TOR4A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)7.10274090
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)7.10274090
3antigen processing and presentation of endogenous antigen (GO:0019883)6.37243859
4positive regulation of gamma-delta T cell activation (GO:0046645)5.60438211
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.23942037
6response to peptidoglycan (GO:0032494)4.53183495
7regulation of B cell receptor signaling pathway (GO:0050855)4.48602566
8regulation of gamma-delta T cell differentiation (GO:0045586)4.42868551
9positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.39909222
10regulation of gamma-delta T cell activation (GO:0046643)4.10896136
11antigen processing and presentation via MHC class Ib (GO:0002475)4.02961137
12positive regulation of B cell differentiation (GO:0045579)3.97236568
13Arp2/3 complex-mediated actin nucleation (GO:0034314)3.95237782
14modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.84938729
15positive regulation by organism of defense response of other organism involved in symbiotic interact3.84938729
16modulation by symbiont of host immune response (GO:0052553)3.84938729
17positive regulation by symbiont of host defense response (GO:0052509)3.84938729
18modulation by symbiont of host defense response (GO:0052031)3.84938729
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.84938729
20protein localization to endosome (GO:0036010)3.84275590
21regulation of interferon-beta biosynthetic process (GO:0045357)3.81666443
22negative regulation of phagocytosis (GO:0050765)3.73780021
23positive regulation of Cdc42 GTPase activity (GO:0043089)3.67556861
24leukocyte aggregation (GO:0070486)3.65530814
25regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.65075893
26positive thymic T cell selection (GO:0045059)3.62556319
27regulation of B cell differentiation (GO:0045577)3.53446536
28negative regulation of erythrocyte differentiation (GO:0045647)3.45656326
29immunoglobulin mediated immune response (GO:0016064)3.43469182
30B cell receptor signaling pathway (GO:0050853)3.40806687
31barbed-end actin filament capping (GO:0051016)3.40380370
32regulation of interleukin-12 biosynthetic process (GO:0045075)3.34151312
33negative thymic T cell selection (GO:0045060)3.29739417
34activation of Rac GTPase activity (GO:0032863)3.29217300
35negative T cell selection (GO:0043383)3.26956633
36response to interleukin-15 (GO:0070672)3.24910729
37lipopolysaccharide-mediated signaling pathway (GO:0031663)3.24692506
38ribosomal small subunit assembly (GO:0000028)3.17975211
39negative regulation of cell killing (GO:0031342)3.13220826
40negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.13220826
41stress fiber assembly (GO:0043149)3.08835327
42response to type I interferon (GO:0034340)3.08497673
43regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.07654703
44positive regulation of interferon-alpha production (GO:0032727)3.03542591
45T cell migration (GO:0072678)3.03519107
46cellular extravasation (GO:0045123)3.02144442
47regulation of early endosome to late endosome transport (GO:2000641)3.02133239
48hepatocyte apoptotic process (GO:0097284)3.01455138
49hemidesmosome assembly (GO:0031581)3.00862859
50cellular response to type I interferon (GO:0071357)2.99683677
51type I interferon signaling pathway (GO:0060337)2.99683677
52definitive hemopoiesis (GO:0060216)2.99358264
53negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.95346500
54thymic T cell selection (GO:0045061)2.94624266
55pinocytosis (GO:0006907)2.94181376
56megakaryocyte development (GO:0035855)2.91882510
57neutrophil activation involved in immune response (GO:0002283)2.90761743
58actin nucleation (GO:0045010)2.89771862
59response to muramyl dipeptide (GO:0032495)2.89199887
60regulation of interferon-alpha production (GO:0032647)2.87486064
61positive regulation of antigen processing and presentation (GO:0002579)2.87229526
62response to interferon-beta (GO:0035456)2.87145649
63T cell homeostasis (GO:0043029)2.86946636
64respiratory burst (GO:0045730)2.86645686
65positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.86619213
66leukocyte cell-cell adhesion (GO:0007159)2.86577764
67regulation of leukocyte degranulation (GO:0043300)2.86085576
68regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.85804691
69regulation of integrin activation (GO:0033623)2.85573661
70positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.85513464
71interferon-gamma production (GO:0032609)2.81996327
72macrophage activation involved in immune response (GO:0002281)2.81724395
73detection of other organism (GO:0098543)2.79615630
74mast cell activation (GO:0045576)2.79378929
75negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.78464762
76regulation of mast cell degranulation (GO:0043304)2.78048211
77positive regulation of macrophage differentiation (GO:0045651)2.77851030
78positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.77693514
79mannose metabolic process (GO:0006013)2.77540352
80response to laminar fluid shear stress (GO:0034616)2.76417336
81B cell mediated immunity (GO:0019724)2.76331171
82response to protozoan (GO:0001562)2.75767641
83NIK/NF-kappaB signaling (GO:0038061)2.75163810
84positive regulation of receptor recycling (GO:0001921)2.74275225
85negative regulation of interleukin-12 production (GO:0032695)2.74018916
86regulation of type I interferon-mediated signaling pathway (GO:0060338)2.73667206
87skin morphogenesis (GO:0043589)2.72483287
88apoptotic process involved in morphogenesis (GO:0060561)2.72450596
89interferon-gamma-mediated signaling pathway (GO:0060333)2.70691537
90mesodermal cell differentiation (GO:0048333)2.70663586
91JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.70421291
92myeloid dendritic cell activation (GO:0001773)2.69729450
93detection of bacterium (GO:0016045)2.68156894
94tolerance induction (GO:0002507)2.67759794
95regulation of myeloid leukocyte mediated immunity (GO:0002886)2.67212675
96regulation of response to interferon-gamma (GO:0060330)2.66015967
97hypotonic response (GO:0006971)2.64158447
98germinal center formation (GO:0002467)2.63893623
99regulation of T cell receptor signaling pathway (GO:0050856)2.63014947
100COPI coating of Golgi vesicle (GO:0048205)2.62639579
101Golgi transport vesicle coating (GO:0048200)2.62639579
102cellular response to interleukin-15 (GO:0071350)2.62261449
103myeloid cell activation involved in immune response (GO:0002275)2.62034956
104T cell selection (GO:0045058)2.61896919
105positive T cell selection (GO:0043368)2.61752264
106response to interferon-alpha (GO:0035455)2.61297437
107antigen receptor-mediated signaling pathway (GO:0050851)2.60902915
108glycosphingolipid catabolic process (GO:0046479)2.60141413
109negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.58864019
110hyaluronan catabolic process (GO:0030214)2.57899488
111regulation of necroptotic process (GO:0060544)2.57860096
112positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.57379380
113regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.56856540
114cell-substrate junction assembly (GO:0007044)2.56765856
115defense response to protozoan (GO:0042832)2.56308417
116lymphocyte homeostasis (GO:0002260)2.55981465
117angiogenesis involved in wound healing (GO:0060055)2.55266463
118positive regulation of lamellipodium assembly (GO:0010592)2.55110398
119response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.55017522
120response to host immune response (GO:0052572)2.55017522
121epithelial cell-cell adhesion (GO:0090136)2.54857617
122regulation of dendritic cell antigen processing and presentation (GO:0002604)2.52736908
123viral transcription (GO:0019083)2.52418487
124negative regulation of viral release from host cell (GO:1902187)2.52041934
125T cell costimulation (GO:0031295)2.50244847
126response to progesterone (GO:0032570)2.50109168
127regulation of antigen processing and presentation (GO:0002577)2.50069494
128response to host (GO:0075136)2.49319303
129response to host defenses (GO:0052200)2.49319303
130response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.49319303
131regulation of extracellular matrix disassembly (GO:0010715)2.49039404
132negative regulation of granulocyte differentiation (GO:0030853)2.48450155
133lymphocyte costimulation (GO:0031294)2.48374452
134pentose-phosphate shunt (GO:0006098)2.48105893
135positive regulation of tolerance induction (GO:0002645)2.47422982
136positive regulation of natural killer cell differentiation (GO:0032825)2.46401424
137detection of external biotic stimulus (GO:0098581)2.46182452
138modulation by symbiont of host cellular process (GO:0044068)2.45853511
139regulation of superoxide anion generation (GO:0032928)2.45177659
140positive regulation of histone deacetylation (GO:0031065)2.45130997
141myeloid dendritic cell differentiation (GO:0043011)2.44683206
142apoptotic cell clearance (GO:0043277)2.43978974
143regulation of mast cell activation involved in immune response (GO:0033006)2.43514493
144adhesion of symbiont to host cell (GO:0044650)2.43407210
145virion attachment to host cell (GO:0019062)2.43407210
146detection of molecule of bacterial origin (GO:0032490)2.43316866
147regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.43028848
148glucose catabolic process (GO:0006007)2.39385055
149T-helper 1 type immune response (GO:0042088)2.37380327
150adhesion of symbiont to host (GO:0044406)2.35115121
151peptide catabolic process (GO:0043171)2.34437094
152regulation of apoptotic process involved in morphogenesis (GO:1902337)2.34412432
153glucose 6-phosphate metabolic process (GO:0051156)2.32452678
154cell adhesion mediated by integrin (GO:0033627)2.32298985
155positive regulation of transcription factor import into nucleus (GO:0042993)2.32278241
156regulation of T-helper 2 cell differentiation (GO:0045628)2.32200199
157regulation of podosome assembly (GO:0071801)2.31251122
158basement membrane organization (GO:0071711)2.30164227
159regulation of vitamin D biosynthetic process (GO:0060556)2.30102702
160glycolipid catabolic process (GO:0019377)2.30041713
161vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.27891568
162regulation of viral release from host cell (GO:1902186)2.27773442
163branching involved in mammary gland duct morphogenesis (GO:0060444)2.27139859
164positive regulation of extracellular matrix organization (GO:1903055)2.26903416
165regulation of membrane protein ectodomain proteolysis (GO:0051043)2.24478823

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.25298270
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.38833740
3MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.32842345
4E2F7_22180533_ChIP-Seq_HELA_Human3.31109543
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.25610666
6IRF8_21731497_ChIP-ChIP_J774_Mouse3.23901768
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.13694102
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.05442090
9MYC_22102868_ChIP-Seq_BL_Human2.90103121
10SCL_19346495_ChIP-Seq_HPC-7_Human2.75051392
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.69846330
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.69333151
13VDR_21846776_ChIP-Seq_THP-1_Human2.68419073
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.65201531
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.57699985
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.46191845
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.46114809
18NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.43975187
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.41618581
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.40955497
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40610430
22ZNF263_19887448_ChIP-Seq_K562_Human2.31613690
23MAF_26560356_Chip-Seq_TH1_Human2.30302780
24MYB_26560356_Chip-Seq_TH2_Human2.27756643
25* SPI1_23547873_ChIP-Seq_NB4_Human2.23957027
26STAT4_19710469_ChIP-ChIP_TH1__Mouse2.21149064
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.20608960
28STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.12789006
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.10733512
30BRD4_27068464_Chip-Seq_AML-cells_Mouse2.07351538
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.05505146
32VDR_24763502_ChIP-Seq_THP-1_Human2.04637943
33UTX_26944678_Chip-Seq_JUKART_Human2.03538950
34MYB_26560356_Chip-Seq_TH1_Human2.01779968
35RUNX1_22412390_ChIP-Seq_EML_Mouse2.00983283
36RACK7_27058665_Chip-Seq_MCF-7_Human2.00244733
37RUNX_20019798_ChIP-Seq_JUKART_Human2.00135167
38FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.99017701
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.98305542
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.96695457
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.90334848
42TCF7_22412390_ChIP-Seq_EML_Mouse1.85821427
43TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.84141951
44ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79021746
45E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.76888959
46KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.75586998
47SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.68797923
48MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.65867172
49TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.62499125
50SPI1_23127762_ChIP-Seq_K562_Human1.61691052
51GATA1_22025678_ChIP-Seq_K562_Human1.57202565
52STAT6_21828071_ChIP-Seq_BEAS2B_Human1.55772951
53ELK3_25401928_ChIP-Seq_HUVEC_Human1.54066918
54RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.53994710
55LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.49101746
56RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.46938030
57GATA1_22383799_ChIP-Seq_G1ME_Mouse1.46815127
58MAF_26560356_Chip-Seq_TH2_Human1.46262237
59GATA2_22383799_ChIP-Seq_G1ME_Mouse1.45196403
60UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.45034419
61ERG_20887958_ChIP-Seq_HPC-7_Mouse1.44163510
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.44058906
63KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.43638122
64KDM2B_26808549_Chip-Seq_K562_Human1.43448740
65ATF3_27146783_Chip-Seq_COLON_Human1.37560799
66GATA3_27048872_Chip-Seq_THYMUS_Human1.36012038
67P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35303073
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.35216679
69KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.35081977
70CTCF_27219007_Chip-Seq_ERYTHROID_Human1.33717962
71TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.32961567
72TP53_22127205_ChIP-Seq_IMR90_Human1.29278637
73STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.29030124
74GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.28932357
75LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.28253838
76PU_27001747_Chip-Seq_BMDM_Mouse1.27312830
77KDM2B_26808549_Chip-Seq_DND41_Human1.25706221
78KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24974625
79CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24071910
80GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.22684494
81KDM2B_26808549_Chip-Seq_JURKAT_Human1.22569631
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21511054
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21151678
84TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18922733
85Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.17960026
86CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.17005442
87CIITA_25753668_ChIP-Seq_RAJI_Human1.16759296
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.16300574
89CLOCK_20551151_ChIP-Seq_293T_Human1.15896955
90ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.15498963
91CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15256084
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.15242556
93TET1_21451524_ChIP-Seq_MESCs_Mouse1.14953276
94P68_20966046_ChIP-Seq_HELA_Human1.14849746
95KDM2B_26808549_Chip-Seq_SUP-B15_Human1.14050502
96EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13973788
97ESR2_21235772_ChIP-Seq_MCF-7_Human1.13864104
98SRY_22984422_ChIP-ChIP_TESTIS_Rat1.13257318
99FOXM1_23109430_ChIP-Seq_U2OS_Human1.13242384
100P63_26484246_Chip-Seq_KERATINOCYTES_Human1.13140024
101HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12806512
102BCOR_27268052_Chip-Seq_Bcells_Human1.12274087
103PPARA_22158963_ChIP-Seq_LIVER_Mouse1.11649907
104UBF1/2_26484160_Chip-Seq_HMECs_Human1.09702991
105TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.07940710
106SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.07802157
107PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06776309
108GATA1_19941827_ChIP-Seq_MEL_Mouse1.06548951
109SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.06055453
110SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.06055453
111ELF1_20517297_ChIP-Seq_JURKAT_Human1.05371535
112SOX2_27498859_Chip-Seq_STOMACH_Mouse1.03362846
113SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03149779
114STAT3_1855785_ChIP-Seq_MESCs_Mouse1.02998173
115NCOR1_26117541_ChIP-Seq_K562_Human1.02793848
116TFEB_21752829_ChIP-Seq_HELA_Human1.01828372
117LXR_22292898_ChIP-Seq_THP-1_Human1.00585500
118EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.00089127
119RXR_22158963_ChIP-Seq_LIVER_Mouse0.99401978
120PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98506944
121HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97929371
122TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96708197
123GATA2_21666600_ChIP-Seq_HMVEC_Human0.96649477
124THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96503156
125ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.95821414
126GATA3_26560356_Chip-Seq_TH2_Human0.92115926
127PU.1_20513432_ChIP-Seq_Bcells_Mouse0.92107935
128SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89718927
129CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89393271
130VDR_23849224_ChIP-Seq_CD4+_Human0.88891855
131MYC_18555785_ChIP-Seq_MESCs_Mouse0.88080827
132FOXP3_21729870_ChIP-Seq_TREG_Human0.87878841
133KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.86017548
134GATA1_19941826_ChIP-Seq_K562_Human0.84634825
135CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.84404013
136PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.83699041
137TP63_17297297_ChIP-ChIP_HaCaT_Human0.83253470
138GATA2_19941826_ChIP-Seq_K562_Human0.82132422
139SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.80222808
140PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80088989
141NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.79754603
142E2F4_17652178_ChIP-ChIP_JURKAT_Human0.79288415
143BCL6_27268052_Chip-Seq_Bcells_Human0.76379897
144E2F1_21310950_ChIP-Seq_MCF-7_Human0.76255225
145FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.74612343

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.52220174
2MP0000685_abnormal_immune_system2.97826794
3MP0005671_abnormal_response_to2.81190654
4MP0003436_decreased_susceptibility_to2.79638659
5MP0001800_abnormal_humoral_immune2.62677762
6MP0005451_abnormal_body_composition2.57765331
7MP0002396_abnormal_hematopoietic_system2.56296747
8MP0005387_immune_system_phenotype2.51174334
9MP0001790_abnormal_immune_system2.51174334
10MP0003300_gastrointestinal_ulcer2.50527163
11MP0009785_altered_susceptibility_to2.50454830
12MP0003763_abnormal_thymus_physiology2.44790807
13MP0003303_peritoneal_inflammation2.44339168
14MP0002452_abnormal_antigen_presenting2.42366019
15MP0005000_abnormal_immune_tolerance2.40057959
16MP0005025_abnormal_response_to2.39943898
17MP0002420_abnormal_adaptive_immunity2.32520773
18MP0005464_abnormal_platelet_physiology2.30168586
19MP0001819_abnormal_immune_cell2.30154121
20MP0002419_abnormal_innate_immunity2.27175324
21MP0002723_abnormal_immune_serum2.26560600
22MP0003724_increased_susceptibility_to2.20295845
23MP0002166_altered_tumor_susceptibility2.19300286
24MP0000465_gastrointestinal_hemorrhage2.19248782
25MP0005058_abnormal_lysosome_morphology2.18418301
26MP0002398_abnormal_bone_marrow2.15403484
27MP0004808_abnormal_hematopoietic_stem2.14805820
28MP0001849_ear_inflammation2.01087154
29MP0008438_abnormal_cutaneous_collagen2.00047717
30MP0006082_CNS_inflammation1.99345491
31MP0000716_abnormal_immune_system1.97177171
32MP0001873_stomach_inflammation1.95256967
33MP0002405_respiratory_system_inflammati1.95235316
34MP0010155_abnormal_intestine_physiology1.94792160
35MP0009333_abnormal_splenocyte_physiolog1.93097651
36MP0000689_abnormal_spleen_morphology1.92700138
37MP0002148_abnormal_hypersensitivity_rea1.88791546
38MP0002722_abnormal_immune_system1.84714795
39MP0006054_spinal_hemorrhage1.83338592
40MP0009278_abnormal_bone_marrow1.81491645
41MP0005397_hematopoietic_system_phenotyp1.80612359
42MP0001545_abnormal_hematopoietic_system1.80612359
43MP0005076_abnormal_cell_differentiation1.75943190
44MP0008260_abnormal_autophagy1.74786734
45MP0002429_abnormal_blood_cell1.72640050
46MP0004947_skin_inflammation1.70645424
47MP0001845_abnormal_inflammatory_respons1.69725591
48MP0003172_abnormal_lysosome_physiology1.68296556
49MP0005257_abnormal_intraocular_pressure1.64988203
50MP0000490_abnormal_crypts_of1.58967464
51MP0003191_abnormal_cellular_cholesterol1.57627329
52MP0001853_heart_inflammation1.56912314
53MP0002006_tumorigenesis1.56228775
54MP0001533_abnormal_skeleton_physiology1.53383051
55MP0003866_abnormal_defecation1.53095584
56MP0000703_abnormal_thymus_morphology1.50651546
57MP0004272_abnormal_basement_membrane1.50537983
58MP0000858_altered_metastatic_potential1.44163200
59MP0002933_joint_inflammation1.42794816
60MP0010352_gastrointestinal_tract_polyps1.42563010
61MP0003566_abnormal_cell_adhesion1.33006234
62MP0008469_abnormal_protein_level1.32729672
63MP0009840_abnormal_foam_cell1.31648534
64MP0005164_abnormal_response_to1.26400828
65MP0010307_abnormal_tumor_latency1.23515370
66MP0005310_abnormal_salivary_gland1.22249177
67MP0005174_abnormal_tail_pigmentation1.22177206
68MP0003448_altered_tumor_morphology1.16691548
69MP0005023_abnormal_wound_healing1.15446677
70MP0002139_abnormal_hepatobiliary_system1.13625736
71MP0001851_eye_inflammation1.12762508
72MP0000343_altered_response_to1.12752165
73MP0003183_abnormal_peptide_metabolism1.12351442
74MP0004510_myositis1.10336727
75MP0002877_abnormal_melanocyte_morpholog1.10205795
76MP0004185_abnormal_adipocyte_glucose1.05609256
77MP0001348_abnormal_lacrimal_gland1.05092758
78MP0005360_urolithiasis1.04812870
79MP0008004_abnormal_stomach_pH1.04006602
80MP0004858_abnormal_nervous_system1.02999235
81MP0004883_abnormal_blood_vessel0.99398681
82MP0001542_abnormal_bone_strength0.98113581
83MP0002019_abnormal_tumor_incidence0.97864152
84MP0002060_abnormal_skin_morphology0.96446229
85MP0005595_abnormal_vascular_smooth0.91048051
86MP0002796_impaired_skin_barrier0.90475920
87MP0002138_abnormal_hepatobiliary_system0.90071185
88MP0002896_abnormal_bone_mineralization0.89590383
89MP0003075_altered_response_to0.89155117
90MP0005165_increased_susceptibility_to0.88365699
91MP0005501_abnormal_skin_physiology0.87399514
92MP0000604_amyloidosis0.86814648
93MP0003656_abnormal_erythrocyte_physiolo0.85664574
94MP0010234_abnormal_vibrissa_follicle0.84877272
95MP0001216_abnormal_epidermal_layer0.83936357
96MP0003828_pulmonary_edema0.83811147
97MP0003279_aneurysm0.83738300
98MP0002254_reproductive_system_inflammat0.82796829
99MP0005075_abnormal_melanosome_morpholog0.82391577
100MP0009764_decreased_sensitivity_to0.81633578
101MP0001958_emphysema0.81284530
102MP0009763_increased_sensitivity_to0.81134787
103MP0001915_intracranial_hemorrhage0.78729320
104MP0002998_abnormal_bone_remodeling0.78000586
105MP0003705_abnormal_hypodermis_morpholog0.77579269
106MP0003950_abnormal_plasma_membrane0.76764973
107MP0000249_abnormal_blood_vessel0.76442929
108MP0003693_abnormal_embryo_hatching0.75443549
109MP0000477_abnormal_intestine_morphology0.74176795
110MP0010368_abnormal_lymphatic_system0.71584886
111MP0001663_abnormal_digestive_system0.71126371
112MP0005390_skeleton_phenotype0.70843251
113MP0005166_decreased_susceptibility_to0.70180543
114MP0002136_abnormal_kidney_physiology0.69739159
115MP0002132_abnormal_respiratory_system0.68982500
116MP0001879_abnormal_lymphatic_vessel0.68401373
117MP0003795_abnormal_bone_structure0.67086776
118MP0003943_abnormal_hepatobiliary_system0.66893885
119MP0000598_abnormal_liver_morphology0.66236382
120MP0003091_abnormal_cell_migration0.65016022
121MP0000609_abnormal_liver_physiology0.64118994
122MP0008007_abnormal_cellular_replicative0.64107676
123MP0009643_abnormal_urine_homeostasis0.58400504
124MP0000313_abnormal_cell_death0.57683650
125MP0000767_abnormal_smooth_muscle0.57462150
126MP0003453_abnormal_keratinocyte_physiol0.56564360
127MP0003045_fibrosis0.55895416
128MP0004264_abnormal_extraembryonic_tissu0.55713939

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.42131884
2Chronic otitis media (HP:0000389)4.34790012
3Eczematoid dermatitis (HP:0000976)4.29739027
4Thrombocytosis (HP:0001894)4.17596385
5IgM deficiency (HP:0002850)4.09678178
6Myositis (HP:0100614)3.81716353
7Recurrent bacterial skin infections (HP:0005406)3.78493035
8Recurrent bronchitis (HP:0002837)3.75369598
9Elevated erythrocyte sedimentation rate (HP:0003565)3.65724924
10Abnormality of the nasal mucosa (HP:0000433)3.64683165
11Nasal polyposis (HP:0100582)3.60223604
12Recurrent viral infections (HP:0004429)3.59027143
13Vacuolated lymphocytes (HP:0001922)3.56192099
14Recurrent fungal infections (HP:0002841)3.53477327
15Spontaneous hematomas (HP:0007420)3.46253273
16Protrusio acetabuli (HP:0003179)3.45798367
17Premature rupture of membranes (HP:0001788)3.43272676
18Cellulitis (HP:0100658)3.34378667
19Hemorrhage of the eye (HP:0011885)3.27366085
20Petechiae (HP:0000967)3.25171509
21Abnormality of macrophages (HP:0004311)3.23552880
22Abnormal delayed hypersensitivity skin test (HP:0002963)3.20259426
23Gastrointestinal inflammation (HP:0004386)3.16064301
24Distal lower limb amyotrophy (HP:0008944)3.14788506
25Prolonged bleeding time (HP:0003010)3.14101894
26Interstitial pulmonary disease (HP:0006530)3.14084086
27Inflammation of the large intestine (HP:0002037)3.14023269
28Increased cerebral lipofuscin (HP:0011813)3.12081896
29Fragile skin (HP:0001030)3.11140249
30Pustule (HP:0200039)3.05702500
31Dysostosis multiplex (HP:0000943)2.98045693
32Abnormality of T cells (HP:0002843)2.94235501
33Abnormality of T cell physiology (HP:0011840)2.93253264
34Hematochezia (HP:0002573)2.92538785
35Recurrent skin infections (HP:0001581)2.88947188
36Meningitis (HP:0001287)2.87475759
37Epistaxis (HP:0000421)2.85846945
38Increased neuronal autofluorescent lipopigment (HP:0002074)2.84759507
39T lymphocytopenia (HP:0005403)2.84477687
40Increased connective tissue (HP:0009025)2.77810852
41Recurrent gram-negative bacterial infections (HP:0005420)2.75357560
42Orchitis (HP:0100796)2.72381119
43Colitis (HP:0002583)2.71426251
44Abnormality of T cell number (HP:0011839)2.71268202
45Chronic mucocutaneous candidiasis (HP:0002728)2.68915723
46Recurrent cutaneous fungal infections (HP:0011370)2.68915723
47Vertebral compression fractures (HP:0002953)2.68329663
48Impaired platelet aggregation (HP:0003540)2.67327314
49Abnormal platelet function (HP:0011869)2.67327314
50Panhypogammaglobulinemia (HP:0003139)2.65900500
51Autoimmune thrombocytopenia (HP:0001973)2.60978199
52Agammaglobulinemia (HP:0004432)2.59987392
53Mucopolysacchariduria (HP:0008155)2.59576971
54Urinary glycosaminoglycan excretion (HP:0003541)2.59576971
55Lymphopenia (HP:0001888)2.58686053
56Arterial thrombosis (HP:0004420)2.58230103
57Atrophic scars (HP:0001075)2.57188003
58Periodontitis (HP:0000704)2.53885203
59Abnormality of cells of the lymphoid lineage (HP:0012140)2.49184477
60Vasculitis (HP:0002633)2.48757668
61Axonal loss (HP:0003447)2.46637743
62Broad face (HP:0000283)2.45690781
63Obstructive lung disease (HP:0006536)2.45038067
64Chronic obstructive pulmonary disease (HP:0006510)2.45038067
65Mediastinal lymphadenopathy (HP:0100721)2.44681798
66Abnormal platelet volume (HP:0011876)2.43978344
67Gingival bleeding (HP:0000225)2.43957468
68Chest pain (HP:0100749)2.42723808
69Systemic lupus erythematosus (HP:0002725)2.42038389
70Upper limb amyotrophy (HP:0009129)2.41932987
71Distal upper limb amyotrophy (HP:0007149)2.41932987
72Abnormality of mucopolysaccharide metabolism (HP:0011020)2.38760593
73Abnormality of polysaccharide metabolism (HP:0011012)2.38760593
74Abnormality of glycosaminoglycan metabolism (HP:0004371)2.38760593
75Myocardial infarction (HP:0001658)2.37638790
76Achilles tendon contracture (HP:0001771)2.32639554
77B lymphocytopenia (HP:0010976)2.32476401
78Abnormality of B cell number (HP:0010975)2.32476401
79Premature loss of primary teeth (HP:0006323)2.31960840
80Osteomyelitis (HP:0002754)2.29230296
81Verrucae (HP:0200043)2.27980631
82Papilloma (HP:0012740)2.27980631
83Cervical subluxation (HP:0003308)2.26991011
84Cerebral aneurysm (HP:0004944)2.25519299
85Difficulty climbing stairs (HP:0003551)2.25433128
86Fatigue (HP:0012378)2.25182061
87Increased IgE level (HP:0003212)2.25122885
88Leukocytosis (HP:0001974)2.24250587
89Loss of speech (HP:0002371)2.20089012
90Bronchitis (HP:0012387)2.19774561
91Purpura (HP:0000979)2.19639040
92Gastrointestinal stroma tumor (HP:0100723)2.17366393
93Emphysema (HP:0002097)2.15311529
94Hyperacusis (HP:0010780)2.14914044
95Aneurysm (HP:0002617)2.14078951
96Chronic diarrhea (HP:0002028)2.13985139
97Thin bony cortex (HP:0002753)2.13778612
98IgG deficiency (HP:0004315)2.12806055
99Retrobulbar optic neuritis (HP:0100654)2.12790646
100Optic neuritis (HP:0100653)2.12790646
101Peritonitis (HP:0002586)2.11966810
102Aplastic anemia (HP:0001915)2.11080728
103Polycythemia (HP:0001901)2.10312285
104Granulocytopenia (HP:0001913)2.09935803
105Easy fatigability (HP:0003388)2.08413985
106Thoracic kyphosis (HP:0002942)2.07018520
107Skin ulcer (HP:0200042)2.06936322
108Abnormality of the Achilles tendon (HP:0005109)2.06264892
109IgA deficiency (HP:0002720)2.05860444
110Increased serum ferritin (HP:0003281)2.05758464
111Gingivitis (HP:0000230)2.04946211
112Hemoptysis (HP:0002105)2.04680931
113Chronic sinusitis (HP:0011109)2.04421820
114Increased density of long bones (HP:0006392)2.04419479
115Distal lower limb muscle weakness (HP:0009053)2.02441775
116Spinal rigidity (HP:0003306)2.02219001
117Abnormality of the thoracic spine (HP:0100711)2.01761557
118Flat acetabular roof (HP:0003180)2.01659909
119Nuclear cataract (HP:0100018)2.01542730
120Bone pain (HP:0002653)2.01415325
121Dilatation of the ascending aorta (HP:0005111)2.01063267
122Amaurosis fugax (HP:0100576)2.00628774
123Disproportionate tall stature (HP:0001519)2.00043840
124Encephalitis (HP:0002383)1.97970203
125Amyloidosis (HP:0011034)1.97724935
126Eosinophilia (HP:0001880)1.97647111
127Increased mean platelet volume (HP:0011877)1.96692542
128Mildly elevated creatine phosphokinase (HP:0008180)1.96424760
129Blue sclerae (HP:0000592)1.96285975
130Upper motor neuron abnormality (HP:0002127)1.95277623
131Pathologic fracture (HP:0002756)1.94977095
132Spondylolisthesis (HP:0003302)1.94447753
133Arterial tortuosity (HP:0005116)1.92981653
134Abnormality of liposaccharide metabolism (HP:0010968)1.92711807
135Abnormality of glycosphingolipid metabolism (HP:0004343)1.92711807
136Abnormality of glycolipid metabolism (HP:0010969)1.92711807
137Pulmonary infiltrates (HP:0002113)1.92136541
138Hypertensive crisis (HP:0100735)1.91931402
139Short nail (HP:0001799)1.91720731
140Vascular tortuosity (HP:0004948)1.91428020
141Malnutrition (HP:0004395)1.90599009
142Lower limb amyotrophy (HP:0007210)1.89700976
143Menorrhagia (HP:0000132)1.89053551
144Osteolytic defects of the hand bones (HP:0009699)1.88928703
145Osteolytic defects of the phalanges of the hand (HP:0009771)1.87512282
146Hypertriglyceridemia (HP:0002155)1.86628590
147Ulnar bowing (HP:0003031)1.79710580
148Aortic aneurysm (HP:0004942)1.79499889
149Milia (HP:0001056)1.75094719
150Wormian bones (HP:0002645)1.71629503
151Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.71568276
152Abnormality of oral frenula (HP:0000190)1.71035739
153Stridor (HP:0010307)1.70504486
154Focal segmental glomerulosclerosis (HP:0000097)1.70271875
155Long palpebral fissure (HP:0000637)1.66111042
156Joint stiffness (HP:0001387)1.65746525
157Ankyloglossia (HP:0010296)1.65173459

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.41580095
2MST1R3.91777995
3EPHA23.90854831
4ERN12.96665768
5EEF2K2.65302847
6TGFBR22.47553907
7ZAP702.45781042
8PRPF4B2.38717762
9STK102.37206827
10JAK32.33980508
11TYK22.33940579
12BLK2.28080207
13PKN22.26193568
14KIT2.15809910
15MAP2K32.12451009
16BTK2.02702822
17TRIB31.97954189
18TXK1.97464485
19TBK11.92929985
20LRRK21.91620734
21TEC1.86772812
22KDR1.86181626
23LMTK21.86110039
24MET1.75988590
25SMG11.75729795
26CSF1R1.75600818
27ICK1.71620602
28IKBKE1.67792338
29IRAK41.66877237
30TAOK31.63063069
31MAP3K101.60003549
32FLT31.59680754
33ITK1.55413983
34NME21.51978279
35GRK61.49290376
36EPHB21.47970184
37SYK1.42286528
38TGFBR11.41303462
39JAK11.39352954
40FES1.37044614
41PTK21.36841691
42PRKD21.31121170
43RPS6KA41.29967297
44FGFR41.28829171
45LCK1.26993832
46CSK1.25515036
47HCK1.25140495
48PDGFRA1.24384842
49DDR21.21183131
50MAP3K141.20922133
51IRAK21.20157744
52EPHB11.18951389
53MST41.17400214
54BMX1.16589200
55PAK41.14350223
56CDC42BPA1.10933942
57RPS6KB21.09099753
58RIPK11.08125033
59TTN1.07963750
60IKBKB1.05668136
61PTK61.02348712
62IRAK30.99259525
63MAP3K10.98326374
64LYN0.95339269
65MAP3K30.92952125
66CLK10.92515879
67SCYL20.92417304
68FGR0.92039289
69NLK0.91050738
70MAPKAPK30.88629992
71PIM10.87418804
72TRPM70.83429349
73PIM20.81840177
74MATK0.81284440
75FGFR30.80822219
76IRAK10.79722345
77PDPK10.76992475
78MAP3K110.75843421
79MAP3K130.73100703
80JAK20.72868294
81NEK20.72250353
82MOS0.70667460
83PASK0.69577912
84TESK20.68330351
85TIE10.68306677
86MAP3K80.65581539
87TNK20.65571125
88GRK70.64932957
89KSR20.62630598
90CDK60.59744633
91RPS6KA20.59508212
92CHUK0.59167998
93NEK90.58821902
94CDK40.58574611
95MARK20.58031772
96CAMKK20.58028838
97RIPK40.57537902
98ARAF0.56058105
99ABL20.55536353
100TAOK10.54385972
101SIK30.54341304
102BRSK20.53312726
103MAP3K60.51098870
104RPS6KA60.50772662
105STK40.50753030
106MARK30.50310848
107PRKG20.49914409
108PTK2B0.47599872
109MAP3K70.46828782
110SIK10.45972821
111HIPK20.45095850
112BRAF0.44098419
113MTOR0.43375989
114CAMK1D0.43288057
115NTRK10.42407128
116MYLK0.40435772
117SIK20.40096471
118MAPK110.39964001
119EGFR0.39662661
120MAPKAPK20.39373187
121RPS6KL10.37109902
122RPS6KC10.37109902
123PRKCQ0.36836576
124PDGFRB0.36805941
125ERBB40.36551019
126CDK120.35504626
127PRKCH0.35213949
128TESK10.34689583
129STK380.33932778
130TAOK20.32321234
131ABL10.31587780
132MAPK40.31119869
133PAK10.30886975
134ILK0.30737173
135PIK3CG0.30512114
136DYRK1B0.29979376
137CDK90.29033837
138PDK10.27704154

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.12681336
2Leishmaniasis_Homo sapiens_hsa051402.63431174
3B cell receptor signaling pathway_Homo sapiens_hsa046622.39887707
4Other glycan degradation_Homo sapiens_hsa005112.36831666
5Antigen processing and presentation_Homo sapiens_hsa046122.30056645
6Measles_Homo sapiens_hsa051622.13181769
7Osteoclast differentiation_Homo sapiens_hsa043802.11233421
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.08150684
9Hematopoietic cell lineage_Homo sapiens_hsa046402.07704237
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.99606606
11Glycosaminoglycan degradation_Homo sapiens_hsa005311.98962466
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.90567383
13Staphylococcus aureus infection_Homo sapiens_hsa051501.88811764
14Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.84922300
15Leukocyte transendothelial migration_Homo sapiens_hsa046701.71968731
16Bladder cancer_Homo sapiens_hsa052191.68691651
17Toll-like receptor signaling pathway_Homo sapiens_hsa046201.61794646
18Shigellosis_Homo sapiens_hsa051311.61700223
19Toxoplasmosis_Homo sapiens_hsa051451.60100552
20Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.59490889
21DNA replication_Homo sapiens_hsa030301.58812321
22T cell receptor signaling pathway_Homo sapiens_hsa046601.58099621
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.55648608
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.51756694
25Legionellosis_Homo sapiens_hsa051341.49441252
26Lysosome_Homo sapiens_hsa041421.49288996
27Herpes simplex infection_Homo sapiens_hsa051681.46386326
28Pertussis_Homo sapiens_hsa051331.45660908
29Apoptosis_Homo sapiens_hsa042101.37200347
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.35321173
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.34062716
32Platelet activation_Homo sapiens_hsa046111.32579485
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.30901543
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.30446712
35Ribosome_Homo sapiens_hsa030101.29848397
36Chronic myeloid leukemia_Homo sapiens_hsa052201.28606856
37Acute myeloid leukemia_Homo sapiens_hsa052211.28491229
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27881930
39Tuberculosis_Homo sapiens_hsa051521.27499404
40Malaria_Homo sapiens_hsa051441.27393127
41Influenza A_Homo sapiens_hsa051641.25386820
42Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.24200875
43Hepatitis B_Homo sapiens_hsa051611.21289193
44Viral myocarditis_Homo sapiens_hsa054161.14622526
45Pancreatic cancer_Homo sapiens_hsa052121.13861030
46Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.10615708
47TNF signaling pathway_Homo sapiens_hsa046681.09337944
48NOD-like receptor signaling pathway_Homo sapiens_hsa046211.09212875
49Fructose and mannose metabolism_Homo sapiens_hsa000511.08593862
50Chemokine signaling pathway_Homo sapiens_hsa040621.07448750
51Transcriptional misregulation in cancer_Homo sapiens_hsa052021.07041549
52Caffeine metabolism_Homo sapiens_hsa002321.06479009
53Base excision repair_Homo sapiens_hsa034101.04989628
54African trypanosomiasis_Homo sapiens_hsa051431.00971235
55N-Glycan biosynthesis_Homo sapiens_hsa005101.00223475
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.99842254
57Prion diseases_Homo sapiens_hsa050200.98832947
58Small cell lung cancer_Homo sapiens_hsa052220.98236515
59Salmonella infection_Homo sapiens_hsa051320.97499898
60ECM-receptor interaction_Homo sapiens_hsa045120.96674761
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.95241885
62AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.94923188
63Allograft rejection_Homo sapiens_hsa053300.90949992
64Hepatitis C_Homo sapiens_hsa051600.89711197
65Renal cell carcinoma_Homo sapiens_hsa052110.88892890
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.85784208
67Mismatch repair_Homo sapiens_hsa034300.85780086
68Viral carcinogenesis_Homo sapiens_hsa052030.85037697
69Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83423905
70Asthma_Homo sapiens_hsa053100.83077104
71HTLV-I infection_Homo sapiens_hsa051660.81923831
72Sulfur metabolism_Homo sapiens_hsa009200.80642166
73p53 signaling pathway_Homo sapiens_hsa041150.76212732
74Graft-versus-host disease_Homo sapiens_hsa053320.74376314
75Epstein-Barr virus infection_Homo sapiens_hsa051690.74232193
76Vibrio cholerae infection_Homo sapiens_hsa051100.73911434
77Sulfur relay system_Homo sapiens_hsa041220.71938008
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71697891
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71186438
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69848666
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.67952497
82Adipocytokine signaling pathway_Homo sapiens_hsa049200.67947540
83Pentose phosphate pathway_Homo sapiens_hsa000300.67722184
84VEGF signaling pathway_Homo sapiens_hsa043700.67718979
85Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67401629
86Non-homologous end-joining_Homo sapiens_hsa034500.67395674
87Non-small cell lung cancer_Homo sapiens_hsa052230.64966097
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61279551
89Type I diabetes mellitus_Homo sapiens_hsa049400.60985674
90Complement and coagulation cascades_Homo sapiens_hsa046100.60514235
91GnRH signaling pathway_Homo sapiens_hsa049120.59989030
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.59001159
93Prolactin signaling pathway_Homo sapiens_hsa049170.58847254
94Phospholipase D signaling pathway_Homo sapiens_hsa040720.57628037
95Colorectal cancer_Homo sapiens_hsa052100.57349162
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.57242652
97Sphingolipid metabolism_Homo sapiens_hsa006000.56610128
98Notch signaling pathway_Homo sapiens_hsa043300.55084266
99Insulin signaling pathway_Homo sapiens_hsa049100.53404681
100Phagosome_Homo sapiens_hsa041450.52774042
101Renin-angiotensin system_Homo sapiens_hsa046140.52640015
102Rap1 signaling pathway_Homo sapiens_hsa040150.52109553
103Amoebiasis_Homo sapiens_hsa051460.51981725
104Focal adhesion_Homo sapiens_hsa045100.49985732
105ABC transporters_Homo sapiens_hsa020100.49108536
106Thyroid cancer_Homo sapiens_hsa052160.48191604
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47148967
108Insulin resistance_Homo sapiens_hsa049310.46996631
109Proteoglycans in cancer_Homo sapiens_hsa052050.46745442
110mTOR signaling pathway_Homo sapiens_hsa041500.45797032
111HIF-1 signaling pathway_Homo sapiens_hsa040660.45598793
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45148541
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44493608
114Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44245742
115Endocytosis_Homo sapiens_hsa041440.43956561
116Autoimmune thyroid disease_Homo sapiens_hsa053200.43205344
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.42889099
118Galactose metabolism_Homo sapiens_hsa000520.39500177
119Cell cycle_Homo sapiens_hsa041100.35689640
120Nucleotide excision repair_Homo sapiens_hsa034200.34416434
121Spliceosome_Homo sapiens_hsa030400.34184146
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.33362173
123Rheumatoid arthritis_Homo sapiens_hsa053230.33316452

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