TRGV3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine catabolic process (GO:0006216)6.71801697
2cytidine deamination (GO:0009972)6.71801697
3cytidine metabolic process (GO:0046087)6.71801697
4cellular response to interleukin-15 (GO:0071350)6.33815138
5pyrimidine ribonucleoside catabolic process (GO:0046133)6.24667898
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.18964829
7regulation of B cell receptor signaling pathway (GO:0050855)5.91607266
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.91568484
9negative T cell selection (GO:0043383)5.85896976
10positive regulation of gamma-delta T cell activation (GO:0046645)5.72094227
11DNA deamination (GO:0045006)5.65852004
12response to interleukin-15 (GO:0070672)5.65041393
13negative thymic T cell selection (GO:0045060)5.28469936
14antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.27676356
15negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.20972798
16negative regulation of cell killing (GO:0031342)5.20972798
17positive T cell selection (GO:0043368)4.98444137
18Arp2/3 complex-mediated actin nucleation (GO:0034314)4.95564056
19positive thymic T cell selection (GO:0045059)4.91315243
20antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.82805342
21antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.68265161
22regulation of gamma-delta T cell differentiation (GO:0045586)4.60175992
23antigen processing and presentation of endogenous antigen (GO:0019883)4.48546880
24T cell migration (GO:0072678)4.45230460
25mast cell activation (GO:0045576)4.41379029
26activated T cell proliferation (GO:0050798)4.34959821
27positive regulation of calcium-mediated signaling (GO:0050850)4.34866177
28regulation of gamma-delta T cell activation (GO:0046643)4.33983907
29response to interferon-beta (GO:0035456)4.24577016
30actin nucleation (GO:0045010)4.16811470
31thymic T cell selection (GO:0045061)4.13455919
32regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.11749478
33regulation of natural killer cell mediated immunity (GO:0002715)4.11749478
34positive regulation of natural killer cell mediated immunity (GO:0002717)4.11661450
35positive regulation of alpha-beta T cell proliferation (GO:0046641)4.10168603
36positive regulation of defense response to virus by host (GO:0002230)4.08491365
37positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.05411974
38T cell selection (GO:0045058)4.04260782
39positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.99778772
40regulation of alpha-beta T cell proliferation (GO:0046640)3.96790548
41regulation of leukocyte mediated cytotoxicity (GO:0001910)3.91623183
42T cell receptor signaling pathway (GO:0050852)3.88887925
43positive regulation of T cell mediated cytotoxicity (GO:0001916)3.82566370
44regulation of T cell mediated cytotoxicity (GO:0001914)3.81690628
45antigen receptor-mediated signaling pathway (GO:0050851)3.78760729
46mast cell activation involved in immune response (GO:0002279)3.76958695
47mast cell degranulation (GO:0043303)3.76958695
48positive regulation of B cell differentiation (GO:0045579)3.73394716
49hepatocyte apoptotic process (GO:0097284)3.71216164
50positive regulation of tolerance induction (GO:0002645)3.71087119
51regulation of B cell differentiation (GO:0045577)3.70665500
52regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.69517498
53immunoglobulin mediated immune response (GO:0016064)3.69502008
54negative regulation of viral genome replication (GO:0045071)3.68023468
55cellular response to interferon-beta (GO:0035458)3.65737791
56cellular defense response (GO:0006968)3.64680392
57regulation of T cell tolerance induction (GO:0002664)3.63307026
58positive regulation of cell killing (GO:0031343)3.63137523
59negative regulation of T cell apoptotic process (GO:0070233)3.61767358
60T cell costimulation (GO:0031295)3.57578747
61B cell receptor signaling pathway (GO:0050853)3.57052038
62regulation of regulatory T cell differentiation (GO:0045589)3.55371296
63regulation of cell killing (GO:0031341)3.53325663
64lymphocyte costimulation (GO:0031294)3.52964908
65negative regulation of T cell mediated immunity (GO:0002710)3.52381938
66regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.49556470
67regulation of interleukin-12 biosynthetic process (GO:0045075)3.48213342
68regulation of tolerance induction (GO:0002643)3.47208158
69regulation of lymphocyte chemotaxis (GO:1901623)3.41736943
70positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.28779967
71regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.23428057
72antigen processing and presentation via MHC class Ib (GO:0002475)3.21569995
73negative regulation of interleukin-12 production (GO:0032695)3.20563148
74leukocyte degranulation (GO:0043299)3.18543317
75regulation of calcium-mediated signaling (GO:0050848)3.17171878
76pyrimidine nucleoside catabolic process (GO:0046135)3.14611251
77regulation of defense response to virus by host (GO:0050691)3.03939598
78lymphocyte chemotaxis (GO:0048247)3.02267138
79leukocyte aggregation (GO:0070486)3.01910598
80regulation of T cell receptor signaling pathway (GO:0050856)3.01669826
81positive regulation of lymphocyte mediated immunity (GO:0002708)3.00572117
82interferon-gamma production (GO:0032609)2.97772091
83B cell mediated immunity (GO:0019724)2.97272709
84lymph node development (GO:0048535)2.95466833
85tolerance induction (GO:0002507)2.94241640
86negative regulation by host of viral transcription (GO:0043922)2.93479166
87positive regulation of interleukin-4 production (GO:0032753)2.92951332
88regulation of isotype switching to IgG isotypes (GO:0048302)2.92736385
89negative regulation of lymphocyte mediated immunity (GO:0002707)2.91549612
90positive regulation of humoral immune response (GO:0002922)2.89910576
91positive regulation of lymphocyte migration (GO:2000403)2.88865179
92regulation of interleukin-2 biosynthetic process (GO:0045076)2.88682745
93positive regulation of T cell mediated immunity (GO:0002711)2.87413426
94lymphocyte migration (GO:0072676)2.87077360
95chemokine-mediated signaling pathway (GO:0070098)2.85489429
96positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.82699449
97natural killer cell activation (GO:0030101)2.78454795
98negative regulation of leukocyte mediated immunity (GO:0002704)2.77269078
99cellular response to type I interferon (GO:0071357)2.76867908
100type I interferon signaling pathway (GO:0060337)2.76867908

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.51374468
2IRF8_22096565_ChIP-ChIP_GC-B_Human6.33668663
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.97397415
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.64655540
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.49319340
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.70650807
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.55365427
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.52907547
9RUNX_20019798_ChIP-Seq_JUKART_Human3.34119416
10MYB_26560356_Chip-Seq_TH2_Human3.19118751
11STAT4_19710469_ChIP-ChIP_TH1__Mouse2.96431230
12STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.93355008
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.77586634
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.61779214
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.50652946
16GATA3_27048872_Chip-Seq_THYMUS_Human2.29548453
17MYB_26560356_Chip-Seq_TH1_Human2.28513693
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.24973675
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.23597687
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.13181247
21GATA3_26560356_Chip-Seq_TH2_Human2.12032521
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.02173936
23MAF_26560356_Chip-Seq_TH1_Human2.01751566
24SPI1_23547873_ChIP-Seq_NB4_Human1.99949963
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.95808281
26SCL_19346495_ChIP-Seq_HPC-7_Human1.93986684
27UTX_26944678_Chip-Seq_JUKART_Human1.92189757
28MAF_26560356_Chip-Seq_TH2_Human1.74022192
29MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.70032950
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67730592
31MYB_21317192_ChIP-Seq_ERMYB_Mouse1.67426557
32LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.67215670
33E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.58893465
34NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.56307689
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.51400248
36SMAD_19615063_ChIP-ChIP_OVARY_Human1.50228729
37LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.50227359
38SPI1_23127762_ChIP-Seq_K562_Human1.50098219
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.48649079
40RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.40160648
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.34072226
42GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.31644037
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.30596701
44EGR1_23403033_ChIP-Seq_LIVER_Mouse1.30495495
45RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.28778507
46VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.23430863
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22446774
48VDR_23849224_ChIP-Seq_CD4+_Human1.21456160
49GATA1_22025678_ChIP-Seq_K562_Human1.18011675
50PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14003823
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09602506
52VDR_24763502_ChIP-Seq_THP-1_Human1.08891865
53CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07047571
54BCL6_27268052_Chip-Seq_Bcells_Human1.06710768
55VDR_22108803_ChIP-Seq_LS180_Human1.06666556
56CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05923366
57TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05319202
58CIITA_25753668_ChIP-Seq_RAJI_Human1.04241223
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.03240857
60VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01162136
61CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.01011509
62GATA3_26560356_Chip-Seq_TH1_Human1.00502044
63VDR_24787735_ChIP-Seq_THP-1_Human1.00383343
64EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.00064486
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.97498546
66Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.96915597
67SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96657123
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96365923
69SPI1_20517297_ChIP-Seq_HL60_Human0.96309910
70RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93913153
71HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92771119
72PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92596863
73STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.91548734
74CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.90960359
75SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.90697119
76FOXP3_21729870_ChIP-Seq_TREG_Human0.90106091
77GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90014545
78FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89451585
79PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89340568
80SMRT_27268052_Chip-Seq_Bcells_Human0.89129869
81RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88612952
82BCOR_27268052_Chip-Seq_Bcells_Human0.87072087
83SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86591319
84PU_27001747_Chip-Seq_BMDM_Mouse0.85615625
85GATA1_19941827_ChIP-Seq_MEL_Mouse0.83679869
86GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.83005695
87CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82448719
88MYC_22102868_ChIP-Seq_BL_Human0.79786577
89CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78571250
90BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74833778
91GATA2_21666600_ChIP-Seq_HMVEC_Human0.73576193
92GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72461526
93PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.71262970
94P300_27268052_Chip-Seq_Bcells_Human0.70983313
95NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.70794566
96FOXA1_21572438_ChIP-Seq_LNCaP_Human0.70077581
97TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.69180175
98GATA3_21878914_ChIP-Seq_MCF-7_Human0.68930404
99VDR_21846776_ChIP-Seq_THP-1_Human0.67317418
100TAF2_19829295_ChIP-Seq_ESCs_Human0.67192102

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.68905041
2MP0001835_abnormal_antigen_presentation4.71279534
3MP0003763_abnormal_thymus_physiology4.12088744
4MP0000685_abnormal_immune_system3.36394064
5MP0001800_abnormal_humoral_immune3.31860830
6MP0003724_increased_susceptibility_to3.19838553
7MP0009785_altered_susceptibility_to3.12558940
8MP0005000_abnormal_immune_tolerance3.08864366
9MP0005387_immune_system_phenotype2.93188120
10MP0001790_abnormal_immune_system2.93188120
11MP0002723_abnormal_immune_serum2.84981494
12MP0002420_abnormal_adaptive_immunity2.79212357
13MP0005025_abnormal_response_to2.75445162
14MP0003436_decreased_susceptibility_to2.75374615
15MP0001819_abnormal_immune_cell2.74402471
16MP0002148_abnormal_hypersensitivity_rea2.73869114
17MP0002452_abnormal_antigen_presenting2.59067690
18MP0002419_abnormal_innate_immunity2.43979401
19MP0002166_altered_tumor_susceptibility2.43253261
20MP0002398_abnormal_bone_marrow2.24829203
21MP0000716_abnormal_immune_system2.23803742
22MP0000703_abnormal_thymus_morphology2.17914006
23MP0003866_abnormal_defecation2.15535001
24MP0002405_respiratory_system_inflammati2.06619141
25MP0002138_abnormal_hepatobiliary_system2.03218334
26MP0000689_abnormal_spleen_morphology1.96849715
27MP0002722_abnormal_immune_system1.91631172
28MP0009333_abnormal_splenocyte_physiolog1.89633693
29MP0006082_CNS_inflammation1.87753630
30MP0010155_abnormal_intestine_physiology1.83823195
31MP0004381_abnormal_hair_follicle1.80821862
32MP0001853_heart_inflammation1.78713258
33MP0004947_skin_inflammation1.75787052
34MP0001845_abnormal_inflammatory_respons1.74609330
35MP0002429_abnormal_blood_cell1.70555366
36MP0005464_abnormal_platelet_physiology1.67697795
37MP0002006_tumorigenesis1.63929272
38MP0003806_abnormal_nucleotide_metabolis1.63299016
39MP0003300_gastrointestinal_ulcer1.62379711
40MP0001533_abnormal_skeleton_physiology1.49068066
41MP0005075_abnormal_melanosome_morpholog1.45261099
42MP0000569_abnormal_digit_pigmentation1.43099236
43MP0009764_decreased_sensitivity_to1.36533205
44MP0008469_abnormal_protein_level1.33691361
45MP0005174_abnormal_tail_pigmentation1.18446696
46MP0003183_abnormal_peptide_metabolism1.15944576
47MP0009763_increased_sensitivity_to1.14379508
48MP0002998_abnormal_bone_remodeling1.13990649
49MP0003045_fibrosis1.13464456
50MP0001873_stomach_inflammation1.11912954
51MP0001501_abnormal_sleep_pattern1.11724832
52MP0002277_abnormal_respiratory_mucosa1.09459441
53MP0009765_abnormal_xenobiotic_induced1.04702323
54MP0000858_altered_metastatic_potential1.02603442
55MP0005377_hearing/vestibular/ear_phenot1.00192590
56MP0003878_abnormal_ear_physiology1.00192590
57MP0002933_joint_inflammation0.99215742
58MP0002837_dystrophic_cardiac_calcinosis0.84468081
59MP0000465_gastrointestinal_hemorrhage0.84092839
60MP0000604_amyloidosis0.82999498
61MP0003448_altered_tumor_morphology0.81020219
62MP0002132_abnormal_respiratory_system0.80805883
63MP0002009_preneoplasia0.79485304
64MP0008872_abnormal_physiological_respon0.78983365
65MP0004036_abnormal_muscle_relaxation0.78238367
66MP0005167_abnormal_blood-brain_barrier0.77673923
67MP0004084_abnormal_cardiac_muscle0.75980723
68MP0005310_abnormal_salivary_gland0.74949949
69MP0002736_abnormal_nociception_after0.69011955
70MP0002102_abnormal_ear_morphology0.67876301
71MP0000015_abnormal_ear_pigmentation0.65815882
72MP0001851_eye_inflammation0.65582065
73MP0003172_abnormal_lysosome_physiology0.64689955
74MP0005390_skeleton_phenotype0.63785162
75MP0002019_abnormal_tumor_incidence0.63273880
76MP0008057_abnormal_DNA_replication0.62612208
77MP0009643_abnormal_urine_homeostasis0.62009278
78MP0002136_abnormal_kidney_physiology0.60989519
79MP0002396_abnormal_hematopoietic_system0.60724546
80MP0001765_abnormal_ion_homeostasis0.60710526
81MP0003795_abnormal_bone_structure0.59809202
82MP0003303_peritoneal_inflammation0.58167072
83MP0002163_abnormal_gland_morphology0.56444062
84MP0002877_abnormal_melanocyte_morpholog0.56151877
85MP0001986_abnormal_taste_sensitivity0.56002892
86MP0005166_decreased_susceptibility_to0.55845794
87MP0000920_abnormal_myelination0.53769860
88MP0000249_abnormal_blood_vessel0.52157479
89MP0002693_abnormal_pancreas_physiology0.51305808
90MP0003195_calcinosis0.49553995
91MP0008873_increased_physiological_sensi0.49425081
92MP0000343_altered_response_to0.49105194
93MP0002876_abnormal_thyroid_physiology0.47207186
94MP0000372_irregular_coat_pigmentation0.47094017
95MP0006035_abnormal_mitochondrial_morpho0.46718064
96MP0001968_abnormal_touch/_nociception0.46581552
97MP0003690_abnormal_glial_cell0.46274677
98MP0005645_abnormal_hypothalamus_physiol0.45214259
99MP0004885_abnormal_endolymph0.44139491
100MP0003075_altered_response_to0.43939132

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)6.45448991
2Recurrent cutaneous fungal infections (HP:0011370)5.99066066
3Chronic mucocutaneous candidiasis (HP:0002728)5.99066066
4Abnormality of T cell number (HP:0011839)5.85575401
5Severe combined immunodeficiency (HP:0004430)5.37676448
6Abnormality of T cells (HP:0002843)5.29922537
7Panhypogammaglobulinemia (HP:0003139)5.26417655
8IgG deficiency (HP:0004315)5.22128152
9Elevated erythrocyte sedimentation rate (HP:0003565)5.14933468
10Recurrent fungal infections (HP:0002841)5.00403864
11Abnormal delayed hypersensitivity skin test (HP:0002963)4.97995578
12Agammaglobulinemia (HP:0004432)4.56629572
13Encephalitis (HP:0002383)4.37688874
14Combined immunodeficiency (HP:0005387)4.32754905
15Abnormality of eosinophils (HP:0001879)4.11773614
16Recurrent bronchitis (HP:0002837)4.10489540
17Abnormality of T cell physiology (HP:0011840)4.03209773
18Thyroiditis (HP:0100646)4.01756512
19Recurrent viral infections (HP:0004429)3.95880528
20Stomatitis (HP:0010280)3.94884681
21Chronic diarrhea (HP:0002028)3.91724619
22Recurrent skin infections (HP:0001581)3.90579874
23Increased IgM level (HP:0003496)3.87309733
24Autoimmune hemolytic anemia (HP:0001890)3.73851184
25Meningitis (HP:0001287)3.70136189
26Eczematoid dermatitis (HP:0000976)3.67588345
27Myositis (HP:0100614)3.54079376
28Hypoplasia of the thymus (HP:0000778)3.53020313
29Retrobulbar optic neuritis (HP:0100654)3.48625232
30Optic neuritis (HP:0100653)3.48625232
31Vasculitis (HP:0002633)3.36048021
32Recurrent bacterial skin infections (HP:0005406)3.35953986
33Eosinophilia (HP:0001880)3.35830732
34Granulocytopenia (HP:0001913)3.32023884
35Leukocytosis (HP:0001974)3.31911479
36Pustule (HP:0200039)3.30991840
37Colitis (HP:0002583)3.13528400
38Orchitis (HP:0100796)3.12486445
39Recurrent abscess formation (HP:0002722)3.09827969
40Pulmonary infiltrates (HP:0002113)2.91683578
41Keratoconjunctivitis sicca (HP:0001097)2.91136593
42Hypoproteinemia (HP:0003075)2.88715997
43Abnormality of macrophages (HP:0004311)2.79901140
44Gastrointestinal infarctions (HP:0005244)2.72873125
45Keratoconjunctivitis (HP:0001096)2.66162913
46Lymphopenia (HP:0001888)2.62899620
47Mediastinal lymphadenopathy (HP:0100721)2.60526849
48Inflammation of the large intestine (HP:0002037)2.56479007
49Petechiae (HP:0000967)2.55897128
50Abnormality of B cell number (HP:0010975)2.50400025
51Hemoptysis (HP:0002105)2.49001433
52Hypergammaglobulinemia (HP:0010702)2.47848356
53IgM deficiency (HP:0002850)2.45053388
54Abnormality of cells of the lymphoid lineage (HP:0012140)2.42516809
55Gastrointestinal inflammation (HP:0004386)2.41801377
56Lymphoma (HP:0002665)2.41277815
57Bronchitis (HP:0012387)2.40310722
58Aplastic anemia (HP:0001915)2.39805268
59Obstructive lung disease (HP:0006536)2.37821017
60Chronic obstructive pulmonary disease (HP:0006510)2.37821017
61B lymphocytopenia (HP:0010976)2.33907803
62Pigmentary retinal degeneration (HP:0001146)2.32878755
63Autoimmune thrombocytopenia (HP:0001973)2.27094668
64Abnormality of the pleura (HP:0002103)2.24612221
65Abnormality of the prostate (HP:0008775)2.24516233
66Viral hepatitis (HP:0006562)2.23185538
67Skin rash (HP:0000988)2.20956483
68IgA deficiency (HP:0002720)2.20746355
69Acute hepatic failure (HP:0006554)2.19845290
70Joint swelling (HP:0001386)2.19814139
71Increased IgE level (HP:0003212)2.17655804
72Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.16292739
73Systemic lupus erythematosus (HP:0002725)2.11547024
74Abnormality of liposaccharide metabolism (HP:0010968)2.05410932
75Abnormality of glycosphingolipid metabolism (HP:0004343)2.05410932
76Abnormality of glycolipid metabolism (HP:0010969)2.05410932
77Pulmonary embolism (HP:0002204)2.03830196
78Gangrene (HP:0100758)2.00578293
79Alveolar cell carcinoma (HP:0006519)1.97232477
80Glomerulopathy (HP:0100820)1.95190549
81Purpura (HP:0000979)1.94067082
82Lower limb hyperreflexia (HP:0002395)1.93109330
83Arterial thrombosis (HP:0004420)1.92171883
84Anorexia (HP:0002039)1.91461405
85Abnormality of lateral ventricle (HP:0030047)1.90443188
86Gastrointestinal stroma tumor (HP:0100723)1.85519192
87Neutropenia (HP:0001875)1.84912991
88Chronic otitis media (HP:0000389)1.82599557
89Renal cortical cysts (HP:0000803)1.82450980
90Vertigo (HP:0002321)1.82115045
91Recurrent lower respiratory tract infections (HP:0002783)1.81129680
92Abnormality of the renal cortex (HP:0011035)1.79650009
93Hepatosplenomegaly (HP:0001433)1.78151340
94Basal ganglia calcification (HP:0002135)1.75669650
95Hemorrhage of the eye (HP:0011885)1.74408715
96Neoplasm of the tracheobronchial system (HP:0100552)1.73662230
97Spontaneous hematomas (HP:0007420)1.72545559
98Chest pain (HP:0100749)1.70094398
99Pulmonary fibrosis (HP:0002206)1.68237201
100Polyneuropathy (HP:0001271)1.67251376

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.17182279
2TAOK35.61730167
3MAP4K13.99079226
4FES2.64307873
5EPHA32.58579229
6IRAK42.52074069
7KDR2.28615611
8KIT2.19931919
9BMPR1B2.07109653
10RIPK42.01827648
11GRK62.00269753
12SYK1.86313268
13CSK1.81812419
14ZAP701.80276151
15ITK1.73876412
16EPHB11.73335281
17IKBKE1.65858887
18BCKDK1.63992996
19FGFR41.55807132
20BTK1.55488349
21JAK31.55306588
22JAK11.48299650
23NLK1.45891065
24MAP3K31.41574267
25CDK81.32753023
26LCK1.32350712
27IKBKB1.32303277
28ADRBK21.27033996
29LYN1.22874014
30TLK11.22219729
31MAPKAPK31.21844228
32MAP3K141.21803703
33MAP2K31.21593167
34MUSK1.18640816
35TEC1.16355634
36BLK1.15256339
37MST41.15116206
38HCK1.12590841
39MAPK121.10766864
40TESK21.09629240
41TNK21.07671911
42MARK31.07602210
43TGFBR11.06471595
44PRKCQ1.04551125
45TBK11.00612761
46TRPM70.98866809
47BMPR20.97209625
48GRK70.96138156
49FGFR30.95137834
50NEK60.93877960
51ZAK0.92267490
52PINK10.91761772
53IRAK10.91082717
54TESK10.87006208
55TYK20.84873652
56PIK3CG0.80813947
57GRK10.79487218
58MATK0.76420025
59RPS6KA40.72311943
60MAPK70.68627674
61CSF1R0.68362760
62JAK20.67385847
63HIPK20.66477809
64MAP2K60.65943775
65VRK10.63874985
66PDK10.62590617
67MAPK110.59976205
68CAMKK20.58580358
69PTK2B0.56814282
70MAP4K20.56691340
71FRK0.55639706
72CLK10.55431454
73TGFBR20.53258198
74TYRO30.52750439
75SIK30.52337878
76MAP3K10.50335901
77SCYL20.49959459
78RPS6KA50.48554599
79CDK40.42856335
80MAPKAPK20.41411558
81FYN0.39592793
82STK100.39552337
83DAPK10.39316348
84SGK20.39097655
85IGF1R0.38253954
86GRK50.36649569
87CHUK0.36334338
88ERN10.35716623
89PIM10.32834422
90EIF2AK30.30196512
91PRKCD0.29521013
92PDGFRB0.28744441
93WNK40.28257900
94MAPK130.28249468
95MAP3K130.27564486
96WNK10.27039356
97STK40.27022465
98EGFR0.25519599
99SGK30.25151549
100CDK30.23687672

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.89928161
2Antigen processing and presentation_Homo sapiens_hsa046124.47055113
3Graft-versus-host disease_Homo sapiens_hsa053323.92401686
4Autoimmune thyroid disease_Homo sapiens_hsa053203.54425088
5Allograft rejection_Homo sapiens_hsa053303.53856374
6Intestinal immune network for IgA production_Homo sapiens_hsa046723.10493204
7Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.99555295
8Asthma_Homo sapiens_hsa053102.72140708
9Type I diabetes mellitus_Homo sapiens_hsa049402.65016647
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.56800110
11T cell receptor signaling pathway_Homo sapiens_hsa046602.46721298
12Hematopoietic cell lineage_Homo sapiens_hsa046402.35168186
13NF-kappa B signaling pathway_Homo sapiens_hsa040642.28023199
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.19626382
15Staphylococcus aureus infection_Homo sapiens_hsa051502.00656344
16Measles_Homo sapiens_hsa051621.96910576
17Leishmaniasis_Homo sapiens_hsa051401.89672875
18Viral myocarditis_Homo sapiens_hsa054161.79380108
19Rheumatoid arthritis_Homo sapiens_hsa053231.71035517
20Toll-like receptor signaling pathway_Homo sapiens_hsa046201.66805222
21Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.48824228
22Osteoclast differentiation_Homo sapiens_hsa043801.39820850
23RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.39375800
24Tuberculosis_Homo sapiens_hsa051521.33540260
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.27654653
26Herpes simplex infection_Homo sapiens_hsa051681.27492032
27B cell receptor signaling pathway_Homo sapiens_hsa046621.25031352
28Malaria_Homo sapiens_hsa051441.23881814
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.22200787
30Chemokine signaling pathway_Homo sapiens_hsa040621.21999634
31Jak-STAT signaling pathway_Homo sapiens_hsa046301.21943034
32Systemic lupus erythematosus_Homo sapiens_hsa053221.18286718
33Toxoplasmosis_Homo sapiens_hsa051451.09315194
34Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.00618930
35Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.97037834
36TNF signaling pathway_Homo sapiens_hsa046680.95933679
37Influenza A_Homo sapiens_hsa051640.94839483
38Shigellosis_Homo sapiens_hsa051310.92849198
39Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86228334
40Salmonella infection_Homo sapiens_hsa051320.83626993
41Regulation of autophagy_Homo sapiens_hsa041400.80870244
42Olfactory transduction_Homo sapiens_hsa047400.73236273
43Pertussis_Homo sapiens_hsa051330.73067390
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71799183
45Viral carcinogenesis_Homo sapiens_hsa052030.69723104
46HTLV-I infection_Homo sapiens_hsa051660.68508219
47Platelet activation_Homo sapiens_hsa046110.67206410
48Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67074220
49Phototransduction_Homo sapiens_hsa047440.65457895
50Hepatitis B_Homo sapiens_hsa051610.63723944
51Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.63359184
52Legionellosis_Homo sapiens_hsa051340.63196923
53Apoptosis_Homo sapiens_hsa042100.62297765
54Epstein-Barr virus infection_Homo sapiens_hsa051690.61160451
55Acute myeloid leukemia_Homo sapiens_hsa052210.56824177
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54159957
57Phagosome_Homo sapiens_hsa041450.53541950
58Nitrogen metabolism_Homo sapiens_hsa009100.51931290
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50413743
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49078146
61alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44512280
62Proteasome_Homo sapiens_hsa030500.43816841
63Hepatitis C_Homo sapiens_hsa051600.40462799
64Leukocyte transendothelial migration_Homo sapiens_hsa046700.36712654
65Non-small cell lung cancer_Homo sapiens_hsa052230.35197269
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34616832
67African trypanosomiasis_Homo sapiens_hsa051430.34542701
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.34292849
69Endocytosis_Homo sapiens_hsa041440.32827977
70Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.32387263
71Linoleic acid metabolism_Homo sapiens_hsa005910.30474379
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.26607496
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.26419466
74Renin secretion_Homo sapiens_hsa049240.26393365
75Arachidonic acid metabolism_Homo sapiens_hsa005900.26297363
76Collecting duct acid secretion_Homo sapiens_hsa049660.25924677
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.23116562
78Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.23023227
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.20924618
80Homologous recombination_Homo sapiens_hsa034400.18187201
81MAPK signaling pathway_Homo sapiens_hsa040100.17979627
82Glycosaminoglycan degradation_Homo sapiens_hsa005310.17859150
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.17296341
84Lysosome_Homo sapiens_hsa041420.16912531
85Prolactin signaling pathway_Homo sapiens_hsa049170.16819948
86Alcoholism_Homo sapiens_hsa050340.15282572
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.13681917
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.13102821
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.12939312
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.12680612
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.12366045
92One carbon pool by folate_Homo sapiens_hsa006700.11185404
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.09980559
94Salivary secretion_Homo sapiens_hsa049700.07448513
95Steroid hormone biosynthesis_Homo sapiens_hsa001400.06643571
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.06275323
97Oxidative phosphorylation_Homo sapiens_hsa001900.05872482
98Parkinsons disease_Homo sapiens_hsa050120.05100373
99Oxytocin signaling pathway_Homo sapiens_hsa049210.03961648
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.03774224

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »