TRBJ1-2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)9.51305990
2negative thymic T cell selection (GO:0045060)8.66355810
3positive regulation of gamma-delta T cell activation (GO:0046645)8.39665075
4cytidine deamination (GO:0009972)7.81824240
5cytidine metabolic process (GO:0046087)7.81824240
6cytidine catabolic process (GO:0006216)7.81824240
7regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450917.61759962
8regulation of T cell tolerance induction (GO:0002664)7.53764454
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.23512718
10negative regulation of cell killing (GO:0031342)7.23512718
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)7.18237952
12interferon-gamma production (GO:0032609)7.08092331
13thymic T cell selection (GO:0045061)7.06801553
14positive T cell selection (GO:0043368)7.06043437
15pyrimidine ribonucleoside catabolic process (GO:0046133)6.97808643
16regulation of gamma-delta T cell differentiation (GO:0045586)6.84318206
17T cell selection (GO:0045058)6.76755044
18positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.57944215
19antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.56632726
20antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.56632726
21regulation of isotype switching to IgG isotypes (GO:0048302)6.47694416
22positive thymic T cell selection (GO:0045059)6.46108128
23positive regulation of tolerance induction (GO:0002645)6.17312683
24actin nucleation (GO:0045010)6.14003753
25negative regulation by host of viral transcription (GO:0043922)6.12461121
26regulation of gamma-delta T cell activation (GO:0046643)6.12253946
27T cell receptor signaling pathway (GO:0050852)6.06488513
28response to interleukin-15 (GO:0070672)5.79902937
29cellular response to interleukin-15 (GO:0071350)5.76833453
30T cell migration (GO:0072678)5.76542250
31DNA deamination (GO:0045006)5.74027045
32positive regulation of alpha-beta T cell proliferation (GO:0046641)5.55209065
33T cell costimulation (GO:0031295)5.50640521
34antigen processing and presentation of endogenous antigen (GO:0019883)5.45840159
35regulation of alpha-beta T cell proliferation (GO:0046640)5.44322008
36regulation of tolerance induction (GO:0002643)5.41126787
37lymphocyte costimulation (GO:0031294)5.40780325
38negative regulation of T cell apoptotic process (GO:0070233)5.33434627
39leukocyte aggregation (GO:0070486)5.21493066
40antigen receptor-mediated signaling pathway (GO:0050851)5.07133017
41eosinophil chemotaxis (GO:0048245)5.05628366
42activated T cell proliferation (GO:0050798)4.91469409
43regulation of natural killer cell mediated immunity (GO:0002715)4.85503448
44regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.85503448
45regulation of activation of Janus kinase activity (GO:0010533)4.81046717
46regulation of lymphocyte chemotaxis (GO:1901623)4.80385952
47regulation of T cell receptor signaling pathway (GO:0050856)4.78066726
48mast cell activation (GO:0045576)4.77184959
49signal complex assembly (GO:0007172)4.77028711
50positive regulation of T cell chemotaxis (GO:0010820)4.75969552
51regulation of T cell chemotaxis (GO:0010819)4.75969552
52regulation of interleukin-2 biosynthetic process (GO:0045076)4.70092823
53positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.67306944
54positive regulation of natural killer cell mediated immunity (GO:0002717)4.67306944
55regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.63225320
56negative regulation of B cell proliferation (GO:0030889)4.60612151
57regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.57803576
58eosinophil migration (GO:0072677)4.56494167
59regulation of chronic inflammatory response (GO:0002676)4.50594750
60regulation of B cell receptor signaling pathway (GO:0050855)4.48607861
61positive regulation of interleukin-2 production (GO:0032743)4.24135217
62positive regulation of monocyte chemotaxis (GO:0090026)4.23780558
63monocyte chemotaxis (GO:0002548)4.16511822
64ribosomal small subunit assembly (GO:0000028)4.14575633
65positive regulation of B cell mediated immunity (GO:0002714)4.10077888
66positive regulation of immunoglobulin mediated immune response (GO:0002891)4.10077888
67antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.09743892
68negative regulation of T cell mediated immunity (GO:0002710)4.07735142
69regulation of regulatory T cell differentiation (GO:0045589)4.07362909
70positive regulation of B cell differentiation (GO:0045579)4.06686645
71positive regulation of isotype switching (GO:0045830)4.05001603
72V(D)J recombination (GO:0033151)4.02014193
73positive regulation of lymphocyte migration (GO:2000403)3.98378941
74positive regulation of humoral immune response (GO:0002922)3.96689803
75regulation of leukocyte mediated cytotoxicity (GO:0001910)3.95002482
76positive regulation of immune response to tumor cell (GO:0002839)3.94818835
77regulation of immune response to tumor cell (GO:0002837)3.94818835
78regulation of response to tumor cell (GO:0002834)3.94818835
79positive regulation of response to tumor cell (GO:0002836)3.94818835
80positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.90014040
81sequestering of actin monomers (GO:0042989)3.85815753
82T cell differentiation (GO:0030217)3.83904264
83macrophage chemotaxis (GO:0048246)3.79910104
84regulation of T cell apoptotic process (GO:0070232)3.79390110
85natural killer cell differentiation (GO:0001779)3.77673087
86positive regulation of T cell apoptotic process (GO:0070234)3.76317606
87positive regulation of macrophage differentiation (GO:0045651)3.73660721
88cellular response to interleukin-4 (GO:0071353)3.72805667
89regulation of immunoglobulin mediated immune response (GO:0002889)3.71751973
90negative regulation of viral transcription (GO:0032897)3.70817769
91negative regulation of T cell receptor signaling pathway (GO:0050860)3.68512334
92T cell activation (GO:0042110)3.65821961
93regulation of isotype switching (GO:0045191)3.65424827
94regulation of cell killing (GO:0031341)3.64873581
95regulation of mononuclear cell migration (GO:0071675)3.62405643
96positive regulation of cell killing (GO:0031343)3.61727183
97alpha-beta T cell differentiation (GO:0046632)3.61688736
98regulation of ruffle assembly (GO:1900027)3.61621282
99antigen processing and presentation via MHC class Ib (GO:0002475)3.60915520
100regulation of B cell mediated immunity (GO:0002712)3.60382576
101negative regulation of alpha-beta T cell activation (GO:0046636)3.60378661
102regulation of chemokine-mediated signaling pathway (GO:0070099)3.59271566
103mast cell activation involved in immune response (GO:0002279)3.58828343
104mast cell degranulation (GO:0043303)3.58828343
105negative regulation of viral genome replication (GO:0045071)3.58772120
106alpha-beta T cell activation (GO:0046631)3.58584361
107positive regulation of interleukin-4 production (GO:0032753)3.58217972
108negative regulation of lymphocyte apoptotic process (GO:0070229)3.55560705
109immune response-activating cell surface receptor signaling pathway (GO:0002429)3.53887229
110modulation by host of symbiont transcription (GO:0052472)3.53106122
111modulation by host of viral transcription (GO:0043921)3.53106122
112positive regulation of uterine smooth muscle contraction (GO:0070474)3.52808271
113positive regulation of calcium-mediated signaling (GO:0050850)3.51741870
114positive regulation of immunoglobulin production (GO:0002639)3.49605690
115positive regulation of DNA recombination (GO:0045911)3.48777850
116positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.48620990
117pyrimidine nucleoside catabolic process (GO:0046135)3.48239016
118regulation of macrophage chemotaxis (GO:0010758)3.48180658
119negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.46492050
120lymphocyte migration (GO:0072676)3.46438878
121NIK/NF-kappaB signaling (GO:0038061)3.46228103
122negative regulation of B cell activation (GO:0050869)3.42661098
123regulation of calcium-mediated signaling (GO:0050848)3.41811821
124modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)3.40637512
125positive regulation of translational initiation (GO:0045948)3.39593179
126sperm capacitation (GO:0048240)3.39461875
127protein-chromophore linkage (GO:0018298)3.37975037
128negative regulation of lymphocyte mediated immunity (GO:0002707)3.37316319
129regulation of interleukin-4 production (GO:0032673)3.36220746
130leukocyte cell-cell adhesion (GO:0007159)3.33323660
131positive regulation of T cell migration (GO:2000406)3.32777153
132negative regulation of stress fiber assembly (GO:0051497)3.31744894
133T cell homeostasis (GO:0043029)3.30949583
134response to interleukin-4 (GO:0070670)3.30384138
135regulation of response to interferon-gamma (GO:0060330)3.29744446
136regulation of immunoglobulin production (GO:0002637)3.29561101
137positive regulation of lamellipodium assembly (GO:0010592)3.28328784
138regulation of interleukin-2 production (GO:0032663)3.25969657
139regulation of lymphocyte migration (GO:2000401)3.25458949
140regulation of interleukin-12 biosynthetic process (GO:0045075)3.22460456
141regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.21874361
142cytolysis (GO:0019835)3.20282747
143regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.19262879
144regulation of T cell migration (GO:2000404)3.18479121
145Arp2/3 complex-mediated actin nucleation (GO:0034314)3.16774855
146natural killer cell activation (GO:0030101)3.16708117
147positive regulation of T cell activation (GO:0050870)3.15194413
148regulation of defense response to virus by virus (GO:0050690)3.14275434
149multicellular organism reproduction (GO:0032504)3.13846946
150positive regulation of T cell cytokine production (GO:0002726)3.13421591
151B cell receptor signaling pathway (GO:0050853)3.12888978
152T cell proliferation (GO:0042098)3.08498163
153positive regulation of lymphocyte mediated immunity (GO:0002708)3.08004204
154regulation of B cell differentiation (GO:0045577)3.04082388

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.94456116
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.23031604
3E2F7_22180533_ChIP-Seq_HELA_Human5.50139452
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.72975089
5RUNX_20019798_ChIP-Seq_JUKART_Human3.71309081
6STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.65077048
7FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.54232831
8MYC_22102868_ChIP-Seq_BL_Human3.47258947
9STAT4_19710469_ChIP-ChIP_TH1__Mouse3.42258099
10MYB_26560356_Chip-Seq_TH2_Human3.33637392
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.32675062
12IRF8_22096565_ChIP-ChIP_GC-B_Human3.31075386
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.94842557
14MAF_26560356_Chip-Seq_TH1_Human2.92031173
15UTX_26944678_Chip-Seq_JUKART_Human2.80056739
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.71015828
17MYB_26560356_Chip-Seq_TH1_Human2.60210998
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.53626416
19GATA3_27048872_Chip-Seq_THYMUS_Human2.31831152
20BP1_19119308_ChIP-ChIP_Hs578T_Human2.20549956
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.15856878
22IRF8_21731497_ChIP-ChIP_J774_Mouse2.12722798
23VDR_21846776_ChIP-Seq_THP-1_Human2.08981803
24MAF_26560356_Chip-Seq_TH2_Human2.08906065
25EGR1_19374776_ChIP-ChIP_THP-1_Human2.08559075
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.00157797
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.99581906
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.96814030
29NOTCH1_21737748_ChIP-Seq_TLL_Human1.92758657
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.91248876
31RUNX1_22412390_ChIP-Seq_EML_Mouse1.89624668
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.89167718
33EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.87674378
34SPI1_23547873_ChIP-Seq_NB4_Human1.86447171
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.78630007
36SCL_19346495_ChIP-Seq_HPC-7_Human1.71691429
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.71690537
38NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.69663483
39FOXM1_23109430_ChIP-Seq_U2OS_Human1.69513193
40MYB_21317192_ChIP-Seq_ERMYB_Mouse1.69024578
41TCF7_22412390_ChIP-Seq_EML_Mouse1.66201632
42RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.61298349
43SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.60831050
44CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.60308189
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59931752
46VDR_24763502_ChIP-Seq_THP-1_Human1.54929206
47NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.50199506
48MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.48709858
49IRF8_27001747_Chip-Seq_BMDM_Mouse1.48393532
50KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.48323577
51BCL6_27268052_Chip-Seq_Bcells_Human1.47052556
52KDM2B_26808549_Chip-Seq_DND41_Human1.42102140
53E2F4_17652178_ChIP-ChIP_JURKAT_Human1.41371322
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36390027
55VDR_23849224_ChIP-Seq_CD4+_Human1.34305344
56SPI1_23127762_ChIP-Seq_K562_Human1.33526726
57CIITA_25753668_ChIP-Seq_RAJI_Human1.33343164
58FOXP3_21729870_ChIP-Seq_TREG_Human1.32718607
59VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.31935256
60SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.29018087
61BRD4_27068464_Chip-Seq_AML-cells_Mouse1.28388058
62GATA3_26560356_Chip-Seq_TH2_Human1.27884000
63RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.20399829
64GATA2_22383799_ChIP-Seq_G1ME_Mouse1.19703629
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19224856
66GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.17509663
67ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.17347279
68EGR1_19032775_ChIP-ChIP_M12_Human1.16395038
69NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.13606521
70EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.12311511
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.11478190
72BCOR_27268052_Chip-Seq_Bcells_Human1.10773120
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09135418
74ELK1_19687146_ChIP-ChIP_HELA_Human1.09040516
75EST1_17652178_ChIP-ChIP_JURKAT_Human1.06339120
76PU_27001747_Chip-Seq_BMDM_Mouse1.04474234
77GATA3_26560356_Chip-Seq_TH1_Human1.01807941
78LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.01413988
79GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00383940
80PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00020257
81TAF15_26573619_Chip-Seq_HEK293_Human0.99549654
82SMAD_19615063_ChIP-ChIP_OVARY_Human0.98297636
83SPI1_20517297_ChIP-Seq_HL60_Human0.98154890
84NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97760186
85P300_27268052_Chip-Seq_Bcells_Human0.97213039
86TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96929854
87RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96438166
88KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95345977
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94787577
90SA1_27219007_Chip-Seq_Bcells_Human0.94692587
91BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.94638421
92RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.94330259
93PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92709002
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92344508
95CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90210354
96CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90069011
97PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.89947676
98FLI1_27457419_Chip-Seq_LIVER_Mouse0.89325423
99PU.1_20513432_ChIP-Seq_Bcells_Mouse0.88861581
100GABP_17652178_ChIP-ChIP_JURKAT_Human0.88510645
101KDM2B_26808549_Chip-Seq_JURKAT_Human0.88228048
102XRN2_22483619_ChIP-Seq_HELA_Human0.87970607
103TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.87688216
104LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.87551019
105MYC_19079543_ChIP-ChIP_MESCs_Mouse0.87422922
106FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.84963941
107FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84091571
108PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.82708050
109EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.82246014
110GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.82200166
111ELK3_25401928_ChIP-Seq_HUVEC_Human0.82092307
112AR_20517297_ChIP-Seq_VCAP_Human0.80688160
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.80529498
114P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.80465092
115RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80267609
116SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.79548480
117GATA1_22383799_ChIP-Seq_G1ME_Mouse0.79184353
118FOXA1_21572438_ChIP-Seq_LNCaP_Human0.79022144
119CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78534360
120GATA1_19941827_ChIP-Seq_MEL_Mouse0.78094275
121OCT4_20526341_ChIP-Seq_ESCs_Human0.77358161
122CEBPB_22108803_ChIP-Seq_LS180_Human0.77286468
123MYC_18555785_ChIP-Seq_MESCs_Mouse0.77145456
124NANOG_20526341_ChIP-Seq_ESCs_Human0.77086239
125PCGF2_27294783_Chip-Seq_ESCs_Mouse0.76932906
126PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.75643835
127FOXA1_25329375_ChIP-Seq_VCAP_Human0.75427307
128FOXA1_27270436_Chip-Seq_PROSTATE_Human0.75427307
129TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.74604173
130CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.72593223
131ERA_21632823_ChIP-Seq_H3396_Human0.71644582
132TP53_22573176_ChIP-Seq_HFKS_Human0.71440753
133VDR_22108803_ChIP-Seq_LS180_Human0.71150181
134FOXH1_21741376_ChIP-Seq_EPCs_Human0.70863370
135EZH2_27294783_Chip-Seq_NPCs_Mouse0.70802291
136TAF2_19829295_ChIP-Seq_ESCs_Human0.70561606
137NFE2_27457419_Chip-Seq_LIVER_Mouse0.70289118
138VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.70237493
139EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.69700667
140E2F1_20622854_ChIP-Seq_HELA_Human0.68857745
141GATA6_21074721_ChIP-Seq_CACO-2_Human0.67919945
142NCOR_22424771_ChIP-Seq_293T_Human0.66955874
143GATA1_22025678_ChIP-Seq_K562_Human0.66596819
144PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.66474409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.20336633
2MP0005671_abnormal_response_to5.57396288
3MP0002638_abnormal_pupillary_reflex4.30811822
4MP0000685_abnormal_immune_system3.45550867
5MP0009333_abnormal_splenocyte_physiolog3.35379925
6MP0001835_abnormal_antigen_presentation3.34848713
7MP0000703_abnormal_thymus_morphology3.24709337
8MP0001800_abnormal_humoral_immune3.19649467
9MP0002398_abnormal_bone_marrow3.13211697
10MP0002420_abnormal_adaptive_immunity3.08105372
11MP0001819_abnormal_immune_cell3.01988075
12MP0005000_abnormal_immune_tolerance2.86855261
13MP0002166_altered_tumor_susceptibility2.82403575
14MP0002723_abnormal_immune_serum2.77723386
15MP0000716_abnormal_immune_system2.66045740
16MP0002722_abnormal_immune_system2.63811379
17MP0002405_respiratory_system_inflammati2.59214270
18MP0005387_immune_system_phenotype2.52341116
19MP0001790_abnormal_immune_system2.52341116
20MP0002452_abnormal_antigen_presenting2.52202087
21MP0009785_altered_susceptibility_to2.49406331
22MP0005025_abnormal_response_to2.47875737
23MP0000689_abnormal_spleen_morphology2.45996995
24MP0006082_CNS_inflammation2.38779195
25MP0003300_gastrointestinal_ulcer2.37289103
26MP0002006_tumorigenesis2.34991459
27MP0002138_abnormal_hepatobiliary_system2.34909212
28MP0002396_abnormal_hematopoietic_system2.28773748
29MP0003436_decreased_susceptibility_to2.27269360
30MP0002429_abnormal_blood_cell2.17058052
31MP0004947_skin_inflammation2.11507868
32MP0003724_increased_susceptibility_to2.08665247
33MP0004147_increased_porphyrin_level2.02816181
34MP0003011_delayed_dark_adaptation2.02548542
35MP0002148_abnormal_hypersensitivity_rea2.00363854
36MP0003866_abnormal_defecation1.97716647
37MP0001873_stomach_inflammation1.96947390
38MP0010155_abnormal_intestine_physiology1.95196473
39MP0002933_joint_inflammation1.94148285
40MP0004381_abnormal_hair_follicle1.91067424
41MP0002419_abnormal_innate_immunity1.85497326
42MP0005464_abnormal_platelet_physiology1.76968860
43MP0000858_altered_metastatic_potential1.75398754
44MP0001845_abnormal_inflammatory_respons1.67400041
45MP0002877_abnormal_melanocyte_morpholog1.62598661
46MP0002163_abnormal_gland_morphology1.61157734
47MP0003448_altered_tumor_morphology1.53023032
48MP0002277_abnormal_respiratory_mucosa1.48125746
49MP0005075_abnormal_melanosome_morpholog1.46057877
50MP0001502_abnormal_circadian_rhythm1.44293405
51MP0004808_abnormal_hematopoietic_stem1.44157830
52MP0000465_gastrointestinal_hemorrhage1.43526195
53MP0001853_heart_inflammation1.42682393
54MP0003183_abnormal_peptide_metabolism1.40586369
55MP0001764_abnormal_homeostasis1.38435287
56MP0001905_abnormal_dopamine_level1.37643348
57MP0000372_irregular_coat_pigmentation1.36650861
58MP0004145_abnormal_muscle_electrophysio1.27386129
59MP0002019_abnormal_tumor_incidence1.22685035
60MP0008057_abnormal_DNA_replication1.17146805
61MP0010352_gastrointestinal_tract_polyps1.15053113
62MP0000569_abnormal_digit_pigmentation1.12398074
63MP0005379_endocrine/exocrine_gland_phen1.11268046
64MP0005253_abnormal_eye_physiology1.09206380
65MP0005645_abnormal_hypothalamus_physiol1.08869463
66MP0006054_spinal_hemorrhage1.08155577
67MP0005397_hematopoietic_system_phenotyp1.06879099
68MP0001545_abnormal_hematopoietic_system1.06879099
69MP0003303_peritoneal_inflammation1.05767377
70MP0000490_abnormal_crypts_of1.04093760
71MP0010094_abnormal_chromosome_stability1.02445700
72MP0004957_abnormal_blastocyst_morpholog1.01577462
73MP0008469_abnormal_protein_level0.99219265
74MP0002139_abnormal_hepatobiliary_system0.97603505
75MP0001533_abnormal_skeleton_physiology0.96430562
76MP0004043_abnormal_pH_regulation0.96199019
77MP0001881_abnormal_mammary_gland0.95655007
78MP0004510_myositis0.93718447
79MP0003077_abnormal_cell_cycle0.92693375
80MP0002909_abnormal_adrenal_gland0.91996678
81MP0005023_abnormal_wound_healing0.90746923
82MP0001968_abnormal_touch/_nociception0.89961835
83MP0001501_abnormal_sleep_pattern0.88132217
84MP0003806_abnormal_nucleotide_metabolis0.86708565
85MP0004142_abnormal_muscle_tone0.86183814
86MP0002009_preneoplasia0.85118100
87MP0001661_extended_life_span0.84194125
88MP0009763_increased_sensitivity_to0.82484866
89MP0000371_diluted_coat_color0.82327698
90MP0002102_abnormal_ear_morphology0.81935883
91MP0001542_abnormal_bone_strength0.81820914
92MP0003045_fibrosis0.80301950
93MP0009643_abnormal_urine_homeostasis0.77762358
94MP0003137_abnormal_impulse_conducting0.75901196
95MP0003786_premature_aging0.75818598
96MP0002132_abnormal_respiratory_system0.75581894
97MP0001851_eye_inflammation0.71740643
98MP0002998_abnormal_bone_remodeling0.70708100
99MP0009765_abnormal_xenobiotic_induced0.69702861
100MP0003693_abnormal_embryo_hatching0.69233482
101MP0005310_abnormal_salivary_gland0.67459370
102MP0000604_amyloidosis0.65569015
103MP0006292_abnormal_olfactory_placode0.64804710
104MP0002168_other_aberrant_phenotype0.63488254
105MP0000015_abnormal_ear_pigmentation0.61077287
106MP0000609_abnormal_liver_physiology0.59341144
107MP0005376_homeostasis/metabolism_phenot0.58351166
108MP0000477_abnormal_intestine_morphology0.57706877
109MP0005266_abnormal_metabolism0.57157577
110MP0001243_abnormal_dermal_layer0.56461795
111MP0005174_abnormal_tail_pigmentation0.56171899
112MP0008961_abnormal_basal_metabolism0.55965677
113MP0008874_decreased_physiological_sensi0.55558424
114MP0009278_abnormal_bone_marrow0.55287422
115MP0001348_abnormal_lacrimal_gland0.55266887
116MP0008007_abnormal_cellular_replicative0.53863028
117MP0001186_pigmentation_phenotype0.53252680
118MP0008873_increased_physiological_sensi0.53098361
119MP0000920_abnormal_myelination0.52924865
120MP0002136_abnormal_kidney_physiology0.52739418
121MP0002822_catalepsy0.52638379
122MP0003646_muscle_fatigue0.52345565
123MP0001188_hyperpigmentation0.51914269
124MP0010234_abnormal_vibrissa_follicle0.51851157
125MP0002837_dystrophic_cardiac_calcinosis0.51648776
126MP0009764_decreased_sensitivity_to0.51342259
127MP0000230_abnormal_systemic_arterial0.51336257
128MP0006276_abnormal_autonomic_nervous0.50867208
129MP0002693_abnormal_pancreas_physiology0.49494206
130MP0008058_abnormal_DNA_repair0.46417090
131MP0003111_abnormal_nucleus_morphology0.46363261
132MP0002083_premature_death0.46103046
133MP0000249_abnormal_blood_vessel0.45214592
134MP0001958_emphysema0.44985329
135MP0003795_abnormal_bone_structure0.44957942
136MP0000350_abnormal_cell_proliferation0.42703900
137MP0001730_embryonic_growth_arrest0.38645444
138MP0005076_abnormal_cell_differentiation0.38642781
139MP0000313_abnormal_cell_death0.38062694
140MP0001191_abnormal_skin_condition0.37917013
141MP0005166_decreased_susceptibility_to0.36646988
142MP0000367_abnormal_coat/_hair0.36614802
143MP0003453_abnormal_keratinocyte_physiol0.36397462
144MP0005408_hypopigmentation0.35779637
145MP0008569_lethality_at_weaning0.35623377

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)9.92439389
2Abnormality of T cell number (HP:0011839)9.49769914
3Combined immunodeficiency (HP:0005387)6.22287596
4Elevated erythrocyte sedimentation rate (HP:0003565)6.21301047
5Severe combined immunodeficiency (HP:0004430)6.15296005
6Abnormality of T cells (HP:0002843)5.88506273
7Aplastic anemia (HP:0001915)5.68365035
8Recurrent viral infections (HP:0004429)5.07606198
9Eosinophilia (HP:0001880)4.79543330
10Panhypogammaglobulinemia (HP:0003139)4.74465537
11Abnormality of eosinophils (HP:0001879)4.60926171
12Chronic otitis media (HP:0000389)4.51961731
13IgG deficiency (HP:0004315)4.40176025
14Recurrent fungal infections (HP:0002841)4.29095043
15Recurrent bronchitis (HP:0002837)4.28166140
16Stomatitis (HP:0010280)4.19657348
17Myositis (HP:0100614)4.19607571
18Thyroiditis (HP:0100646)4.18307477
19Joint swelling (HP:0001386)4.14757836
20Nasal polyposis (HP:0100582)4.11071111
21Granulocytopenia (HP:0001913)4.09420020
22Autoimmune hemolytic anemia (HP:0001890)4.00121516
23Leukocytosis (HP:0001974)3.92951924
24Hypoplasia of the thymus (HP:0000778)3.63734867
25Lymphopenia (HP:0001888)3.62076159
26Pustule (HP:0200039)3.59281853
27Abnormality of cells of the lymphoid lineage (HP:0012140)3.49980413
28Acute hepatic failure (HP:0006554)3.48468836
29B lymphocytopenia (HP:0010976)3.47767498
30Abnormality of B cell number (HP:0010975)3.47767498
31Eczematoid dermatitis (HP:0000976)3.46496665
32IgM deficiency (HP:0002850)3.42484895
33Abnormality of the nasal mucosa (HP:0000433)3.40482721
34Bilateral sensorineural hearing impairment (HP:0008619)3.36931410
35Increased IgM level (HP:0003496)3.33609406
36Hemiplegia (HP:0002301)3.22492405
37Encephalitis (HP:0002383)3.19362804
38Abnormal delayed hypersensitivity skin test (HP:0002963)3.18883746
39Chronic diarrhea (HP:0002028)3.11846433
40Thrombocytosis (HP:0001894)3.07645235
41Autoimmune thrombocytopenia (HP:0001973)3.04327636
42Meningitis (HP:0001287)3.03841163
43Chronic mucocutaneous candidiasis (HP:0002728)3.00618040
44Recurrent cutaneous fungal infections (HP:0011370)3.00618040
45Abnormality of the fingertips (HP:0001211)2.93282009
46Lymphoma (HP:0002665)2.78136426
47Recurrent abscess formation (HP:0002722)2.74444618
48Recurrent otitis media (HP:0000403)2.71914345
49J-shaped sella turcica (HP:0002680)2.68782782
50Abnormality of macrophages (HP:0004311)2.68045506
51Basal cell carcinoma (HP:0002671)2.64830455
52Focal motor seizures (HP:0011153)2.64514071
53Spontaneous hematomas (HP:0007420)2.64001023
54Gastrointestinal infarctions (HP:0005244)2.63822381
55Abnormality of T cell physiology (HP:0011840)2.63693302
56Pancytopenia (HP:0001876)2.58818867
57Keratoconjunctivitis sicca (HP:0001097)2.55387860
58Sensory axonal neuropathy (HP:0003390)2.55336033
59Progressive neurologic deterioration (HP:0002344)2.54723650
603-Methylglutaconic aciduria (HP:0003535)2.53860410
61Verrucae (HP:0200043)2.52051587
62Papilloma (HP:0012740)2.52051587
63Optic neuritis (HP:0100653)2.51823191
64Retrobulbar optic neuritis (HP:0100654)2.51823191
65Hypergammaglobulinemia (HP:0010702)2.51423662
66Absent rod-and cone-mediated responses on ERG (HP:0007688)2.50906298
67Mediastinal lymphadenopathy (HP:0100721)2.49866001
68Abnormal albumin level (HP:0012116)2.48656568
69Hypoalbuminemia (HP:0003073)2.48656568
70Bronchitis (HP:0012387)2.48529373
71Severe visual impairment (HP:0001141)2.45912193
72Abnormality of oral frenula (HP:0000190)2.44894439
73Chronic sinusitis (HP:0011109)2.43675403
74Visual hallucinations (HP:0002367)2.39703169
75Abnormal platelet volume (HP:0011876)2.39676501
76Orchitis (HP:0100796)2.38899329
77Keratoconjunctivitis (HP:0001096)2.28205768
78Agammaglobulinemia (HP:0004432)2.24452446
79Hemoptysis (HP:0002105)2.21897985
80Recurrent skin infections (HP:0001581)2.21103685
81Cerebral hypomyelination (HP:0006808)2.20211580
82Abnormal rod and cone electroretinograms (HP:0008323)2.17521756
83Recurrent sinusitis (HP:0011108)2.17481185
84Amaurosis fugax (HP:0100576)2.16749657
85Vasculitis (HP:0002633)2.13993786
86Ureteral obstruction (HP:0006000)2.12993716
87Increased mean platelet volume (HP:0011877)2.09777576
88Abolished electroretinogram (ERG) (HP:0000550)2.08189421
89Trigonocephaly (HP:0000243)2.07932479
90Cellular immunodeficiency (HP:0005374)2.07881858
91Chronic obstructive pulmonary disease (HP:0006510)2.07691260
92Obstructive lung disease (HP:0006536)2.07691260
93Epistaxis (HP:0000421)2.07088234
94Gastrointestinal inflammation (HP:0004386)2.06663336
95Slow saccadic eye movements (HP:0000514)2.06276031
96Inflammation of the large intestine (HP:0002037)2.06226586
97Pulmonary infiltrates (HP:0002113)2.06021049
98Recurrent bacterial skin infections (HP:0005406)2.05644532
99Aplasia/Hypoplasia of the thymus (HP:0010515)2.05414041
100Increased IgE level (HP:0003212)2.02987574
101Gangrene (HP:0100758)2.00130667
10211 pairs of ribs (HP:0000878)1.97939943
103Arterial thrombosis (HP:0004420)1.96853719
104Pulmonary embolism (HP:0002204)1.96097121
105Abnormality of the prostate (HP:0008775)1.93938671
106Skin rash (HP:0000988)1.93051524
107Hypoproteinemia (HP:0003075)1.90146295
108Prolonged bleeding time (HP:0003010)1.89711399
109Bronchiectasis (HP:0002110)1.85311027
110Multiple enchondromatosis (HP:0005701)1.84759773
111Chest pain (HP:0100749)1.83299472
112Aplasia/Hypoplasia of the macula (HP:0008059)1.82735826
113Petechiae (HP:0000967)1.82075204
114Colon cancer (HP:0003003)1.81643299
115Bicuspid aortic valve (HP:0001647)1.79103768
116Renal cortical cysts (HP:0000803)1.78086032
117Conical tooth (HP:0000698)1.77747123
118Increased neuronal autofluorescent lipopigment (HP:0002074)1.76755887
119Dislocated radial head (HP:0003083)1.75653078
120Periodontitis (HP:0000704)1.75559538
121Congenital stationary night blindness (HP:0007642)1.73510727
122Gingival bleeding (HP:0000225)1.73450417
123Poor speech (HP:0002465)1.73218582
124Type I transferrin isoform profile (HP:0003642)1.72524163
125Abnormality of dentin (HP:0010299)1.72235567
126Oral leukoplakia (HP:0002745)1.71807043
127Aplasia/Hypoplasia affecting the retina (HP:0008061)1.71127795
128Periorbital edema (HP:0100539)1.70953692
129Skin ulcer (HP:0200042)1.69700068
130Recurrent pneumonia (HP:0006532)1.69442269
131Broad palm (HP:0001169)1.69234852
132IgA deficiency (HP:0002720)1.68422599
133Abnormality of the pleura (HP:0002103)1.66412085
134Ureteral stenosis (HP:0000071)1.62859909

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.85640478
2MAP4K16.12082623
3ITK3.39187712
4ZAP703.25632201
5STK103.07738088
6CDK192.83333477
7MST42.66320686
8JAK32.48115170
9GRK62.43680252
10TESK12.35356727
11FGFR42.15221381
12NLK2.13211066
13TYK22.08828577
14LCK2.07632291
15MAP3K111.91064143
16TEC1.87684640
17EEF2K1.82842185
18CSK1.82500794
19IKBKE1.80264291
20JAK11.75796744
21SYK1.72194298
22GRK71.69363828
23LIMK11.64012826
24LRRK21.49729061
25BTK1.48763415
26MAP3K141.45279601
27ZAK1.44455858
28TESK21.43777954
29CLK11.40064570
30FGFR31.37324376
31MAP3K101.35986273
32PKN21.32289628
33MAP3K131.31352532
34MAP4K21.25182282
35GRK11.23626590
36BCKDK1.22838809
37PRKCH1.22398144
38CAMKK21.22267728
39HCK1.19869224
40PRKCQ1.18503687
41MYLK1.16609843
42SCYL21.14700150
43NME21.13567398
44KDR1.08161824
45BLK1.01502569
46TBK11.00759386
47MARK30.93683256
48KIT0.93655421
49PIM10.92347930
50SIK20.91758365
51SIK10.91644840
52PASK0.89197839
53MAP3K70.88587217
54LYN0.86210275
55MAP3K30.86051645
56FES0.84824475
57EPHB10.83469931
58DAPK10.82440428
59TRPM70.82270551
60RIPK40.76278232
61FGR0.74548581
62PRPF4B0.74315255
63FGFR10.72816872
64TSSK60.71103564
65IRAK20.70026754
66VRK10.69307108
67CDK40.69039927
68FYN0.68010794
69NEK10.66026593
70STK40.65879811
71CSF1R0.64362385
72IKBKB0.62123773
73JAK20.62025727
74CDC70.61270507
75MELK0.57215792
76RPS6KA40.56562824
77MAP3K120.56334718
78TGFBR10.56219510
79PDGFRB0.55449988
80BMPR20.54666366
81INSR0.52575280
82SIK30.52574165
83IGF1R0.51775268
84MAPKAPK30.51591050
85RPS6KB20.50048511
86MARK20.49894819
87FLT30.48582724
88TAOK30.48544465
89PDK10.47125278
90TLK10.46258423
91ROCK10.45837138
92TGFBR20.45828083
93IRAK40.44896599
94HIPK20.41806566
95FGFR20.41207363
96CAMKK10.40749421
97MAPKAPK20.40745648
98MAPK70.39930669
99MAPK40.38781219
100MAP2K60.38332086
101TAOK20.37927592
102MAP3K80.37032595
103RPS6KA50.36853168
104EPHA30.36116519
105MAPK120.31800585
106PRKG20.31605809
107ALK0.31585973
108CDK60.30689683
109ILK0.30336471
110GRK50.29740684
111RPS6KA60.29563556
112MAPK110.29476186
113PIK3CG0.29358243
114IRAK10.29102474
115TNK20.28126667
116PRKACA0.27579536
117TYRO30.27532295
118WNK40.26290624
119TRIB30.25688380
120ROCK20.24514711
121MAPK30.24049446
122DYRK1B0.23637892
123NTRK20.23498813
124CHUK0.23248909
125ADRBK20.22206287
126RPS6KC10.20803933
127RPS6KL10.20803933
128AURKA0.20776583
129TTN0.20668365
130PRKAA10.20416870
131ERBB30.20071037
132PTK60.18964064
133SRC0.18766012
134ABL10.18427848
135BUB10.18382620
136NEK60.18266421
137MAPK90.18153820
138PRKCA0.17599233
139ATR0.17398102
140SRPK10.17381280
141MAP2K30.16456677
142TAOK10.16310327
143NEK20.16285395
144CDK120.16184453
145OBSCN0.14603421

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.18104438
2Graft-versus-host disease_Homo sapiens_hsa053324.66387826
3T cell receptor signaling pathway_Homo sapiens_hsa046604.51351849
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.89543406
5Antigen processing and presentation_Homo sapiens_hsa046123.13712955
6Measles_Homo sapiens_hsa051622.94106434
7Hematopoietic cell lineage_Homo sapiens_hsa046402.93870764
8Allograft rejection_Homo sapiens_hsa053302.56323321
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.34179914
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.30590030
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.15218762
12Non-homologous end-joining_Homo sapiens_hsa034501.92111090
13Ribosome_Homo sapiens_hsa030101.85272004
14Viral myocarditis_Homo sapiens_hsa054161.76350395
15Type I diabetes mellitus_Homo sapiens_hsa049401.75134738
16Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.59475557
17Autoimmune thyroid disease_Homo sapiens_hsa053201.57453342
18Phototransduction_Homo sapiens_hsa047441.56835772
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.55539360
20Leishmaniasis_Homo sapiens_hsa051401.52693071
21Leukocyte transendothelial migration_Homo sapiens_hsa046701.49304062
22Osteoclast differentiation_Homo sapiens_hsa043801.44309853
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.37361355
24Herpes simplex infection_Homo sapiens_hsa051681.32317994
25Oxidative phosphorylation_Homo sapiens_hsa001901.30736382
26Chemokine signaling pathway_Homo sapiens_hsa040621.29141635
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.26936333
28Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.25217550
29B cell receptor signaling pathway_Homo sapiens_hsa046621.23607247
30DNA replication_Homo sapiens_hsa030301.23405966
31SNARE interactions in vesicular transport_Homo sapiens_hsa041301.22076755
32HTLV-I infection_Homo sapiens_hsa051661.21260693
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17559675
34Parkinsons disease_Homo sapiens_hsa050121.16577402
35RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14655376
36Mismatch repair_Homo sapiens_hsa034301.13842702
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08114103
38Colorectal cancer_Homo sapiens_hsa052101.06485748
39Hepatitis B_Homo sapiens_hsa051611.05853870
40Acute myeloid leukemia_Homo sapiens_hsa052211.05418333
41Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04505370
42Spliceosome_Homo sapiens_hsa030401.04335697
43NOD-like receptor signaling pathway_Homo sapiens_hsa046211.03512944
44Shigellosis_Homo sapiens_hsa051311.01485635
45Toxoplasmosis_Homo sapiens_hsa051451.01011861
46Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.00887340
47Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00062640
48Olfactory transduction_Homo sapiens_hsa047400.96721510
49Apoptosis_Homo sapiens_hsa042100.90263480
50Influenza A_Homo sapiens_hsa051640.88401394
51Viral carcinogenesis_Homo sapiens_hsa052030.87733533
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86233071
53Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.84226485
54Regulation of autophagy_Homo sapiens_hsa041400.83631352
55Epstein-Barr virus infection_Homo sapiens_hsa051690.81347895
56Alzheimers disease_Homo sapiens_hsa050100.80927209
57Retinol metabolism_Homo sapiens_hsa008300.77649293
58Pancreatic cancer_Homo sapiens_hsa052120.76178691
59Platelet activation_Homo sapiens_hsa046110.75269654
60TNF signaling pathway_Homo sapiens_hsa046680.74049845
61Prion diseases_Homo sapiens_hsa050200.72824430
62Asthma_Homo sapiens_hsa053100.72732948
63Legionellosis_Homo sapiens_hsa051340.71766070
64Peroxisome_Homo sapiens_hsa041460.66922045
65Base excision repair_Homo sapiens_hsa034100.66573657
66Systemic lupus erythematosus_Homo sapiens_hsa053220.66355914
67Salmonella infection_Homo sapiens_hsa051320.65232757
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.65171846
69Proteasome_Homo sapiens_hsa030500.64019316
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62389121
71Chronic myeloid leukemia_Homo sapiens_hsa052200.60532591
72Staphylococcus aureus infection_Homo sapiens_hsa051500.60018761
73Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.59672337
74Hepatitis C_Homo sapiens_hsa051600.57190248
75Toll-like receptor signaling pathway_Homo sapiens_hsa046200.56415485
76Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.55075030
77VEGF signaling pathway_Homo sapiens_hsa043700.53887661
78Chemical carcinogenesis_Homo sapiens_hsa052040.53214625
79Linoleic acid metabolism_Homo sapiens_hsa005910.53183394
80Cardiac muscle contraction_Homo sapiens_hsa042600.51907155
81Rheumatoid arthritis_Homo sapiens_hsa053230.51815627
82Huntingtons disease_Homo sapiens_hsa050160.51686030
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50423063
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49859749
85Tuberculosis_Homo sapiens_hsa051520.49371756
86Pentose phosphate pathway_Homo sapiens_hsa000300.47905859
87Nucleotide excision repair_Homo sapiens_hsa034200.47470310
88Malaria_Homo sapiens_hsa051440.46800106
89Protein export_Homo sapiens_hsa030600.45820108
90Non-small cell lung cancer_Homo sapiens_hsa052230.45244516
91Endocytosis_Homo sapiens_hsa041440.44750769
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42874621
93RNA degradation_Homo sapiens_hsa030180.41142557
94Morphine addiction_Homo sapiens_hsa050320.40010435
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39613845
96African trypanosomiasis_Homo sapiens_hsa051430.39544378
97Thyroid cancer_Homo sapiens_hsa052160.39492215
98p53 signaling pathway_Homo sapiens_hsa041150.39045598
99Pertussis_Homo sapiens_hsa051330.38457379
100Notch signaling pathway_Homo sapiens_hsa043300.38110068
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36658190
102Basal transcription factors_Homo sapiens_hsa030220.34543521
103Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.33623274
104RNA transport_Homo sapiens_hsa030130.33560605
105Small cell lung cancer_Homo sapiens_hsa052220.33489488
106Cell cycle_Homo sapiens_hsa041100.33268541
107Taste transduction_Homo sapiens_hsa047420.33251522
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.32312700
109Steroid hormone biosynthesis_Homo sapiens_hsa001400.31732418
110mRNA surveillance pathway_Homo sapiens_hsa030150.30314657
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.29187779
112Rap1 signaling pathway_Homo sapiens_hsa040150.28052289
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.27098389
114Prostate cancer_Homo sapiens_hsa052150.26809514
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26766061
116Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.26477368
117Homologous recombination_Homo sapiens_hsa034400.25125190
118FoxO signaling pathway_Homo sapiens_hsa040680.23901365
119Prolactin signaling pathway_Homo sapiens_hsa049170.23765171
120Endometrial cancer_Homo sapiens_hsa052130.23729253
121Adherens junction_Homo sapiens_hsa045200.17718303
122Insulin resistance_Homo sapiens_hsa049310.17296917
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.15990622
124Caffeine metabolism_Homo sapiens_hsa002320.15282092
125MicroRNAs in cancer_Homo sapiens_hsa052060.15217986
126mTOR signaling pathway_Homo sapiens_hsa041500.14826727
127Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.14258105
128Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.13656930
129Ether lipid metabolism_Homo sapiens_hsa005650.13048607
130One carbon pool by folate_Homo sapiens_hsa006700.12969845
131Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.12866117
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.12249834
133MAPK signaling pathway_Homo sapiens_hsa040100.11502722
134Pathways in cancer_Homo sapiens_hsa052000.08853126
135Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.08709956
136Folate biosynthesis_Homo sapiens_hsa007900.08689499
137Vascular smooth muscle contraction_Homo sapiens_hsa042700.08378277
138Phagosome_Homo sapiens_hsa041450.07557983
139Fanconi anemia pathway_Homo sapiens_hsa034600.05824053
140Calcium signaling pathway_Homo sapiens_hsa040200.05039143
141Vitamin digestion and absorption_Homo sapiens_hsa049770.04385978
142Glycerophospholipid metabolism_Homo sapiens_hsa005640.02450086

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