TRAPPC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)8.06091136
2ribosomal small subunit assembly (GO:0000028)7.79534962
3translational termination (GO:0006415)7.69991434
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.78976187
5ribosomal small subunit biogenesis (GO:0042274)6.77129855
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.76171384
7cotranslational protein targeting to membrane (GO:0006613)6.72227655
8translational elongation (GO:0006414)6.66847362
9protein targeting to ER (GO:0045047)6.64164168
10energy coupled proton transport, down electrochemical gradient (GO:0015985)6.43317098
11ATP synthesis coupled proton transport (GO:0015986)6.43317098
12protein localization to endoplasmic reticulum (GO:0070972)6.35560992
13establishment of protein localization to endoplasmic reticulum (GO:0072599)6.34851440
14maturation of SSU-rRNA (GO:0030490)6.06031075
15cellular protein complex disassembly (GO:0043624)6.02930288
16viral life cycle (GO:0019058)5.97721407
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.69085922
18ribosomal large subunit biogenesis (GO:0042273)5.68839888
19translational initiation (GO:0006413)5.57107040
20mitochondrial respiratory chain complex I assembly (GO:0032981)5.24482083
21NADH dehydrogenase complex assembly (GO:0010257)5.24482083
22mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.24482083
23protein complex disassembly (GO:0043241)5.20672402
24mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.04994156
25macromolecular complex disassembly (GO:0032984)4.94914616
26protein complex biogenesis (GO:0070271)4.92178931
27respiratory electron transport chain (GO:0022904)4.90306006
28electron transport chain (GO:0022900)4.83347695
29behavioral response to nicotine (GO:0035095)4.81240667
30DNA deamination (GO:0045006)4.78098046
31mitochondrial respiratory chain complex assembly (GO:0033108)4.67637043
32translation (GO:0006412)4.52298703
33chaperone-mediated protein transport (GO:0072321)4.47918873
34protein targeting to membrane (GO:0006612)4.42654328
35GTP biosynthetic process (GO:0006183)4.41641157
36deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.19623006
37nuclear-transcribed mRNA catabolic process (GO:0000956)4.13991349
38proteasome assembly (GO:0043248)4.12524027
39mRNA catabolic process (GO:0006402)3.92783439
40UTP biosynthetic process (GO:0006228)3.92539059
41respiratory chain complex IV assembly (GO:0008535)3.89819620
42guanosine-containing compound biosynthetic process (GO:1901070)3.89209659
43ribonucleoprotein complex biogenesis (GO:0022613)3.87460076
44cellular component biogenesis (GO:0044085)3.85179896
45platelet dense granule organization (GO:0060155)3.69485596
46pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.69380125
47transcription elongation from RNA polymerase III promoter (GO:0006385)3.65019335
48termination of RNA polymerase III transcription (GO:0006386)3.65019335
49RNA catabolic process (GO:0006401)3.60482964
50inner mitochondrial membrane organization (GO:0007007)3.60378578
51base-excision repair, AP site formation (GO:0006285)3.56667133
52oxidative phosphorylation (GO:0006119)3.56110156
53regulation of mitochondrial translation (GO:0070129)3.53461641
54UTP metabolic process (GO:0046051)3.52594989
55CTP biosynthetic process (GO:0006241)3.49937226
56CTP metabolic process (GO:0046036)3.49937226
57positive regulation of prostaglandin secretion (GO:0032308)3.48356181
58negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.47440018
59L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.45634535
60purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.45046017
61purine deoxyribonucleotide catabolic process (GO:0009155)3.44559863
62polyketide metabolic process (GO:0030638)3.41970458
63doxorubicin metabolic process (GO:0044598)3.41970458
64daunorubicin metabolic process (GO:0044597)3.41970458
65purine nucleoside triphosphate biosynthetic process (GO:0009145)3.40097323
66dopamine transport (GO:0015872)3.38975860
67DNA strand elongation involved in DNA replication (GO:0006271)3.37631550
68protein targeting to mitochondrion (GO:0006626)3.35156420
69pseudouridine synthesis (GO:0001522)3.34213611
70establishment of protein localization to mitochondrial membrane (GO:0090151)3.33267408
71telomere maintenance via semi-conservative replication (GO:0032201)3.32923312
72DNA damage response, detection of DNA damage (GO:0042769)3.32377342
73establishment of integrated proviral latency (GO:0075713)3.31642621
74negative regulation of telomere maintenance (GO:0032205)3.30354898
75mannosylation (GO:0097502)3.24706460
76negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.23286358
77negative regulation of ligase activity (GO:0051352)3.23286358
78rRNA processing (GO:0006364)3.23036906
79ubiquinone biosynthetic process (GO:0006744)3.22151209
80establishment of protein localization to membrane (GO:0090150)3.20289374
81pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.20042616
82autophagic vacuole fusion (GO:0000046)3.19891292
83DNA strand elongation (GO:0022616)3.19647335
84ribonucleoside triphosphate biosynthetic process (GO:0009201)3.18225968
85protein targeting (GO:0006605)3.17504586
86ATP biosynthetic process (GO:0006754)3.17447405
87establishment of protein localization to mitochondrion (GO:0072655)3.17237003
88cellular response to interferon-beta (GO:0035458)3.15354342
89hydrogen ion transmembrane transport (GO:1902600)3.14117271
90rRNA metabolic process (GO:0016072)3.11004639
91pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.10449277
92spliceosomal snRNP assembly (GO:0000387)3.10344166
93cytochrome complex assembly (GO:0017004)3.08170710
94tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.07042189
95RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.07042189
96response to misfolded protein (GO:0051788)3.05929597
97aerobic respiration (GO:0009060)3.04803493
98regulation of cellular amino acid metabolic process (GO:0006521)3.03679123
99peptidyl-histidine modification (GO:0018202)3.03674684
100deoxyribose phosphate catabolic process (GO:0046386)3.03340390
101antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.02925855
102iron-sulfur cluster assembly (GO:0016226)3.02845970
103metallo-sulfur cluster assembly (GO:0031163)3.02845970
104positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.02709676
105response to interferon-beta (GO:0035456)3.02533491
106deoxyribonucleotide catabolic process (GO:0009264)3.01078032
107DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.00852973
108pyrimidine nucleotide catabolic process (GO:0006244)2.99717598
109pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.98889279
110water-soluble vitamin biosynthetic process (GO:0042364)2.98282677
111exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.98031776
112spliceosomal complex assembly (GO:0000245)2.96461237
113negative regulation of B cell apoptotic process (GO:0002903)2.96203616
114regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.94990373
115pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.94615591
116protein localization to mitochondrion (GO:0070585)2.94054540
117nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.92156041
118proton transport (GO:0015992)2.91848579
119positive regulation of T cell apoptotic process (GO:0070234)2.89199546
120hydrogen transport (GO:0006818)2.85477495
121positive regulation of fatty acid transport (GO:2000193)2.84628154
122positive regulation of defense response to virus by host (GO:0002230)2.81621163
123positive regulation of icosanoid secretion (GO:0032305)2.78953655
124ubiquinone metabolic process (GO:0006743)2.78661184
125L-fucose catabolic process (GO:0042355)2.78313936
126fucose catabolic process (GO:0019317)2.78313936
127L-fucose metabolic process (GO:0042354)2.78313936
128tryptophan catabolic process (GO:0006569)2.76083755
129indole-containing compound catabolic process (GO:0042436)2.76083755
130indolalkylamine catabolic process (GO:0046218)2.76083755
131protein neddylation (GO:0045116)2.72816793
132energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.70970883
133ATP hydrolysis coupled proton transport (GO:0015991)2.70970883
134protein-cofactor linkage (GO:0018065)2.70143821
135purine deoxyribonucleotide metabolic process (GO:0009151)2.68967270
136kynurenine metabolic process (GO:0070189)2.67773609
137indolalkylamine metabolic process (GO:0006586)2.65436423
138preassembly of GPI anchor in ER membrane (GO:0016254)2.65313476
139phosphatidylglycerol biosynthetic process (GO:0006655)2.61262605
140positive regulation of lymphocyte apoptotic process (GO:0070230)2.60274389
141sequestering of actin monomers (GO:0042989)2.59744956
1422-deoxyribonucleotide metabolic process (GO:0009394)2.59126942
143cellular biogenic amine catabolic process (GO:0042402)2.58873300
144amine catabolic process (GO:0009310)2.58873300
145tRNA processing (GO:0008033)2.57600736
146opioid receptor signaling pathway (GO:0038003)2.55451037
147organelle membrane fusion (GO:0090174)2.55179196
148negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.54587297
149cellular response to exogenous dsRNA (GO:0071360)2.53129288
150intracellular protein transmembrane import (GO:0044743)2.52989816

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.98373339
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.87990657
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.26222831
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.96683261
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.93883513
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.85557224
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.83014536
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.64149805
9* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.63317805
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.56101667
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.43272705
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.31736340
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.03525361
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.93310804
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.75058595
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65842039
17RBPJ_22232070_ChIP-Seq_NCS_Mouse2.56958377
18VDR_23849224_ChIP-Seq_CD4+_Human2.55538104
19XRN2_22483619_ChIP-Seq_HELA_Human2.55259227
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.47054260
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.44130070
22* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38640620
23E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.37816560
24FOXP3_21729870_ChIP-Seq_TREG_Human2.36593674
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.34597771
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.33895022
27FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.31042465
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.29849928
29IRF8_22096565_ChIP-ChIP_GC-B_Human2.25284503
30ZNF274_21170338_ChIP-Seq_K562_Hela2.22702253
31BCL6_27268052_Chip-Seq_Bcells_Human2.20579050
32* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.20488827
33DCP1A_22483619_ChIP-Seq_HELA_Human2.19822990
34SRF_21415370_ChIP-Seq_HL-1_Mouse2.13858645
35YY1_21170310_ChIP-Seq_MESCs_Mouse2.11536513
36E2F7_22180533_ChIP-Seq_HELA_Human2.08943095
37TTF2_22483619_ChIP-Seq_HELA_Human2.05035779
38GABP_19822575_ChIP-Seq_HepG2_Human1.91795247
39* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.91431111
40CIITA_25753668_ChIP-Seq_RAJI_Human1.86944258
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86554484
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.82554749
43PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.80386024
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79394381
45* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.76359956
46P68_20966046_ChIP-Seq_HELA_Human1.75256083
47ELF1_20517297_ChIP-Seq_JURKAT_Human1.74560918
48E2F1_20622854_ChIP-Seq_HELA_Human1.74308705
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.67265473
50* TET1_21451524_ChIP-Seq_MESCs_Mouse1.67018773
51EZH2_22144423_ChIP-Seq_EOC_Human1.66921385
52CTCF_20526341_ChIP-Seq_ESCs_Human1.64402201
53BCOR_27268052_Chip-Seq_Bcells_Human1.62322324
54NOTCH1_21737748_ChIP-Seq_TLL_Human1.61360955
55TAF2_19829295_ChIP-Seq_ESCs_Human1.61230978
56PHF8_20622854_ChIP-Seq_HELA_Human1.59941993
57ERA_21632823_ChIP-Seq_H3396_Human1.59408547
58LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.55103323
59E2F4_17652178_ChIP-ChIP_JURKAT_Human1.54964479
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.54937623
61* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.54092592
62NELFA_20434984_ChIP-Seq_ESCs_Mouse1.52426038
63* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.52021998
64SRY_22984422_ChIP-ChIP_TESTIS_Rat1.50227218
65RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.50139614
66EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.47585186
67P300_27268052_Chip-Seq_Bcells_Human1.46743041
68SCL_19346495_ChIP-Seq_HPC-7_Human1.46238094
69NANOG_20526341_ChIP-Seq_ESCs_Human1.45577594
70MYC_18940864_ChIP-ChIP_HL60_Human1.45552023
71VDR_21846776_ChIP-Seq_THP-1_Human1.45042371
72ELK1_19687146_ChIP-ChIP_HELA_Human1.44707516
73BP1_19119308_ChIP-ChIP_Hs578T_Human1.42506686
74CTCF_26484167_Chip-Seq_Bcells_Mouse1.42214390
75VDR_22108803_ChIP-Seq_LS180_Human1.41670629
76FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.41033277
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.40076843
78ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36085130
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34978512
80SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.34610833
81PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34311251
82POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31298984
83* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.29178870
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.28262580
85CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.26227508
86ELK1_22589737_ChIP-Seq_MCF10A_Human1.26197554
87RAC3_21632823_ChIP-Seq_H3396_Human1.25444428
88SA1_27219007_Chip-Seq_Bcells_Human1.25281848
89* SPI1_23547873_ChIP-Seq_NB4_Human1.24091372
90CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.24023860
91* GATA3_21878914_ChIP-Seq_MCF-7_Human1.22835743
92YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20527918
93CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.20006146
94P53_21459846_ChIP-Seq_SAOS-2_Human1.19511092
95SPI1_20517297_ChIP-Seq_HL60_Human1.19350262
96* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.18201066
97EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.17889561
98TP53_22573176_ChIP-Seq_HFKS_Human1.17362257
99ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.17319377
100MYC_19829295_ChIP-Seq_ESCs_Human1.17085852
101CTCF_27219007_Chip-Seq_Bcells_Human1.15364893
102CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15056497
103VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.14108025
104ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.13286734
105PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.12541283
106BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12518622
107* LXR_22292898_ChIP-Seq_THP-1_Human1.10715302
108OCT4_20526341_ChIP-Seq_ESCs_Human1.09674721
109RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.09047786
110EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.08854645
111ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08469543
112SUZ12_27294783_Chip-Seq_ESCs_Mouse1.08170665
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.06251688
114MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.05940382
115EZH2_27294783_Chip-Seq_ESCs_Mouse1.05579745
116IKZF1_21737484_ChIP-ChIP_HCT116_Human1.04940531
117* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.03467677
118SA1_27219007_Chip-Seq_ERYTHROID_Human1.00960583
119FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99906761
120MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.99010975
121IRF8_21731497_ChIP-ChIP_J774_Mouse0.98710830
122* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.98398727
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98011708
124* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96639577
125KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94879259
126GATA1_22383799_ChIP-Seq_G1ME_Mouse0.93051485
127KDM5A_27292631_Chip-Seq_BREAST_Human0.89834450
128CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.89021287
129IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.88195403
130SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88125637
131E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88078943
132MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.87681934
133LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.87614781
134YY1_22570637_ChIP-Seq_MALME-3M_Human0.87455185
135MYC_22102868_ChIP-Seq_BL_Human0.86322310
136* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.83849041
137TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81278738
138ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.81245540
139* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.80529420
140* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.80149754
141VDR_24763502_ChIP-Seq_THP-1_Human0.79981219
142CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.78886131
143STAT1_20625510_ChIP-Seq_HELA_Human0.78693453
144IRF1_19129219_ChIP-ChIP_H3396_Human0.77379531
145* FOXP1_21924763_ChIP-Seq_HESCs_Human0.75799185
146TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.75339360
147PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.75273581
148PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.74549672
149CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.74326735

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.27956712
2MP0001529_abnormal_vocalization3.92512662
3MP0002653_abnormal_ependyma_morphology3.07892040
4MP0001905_abnormal_dopamine_level2.80842772
5MP0003880_abnormal_central_pattern2.74145505
6MP0005174_abnormal_tail_pigmentation2.66160664
7MP0006036_abnormal_mitochondrial_physio2.46801347
8MP0002396_abnormal_hematopoietic_system2.41177294
9MP0004147_increased_porphyrin_level2.38658517
10MP0002837_dystrophic_cardiac_calcinosis2.34198807
11MP0002736_abnormal_nociception_after2.32206895
12MP0001968_abnormal_touch/_nociception2.26032625
13MP0005409_darkened_coat_color2.11269598
14MP0005423_abnormal_somatic_nervous2.09930594
15MP0006292_abnormal_olfactory_placode2.06993190
16MP0005075_abnormal_melanosome_morpholog2.00872028
17MP0006276_abnormal_autonomic_nervous2.00721002
18MP0003806_abnormal_nucleotide_metabolis1.99145600
19MP0006035_abnormal_mitochondrial_morpho1.98709825
20MP0003646_muscle_fatigue1.94560858
21MP0005645_abnormal_hypothalamus_physiol1.86878039
22MP0008875_abnormal_xenobiotic_pharmacok1.79047842
23MP0005551_abnormal_eye_electrophysiolog1.74995985
24MP0002234_abnormal_pharynx_morphology1.74368599
25MP0009046_muscle_twitch1.72476449
26MP0005671_abnormal_response_to1.69862931
27MP0009764_decreased_sensitivity_to1.63441038
28MP0002638_abnormal_pupillary_reflex1.63091677
29MP0002102_abnormal_ear_morphology1.63076775
30MP0004142_abnormal_muscle_tone1.62150513
31MP0001188_hyperpigmentation1.61230772
32MP0002163_abnormal_gland_morphology1.60613572
33MP0003763_abnormal_thymus_physiology1.55077640
34MP0002095_abnormal_skin_pigmentation1.54942302
35MP0000372_irregular_coat_pigmentation1.54435174
36MP0002876_abnormal_thyroid_physiology1.51961541
37MP0001986_abnormal_taste_sensitivity1.50673502
38MP0000465_gastrointestinal_hemorrhage1.46942905
39MP0005083_abnormal_biliary_tract1.45121543
40MP0004957_abnormal_blastocyst_morpholog1.39965390
41MP0004145_abnormal_muscle_electrophysio1.38979346
42MP0001984_abnormal_olfaction1.33978348
43MP0005646_abnormal_pituitary_gland1.33298652
44MP0003195_calcinosis1.32731653
45MP0000015_abnormal_ear_pigmentation1.31928220
46MP0004133_heterotaxia1.31331596
47MP0000685_abnormal_immune_system1.31250611
48MP0000749_muscle_degeneration1.27982489
49MP0006072_abnormal_retinal_apoptosis1.27725445
50MP0002735_abnormal_chemical_nociception1.26940527
51MP0004742_abnormal_vestibular_system1.26656996
52MP0001835_abnormal_antigen_presentation1.26574674
53MP0003866_abnormal_defecation1.26283516
54MP0003693_abnormal_embryo_hatching1.25579906
55MP0004043_abnormal_pH_regulation1.25491695
56MP0004130_abnormal_muscle_cell1.24878553
57MP0002277_abnormal_respiratory_mucosa1.24206313
58MP0002398_abnormal_bone_marrow1.22272325
59MP0002272_abnormal_nervous_system1.22241721
60MP0000751_myopathy1.22066660
61MP0003011_delayed_dark_adaptation1.21924051
62MP0003787_abnormal_imprinting1.21073453
63MP0001664_abnormal_digestion1.19547143
64MP0003315_abnormal_perineum_morphology1.19310203
65MP0005670_abnormal_white_adipose1.17593945
66MP0003186_abnormal_redox_activity1.17130183
67MP0001501_abnormal_sleep_pattern1.16105733
68MP0009745_abnormal_behavioral_response1.15420143
69MP0005464_abnormal_platelet_physiology1.13642135
70MP0003635_abnormal_synaptic_transmissio1.12859978
71MP0001873_stomach_inflammation1.12123192
72MP0005389_reproductive_system_phenotype1.12063797
73MP0003724_increased_susceptibility_to1.10997297
74MP0000689_abnormal_spleen_morphology1.10944079
75MP0001853_heart_inflammation1.10579553
76MP0009278_abnormal_bone_marrow1.09241490
77MP0002160_abnormal_reproductive_system1.09025500
78MP0001919_abnormal_reproductive_system1.08643652
79MP0001790_abnormal_immune_system1.07329865
80MP0005387_immune_system_phenotype1.07329865
81MP0002067_abnormal_sensory_capabilities1.07293737
82MP0009333_abnormal_splenocyte_physiolog1.06889657
83MP0008569_lethality_at_weaning1.06841371
84MP0003137_abnormal_impulse_conducting1.06703159
85MP0001970_abnormal_pain_threshold1.05703709
86MP0003656_abnormal_erythrocyte_physiolo1.04288251
87MP0002132_abnormal_respiratory_system1.04223379
88MP0002938_white_spotting1.02889774
89MP0001663_abnormal_digestive_system1.02615511
90MP0009785_altered_susceptibility_to1.02613108
91MP0002722_abnormal_immune_system1.02345809
92MP0000490_abnormal_crypts_of1.01884349
93MP0002064_seizures0.99625251
94MP0005386_behavior/neurological_phenoty0.99207774
95MP0004924_abnormal_behavior0.99207774
96MP0002733_abnormal_thermal_nociception0.99155090
97MP0000703_abnormal_thymus_morphology0.97792142
98MP0003786_premature_aging0.97777028
99MP0002420_abnormal_adaptive_immunity0.96964223
100MP0005025_abnormal_response_to0.95852612
101MP0002429_abnormal_blood_cell0.95837054
102MP0005000_abnormal_immune_tolerance0.95719763
103MP0005410_abnormal_fertilization0.94880155
104MP0001764_abnormal_homeostasis0.93813692
105MP0008932_abnormal_embryonic_tissue0.93734337
106MP0002693_abnormal_pancreas_physiology0.93418544
107MP0002734_abnormal_mechanical_nocicepti0.93258856
108MP0005084_abnormal_gallbladder_morpholo0.93104625
109MP0001819_abnormal_immune_cell0.92811407
110MP0005332_abnormal_amino_acid0.92466618
111MP0002572_abnormal_emotion/affect_behav0.92397933
112MP0001800_abnormal_humoral_immune0.91989085
113MP0004036_abnormal_muscle_relaxation0.91665340
114MP0000716_abnormal_immune_system0.90251481
115MP0000358_abnormal_cell_content/0.89943170
116MP0003077_abnormal_cell_cycle0.89837841
117MP0004270_analgesia0.89712806
118MP0000631_abnormal_neuroendocrine_gland0.89356959
119MP0001485_abnormal_pinna_reflex0.88762848
120MP0008872_abnormal_physiological_respon0.88617523
121MP0003136_yellow_coat_color0.87325060
122MP0000750_abnormal_muscle_regeneration0.87248926
123MP0002557_abnormal_social/conspecific_i0.87150213
124MP0001440_abnormal_grooming_behavior0.86881152
125MP0000230_abnormal_systemic_arterial0.86050143
126MP0002184_abnormal_innervation0.86003094
127MP0000049_abnormal_middle_ear0.85755297
128MP0004808_abnormal_hematopoietic_stem0.84573872
129MP0008877_abnormal_DNA_methylation0.84483526
130MP0010094_abnormal_chromosome_stability0.84223134
131MP0002822_catalepsy0.84006349
132MP0008058_abnormal_DNA_repair0.83525604
133MP0005253_abnormal_eye_physiology0.83406965
134MP0002148_abnormal_hypersensitivity_rea0.82658630
135MP0004215_abnormal_myocardial_fiber0.81850048
136MP0002723_abnormal_immune_serum0.80909270
137MP0003123_paternal_imprinting0.80363488
138MP0008469_abnormal_protein_level0.79945820
139MP0003221_abnormal_cardiomyocyte_apopto0.79782255
140MP0002751_abnormal_autonomic_nervous0.79703571
141MP0005381_digestive/alimentary_phenotyp0.79511255
142MP0002138_abnormal_hepatobiliary_system0.78852762
143MP0005448_abnormal_energy_balance0.77781068
144MP0005636_abnormal_mineral_homeostasis0.77582180
145MP0003718_maternal_effect0.77482588
146MP0005379_endocrine/exocrine_gland_phen0.77367722
147MP0003567_abnormal_fetal_cardiomyocyte0.77205405
148MP0006054_spinal_hemorrhage0.76033269
149MP0002452_abnormal_antigen_presenting0.75733201

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.30815669
2Hepatocellular necrosis (HP:0001404)5.87983160
3Abnormal number of erythroid precursors (HP:0012131)5.82414649
4Mitochondrial inheritance (HP:0001427)5.79889390
5Acute necrotizing encephalopathy (HP:0006965)5.67123426
6Abnormal mitochondria in muscle tissue (HP:0008316)5.30302387
7Increased CSF lactate (HP:0002490)4.93742351
8Hepatic necrosis (HP:0002605)4.91610248
9Increased hepatocellular lipid droplets (HP:0006565)4.80492060
10Reticulocytopenia (HP:0001896)4.73689945
11Acute encephalopathy (HP:0006846)4.65927746
12Progressive macrocephaly (HP:0004481)4.63463690
13Decreased activity of mitochondrial respiratory chain (HP:0008972)4.58435742
14Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.58435742
15Lipid accumulation in hepatocytes (HP:0006561)4.44560501
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.43566123
17Macrocytic anemia (HP:0001972)4.36637013
183-Methylglutaconic aciduria (HP:0003535)4.14604468
19Increased serum pyruvate (HP:0003542)4.07260857
20Abnormality of glycolysis (HP:0004366)4.07260857
21Increased intramyocellular lipid droplets (HP:0012240)4.02387638
22Pallor (HP:0000980)3.86034921
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.85076379
24Increased serum lactate (HP:0002151)3.72119307
25Renal Fanconi syndrome (HP:0001994)3.71479760
26Lactic acidosis (HP:0003128)3.63192853
27Increased muscle lipid content (HP:0009058)3.62083998
28Exercise intolerance (HP:0003546)3.51113396
29Pancreatic cysts (HP:0001737)3.47035136
30Respiratory failure (HP:0002878)3.36916727
31Molar tooth sign on MRI (HP:0002419)3.33160009
32Abnormality of midbrain morphology (HP:0002418)3.33160009
33Congenital stationary night blindness (HP:0007642)3.31290381
34Exertional dyspnea (HP:0002875)3.26704660
35Aplastic anemia (HP:0001915)3.24439410
36Decreased electroretinogram (ERG) amplitude (HP:0000654)3.22879068
37Aplasia/Hypoplasia of the sacrum (HP:0008517)3.17392920
38Cerebral edema (HP:0002181)3.00991134
39Pancreatic fibrosis (HP:0100732)2.98490100
40Microvesicular hepatic steatosis (HP:0001414)2.95156142
41Optic disc pallor (HP:0000543)2.94639520
42Respiratory difficulties (HP:0002880)2.93163495
43Ragged-red muscle fibers (HP:0003200)2.83734681
44Emotional lability (HP:0000712)2.81208913
45Thrombocytosis (HP:0001894)2.77891820
46True hermaphroditism (HP:0010459)2.71262288
47Severe visual impairment (HP:0001141)2.64375614
48Abnormality of the heme biosynthetic pathway (HP:0010472)2.61907707
49Nephronophthisis (HP:0000090)2.61572468
50Absent rod-and cone-mediated responses on ERG (HP:0007688)2.57644519
51Microretrognathia (HP:0000308)2.56330297
52Increased neuronal autofluorescent lipopigment (HP:0002074)2.47535478
53CNS demyelination (HP:0007305)2.46238179
54Hypothermia (HP:0002045)2.43029596
55Progressive microcephaly (HP:0000253)2.39904749
56Sclerocornea (HP:0000647)2.38302901
57Concave nail (HP:0001598)2.34553785
58IgM deficiency (HP:0002850)2.29272367
59Attenuation of retinal blood vessels (HP:0007843)2.27670035
60Cerebral hypomyelination (HP:0006808)2.26820809
61Severe muscular hypotonia (HP:0006829)2.22992482
62Type I transferrin isoform profile (HP:0003642)2.22893565
63Abolished electroretinogram (ERG) (HP:0000550)2.22770194
64Petechiae (HP:0000967)2.22367128
65Leukodystrophy (HP:0002415)2.21372956
66Retinal dysplasia (HP:0007973)2.20171798
67Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.19405397
6811 pairs of ribs (HP:0000878)2.18806570
69Neuroendocrine neoplasm (HP:0100634)2.18307113
70Type II lissencephaly (HP:0007260)2.17077048
71Mesangial abnormality (HP:0001966)2.15269910
72Medial flaring of the eyebrow (HP:0010747)2.09462035
73Oral leukoplakia (HP:0002745)2.07940206
74Elevated erythrocyte sedimentation rate (HP:0003565)2.06918074
75Abnormality of renal resorption (HP:0011038)2.06718330
76Hypoplasia of the pons (HP:0012110)2.05216405
77Pendular nystagmus (HP:0012043)1.99011651
78Abnormality of the renal medulla (HP:0100957)1.96281757
79Delusions (HP:0000746)1.95725069
80Increased cerebral lipofuscin (HP:0011813)1.95567159
81Panhypogammaglobulinemia (HP:0003139)1.94974501
82Muscle fiber atrophy (HP:0100295)1.94629562
83Hyperphosphaturia (HP:0003109)1.92032718
84Ketosis (HP:0001946)1.91425375
85Cystic liver disease (HP:0006706)1.90109612
86Progressive muscle weakness (HP:0003323)1.87993236
87Abnormal drinking behavior (HP:0030082)1.87407990
88Polydipsia (HP:0001959)1.87407990
89Decreased central vision (HP:0007663)1.87138140
90Abnormality of the pons (HP:0007361)1.86838115
91IgG deficiency (HP:0004315)1.85903196
92Dry hair (HP:0011359)1.85314563
93Pancytopenia (HP:0001876)1.85080374
94Dicarboxylic aciduria (HP:0003215)1.83379061
95Abnormality of dicarboxylic acid metabolism (HP:0010995)1.83379061
96Methylmalonic aciduria (HP:0012120)1.83143557
97Colon cancer (HP:0003003)1.83052623
98Gliosis (HP:0002171)1.82775397
99Abnormal rod and cone electroretinograms (HP:0008323)1.82735532
100Absent/shortened dynein arms (HP:0200106)1.81662521
101Dynein arm defect of respiratory motile cilia (HP:0012255)1.81662521
102Cerebral palsy (HP:0100021)1.80717730
103Congenital, generalized hypertrichosis (HP:0004540)1.79486734
104Polyphagia (HP:0002591)1.79402837
105Polyuria (HP:0000103)1.79102208
106Opisthotonus (HP:0002179)1.78515130
107Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.77622307
108Clumsiness (HP:0002312)1.76598907
109Unsteady gait (HP:0002317)1.75379499
110Absent thumb (HP:0009777)1.75311114
111Agitation (HP:0000713)1.74751709
112Glycosuria (HP:0003076)1.73174301
113Abnormality of urine glucose concentration (HP:0011016)1.73174301
114Aplasia/Hypoplasia of the patella (HP:0006498)1.73021766
115Agammaglobulinemia (HP:0004432)1.72146790
116Type 2 muscle fiber atrophy (HP:0003554)1.68175139
117Limb dystonia (HP:0002451)1.67845234
118Visual hallucinations (HP:0002367)1.67731276
119Ketoacidosis (HP:0001993)1.67381298
120Generalized aminoaciduria (HP:0002909)1.67299347
121Abnormal pupillary function (HP:0007686)1.66294558
122Myotonia (HP:0002486)1.65849518
123Abnormality of alanine metabolism (HP:0010916)1.65674013
124Hyperalaninemia (HP:0003348)1.65674013
125Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.65674013
126Pheochromocytoma (HP:0002666)1.63769360
127Multiple enchondromatosis (HP:0005701)1.59921103
128Abnormal protein glycosylation (HP:0012346)1.59662783
129Abnormal glycosylation (HP:0012345)1.59662783
130Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.59662783
131Abnormal protein N-linked glycosylation (HP:0012347)1.59662783
132Depressed nasal ridge (HP:0000457)1.58932359
133Rough bone trabeculation (HP:0100670)1.58077709
134Hyperventilation (HP:0002883)1.56775288
135Prolonged bleeding time (HP:0003010)1.55781370
136Rimmed vacuoles (HP:0003805)1.54759308
137Muscle hypertrophy of the lower extremities (HP:0008968)1.54417430
138Myokymia (HP:0002411)1.53851635
139X-linked dominant inheritance (HP:0001423)1.51508125
140Cerebellar dysplasia (HP:0007033)1.51199277
141Migraine (HP:0002076)1.49592479
142Increased serum ferritin (HP:0003281)1.48923670
143Purpura (HP:0000979)1.48071796
144Lethargy (HP:0001254)1.48068287
145Amniotic constriction ring (HP:0009775)1.47136131
146Abnormality of placental membranes (HP:0011409)1.47136131
147Lissencephaly (HP:0001339)1.46304584
148Neoplasm of the peripheral nervous system (HP:0100007)1.45200324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.47123111
2VRK24.19532129
3STK163.91458933
4MAP3K123.66864145
5TLK13.23106763
6CDK192.69621377
7NME12.66594612
8ZAK2.46523000
9WEE12.35286039
10FRK2.28575950
11MAP4K12.20764997
12MAP4K22.15401778
13VRK12.07834556
14TAOK32.00908319
15BUB11.99348178
16PIM21.95052354
17ARAF1.85115906
18NUAK11.80944118
19GRK11.78305095
20FLT31.72135279
21INSRR1.70284371
22EIF2AK11.65189841
23MYLK1.61027744
24BCKDK1.60243672
25KIT1.57923251
26GRK61.53910926
27TNIK1.53190130
28DYRK31.52234249
29CCNB11.50989149
30ACVR1B1.48708645
31IKBKB1.46309341
32BTK1.39579276
33WNK41.39296604
34PINK11.37535089
35BMPR1B1.35542201
36MAPKAPK51.33440311
37SYK1.31335122
38SRPK11.30277010
39DYRK21.28904896
40MUSK1.28771294
41CASK1.27757933
42DAPK21.16042038
43MAPK131.16021513
44SCYL21.15375910
45BLK1.14754401
46ADRBK21.12228401
47ILK1.12116143
48UHMK11.08233602
49CSF1R1.07821703
50KDR1.06912751
51TEC1.04035962
52CSNK1G31.00824710
53DAPK11.00780907
54CDK81.00091420
55TESK20.99248195
56FES0.97774783
57MAP3K110.96624353
58PNCK0.96284561
59MAPKAPK30.94118481
60GRK70.93106078
61ZAP700.92736992
62MARK10.89824854
63CLK10.85997002
64PKN10.85318239
65IRAK40.85094588
66MAP2K30.84619394
67TXK0.83338304
68MAP2K60.83098431
69BRAF0.82001936
70PHKG10.79689224
71PHKG20.79689224
72TESK10.79240330
73CSNK1A1L0.77061654
74MAP2K70.76152238
75TGFBR10.75812255
76PIK3CG0.74511956
77TBK10.73570643
78ERN10.72051907
79LMTK20.70897346
80WNK30.70856218
81MAPK40.70742966
82EIF2AK30.70276948
83OXSR10.69538270
84ADRBK10.69180417
85TSSK60.68863897
86PRKCQ0.68634328
87MINK10.68113996
88LYN0.66675228
89AURKA0.66426034
90DAPK30.65714242
91CAMK10.65682134
92TAF10.64946348
93MAP2K20.64381652
94MKNK10.63627717
95IKBKE0.61161469
96CHEK20.59878924
97CAMK2B0.58847741
98CAMKK20.58294617
99TNK20.57790417
100NTRK20.57349569
101PRKCG0.56203455
102RAF10.55918288
103PIK3CA0.54671415
104MATK0.54329884
105LIMK10.54102322
106CSNK2A20.53680434
107CSNK2A10.53115854
108ABL20.50849257
109STK110.48769703
110MAPK120.47956971
111RIPK40.47521386
112LRRK20.47505851
113SIK20.47288749
114MAP2K40.47109686
115CDC70.45462230
116RPS6KB20.44948324
117GRK50.44322512
118PTK2B0.44286698
119CSNK1G20.43787002
120LCK0.43203964
121CSNK1A10.42633746
122MKNK20.42588395
123CSNK1G10.42273701
124PRKCI0.42101976
125MAP3K40.41948598
126CHUK0.40860396
127MAP3K60.40813149
128PIM10.38960586
129PASK0.38919488
130RPS6KA50.38137775
131TIE10.37993140
132PRKACA0.37826058
133CDK11A0.36429482
134MARK30.35804102
135EEF2K0.35543147
136CAMKK10.35431395
137MAPK150.35263460
138RPS6KA60.35180893
139HIPK20.34682572
140PAK40.34071581
141CAMK2G0.34035597
142PRKD20.33571639

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.88921679
2Oxidative phosphorylation_Homo sapiens_hsa001904.69682291
3Parkinsons disease_Homo sapiens_hsa050124.48094792
4Proteasome_Homo sapiens_hsa030503.84972646
5DNA replication_Homo sapiens_hsa030303.29521650
6Alzheimers disease_Homo sapiens_hsa050103.24879926
7RNA polymerase_Homo sapiens_hsa030203.06953002
8Huntingtons disease_Homo sapiens_hsa050163.03178188
9Protein export_Homo sapiens_hsa030602.65520730
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.61916870
11Mismatch repair_Homo sapiens_hsa034302.49304918
12Spliceosome_Homo sapiens_hsa030402.46917377
13Pyrimidine metabolism_Homo sapiens_hsa002402.38595274
14Base excision repair_Homo sapiens_hsa034102.10708403
15Intestinal immune network for IgA production_Homo sapiens_hsa046722.09257282
16Cardiac muscle contraction_Homo sapiens_hsa042601.98404329
17Nucleotide excision repair_Homo sapiens_hsa034201.93175903
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.91337225
19Asthma_Homo sapiens_hsa053101.82937859
20Homologous recombination_Homo sapiens_hsa034401.82843327
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.73362613
22Linoleic acid metabolism_Homo sapiens_hsa005911.68566447
23Allograft rejection_Homo sapiens_hsa053301.48760190
24Graft-versus-host disease_Homo sapiens_hsa053321.43180533
25Purine metabolism_Homo sapiens_hsa002301.43067755
26Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.40131670
27Autoimmune thyroid disease_Homo sapiens_hsa053201.36124236
28Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27747512
29Nitrogen metabolism_Homo sapiens_hsa009101.25368902
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20637492
31Sulfur relay system_Homo sapiens_hsa041221.20413403
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20285623
33Folate biosynthesis_Homo sapiens_hsa007901.17514475
34Butanoate metabolism_Homo sapiens_hsa006501.17186315
35RNA degradation_Homo sapiens_hsa030181.13471893
36Rheumatoid arthritis_Homo sapiens_hsa053231.12519243
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.11867193
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11682327
39Ether lipid metabolism_Homo sapiens_hsa005651.10156272
40Tryptophan metabolism_Homo sapiens_hsa003801.08885911
41Type I diabetes mellitus_Homo sapiens_hsa049401.08175601
42Peroxisome_Homo sapiens_hsa041461.03958441
43Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.03478256
44RNA transport_Homo sapiens_hsa030131.00673912
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00342376
46Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.97094270
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.91320007
48Basal transcription factors_Homo sapiens_hsa030220.91041453
49Pentose phosphate pathway_Homo sapiens_hsa000300.83739064
50Primary immunodeficiency_Homo sapiens_hsa053400.83537541
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83079978
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.82036418
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.78998713
54N-Glycan biosynthesis_Homo sapiens_hsa005100.75352154
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.73514961
56Nicotine addiction_Homo sapiens_hsa050330.70753596
57Caffeine metabolism_Homo sapiens_hsa002320.69147701
58Metabolic pathways_Homo sapiens_hsa011000.68648791
59Fatty acid elongation_Homo sapiens_hsa000620.66848236
60Antigen processing and presentation_Homo sapiens_hsa046120.66285198
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66199967
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.64879362
63Alcoholism_Homo sapiens_hsa050340.63019644
64Phototransduction_Homo sapiens_hsa047440.62324713
65Non-homologous end-joining_Homo sapiens_hsa034500.60151218
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.60011114
67Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.59846418
68Fanconi anemia pathway_Homo sapiens_hsa034600.59733593
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59294309
70Selenocompound metabolism_Homo sapiens_hsa004500.59082394
71Cell cycle_Homo sapiens_hsa041100.58797358
72Other glycan degradation_Homo sapiens_hsa005110.56649523
73Serotonergic synapse_Homo sapiens_hsa047260.55574522
74Epstein-Barr virus infection_Homo sapiens_hsa051690.55215176
75Olfactory transduction_Homo sapiens_hsa047400.54625608
76Chemical carcinogenesis_Homo sapiens_hsa052040.52862560
77Lysosome_Homo sapiens_hsa041420.52538280
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.52259751
79Carbon metabolism_Homo sapiens_hsa012000.51452033
80Systemic lupus erythematosus_Homo sapiens_hsa053220.48987727
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48149911
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47069041
83Staphylococcus aureus infection_Homo sapiens_hsa051500.46996377
84Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.46914981
85Cysteine and methionine metabolism_Homo sapiens_hsa002700.46406376
86One carbon pool by folate_Homo sapiens_hsa006700.46175474
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43583632
88Fat digestion and absorption_Homo sapiens_hsa049750.43356110
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42762913
90B cell receptor signaling pathway_Homo sapiens_hsa046620.41654553
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41014717
92Ovarian steroidogenesis_Homo sapiens_hsa049130.39907009
93Pyruvate metabolism_Homo sapiens_hsa006200.39222326
94Vibrio cholerae infection_Homo sapiens_hsa051100.39152054
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38701421
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.37647459
97Glycerolipid metabolism_Homo sapiens_hsa005610.37338861
98Glutathione metabolism_Homo sapiens_hsa004800.36758721
99Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.36605961
100Taste transduction_Homo sapiens_hsa047420.36584266
101Hematopoietic cell lineage_Homo sapiens_hsa046400.35374859
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.35134690
103Glycerophospholipid metabolism_Homo sapiens_hsa005640.34359882
104Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34321863
105Dopaminergic synapse_Homo sapiens_hsa047280.33911190
106Calcium signaling pathway_Homo sapiens_hsa040200.29275440
107Drug metabolism - other enzymes_Homo sapiens_hsa009830.28831241
108Salivary secretion_Homo sapiens_hsa049700.28773087
109mRNA surveillance pathway_Homo sapiens_hsa030150.27492999
110Glycosaminoglycan degradation_Homo sapiens_hsa005310.27209926
111Tyrosine metabolism_Homo sapiens_hsa003500.26734931
112Biosynthesis of amino acids_Homo sapiens_hsa012300.26734211
113Arachidonic acid metabolism_Homo sapiens_hsa005900.26616202
114NF-kappa B signaling pathway_Homo sapiens_hsa040640.26191920
115Regulation of autophagy_Homo sapiens_hsa041400.24406423
116Propanoate metabolism_Homo sapiens_hsa006400.24040835
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.21084899
118Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.20178755
119Morphine addiction_Homo sapiens_hsa050320.19586406
120Oocyte meiosis_Homo sapiens_hsa041140.19089233
121Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.18484687
122Shigellosis_Homo sapiens_hsa051310.17278281
123Synaptic vesicle cycle_Homo sapiens_hsa047210.16893020
124Long-term depression_Homo sapiens_hsa047300.13778479
125Platelet activation_Homo sapiens_hsa046110.12251562
126GABAergic synapse_Homo sapiens_hsa047270.12045974
127Glutamatergic synapse_Homo sapiens_hsa047240.11685615
128Sphingolipid metabolism_Homo sapiens_hsa006000.11466106
129Circadian entrainment_Homo sapiens_hsa047130.11001251
130Amphetamine addiction_Homo sapiens_hsa050310.10863471
131Cholinergic synapse_Homo sapiens_hsa047250.09556012
132Cocaine addiction_Homo sapiens_hsa050300.09162603
133Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08782250
134Collecting duct acid secretion_Homo sapiens_hsa049660.08516083
135Sulfur metabolism_Homo sapiens_hsa009200.07417312
136Long-term potentiation_Homo sapiens_hsa047200.06447057
1372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.05703349
138Sphingolipid signaling pathway_Homo sapiens_hsa040710.05570738
139Acute myeloid leukemia_Homo sapiens_hsa052210.05475822
140Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.03841573
141Fructose and mannose metabolism_Homo sapiens_hsa000510.03830341

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