TOR3A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.26574353
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.26574353
3antigen processing and presentation of endogenous antigen (GO:0019883)5.79752331
4positive regulation by symbiont of host defense response (GO:0052509)5.62718311
5modulation by symbiont of host defense response (GO:0052031)5.62718311
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.62718311
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.62718311
8positive regulation by organism of defense response of other organism involved in symbiotic interact5.62718311
9modulation by symbiont of host immune response (GO:0052553)5.62718311
10negative regulation of microtubule polymerization (GO:0031115)5.57241277
11positive regulation of interferon-alpha production (GO:0032727)5.44597783
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.41431158
13regulation of interferon-alpha production (GO:0032647)5.15605254
14cellular response to type I interferon (GO:0071357)5.04667158
15type I interferon signaling pathway (GO:0060337)5.04667158
16response to type I interferon (GO:0034340)5.03437811
17regulation of interferon-beta biosynthetic process (GO:0045357)4.80763825
18immunoglobulin mediated immune response (GO:0016064)4.66769395
19response to interferon-alpha (GO:0035455)4.62891352
20neutrophil activation involved in immune response (GO:0002283)4.40616621
21response to peptidoglycan (GO:0032494)4.32899557
22macrophage activation involved in immune response (GO:0002281)4.17754881
23DNA unwinding involved in DNA replication (GO:0006268)4.08906817
24positive regulation of interferon-beta production (GO:0032728)4.04353180
25DNA strand elongation involved in DNA replication (GO:0006271)3.96452202
26gonadal mesoderm development (GO:0007506)3.92050953
27response to host immune response (GO:0052572)3.91960481
28response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.91960481
29cellular response to interferon-alpha (GO:0035457)3.87255206
30cellular response to interferon-beta (GO:0035458)3.84146816
31DNA strand elongation (GO:0022616)3.83720657
32interferon-gamma-mediated signaling pathway (GO:0060333)3.81406667
33response to interferon-beta (GO:0035456)3.80446577
34positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.76871471
35negative regulation of viral genome replication (GO:0045071)3.76824162
36GDP-mannose metabolic process (GO:0019673)3.73132655
37B cell mediated immunity (GO:0019724)3.67646025
38positive regulation of antigen processing and presentation (GO:0002579)3.62350989
39positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.61901086
40lipopolysaccharide-mediated signaling pathway (GO:0031663)3.61517382
41folic acid metabolic process (GO:0046655)3.60307011
42T-helper 1 type immune response (GO:0042088)3.59334825
43response to host (GO:0075136)3.55546403
44response to host defenses (GO:0052200)3.55546403
45response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.55546403
46cellular response to zinc ion (GO:0071294)3.54648208
47DNA replication initiation (GO:0006270)3.54165237
48positive regulation of gamma-delta T cell activation (GO:0046645)3.52725991
49regulation of type I interferon-mediated signaling pathway (GO:0060338)3.52355111
50respiratory burst (GO:0045730)3.51124902
51positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.40282569
52granulocyte activation (GO:0036230)3.37659861
53positive regulation of chemokine biosynthetic process (GO:0045080)3.35409533
54natural killer cell mediated cytotoxicity (GO:0042267)3.32470193
55natural killer cell mediated immunity (GO:0002228)3.32470193
56deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.31565548
57regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.30082785
58cellular response to virus (GO:0098586)3.29065917
59proline biosynthetic process (GO:0006561)3.27811949
60regulation of RIG-I signaling pathway (GO:0039535)3.27362613
61cellular response to exogenous dsRNA (GO:0071360)3.27345419
62neutrophil activation (GO:0042119)3.25930805
63telomere maintenance via semi-conservative replication (GO:0032201)3.22182451
64regulation of antigen processing and presentation (GO:0002577)3.22144357
65positive regulation of natural killer cell differentiation (GO:0032825)3.21206876
66regulation of dendritic cell antigen processing and presentation (GO:0002604)3.16474051
67snRNA metabolic process (GO:0016073)3.14550322
68NIK/NF-kappaB signaling (GO:0038061)3.14217641
69defense response to protozoan (GO:0042832)3.13070138
70microglial cell activation (GO:0001774)3.12866818
71response to muramyl dipeptide (GO:0032495)3.12807003
72regulation of T-helper 1 cell differentiation (GO:0045625)3.11585214
73cellular response to interferon-gamma (GO:0071346)3.09090636
74mitotic chromosome condensation (GO:0007076)3.06156015
75regulation of interferon-beta production (GO:0032648)3.05404054
76regulation of interleukin-12 biosynthetic process (GO:0045075)3.05162752
77positive regulation of prostaglandin secretion (GO:0032308)3.03984618
78myeloid cell activation involved in immune response (GO:0002275)3.03896282
79positive regulation of interleukin-12 production (GO:0032735)3.01589591
80regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.99040637
81regulation of chemokine biosynthetic process (GO:0045073)2.98325186
82hydrogen peroxide biosynthetic process (GO:0050665)2.96625573
83JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.96179623
84negative regulation of myeloid cell apoptotic process (GO:0033033)2.95019593
85snRNA processing (GO:0016180)2.94512817
86regulation of B cell receptor signaling pathway (GO:0050855)2.94490927
87Golgi transport vesicle coating (GO:0048200)2.94154521
88COPI coating of Golgi vesicle (GO:0048205)2.94154521
89antigen processing and presentation via MHC class Ib (GO:0002475)2.93437416
90defense response to virus (GO:0051607)2.92910254
91positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.89205591
92regulation of interferon-gamma biosynthetic process (GO:0045072)2.88898944
93reactive oxygen species biosynthetic process (GO:1903409)2.88025498
94response to interferon-gamma (GO:0034341)2.83808714
95myeloid dendritic cell differentiation (GO:0043011)2.83380443
96positive regulation of protein homooligomerization (GO:0032464)2.82616198
97detection of molecule of bacterial origin (GO:0032490)2.81850969
98macrophage activation (GO:0042116)2.79595484
99Arp2/3 complex-mediated actin nucleation (GO:0034314)2.78775208
100telomere maintenance via recombination (GO:0000722)2.76727071
101response to protozoan (GO:0001562)2.75921230
102leukocyte mediated cytotoxicity (GO:0001909)2.71642617
103I-kappaB phosphorylation (GO:0007252)2.69059212
104negative regulation of interleukin-17 production (GO:0032700)2.69038656
105myeloid dendritic cell activation (GO:0001773)2.68591133
106dendritic cell differentiation (GO:0097028)2.67431567
107folic acid-containing compound biosynthetic process (GO:0009396)2.67300010
108modulation of growth of symbiont involved in interaction with host (GO:0044144)2.66498152
109regulation of growth of symbiont in host (GO:0044126)2.66498152
110negative regulation of growth of symbiont in host (GO:0044130)2.66498152
111negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.66498152
112regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.64232205
113positive regulation of toll-like receptor signaling pathway (GO:0034123)2.64178418
114positive regulation of B cell differentiation (GO:0045579)2.63436020
115pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.62579726
116regulation of translational fidelity (GO:0006450)2.62355766
117regulation of response to interferon-gamma (GO:0060330)2.62251100
118pinocytosis (GO:0006907)2.62099523
119regulation of interleukin-8 biosynthetic process (GO:0045414)2.61943445
120positive regulation of NF-kappaB import into nucleus (GO:0042346)2.61134130
121regulation of interleukin-12 production (GO:0032655)2.60474864
122T cell migration (GO:0072678)2.59395129
123positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.59005123
124N-acetylneuraminate metabolic process (GO:0006054)2.56256671
125B cell receptor signaling pathway (GO:0050853)2.55816450
126glycosphingolipid catabolic process (GO:0046479)2.52800027
127tRNA methylation (GO:0030488)2.52227790
128pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.52063674
129mitochondrial fusion (GO:0008053)2.48724856
130regulation of mitochondrial translation (GO:0070129)2.48288722
131regulation of prostaglandin secretion (GO:0032306)2.47375812
132mitotic recombination (GO:0006312)2.46286840
133germinal center formation (GO:0002467)2.44597793
134mannose metabolic process (GO:0006013)2.42645960
135pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.41513556
136ceramide catabolic process (GO:0046514)2.41420731
137urea cycle (GO:0000050)2.41027909
138positive regulation of Cdc42 GTPase activity (GO:0043089)2.39886374
139* chaperone mediated protein folding requiring cofactor (GO:0051085)2.38569890
140ribosome biogenesis (GO:0042254)2.38533797
141amyloid precursor protein catabolic process (GO:0042987)2.38029334
142pseudouridine synthesis (GO:0001522)2.35874359
143citrulline biosynthetic process (GO:0019240)2.33328931
144formation of translation preinitiation complex (GO:0001731)2.32828284
145glycolipid catabolic process (GO:0019377)2.31981534
146negative regulation of B cell apoptotic process (GO:0002903)2.31199995
147regulation of chromatin binding (GO:0035561)2.30005860
148negative regulation of erythrocyte differentiation (GO:0045647)2.28927992
149regulation of protein heterodimerization activity (GO:0043497)2.27852081
150nucleotide-excision repair, DNA gap filling (GO:0006297)2.27441788
151regulation of translation in response to stress (GO:0043555)2.26272492
152carnitine shuttle (GO:0006853)2.26184252
153DNA duplex unwinding (GO:0032508)2.25932034
154negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.25087736
155nucleobase biosynthetic process (GO:0046112)2.21677814
156B cell homeostasis (GO:0001782)2.20045438
157nuclear pore complex assembly (GO:0051292)2.18990931
158T cell apoptotic process (GO:0070231)2.17801824
159negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.17581911
160myeloid cell homeostasis (GO:0002262)2.17521154
1613-UTR-mediated mRNA stabilization (GO:0070935)2.16511228
162regulation of histone H3-K27 methylation (GO:0061085)2.15304094
163nitric oxide biosynthetic process (GO:0006809)2.15218832
164DNA geometric change (GO:0032392)2.13609365
165spliceosomal tri-snRNP complex assembly (GO:0000244)2.13607813
166pyrimidine nucleoside salvage (GO:0043097)2.13067109
167pyrimidine-containing compound salvage (GO:0008655)2.13067109
168regulation of B cell apoptotic process (GO:0002902)2.11867455
169rRNA modification (GO:0000154)2.11325112
170dosage compensation (GO:0007549)2.11232880
171tRNA modification (GO:0006400)2.10668517
172base-excision repair (GO:0006284)2.10565656
173pentose-phosphate shunt (GO:0006098)2.10280664
174urea metabolic process (GO:0019627)2.09996140
175positive regulation of protein oligomerization (GO:0032461)2.09086680
176mitotic nuclear envelope disassembly (GO:0007077)2.08241337
177folic acid-containing compound metabolic process (GO:0006760)2.07807843
178DNA replication checkpoint (GO:0000076)2.07343291
179cellular response to arsenic-containing substance (GO:0071243)2.06558007
180deoxyribonucleotide catabolic process (GO:0009264)2.06419601
181pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.05338298
182activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.04160819
183pentose metabolic process (GO:0019321)2.03723593

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.91830634
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.81867650
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.68678242
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.37040325
5IRF8_27001747_Chip-Seq_BMDM_Mouse3.56784753
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.54445750
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.44935508
8SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.12566234
9* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.10489302
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.91108563
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.82985428
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.71295205
13MYB_21317192_ChIP-Seq_ERMYB_Mouse2.67232236
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.59443332
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.55187610
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.47342821
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.47033235
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.27258687
19MYC_18555785_ChIP-Seq_MESCs_Mouse2.21214853
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.18968289
21GATA1_22025678_ChIP-Seq_K562_Human2.18831491
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.16650300
23E2F7_22180533_ChIP-Seq_HELA_Human2.12584262
24SPI1_23547873_ChIP-Seq_NB4_Human2.07809843
25Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.05762453
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.04373760
27MYC_18358816_ChIP-ChIP_MESCs_Mouse2.00166105
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.96620863
29* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.94521292
30FOXM1_23109430_ChIP-Seq_U2OS_Human1.91723183
31STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.89103060
32CIITA_25753668_ChIP-Seq_RAJI_Human1.88866474
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84025361
34DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.83390484
35MYB_26560356_Chip-Seq_TH2_Human1.82565547
36VDR_21846776_ChIP-Seq_THP-1_Human1.79384852
37* MAF_26560356_Chip-Seq_TH1_Human1.77710221
38NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.76320572
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.75832055
40FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.68845568
41TP63_17297297_ChIP-ChIP_HaCaT_Human1.67715393
42ZNF263_19887448_ChIP-Seq_K562_Human1.66685687
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.65844813
44VDR_24763502_ChIP-Seq_THP-1_Human1.64633127
45* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.64547043
46DCP1A_22483619_ChIP-Seq_HELA_Human1.63135657
47RUNX1_22412390_ChIP-Seq_EML_Mouse1.60216584
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.60166494
49XRN2_22483619_ChIP-Seq_HELA_Human1.59520546
50MYC_22102868_ChIP-Seq_BL_Human1.59035421
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.54820984
52CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.53494029
53* MYB_26560356_Chip-Seq_TH1_Human1.53204904
54ETS1_20019798_ChIP-Seq_JURKAT_Human1.52883355
55GABP_19822575_ChIP-Seq_HepG2_Human1.51447512
56NELFA_20434984_ChIP-Seq_ESCs_Mouse1.48524707
57SPI1_23127762_ChIP-Seq_K562_Human1.48460188
58* KDM5A_27292631_Chip-Seq_BREAST_Human1.46991787
59CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.44887061
60E2F4_17652178_ChIP-ChIP_JURKAT_Human1.44122531
61E2F1_21310950_ChIP-Seq_MCF-7_Human1.43936529
62* RACK7_27058665_Chip-Seq_MCF-7_Human1.42235717
63MYC_19079543_ChIP-ChIP_MESCs_Mouse1.41455678
64* PU_27001747_Chip-Seq_BMDM_Mouse1.41445696
65CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.39308172
66PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38420047
67KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.38256987
68P68_20966046_ChIP-Seq_HELA_Human1.37625473
69SCL_19346495_ChIP-Seq_HPC-7_Human1.35579818
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.35051960
71* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33549101
72UTX_26944678_Chip-Seq_JUKART_Human1.31635340
73FOXP3_21729870_ChIP-Seq_TREG_Human1.31365209
74THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30987871
75* TFEB_21752829_ChIP-Seq_HELA_Human1.30668940
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.30046546
77FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.28849155
78EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.28725360
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28711482
80E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28482030
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25026831
82* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.23013790
83SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.23008862
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22633906
85YY1_21170310_ChIP-Seq_MESCs_Mouse1.22592196
86SRF_21415370_ChIP-Seq_HL-1_Mouse1.21939638
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.21581511
88CREB1_15753290_ChIP-ChIP_HEK293T_Human1.21431567
89* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21170909
90* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.21082868
91PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.20856921
92HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.20665499
93* NCOR1_26117541_ChIP-Seq_K562_Human1.20471925
94THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.19790355
95* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.19301662
96BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16739113
97CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.16424282
98BCOR_27268052_Chip-Seq_Bcells_Human1.15165061
99MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15095835
100GATA3_27048872_Chip-Seq_THYMUS_Human1.14749899
101MYCN_18555785_ChIP-Seq_MESCs_Mouse1.14499227
102POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.14174249
103BCL6_27268052_Chip-Seq_Bcells_Human1.13708735
104ELF1_20517297_ChIP-Seq_JURKAT_Human1.13512371
105TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10282838
106* TET1_21451524_ChIP-Seq_MESCs_Mouse1.09586426
107CTCF_26484167_Chip-Seq_Bcells_Mouse1.09300512
108CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08913999
109VDR_23849224_ChIP-Seq_CD4+_Human1.08506612
110PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08382930
111TCF7_22412390_ChIP-Seq_EML_Mouse1.08253557
112RARG_19884340_ChIP-ChIP_MEFs_Mouse1.07693945
113CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07521870
114GATA2_21666600_ChIP-Seq_HMVEC_Human1.07467312
115KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07063177
116RUNX_20019798_ChIP-Seq_JUKART_Human1.06916661
117GATA3_26560356_Chip-Seq_TH2_Human1.04882749
118* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.03648945
119MAF_26560356_Chip-Seq_TH2_Human1.02998690
120PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02686445
121CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01463094
122CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.01320306
123RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99134150
124SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98883862
125LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97548359
126ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.96970486
127ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94787014
128GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91894011
129GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.89688308
130TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87489390
131STAT3_1855785_ChIP-Seq_MESCs_Mouse0.86682872
132PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86381484
133TRIM28_21343339_ChIP-Seq_HEK293_Human0.84916841
134TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.83910177
135NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.82993738
136NOTCH1_21737748_ChIP-Seq_TLL_Human0.82787445
137* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.81975313
138PU.1_20513432_ChIP-Seq_Bcells_Mouse0.80530314
139SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.79329217
140* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.79243731
141PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.78370840
142VDR_24787735_ChIP-Seq_THP-1_Human0.77955975
143* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.77234172
144KDM2B_26808549_Chip-Seq_DND41_Human0.76400612
145HOXB4_20404135_ChIP-ChIP_EML_Mouse0.76168061
146* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.75268765
147SOX2_20726797_ChIP-Seq_SW620_Human0.75078448
148* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.74912928
149* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.74912928
150ELF1_17652178_ChIP-ChIP_JURKAT_Human0.73777516
151* LXR_22292898_ChIP-Seq_THP-1_Human0.73652279
152CLOCK_20551151_ChIP-Seq_293T_Human0.73469059
153FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.72683059

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.27987979
2MP0009785_altered_susceptibility_to3.55299822
3MP0003436_decreased_susceptibility_to3.19881994
4MP0003303_peritoneal_inflammation3.01707382
5MP0005451_abnormal_body_composition2.88623116
6MP0002148_abnormal_hypersensitivity_rea2.84026924
7MP0000685_abnormal_immune_system2.82529467
8MP0003724_increased_susceptibility_to2.79428582
9MP0005058_abnormal_lysosome_morphology2.78889161
10MP0005387_immune_system_phenotype2.78681483
11MP0001790_abnormal_immune_system2.78681483
12MP0005025_abnormal_response_to2.74725043
13MP0005000_abnormal_immune_tolerance2.73734389
14MP0002419_abnormal_innate_immunity2.67000401
15MP0006082_CNS_inflammation2.64805880
16MP0010094_abnormal_chromosome_stability2.64079498
17MP0008057_abnormal_DNA_replication2.46236014
18MP0002452_abnormal_antigen_presenting2.44972796
19MP0001800_abnormal_humoral_immune2.39414004
20MP0005671_abnormal_response_to2.37351225
21MP0002723_abnormal_immune_serum2.29956613
22MP0003111_abnormal_nucleus_morphology2.23164321
23MP0003693_abnormal_embryo_hatching2.20320599
24MP0001661_extended_life_span2.09931923
25MP0001819_abnormal_immune_cell2.06592386
26MP0004510_myositis2.04510496
27MP0001533_abnormal_skeleton_physiology2.04178459
28MP0002420_abnormal_adaptive_immunity2.03826404
29MP0003172_abnormal_lysosome_physiology2.01379694
30MP0003806_abnormal_nucleotide_metabolis1.94105942
31MP0008438_abnormal_cutaneous_collagen1.92642068
32MP0003300_gastrointestinal_ulcer1.92011232
33MP0004947_skin_inflammation1.89705954
34MP0002166_altered_tumor_susceptibility1.86730742
35MP0003077_abnormal_cell_cycle1.83673251
36MP0002006_tumorigenesis1.77317738
37MP0005464_abnormal_platelet_physiology1.76866050
38MP0001845_abnormal_inflammatory_respons1.73219723
39MP0001853_heart_inflammation1.70672281
40MP0003448_altered_tumor_morphology1.70576076
41MP0008058_abnormal_DNA_repair1.70092960
42MP0010155_abnormal_intestine_physiology1.67270046
43MP0003191_abnormal_cellular_cholesterol1.66757608
44MP0009840_abnormal_foam_cell1.63801316
45MP0002405_respiratory_system_inflammati1.62649081
46MP0008469_abnormal_protein_level1.59778689
47MP0000858_altered_metastatic_potential1.58520531
48MP0002009_preneoplasia1.58261777
49MP0000716_abnormal_immune_system1.58032556
50MP0000343_altered_response_to1.57143407
51MP0002398_abnormal_bone_marrow1.53577082
52MP0009764_decreased_sensitivity_to1.52447822
53MP0004233_abnormal_muscle_weight1.49055792
54MP0010307_abnormal_tumor_latency1.45692124
55MP0009333_abnormal_splenocyte_physiolog1.45140010
56MP0003566_abnormal_cell_adhesion1.44007384
57MP0004957_abnormal_blastocyst_morpholog1.39868120
58MP0005083_abnormal_biliary_tract1.38228994
59MP0009278_abnormal_bone_marrow1.36738935
60MP0005310_abnormal_salivary_gland1.35426560
61MP0003786_premature_aging1.34781074
62MP0003075_altered_response_to1.32858651
63MP0002429_abnormal_blood_cell1.32173970
64MP0003221_abnormal_cardiomyocyte_apopto1.31471747
65MP0001958_emphysema1.31443559
66MP0010234_abnormal_vibrissa_follicle1.30938970
67MP0000689_abnormal_spleen_morphology1.30792983
68MP0006054_spinal_hemorrhage1.28349259
69MP0002998_abnormal_bone_remodeling1.28187370
70MP0010352_gastrointestinal_tract_polyps1.26992199
71MP0005397_hematopoietic_system_phenotyp1.25559122
72MP0001545_abnormal_hematopoietic_system1.25559122
73MP0002139_abnormal_hepatobiliary_system1.25550559
74MP0000747_muscle_weakness1.24692656
75MP0009697_abnormal_copulation1.23297786
76MP0002722_abnormal_immune_system1.21675718
77MP0003705_abnormal_hypodermis_morpholog1.20256271
78MP0002163_abnormal_gland_morphology1.18878720
79MP0004185_abnormal_adipocyte_glucose1.18581734
80MP0008007_abnormal_cellular_replicative1.17095353
81MP0004264_abnormal_extraembryonic_tissu1.16492348
82MP0002933_joint_inflammation1.14828614
83MP0000313_abnormal_cell_death1.13746220
84MP0003656_abnormal_erythrocyte_physiolo1.11146061
85MP0005076_abnormal_cell_differentiation1.09664385
86MP0008260_abnormal_autophagy1.09242003
87MP0005023_abnormal_wound_healing1.08611186
88MP0003763_abnormal_thymus_physiology1.08062533
89MP0005390_skeleton_phenotype1.07703721
90MP0004808_abnormal_hematopoietic_stem1.06411384
91MP0003183_abnormal_peptide_metabolism1.03885279
92MP0006036_abnormal_mitochondrial_physio1.02864031
93MP0002254_reproductive_system_inflammat1.02329857
94MP0004782_abnormal_surfactant_physiolog1.00404445
95MP0002877_abnormal_melanocyte_morpholog0.98045730
96MP0000350_abnormal_cell_proliferation0.97774012
97MP0003186_abnormal_redox_activity0.97270072
98MP0003091_abnormal_cell_migration0.97213721
99MP0000604_amyloidosis0.96650341
100MP0000490_abnormal_crypts_of0.96648961
101MP0005164_abnormal_response_to0.96002343
102MP0002138_abnormal_hepatobiliary_system0.95034458
103MP0001873_stomach_inflammation0.94352458
104MP0002396_abnormal_hematopoietic_system0.93529530
105MP0005166_decreased_susceptibility_to0.92615722
106MP0000358_abnormal_cell_content/0.92489501
107MP0005257_abnormal_intraocular_pressure0.92327270
108MP0005330_cardiomyopathy0.90734819
109MP0009763_increased_sensitivity_to0.90535466
110MP0005584_abnormal_enzyme/coenzyme_acti0.90035704
111MP0008932_abnormal_embryonic_tissue0.89828225
112MP0001730_embryonic_growth_arrest0.88639813
113MP0000609_abnormal_liver_physiology0.86770038
114MP0006035_abnormal_mitochondrial_morpho0.85733878
115MP0000465_gastrointestinal_hemorrhage0.82581716
116MP0001851_eye_inflammation0.81930041
117MP0000249_abnormal_blood_vessel0.81364225
118MP0003279_aneurysm0.80973485
119MP0005275_abnormal_skin_tensile0.79856984
120MP0003795_abnormal_bone_structure0.79080403
121MP0009643_abnormal_urine_homeostasis0.78112250
122MP0005319_abnormal_enzyme/_coenzyme0.77009774
123MP0005501_abnormal_skin_physiology0.75187845
124MP0003828_pulmonary_edema0.75097762
125MP0004858_abnormal_nervous_system0.75092197
126MP0003453_abnormal_keratinocyte_physiol0.74965233
127MP0005167_abnormal_blood-brain_barrier0.74396756
128MP0000750_abnormal_muscle_regeneration0.73833996
129MP0003646_muscle_fatigue0.73476214
130MP0001727_abnormal_embryo_implantation0.73475372
131MP0002136_abnormal_kidney_physiology0.70668268
132MP0001879_abnormal_lymphatic_vessel0.70099574
133MP0000703_abnormal_thymus_morphology0.69095982
134MP0003045_fibrosis0.69089433
135MP0000767_abnormal_smooth_muscle0.67502400
136MP0005174_abnormal_tail_pigmentation0.66240183
137MP0002019_abnormal_tumor_incidence0.65953700
138MP0002693_abnormal_pancreas_physiology0.65543591
139MP0000371_diluted_coat_color0.65061106
140MP0003866_abnormal_defecation0.64495904
141MP0002277_abnormal_respiratory_mucosa0.63663892

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.59934709
2Eczematoid dermatitis (HP:0000976)5.50548300
3Recurrent bacterial skin infections (HP:0005406)5.02734677
4Elevated erythrocyte sedimentation rate (HP:0003565)4.80643953
5Chronic otitis media (HP:0000389)4.44999522
6Abnormality of macrophages (HP:0004311)4.39318461
7Vacuolated lymphocytes (HP:0001922)4.23454149
8Autoimmune thrombocytopenia (HP:0001973)4.15736947
9Recurrent gram-negative bacterial infections (HP:0005420)4.06333014
10Increased cerebral lipofuscin (HP:0011813)3.99575389
11Myositis (HP:0100614)3.95292790
12Agammaglobulinemia (HP:0004432)3.90673241
13Ragged-red muscle fibers (HP:0003200)3.75489048
14Mediastinal lymphadenopathy (HP:0100721)3.73444343
15Interstitial pulmonary disease (HP:0006530)3.71948334
16Increased neuronal autofluorescent lipopigment (HP:0002074)3.59238190
17Systemic lupus erythematosus (HP:0002725)3.47745981
18Basal ganglia calcification (HP:0002135)3.44561586
19Progressive muscle weakness (HP:0003323)3.42852334
20Orchitis (HP:0100796)3.40594321
21Abnormality of the nasal mucosa (HP:0000433)3.37733488
22Nasal polyposis (HP:0100582)3.35049873
23Dysostosis multiplex (HP:0000943)3.34423516
24Recurrent viral infections (HP:0004429)3.33512977
25Recurrent skin infections (HP:0001581)3.26866226
26Recurrent fungal infections (HP:0002841)3.18984919
27Vasculitis (HP:0002633)3.17854902
28Gingivitis (HP:0000230)3.14805290
29Chromosomal breakage induced by crosslinking agents (HP:0003221)3.12189837
30Urinary glycosaminoglycan excretion (HP:0003541)3.10555039
31Mucopolysacchariduria (HP:0008155)3.10555039
32Recurrent bronchitis (HP:0002837)3.06389653
33Microvesicular hepatic steatosis (HP:0001414)3.05033412
34Cellulitis (HP:0100658)2.97706677
35Hematochezia (HP:0002573)2.97082636
36Chromsome breakage (HP:0040012)2.94681812
37Abnormality of polysaccharide metabolism (HP:0011012)2.83830281
38Abnormality of glycosaminoglycan metabolism (HP:0004371)2.83830281
39Abnormality of mucopolysaccharide metabolism (HP:0011020)2.83830281
40Abnormality of liposaccharide metabolism (HP:0010968)2.76320417
41Abnormality of glycosphingolipid metabolism (HP:0004343)2.76320417
42Abnormality of glycolipid metabolism (HP:0010969)2.76320417
43Tetraparesis (HP:0002273)2.76090996
44Hypergammaglobulinemia (HP:0010702)2.72507632
45Chronic obstructive pulmonary disease (HP:0006510)2.69901533
46Obstructive lung disease (HP:0006536)2.69901533
47Thrombocytosis (HP:0001894)2.67527522
48Increased IgM level (HP:0003496)2.67260416
49Cervical subluxation (HP:0003308)2.67208098
50Retrobulbar optic neuritis (HP:0100654)2.66828077
51Optic neuritis (HP:0100653)2.66828077
52Abnormality of pyrimidine metabolism (HP:0004353)2.66434804
53Emphysema (HP:0002097)2.65391015
54Stomatitis (HP:0010280)2.65043291
55Type I transferrin isoform profile (HP:0003642)2.64417062
56Myoglobinuria (HP:0002913)2.61231119
57Poikiloderma (HP:0001029)2.59045606
58Vertebral compression fractures (HP:0002953)2.57548744
59Reduced antithrombin III activity (HP:0001976)2.55501274
60Pustule (HP:0200039)2.54417981
61Periodontitis (HP:0000704)2.51548543
62Neoplasm of head and neck (HP:0012288)2.50089734
63Esophageal neoplasm (HP:0100751)2.50089734
64Chronic sinusitis (HP:0011109)2.48643731
65Pulmonary infiltrates (HP:0002113)2.47496337
66Loss of speech (HP:0002371)2.44050532
67Chronic mucocutaneous candidiasis (HP:0002728)2.43770583
68Recurrent cutaneous fungal infections (HP:0011370)2.43770583
69Rhabdomyolysis (HP:0003201)2.43095163
70Osteomyelitis (HP:0002754)2.41985494
71Testicular atrophy (HP:0000029)2.39759392
72Hyperammonemia (HP:0001987)2.38804068
73Abnormal protein glycosylation (HP:0012346)2.38192460
74Abnormal glycosylation (HP:0012345)2.38192460
75Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.38192460
76Abnormal protein N-linked glycosylation (HP:0012347)2.38192460
77Osteolytic defects of the hand bones (HP:0009699)2.37424713
78Osteolytic defects of the phalanges of the hand (HP:0009771)2.37424713
79Thoracic kyphosis (HP:0002942)2.36764525
80Hypokinesia (HP:0002375)2.35048872
81Disinhibition (HP:0000734)2.33310019
82Axonal loss (HP:0003447)2.32707452
83Poor head control (HP:0002421)2.32506228
84Hypertensive crisis (HP:0100735)2.31861635
85Urticaria (HP:0001025)2.27268941
86Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.25271851
87Villous atrophy (HP:0011473)2.25094207
88Abnormality of small intestinal villus morphology (HP:0011472)2.25094207
89Abnormality of the thoracic spine (HP:0100711)2.24128734
90Petechiae (HP:0000967)2.23224962
91Gastrointestinal infarctions (HP:0005244)2.22462199
92Colitis (HP:0002583)2.21895668
93Abnormal delayed hypersensitivity skin test (HP:0002963)2.21861404
94Squamous cell carcinoma (HP:0002860)2.21713969
95Arterial thrombosis (HP:0004420)2.20960503
96Hemoptysis (HP:0002105)2.18581199
97Meningitis (HP:0001287)2.17471341
98Spontaneous hematomas (HP:0007420)2.16224836
99Peritonitis (HP:0002586)2.15585049
100Recurrent lower respiratory tract infections (HP:0002783)2.15036400
101IgA deficiency (HP:0002720)2.14008758
102Panhypogammaglobulinemia (HP:0003139)2.13300290
103Increased IgE level (HP:0003212)2.13114532
104Recurrent pneumonia (HP:0006532)2.12740870
105Abnormality of T cell physiology (HP:0011840)2.12171193
106Myopathic facies (HP:0002058)2.10878630
107Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.09549879
108Myocardial infarction (HP:0001658)2.09492898
109Skin ulcer (HP:0200042)2.08100110
110Leukocytosis (HP:0001974)2.07904632
111Fatigue (HP:0012378)2.07027161
112Cholecystitis (HP:0001082)2.06678460
113Abnormal gallbladder physiology (HP:0012438)2.06678460
114Progressive external ophthalmoplegia (HP:0000590)2.06514985
115Porencephaly (HP:0002132)2.05888177
116Inflammation of the large intestine (HP:0002037)2.05587737
117Glomerulonephritis (HP:0000099)2.04393057
118Exercise-induced myalgia (HP:0003738)2.04056319
119Gastrointestinal stroma tumor (HP:0100723)2.03848445
120Gastrointestinal inflammation (HP:0004386)2.03359006
121Premature loss of primary teeth (HP:0006323)2.03284227
122Hepatosplenomegaly (HP:0001433)2.02632678
123Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.02061115
124Increased serum ferritin (HP:0003281)2.01656715
125Leukopenia (HP:0001882)2.00848573
126Gingival bleeding (HP:0000225)2.00523067
127Cheilitis (HP:0100825)1.99068237
128Autoimmune hemolytic anemia (HP:0001890)1.98483838
129Recurrent sinusitis (HP:0011108)1.98447383
130Multiple enchondromatosis (HP:0005701)1.98231270
131Abnormality of the pericardium (HP:0001697)1.95355901
132Chest pain (HP:0100749)1.94738498
133Chronic diarrhea (HP:0002028)1.94625401
134Abnormality of cells of the lymphoid lineage (HP:0012140)1.94357368
135Abnormality of the vasculature of the conjunctiva (HP:0008054)1.94178038
136Restrictive lung disease (HP:0002091)1.93858923
137Paralysis (HP:0003470)1.92593345
138Abnormality of T cells (HP:0002843)1.92344733
139Lymphopenia (HP:0001888)1.92050029
140Agnosia (HP:0010524)1.90923522
141Rough bone trabeculation (HP:0100670)1.89832919
142Nephritis (HP:0000123)1.89668491
143Eosinophilia (HP:0001880)1.89025654
144Hemorrhage of the eye (HP:0011885)1.87469151
145Malnutrition (HP:0004395)1.86932260
146Cardiomegaly (HP:0001640)1.86931901
147Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.86858191
148Thick nail (HP:0001805)1.86820402
149Alkalosis (HP:0001948)1.86134686
150Viral hepatitis (HP:0006562)1.85138383
151J-shaped sella turcica (HP:0002680)1.82666517
152Entropion (HP:0000621)1.82154475
153Skin rash (HP:0000988)1.82129307
154Bone pain (HP:0002653)1.81579180
155Hypergonadotropic hypogonadism (HP:0000815)1.80242753
156Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.78274125
157Lymphoma (HP:0002665)1.76949318
158IgM deficiency (HP:0002850)1.74510394

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TYK23.66673374
2TBK13.64626688
3ERN13.64588662
4MAP3K142.97950711
5PDK22.95625359
6SMG12.92742736
7BLK2.92481596
8JAK32.88803990
9KIT2.79398188
10IKBKE2.77063956
11MAP4K12.71886127
12IRAK42.55663896
13IRAK32.54620469
14JAK12.39271965
15PRPF4B2.38217933
16PIM22.32372712
17RIPK42.04991760
18IKBKB2.00376195
19MAPKAPK31.86522422
20RPS6KA41.85185952
21FGFR41.83863028
22TGFBR21.79797035
23RPS6KB21.71142670
24MAP2K71.69613561
25ZAP701.66911100
26CDC71.66664361
27TESK21.65442891
28NME21.60983438
29TRIB31.58933263
30STK101.57446808
31WNK41.56925587
32EPHB11.46733123
33PBK1.46253941
34CSF1R1.43735595
35CSK1.40095253
36BTK1.36777541
37TAOK31.34976430
38LRRK21.32369944
39KDR1.31785036
40MAP3K131.31505989
41MAP2K21.30880592
42MST1R1.29106633
43FLT31.28969112
44NEK91.28287358
45SYK1.26551606
46CHUK1.25345354
47TXK1.21896606
48FGFR31.18753950
49SCYL21.16557103
50HCK1.13187145
51VRK21.09800159
52EPHA31.08359233
53PKN21.07601568
54MATK1.07394444
55TEC1.07147053
56BCKDK1.06388180
57MAP3K101.06355496
58CHEK21.02719218
59ZAK1.02213743
60PTK61.01780060
61JAK21.00568078
62TTN0.98997407
63MAP2K30.98271323
64STK390.98177102
65PIM10.98077642
66LYN0.97666045
67CDK70.97299494
68LCK0.95212872
69TAOK20.84257372
70RIPK10.83521002
71MAP3K40.81630389
72PDPK10.81045890
73BUB10.78818959
74TLK10.78600233
75PAK40.78490008
76AURKA0.78299030
77ICK0.77230709
78ARAF0.76706111
79MARK30.74894307
80BMX0.74455518
81MAPK120.73559096
82ATR0.72036346
83ABL20.71770655
84EIF2AK20.70690731
85IRAK10.69442000
86TESK10.68840003
87MOS0.68645452
88MAP3K30.67757049
89OXSR10.65715407
90MST40.64135225
91FES0.62757081
92CDK80.62601128
93MAP3K50.61191292
94TGFBR10.61164083
95MAP2K40.61155205
96TTK0.59467471
97IRAK20.58647598
98MELK0.58130294
99CCNB10.58001440
100ITK0.57678438
101MAPKAPK50.57175588
102NEK60.56772986
103STK40.56094018
104SIK20.55692056
105EGFR0.55536759
106PRKCI0.54859585
107BRAF0.54394183
108STK30.54281808
109MTOR0.54200681
110HIPK20.53779952
111CDK90.53752482
112PRKCD0.53547067
113AURKB0.52920722
114MAP3K80.52516798
115ABL10.51438031
116NME10.51196375
117PDK10.50885802
118NLK0.50702538
119SIK30.48282051
120FGR0.48087692
121EPHA20.47553789
122CHEK10.46278872
123RPS6KA20.45983529
124MAPK70.44857179
125SRPK10.43514773
126EIF2AK30.43060246
127TRPM70.42200464
128GRK60.41443854
129MAP3K110.41235811
130CDK60.39509418
131MAPKAPK20.39021331
132PRKG20.37888341
133MAP3K10.37772044
134CAMK1D0.37326010
135CDK120.37050241
136CDK40.37016411
137SIK10.36220303
138EIF2AK10.34916199
139RPS6KA60.34648235
140RPS6KA50.33544847
141PASK0.31515525
142MAPK110.30858259
143CAMKK20.29434612
144DAPK30.28785925
145ALK0.28250309
146EEF2K0.27611229
147PDGFRA0.26651143
148PIK3CG0.25175990
149TIE10.24982267

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.16195236
2Toll-like receptor signaling pathway_Homo sapiens_hsa046202.80448100
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.75363262
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.55563575
5Sulfur relay system_Homo sapiens_hsa041222.53841229
6RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.47378927
7Measles_Homo sapiens_hsa051622.38708431
8Legionellosis_Homo sapiens_hsa051342.30373976
9Antigen processing and presentation_Homo sapiens_hsa046122.29683904
10Osteoclast differentiation_Homo sapiens_hsa043802.17407488
11Malaria_Homo sapiens_hsa051442.14125429
12Allograft rejection_Homo sapiens_hsa053302.13247269
13Pertussis_Homo sapiens_hsa051332.11636686
14Lysosome_Homo sapiens_hsa041422.11530047
15Staphylococcus aureus infection_Homo sapiens_hsa051502.09401742
16Glycosaminoglycan degradation_Homo sapiens_hsa005312.08535567
17Influenza A_Homo sapiens_hsa051642.05234188
18Graft-versus-host disease_Homo sapiens_hsa053321.94947665
19Herpes simplex infection_Homo sapiens_hsa051681.92086304
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.91784273
21Tuberculosis_Homo sapiens_hsa051521.90275978
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89862501
23Fructose and mannose metabolism_Homo sapiens_hsa000511.89754396
24Other glycan degradation_Homo sapiens_hsa005111.89451667
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.84478585
26TNF signaling pathway_Homo sapiens_hsa046681.79620520
27Non-homologous end-joining_Homo sapiens_hsa034501.79034322
28Toxoplasmosis_Homo sapiens_hsa051451.77164589
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.75809409
30Mismatch repair_Homo sapiens_hsa034301.74131701
31B cell receptor signaling pathway_Homo sapiens_hsa046621.67006735
32Apoptosis_Homo sapiens_hsa042101.55610665
33Homologous recombination_Homo sapiens_hsa034401.50303893
34Primary immunodeficiency_Homo sapiens_hsa053401.49995778
35Pyrimidine metabolism_Homo sapiens_hsa002401.48741402
36Rheumatoid arthritis_Homo sapiens_hsa053231.45895684
37Type I diabetes mellitus_Homo sapiens_hsa049401.44947519
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.40921615
39Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.40264210
40Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.40205929
41Asthma_Homo sapiens_hsa053101.37144911
42Biosynthesis of amino acids_Homo sapiens_hsa012301.36968513
43Jak-STAT signaling pathway_Homo sapiens_hsa046301.35481300
44Nucleotide excision repair_Homo sapiens_hsa034201.32867093
45Phagosome_Homo sapiens_hsa041451.31970425
46Salmonella infection_Homo sapiens_hsa051321.30680070
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.28483466
48Hepatitis C_Homo sapiens_hsa051601.27606226
49Hepatitis B_Homo sapiens_hsa051611.27087908
50Systemic lupus erythematosus_Homo sapiens_hsa053221.27021883
51African trypanosomiasis_Homo sapiens_hsa051431.26992410
52Shigellosis_Homo sapiens_hsa051311.26465493
53Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.25966020
54Hematopoietic cell lineage_Homo sapiens_hsa046401.25366556
55Cell cycle_Homo sapiens_hsa041101.21110108
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.20285702
57Fanconi anemia pathway_Homo sapiens_hsa034601.19138935
58Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.18122291
59Viral myocarditis_Homo sapiens_hsa054161.15769337
60AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11214504
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.10780810
62Chemokine signaling pathway_Homo sapiens_hsa040621.08824644
63Leukocyte transendothelial migration_Homo sapiens_hsa046701.05916559
64Carbon metabolism_Homo sapiens_hsa012001.05684272
652-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.95779989
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94797406
67Acute myeloid leukemia_Homo sapiens_hsa052210.93879238
68Autoimmune thyroid disease_Homo sapiens_hsa053200.91294312
69Amoebiasis_Homo sapiens_hsa051460.87488397
70Non-small cell lung cancer_Homo sapiens_hsa052230.87265363
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.86856959
72Chronic myeloid leukemia_Homo sapiens_hsa052200.80927214
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79399375
74RNA transport_Homo sapiens_hsa030130.79009873
75Small cell lung cancer_Homo sapiens_hsa052220.78469069
76Epstein-Barr virus infection_Homo sapiens_hsa051690.76856897
77Viral carcinogenesis_Homo sapiens_hsa052030.76855514
78Caffeine metabolism_Homo sapiens_hsa002320.76653164
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76062076
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73722784
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.72997119
82Proteasome_Homo sapiens_hsa030500.72595204
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72535116
84Sphingolipid metabolism_Homo sapiens_hsa006000.71327025
85Pancreatic cancer_Homo sapiens_hsa052120.70935388
86Arginine biosynthesis_Homo sapiens_hsa002200.69668504
87Prolactin signaling pathway_Homo sapiens_hsa049170.69411740
88Spliceosome_Homo sapiens_hsa030400.68672718
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.65277991
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.62157821
91Purine metabolism_Homo sapiens_hsa002300.61752755
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61383665
93T cell receptor signaling pathway_Homo sapiens_hsa046600.60264112
94p53 signaling pathway_Homo sapiens_hsa041150.59087991
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58378402
96Neurotrophin signaling pathway_Homo sapiens_hsa047220.57351711
97One carbon pool by folate_Homo sapiens_hsa006700.56482326
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56320272
99HIF-1 signaling pathway_Homo sapiens_hsa040660.55528528
100Vibrio cholerae infection_Homo sapiens_hsa051100.54786246
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54519930
102Platelet activation_Homo sapiens_hsa046110.54175789
103Drug metabolism - other enzymes_Homo sapiens_hsa009830.53542174
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.53263668
105HTLV-I infection_Homo sapiens_hsa051660.52835812
106Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52625249
107Sulfur metabolism_Homo sapiens_hsa009200.50717987
108DNA replication_Homo sapiens_hsa030300.49556883
109Proteoglycans in cancer_Homo sapiens_hsa052050.48404112
110Prion diseases_Homo sapiens_hsa050200.47943463
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.42811576
112Folate biosynthesis_Homo sapiens_hsa007900.42336332
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41929939
114Renin-angiotensin system_Homo sapiens_hsa046140.40691299
115ABC transporters_Homo sapiens_hsa020100.40254622
116Insulin resistance_Homo sapiens_hsa049310.39982241
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.38248947
118Notch signaling pathway_Homo sapiens_hsa043300.38238655
119Galactose metabolism_Homo sapiens_hsa000520.38209046
120Ovarian steroidogenesis_Homo sapiens_hsa049130.38190553
121Glutathione metabolism_Homo sapiens_hsa004800.35623863
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35162244
123Focal adhesion_Homo sapiens_hsa045100.33515839
124mTOR signaling pathway_Homo sapiens_hsa041500.33510012
125VEGF signaling pathway_Homo sapiens_hsa043700.32643002
126Protein export_Homo sapiens_hsa030600.30998448
127N-Glycan biosynthesis_Homo sapiens_hsa005100.30564977
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.29270952
129Base excision repair_Homo sapiens_hsa034100.28520067
130Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27255492
131Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26938437
132MicroRNAs in cancer_Homo sapiens_hsa052060.26865326
133Pentose phosphate pathway_Homo sapiens_hsa000300.26407051
134Regulation of actin cytoskeleton_Homo sapiens_hsa048100.25323428
135Complement and coagulation cascades_Homo sapiens_hsa046100.24726401
136Endocytosis_Homo sapiens_hsa041440.24435212
137SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23489579
138Bladder cancer_Homo sapiens_hsa052190.22599084
139Adherens junction_Homo sapiens_hsa045200.21553474

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