TRMT112

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.44113433
2viral transcription (GO:0019083)7.07857239
3translational termination (GO:0006415)6.79096337
4ribosomal small subunit biogenesis (GO:0042274)6.69445137
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.15379251
6cotranslational protein targeting to membrane (GO:0006613)6.11011332
7protein targeting to ER (GO:0045047)6.03286072
8DNA deamination (GO:0045006)5.84198065
9translational elongation (GO:0006414)5.81867933
10establishment of protein localization to endoplasmic reticulum (GO:0072599)5.74199986
11protein localization to endoplasmic reticulum (GO:0070972)5.73170848
12maturation of SSU-rRNA (GO:0030490)5.65032632
13viral life cycle (GO:0019058)5.32176532
14cellular protein complex disassembly (GO:0043624)5.29285112
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.18436061
16translational initiation (GO:0006413)5.05932881
17ribosomal large subunit biogenesis (GO:0042273)4.72338762
18proteasome assembly (GO:0043248)4.66645662
19protein complex disassembly (GO:0043241)4.56045193
20translation (GO:0006412)4.40170991
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.37640887
22macromolecular complex disassembly (GO:0032984)4.30807860
23ATP synthesis coupled proton transport (GO:0015986)4.21716693
24energy coupled proton transport, down electrochemical gradient (GO:0015985)4.21716693
25rRNA modification (GO:0000154)4.13164940
26nuclear-transcribed mRNA catabolic process (GO:0000956)4.03448740
27ribonucleoprotein complex biogenesis (GO:0022613)3.99553752
28transcription elongation from RNA polymerase III promoter (GO:0006385)3.97619864
29termination of RNA polymerase III transcription (GO:0006386)3.97619864
30protein targeting to membrane (GO:0006612)3.90616987
31telomere maintenance via semi-conservative replication (GO:0032201)3.89913319
32mRNA catabolic process (GO:0006402)3.84417746
33deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.81561687
34protein localization to mitochondrion (GO:0070585)3.76548468
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.74433210
36nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.73666964
37mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.71303319
38mitochondrial respiratory chain complex I assembly (GO:0032981)3.71303319
39NADH dehydrogenase complex assembly (GO:0010257)3.71303319
40inner mitochondrial membrane organization (GO:0007007)3.70455283
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.66874844
42negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.66628835
43protein complex biogenesis (GO:0070271)3.61549380
44cellular component biogenesis (GO:0044085)3.60241711
45rRNA processing (GO:0006364)3.59587125
46ATP biosynthetic process (GO:0006754)3.59008123
47chaperone-mediated protein transport (GO:0072321)3.58876779
48positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.57563094
497-methylguanosine mRNA capping (GO:0006370)3.57500774
50establishment of integrated proviral latency (GO:0075713)3.56739725
51RNA catabolic process (GO:0006401)3.55524203
52DNA strand elongation involved in DNA replication (GO:0006271)3.55043654
537-methylguanosine RNA capping (GO:0009452)3.53180787
54RNA capping (GO:0036260)3.53180787
55purine nucleoside triphosphate biosynthetic process (GO:0009145)3.50930173
56pseudouridine synthesis (GO:0001522)3.50322857
57purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.47634380
58telomere maintenance via recombination (GO:0000722)3.47232866
59mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.45876696
60rRNA metabolic process (GO:0016072)3.45126113
61DNA strand elongation (GO:0022616)3.42956604
62respiratory chain complex IV assembly (GO:0008535)3.41731313
63positive regulation of ligase activity (GO:0051351)3.41530228
64negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.40584724
65negative regulation of ligase activity (GO:0051352)3.40584724
66oxidative phosphorylation (GO:0006119)3.38425355
67formation of translation preinitiation complex (GO:0001731)3.37311749
68mitochondrial respiratory chain complex assembly (GO:0033108)3.37067412
69hydrogen ion transmembrane transport (GO:1902600)3.36924108
70GTP biosynthetic process (GO:0006183)3.36018832
71transcription-coupled nucleotide-excision repair (GO:0006283)3.35099175
72antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.33304166
73positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.33144309
74regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.30601900
75DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.29746482
76chromatin remodeling at centromere (GO:0031055)3.29298642
77spliceosomal snRNP assembly (GO:0000387)3.29106249
78regulation of ubiquitin-protein transferase activity (GO:0051438)3.22825693
79signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.22770417
80intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.22770417
81cullin deneddylation (GO:0010388)3.22196444
82mitochondrial transport (GO:0006839)3.21838445
83ribonucleoside triphosphate biosynthetic process (GO:0009201)3.21497743
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.21330641
85signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.20800331
86signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.20800331
87signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.20800331
88regulation of cellular amino acid metabolic process (GO:0006521)3.20339596
89DNA damage response, detection of DNA damage (GO:0042769)3.19147382
90tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.18390159
91RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.18390159
92spliceosomal complex assembly (GO:0000245)3.16329627
93respiratory electron transport chain (GO:0022904)3.15352941
94nucleotide-excision repair, DNA gap filling (GO:0006297)3.13863022
95protein neddylation (GO:0045116)3.12947298
96antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.12679947
97rRNA methylation (GO:0031167)3.11987467
98regulation of ligase activity (GO:0051340)3.10813509
99signal transduction involved in DNA damage checkpoint (GO:0072422)3.10217520
100signal transduction involved in DNA integrity checkpoint (GO:0072401)3.10217520
101mitotic recombination (GO:0006312)3.09353500
102electron transport chain (GO:0022900)3.08861193
103signal transduction involved in cell cycle checkpoint (GO:0072395)3.06524918
104transcription elongation from RNA polymerase I promoter (GO:0006362)3.06149734
105establishment of viral latency (GO:0019043)3.05632564
106UTP biosynthetic process (GO:0006228)3.04166615
107protein targeting to mitochondrion (GO:0006626)3.03331396
108telomere maintenance via telomere lengthening (GO:0010833)3.01249980
109guanosine-containing compound biosynthetic process (GO:1901070)2.99741428
110histone mRNA metabolic process (GO:0008334)2.99529222
111termination of RNA polymerase I transcription (GO:0006363)2.99484786
112CENP-A containing nucleosome assembly (GO:0034080)2.98681624
113DNA replication initiation (GO:0006270)2.97124382
114L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.95809210
115transcription from RNA polymerase I promoter (GO:0006360)2.94718637
116peptidyl-histidine modification (GO:0018202)2.93886032
117establishment of protein localization to mitochondrion (GO:0072655)2.93576509
118pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.92933938
119regulation of mitochondrial translation (GO:0070129)2.92579682
120cytochrome complex assembly (GO:0017004)2.89535341

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.38075976
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.37870957
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.33915754
4E2F7_22180533_ChIP-Seq_HELA_Human4.31524783
5GABP_17652178_ChIP-ChIP_JURKAT_Human4.19655101
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.02065071
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.72496832
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.63777936
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.50260961
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.40387069
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.13129002
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.06262856
13MYC_18358816_ChIP-ChIP_MESCs_Mouse3.03008791
14* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.96250614
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.92213885
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.88870721
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.83604582
18VDR_23849224_ChIP-Seq_CD4+_Human2.78440592
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.76263474
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69854429
21XRN2_22483619_ChIP-Seq_HELA_Human2.55592802
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.52565661
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.42031024
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.35604204
25DCP1A_22483619_ChIP-Seq_HELA_Human2.33208858
26FOXP3_21729870_ChIP-Seq_TREG_Human2.32205304
27SRF_21415370_ChIP-Seq_HL-1_Mouse2.30276417
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.18308059
29* TTF2_22483619_ChIP-Seq_HELA_Human2.15413419
30THAP11_20581084_ChIP-Seq_MESCs_Mouse2.11816452
31ELK1_19687146_ChIP-ChIP_HELA_Human2.11386518
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.11369292
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.05919883
34* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.04937883
35TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.04121029
36HOXB4_20404135_ChIP-ChIP_EML_Mouse2.01668438
37GABP_19822575_ChIP-Seq_HepG2_Human2.00781671
38NELFA_20434984_ChIP-Seq_ESCs_Mouse1.99811787
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.98253226
40PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.90002437
41CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.84516151
42ERG_20887958_ChIP-Seq_HPC-7_Mouse1.81278340
43SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.77797804
44ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73018428
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.69949651
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64928662
47NOTCH1_21737748_ChIP-Seq_TLL_Human1.64520430
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.57760221
49FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.56717124
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.54296831
51* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.51610578
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51326634
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49738275
54CIITA_25753668_ChIP-Seq_RAJI_Human1.48003818
55ELK1_22589737_ChIP-Seq_MCF10A_Human1.47845353
56MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.47244723
57MYC_18940864_ChIP-ChIP_HL60_Human1.40988013
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40408716
59BP1_19119308_ChIP-ChIP_Hs578T_Human1.38904991
60MYCN_18555785_ChIP-Seq_MESCs_Mouse1.35806878
61CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.35287327
62* SPI1_23547873_ChIP-Seq_NB4_Human1.34788498
63HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.29171817
64FOXM1_23109430_ChIP-Seq_U2OS_Human1.28746115
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26318469
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24284027
67IRF8_22096565_ChIP-ChIP_GC-B_Human1.18523060
68E2F1_21310950_ChIP-Seq_MCF-7_Human1.14136236
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13976826
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13556249
71IRF1_19129219_ChIP-ChIP_H3396_Human1.12857405
72* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12742830
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12715393
74* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.11249172
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11097134
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.08793154
77DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.07283640
78TP63_19390658_ChIP-ChIP_HaCaT_Human1.04604482
79KDM5A_27292631_Chip-Seq_BREAST_Human1.04088846
80PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03765496
81SCL_19346495_ChIP-Seq_HPC-7_Human1.03149025
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.02604610
83TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.02422013
84STAT4_19710469_ChIP-ChIP_TH1__Mouse1.02164542
85CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.01992012
86CTCF_18555785_ChIP-Seq_MESCs_Mouse1.00397280
87ZNF263_19887448_ChIP-Seq_K562_Human0.98745944
88MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.98619481
89CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98419267
90ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.97430939
91POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.97342553
92* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95243816
93* ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94157792
94FOXP1_21924763_ChIP-Seq_HESCs_Human0.93010682
95E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92121334
96MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.87773302
97IRF8_21731497_ChIP-ChIP_J774_Mouse0.87512425
98SOX2_16153702_ChIP-ChIP_HESCs_Human0.86484641
99NANOG_16153702_ChIP-ChIP_HESCs_Human0.86173634
100PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.86064702
101LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.85213640
102STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84501856
103HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83925846
104ELF5_23300383_ChIP-Seq_T47D_Human0.82671158
105SOX17_20123909_ChIP-Seq_XEN_Mouse0.81486536
106SOX2_18692474_ChIP-Seq_MEFs_Mouse0.80736131
107TFEB_21752829_ChIP-Seq_HELA_Human0.79723601
108SRY_22984422_ChIP-ChIP_TESTIS_Rat0.78527140
109* VDR_21846776_ChIP-Seq_THP-1_Human0.78081409
110AR_21909140_ChIP-Seq_LNCAP_Human0.78018136
111OCT4_18692474_ChIP-Seq_MEFs_Mouse0.75967533
112GATA1_22383799_ChIP-Seq_G1ME_Mouse0.75197593
113CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74646186
114* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.74150362
115ESR1_15608294_ChIP-ChIP_MCF-7_Human0.73618264
116* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.72090010
117EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.71352552
118KLF4_18555785_ChIP-Seq_MESCs_Mouse0.70703753
119SOX2_18555785_ChIP-Seq_MESCs_Mouse0.70290296
120PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.70037098

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.65205896
2MP0003693_abnormal_embryo_hatching3.87796999
3MP0003806_abnormal_nucleotide_metabolis3.29280599
4MP0008057_abnormal_DNA_replication3.13148264
5MP0004957_abnormal_blastocyst_morpholog3.06957595
6MP0010030_abnormal_orbit_morphology3.01759488
7MP0010094_abnormal_chromosome_stability2.80148948
8MP0008058_abnormal_DNA_repair2.74743808
9MP0003077_abnormal_cell_cycle2.63240275
10MP0006292_abnormal_olfactory_placode2.54832011
11MP0008007_abnormal_cellular_replicative2.33773838
12MP0002396_abnormal_hematopoietic_system2.30668473
13MP0001986_abnormal_taste_sensitivity2.28853201
14MP0003111_abnormal_nucleus_morphology2.22175318
15MP0001529_abnormal_vocalization2.19961478
16MP0001835_abnormal_antigen_presentation2.13757409
17MP0003786_premature_aging2.10312543
18MP0008932_abnormal_embryonic_tissue2.00655287
19MP0005174_abnormal_tail_pigmentation2.00580901
20MP0005671_abnormal_response_to1.98337586
21MP0001905_abnormal_dopamine_level1.90644037
22MP0003763_abnormal_thymus_physiology1.90207841
23MP0009333_abnormal_splenocyte_physiolog1.87785942
24MP0009785_altered_susceptibility_to1.87240087
25MP0005075_abnormal_melanosome_morpholog1.86363836
26MP0002132_abnormal_respiratory_system1.85249122
27MP0001293_anophthalmia1.77443250
28MP0003724_increased_susceptibility_to1.77247978
29MP0002938_white_spotting1.76839233
30MP0002148_abnormal_hypersensitivity_rea1.69331885
31MP0002638_abnormal_pupillary_reflex1.68238769
32MP0000490_abnormal_crypts_of1.60729908
33MP0003186_abnormal_redox_activity1.58118496
34MP0003941_abnormal_skin_development1.57046174
35MP0003718_maternal_effect1.52687928
36MP0002398_abnormal_bone_marrow1.50948207
37MP0005409_darkened_coat_color1.50349939
38MP0002095_abnormal_skin_pigmentation1.49685754
39MP0001800_abnormal_humoral_immune1.49423791
40MP0002163_abnormal_gland_morphology1.48949150
41MP0002234_abnormal_pharynx_morphology1.47735864
42MP0005025_abnormal_response_to1.47714456
43MP0000685_abnormal_immune_system1.45542051
44MP0005000_abnormal_immune_tolerance1.39213184
45MP0000372_irregular_coat_pigmentation1.38340236
46MP0000689_abnormal_spleen_morphology1.38221742
47MP0006036_abnormal_mitochondrial_physio1.37024954
48MP0002723_abnormal_immune_serum1.36661593
49MP0001188_hyperpigmentation1.35646498
50MP0002722_abnormal_immune_system1.35591450
51MP0002420_abnormal_adaptive_immunity1.35444761
52MP0001545_abnormal_hematopoietic_system1.35008292
53MP0005397_hematopoietic_system_phenotyp1.35008292
54MP0004808_abnormal_hematopoietic_stem1.34583052
55MP0001819_abnormal_immune_cell1.32900759
56MP0002452_abnormal_antigen_presenting1.30750634
57MP0005084_abnormal_gallbladder_morpholo1.30606911
58MP0002653_abnormal_ependyma_morphology1.29024845
59MP0000716_abnormal_immune_system1.28419873
60MP0003315_abnormal_perineum_morphology1.27358676
61MP0008995_early_reproductive_senescence1.26445450
62MP0001853_heart_inflammation1.25183501
63MP0000537_abnormal_urethra_morphology1.24647341
64MP0002429_abnormal_blood_cell1.23707372
65MP0004381_abnormal_hair_follicle1.22329494
66MP0005379_endocrine/exocrine_gland_phen1.21929438
67MP0003136_yellow_coat_color1.21420650
68MP0002736_abnormal_nociception_after1.19743135
69MP0000703_abnormal_thymus_morphology1.17912792
70MP0002405_respiratory_system_inflammati1.11326415
71MP0003123_paternal_imprinting1.07661066
72MP0000313_abnormal_cell_death1.07159751
73MP0002019_abnormal_tumor_incidence1.06409985
74MP0006035_abnormal_mitochondrial_morpho1.04982516
75MP0000465_gastrointestinal_hemorrhage1.04597364
76MP0000015_abnormal_ear_pigmentation1.04529952
77MP0003436_decreased_susceptibility_to1.03988414
78MP0005464_abnormal_platelet_physiology1.03255876
79MP0004147_increased_porphyrin_level1.03157105
80MP0001881_abnormal_mammary_gland1.03046169
81MP0001346_abnormal_lacrimal_gland1.02133099
82MP0005387_immune_system_phenotype1.01647369
83MP0001790_abnormal_immune_system1.01647369
84MP0008877_abnormal_DNA_methylation1.00455760
85MP0000631_abnormal_neuroendocrine_gland0.99898851
86MP0002277_abnormal_respiratory_mucosa0.99898007
87MP0005408_hypopigmentation0.98973677
88MP0004142_abnormal_muscle_tone0.97970682
89MP0000653_abnormal_sex_gland0.97814838
90MP0001697_abnormal_embryo_size0.97761096
91MP0001730_embryonic_growth_arrest0.97652950
92MP0003866_abnormal_defecation0.97162317
93MP0001929_abnormal_gametogenesis0.94492238
94MP0009697_abnormal_copulation0.92961976
95MP0006054_spinal_hemorrhage0.92935253
96MP0002419_abnormal_innate_immunity0.92885455
97MP0000566_synostosis0.92194225
98MP0002837_dystrophic_cardiac_calcinosis0.91045639
99MP0001919_abnormal_reproductive_system0.90515768
100MP0002751_abnormal_autonomic_nervous0.90432099
101MP0002102_abnormal_ear_morphology0.89656597
102MP0005394_taste/olfaction_phenotype0.89537257
103MP0005499_abnormal_olfactory_system0.89537257
104MP0005389_reproductive_system_phenotype0.88433179
105MP0000350_abnormal_cell_proliferation0.87856652
106MP0006276_abnormal_autonomic_nervous0.87610867
107MP0003938_abnormal_ear_development0.86946707
108MP0003567_abnormal_fetal_cardiomyocyte0.86899338
109MP0002697_abnormal_eye_size0.86823834
110MP0001286_abnormal_eye_development0.86730227
111MP0008875_abnormal_xenobiotic_pharmacok0.86007404
112MP0005501_abnormal_skin_physiology0.85529745
113MP0002210_abnormal_sex_determination0.83756731
114MP0005645_abnormal_hypothalamus_physiol0.82960786
115MP0001764_abnormal_homeostasis0.81365282
116MP0002085_abnormal_embryonic_tissue0.80840261
117MP0002090_abnormal_vision0.80067448
118MP0000858_altered_metastatic_potential0.79350786
119MP0003937_abnormal_limbs/digits/tail_de0.78877289
120MP0005332_abnormal_amino_acid0.77829901
121MP0004133_heterotaxia0.76290001
122MP0000681_abnormal_thyroid_gland0.76276950
123MP0005253_abnormal_eye_physiology0.75465843
124MP0006072_abnormal_retinal_apoptosis0.75275954
125MP0002080_prenatal_lethality0.75181649
126MP0005636_abnormal_mineral_homeostasis0.74928665
127MP0008789_abnormal_olfactory_epithelium0.74077351
128MP0001845_abnormal_inflammatory_respons0.72244557
129MP0008872_abnormal_physiological_respon0.71719348
130MP0000358_abnormal_cell_content/0.71478928
131MP0004019_abnormal_vitamin_homeostasis0.71460618
132MP0002160_abnormal_reproductive_system0.71226455
133MP0000647_abnormal_sebaceous_gland0.71105566
134MP0002111_abnormal_tail_morphology0.70631652
135MP0001119_abnormal_female_reproductive0.70598589
136MP0003656_abnormal_erythrocyte_physiolo0.70329324
137MP0000762_abnormal_tongue_morphology0.69178129
138MP0000049_abnormal_middle_ear0.69086416
139MP0003011_delayed_dark_adaptation0.68965629
140MP0005377_hearing/vestibular/ear_phenot0.66341310
141MP0003878_abnormal_ear_physiology0.66341310
142MP0005551_abnormal_eye_electrophysiolog0.65977776
143MP0001145_abnormal_male_reproductive0.65637263
144MP0002006_tumorigenesis0.65632729
145MP0001727_abnormal_embryo_implantation0.65483629
146MP0002796_impaired_skin_barrier0.64778367
147MP0005410_abnormal_fertilization0.63863925
148MP0002233_abnormal_nose_morphology0.63611499
149MP0003283_abnormal_digestive_organ0.63591412

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.67425225
2Abnormal number of erythroid precursors (HP:0012131)6.25619920
3Reticulocytopenia (HP:0001896)5.52597000
4Macrocytic anemia (HP:0001972)4.41728914
5Mitochondrial inheritance (HP:0001427)4.33598039
6Pallor (HP:0000980)4.24085700
7Acute necrotizing encephalopathy (HP:0006965)4.18256355
8Increased hepatocellular lipid droplets (HP:0006565)4.14863884
9Hepatocellular necrosis (HP:0001404)4.11594461
103-Methylglutaconic aciduria (HP:0003535)4.11281223
11Aplastic anemia (HP:0001915)4.03019839
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.82002341
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.82002341
14Abnormal mitochondria in muscle tissue (HP:0008316)3.73056892
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.72101941
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.65070410
17Increased CSF lactate (HP:0002490)3.64508573
18Renal Fanconi syndrome (HP:0001994)3.59917875
19Exertional dyspnea (HP:0002875)3.58491725
20Lipid accumulation in hepatocytes (HP:0006561)3.55498007
21Hepatic necrosis (HP:0002605)3.46722554
22Progressive macrocephaly (HP:0004481)3.34371901
23Acute encephalopathy (HP:0006846)3.16600665
24Type I transferrin isoform profile (HP:0003642)3.05992070
25Increased intramyocellular lipid droplets (HP:0012240)3.05457881
26Aplasia/Hypoplasia of the sacrum (HP:0008517)2.98748622
27Increased serum lactate (HP:0002151)2.94742607
28Birth length less than 3rd percentile (HP:0003561)2.91451687
29Respiratory difficulties (HP:0002880)2.75876982
30IgM deficiency (HP:0002850)2.75641751
31Testicular atrophy (HP:0000029)2.75328123
32Oral leukoplakia (HP:0002745)2.69434522
33Exercise intolerance (HP:0003546)2.66706190
34Lethargy (HP:0001254)2.56915036
35Thrombocytosis (HP:0001894)2.54929201
36Lactic acidosis (HP:0003128)2.49893615
3711 pairs of ribs (HP:0000878)2.47522112
38Microvesicular hepatic steatosis (HP:0001414)2.46767195
39Hypothermia (HP:0002045)2.42455825
40Increased muscle lipid content (HP:0009058)2.41804553
41Abnormality of the heme biosynthetic pathway (HP:0010472)2.39985701
42Type 2 muscle fiber atrophy (HP:0003554)2.37102597
43Methylmalonic aciduria (HP:0012120)2.36758437
44Methylmalonic acidemia (HP:0002912)2.36481946
45Muscle fiber atrophy (HP:0100295)2.34647841
46Degeneration of anterior horn cells (HP:0002398)2.34044196
47Abnormality of the anterior horn cell (HP:0006802)2.34044196
48Breast hypoplasia (HP:0003187)2.33369432
49Generalized aminoaciduria (HP:0002909)2.31789516
50Respiratory failure (HP:0002878)2.28991868
51Abnormality of renal resorption (HP:0011038)2.26098720
52Glycosuria (HP:0003076)2.25900798
53Abnormality of urine glucose concentration (HP:0011016)2.25900798
54Pancytopenia (HP:0001876)2.21676912
55Petechiae (HP:0000967)2.19434432
56Abnormality of methionine metabolism (HP:0010901)2.14363159
57Hyperphosphaturia (HP:0003109)2.12830658
58Rough bone trabeculation (HP:0100670)2.10203809
59Cerebral hypomyelination (HP:0006808)2.09330320
60Absent rod-and cone-mediated responses on ERG (HP:0007688)2.08106916
61Microretrognathia (HP:0000308)2.08019650
62Optic disc pallor (HP:0000543)2.06273123
63CNS demyelination (HP:0007305)2.04613625
64Premature graying of hair (HP:0002216)2.04474433
65Reduced antithrombin III activity (HP:0001976)2.03600745
66Elevated erythrocyte sedimentation rate (HP:0003565)2.03487806
67Absent thumb (HP:0009777)2.03212785
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.03025288
69Abnormal protein N-linked glycosylation (HP:0012347)2.03025288
70Abnormal protein glycosylation (HP:0012346)2.03025288
71Abnormal glycosylation (HP:0012345)2.03025288
72Septo-optic dysplasia (HP:0100842)2.01315850
73X-linked dominant inheritance (HP:0001423)1.98280546
74Pancreatic fibrosis (HP:0100732)1.95905766
75Depressed nasal ridge (HP:0000457)1.92907644
76Emotional lability (HP:0000712)1.92065250
77Panhypogammaglobulinemia (HP:0003139)1.91917989
78Abnormality of the preputium (HP:0100587)1.91347097
79Parakeratosis (HP:0001036)1.90875157
80Cerebral edema (HP:0002181)1.88601264
81Leukodystrophy (HP:0002415)1.88043948
82True hermaphroditism (HP:0010459)1.86866353
83Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.86860346
84Abnormality of alanine metabolism (HP:0010916)1.86860346
85Hyperalaninemia (HP:0003348)1.86860346
86Myelodysplasia (HP:0002863)1.85810927
87Chromsome breakage (HP:0040012)1.85457959
88Megaloblastic anemia (HP:0001889)1.85373588
89IgG deficiency (HP:0004315)1.84764646
90Poor head control (HP:0002421)1.84526573
91Amniotic constriction ring (HP:0009775)1.83465439
92Abnormality of placental membranes (HP:0011409)1.83465439
93Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.79520980
94Abnormality of secondary sexual hair (HP:0009888)1.79060401
95Abnormality of the axillary hair (HP:0100134)1.79060401
96Severe visual impairment (HP:0001141)1.78682664
97Abnormality of dicarboxylic acid metabolism (HP:0010995)1.78011950
98Dicarboxylic aciduria (HP:0003215)1.78011950
99Triphalangeal thumb (HP:0001199)1.77613105
100Pancreatic cysts (HP:0001737)1.77009013
101Hypoplasia of the pons (HP:0012110)1.76716929
102Recurrent abscess formation (HP:0002722)1.75668627
103Neutropenia (HP:0001875)1.74879024
104Abnormal lung lobation (HP:0002101)1.74374532
105Concave nail (HP:0001598)1.74194956
106Hyperglycinemia (HP:0002154)1.74104941
107Aplasia/hypoplasia of the uterus (HP:0008684)1.74058697
108Carpal bone hypoplasia (HP:0001498)1.73954502
109Bone marrow hypocellularity (HP:0005528)1.73013276
110Absent septum pellucidum (HP:0001331)1.72395830
111Abnormality of serum amino acid levels (HP:0003112)1.72290812
112Abnormality of aspartate family amino acid metabolism (HP:0010899)1.71741927
113Meckel diverticulum (HP:0002245)1.70172034
114Abnormal trabecular bone morphology (HP:0100671)1.70014386
115Abnormality of the pons (HP:0007361)1.69854232
116Cleft eyelid (HP:0000625)1.67647725
117Blindness (HP:0000618)1.67597768
118Chronic otitis media (HP:0000389)1.67427117
119Progressive muscle weakness (HP:0003323)1.66919066
120Multiple enchondromatosis (HP:0005701)1.66133471
121Sparse eyelashes (HP:0000653)1.65738346
122Lymphoma (HP:0002665)1.65713149
123Abnormal urine phosphate concentration (HP:0012599)1.65490306
124Pulmonary fibrosis (HP:0002206)1.64150623
125Sclerocornea (HP:0000647)1.64113389
126Chromosomal breakage induced by crosslinking agents (HP:0003221)1.63964636
127Renal tubular dysfunction (HP:0000124)1.63510819
128Abnormality of aromatic amino acid family metabolism (HP:0004338)1.63023404
129Abnormality of glycolysis (HP:0004366)1.62638207
130Increased serum pyruvate (HP:0003542)1.62638207
131Patellar aplasia (HP:0006443)1.62503515
132Asplenia (HP:0001746)1.62462535
133Congenital, generalized hypertrichosis (HP:0004540)1.62027188
134Colon cancer (HP:0003003)1.62008098
135Cellular immunodeficiency (HP:0005374)1.60232340
136Patchy hypopigmentation of hair (HP:0011365)1.59585596
137Molar tooth sign on MRI (HP:0002419)1.58602578
138Abnormality of midbrain morphology (HP:0002418)1.58602578
139Abnormality of the labia minora (HP:0012880)1.58069224
140Congenital ichthyosiform erythroderma (HP:0007431)1.56994062

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.66736290
2STK164.61910972
3NME23.95539917
4BUB13.92673032
5VRK13.04807012
6WEE12.84322132
7SRPK12.22742159
8MAP3K122.20240147
9PIM22.14456242
10TAF12.04778478
11TLK12.02198570
12EIF2AK11.91575187
13EIF2AK31.88406876
14MAP4K11.82035139
15PLK41.77419376
16MUSK1.73281938
17NME11.73266911
18BRSK21.70759029
19NEK11.70155656
20ACVR1B1.67023870
21IRAK41.66428449
22NUAK11.61747228
23CDK81.59858029
24TESK11.55358331
25MAPKAPK51.55201255
26MKNK11.55097226
27DYRK31.44230388
28TEC1.43232306
29CDC71.39367146
30TXK1.34833443
31TGFBR11.33887946
32TSSK61.29967324
33RPS6KB21.27763031
34BTK1.26553217
35ADRBK21.24552268
36CDK71.23795836
37TNIK1.23235981
38KIT1.22730360
39LIMK11.14672902
40CDK191.13785356
41MST41.13560416
42MKNK21.13341743
43BMPR1B1.11423006
44KDR1.10277508
45PBK1.09223889
46CCNB11.07153449
47RPS6KA51.04615615
48BLK0.98342451
49PLK10.97790293
50AURKB0.96976027
51TESK20.96760421
52GRK70.94770170
53PASK0.94380685
54RPS6KA40.93737646
55DAPK10.91895969
56MAP4K20.90057723
57PDK20.89454311
58DYRK20.88102608
59EIF2AK20.87628262
60PRKCI0.86758455
61BRSK10.85943269
62ATR0.83953137
63AURKA0.83952847
64SYK0.83273395
65IRAK30.83051559
66IKBKB0.83048247
67SMG10.82905370
68ZAK0.81699128
69MYLK0.81139939
70PAK40.79505635
71ZAP700.77042428
72EPHA20.76673949
73MAP3K110.76046452
74DAPK30.75564191
75CSNK2A10.72637132
76BRAF0.72582894
77LYN0.71743825
78LRRK20.71435768
79NEK20.71192995
80NLK0.69886295
81CSNK1G30.69439028
82PIM10.68432466
83SCYL20.67989797
84CSNK2A20.67818457
85BCKDK0.67038221
86IKBKE0.64965624
87PLK30.63701091
88YES10.63063422
89ILK0.62302843
90ABL20.62240689
91CSF1R0.62038432
92ARAF0.61738681
93FLT30.60640200
94MAPK150.58619251
95MAP2K70.57561815
96GRK10.56864533
97CHEK20.56640074
98WNK30.54338407
99TYK20.53322977
100LCK0.51592729
101TRIM280.51285394
102CSNK1G20.50967422
103CLK10.49591358
104MATK0.47667441
105JAK30.46328983
106CSNK1G10.45034424
107TTK0.44973475
108CSNK1A1L0.44473923
109MAPK40.44412547
110TAOK30.43733650
111MAPKAPK30.43693115
112PAK10.43268433
113TBK10.40356595
114CHEK10.39876503
115RPS6KA60.39508864
116SIK30.38865627
117MAPK130.38174181
118GRK60.35798205
119WNK40.35417083
120IRAK10.34251569
121RPS6KC10.33435129
122RPS6KL10.33435129
123STK40.32916641
124EPHB20.32514569
125ATM0.29598268
126CSNK1E0.28598193
127GRK50.27701584
128CSNK1A10.26612289
129STK240.25650363
130AKT20.25194340
131TAOK20.23188635
132INSRR0.22677384
133MAP3K90.21840638
134CDK90.21490816
135CAMK2G0.21183158

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.09144152
2Proteasome_Homo sapiens_hsa030503.99276069
3RNA polymerase_Homo sapiens_hsa030203.76887034
4DNA replication_Homo sapiens_hsa030303.63674470
5Oxidative phosphorylation_Homo sapiens_hsa001903.16708775
6Mismatch repair_Homo sapiens_hsa034303.06799641
7Parkinsons disease_Homo sapiens_hsa050122.90152608
8Protein export_Homo sapiens_hsa030602.87365175
9Pyrimidine metabolism_Homo sapiens_hsa002402.61674184
10Spliceosome_Homo sapiens_hsa030402.61571652
11Homologous recombination_Homo sapiens_hsa034402.55528153
12Nucleotide excision repair_Homo sapiens_hsa034202.45953391
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.37270533
14Base excision repair_Homo sapiens_hsa034102.35208375
15Huntingtons disease_Homo sapiens_hsa050162.22112704
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.92107678
17Alzheimers disease_Homo sapiens_hsa050101.91927141
18RNA degradation_Homo sapiens_hsa030181.85122881
19Basal transcription factors_Homo sapiens_hsa030221.75170262
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.74368682
21RNA transport_Homo sapiens_hsa030131.73558548
22Non-homologous end-joining_Homo sapiens_hsa034501.65856799
23Fanconi anemia pathway_Homo sapiens_hsa034601.58938783
24Purine metabolism_Homo sapiens_hsa002301.41423184
25Cell cycle_Homo sapiens_hsa041101.40265072
26Folate biosynthesis_Homo sapiens_hsa007901.33922364
27Sulfur relay system_Homo sapiens_hsa041221.26292762
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.26184072
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.25459573
30Primary immunodeficiency_Homo sapiens_hsa053401.21771109
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.13816781
32One carbon pool by folate_Homo sapiens_hsa006701.07011492
33Pyruvate metabolism_Homo sapiens_hsa006201.06293452
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.05835162
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.93450186
36Epstein-Barr virus infection_Homo sapiens_hsa051690.88257402
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87359954
38SNARE interactions in vesicular transport_Homo sapiens_hsa041300.84959600
39Sulfur metabolism_Homo sapiens_hsa009200.81686254
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81069234
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80938609
42p53 signaling pathway_Homo sapiens_hsa041150.78394320
43Arachidonic acid metabolism_Homo sapiens_hsa005900.75536818
44Propanoate metabolism_Homo sapiens_hsa006400.75239752
45Antigen processing and presentation_Homo sapiens_hsa046120.73849314
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72062048
47Herpes simplex infection_Homo sapiens_hsa051680.69367245
48Biosynthesis of amino acids_Homo sapiens_hsa012300.66920489
49Cardiac muscle contraction_Homo sapiens_hsa042600.65980627
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.65968906
51Allograft rejection_Homo sapiens_hsa053300.65940903
52Systemic lupus erythematosus_Homo sapiens_hsa053220.65791307
53Intestinal immune network for IgA production_Homo sapiens_hsa046720.65507863
54Carbon metabolism_Homo sapiens_hsa012000.64539252
55Collecting duct acid secretion_Homo sapiens_hsa049660.64211838
56Hematopoietic cell lineage_Homo sapiens_hsa046400.63255622
57Asthma_Homo sapiens_hsa053100.61412423
58Glutathione metabolism_Homo sapiens_hsa004800.60053757
59Selenocompound metabolism_Homo sapiens_hsa004500.59817852
60mRNA surveillance pathway_Homo sapiens_hsa030150.59710817
61Other glycan degradation_Homo sapiens_hsa005110.57520009
62Graft-versus-host disease_Homo sapiens_hsa053320.57457591
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.57073907
64Peroxisome_Homo sapiens_hsa041460.56188281
65Metabolic pathways_Homo sapiens_hsa011000.55567158
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.55121673
67N-Glycan biosynthesis_Homo sapiens_hsa005100.53025168
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.51361330
69Steroid biosynthesis_Homo sapiens_hsa001000.50414589
70Vitamin B6 metabolism_Homo sapiens_hsa007500.48380920
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47987021
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47548760
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.45869087
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45154980
75Measles_Homo sapiens_hsa051620.44486483
76Pentose phosphate pathway_Homo sapiens_hsa000300.44200841
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.44090189
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.43815625
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43411818
80Linoleic acid metabolism_Homo sapiens_hsa005910.43048403
81Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40994147
82Vitamin digestion and absorption_Homo sapiens_hsa049770.39990370
83Autoimmune thyroid disease_Homo sapiens_hsa053200.38715206
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.37396171
85Legionellosis_Homo sapiens_hsa051340.36615081
86Oocyte meiosis_Homo sapiens_hsa041140.36441475
87Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35749456
88Fatty acid elongation_Homo sapiens_hsa000620.35096167
89RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34622793
90Tyrosine metabolism_Homo sapiens_hsa003500.34614356
91Arginine and proline metabolism_Homo sapiens_hsa003300.33297797
92Fructose and mannose metabolism_Homo sapiens_hsa000510.33066207
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32324773
94Rheumatoid arthritis_Homo sapiens_hsa053230.31923712
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.31321442
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30689625
97Chemical carcinogenesis_Homo sapiens_hsa052040.29474714
98Sphingolipid metabolism_Homo sapiens_hsa006000.28271441
99Cyanoamino acid metabolism_Homo sapiens_hsa004600.28037113
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.27401826
101Regulation of autophagy_Homo sapiens_hsa041400.27363705
102Ether lipid metabolism_Homo sapiens_hsa005650.27083614
103Leishmaniasis_Homo sapiens_hsa051400.26605480
104Basal cell carcinoma_Homo sapiens_hsa052170.26466689
105Shigellosis_Homo sapiens_hsa051310.25738243
106Phototransduction_Homo sapiens_hsa047440.25432413
107Malaria_Homo sapiens_hsa051440.24764544
108Alcoholism_Homo sapiens_hsa050340.24179772
109Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.23969440
110Viral carcinogenesis_Homo sapiens_hsa052030.23775096
111Butanoate metabolism_Homo sapiens_hsa006500.23587530
112HTLV-I infection_Homo sapiens_hsa051660.21215356
113Pertussis_Homo sapiens_hsa051330.21130089
114beta-Alanine metabolism_Homo sapiens_hsa004100.20678345
115Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.20478868
116Nitrogen metabolism_Homo sapiens_hsa009100.20264388
117alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.19719786
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.18722985
119Jak-STAT signaling pathway_Homo sapiens_hsa046300.18709992
120Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18504296
121Phenylalanine metabolism_Homo sapiens_hsa003600.18049217
122Apoptosis_Homo sapiens_hsa042100.16768951
123Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.16136916
124Hepatitis B_Homo sapiens_hsa051610.14565419
125Type I diabetes mellitus_Homo sapiens_hsa049400.12914010
126Tryptophan metabolism_Homo sapiens_hsa003800.12712537
127Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.12330712
128Galactose metabolism_Homo sapiens_hsa000520.12005129
129Influenza A_Homo sapiens_hsa051640.11376335
130Primary bile acid biosynthesis_Homo sapiens_hsa001200.10212986
131Vibrio cholerae infection_Homo sapiens_hsa051100.10172430
132Fatty acid metabolism_Homo sapiens_hsa012120.09910252
133Retinol metabolism_Homo sapiens_hsa008300.09439448
134African trypanosomiasis_Homo sapiens_hsa051430.09420227
135Phagosome_Homo sapiens_hsa041450.09380581
136B cell receptor signaling pathway_Homo sapiens_hsa046620.08330173
137Caffeine metabolism_Homo sapiens_hsa002320.08099574
138Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.07998717
139Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.07909580
140Hedgehog signaling pathway_Homo sapiens_hsa043400.07510149
141Mineral absorption_Homo sapiens_hsa049780.06880640
142Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.05845897

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