TRBJ2-1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine deamination (GO:0009972)9.71631866
2cytidine metabolic process (GO:0046087)9.71631866
3cytidine catabolic process (GO:0006216)9.71631866
4negative thymic T cell selection (GO:0045060)9.09771687
5DNA deamination (GO:0045006)8.81174256
6pyrimidine ribonucleoside catabolic process (GO:0046133)8.65502546
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450918.49997637
8regulation of isotype switching to IgG isotypes (GO:0048302)7.52785176
9positive regulation of gamma-delta T cell activation (GO:0046645)7.45829578
10positive T cell selection (GO:0043368)7.38308164
11thymic T cell selection (GO:0045061)7.24607496
12T cell migration (GO:0072678)7.17292752
13T cell selection (GO:0045058)6.89924337
14eosinophil chemotaxis (GO:0048245)6.83377312
15positive thymic T cell selection (GO:0045059)6.73631463
16negative regulation of cell killing (GO:0031342)6.67974133
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.67974133
18negative regulation by host of viral transcription (GO:0043922)6.49888950
19positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.42938103
20positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.25067788
21eosinophil migration (GO:0072677)6.17693330
22regulation of gamma-delta T cell differentiation (GO:0045586)6.01977151
23interferon-gamma production (GO:0032609)5.76630751
24response to interleukin-15 (GO:0070672)5.75923578
25regulation of T cell tolerance induction (GO:0002664)5.68315825
26T cell receptor signaling pathway (GO:0050852)5.61219750
27positive regulation of alpha-beta T cell proliferation (GO:0046641)5.57947318
28negative regulation of T cell apoptotic process (GO:0070233)5.43275445
29regulation of activation of Janus kinase activity (GO:0010533)5.41983927
30macrophage chemotaxis (GO:0048246)5.38155157
31regulation of gamma-delta T cell activation (GO:0046643)5.35258745
32positive regulation of interleukin-8 secretion (GO:2000484)5.31143040
33cellular response to interleukin-15 (GO:0071350)5.26553039
34regulation of alpha-beta T cell proliferation (GO:0046640)5.23096148
35positive regulation of monocyte chemotaxis (GO:0090026)5.15755396
36antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.12648678
37antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.12648678
38T cell costimulation (GO:0031295)5.06928178
39regulation of lymphocyte chemotaxis (GO:1901623)5.06635566
40regulation of chronic inflammatory response (GO:0002676)5.05569400
41signal complex assembly (GO:0007172)4.96922443
42lymphocyte costimulation (GO:0031294)4.96774905
43mast cell activation (GO:0045576)4.91366870
44positive regulation of isotype switching (GO:0045830)4.90662344
45positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.80511773
46positive regulation of natural killer cell mediated immunity (GO:0002717)4.80511773
47ribosomal small subunit assembly (GO:0000028)4.78972265
48antigen receptor-mediated signaling pathway (GO:0050851)4.74026059
49regulation of natural killer cell mediated immunity (GO:0002715)4.67150304
50regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.67150304
51regulation of T cell chemotaxis (GO:0010819)4.66439963
52positive regulation of T cell chemotaxis (GO:0010820)4.66439963
53monocyte chemotaxis (GO:0002548)4.62173193
54positive regulation of tolerance induction (GO:0002645)4.55770713
55activated T cell proliferation (GO:0050798)4.54993711
56Arp2/3 complex-mediated actin nucleation (GO:0034314)4.51515781
57regulation of interleukin-2 biosynthetic process (GO:0045076)4.41226423
58heterotypic cell-cell adhesion (GO:0034113)4.37375932
59leukocyte aggregation (GO:0070486)4.34700500
60positive regulation of B cell mediated immunity (GO:0002714)4.33164460
61positive regulation of immunoglobulin mediated immune response (GO:0002891)4.33164460
62antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.32636120
63regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.31914621
64positive regulation of lymphocyte migration (GO:2000403)4.28428179
65chaperone-mediated protein transport (GO:0072321)4.25455904
66antigen processing and presentation of endogenous antigen (GO:0019883)4.23096297
67pyrimidine nucleoside catabolic process (GO:0046135)4.17914560
68positive regulation of DNA recombination (GO:0045911)4.17889641
69regulation of mononuclear cell migration (GO:0071675)4.14539588
70regulation of T cell receptor signaling pathway (GO:0050856)4.14357194
71regulation of chemokine-mediated signaling pathway (GO:0070099)4.13241710
72lymphocyte migration (GO:0072676)4.12217523
73positive regulation of T cell apoptotic process (GO:0070234)4.05438880
74megakaryocyte development (GO:0035855)4.04076094
75regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.00086387
76negative regulation of viral genome replication (GO:0045071)3.98499919
77regulation of tolerance induction (GO:0002643)3.95470899
78sequestering of actin monomers (GO:0042989)3.93433599
79regulation of interleukin-8 secretion (GO:2000482)3.92714844
80regulation of interleukin-12 biosynthetic process (GO:0045075)3.91197633
81regulation of B cell receptor signaling pathway (GO:0050855)3.91134001
82positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.90494449
83positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.89596913
84positive regulation of humoral immune response (GO:0002922)3.85774740
85regulation of T cell apoptotic process (GO:0070232)3.85034310
86positive regulation of uterine smooth muscle contraction (GO:0070474)3.84029801
87negative regulation of viral transcription (GO:0032897)3.82020682
88regulation of macrophage chemotaxis (GO:0010758)3.80620522
89regulation of isotype switching (GO:0045191)3.78365056
90T cell differentiation (GO:0030217)3.77883001
91regulation of leukocyte mediated cytotoxicity (GO:0001910)3.77493175
92negative regulation of lymphocyte apoptotic process (GO:0070229)3.75950811
93peroxisome fission (GO:0016559)3.75765419
94SMAD protein complex assembly (GO:0007183)3.73068325
95positive regulation of interleukin-2 production (GO:0032743)3.69619084
96leukocyte cell-cell adhesion (GO:0007159)3.67438814
97positive regulation of translational initiation (GO:0045948)3.64011936
98mast cell activation involved in immune response (GO:0002279)3.60621259
99mast cell degranulation (GO:0043303)3.60621259
100positive regulation of immunoglobulin production (GO:0002639)3.56302463
101negative regulation of T cell mediated immunity (GO:0002710)3.54900444
102regulation of immunoglobulin mediated immune response (GO:0002889)3.54804328
103V(D)J recombination (GO:0033151)3.54505146
104T cell activation (GO:0042110)3.54370267
105regulation of transforming growth factor beta2 production (GO:0032909)3.54232605
106regulation of lymphocyte migration (GO:2000401)3.53258589
107positive regulation of cell killing (GO:0031343)3.49959976
108dendritic cell chemotaxis (GO:0002407)3.48040008
109regulation of T cell mediated cytotoxicity (GO:0001914)3.46948643
110regulation of calcium-mediated signaling (GO:0050848)3.46895460
111modulation by host of symbiont transcription (GO:0052472)3.45642389
112modulation by host of viral transcription (GO:0043921)3.45642389
113regulation of monocyte chemotaxis (GO:0090025)3.43553629
114negative regulation of B cell proliferation (GO:0030889)3.43377114
115protein neddylation (GO:0045116)3.43169328
116regulation of B cell mediated immunity (GO:0002712)3.41895334
117regulation of T cell migration (GO:2000404)3.41535897
118positive regulation of T cell mediated cytotoxicity (GO:0001916)3.40099778
119immune response-activating cell surface receptor signaling pathway (GO:0002429)3.39166136
120regulation of cell killing (GO:0031341)3.38722292
121positive regulation of T cell migration (GO:2000406)3.34600233
122modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)3.32507810
123lymphocyte chemotaxis (GO:0048247)3.25632751
124regulation of response to tumor cell (GO:0002834)3.24598909
125positive regulation of response to tumor cell (GO:0002836)3.24598909
126positive regulation of immune response to tumor cell (GO:0002839)3.24598909
127regulation of immune response to tumor cell (GO:0002837)3.24598909
128actin nucleation (GO:0045010)3.22641257
129B cell receptor signaling pathway (GO:0050853)3.22519644
130positive regulation of calcium-mediated signaling (GO:0050850)3.19663394
131alpha-beta T cell activation (GO:0046631)3.18618185
132cellular defense response (GO:0006968)3.17131896
133alpha-beta T cell differentiation (GO:0046632)3.16434305
134T cell proliferation (GO:0042098)3.14949724
135positive regulation of gluconeogenesis (GO:0045722)3.14380969
136cytolysis (GO:0019835)3.13687230
137granulocyte activation (GO:0036230)3.13173387
138microtubule severing (GO:0051013)3.12915764
139negative regulation of stress fiber assembly (GO:0051497)3.12405659
140positive regulation of defense response to virus by host (GO:0002230)3.11626599
141regulation of regulatory T cell differentiation (GO:0045589)3.11462634
142positive regulation of lymphocyte apoptotic process (GO:0070230)3.11393115
143positive regulation of lymphocyte mediated immunity (GO:0002708)3.10642360
144regulation of defense response to virus by virus (GO:0050690)3.08877517
145cellular response to interleukin-4 (GO:0071353)3.07557158
146T cell homeostasis (GO:0043029)3.05867806
147negative regulation of T cell receptor signaling pathway (GO:0050860)3.03638143
148leukocyte tethering or rolling (GO:0050901)3.02046506
149RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.99987107
150tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.99987107
151regulation of lymphocyte apoptotic process (GO:0070228)2.99783225
152negative regulation of B cell activation (GO:0050869)2.99401468
153regulation of immunoglobulin production (GO:0002637)2.99165088
154iron-sulfur cluster assembly (GO:0016226)2.98336521
155metallo-sulfur cluster assembly (GO:0031163)2.98336521
156positive regulation of macrophage differentiation (GO:0045651)2.97408208
157lymph node development (GO:0048535)2.96882114
158regulation of uterine smooth muscle contraction (GO:0070472)2.95831539
159poly(A)+ mRNA export from nucleus (GO:0016973)2.95413893
160regulation of B cell differentiation (GO:0045577)2.94214227
161negative T cell selection (GO:0043383)10.1069593

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.56603974
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.21440977
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.87053780
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.87176702
5RUNX_20019798_ChIP-Seq_JUKART_Human3.66482379
6MYC_22102868_ChIP-Seq_BL_Human3.62777997
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.59181888
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.54633105
9IRF8_22096565_ChIP-ChIP_GC-B_Human3.43418572
10IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.37111186
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.25396643
12FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.24534239
13STAT4_19710469_ChIP-ChIP_TH1__Mouse3.22301587
14MYB_26560356_Chip-Seq_TH2_Human3.09090913
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.69636824
16MAF_26560356_Chip-Seq_TH1_Human2.67160682
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.55340629
18UTX_26944678_Chip-Seq_JUKART_Human2.53973648
19STAT6_21828071_ChIP-Seq_BEAS2B_Human2.48630069
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.44614513
21MYB_26560356_Chip-Seq_TH1_Human2.38760727
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.28428512
23GATA3_27048872_Chip-Seq_THYMUS_Human2.22280766
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18417642
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.12831278
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.04780184
27VDR_22108803_ChIP-Seq_LS180_Human1.92085477
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.90612105
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87803483
30IRF8_21731497_ChIP-ChIP_J774_Mouse1.81586160
31HTT_18923047_ChIP-ChIP_STHdh_Human1.78922434
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.78331785
33KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.78119166
34SPI1_23547873_ChIP-Seq_NB4_Human1.76019555
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.73244939
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.70693453
37MAF_26560356_Chip-Seq_TH2_Human1.69616075
38E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.63706444
39SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.60853456
40FOXM1_23109430_ChIP-Seq_U2OS_Human1.59852999
41VDR_24763502_ChIP-Seq_THP-1_Human1.58885344
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57359251
43E2F4_17652178_ChIP-ChIP_JURKAT_Human1.56607982
44VDR_21846776_ChIP-Seq_THP-1_Human1.54001951
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52035434
46RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.52003327
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.51609398
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.50572595
49MYB_21317192_ChIP-Seq_ERMYB_Mouse1.50016029
50KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.49886237
51NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.49465141
52NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.46834230
53CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.45938946
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.44250364
55TCF7_22412390_ChIP-Seq_EML_Mouse1.43492947
56JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.40172912
57TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.35323817
58MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.34353245
59KDM2B_26808549_Chip-Seq_DND41_Human1.34099693
60SCL_19346495_ChIP-Seq_HPC-7_Human1.32834146
61RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.27056033
62ELF1_20517297_ChIP-Seq_JURKAT_Human1.26517123
63FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.23387238
64TAF2_19829295_ChIP-Seq_ESCs_Human1.22323533
65HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17073647
66NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.16446651
67IRF8_27001747_Chip-Seq_BMDM_Mouse1.15727131
68PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14954276
69VDR_23849224_ChIP-Seq_CD4+_Human1.14251665
70ELK1_19687146_ChIP-ChIP_HELA_Human1.13219836
71TP53_22573176_ChIP-Seq_HFKS_Human1.12054766
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10779024
73GATA3_26560356_Chip-Seq_TH2_Human1.09805421
74CIITA_25753668_ChIP-Seq_RAJI_Human1.08869084
75SPI1_23127762_ChIP-Seq_K562_Human1.07695239
76CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06852947
77EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05848329
78GATA1_22025678_ChIP-Seq_K562_Human1.05820321
79VDR_24787735_ChIP-Seq_THP-1_Human1.05625735
80MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.03547457
81IGF1R_20145208_ChIP-Seq_DFB_Human1.03009058
82PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.03000870
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.01473047
84BCL6_27268052_Chip-Seq_Bcells_Human1.00273108
85FOXP3_21729870_ChIP-Seq_TREG_Human0.98677978
86NANOG_20526341_ChIP-Seq_ESCs_Human0.98637253
87P300_27268052_Chip-Seq_Bcells_Human0.98020713
88EST1_17652178_ChIP-ChIP_JURKAT_Human0.97611927
89CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97451877
90LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96599520
91NANOG_19829295_ChIP-Seq_ESCs_Human0.95182329
92SOX2_19829295_ChIP-Seq_ESCs_Human0.95182329
93PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.93564002
94KDM2B_26808549_Chip-Seq_SUP-B15_Human0.93301370
95FOXH1_21741376_ChIP-Seq_EPCs_Human0.93293796
96BRD4_27068464_Chip-Seq_AML-cells_Mouse0.93197382
97TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.91956522
98PCGF2_27294783_Chip-Seq_NPCs_Mouse0.91813928
99LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.91061026
100SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90635391
101GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90413975
102ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89491977
103GATA2_22383799_ChIP-Seq_G1ME_Mouse0.89344104
104PU_27001747_Chip-Seq_BMDM_Mouse0.89065291
105FLI1_27457419_Chip-Seq_LIVER_Mouse0.88377257
106GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.88326985
107CTCF_20526341_ChIP-Seq_ESCs_Human0.88003174
108GATA1_19941826_ChIP-Seq_K562_Human0.87936406
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87604444
110GATA3_21878914_ChIP-Seq_MCF-7_Human0.87484166
111GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86660697
112EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.85847006
113BP1_19119308_ChIP-ChIP_Hs578T_Human0.84973599
114PU.1_20513432_ChIP-Seq_Bcells_Mouse0.84398278
115TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.83014214
116GATA6_21074721_ChIP-Seq_CACO-2_Human0.83013145
117HOXB4_20404135_ChIP-ChIP_EML_Mouse0.82177470
118RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81416221
119SA1_27219007_Chip-Seq_Bcells_Human0.81137878
120FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80827600
121ERG_20517297_ChIP-Seq_VCAP_Human0.80683636
122YY1_21170310_ChIP-Seq_MESCs_Mouse0.80459565
123NOTCH1_21737748_ChIP-Seq_TLL_Human0.80273056
124GABP_17652178_ChIP-ChIP_JURKAT_Human0.79561694
125SRF_21415370_ChIP-Seq_HL-1_Mouse0.79560668
126ETS1_20019798_ChIP-Seq_JURKAT_Human0.79372933
127MYC_18940864_ChIP-ChIP_HL60_Human0.79285567
128MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.79269478
129RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.78995180
130PCGF2_27294783_Chip-Seq_ESCs_Mouse0.78689219
131CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78400905
132POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.77737993
133NCOR_22424771_ChIP-Seq_293T_Human0.77238919
134EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.76735990
135ERA_21632823_ChIP-Seq_H3396_Human0.76579020
136CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75733145
137YY1_22570637_ChIP-Seq_MALME-3M_Human0.75299123
138FOXA1_21572438_ChIP-Seq_LNCaP_Human0.74599533
139RBPJ_21746931_ChIP-Seq_IB4_Human0.74081602
140RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.73683397
141P53_21459846_ChIP-Seq_SAOS-2_Human0.73629342
142E2F1_21310950_ChIP-Seq_MCF-7_Human0.73541876
143SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.73386700
144FLI1_21867929_ChIP-Seq_CD8_Mouse0.72925051
145BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.72570849
146NCOR1_26117541_ChIP-Seq_K562_Human0.71478965
147PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.70079040
148P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.69694868
149CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.69288293
150NFE2_27457419_Chip-Seq_LIVER_Mouse0.69276455
151GATA3_26560356_Chip-Seq_TH1_Human0.68800001
152KDM2B_26808549_Chip-Seq_JURKAT_Human0.68343807
153ETS1_21867929_ChIP-Seq_TH2_Mouse0.67470133
154GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.67251104
155GATA1_22383799_ChIP-Seq_G1ME_Mouse0.66878431
156PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.66777259

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.51700303
2MP0005671_abnormal_response_to5.54659186
3MP0006054_spinal_hemorrhage4.06548750
4MP0000685_abnormal_immune_system3.59455622
5MP0009333_abnormal_splenocyte_physiolog3.20940048
6MP0002166_altered_tumor_susceptibility3.05169124
7MP0001873_stomach_inflammation3.01722631
8MP0000703_abnormal_thymus_morphology2.87895344
9MP0002398_abnormal_bone_marrow2.85365013
10MP0001835_abnormal_antigen_presentation2.81244991
11MP0001800_abnormal_humoral_immune2.80900924
12MP0002420_abnormal_adaptive_immunity2.70661336
13MP0005000_abnormal_immune_tolerance2.65901027
14MP0001819_abnormal_immune_cell2.65029591
15MP0009785_altered_susceptibility_to2.58982980
16MP0010352_gastrointestinal_tract_polyps2.52303267
17MP0002723_abnormal_immune_serum2.42265320
18MP0002006_tumorigenesis2.37234161
19MP0002722_abnormal_immune_system2.36668041
20MP0005025_abnormal_response_to2.35714886
21MP0000716_abnormal_immune_system2.34365041
22MP0002405_respiratory_system_inflammati2.30154280
23MP0002452_abnormal_antigen_presenting2.23137755
24MP0002933_joint_inflammation2.20329572
25MP0000689_abnormal_spleen_morphology2.20176672
26MP0000372_irregular_coat_pigmentation2.15454591
27MP0006082_CNS_inflammation2.09647686
28MP0001790_abnormal_immune_system2.06895258
29MP0005387_immune_system_phenotype2.06895258
30MP0003300_gastrointestinal_ulcer2.05439495
31MP0000858_altered_metastatic_potential1.97860889
32MP0005623_abnormal_meninges_morphology1.95220449
33MP0002429_abnormal_blood_cell1.88681217
34MP0002396_abnormal_hematopoietic_system1.80218528
35MP0004947_skin_inflammation1.74902289
36MP0005464_abnormal_platelet_physiology1.72876124
37MP0002419_abnormal_innate_immunity1.72186980
38MP0002148_abnormal_hypersensitivity_rea1.71351569
39MP0004145_abnormal_muscle_electrophysio1.63874682
40MP0001845_abnormal_inflammatory_respons1.62265024
41MP0010155_abnormal_intestine_physiology1.61549055
42MP0005360_urolithiasis1.50564641
43MP0003448_altered_tumor_morphology1.50076941
44MP0003436_decreased_susceptibility_to1.50064833
45MP0003866_abnormal_defecation1.48989913
46MP0001529_abnormal_vocalization1.48283971
47MP0004957_abnormal_blastocyst_morpholog1.40480485
48MP0004147_increased_porphyrin_level1.38204807
49MP0001661_extended_life_span1.38107803
50MP0005083_abnormal_biliary_tract1.32876961
51MP0003724_increased_susceptibility_to1.32713063
52MP0004381_abnormal_hair_follicle1.32029927
53MP0003646_muscle_fatigue1.29208777
54MP0005646_abnormal_pituitary_gland1.29169682
55MP0003045_fibrosis1.27127286
56MP0003075_altered_response_to1.26807558
57MP0003786_premature_aging1.26688805
58MP0002019_abnormal_tumor_incidence1.22172436
59MP0005645_abnormal_hypothalamus_physiol1.21813646
60MP0010307_abnormal_tumor_latency1.20969589
61MP0005377_hearing/vestibular/ear_phenot1.19233343
62MP0003878_abnormal_ear_physiology1.19233343
63MP0002163_abnormal_gland_morphology1.18700869
64MP0004808_abnormal_hematopoietic_stem1.18415917
65MP0000569_abnormal_digit_pigmentation1.16298360
66MP0002234_abnormal_pharynx_morphology1.13401487
67MP0002277_abnormal_respiratory_mucosa1.13288121
68MP0001188_hyperpigmentation1.03246375
69MP0003705_abnormal_hypodermis_morpholog1.00257842
70MP0000465_gastrointestinal_hemorrhage0.97682164
71MP0003137_abnormal_impulse_conducting0.97039320
72MP0002693_abnormal_pancreas_physiology0.96643455
73MP0005310_abnormal_salivary_gland0.96509920
74MP0003806_abnormal_nucleotide_metabolis0.96484510
75MP0010094_abnormal_chromosome_stability0.96187410
76MP0003880_abnormal_central_pattern0.94823700
77MP0001905_abnormal_dopamine_level0.94731538
78MP0001984_abnormal_olfaction0.94451308
79MP0009764_decreased_sensitivity_to0.93639231
80MP0008469_abnormal_protein_level0.92614162
81MP0002876_abnormal_thyroid_physiology0.91931808
82MP0003279_aneurysm0.90040468
83MP0001853_heart_inflammation0.89924293
84MP0008057_abnormal_DNA_replication0.89698383
85MP0005174_abnormal_tail_pigmentation0.89015345
86MP0005023_abnormal_wound_healing0.88626001
87MP0005410_abnormal_fertilization0.86813229
88MP0003693_abnormal_embryo_hatching0.86489733
89MP0003077_abnormal_cell_cycle0.85846896
90MP0005397_hematopoietic_system_phenotyp0.83201224
91MP0001545_abnormal_hematopoietic_system0.83201224
92MP0002009_preneoplasia0.82993940
93MP0003453_abnormal_keratinocyte_physiol0.81715231
94MP0002102_abnormal_ear_morphology0.81220843
95MP0001968_abnormal_touch/_nociception0.80351229
96MP0000920_abnormal_myelination0.79517319
97MP0003890_abnormal_embryonic-extraembry0.79108455
98MP0001851_eye_inflammation0.76691017
99MP0001765_abnormal_ion_homeostasis0.76420614
100MP0005166_decreased_susceptibility_to0.76343243
101MP0005075_abnormal_melanosome_morpholog0.76281236
102MP0003303_peritoneal_inflammation0.75536077
103MP0005636_abnormal_mineral_homeostasis0.74003682
104MP0003567_abnormal_fetal_cardiomyocyte0.73452476
105MP0008872_abnormal_physiological_respon0.72595271
106MP0005408_hypopigmentation0.72565692
107MP0002138_abnormal_hepatobiliary_system0.72099439
108MP0000639_abnormal_adrenal_gland0.71705716
109MP0003252_abnormal_bile_duct0.70997510
110MP0009643_abnormal_urine_homeostasis0.69703741
111MP0001919_abnormal_reproductive_system0.69604348
112MP0005551_abnormal_eye_electrophysiolog0.69272257
113MP0001533_abnormal_skeleton_physiology0.68474321
114MP0000490_abnormal_crypts_of0.65966428
115MP0009763_increased_sensitivity_to0.64714997
116MP0008873_increased_physiological_sensi0.64678525
117MP0002638_abnormal_pupillary_reflex0.62802621
118MP0002132_abnormal_respiratory_system0.61583110
119MP0002736_abnormal_nociception_after0.61488103
120MP0001191_abnormal_skin_condition0.60376859
121MP0008770_decreased_survivor_rate0.58766821
122MP0005379_endocrine/exocrine_gland_phen0.57815988
123MP0008058_abnormal_DNA_repair0.56805057
124MP0004510_myositis0.56285675
125MP0008875_abnormal_xenobiotic_pharmacok0.55888478
126MP0002998_abnormal_bone_remodeling0.55470193
127MP0002733_abnormal_thermal_nociception0.54738426
128MP0001542_abnormal_bone_strength0.54286735
129MP0010234_abnormal_vibrissa_follicle0.54280829
130MP0001243_abnormal_dermal_layer0.54048887
131MP0009379_abnormal_foot_pigmentation0.53726645
132MP0001663_abnormal_digestive_system0.52457759
133MP0003795_abnormal_bone_structure0.50489923
134MP0000609_abnormal_liver_physiology0.48870078
135MP0001764_abnormal_homeostasis0.46881427
136MP0005584_abnormal_enzyme/coenzyme_acti0.46696321
137MP0000350_abnormal_cell_proliferation0.46612319
138MP0000477_abnormal_intestine_morphology0.46109267
139MP0008877_abnormal_DNA_methylation0.45719740
140MP0002822_catalepsy0.45418574
141MP0001730_embryonic_growth_arrest0.45128146
142MP0003091_abnormal_cell_migration0.44565152
143MP0002083_premature_death0.44433192
144MP0002136_abnormal_kidney_physiology0.43712169
145MP0009765_abnormal_xenobiotic_induced0.43488201
146MP0000249_abnormal_blood_vessel0.43142060
147MP0005332_abnormal_amino_acid0.42580615

Predicted human phenotypes

RankGene SetZ-score
1Myositis (HP:0100614)7.98823103
2T lymphocytopenia (HP:0005403)7.28519149
3Abnormality of T cell number (HP:0011839)6.95608210
4Retrobulbar optic neuritis (HP:0100654)5.48292980
5Optic neuritis (HP:0100653)5.48292980
6Keratoconjunctivitis sicca (HP:0001097)5.41748859
7Keratoconjunctivitis (HP:0001096)4.88648616
8Orchitis (HP:0100796)4.88197192
9Aplastic anemia (HP:0001915)4.81990441
10Elevated erythrocyte sedimentation rate (HP:0003565)4.56513142
11Encephalitis (HP:0002383)4.47364583
12Chronic diarrhea (HP:0002028)4.37978038
13Increased IgM level (HP:0003496)4.33110727
14Severe combined immunodeficiency (HP:0004430)4.18616263
15Pustule (HP:0200039)4.12086922
16Combined immunodeficiency (HP:0005387)4.09149642
17Abnormality of T cells (HP:0002843)3.95666330
18Recurrent abscess formation (HP:0002722)3.83904157
19Chronic otitis media (HP:0000389)3.81734629
20Joint swelling (HP:0001386)3.78971329
21Abnormality of the prostate (HP:0008775)3.59847639
22Spontaneous hematomas (HP:0007420)3.54001212
23IgG deficiency (HP:0004315)3.53750257
24Abnormal delayed hypersensitivity skin test (HP:0002963)3.52506277
25Chronic obstructive pulmonary disease (HP:0006510)3.49711996
26Obstructive lung disease (HP:0006536)3.49711996
27Recurrent viral infections (HP:0004429)3.47117083
28Eosinophilia (HP:0001880)3.40980054
29Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.28186021
30Decreased activity of mitochondrial respiratory chain (HP:0008972)3.28186021
31Recurrent bacterial skin infections (HP:0005406)3.25024203
323-Methylglutaconic aciduria (HP:0003535)3.24591601
33Abnormal platelet volume (HP:0011876)3.21817567
34Ureteral stenosis (HP:0000071)3.17989909
35Abnormality of eosinophils (HP:0001879)3.13517142
36Birth length less than 3rd percentile (HP:0003561)3.12271351
37Pulmonary embolism (HP:0002204)3.11381441
3811 pairs of ribs (HP:0000878)3.06850065
39Colon cancer (HP:0003003)3.05306501
40Arterial thrombosis (HP:0004420)3.05111243
41Thyroiditis (HP:0100646)3.04392032
42Spondylolisthesis (HP:0003302)3.02174994
43Increased mean platelet volume (HP:0011877)3.01662532
44Chronic mucocutaneous candidiasis (HP:0002728)3.00535947
45Recurrent cutaneous fungal infections (HP:0011370)3.00535947
46Abnormal albumin level (HP:0012116)3.00048641
47Hypoalbuminemia (HP:0003073)3.00048641
48Nasal polyposis (HP:0100582)2.99089473
49Abnormality of macrophages (HP:0004311)2.94267048
50Panhypogammaglobulinemia (HP:0003139)2.92423401
51Meningitis (HP:0001287)2.91924960
52Ureteral obstruction (HP:0006000)2.90146691
53Leukocytosis (HP:0001974)2.89469203
54Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.88173008
55Mitochondrial inheritance (HP:0001427)2.86658556
56Thrombocytosis (HP:0001894)2.80596766
57Agammaglobulinemia (HP:0004432)2.79256385
58Hemoptysis (HP:0002105)2.78311831
59Stomatitis (HP:0010280)2.77809659
60Absent rod-and cone-mediated responses on ERG (HP:0007688)2.77216175
61Autoimmune thrombocytopenia (HP:0001973)2.75891751
62Increased intramyocellular lipid droplets (HP:0012240)2.75863234
63Granulocytopenia (HP:0001913)2.75709357
64B lymphocytopenia (HP:0010976)2.75441860
65Abnormality of B cell number (HP:0010975)2.75441860
66Acute necrotizing encephalopathy (HP:0006965)2.73060039
67Arterial tortuosity (HP:0005116)2.67326575
68Autoimmune hemolytic anemia (HP:0001890)2.62303913
69Abnormality of T cell physiology (HP:0011840)2.61618200
70Pancreatic islet-cell hyperplasia (HP:0004510)2.57895203
71Long clavicles (HP:0000890)2.57280906
72Abnormal mitochondria in muscle tissue (HP:0008316)2.56599297
73Chest pain (HP:0100749)2.55574359
74Hemiplegia (HP:0002301)2.53966859
75Recurrent bronchitis (HP:0002837)2.50415943
76Hypoplasia of the thymus (HP:0000778)2.48385933
77Dry hair (HP:0011359)2.47163019
78Recurrent fungal infections (HP:0002841)2.46531895
79Eczematoid dermatitis (HP:0000976)2.43631880
80Abnormality of the nasal mucosa (HP:0000433)2.43101791
81Bronchitis (HP:0012387)2.41364832
82Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.41172761
83Short 4th metacarpal (HP:0010044)2.41172761
84Hypergammaglobulinemia (HP:0010702)2.39909401
85Lymphopenia (HP:0001888)2.36996917
86Nonimmune hydrops fetalis (HP:0001790)2.36851966
87Hematochezia (HP:0002573)2.36648662
88Abnormality of the pleura (HP:0002103)2.33466285
89Gangrene (HP:0100758)2.32202729
90Vascular tortuosity (HP:0004948)2.29902370
91Petechiae (HP:0000967)2.29810719
92J-shaped sella turcica (HP:0002680)2.29453040
93Severe visual impairment (HP:0001141)2.28786187
94Pulmonary infiltrates (HP:0002113)2.28061035
95Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.27086093
96Abnormality of cells of the lymphoid lineage (HP:0012140)2.25880190
97Keratitis (HP:0000491)2.24930540
98Progressive macrocephaly (HP:0004481)2.23210281
99Striae distensae (HP:0001065)2.23128427
100Delayed closure of the anterior fontanelle (HP:0001476)2.22646923
101Recurrent gram-negative bacterial infections (HP:0005420)2.22067729
102Generalized aminoaciduria (HP:0002909)2.21720417
103Microcytic anemia (HP:0001935)2.20565242
104Aortic aneurysm (HP:0004942)2.19111986
105Neoplasm of the small intestine (HP:0100833)2.17942285
106Biliary tract neoplasm (HP:0100574)2.17361493
107Acute hepatic failure (HP:0006554)2.15992366
108Aseptic necrosis (HP:0010885)2.15624940
109Acute encephalopathy (HP:0006846)2.14905371
110IgM deficiency (HP:0002850)2.14547548
111Increased muscle lipid content (HP:0009058)2.14062933
112Cerebral palsy (HP:0100021)2.14000776
113Lymphoma (HP:0002665)2.13845205
114Aortic dissection (HP:0002647)2.13841184
115Epistaxis (HP:0000421)2.11592266
116Renal cortical cysts (HP:0000803)2.10387386
117Hepatocellular necrosis (HP:0001404)2.08616947
118Recurrent otitis media (HP:0000403)2.07626924
119Pulmonary fibrosis (HP:0002206)2.07089319
120Congenital stationary night blindness (HP:0007642)2.06727964
121Increased serum ferritin (HP:0003281)2.05307763
122Cerebral edema (HP:0002181)2.04995776
123Vasculitis (HP:0002633)2.03996064
124Pancreatic fibrosis (HP:0100732)2.03756031
125Amyotrophic lateral sclerosis (HP:0007354)2.03467262
126Toxemia of pregnancy (HP:0100603)2.02385485
127Hypoproteinemia (HP:0003075)2.01299753
128Recurrent skin infections (HP:0001581)2.00353196
129Recurrent sinusitis (HP:0011108)1.99573689
130Increased CSF lactate (HP:0002490)1.98107430
131Radial bowing (HP:0002986)1.97784517
132Pancytopenia (HP:0001876)1.97757896
133Mesomelia (HP:0003027)1.97454611
134Menstrual irregularities (HP:0000858)1.96616319
135Gastrointestinal infarctions (HP:0005244)1.95792354
136Chronic sinusitis (HP:0011109)1.94901073
137Broad face (HP:0000283)1.94167027
138Prolonged bleeding time (HP:0003010)1.93696153
139Glomerulopathy (HP:0100820)1.93663125
140Thrombophlebitis (HP:0004418)1.93415512
141Abnormality of male internal genitalia (HP:0000022)1.92145682
142Renal Fanconi syndrome (HP:0001994)1.91937556
143Tetraplegia (HP:0002445)1.91715682
144Abnormal hair whorl (HP:0010721)1.91364048
145Periorbital edema (HP:0100539)1.90230570
146Rectal prolapse (HP:0002035)1.89401862
147IgA deficiency (HP:0002720)1.89215276
148Abnormality of the pericardium (HP:0001697)1.89209463
149Cellular immunodeficiency (HP:0005374)1.88480549
150True hermaphroditism (HP:0010459)1.87945219
151Facial edema (HP:0000282)1.86081905
152Protrusio acetabuli (HP:0003179)1.85570335
153Pancreatic cysts (HP:0001737)1.84094760
154Increased hepatocellular lipid droplets (HP:0006565)1.82803612
155Abnormal rod and cone electroretinograms (HP:0008323)1.76715790
156Hepatic necrosis (HP:0002605)1.76208944
157Pancreatitis (HP:0001733)1.76168398

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK5.93629170
2MAP4K14.61933892
3CDK84.53529088
4ITK3.33716627
5ZAK3.25861575
6NLK3.24522496
7CLK13.24403365
8MELK3.04188606
9MAP2K62.98838794
10ZAP702.96528253
11MST42.83367534
12BCKDK2.69384997
13NME22.56479518
14MAP3K142.49180362
15ACVR1B2.31708901
16VRK22.29449895
17PRPF4B2.25367542
18STK102.12719422
19JAK32.03546079
20SCYL21.91651379
21GRK61.90601158
22TESK11.87743984
23LCK1.85429895
24GRK71.83119084
25VRK11.78205788
26PRKCH1.74179881
27BLK1.68673924
28LIMK11.68490823
29MAP3K71.67443223
30ADRBK21.64557234
31CDK91.63403529
32BUB11.59089277
33SYK1.53749007
34CSK1.46732357
35SIK31.45581099
36EPHA31.38225668
37FGFR41.33229993
38MAP3K121.29571732
39CDK41.28859982
40TYK21.24236000
41MAP3K111.21534938
42BRSK11.17390123
43DAPK11.11299456
44TAOK31.11223968
45MAPKAPK31.10033798
46BRSK21.08004197
47HCK1.05121388
48KDR1.04294727
49GRK11.01385888
50MYLK1.00481582
51LRRK20.98842972
52IKBKE0.98319992
53BTK0.96499651
54TESK20.95277118
55WEE10.95083198
56JAK10.92326808
57FGFR30.91371147
58TEC0.90926216
59PKN20.90100631
60MAP4K20.88787413
61MARK30.87960834
62TBK10.86987603
63CDK190.83396004
64MATK0.81363794
65PIM10.80908148
66TIE10.80703525
67CDC70.80695911
68TRIM280.78325096
69PIK3CA0.78225974
70PRKCQ0.74579132
71NUAK10.72710050
72WNK40.71874752
73FES0.69069003
74EEF2K0.68676093
75KSR10.68365760
76TRPM70.67316906
77LYN0.66304054
78PIK3CG0.64664707
79SIK20.54531395
80FGFR20.53794450
81ROCK10.53316681
82FRK0.53127088
83EIF2AK30.52112851
84AURKA0.49871534
85PRKG20.48872128
86NEK90.47705264
87INSRR0.46494913
88TSSK60.46480178
89TYRO30.45955891
90BCR0.45874371
91CSNK1G30.44550640
92MAP3K50.44410963
93RAF10.44195185
94PDGFRB0.43273377
95NTRK10.42989291
96PAK40.42783535
97OBSCN0.42420848
98FYN0.41802241
99DAPK20.41744642
100SIK10.41193110
101RPS6KC10.41099892
102RPS6KL10.41099892
103CSF1R0.40971047
104CSNK1A1L0.39922021
105RPS6KA50.39362899
106JAK20.38264781
107RPS6KA60.37895548
108TLK10.37501116
109PRKCA0.36778365
110PASK0.35290811
111MAP3K130.34084073
112MAP3K100.32958355
113CSNK1A10.32826624
114TNK20.32686410
115SGK30.32605125
116CAMK2A0.31682177
117IGF1R0.31134644
118KSR20.30324350
119PINK10.30298253
120KIT0.29777706
121INSR0.28933361
122MAPK110.28748775
123ALK0.28619375
124PAK10.28412336
125OXSR10.28305568
126DAPK30.27262604
127RIPK40.26817696
128ERBB20.26578782
129EPHB10.26570445
130MUSK0.25355897
131STK110.25014852
132PRKCD0.24058402
133RPS6KB20.23987134
134ADRBK10.23536448
135SRC0.23053842
136MARK20.22652287
137RPS6KA40.22207302
138FGFR10.21972500
139TRIB30.21006730
140ATR0.19740770
141PRKACA0.19498633
142STK40.19431289
143CDK60.18939698
144PAK30.18673986
145CSNK1G20.18422534
146PDK10.17793191
147CSNK1G10.17075388
148CSNK2A10.16937756
149IKBKB0.16328345
150MAPK70.15158994
151MAP2K20.14758685
152CDK180.14712487
153ABL10.14565666
154MAPK30.14565419
155HIPK20.13533917
156ILK0.12886501

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053326.28441808
2Primary immunodeficiency_Homo sapiens_hsa053405.25636220
3Antigen processing and presentation_Homo sapiens_hsa046124.19643069
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046504.12209308
5T cell receptor signaling pathway_Homo sapiens_hsa046604.02698779
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.82524711
7Hematopoietic cell lineage_Homo sapiens_hsa046402.75112426
8Allograft rejection_Homo sapiens_hsa053302.74692956
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.54289301
10Oxidative phosphorylation_Homo sapiens_hsa001902.48845806
11Measles_Homo sapiens_hsa051622.40165845
12Parkinsons disease_Homo sapiens_hsa050122.11104112
13Viral myocarditis_Homo sapiens_hsa054162.04788090
14Type I diabetes mellitus_Homo sapiens_hsa049401.96991119
15Autoimmune thyroid disease_Homo sapiens_hsa053201.74247911
16Ribosome_Homo sapiens_hsa030101.68234828
17Leukocyte transendothelial migration_Homo sapiens_hsa046701.62992439
18Non-homologous end-joining_Homo sapiens_hsa034501.61781588
19Leishmaniasis_Homo sapiens_hsa051401.59348158
20Colorectal cancer_Homo sapiens_hsa052101.57527340
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.56813327
22Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.46946863
23Alzheimers disease_Homo sapiens_hsa050101.40498078
24DNA replication_Homo sapiens_hsa030301.38216738
25Proteasome_Homo sapiens_hsa030501.37985035
26Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.25843867
27Nucleotide excision repair_Homo sapiens_hsa034201.24625454
28Hepatitis B_Homo sapiens_hsa051611.24247731
29NF-kappa B signaling pathway_Homo sapiens_hsa040641.23904195
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.23523071
31Toll-like receptor signaling pathway_Homo sapiens_hsa046201.20004683
32Mismatch repair_Homo sapiens_hsa034301.19041200
33Asthma_Homo sapiens_hsa053101.14958800
34Chemokine signaling pathway_Homo sapiens_hsa040621.07855734
35Spliceosome_Homo sapiens_hsa030401.04322671
36Phototransduction_Homo sapiens_hsa047441.04231694
37Jak-STAT signaling pathway_Homo sapiens_hsa046301.02947082
38Huntingtons disease_Homo sapiens_hsa050161.02748705
39Cardiac muscle contraction_Homo sapiens_hsa042601.00694783
40Herpes simplex infection_Homo sapiens_hsa051680.98692061
41Staphylococcus aureus infection_Homo sapiens_hsa051500.97779369
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.96650589
43Pancreatic cancer_Homo sapiens_hsa052120.96028665
44HTLV-I infection_Homo sapiens_hsa051660.94849428
45Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92350152
46Nitrogen metabolism_Homo sapiens_hsa009100.90788061
47Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.85469100
48Caffeine metabolism_Homo sapiens_hsa002320.84671380
49NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84236567
50RNA polymerase_Homo sapiens_hsa030200.81554112
51Osteoclast differentiation_Homo sapiens_hsa043800.81303102
52Protein export_Homo sapiens_hsa030600.78744515
53Prion diseases_Homo sapiens_hsa050200.77396107
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76227739
55Systemic lupus erythematosus_Homo sapiens_hsa053220.75590431
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.73126722
57Cell cycle_Homo sapiens_hsa041100.72164542
58Platelet activation_Homo sapiens_hsa046110.69334627
59B cell receptor signaling pathway_Homo sapiens_hsa046620.69316388
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66967786
61Influenza A_Homo sapiens_hsa051640.66904696
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64116890
63Viral carcinogenesis_Homo sapiens_hsa052030.63947445
64Shigellosis_Homo sapiens_hsa051310.63202543
65Adherens junction_Homo sapiens_hsa045200.62078908
66Chronic myeloid leukemia_Homo sapiens_hsa052200.61565201
67Pyrimidine metabolism_Homo sapiens_hsa002400.61047155
68Retinol metabolism_Homo sapiens_hsa008300.59912780
69Acute myeloid leukemia_Homo sapiens_hsa052210.54903491
70One carbon pool by folate_Homo sapiens_hsa006700.54419340
71Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.53255497
72Steroid hormone biosynthesis_Homo sapiens_hsa001400.52720997
73Pertussis_Homo sapiens_hsa051330.51939785
74Linoleic acid metabolism_Homo sapiens_hsa005910.51718783
75Legionellosis_Homo sapiens_hsa051340.49486526
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49257236
77Epstein-Barr virus infection_Homo sapiens_hsa051690.49101106
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48644280
79Rheumatoid arthritis_Homo sapiens_hsa053230.48634519
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48329715
81Apoptosis_Homo sapiens_hsa042100.46908685
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46114523
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.45313345
84Salmonella infection_Homo sapiens_hsa051320.44429692
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.43600148
86Collecting duct acid secretion_Homo sapiens_hsa049660.43057875
87Basal transcription factors_Homo sapiens_hsa030220.42097776
88ABC transporters_Homo sapiens_hsa020100.41017415
89African trypanosomiasis_Homo sapiens_hsa051430.38986572
90Toxoplasmosis_Homo sapiens_hsa051450.38823296
91Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.38619258
92Olfactory transduction_Homo sapiens_hsa047400.38610774
93Long-term potentiation_Homo sapiens_hsa047200.38338546
94RNA degradation_Homo sapiens_hsa030180.33106153
95Selenocompound metabolism_Homo sapiens_hsa004500.31268977
96Malaria_Homo sapiens_hsa051440.30833695
97Purine metabolism_Homo sapiens_hsa002300.30491457
98Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28970814
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.27772597
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.27598155
101Nicotine addiction_Homo sapiens_hsa050330.26771222
102TNF signaling pathway_Homo sapiens_hsa046680.25898195
103Endocytosis_Homo sapiens_hsa041440.25474613
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.24556357
105Rap1 signaling pathway_Homo sapiens_hsa040150.24375543
106Chemical carcinogenesis_Homo sapiens_hsa052040.24164390
107Tuberculosis_Homo sapiens_hsa051520.24081674
108Fanconi anemia pathway_Homo sapiens_hsa034600.22796702
109Peroxisome_Homo sapiens_hsa041460.21896088
110Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.21786216
111Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21720300
112Primary bile acid biosynthesis_Homo sapiens_hsa001200.20763693
113Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.19975420
114mRNA surveillance pathway_Homo sapiens_hsa030150.19850148
115Sulfur relay system_Homo sapiens_hsa041220.19226877
116VEGF signaling pathway_Homo sapiens_hsa043700.18734535
117Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.16553693
118Tryptophan metabolism_Homo sapiens_hsa003800.16215053
119Pentose phosphate pathway_Homo sapiens_hsa000300.15717499
120Folate biosynthesis_Homo sapiens_hsa007900.14529534
121Morphine addiction_Homo sapiens_hsa050320.14393671
122Butanoate metabolism_Homo sapiens_hsa006500.13222116
123Hepatitis C_Homo sapiens_hsa051600.12779919
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12730288
125Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.12347562
126Glucagon signaling pathway_Homo sapiens_hsa049220.11030167
127Pancreatic secretion_Homo sapiens_hsa049720.10821733
128FoxO signaling pathway_Homo sapiens_hsa040680.10535791
129Tyrosine metabolism_Homo sapiens_hsa003500.10340690
130Phagosome_Homo sapiens_hsa041450.10117732
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.10021245
132Renal cell carcinoma_Homo sapiens_hsa052110.09716755
133Drug metabolism - other enzymes_Homo sapiens_hsa009830.09690250
134Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09042833
135GABAergic synapse_Homo sapiens_hsa047270.08919988
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.07687527
137Prostate cancer_Homo sapiens_hsa052150.07364393
138Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.07328358
139Homologous recombination_Homo sapiens_hsa034400.06822411
140Non-small cell lung cancer_Homo sapiens_hsa052230.05927599
141Base excision repair_Homo sapiens_hsa034100.05456513
142Endometrial cancer_Homo sapiens_hsa052130.04656933
143Thyroid cancer_Homo sapiens_hsa052160.04246203

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