TRAM1L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.43081899
2vocalization behavior (GO:0071625)5.14174169
3synaptic vesicle exocytosis (GO:0016079)4.97915235
4regulation of short-term neuronal synaptic plasticity (GO:0048172)4.83529883
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.70380690
6protein localization to synapse (GO:0035418)4.54206545
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.28171652
8regulation of glutamate receptor signaling pathway (GO:1900449)4.27269755
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.26205548
10regulation of synaptic vesicle exocytosis (GO:2000300)4.23512147
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.07708223
12neuron recognition (GO:0008038)4.06967838
13synaptic vesicle maturation (GO:0016188)4.04191025
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.00350904
15gamma-aminobutyric acid signaling pathway (GO:0007214)3.99128278
16presynaptic membrane assembly (GO:0097105)3.97291678
17glutamate secretion (GO:0014047)3.95694221
18neuronal action potential propagation (GO:0019227)3.85414529
19glutamate receptor signaling pathway (GO:0007215)3.84232452
20regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.80527337
21axonal fasciculation (GO:0007413)3.74468620
22neuron-neuron synaptic transmission (GO:0007270)3.74000700
23postsynaptic membrane organization (GO:0001941)3.73738610
24negative regulation of synaptic transmission, GABAergic (GO:0032229)3.72470698
25locomotory exploration behavior (GO:0035641)3.70212841
26presynaptic membrane organization (GO:0097090)3.68809659
27regulation of synaptic vesicle transport (GO:1902803)3.68596902
28transmission of nerve impulse (GO:0019226)3.64670762
29neurotransmitter secretion (GO:0007269)3.64442842
30synaptic transmission, glutamatergic (GO:0035249)3.64222748
31neurotransmitter-gated ion channel clustering (GO:0072578)3.62214677
32nucleobase catabolic process (GO:0046113)3.53483022
33response to pheromone (GO:0019236)3.50035096
34positive regulation of synapse assembly (GO:0051965)3.49926168
35exploration behavior (GO:0035640)3.47028096
36retinal ganglion cell axon guidance (GO:0031290)3.40192654
37G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.39686019
38protein localization to cilium (GO:0061512)3.35965841
39regulation of synapse structural plasticity (GO:0051823)3.35347085
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.33972200
41regulation of hexokinase activity (GO:1903299)3.33886812
42regulation of glucokinase activity (GO:0033131)3.33886812
43positive regulation of mitochondrial fission (GO:0090141)3.31232763
44synaptic vesicle docking involved in exocytosis (GO:0016081)3.29231250
45negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.27443965
46response to histamine (GO:0034776)3.26159212
47regulation of feeding behavior (GO:0060259)3.25268485
48startle response (GO:0001964)3.23140223
49layer formation in cerebral cortex (GO:0021819)3.22563365
50cell migration in hindbrain (GO:0021535)3.21481211
51regulation of neuronal synaptic plasticity (GO:0048168)3.20066525
52neurotransmitter transport (GO:0006836)3.19404128
53synaptic vesicle endocytosis (GO:0048488)3.17274422
54regulation of synaptic transmission, glutamatergic (GO:0051966)3.17250247
55negative regulation of axon guidance (GO:1902668)3.16767935
56synapse assembly (GO:0007416)3.15848383
57positive regulation of synaptic transmission, GABAergic (GO:0032230)3.15322827
58dendritic spine morphogenesis (GO:0060997)3.14854391
59long-term synaptic potentiation (GO:0060291)3.14053884
60positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.13645861
61striatum development (GO:0021756)3.12926995
62somite development (GO:0061053)3.12301561
63regulation of glutamate secretion (GO:0014048)3.10477802
64regulation of excitatory postsynaptic membrane potential (GO:0060079)3.10182016
65membrane hyperpolarization (GO:0060081)3.08893794
66regulation of vesicle fusion (GO:0031338)3.06458075
67regulation of postsynaptic membrane potential (GO:0060078)3.05850576
68regulation of long-term neuronal synaptic plasticity (GO:0048169)3.05493678
69positive regulation of synapse maturation (GO:0090129)3.04569757
70response to auditory stimulus (GO:0010996)3.04244262
71positive regulation of membrane potential (GO:0045838)3.01910146
72innervation (GO:0060384)3.01494829
73dendrite morphogenesis (GO:0048813)3.01307451
74auditory behavior (GO:0031223)3.01164783
75establishment of mitochondrion localization (GO:0051654)3.00097368
76intraciliary transport (GO:0042073)3.00064800
77regulation of neurotransmitter secretion (GO:0046928)2.99639367
78regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.98854063
79proline transport (GO:0015824)2.93273514
80regulation of synapse assembly (GO:0051963)2.92958489
81cerebellar Purkinje cell differentiation (GO:0021702)2.90067419
82gamma-aminobutyric acid transport (GO:0015812)2.89147065
83long-term memory (GO:0007616)2.89108262
84regulation of neurotransmitter levels (GO:0001505)2.88532776
85negative regulation of neurotransmitter transport (GO:0051589)2.87686093
86righting reflex (GO:0060013)2.86703672
87regulation of neurotransmitter transport (GO:0051588)2.86173572
88positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.86138728
89nonmotile primary cilium assembly (GO:0035058)2.86090968
90regulation of synaptic transmission, GABAergic (GO:0032228)2.85944008
91behavioral fear response (GO:0001662)2.85486134
92behavioral defense response (GO:0002209)2.85486134
93energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.85058005
94ATP hydrolysis coupled proton transport (GO:0015991)2.85058005
95positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.84407214
96negative regulation of DNA recombination (GO:0045910)2.83157583
97learning (GO:0007612)2.83033774
98cellular potassium ion homeostasis (GO:0030007)2.82924243
99membrane depolarization during action potential (GO:0086010)2.82781793
100synaptic transmission (GO:0007268)2.82571896
101negative regulation of microtubule polymerization (GO:0031115)2.81606553
102mating behavior (GO:0007617)2.81507772
103pyrimidine nucleobase catabolic process (GO:0006208)2.81189991
104adult walking behavior (GO:0007628)2.81158908
105membrane depolarization (GO:0051899)2.81125708
106neuromuscular process controlling posture (GO:0050884)2.80537967
107transferrin transport (GO:0033572)2.79691076
108establishment of synaptic vesicle localization (GO:0097480)2.79545111
109synaptic vesicle transport (GO:0048489)2.79545111
110dendrite development (GO:0016358)2.78601993
111synapse organization (GO:0050808)2.76303716
112cilium morphogenesis (GO:0060271)2.75708899
113peptidyl-cysteine modification (GO:0018198)2.75547474
114fear response (GO:0042596)2.75514966
115L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.74291913
116hindbrain development (GO:0030902)2.73587037
117mechanosensory behavior (GO:0007638)2.73042310
118limb bud formation (GO:0060174)2.72988602
119vascular smooth muscle contraction (GO:0014829)2.72562195
120protein-cofactor linkage (GO:0018065)2.69893813
121DNA integration (GO:0015074)2.67068408
122calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.66293585
123regulation of cilium movement (GO:0003352)2.63661513
124regulation of development, heterochronic (GO:0040034)2.63471349
125otic vesicle formation (GO:0030916)2.60817700
126response to dietary excess (GO:0002021)2.57187764
127regulation of timing of cell differentiation (GO:0048505)2.56481330
128glycerophospholipid catabolic process (GO:0046475)2.54376444
129positive regulation of oligodendrocyte differentiation (GO:0048714)2.53453625
130neuronal action potential (GO:0019228)2.52867082
131negative regulation of axon extension (GO:0030517)2.51909407
132neuron projection extension involved in neuron projection guidance (GO:1902284)2.48977788
133axon extension involved in axon guidance (GO:0048846)2.48977788
134organelle disassembly (GO:1903008)2.48566531
135positive regulation of guanylate cyclase activity (GO:0031284)2.46218511
136short-term memory (GO:0007614)2.45272913
137cornea development in camera-type eye (GO:0061303)2.43099498
138retinal cone cell development (GO:0046549)2.42792829
139axoneme assembly (GO:0035082)2.42687393
140cellular response to leptin stimulus (GO:0044320)2.40598823
141negative chemotaxis (GO:0050919)2.39856882
142coenzyme catabolic process (GO:0009109)2.39793104
143establishment of vesicle localization (GO:0051650)2.39671512
144ribonucleoprotein complex disassembly (GO:0032988)2.38847747
145inner ear receptor stereocilium organization (GO:0060122)2.37453893
146establishment of melanosome localization (GO:0032401)2.37039903
147photoreceptor cell development (GO:0042461)2.35807524
148fatty acid elongation (GO:0030497)2.35385443
149cilium assembly (GO:0042384)2.35109585
150tachykinin receptor signaling pathway (GO:0007217)2.34566628
151melanosome transport (GO:0032402)2.34537491
152GPI anchor metabolic process (GO:0006505)2.33322551
153glycosphingolipid biosynthetic process (GO:0006688)2.33145843
154cilium organization (GO:0044782)2.30154561
155preassembly of GPI anchor in ER membrane (GO:0016254)2.29720382
156positive regulation of amino acid transport (GO:0051957)2.29073487
157neural tube formation (GO:0001841)2.28635620
158C-terminal protein lipidation (GO:0006501)2.27989619
159L-methionine salvage (GO:0071267)2.27114417
160L-methionine biosynthetic process (GO:0071265)2.27114417
161amino acid salvage (GO:0043102)2.27114417
162establishment of pigment granule localization (GO:0051905)2.27016160
163axon extension (GO:0048675)2.26084393
164cerebral cortex radially oriented cell migration (GO:0021799)2.25357944

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.83279598
2GBX2_23144817_ChIP-Seq_PC3_Human4.09079113
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.07532219
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00377616
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.93289752
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.72101389
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.63079136
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.58646549
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57761272
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.56463005
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.56463005
12TAF15_26573619_Chip-Seq_HEK293_Human2.51398262
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.47843384
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45914141
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.44099748
16REST_21632747_ChIP-Seq_MESCs_Mouse2.42946505
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.38753075
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.29819382
19* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29527426
20CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.26382630
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.17542914
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.17243394
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.15203526
24ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08364979
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.07383008
26CTBP1_25329375_ChIP-Seq_LNCAP_Human2.01046497
27* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.98705420
28REST_18959480_ChIP-ChIP_MESCs_Mouse1.95709664
29AR_21572438_ChIP-Seq_LNCaP_Human1.95083627
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.86826226
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.84340195
32DROSHA_22980978_ChIP-Seq_HELA_Human1.82207942
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.80903548
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.79777062
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.77520932
36IGF1R_20145208_ChIP-Seq_DFB_Human1.76928180
37P300_19829295_ChIP-Seq_ESCs_Human1.76219066
38RARB_27405468_Chip-Seq_BRAIN_Mouse1.75712302
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74994427
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73216822
41RBPJ_22232070_ChIP-Seq_NCS_Mouse1.70562772
42SMAD4_21799915_ChIP-Seq_A2780_Human1.67117485
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65657414
44RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.65175135
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.63572448
46E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.62964686
47RNF2_27304074_Chip-Seq_NSC_Mouse1.62484526
48* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59639634
49ZNF274_21170338_ChIP-Seq_K562_Hela1.57384907
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52625573
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51345613
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50730005
53CBP_20019798_ChIP-Seq_JUKART_Human1.50722673
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50722673
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49676401
56FUS_26573619_Chip-Seq_HEK293_Human1.49356942
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47850444
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47758132
59SMAD3_21741376_ChIP-Seq_EPCs_Human1.45697968
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40553964
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.39918975
62VDR_22108803_ChIP-Seq_LS180_Human1.36582427
63ER_23166858_ChIP-Seq_MCF-7_Human1.36140884
64AR_25329375_ChIP-Seq_VCAP_Human1.33505411
65KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.33377572
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.30545239
67GABP_17652178_ChIP-ChIP_JURKAT_Human1.26086600
68P53_22387025_ChIP-Seq_ESCs_Mouse1.22719379
69NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22461197
70IRF1_19129219_ChIP-ChIP_H3396_Human1.22357560
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22111267
72HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21919436
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.21473931
74* SOX2_21211035_ChIP-Seq_LN229_Gbm1.21353787
75EZH2_27294783_Chip-Seq_NPCs_Mouse1.20960710
76RING1B_27294783_Chip-Seq_ESCs_Mouse1.20916225
77SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19952780
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19941367
79RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.19748626
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19042057
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17874567
82STAT3_23295773_ChIP-Seq_U87_Human1.17839338
83BCAT_22108803_ChIP-Seq_LS180_Human1.15909505
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15844112
85TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15405230
86TP53_22573176_ChIP-Seq_HFKS_Human1.15291185
87FLI1_21867929_ChIP-Seq_TH2_Mouse1.14413746
88KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14023574
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12188134
90CDX2_19796622_ChIP-Seq_MESCs_Mouse1.11612017
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11218093
92* SOX2_16153702_ChIP-ChIP_HESCs_Human1.11191935
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.10193599
94* TAL1_26923725_Chip-Seq_HPCs_Mouse1.09804386
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09708934
96MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09574850
97* RUNX2_22187159_ChIP-Seq_PCA_Human1.09141197
98TCF4_22108803_ChIP-Seq_LS180_Human1.09128792
99* JUN_21703547_ChIP-Seq_K562_Human1.08699859
100MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.07968349
101TCF4_23295773_ChIP-Seq_U87_Human1.07759952
102WT1_19549856_ChIP-ChIP_CCG9911_Human1.07712452
103TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05744465
104ERG_21242973_ChIP-ChIP_JURKAT_Human1.05590583
105* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.04367629
106SOX2_19829295_ChIP-Seq_ESCs_Human1.04272150
107NANOG_19829295_ChIP-Seq_ESCs_Human1.04272150
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.04259454
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03753913
110SMAD4_21741376_ChIP-Seq_EPCs_Human1.03325903
111NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.03289070
112ELK1_19687146_ChIP-ChIP_HELA_Human1.02921422
113PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02508069
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.02487709
115* AR_19668381_ChIP-Seq_PC3_Human1.01217433
116* NANOG_18555785_Chip-Seq_ESCs_Mouse1.00806919
117NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00319284
118SMAD_19615063_ChIP-ChIP_OVARY_Human1.00314998
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96893381
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96893381
121* ARNT_22903824_ChIP-Seq_MCF-7_Human0.96240034
122* EWS_26573619_Chip-Seq_HEK293_Human0.95771604
123* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93844603
124YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92485501
125* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91958594
126TP53_18474530_ChIP-ChIP_U2OS_Human0.90449517
127RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89782458
128* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89720359
129EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89549880
130SOX9_26525672_Chip-Seq_HEART_Mouse0.89398261
131AHR_22903824_ChIP-Seq_MCF-7_Human0.88869631
132MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88741152
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.87758158
134LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87322324
135* E2F1_18555785_Chip-Seq_ESCs_Mouse0.86579950
136* KDM2B_26808549_Chip-Seq_REH_Human0.86067268
137* CMYC_18555785_Chip-Seq_ESCs_Mouse0.84968400

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.95943919
2MP0004859_abnormal_synaptic_plasticity4.50863551
3MP0003635_abnormal_synaptic_transmissio3.44124173
4MP0006276_abnormal_autonomic_nervous3.07561925
5MP0009745_abnormal_behavioral_response3.00550796
6MP0001968_abnormal_touch/_nociception2.94037444
7MP0002063_abnormal_learning/memory/cond2.86984309
8MP0002064_seizures2.83294162
9MP0004270_analgesia2.82244459
10MP0003122_maternal_imprinting2.81231811
11MP0009046_muscle_twitch2.72931280
12MP0001529_abnormal_vocalization2.68244575
13MP0002572_abnormal_emotion/affect_behav2.63015321
14MP0005423_abnormal_somatic_nervous2.61694379
15MP0002234_abnormal_pharynx_morphology2.55369037
16MP0002734_abnormal_mechanical_nocicepti2.51412671
17MP0002736_abnormal_nociception_after2.45481572
18MP0001486_abnormal_startle_reflex2.42464730
19MP0002272_abnormal_nervous_system2.41839872
20MP0008877_abnormal_DNA_methylation2.38638125
21MP0001440_abnormal_grooming_behavior2.25054537
22MP0002822_catalepsy2.24411792
23MP0003283_abnormal_digestive_organ2.16649625
24MP0002735_abnormal_chemical_nociception2.10518271
25MP0000778_abnormal_nervous_system2.09048519
26MP0001501_abnormal_sleep_pattern2.07685067
27MP0001984_abnormal_olfaction2.06603856
28MP0005645_abnormal_hypothalamus_physiol2.03219640
29MP0002733_abnormal_thermal_nociception2.00189231
30MP0002067_abnormal_sensory_capabilities1.97259985
31MP0001970_abnormal_pain_threshold1.91867005
32MP0002184_abnormal_innervation1.90799122
33MP0001905_abnormal_dopamine_level1.83767685
34MP0002653_abnormal_ependyma_morphology1.78406091
35MP0002557_abnormal_social/conspecific_i1.75981721
36MP0005386_behavior/neurological_phenoty1.74506346
37MP0004924_abnormal_behavior1.74506346
38MP0003787_abnormal_imprinting1.67655291
39MP0004142_abnormal_muscle_tone1.65066886
40MP0005646_abnormal_pituitary_gland1.62983619
41MP0000372_irregular_coat_pigmentation1.60471658
42MP0001502_abnormal_circadian_rhythm1.57943650
43MP0005551_abnormal_eye_electrophysiolog1.53720435
44MP0001188_hyperpigmentation1.50353334
45MP0002938_white_spotting1.45666731
46MP0002882_abnormal_neuron_morphology1.44877887
47MP0000955_abnormal_spinal_cord1.44310964
48MP0004811_abnormal_neuron_physiology1.42305618
49MP0005248_abnormal_Harderian_gland1.41309292
50MP0002638_abnormal_pupillary_reflex1.39800964
51MP0002233_abnormal_nose_morphology1.37909853
52MP0003121_genomic_imprinting1.36421858
53MP0003329_amyloid_beta_deposits1.33877340
54MP0003119_abnormal_digestive_system1.31022274
55MP0002066_abnormal_motor_capabilities/c1.30829848
56MP0008569_lethality_at_weaning1.30317677
57MP0004858_abnormal_nervous_system1.26244160
58MP0004742_abnormal_vestibular_system1.24222307
59MP0001293_anophthalmia1.22006053
60MP0000751_myopathy1.18252656
61MP0000631_abnormal_neuroendocrine_gland1.16062580
62MP0002909_abnormal_adrenal_gland1.15434854
63MP0004133_heterotaxia1.12171589
64MP0002152_abnormal_brain_morphology1.10291290
65MP0009780_abnormal_chondrocyte_physiolo1.09665490
66MP0002752_abnormal_somatic_nervous1.07126129
67MP0006072_abnormal_retinal_apoptosis1.06573237
68MP0005391_vision/eye_phenotype1.06408534
69MP0010386_abnormal_urinary_bladder1.04328089
70MP0003011_delayed_dark_adaptation1.01851515
71MP0004885_abnormal_endolymph1.01367662
72MP0006292_abnormal_olfactory_placode1.00554091
73MP0003136_yellow_coat_color0.99486539
74MP0005499_abnormal_olfactory_system0.97904830
75MP0005394_taste/olfaction_phenotype0.97904830
76MP0001963_abnormal_hearing_physiology0.96296942
77MP0005187_abnormal_penis_morphology0.96274885
78MP0002229_neurodegeneration0.96209482
79MP0005171_absent_coat_pigmentation0.96122258
80MP0003879_abnormal_hair_cell0.95473055
81MP0004147_increased_porphyrin_level0.95044863
82MP0003195_calcinosis0.94358049
83MP0004085_abnormal_heartbeat0.93285798
84MP0000569_abnormal_digit_pigmentation0.92643723
85MP0005253_abnormal_eye_physiology0.92539345
86MP0004145_abnormal_muscle_electrophysio0.90310532
87MP0002751_abnormal_autonomic_nervous0.90062272
88MP0000462_abnormal_digestive_system0.88524110
89MP0004233_abnormal_muscle_weight0.87950540
90MP0002069_abnormal_eating/drinking_beha0.87165804
91MP0003634_abnormal_glial_cell0.87033286
92MP0003938_abnormal_ear_development0.86986630
93MP0003633_abnormal_nervous_system0.84338026
94MP0001299_abnormal_eye_distance/0.83476912
95MP0003631_nervous_system_phenotype0.82713183
96MP0000049_abnormal_middle_ear0.82405283
97MP0002090_abnormal_vision0.81900071
98MP0001324_abnormal_eye_pigmentation0.80437917
99MP0000920_abnormal_myelination0.78946542
100MP0000026_abnormal_inner_ear0.78492668
101MP0001177_atelectasis0.78267331
102MP0002876_abnormal_thyroid_physiology0.77298647
103MP0001286_abnormal_eye_development0.76917634
104MP0000427_abnormal_hair_cycle0.76343886
105MP0003755_abnormal_palate_morphology0.75577235
106MP0002102_abnormal_ear_morphology0.75318323
107MP0003937_abnormal_limbs/digits/tail_de0.74987065
108MP0005367_renal/urinary_system_phenotyp0.73839090
109MP0000516_abnormal_urinary_system0.73839090
110MP0006035_abnormal_mitochondrial_morpho0.72939967
111MP0003123_paternal_imprinting0.72497215
112MP0005379_endocrine/exocrine_gland_phen0.72242275
113MP0003890_abnormal_embryonic-extraembry0.71531880
114MP0002277_abnormal_respiratory_mucosa0.69623657
115MP0003567_abnormal_fetal_cardiomyocyte0.68945795
116MP0003137_abnormal_impulse_conducting0.68189793
117MP0008872_abnormal_physiological_respon0.67832699
118MP0001664_abnormal_digestion0.67150552
119MP0003861_abnormal_nervous_system0.67088613
120MP0003632_abnormal_nervous_system0.65629273
121MP0002837_dystrophic_cardiac_calcinosis0.65102471
122MP0001943_abnormal_respiration0.64427317
123MP0000013_abnormal_adipose_tissue0.63999999
124MP0005195_abnormal_posterior_eye0.63539265
125MP0001485_abnormal_pinna_reflex0.63463897
126MP0003183_abnormal_peptide_metabolism0.62485257
127MP0008789_abnormal_olfactory_epithelium0.60444153
128MP0004215_abnormal_myocardial_fiber0.59680217
129MP0008874_decreased_physiological_sensi0.56736536
130MP0001986_abnormal_taste_sensitivity0.56695006
131MP0005535_abnormal_body_temperature0.52353986
132MP0005409_darkened_coat_color0.51841625

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.57858859
2Myokymia (HP:0002411)5.30099495
3Epileptic encephalopathy (HP:0200134)4.82863487
4Focal seizures (HP:0007359)4.60117026
5Atonic seizures (HP:0010819)4.57290651
6Febrile seizures (HP:0002373)4.51736529
7Absence seizures (HP:0002121)3.73537099
8Abnormal hair whorl (HP:0010721)3.73264669
9Progressive cerebellar ataxia (HP:0002073)3.70760194
10Polyphagia (HP:0002591)3.69234636
11Visual hallucinations (HP:0002367)3.45119965
12Dialeptic seizures (HP:0011146)3.45072120
13Gait imbalance (HP:0002141)3.33015716
14Generalized tonic-clonic seizures (HP:0002069)3.32421582
15Pancreatic fibrosis (HP:0100732)3.14691955
16Hyperventilation (HP:0002883)2.99955731
17Pheochromocytoma (HP:0002666)2.97169795
18Abnormal eating behavior (HP:0100738)2.96263225
19Medial flaring of the eyebrow (HP:0010747)2.96182052
20Congenital primary aphakia (HP:0007707)2.93607569
21Failure to thrive in infancy (HP:0001531)2.93178952
22Broad-based gait (HP:0002136)2.92516731
23Limb dystonia (HP:0002451)2.91257581
24Nephrogenic diabetes insipidus (HP:0009806)2.76119676
25Supranuclear gaze palsy (HP:0000605)2.73629459
26True hermaphroditism (HP:0010459)2.70349392
27Drooling (HP:0002307)2.66105255
28Excessive salivation (HP:0003781)2.66105255
29Optic nerve hypoplasia (HP:0000609)2.63545102
30Ankle clonus (HP:0011448)2.61843196
31Pancreatic cysts (HP:0001737)2.60925393
32Abnormality of the corticospinal tract (HP:0002492)2.60352755
33Intestinal atresia (HP:0011100)2.58053506
34Neuroendocrine neoplasm (HP:0100634)2.57626048
35Dysdiadochokinesis (HP:0002075)2.56839892
36Amblyopia (HP:0000646)2.56283677
37Truncal ataxia (HP:0002078)2.55398452
38Progressive inability to walk (HP:0002505)2.54383975
39Abnormality of the labia minora (HP:0012880)2.54263615
40Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.54258921
41Degeneration of the lateral corticospinal tracts (HP:0002314)2.54258921
42Type II lissencephaly (HP:0007260)2.54192606
43Specific learning disability (HP:0001328)2.52326438
44Impaired vibration sensation in the lower limbs (HP:0002166)2.51135057
45Narrow nasal bridge (HP:0000446)2.50613799
46Poor suck (HP:0002033)2.50530781
47Action tremor (HP:0002345)2.49594883
48Esotropia (HP:0000565)2.49437792
49Nephronophthisis (HP:0000090)2.48939891
50Hemiparesis (HP:0001269)2.46865810
51Acute necrotizing encephalopathy (HP:0006965)2.46632796
52Anxiety (HP:0000739)2.44919359
53Vaginal atresia (HP:0000148)2.44379975
54Genital tract atresia (HP:0001827)2.43338657
55Hypoventilation (HP:0002791)2.39402650
56Dysmetria (HP:0001310)2.39188876
57Spastic gait (HP:0002064)2.37305340
58Termporal pattern (HP:0011008)2.37184625
59Insidious onset (HP:0003587)2.37184625
60Postaxial hand polydactyly (HP:0001162)2.35405798
61Epileptiform EEG discharges (HP:0011182)2.35217958
62Ketoacidosis (HP:0001993)2.33891894
63Gaze-evoked nystagmus (HP:0000640)2.31140771
64Urinary urgency (HP:0000012)2.27517979
65Neurofibrillary tangles (HP:0002185)2.27226181
66Short tibia (HP:0005736)2.26125503
67Depression (HP:0000716)2.25278354
68Hypoglycemic coma (HP:0001325)2.24887373
69EEG with generalized epileptiform discharges (HP:0011198)2.24857189
70Abnormal mitochondria in muscle tissue (HP:0008316)2.24466598
71Mutism (HP:0002300)2.23031996
72Ependymoma (HP:0002888)2.21134245
73Postaxial foot polydactyly (HP:0001830)2.20721675
74Aplasia/Hypoplasia of the tibia (HP:0005772)2.20668209
75Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.18352644
76Spastic tetraplegia (HP:0002510)2.18251576
77Agitation (HP:0000713)2.17762581
78Progressive macrocephaly (HP:0004481)2.16598162
79Urinary bladder sphincter dysfunction (HP:0002839)2.15625732
80Fetal akinesia sequence (HP:0001989)2.11092396
81Hypoglycemic seizures (HP:0002173)2.09304859
82Sleep apnea (HP:0010535)2.06626395
83Hypsarrhythmia (HP:0002521)2.05725608
84Astrocytoma (HP:0009592)2.05388305
85Abnormality of the astrocytes (HP:0100707)2.05388305
86Double outlet right ventricle (HP:0001719)2.05348406
87Congenital malformation of the right heart (HP:0011723)2.05348406
88Abnormal ciliary motility (HP:0012262)2.04403300
89Hyperinsulinemic hypoglycemia (HP:0000825)2.03333841
90Aplasia/Hypoplasia of the lens (HP:0008063)2.03280905
91Scanning speech (HP:0002168)2.02242167
92Abnormality of the renal medulla (HP:0100957)2.01110487
93Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.00661449
94Abnormality of midbrain morphology (HP:0002418)1.99102585
95Molar tooth sign on MRI (HP:0002419)1.99102585
96Hepatoblastoma (HP:0002884)1.98069049
97Pachygyria (HP:0001302)1.97999750
98Abnormality of the fovea (HP:0000493)1.96532487
99Cerebral inclusion bodies (HP:0100314)1.96332031
100Poor coordination (HP:0002370)1.96021974
101Absent speech (HP:0001344)1.94155747
102Poor eye contact (HP:0000817)1.93709800
103Aplasia/Hypoplasia of the tongue (HP:0010295)1.92830569
104Lower limb muscle weakness (HP:0007340)1.92541892
105Inability to walk (HP:0002540)1.90738841
106Lissencephaly (HP:0001339)1.90015842
107Abnormality of the metopic suture (HP:0005556)1.89945237
108Hypoplasia of the brainstem (HP:0002365)1.86286868
109Aplasia/Hypoplasia of the brainstem (HP:0007362)1.86286868
110Oligomenorrhea (HP:0000876)1.85541704
111Broad foot (HP:0001769)1.84570677
112Rhabdomyosarcoma (HP:0002859)1.84215323
113Protruding tongue (HP:0010808)1.84199556
114Hypothermia (HP:0002045)1.84151851
115Mitochondrial inheritance (HP:0001427)1.83761006
116Biliary tract neoplasm (HP:0100574)1.83738998
117Ulnar claw (HP:0001178)1.83135669
118Hip dysplasia (HP:0001385)1.82783779
119Hypoplasia of the fovea (HP:0007750)1.82350090
120Aplasia/Hypoplasia of the fovea (HP:0008060)1.82350090
121Optic disc pallor (HP:0000543)1.81874172
122Abnormality of the lower motor neuron (HP:0002366)1.81383465
123Psychosis (HP:0000709)1.80902478
124Abnormality of salivation (HP:0100755)1.80368811
125Short foot (HP:0001773)1.79985197
126Generalized myoclonic seizures (HP:0002123)1.79790904
127Retinal dysplasia (HP:0007973)1.79450325
128Akinesia (HP:0002304)1.78027955
129Impaired social interactions (HP:0000735)1.77230694
130Abnormal social behavior (HP:0012433)1.77230694
131Atrophy/Degeneration involving motor neurons (HP:0007373)1.76284382
132Exercise-induced muscle cramps (HP:0003710)1.76144254
133Severe Myopia (HP:0011003)1.75705138
134Renal cortical cysts (HP:0000803)1.75666899
135Septo-optic dysplasia (HP:0100842)1.75186798
136Shoulder girdle muscle weakness (HP:0003547)1.75067047
137Torticollis (HP:0000473)1.75031677
138Congenital stationary night blindness (HP:0007642)1.74855473
139Medulloblastoma (HP:0002885)1.74841505
140Occipital encephalocele (HP:0002085)1.73923185
141Abnormal respiratory motile cilium morphology (HP:0005938)1.72460279
142Abnormal respiratory epithelium morphology (HP:0012253)1.72460279
143Central scotoma (HP:0000603)1.71852200
144Blue irides (HP:0000635)1.71608913
145Narrow forehead (HP:0000341)1.70321828
146Dynein arm defect of respiratory motile cilia (HP:0012255)1.68969924
147Absent/shortened dynein arms (HP:0200106)1.68969924
148Growth hormone deficiency (HP:0000824)1.68816149
149Anophthalmia (HP:0000528)1.66513106
150Muscular hypotonia of the trunk (HP:0008936)1.65737143

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.87464560
2CASK4.02125015
3NTRK33.79073385
4TRIM283.54216617
5MARK13.44660876
6MAP3K43.10967430
7EPHA42.92272685
8MAP2K72.80935025
9MAP3K122.65632184
10MAP3K92.52378188
11MINK12.49699583
12NTRK22.37323033
13FRK2.33561977
14MAPK132.17007152
15SIK32.05633474
16TNIK1.77589721
17PNCK1.75115537
18BCR1.70593499
19MAP2K41.70571526
20PLK21.65166436
21PAK61.64979217
22KSR11.64607823
23NME11.61762982
24LATS11.55329134
25ARAF1.46788886
26GRK51.39786507
27OXSR11.37884715
28DAPK21.37074739
29GRK11.35965140
30CDK51.34985003
31NUAK11.32235734
32UHMK11.30634550
33CDK191.30258206
34PHKG11.26089864
35PHKG21.26089864
36PRKCG1.16151589
37CAMK2A1.15942394
38PRPF4B1.14763146
39KSR21.11406864
40SIK21.08886531
41RPS6KA41.08265521
42SGK4941.08153974
43SGK2231.08153974
44PRKD31.04302427
45WNK31.04095176
46CDK181.03326409
47BCKDK1.01232505
48CDK140.99376112
49CAMK2B0.98612713
50LIMK10.97907968
51NTRK10.97376537
52GRK70.96803332
53CSNK1G20.95598523
54CDK150.93866860
55TESK10.93732312
56STK390.93700957
57DYRK20.91940350
58DAPK10.90206339
59PKN10.90165716
60FGR0.89586507
61MAP3K130.88974586
62AKT30.88211290
63PAK30.88070670
64FES0.86891317
65DYRK30.86765940
66DYRK1A0.86130037
67RIPK40.84495742
68PRKCE0.81874419
69CDK11A0.80456652
70TYRO30.74513269
71CSNK1G30.74216343
72ADRBK10.71077281
73STK38L0.69830371
74MARK20.69819846
75CAMKK20.69374356
76LATS20.69311908
77NEK10.67129557
78PLK30.66978097
79CAMK2D0.66139805
80SGK20.64907829
81BMPR20.64766927
82CAMK10.64477645
83FGFR20.64401740
84INSRR0.58703249
85ROCK20.58611371
86EPHB20.58378364
87ERBB30.58259280
88CSNK1A10.58035375
89ADRBK20.57735033
90PINK10.57684943
91PTK2B0.56845940
92STK30.56415249
93BRAF0.55326002
94CAMK2G0.54525744
95NEK60.54457951
96SRPK10.54454981
97BMPR1B0.53205066
98CAMKK10.52817286
99IRAK20.52134280
100SGK10.51099819
101ACVR1B0.49894368
102TNK20.49502037
103PRKCZ0.48858977
104LMTK20.48392416
105PRKAA10.47575372
106STK380.45658767
107STK110.45600555
108PRKCH0.45420095
109FER0.44857362
110MKNK10.43901764
111PRKACA0.43611521
112MAPKAPK50.43455991
113MKNK20.43293526
114CSNK1D0.43096110
115CSNK1A1L0.42860743
116TSSK60.42832877
117CSNK1G10.42818604
118RAF10.42066602
119MUSK0.41935406
120MYLK0.41792700
121CAMK1G0.41317910
122CCNB10.40637622
123MAP3K50.38126436
124PRKG10.37844989
125CDK30.37648664
126CDC42BPA0.37549680
127NLK0.35802059
128PRKACB0.34364761
129EGFR0.31766260
130CAMK40.30729484
131DYRK1B0.28695655
132BRSK10.28480314
133PLK10.28197944
134RPS6KA50.27722408
135PIM20.26847340
136CSNK1E0.25841409

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.46186848
2Synaptic vesicle cycle_Homo sapiens_hsa047213.59510697
3Protein export_Homo sapiens_hsa030603.22594661
4GABAergic synapse_Homo sapiens_hsa047272.94317953
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.88482587
6Collecting duct acid secretion_Homo sapiens_hsa049662.63416030
7Morphine addiction_Homo sapiens_hsa050322.61349437
8Circadian entrainment_Homo sapiens_hsa047132.44875174
9Olfactory transduction_Homo sapiens_hsa047402.42241694
10Glutamatergic synapse_Homo sapiens_hsa047242.32986234
11Oxidative phosphorylation_Homo sapiens_hsa001902.29371401
12Maturity onset diabetes of the young_Homo sapiens_hsa049502.24099981
13Dopaminergic synapse_Homo sapiens_hsa047282.11005092
14Serotonergic synapse_Homo sapiens_hsa047262.05325252
15Amphetamine addiction_Homo sapiens_hsa050312.05057254
16Taste transduction_Homo sapiens_hsa047422.00799796
17Long-term potentiation_Homo sapiens_hsa047201.97269480
18Propanoate metabolism_Homo sapiens_hsa006401.81721217
19Vibrio cholerae infection_Homo sapiens_hsa051101.77634934
20Salivary secretion_Homo sapiens_hsa049701.77036623
21Cholinergic synapse_Homo sapiens_hsa047251.75692748
22Parkinsons disease_Homo sapiens_hsa050121.74438756
23Insulin secretion_Homo sapiens_hsa049111.73866496
24Steroid biosynthesis_Homo sapiens_hsa001001.69266854
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.68810606
26Long-term depression_Homo sapiens_hsa047301.67280321
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.66904208
28Cocaine addiction_Homo sapiens_hsa050301.66068091
29Cardiac muscle contraction_Homo sapiens_hsa042601.65398399
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.60632722
31Renin secretion_Homo sapiens_hsa049241.59097544
32Regulation of autophagy_Homo sapiens_hsa041401.58671002
33Alzheimers disease_Homo sapiens_hsa050101.55006774
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.52576835
35Calcium signaling pathway_Homo sapiens_hsa040201.46879821
36Axon guidance_Homo sapiens_hsa043601.40194607
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40117032
38Oxytocin signaling pathway_Homo sapiens_hsa049211.39653599
39Gastric acid secretion_Homo sapiens_hsa049711.37934796
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.36428788
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.35684601
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.33666944
43Gap junction_Homo sapiens_hsa045401.32042827
44Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.28928273
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.25890848
46Phototransduction_Homo sapiens_hsa047441.25819416
47Huntingtons disease_Homo sapiens_hsa050161.20271562
48Selenocompound metabolism_Homo sapiens_hsa004501.19766880
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18775011
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.17549143
51GnRH signaling pathway_Homo sapiens_hsa049121.12698574
52RNA polymerase_Homo sapiens_hsa030201.09219010
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03122116
54cAMP signaling pathway_Homo sapiens_hsa040241.03020182
55Tryptophan metabolism_Homo sapiens_hsa003801.00220778
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.95394863
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93590056
58Basal transcription factors_Homo sapiens_hsa030220.91942286
59Arginine and proline metabolism_Homo sapiens_hsa003300.89033684
60Melanogenesis_Homo sapiens_hsa049160.88580013
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87206941
62Peroxisome_Homo sapiens_hsa041460.85925567
63Rheumatoid arthritis_Homo sapiens_hsa053230.85255429
64ErbB signaling pathway_Homo sapiens_hsa040120.83951325
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.83604597
66Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.83002975
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81835530
68Non-homologous end-joining_Homo sapiens_hsa034500.79927764
69Dilated cardiomyopathy_Homo sapiens_hsa054140.79059171
70beta-Alanine metabolism_Homo sapiens_hsa004100.77880003
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76815058
72Pyruvate metabolism_Homo sapiens_hsa006200.76228357
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.75999988
74Estrogen signaling pathway_Homo sapiens_hsa049150.74371721
75Fatty acid metabolism_Homo sapiens_hsa012120.71525149
76SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70083999
77Hippo signaling pathway_Homo sapiens_hsa043900.70039883
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68707282
79Alcoholism_Homo sapiens_hsa050340.65702789
80Glioma_Homo sapiens_hsa052140.65673311
81Phagosome_Homo sapiens_hsa041450.65541718
82Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63715286
83Type II diabetes mellitus_Homo sapiens_hsa049300.62611832
84Oocyte meiosis_Homo sapiens_hsa041140.62007763
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61790002
86Basal cell carcinoma_Homo sapiens_hsa052170.60746335
87Fanconi anemia pathway_Homo sapiens_hsa034600.60348542
88Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.59558566
89Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.59121029
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.58889671
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58562909
92RNA degradation_Homo sapiens_hsa030180.58544171
93MAPK signaling pathway_Homo sapiens_hsa040100.58438238
94Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.58082729
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57865179
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.56636128
97Folate biosynthesis_Homo sapiens_hsa007900.55582959
98Ras signaling pathway_Homo sapiens_hsa040140.54940700
99Metabolic pathways_Homo sapiens_hsa011000.54933428
100Linoleic acid metabolism_Homo sapiens_hsa005910.53603935
101Circadian rhythm_Homo sapiens_hsa047100.53107823
102Vitamin B6 metabolism_Homo sapiens_hsa007500.52945959
103Type I diabetes mellitus_Homo sapiens_hsa049400.52532229
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51759225
105Purine metabolism_Homo sapiens_hsa002300.51732977
106Pancreatic secretion_Homo sapiens_hsa049720.50228406
107Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.50103895
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48508507
109Choline metabolism in cancer_Homo sapiens_hsa052310.48472916
110Nitrogen metabolism_Homo sapiens_hsa009100.48323733
111Cysteine and methionine metabolism_Homo sapiens_hsa002700.46528160
112Thyroid hormone synthesis_Homo sapiens_hsa049180.46497906
113Wnt signaling pathway_Homo sapiens_hsa043100.45554280
114Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.45126005
115Ether lipid metabolism_Homo sapiens_hsa005650.44147337
116Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43635393
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.42702630
118Renal cell carcinoma_Homo sapiens_hsa052110.41209614
119AMPK signaling pathway_Homo sapiens_hsa041520.41156763
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40398957
121Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40324559
122Dorso-ventral axis formation_Homo sapiens_hsa043200.39568878
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39477387
124Hedgehog signaling pathway_Homo sapiens_hsa043400.39293749
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.38749316
126Sulfur metabolism_Homo sapiens_hsa009200.38273702
127mRNA surveillance pathway_Homo sapiens_hsa030150.38012275
128N-Glycan biosynthesis_Homo sapiens_hsa005100.37794351
129Histidine metabolism_Homo sapiens_hsa003400.37053916
130Fatty acid degradation_Homo sapiens_hsa000710.36927353
131Butanoate metabolism_Homo sapiens_hsa006500.36299277
132Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36101982
133Ovarian steroidogenesis_Homo sapiens_hsa049130.33883197
134Rap1 signaling pathway_Homo sapiens_hsa040150.33171110
135Fatty acid elongation_Homo sapiens_hsa000620.32573039
136Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31866377
137Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30661230
138Neurotrophin signaling pathway_Homo sapiens_hsa047220.28677604
139Melanoma_Homo sapiens_hsa052180.28463485
140Prion diseases_Homo sapiens_hsa050200.27033937
141Glucagon signaling pathway_Homo sapiens_hsa049220.26929501
142Endocytosis_Homo sapiens_hsa041440.25815320
143Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25382508
144Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.21980871
145Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.21756684
146Sphingolipid metabolism_Homo sapiens_hsa006000.17783510
147Colorectal cancer_Homo sapiens_hsa052100.17462696

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