_ChIP-Seq_HESCs_Human1.55365536
54RARB_27405468_Chip-Seq_BRAIN_Mouse1.53498728
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52611643
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.52091584
57ZNF274_21170338_ChIP-Seq_K562_Hela1.51164580
58P300_19829295_ChIP-Seq_ESCs_Human1.50956231
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.50319849
60SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.49855784
61PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.49784768
62CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.49573248
63SRY_22984422_ChIP-ChIP_TESTIS_Rat1.49389410
64RNF2_27304074_Chip-Seq_ESCs_Mouse1.48575305
65ELF1_20517297_ChIP-Seq_JURKAT_Human1.47074064
66NR3C1_23031785_ChIP-Seq_PC12_Mouse1.46724439
67TTF2_22483619_ChIP-Seq_HELA_Human1.45900348
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44721394
69PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.42333964
70P68_20966046_ChIP-Seq_HELA_Human1.41988579
71JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.41628254
72SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.40759101
73YY1_22570637_ChIP-Seq_MALME-3M_Human1.38669018
74HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.36832076
75CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.36611402
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.36443166
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.36058442
78CTCF_26484167_Chip-Seq_Bcells_Mouse1.35357334
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33321005
80OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32711331
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.31779837
82BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31758167
83CBX2_27304074_Chip-Seq_ESCs_Mouse1.30696528
84EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.30489709
85GABP_17652178_ChIP-ChIP_JURKAT_Human1.29490022
86ERG_21242973_ChIP-ChIP_JURKAT_Human1.28393668
87HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.28190962
88BCAT_22108803_ChIP-Seq_LS180_Human1.25700210
89CIITA_25753668_ChIP-Seq_RAJI_Human1.25516411
90SMAD3_21741376_ChIP-Seq_EPCs_Human1.25335873
91CREB1_15753290_ChIP-ChIP_HEK293T_Human1.23892840
92ER_23166858_ChIP-Seq_MCF-7_Human1.23123605
93THAP11_20581084_ChIP-Seq_MESCs_Mouse1.22972998
94DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22955697
95E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.22949901
96BCOR_27268052_Chip-Seq_Bcells_Human1.22679419
97POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22661178
98* LXR_22292898_ChIP-Seq_THP-1_Human1.22384179
99SRF_21415370_ChIP-Seq_HL-1_Mouse1.22344207
100RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.21663774
101E2F1_20622854_ChIP-Seq_HELA_Human1.21427272
102CDX2_19796622_ChIP-Seq_MESCs_Mouse1.20439350
103MYC_19079543_ChIP-ChIP_MESCs_Mouse1.20371181
104SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.20176641
105ZNF263_19887448_ChIP-Seq_K562_Human1.19772082
106AR_21572438_ChIP-Seq_LNCaP_Human1.19295149
107TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19152878
108NELFA_20434984_ChIP-Seq_ESCs_Mouse1.18999382
109PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18965631
110FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18830851
111SMAD4_21799915_ChIP-Seq_A2780_Human1.18649263
112TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17917821
113KDM5A_27292631_Chip-Seq_BREAST_Human1.17837190
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17231286
115PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14024494
116CTCF_20526341_ChIP-Seq_ESCs_Human1.13799204
117SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.12979174
118PHF8_20622854_ChIP-Seq_HELA_Human1.12836508
119* SA1_27219007_Chip-Seq_Bcells_Human1.12732026
120FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12152146
121FUS_26573619_Chip-Seq_HEK293_Human1.10951434
122NANOG_18555785_ChIP-Seq_MESCs_Mouse1.10921226
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10802701
124SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.10623999
125RARB_24833708_ChIP-Seq_LIVER_Mouse1.10178484
126HOXB4_20404135_ChIP-ChIP_EML_Mouse1.10018606
127DROSHA_22980978_ChIP-Seq_HELA_Human1.06773973
128TBX5_21415370_ChIP-Seq_HL-1_Mouse1.06527953
129EST1_17652178_ChIP-ChIP_JURKAT_Human1.06448823
130* CTCF_27219007_Chip-Seq_Bcells_Human1.05938776
131CTCF_21964334_Chip-Seq_Bcells_Human1.05043022
132HTT_18923047_ChIP-ChIP_STHdh_Human1.03418641
133SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03281241
134ETS1_20019798_ChIP-Seq_JURKAT_Human1.02693068
135* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02316067
136MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.00899133
137NANOG_20526341_ChIP-Seq_ESCs_Human1.00529323
138ELK1_19687146_ChIP-ChIP_HELA_Human0.99166147
139PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98827117
140THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98673737
141* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98043765
142SA1_27219007_Chip-Seq_ERYTHROID_Human0.97911405
143RARA_24833708_ChIP-Seq_LIVER_Mouse0.97890954
144EOMES_21245162_ChIP-Seq_HESCs_Human0.97190877
145MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96645139
146* ERA_21632823_ChIP-Seq_H3396_Human0.96148747
147AR_25329375_ChIP-Seq_VCAP_Human0.95562650
148POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95348929
149SOX2_21211035_ChIP-Seq_LN229_Gbm0.94168856
150P300_27268052_Chip-Seq_Bcells_Human0.94069700
151RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93828571
152SPI1_20517297_ChIP-Seq_HL60_Human0.93821401
153SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93493187
154BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93120999
155PRDM14_20953172_ChIP-Seq_ESCs_Human0.92657960
156POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.92597573
157PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.92423703
158CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90168970
159MYC_18940864_ChIP-ChIP_HL60_Human0.89126622
160ELK1_22589737_ChIP-Seq_MCF10A_Human0.88548831
161ZFX_18555785_ChIP-Seq_MESCs_Mouse0.88129193
162WT1_19549856_ChIP-ChIP_CCG9911_Human0.87926871
163* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.87906032
164KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87658487
165CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.87444939
166HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.86645024
167RNF2_27304074_Chip-Seq_NSC_Mouse0.86123721
168IRF1_19129219_ChIP-ChIP_H3396_Human0.84469436
169SOX9_26525672_Chip-Seq_HEART_Mouse0.84416125
170NANOG_19829295_ChIP-Seq_ESCs_Human0.83148288
171SOX2_19829295_ChIP-Seq_ESCs_Human0.83148288
172YY1_21170310_ChIP-Seq_MESCs_Mouse0.83074886
173NCOR_22424771_ChIP-Seq_293T_Human0.82863860
174IKZF1_21737484_ChIP-ChIP_HCT116_Human0.82273086
175TRIM28_21343339_ChIP-Seq_HEK293_Human0.81909792
176REST_19997604_ChIP-ChIP_NEURONS_Mouse0.80745494
177TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.80360602
178MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.80039934
179ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.79117788

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis4.99535495
2MP0002653_abnormal_ependyma_morphology3.04590376
3MP0003880_abnormal_central_pattern2.94266608
4MP0000751_myopathy2.94116740
5MP0004036_abnormal_muscle_relaxation2.83712653
6MP0008789_abnormal_olfactory_epithelium2.69685457
7MP0010030_abnormal_orbit_morphology2.63291747
8MP0003646_muscle_fatigue2.58255063
9MP0004215_abnormal_myocardial_fiber2.57477247
10MP0004145_abnormal_muscle_electrophysio2.54496699
11MP0002638_abnormal_pupillary_reflex2.43540977
12MP0004084_abnormal_cardiac_muscle2.40145964
13MP0000749_muscle_degeneration2.37676879
14MP0002163_abnormal_gland_morphology2.32378708
15MP0001529_abnormal_vocalization2.25809480
16MP0005499_abnormal_olfactory_system2.19449462
17MP0005394_taste/olfaction_phenotype2.19449462
18MP0004859_abnormal_synaptic_plasticity2.15750012
19MP0000372_irregular_coat_pigmentation2.13698470
20MP0003329_amyloid_beta_deposits2.13373570
21MP0003635_abnormal_synaptic_transmissio2.10128602
22MP0002064_seizures2.09833734
23MP0003186_abnormal_redox_activity2.06132823
24MP0004270_analgesia2.01950969
25MP0009046_muscle_twitch1.97959908
26MP0001440_abnormal_grooming_behavior1.94533734
27MP0006276_abnormal_autonomic_nervous1.93791428
28MP0001905_abnormal_dopamine_level1.83936443
29MP0002272_abnormal_nervous_system1.83748784
30MP0003137_abnormal_impulse_conducting1.83449117
31MP0009745_abnormal_behavioral_response1.82186986
32MP0003011_delayed_dark_adaptation1.81461503
33MP0002972_abnormal_cardiac_muscle1.80354848
34MP0009379_abnormal_foot_pigmentation1.75792775
35MP0002736_abnormal_nociception_after1.74727601
36MP0005620_abnormal_muscle_contractility1.65690483
37MP0001968_abnormal_touch/_nociception1.64095493
38MP0006036_abnormal_mitochondrial_physio1.63656851
39MP0004133_heterotaxia1.59813750
40MP0000566_synostosis1.58864526
41MP0002572_abnormal_emotion/affect_behav1.58184497
42MP0005330_cardiomyopathy1.57578959
43MP0003950_abnormal_plasma_membrane1.55455689
44MP0004484_altered_response_of1.55332624
45MP0006035_abnormal_mitochondrial_morpho1.54766262
46MP0002822_catalepsy1.53209673
47MP0002734_abnormal_mechanical_nocicepti1.52944549
48MP0002063_abnormal_learning/memory/cond1.51108041
49MP0003122_maternal_imprinting1.50335662
50MP0001486_abnormal_startle_reflex1.48176444
51MP0004142_abnormal_muscle_tone1.48154333
52MP0005075_abnormal_melanosome_morpholog1.48087280
53MP0001764_abnormal_homeostasis1.47580887
54MP0003787_abnormal_imprinting1.47550990
55MP0000747_muscle_weakness1.46410144
56MP0009780_abnormal_chondrocyte_physiolo1.45647247
57MP0002102_abnormal_ear_morphology1.43445843
58MP0002106_abnormal_muscle_physiology1.41946268
59MP0004085_abnormal_heartbeat1.40613970
60MP0004087_abnormal_muscle_fiber1.38547927
61MP0000049_abnormal_middle_ear1.37950948
62MP0004924_abnormal_behavior1.37782672
63MP0005386_behavior/neurological_phenoty1.37782672
64MP0001502_abnormal_circadian_rhythm1.34539428
65MP0000750_abnormal_muscle_regeneration1.33276095
66MP0005645_abnormal_hypothalamus_physiol1.32336044
67MP0006292_abnormal_olfactory_placode1.30192843
68MP0008569_lethality_at_weaning1.25788507
69MP0005369_muscle_phenotype1.25400510
70MP0002067_abnormal_sensory_capabilities1.25067608
71MP0006138_congestive_heart_failure1.24323164
72MP0002127_abnormal_cardiovascular_syste1.24204740
73MP0002332_abnormal_exercise_endurance1.22966386
74MP0003786_premature_aging1.22420903
75MP0005670_abnormal_white_adipose1.22066021
76MP0001485_abnormal_pinna_reflex1.21179764
77MP0001984_abnormal_olfaction1.19209257
78MP0005451_abnormal_body_composition1.19050081
79MP0000778_abnormal_nervous_system1.17088009
80MP0005423_abnormal_somatic_nervous1.16395382
81MP0005385_cardiovascular_system_phenoty1.12695640
82MP0001544_abnormal_cardiovascular_syste1.12695640
83MP0000026_abnormal_inner_ear1.12299028
84MP0005646_abnormal_pituitary_gland1.10508219
85MP0002938_white_spotting1.10352987
86MP0002249_abnormal_larynx_morphology1.10285521
87MP0000013_abnormal_adipose_tissue1.09286166
88MP0002269_muscular_atrophy1.08453757
89MP0006072_abnormal_retinal_apoptosis1.08154093
90MP0000920_abnormal_myelination1.07310040
91MP0001970_abnormal_pain_threshold1.07184174
92MP0000759_abnormal_skeletal_muscle1.06351796
93MP0002733_abnormal_thermal_nociception1.04496515
94MP0004130_abnormal_muscle_cell1.03312733
95MP0003123_paternal_imprinting1.03256979
96MP0002184_abnormal_innervation1.03244264
97MP0002234_abnormal_pharynx_morphology1.02860606
98MP0008995_early_reproductive_senescence1.02751421
99MP0008058_abnormal_DNA_repair1.02068064
100MP0002066_abnormal_motor_capabilities/c1.00884805
101MP0005083_abnormal_biliary_tract1.00545836
102MP0009697_abnormal_copulation1.00312764
103MP0008875_abnormal_xenobiotic_pharmacok1.00134632
104MP0005551_abnormal_eye_electrophysiolog0.98813991
105MP0002735_abnormal_chemical_nociception0.97840042
106MP0005408_hypopigmentation0.97212828
107MP0004043_abnormal_pH_regulation0.96510915
108MP0005377_hearing/vestibular/ear_phenot0.93788393
109MP0003878_abnormal_ear_physiology0.93788393
110MP0008775_abnormal_heart_ventricle0.91735170
111MP0002095_abnormal_skin_pigmentation0.90998727
112MP0004233_abnormal_muscle_weight0.90439358
113MP0003634_abnormal_glial_cell0.89854797
114MP0005584_abnormal_enzyme/coenzyme_acti0.89505346
115MP0008872_abnormal_physiological_respon0.88106455
116MP0002229_neurodegeneration0.88076442
117MP0005171_absent_coat_pigmentation0.87537888
118MP0002132_abnormal_respiratory_system0.86371074
119MP0003172_abnormal_lysosome_physiology0.85814693
120MP0001501_abnormal_sleep_pattern0.84791339
121MP0010386_abnormal_urinary_bladder0.83524102
122MP0000230_abnormal_systemic_arterial0.80837802
123MP0002882_abnormal_neuron_morphology0.80768698
124MP0005253_abnormal_eye_physiology0.80471002
125MP0000604_amyloidosis0.80343471
126MP0004885_abnormal_endolymph0.80055368
127MP0003938_abnormal_ear_development0.79707089
128MP0002557_abnormal_social/conspecific_i0.79276071
129MP0005332_abnormal_amino_acid0.79107041
130MP0001293_anophthalmia0.78716040
131MP0003136_yellow_coat_color0.77999957
132MP0000678_abnormal_parathyroid_gland0.77640570
133MP0003690_abnormal_glial_cell0.76138057
134MP0005535_abnormal_body_temperature0.74208876
135MP0002909_abnormal_adrenal_gland0.73514139
136MP0004147_increased_porphyrin_level0.73240350
137MP0000955_abnormal_spinal_cord0.72226031
138MP0003806_abnormal_nucleotide_metabolis0.71694585
139MP0009384_cardiac_valve_regurgitation0.71550180
140MP0002277_abnormal_respiratory_mucosa0.71298353
141MP0005379_endocrine/exocrine_gland_phen0.70681214
142MP0005058_abnormal_lysosome_morphology0.70451859
143MP0000733_abnormal_muscle_development0.68907601
144MP0002177_abnormal_outer_ear0.68455933
145MP0001963_abnormal_hearing_physiology0.67955132
146MP0008932_abnormal_embryonic_tissue0.66113979
147MP0002752_abnormal_somatic_nervous0.65890781
148MP0002282_abnormal_trachea_morphology0.65283914
149MP0000358_abnormal_cell_content/0.63471696
150MP0000343_altered_response_to0.63106936
151MP0003879_abnormal_hair_cell0.61612093
152MP0005084_abnormal_gallbladder_morpholo0.61135905
153MP0003121_genomic_imprinting0.61101835

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.95820056
2Abnormal mitochondria in muscle tissue (HP:0008316)5.60799038
3Progressive macrocephaly (HP:0004481)5.20220873
4Acute encephalopathy (HP:0006846)5.03591236
5Mitochondrial inheritance (HP:0001427)4.80908378
6Focal motor seizures (HP:0011153)4.33645582
7Calf muscle hypertrophy (HP:0008981)4.24792498
8Muscle hypertrophy of the lower extremities (HP:0008968)4.23851324
9Increased CSF lactate (HP:0002490)4.04420742
10Atonic seizures (HP:0010819)3.96201541
11Exercise-induced myalgia (HP:0003738)3.92104150
12Hepatocellular necrosis (HP:0001404)3.80328396
13Cerebral edema (HP:0002181)3.62442135
14Sudden death (HP:0001699)3.51325609
15Hepatic necrosis (HP:0002605)3.50470472
16Neuroendocrine neoplasm (HP:0100634)3.48312195
17Pheochromocytoma (HP:0002666)3.43959511
18Exercise-induced muscle cramps (HP:0003710)3.42250652
19Increased intramyocellular lipid droplets (HP:0012240)3.36135445
20Optic disc pallor (HP:0000543)3.23088166
21Exercise intolerance (HP:0003546)3.23002875
22Increased serum pyruvate (HP:0003542)3.12722486
23Abnormality of glycolysis (HP:0004366)3.12722486
24Abnormality of the calf musculature (HP:0001430)3.08208242
25Increased hepatocellular lipid droplets (HP:0006565)3.06737834
26Respiratory failure (HP:0002878)3.05806196
27Increased muscle lipid content (HP:0009058)3.02992308
28Myopathic facies (HP:0002058)3.01331702
29Leukodystrophy (HP:0002415)2.93664103
30Epileptic encephalopathy (HP:0200134)2.92323822
31Lactic acidosis (HP:0003128)2.87972958
32Lipid accumulation in hepatocytes (HP:0006561)2.86888541
33Myoglobinuria (HP:0002913)2.84300767
34Renal Fanconi syndrome (HP:0001994)2.82530410
35Decreased activity of mitochondrial respiratory chain (HP:0008972)2.73450528
36Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.73450528
37Sensory axonal neuropathy (HP:0003390)2.69990973
38Myokymia (HP:0002411)2.67679666
39Absence seizures (HP:0002121)2.65910077
40Muscle fiber splitting (HP:0003555)2.63471962
41Ketoacidosis (HP:0001993)2.62365125
423-Methylglutaconic aciduria (HP:0003535)2.59230486
43Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.59131066
44Cerebral palsy (HP:0100021)2.54146299
45Type 2 muscle fiber atrophy (HP:0003554)2.53961831
46Prolonged QT interval (HP:0001657)2.53122457
47Hypoplastic left heart (HP:0004383)2.53098085
48Exertional dyspnea (HP:0002875)2.52962004
49Muscle fiber atrophy (HP:0100295)2.50089225
50Dialeptic seizures (HP:0011146)2.49496135
51Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.48582493
52Palpitations (HP:0001962)2.45779574
53Reticulocytopenia (HP:0001896)2.44704894
54Methylmalonic aciduria (HP:0012120)2.44144383
55EMG: myopathic abnormalities (HP:0003458)2.41753520
56Medial flaring of the eyebrow (HP:0010747)2.37758947
57Focal seizures (HP:0007359)2.36106054
58Syncope (HP:0001279)2.35901497
59Nephronophthisis (HP:0000090)2.32677782
60Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.32160316
61Molar tooth sign on MRI (HP:0002419)2.32011216
62Abnormality of midbrain morphology (HP:0002418)2.32011216
63Agammaglobulinemia (HP:0004432)2.31999948
64Myotonia (HP:0002486)2.31764483
65Type 1 muscle fiber predominance (HP:0003803)2.31042410
66Respiratory difficulties (HP:0002880)2.29998322
67Generalized aminoaciduria (HP:0002909)2.29927134
68Generalized tonic-clonic seizures (HP:0002069)2.25292084
69Distal arthrogryposis (HP:0005684)2.25170500
70Hyperventilation (HP:0002883)2.22796273
71Hyporeflexia of lower limbs (HP:0002600)2.22511556
72Parakeratosis (HP:0001036)2.22395374
73Ventricular tachycardia (HP:0004756)2.21159587
74Increased serum lactate (HP:0002151)2.19679581
75Sclerocornea (HP:0000647)2.18241284
76Ulnar deviation of the wrist (HP:0003049)2.17913657
77X-linked dominant inheritance (HP:0001423)2.17745111
78CNS demyelination (HP:0007305)2.16870556
79Neurofibrillary tangles (HP:0002185)2.16698540
80Unsteady gait (HP:0002317)2.14272204
81Glycosuria (HP:0003076)2.05888609
82Abnormality of urine glucose concentration (HP:0011016)2.05888609
83Lethargy (HP:0001254)2.04770292
84Testicular atrophy (HP:0000029)2.04280173
85Atrial fibrillation (HP:0005110)2.03784419
86Retinal dysplasia (HP:0007973)2.00267705
87Abnormality of cells of the erythroid lineage (HP:0012130)2.00224380
88Lipoatrophy (HP:0100578)2.00137714
89Visual hallucinations (HP:0002367)1.99276566
90Emotional lability (HP:0000712)1.99122374
91Methylmalonic acidemia (HP:0002912)1.98992568
92Primary atrial arrhythmia (HP:0001692)1.98660731
93Congenital malformation of the right heart (HP:0011723)1.98528623
94Double outlet right ventricle (HP:0001719)1.98528623
95Conjunctival hamartoma (HP:0100780)1.97984727
96Cholecystitis (HP:0001082)1.97961206
97Abnormal gallbladder physiology (HP:0012438)1.97961206
98Hypoplastic heart (HP:0001961)1.97523445
99Left ventricular hypertrophy (HP:0001712)1.96942879
100Abnormal number of erythroid precursors (HP:0012131)1.96744977
101Round ear (HP:0100830)1.96712347
102Muscle stiffness (HP:0003552)1.95902592
103Supraventricular tachycardia (HP:0004755)1.95599210
104Type I transferrin isoform profile (HP:0003642)1.95508217
105Abnormal respiratory epithelium morphology (HP:0012253)1.94958141
106Abnormal respiratory motile cilium morphology (HP:0005938)1.94958141
107Athetosis (HP:0002305)1.93854157
108Dicarboxylic aciduria (HP:0003215)1.92323204
109Abnormality of dicarboxylic acid metabolism (HP:0010995)1.92323204
110Delayed CNS myelination (HP:0002188)1.90966749
111J-shaped sella turcica (HP:0002680)1.90220892
112Abnormality of renal resorption (HP:0011038)1.90005862
113Ragged-red muscle fibers (HP:0003200)1.89480136
114Abnormality of fatty-acid metabolism (HP:0004359)1.89112290
115Delayed gross motor development (HP:0002194)1.88681009
116Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.88598681
117Aplasia/Hypoplasia of the sacrum (HP:0008517)1.88537724
118Muscle fiber inclusion bodies (HP:0100299)1.88332739
119True hermaphroditism (HP:0010459)1.87395795
120Cerebral hypomyelination (HP:0006808)1.87357389
121Pancreatic fibrosis (HP:0100732)1.87029128
122Severe visual impairment (HP:0001141)1.86785875
123Supraventricular arrhythmia (HP:0005115)1.86337316
124Difficulty running (HP:0009046)1.84408710
125Nemaline bodies (HP:0003798)1.83972415
126Congenital primary aphakia (HP:0007707)1.83459555
127Rhabdomyolysis (HP:0003201)1.82226053
128Abnormality of the labia minora (HP:0012880)1.80310194
129Progressive microcephaly (HP:0000253)1.78354976
130Ventricular arrhythmia (HP:0004308)1.78042536
131Gait imbalance (HP:0002141)1.77876237
132Delusions (HP:0000746)1.77203700
133Microglossia (HP:0000171)1.76755402
134Pancreatic cysts (HP:0001737)1.76585920
135Dilated cardiomyopathy (HP:0001644)1.76418259
136Severe muscular hypotonia (HP:0006829)1.75874799
137Hyperglycinemia (HP:0002154)1.75793623
138Neck muscle weakness (HP:0000467)1.75244348
139Rimmed vacuoles (HP:0003805)1.74451861
140Cerebral inclusion bodies (HP:0100314)1.74298896
141Renal cortical cysts (HP:0000803)1.74010485
142Nephrogenic diabetes insipidus (HP:0009806)1.73042991
143Abnormal protein N-linked glycosylation (HP:0012347)1.72660068
144Abnormal protein glycosylation (HP:0012346)1.72660068
145Abnormal glycosylation (HP:0012345)1.72660068
146Hyperphosphaturia (HP:0003109)1.71703428
147Abnormal EKG (HP:0003115)1.70982061
148Facial hemangioma (HP:0000329)1.69841925

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.03576334
2ARAF3.61348022
3OBSCN3.04426665
4PNCK2.78112913
5CCNB12.72812264
6MAP4K22.56770305
7PHKG12.54348073
8PHKG22.54348073
9TRIM282.52063880
10NME12.44941875
11FGFR22.31061932
12STK162.29829470
13MYLK2.27153350
14LIMK12.23459411
15TESK12.23205338
16BCKDK2.19040467
17MST42.00789171
18EPHA41.98715857
19STK391.97294728
20NME21.95181748
21TLK11.93107688
22NTRK31.80519525
23PDK31.78279834
24PDK41.78279834
25MUSK1.77446639
26CASK1.76583420
27OXSR11.70244845
28MAP3K41.63736657
29NTRK21.61978791
30GRK71.58852657
31PLK21.53338451
32WNK41.52384585
33TESK21.51889366
34MARK11.51694414
35MAP2K71.48947154
36NEK11.43263866
37PDK21.41200875
38MAPKAPK31.39983690
39CDK191.38472109
40UHMK11.37766645
41BRAF1.35862971
42TSSK61.27840672
43CAMK2D1.22114728
44SIK31.19794318
45DAPK11.18618695
46CAMK2A1.18290261
47PAK31.15197764
48MINK11.14896927
49TAOK21.14777672
50SRPK11.13168787
51BUB11.11339355
52EPHA21.11295832
53STK241.11100172
54CSNK1G11.10391971
55CAMK2B1.10341190
56BCR1.09884501
57MAPK131.08998592
58FRK1.07844897
59MAP2K61.06986753
60CAMK2G1.05697515
61CSNK1A1L1.05215942
62GRK51.05128338
63TAF11.04624802
64PRKD31.04262384
65DAPK21.03924168
66MAPK121.03800102
67CSNK1G21.02355623
68KDR1.01415194
69PKN11.01184168
70DYRK1B1.00701024
71LMTK21.00140426
72MAP3K120.99454074
73TTN0.97981580
74ROCK20.97921818
75MAP3K90.97807043
76ZAK0.94898476
77GRK10.93201909
78INSRR0.91524115
79LRRK20.90431891
80MAP3K110.87681660
81RAF10.84409424
82TNK20.82946356
83NTRK10.82522490
84PRKCE0.81904713
85WNK30.81602252
86PRKCG0.80557470
87FGR0.80207191
88STK38L0.79863519
89MAPKAPK50.77410380
90ABL20.77099315
91PINK10.76280485
92BMPR1B0.76027576
93BRSK10.74729452
94SGK2230.73787730
95SGK4940.73787730
96PIK3CA0.73032655
97PRKD20.72734150
98CDK50.71740642
99MAPK150.71157107
100ILK0.71116629
101AURKA0.71046744
102IKBKB0.70716707
103EPHB20.70114192
104KSR20.69752685
105CAMKK20.69624823
106DYRK30.69600814
107AKT30.68702978
108MAP2K40.67993676
109FER0.63604256
110CDK140.63529474
111PRKACA0.63315650
112ROCK10.62742485
113NUAK10.62330834
114DYRK20.62280991
115TAOK10.60960855
116CDC42BPA0.58455166
117DYRK1A0.58082874
118PTK2B0.57434492
119SIK10.57358053
120CDK80.56995282
121PAK10.56666121
122PRKD10.55505794
123GRK60.55290004
124CDK180.54269549
125PIM20.52863731
126CDK150.51944336
127MAP3K50.51900338
128DAPK30.51006356
129IRAK40.50354627
130MARK20.47793933
131TBK10.47648107
132CSNK1G30.46737879
133CDK11A0.46306638
134CAMK10.45598588
135ERN10.45251192
136ERBB40.45144678
137VRK10.44417951
138PRKCI0.44386034
139PLK30.44337989
140STK110.44157990
141RPS6KA50.44156637
142PRKCH0.43856676
143KSR10.42567871
144ADRBK10.42438316
145CSNK2A20.41227324
146TIE10.39879189
147PRKCQ0.38517216
148CSNK2A10.38359613
149BMPR20.38265736
150MAPK110.36626439
151AURKB0.34257610
152CSNK1A10.33810043
153IRAK20.32572086
154SMG10.31676059
155PBK0.30897034
156MAP3K70.29635932
157DMPK0.29566190

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.37448442
2Parkinsons disease_Homo sapiens_hsa050124.59536373
3Alzheimers disease_Homo sapiens_hsa050103.54781089
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.41251216
5Cardiac muscle contraction_Homo sapiens_hsa042603.30830001
6Huntingtons disease_Homo sapiens_hsa050163.05548359
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.62667609
8Collecting duct acid secretion_Homo sapiens_hsa049662.32369494
9Sulfur relay system_Homo sapiens_hsa041222.26058157
10Protein export_Homo sapiens_hsa030602.16046042
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.98885094
12Fatty acid elongation_Homo sapiens_hsa000621.98463951
13Propanoate metabolism_Homo sapiens_hsa006401.95030424
14Base excision repair_Homo sapiens_hsa034101.87574465
15Nicotine addiction_Homo sapiens_hsa050331.87433371
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.87379106
17Homologous recombination_Homo sapiens_hsa034401.83107943
18Synaptic vesicle cycle_Homo sapiens_hsa047211.76011486
19GABAergic synapse_Homo sapiens_hsa047271.65314595
20Vibrio cholerae infection_Homo sapiens_hsa051101.62010451
21Proteasome_Homo sapiens_hsa030501.60714201
22Mismatch repair_Homo sapiens_hsa034301.55105490
23Pyruvate metabolism_Homo sapiens_hsa006201.54407610
24Pyrimidine metabolism_Homo sapiens_hsa002401.52624485
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.50143414
26Butanoate metabolism_Homo sapiens_hsa006501.49258737
27Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.46929468
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34328632
29Carbon metabolism_Homo sapiens_hsa012001.32738382
30Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.27357778
31Glutathione metabolism_Homo sapiens_hsa004801.26814961
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26418335
33Vitamin B6 metabolism_Homo sapiens_hsa007501.19150454
34Dilated cardiomyopathy_Homo sapiens_hsa054141.17205264
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15842064
36Circadian entrainment_Homo sapiens_hsa047131.10666112
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.08904214
38DNA replication_Homo sapiens_hsa030301.08439205
39Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.07453084
40Insulin secretion_Homo sapiens_hsa049111.05373493
41Serotonergic synapse_Homo sapiens_hsa047261.04843998
42Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.04086451
43Glutamatergic synapse_Homo sapiens_hsa047241.03966587
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.03434599
45Cyanoamino acid metabolism_Homo sapiens_hsa004601.03049001
46Amphetamine addiction_Homo sapiens_hsa050311.01767076
47Morphine addiction_Homo sapiens_hsa050321.00017229
48Long-term potentiation_Homo sapiens_hsa047200.99562387
49Galactose metabolism_Homo sapiens_hsa000520.99353173
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99348349
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.98733060
52Primary immunodeficiency_Homo sapiens_hsa053400.97756336
53Nucleotide excision repair_Homo sapiens_hsa034200.97566950
54Fanconi anemia pathway_Homo sapiens_hsa034600.94846357
55Taste transduction_Homo sapiens_hsa047420.93306050
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89095638
57Cocaine addiction_Homo sapiens_hsa050300.87675579
58Dopaminergic synapse_Homo sapiens_hsa047280.87618767
59Pancreatic secretion_Homo sapiens_hsa049720.86203339
60Pentose phosphate pathway_Homo sapiens_hsa000300.85632062
61Fatty acid metabolism_Homo sapiens_hsa012120.84631290
62Sulfur metabolism_Homo sapiens_hsa009200.82980907
63Long-term depression_Homo sapiens_hsa047300.82123039
64Calcium signaling pathway_Homo sapiens_hsa040200.81646858
65RNA polymerase_Homo sapiens_hsa030200.80170545
66Folate biosynthesis_Homo sapiens_hsa007900.80084455
67Arginine and proline metabolism_Homo sapiens_hsa003300.79257780
68Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.78506986
69Biosynthesis of amino acids_Homo sapiens_hsa012300.78381184
70Ether lipid metabolism_Homo sapiens_hsa005650.76831311
71Steroid biosynthesis_Homo sapiens_hsa001000.76612186
72Basal transcription factors_Homo sapiens_hsa030220.75403595
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74550005
74Renin secretion_Homo sapiens_hsa049240.74454684
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.73673224
76Salivary secretion_Homo sapiens_hsa049700.72979987
77Regulation of autophagy_Homo sapiens_hsa041400.71053323
78Metabolic pathways_Homo sapiens_hsa011000.69245051
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69169685
80Non-homologous end-joining_Homo sapiens_hsa034500.68824250
81Gastric acid secretion_Homo sapiens_hsa049710.67161141
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66379298
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.64274962
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62380987
85RNA degradation_Homo sapiens_hsa030180.62252527
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62093023
87Olfactory transduction_Homo sapiens_hsa047400.61420208
88Fatty acid degradation_Homo sapiens_hsa000710.60698785
89Oxytocin signaling pathway_Homo sapiens_hsa049210.60527905
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.59320548
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58419574
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.57310422
93Cholinergic synapse_Homo sapiens_hsa047250.57156456
94Spliceosome_Homo sapiens_hsa030400.54093552
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53557828
96cGMP-PKG signaling pathway_Homo sapiens_hsa040220.52397085
97Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.52357450
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51716391
99Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50606430
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48818886
101Melanogenesis_Homo sapiens_hsa049160.47775413
102Glucagon signaling pathway_Homo sapiens_hsa049220.47187181
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46895865
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.46673523
105Chemical carcinogenesis_Homo sapiens_hsa052040.43543422
106Arachidonic acid metabolism_Homo sapiens_hsa005900.43451534
107Axon guidance_Homo sapiens_hsa043600.42773905
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.42665890
109Asthma_Homo sapiens_hsa053100.41624870
110Aldosterone synthesis and secretion_Homo sapiens_hsa049250.41141574
111Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41133221
112Linoleic acid metabolism_Homo sapiens_hsa005910.40244867
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40194395
114Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39983736
115Gap junction_Homo sapiens_hsa045400.38932272
116Peroxisome_Homo sapiens_hsa041460.38314947
117SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38020071
118Cysteine and methionine metabolism_Homo sapiens_hsa002700.37677240
119Starch and sucrose metabolism_Homo sapiens_hsa005000.37609711
120Phototransduction_Homo sapiens_hsa047440.37601063
121PPAR signaling pathway_Homo sapiens_hsa033200.36759071
122GnRH signaling pathway_Homo sapiens_hsa049120.36463099
123Rheumatoid arthritis_Homo sapiens_hsa053230.36087912
124Circadian rhythm_Homo sapiens_hsa047100.35556250
125Tyrosine metabolism_Homo sapiens_hsa003500.35291085
126cAMP signaling pathway_Homo sapiens_hsa040240.34879673
127Fat digestion and absorption_Homo sapiens_hsa049750.34771238
128Tryptophan metabolism_Homo sapiens_hsa003800.32819908
129Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31327407
130Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31257199
131Primary bile acid biosynthesis_Homo sapiens_hsa001200.30427716
132Glycerophospholipid metabolism_Homo sapiens_hsa005640.29716006
133Autoimmune thyroid disease_Homo sapiens_hsa053200.29573458
134Purine metabolism_Homo sapiens_hsa002300.28431795
135Arginine biosynthesis_Homo sapiens_hsa002200.27316406
136Hedgehog signaling pathway_Homo sapiens_hsa043400.27094448
137Fructose and mannose metabolism_Homo sapiens_hsa000510.26897660
138Ribosome_Homo sapiens_hsa030100.26092182
139beta-Alanine metabolism_Homo sapiens_hsa004100.25939098
140alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24712254
141Phenylalanine metabolism_Homo sapiens_hsa003600.24085712
142Viral myocarditis_Homo sapiens_hsa054160.23750883
143Allograft rejection_Homo sapiens_hsa053300.22356582
144Epstein-Barr virus infection_Homo sapiens_hsa051690.21752999
145Mineral absorption_Homo sapiens_hsa049780.21465646
146p53 signaling pathway_Homo sapiens_hsa041150.19878395
147N-Glycan biosynthesis_Homo sapiens_hsa005100.18462626
148One carbon pool by folate_Homo sapiens_hsa006700.17082417
149RNA transport_Homo sapiens_hsa030130.16761617

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