TNFAIP8L3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of synapse maturation (GO:0090129)5.94610625
2vocalization behavior (GO:0071625)5.93330749
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.94012920
4behavioral response to nicotine (GO:0035095)4.73506028
5synaptic vesicle exocytosis (GO:0016079)4.69319167
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.52984998
7regulation of synapse maturation (GO:0090128)4.51316464
8neuron cell-cell adhesion (GO:0007158)4.44698777
9ionotropic glutamate receptor signaling pathway (GO:0035235)4.39165412
10protein localization to synapse (GO:0035418)4.37380698
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.29782071
12startle response (GO:0001964)4.12455477
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.05934235
14neuronal action potential propagation (GO:0019227)4.01154698
15regulation of glutamate receptor signaling pathway (GO:1900449)3.96569901
16gamma-aminobutyric acid transport (GO:0015812)3.90469324
17negative regulation of telomere maintenance (GO:0032205)3.88705013
18platelet dense granule organization (GO:0060155)3.82054894
19negative regulation of synaptic transmission, GABAergic (GO:0032229)3.81012073
20neurotransmitter secretion (GO:0007269)3.80314537
21glutamate receptor signaling pathway (GO:0007215)3.78358572
22indolalkylamine metabolic process (GO:0006586)3.77189706
23locomotory exploration behavior (GO:0035641)3.68462160
24response to pheromone (GO:0019236)3.66901492
25regulation of long-term neuronal synaptic plasticity (GO:0048169)3.64969827
26glutamate secretion (GO:0014047)3.58081573
27epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.57248615
28serotonin metabolic process (GO:0042428)3.53313691
29detection of calcium ion (GO:0005513)3.50251465
30negative regulation of mast cell activation (GO:0033004)3.48871344
31primary amino compound metabolic process (GO:1901160)3.47689154
32exploration behavior (GO:0035640)3.46669314
33detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.40897987
34neurotransmitter-gated ion channel clustering (GO:0072578)3.40189189
35response to histamine (GO:0034776)3.39094333
36regulation of excitatory postsynaptic membrane potential (GO:0060079)3.38796440
37glycerophospholipid catabolic process (GO:0046475)3.38256456
38regulation of neuronal synaptic plasticity (GO:0048168)3.37182554
39positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.36828039
40layer formation in cerebral cortex (GO:0021819)3.35509662
41protein polyglutamylation (GO:0018095)3.34720383
42piRNA metabolic process (GO:0034587)3.34248554
43L-fucose metabolic process (GO:0042354)3.33744161
44L-fucose catabolic process (GO:0042355)3.33744161
45fucose catabolic process (GO:0019317)3.33744161
46indole-containing compound catabolic process (GO:0042436)3.31430651
47indolalkylamine catabolic process (GO:0046218)3.31430651
48tryptophan catabolic process (GO:0006569)3.31430651
49lymphangiogenesis (GO:0001946)3.29721463
50long-term memory (GO:0007616)3.29517300
51regulation of synaptic vesicle exocytosis (GO:2000300)3.28823163
52kynurenine metabolic process (GO:0070189)3.27674016
53positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.26188624
54gamma-aminobutyric acid signaling pathway (GO:0007214)3.24923161
55negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.22843171
56succinate metabolic process (GO:0006105)3.22053467
57indole-containing compound metabolic process (GO:0042430)3.18504986
58cellular ketone body metabolic process (GO:0046950)3.18232992
59positive regulation of membrane potential (GO:0045838)3.16095608
60regulation of glucokinase activity (GO:0033131)3.16014699
61regulation of hexokinase activity (GO:1903299)3.16014699
62positive regulation of vesicle fusion (GO:0031340)3.15801620
63DNA deamination (GO:0045006)3.15519274
64synaptic vesicle maturation (GO:0016188)3.14990854
65pyrimidine nucleobase catabolic process (GO:0006208)3.13772436
66regulation of postsynaptic membrane potential (GO:0060078)3.13397382
67presynaptic membrane organization (GO:0097090)3.12506443
68epithelial cilium movement (GO:0003351)3.12201986
69regulation of cilium movement (GO:0003352)3.07600404
70regulation of synaptic transmission, glutamatergic (GO:0051966)3.06694255
71regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.05322525
72axoneme assembly (GO:0035082)3.03527869
73long-term synaptic potentiation (GO:0060291)3.02009100
74maternal behavior (GO:0042711)3.01865591
75synaptic transmission, glutamatergic (GO:0035249)3.01280894
76neuron recognition (GO:0008038)3.00744626
77kidney morphogenesis (GO:0060993)2.99166575
78ATP hydrolysis coupled proton transport (GO:0015991)2.98174348
79energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.98174348
80neuron-neuron synaptic transmission (GO:0007270)2.97374822
81detection of light stimulus involved in visual perception (GO:0050908)2.96386742
82detection of light stimulus involved in sensory perception (GO:0050962)2.96386742
83retinal cone cell development (GO:0046549)2.96234045
84regulation of synaptic plasticity (GO:0048167)2.95001873
85dendritic spine morphogenesis (GO:0060997)2.93611181
86regulation of synaptic vesicle transport (GO:1902803)2.93065294
87substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.92626166
88substrate-independent telencephalic tangential migration (GO:0021826)2.92626166
89phagosome maturation (GO:0090382)2.92617722
90neurotransmitter transport (GO:0006836)2.92293651
91ketone body metabolic process (GO:1902224)2.92039386
92protein localization to cilium (GO:0061512)2.92001887
93axon ensheathment in central nervous system (GO:0032291)2.91769897
94central nervous system myelination (GO:0022010)2.91769897
95proline transport (GO:0015824)2.82683995
96cilium morphogenesis (GO:0060271)2.80613248
97negative regulation of amino acid transport (GO:0051956)2.79473527
98blood vessel maturation (GO:0001955)2.77526445
99water-soluble vitamin biosynthetic process (GO:0042364)2.76635980
100innervation (GO:0060384)2.75250036
101regulation of microtubule-based movement (GO:0060632)2.74894725
102nucleobase catabolic process (GO:0046113)2.73132613
103regulation of neurotransmitter uptake (GO:0051580)2.73047605
104synapse assembly (GO:0007416)2.72491198
105positive regulation of synapse assembly (GO:0051965)2.70926728
106synapsis (GO:0007129)2.70857670
107regulation of inositol phosphate biosynthetic process (GO:0010919)2.70470545
108regulation of telomere maintenance (GO:0032204)2.70295481
109G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.70104506
110hydrogen peroxide biosynthetic process (GO:0050665)2.69896223
111tryptophan metabolic process (GO:0006568)2.69552313
112behavioral response to ethanol (GO:0048149)2.67960723
113mating behavior (GO:0007617)2.66424050
114regulation of glutamate secretion (GO:0014048)2.66360125
115protein complex biogenesis (GO:0070271)2.66245859
116regulation of neurotransmitter levels (GO:0001505)2.64896282
117transferrin transport (GO:0033572)2.64858694
118negative regulation of amine transport (GO:0051953)2.64858042
119regulation of vesicle fusion (GO:0031338)2.64810324
120neuronal action potential (GO:0019228)2.64487437
121cerebellar granule cell differentiation (GO:0021707)2.64004004
122multi-organism reproductive behavior (GO:0044705)2.62051828
123cAMP catabolic process (GO:0006198)2.61285351
124DNA methylation involved in gamete generation (GO:0043046)2.61199956
125positive regulation of action potential (GO:0045760)2.60201559
126learning (GO:0007612)2.59145119
127parturition (GO:0007567)2.56577904
128behavioral response to cocaine (GO:0048148)2.56470848
129parental behavior (GO:0060746)2.56323173
130cilium movement (GO:0003341)2.54725948
131axonal fasciculation (GO:0007413)2.54362637
132intraspecies interaction between organisms (GO:0051703)2.54186606
133social behavior (GO:0035176)2.54186606
134postsynaptic membrane organization (GO:0001941)2.54058574
135inner ear receptor stereocilium organization (GO:0060122)2.53709074
136regulation of dendritic spine morphogenesis (GO:0061001)2.53382701
137multicellular organismal reproductive behavior (GO:0033057)2.53085887
138male meiosis I (GO:0007141)2.52133638
139G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.51813113
140behavioral fear response (GO:0001662)2.51582502
141behavioral defense response (GO:0002209)2.51582502
142dopamine transport (GO:0015872)2.51353031
143alanine transport (GO:0032328)2.51297303
144membrane depolarization (GO:0051899)2.48811625
145reproductive behavior (GO:0019098)2.48679251
146nonmotile primary cilium assembly (GO:0035058)2.46975054
147ferric iron transport (GO:0015682)2.46920495
148trivalent inorganic cation transport (GO:0072512)2.46920495
149photoreceptor cell maintenance (GO:0045494)2.46710989
150regulation of synaptic transmission, GABAergic (GO:0032228)2.46498056
151reflex (GO:0060004)2.46032156
152negative regulation of cytosolic calcium ion concentration (GO:0051481)2.45646536
153regulation of fever generation (GO:0031620)2.45582505
154positive regulation of dendritic spine morphogenesis (GO:0061003)2.45203491
155cilium organization (GO:0044782)2.45078232
156regulation of amino acid transport (GO:0051955)2.44707404
157phosphatidylinositol acyl-chain remodeling (GO:0036149)2.44597146
158mitochondrial respiratory chain complex I assembly (GO:0032981)2.44544855
159NADH dehydrogenase complex assembly (GO:0010257)2.44544855
160mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.44544855
161neurotransmitter metabolic process (GO:0042133)2.44343548
162positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.42642020
163positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.42541256
164cellular response to ATP (GO:0071318)2.42149186
165regulation of feeding behavior (GO:0060259)2.41959714
166suckling behavior (GO:0001967)2.41947991
167auditory receptor cell stereocilium organization (GO:0060088)2.41806592
168positive regulation of synaptic transmission (GO:0050806)2.40706508
169positive regulation of heat generation (GO:0031652)2.40376139
170organic cation transport (GO:0015695)2.40239630
171photoreceptor cell development (GO:0042461)2.40106131
172cyclic nucleotide catabolic process (GO:0009214)2.39863489
173regulation of action potential (GO:0098900)2.39479573
174transmission of nerve impulse (GO:0019226)2.39315922
175regulation of penile erection (GO:0060405)2.38859596
176mitochondrial respiratory chain complex assembly (GO:0033108)2.38854687
177positive regulation of muscle hypertrophy (GO:0014742)2.38785097
178positive regulation of cardiac muscle hypertrophy (GO:0010613)2.38785097
179cornea development in camera-type eye (GO:0061303)2.38782911
180response to cocaine (GO:0042220)2.38572827
181presynaptic membrane assembly (GO:0097105)2.38564280
182respiratory chain complex IV assembly (GO:0008535)2.36506799
183phosphatidylserine acyl-chain remodeling (GO:0036150)2.35647276
184cilium assembly (GO:0042384)2.35514373
185preassembly of GPI anchor in ER membrane (GO:0016254)2.33690767
186synaptic transmission, cholinergic (GO:0007271)2.33675013
187adaptation of signaling pathway (GO:0023058)2.33049147
188positive regulation of fatty acid transport (GO:2000193)2.32988901
189protein K11-linked deubiquitination (GO:0035871)2.32199064
190phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.31763180
191detection of mechanical stimulus involved in sensory perception (GO:0050974)2.30140667
192negative regulation of transcription regulatory region DNA binding (GO:2000678)2.30117239
193phasic smooth muscle contraction (GO:0014821)2.29005425
194regulation of dopamine secretion (GO:0014059)2.28918297

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.11164973
2GBX2_23144817_ChIP-Seq_PC3_Human3.46335040
3* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.94942104
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.89175758
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.82858666
6* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.70649782
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44297378
8SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42427266
9* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.27628091
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.25094272
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.25094272
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.24157649
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.15826674
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.12279676
15IKZF1_21737484_ChIP-ChIP_HCT116_Human2.07904528
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.06921854
17TAF15_26573619_Chip-Seq_HEK293_Human2.03654395
18FLI1_27457419_Chip-Seq_LIVER_Mouse2.02152038
19AR_21572438_ChIP-Seq_LNCaP_Human1.99452114
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96617385
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.93017296
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92325859
23CDX2_19796622_ChIP-Seq_MESCs_Mouse1.91037850
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.86188103
25* REST_21632747_ChIP-Seq_MESCs_Mouse1.83701853
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.81688212
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80844610
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.76799119
29P300_19829295_ChIP-Seq_ESCs_Human1.76710671
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.71759169
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.70498966
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.69071900
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68652632
34SMAD_19615063_ChIP-ChIP_OVARY_Human1.64348957
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.63530793
36EWS_26573619_Chip-Seq_HEK293_Human1.61759925
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60942847
38TP53_18474530_ChIP-ChIP_U2OS_Human1.54699137
39DROSHA_22980978_ChIP-Seq_HELA_Human1.53622969
40OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53058552
41IGF1R_20145208_ChIP-Seq_DFB_Human1.52406344
42CBP_20019798_ChIP-Seq_JUKART_Human1.51826939
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51826939
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.51298991
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.50795082
46POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49460901
47* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49218203
48MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.48179536
49NR3C1_23031785_ChIP-Seq_PC12_Mouse1.47421358
50REST_18959480_ChIP-ChIP_MESCs_Mouse1.45719310
51NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.45105063
52TP53_22573176_ChIP-Seq_HFKS_Human1.40265740
53PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39463543
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39127360
55HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.38768943
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38494586
57AR_25329375_ChIP-Seq_VCAP_Human1.38392276
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.36818866
59TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36651735
60RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36274516
61SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36243362
62CBX2_27304074_Chip-Seq_ESCs_Mouse1.34356111
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33613603
64RARB_27405468_Chip-Seq_BRAIN_Mouse1.33496260
65AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32834303
66FUS_26573619_Chip-Seq_HEK293_Human1.31776377
67RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31580597
68SOX2_19829295_ChIP-Seq_ESCs_Human1.31454422
69NANOG_19829295_ChIP-Seq_ESCs_Human1.31454422
70BCAT_22108803_ChIP-Seq_LS180_Human1.29816732
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29262818
72NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.27661982
73NRF2_20460467_ChIP-Seq_MEFs_Mouse1.27661982
74Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26554366
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25447231
76TRIM28_21343339_ChIP-Seq_HEK293_Human1.24444838
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22845902
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.21076233
79* SOX2_21211035_ChIP-Seq_LN229_Gbm1.19903739
80BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.19818403
81BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.19484959
82FOXA1_25329375_ChIP-Seq_VCAP_Human1.19364934
83FOXA1_27270436_Chip-Seq_PROSTATE_Human1.19364934
84GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19076331
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18677695
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18677695
87SMAD4_21741376_ChIP-Seq_EPCs_Human1.17280644
88GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.16869657
89NCOR_22424771_ChIP-Seq_293T_Human1.16810629
90EZH2_27294783_Chip-Seq_NPCs_Mouse1.16651026
91IRF1_19129219_ChIP-ChIP_H3396_Human1.16570698
92FOXA1_21572438_ChIP-Seq_LNCaP_Human1.15910986
93CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.14812815
94NFE2_27457419_Chip-Seq_LIVER_Mouse1.14745072
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13703862
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13196350
97* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.11720533
98BP1_19119308_ChIP-ChIP_Hs578T_Human1.11675627
99VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.11600654
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11558520
101GATA3_21878914_ChIP-Seq_MCF-7_Human1.11071644
102AHR_22903824_ChIP-Seq_MCF-7_Human1.10556024
103EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10102224
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09482429
105VDR_22108803_ChIP-Seq_LS180_Human1.08216352
106PRDM14_20953172_ChIP-Seq_ESCs_Human1.07549421
107EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06875052
108JUN_21703547_ChIP-Seq_K562_Human1.05559213
109IRF8_21731497_ChIP-ChIP_J774_Mouse1.05200383
110ER_23166858_ChIP-Seq_MCF-7_Human1.04906913
111FLI1_21867929_ChIP-Seq_TH2_Mouse1.04489610
112ARNT_22903824_ChIP-Seq_MCF-7_Human1.03626590
113ERG_21242973_ChIP-ChIP_JURKAT_Human1.02546935
114STAT3_23295773_ChIP-Seq_U87_Human1.02414826
115NANOG_18555785_Chip-Seq_ESCs_Mouse1.01412081
116AUTS2_25519132_ChIP-Seq_293T-REX_Human1.01306707
117ETV2_25802403_ChIP-Seq_MESCs_Mouse1.00659540
118CJUN_26792858_Chip-Seq_BT549_Human1.00366750
119TP53_16413492_ChIP-PET_HCT116_Human0.99976740
120CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.99957861
121CDX2_22108803_ChIP-Seq_LS180_Human0.99925761
122CRX_20693478_ChIP-Seq_RETINA_Mouse0.99482092
123FOXH1_21741376_ChIP-Seq_EPCs_Human0.99370308
124RING1B_27294783_Chip-Seq_ESCs_Mouse0.99080091
125RUNX2_22187159_ChIP-Seq_PCA_Human0.98949152
126AR_20517297_ChIP-Seq_VCAP_Human0.98416239
127TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98276271
128YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98268090
129NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97698244
130RNF2_27304074_Chip-Seq_NSC_Mouse0.95567708
131KDM2B_26808549_Chip-Seq_REH_Human0.94745489
132RXR_22108803_ChIP-Seq_LS180_Human0.93232371
133ZNF274_21170338_ChIP-Seq_K562_Hela0.92922065
134* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92743352
135* AR_19668381_ChIP-Seq_PC3_Human0.92530565
136* TCF4_23295773_ChIP-Seq_U87_Human0.89582358
137TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.85899721
138TCF4_22108803_ChIP-Seq_LS180_Human0.85541444
139RBPJ_22232070_ChIP-Seq_NCS_Mouse0.84836890
140P53_22387025_ChIP-Seq_ESCs_Mouse0.84713003
141WT1_25993318_ChIP-Seq_PODOCYTE_Human0.84572290

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.71479800
2MP0002822_catalepsy4.00749447
3MP0003635_abnormal_synaptic_transmissio3.80023937
4MP0003880_abnormal_central_pattern3.55892203
5MP0008877_abnormal_DNA_methylation3.54280712
6MP0009745_abnormal_behavioral_response3.32853113
7MP0001501_abnormal_sleep_pattern3.31644705
8MP0002064_seizures3.26827522
9MP0009046_muscle_twitch3.22562771
10MP0002063_abnormal_learning/memory/cond3.12374318
11MP0003787_abnormal_imprinting2.81942684
12MP0004270_analgesia2.81603535
13MP0002735_abnormal_chemical_nociception2.78153968
14MP0002572_abnormal_emotion/affect_behav2.72573059
15MP0003195_calcinosis2.60071192
16MP0002102_abnormal_ear_morphology2.55269265
17MP0003329_amyloid_beta_deposits2.44181021
18MP0005551_abnormal_eye_electrophysiolog2.41951263
19MP0010386_abnormal_urinary_bladder2.29854755
20MP0003646_muscle_fatigue2.22361495
21MP0005167_abnormal_blood-brain_barrier2.20501569
22MP0000604_amyloidosis2.17723011
23MP0002272_abnormal_nervous_system2.10729077
24MP0004133_heterotaxia2.07996371
25MP0010234_abnormal_vibrissa_follicle1.95441064
26MP0008004_abnormal_stomach_pH1.91942550
27MP0004043_abnormal_pH_regulation1.88212974
28MP0001968_abnormal_touch/_nociception1.86035155
29MP0002734_abnormal_mechanical_nocicepti1.83842056
30MP0009780_abnormal_chondrocyte_physiolo1.81563694
31MP0002837_dystrophic_cardiac_calcinosis1.78615506
32MP0001440_abnormal_grooming_behavior1.77300672
33MP0008875_abnormal_xenobiotic_pharmacok1.76798986
34MP0003011_delayed_dark_adaptation1.76645453
35MP0001486_abnormal_startle_reflex1.74947476
36MP0002653_abnormal_ependyma_morphology1.70975733
37MP0005253_abnormal_eye_physiology1.62318287
38MP0002184_abnormal_innervation1.62186236
39MP0002733_abnormal_thermal_nociception1.61010220
40MP0001986_abnormal_taste_sensitivity1.60325398
41MP0002067_abnormal_sensory_capabilities1.58413044
42MP0006054_spinal_hemorrhage1.55346178
43MP0000427_abnormal_hair_cycle1.53690661
44MP0005646_abnormal_pituitary_gland1.51796087
45MP0006082_CNS_inflammation1.51704074
46MP0006072_abnormal_retinal_apoptosis1.50830595
47MP0002557_abnormal_social/conspecific_i1.50693235
48MP0004858_abnormal_nervous_system1.50050856
49MP0001970_abnormal_pain_threshold1.49315309
50MP0004885_abnormal_endolymph1.45308197
51MP0004742_abnormal_vestibular_system1.44283665
52MP0003690_abnormal_glial_cell1.43379416
53MP0002148_abnormal_hypersensitivity_rea1.39974220
54MP0008569_lethality_at_weaning1.39920107
55MP0006292_abnormal_olfactory_placode1.37483305
56MP0010368_abnormal_lymphatic_system1.37481433
57MP0008872_abnormal_physiological_respon1.36751676
58MP0002909_abnormal_adrenal_gland1.35916530
59MP0003879_abnormal_hair_cell1.30680903
60MP0004510_myositis1.29841109
61MP0003303_peritoneal_inflammation1.28690263
62MP0002254_reproductive_system_inflammat1.28394455
63MP0004811_abnormal_neuron_physiology1.27351702
64MP0000647_abnormal_sebaceous_gland1.25352806
65MP0002090_abnormal_vision1.22637691
66MP0002138_abnormal_hepatobiliary_system1.22201376
67MP0005084_abnormal_gallbladder_morpholo1.21043215
68MP0004924_abnormal_behavior1.20836116
69MP0005386_behavior/neurological_phenoty1.20836116
70MP0003075_altered_response_to1.18890769
71MP0001502_abnormal_circadian_rhythm1.18831336
72MP0004215_abnormal_myocardial_fiber1.17563152
73MP0000778_abnormal_nervous_system1.17046940
74MP0004145_abnormal_muscle_electrophysio1.16278652
75MP0001984_abnormal_olfaction1.15720597
76MP0002638_abnormal_pupillary_reflex1.15333860
77MP0005389_reproductive_system_phenotype1.14693051
78MP0002736_abnormal_nociception_after1.10597647
79MP0005195_abnormal_posterior_eye1.09307502
80MP0003283_abnormal_digestive_organ1.08426762
81MP0003436_decreased_susceptibility_to1.07780430
82MP0002066_abnormal_motor_capabilities/c1.06934729
83MP0002277_abnormal_respiratory_mucosa1.06186672
84MP0003633_abnormal_nervous_system1.05564801
85MP0000230_abnormal_systemic_arterial1.05481300
86MP0005423_abnormal_somatic_nervous1.04645231
87MP0008995_early_reproductive_senescence1.04337854
88MP0000569_abnormal_digit_pigmentation1.03301189
89MP0002160_abnormal_reproductive_system1.03056448
90MP0008874_decreased_physiological_sensi1.01105235
91MP0003122_maternal_imprinting0.99095230
92MP0004085_abnormal_heartbeat0.98902981
93MP0005367_renal/urinary_system_phenotyp0.97638053
94MP0000516_abnormal_urinary_system0.97638053
95MP0000013_abnormal_adipose_tissue0.97553830
96MP0003631_nervous_system_phenotype0.97309955
97MP0002752_abnormal_somatic_nervous0.97121011
98MP0008775_abnormal_heart_ventricle0.96370383
99MP0005595_abnormal_vascular_smooth0.96117411
100MP0005171_absent_coat_pigmentation0.96079345
101MP0001879_abnormal_lymphatic_vessel0.95377823
102MP0003121_genomic_imprinting0.95311371
103MP0000631_abnormal_neuroendocrine_gland0.95046563
104MP0001188_hyperpigmentation0.94277117
105MP0000026_abnormal_inner_ear0.94085930
106MP0002229_neurodegeneration0.93351123
107MP0003172_abnormal_lysosome_physiology0.92965161
108MP0005187_abnormal_penis_morphology0.92649865
109MP0009785_altered_susceptibility_to0.92133405
110MP0000049_abnormal_middle_ear0.91189906
111MP0001177_atelectasis0.90666330
112MP0005410_abnormal_fertilization0.90412578
113MP0001881_abnormal_mammary_gland0.89412238
114MP0005164_abnormal_response_to0.88237242
115MP0002882_abnormal_neuron_morphology0.88123793
116MP0003950_abnormal_plasma_membrane0.87439631
117MP0006276_abnormal_autonomic_nervous0.87082494
118MP0001963_abnormal_hearing_physiology0.86775364
119MP0010678_abnormal_skin_adnexa0.86501816
120MP0005535_abnormal_body_temperature0.86477921
121MP0004142_abnormal_muscle_tone0.85937862
122MP0003724_increased_susceptibility_to0.85259211
123MP0005257_abnormal_intraocular_pressure0.85211802
124MP0001324_abnormal_eye_pigmentation0.84591805
125MP0001485_abnormal_pinna_reflex0.82133038
126MP0001529_abnormal_vocalization0.82070540
127MP0001664_abnormal_digestion0.81710958
128MP0002876_abnormal_thyroid_physiology0.81516592
129MP0001919_abnormal_reproductive_system0.81283512
130MP0003632_abnormal_nervous_system0.80667421
131MP0000955_abnormal_spinal_cord0.79205391
132MP0005166_decreased_susceptibility_to0.78331301
133MP0005000_abnormal_immune_tolerance0.78302810
134MP0002938_white_spotting0.78229981
135MP0000372_irregular_coat_pigmentation0.77186763
136MP0002419_abnormal_innate_immunity0.76432399
137MP0005379_endocrine/exocrine_gland_phen0.74949503
138MP0002163_abnormal_gland_morphology0.74152837
139MP0001905_abnormal_dopamine_level0.74012620
140MP0002928_abnormal_bile_duct0.72687990
141MP0002693_abnormal_pancreas_physiology0.71719442
142MP0005645_abnormal_hypothalamus_physiol0.71523913
143MP0001835_abnormal_antigen_presentation0.70911446
144MP0002234_abnormal_pharynx_morphology0.69973498
145MP0003119_abnormal_digestive_system0.69965943
146MP0000538_abnormal_urinary_bladder0.69558123
147MP0009384_cardiac_valve_regurgitation0.67910148
148MP0005310_abnormal_salivary_gland0.67529249
149MP0004130_abnormal_muscle_cell0.66766130
150MP0002069_abnormal_eating/drinking_beha0.66632908
151MP0005671_abnormal_response_to0.66481966
152MP0000383_abnormal_hair_follicle0.66429407
153MP0004883_abnormal_blood_vessel0.63212202
154MP0002332_abnormal_exercise_endurance0.63171100
155MP0004484_altered_response_of0.62757785
156MP0003634_abnormal_glial_cell0.62137736
157MP0000920_abnormal_myelination0.61561095

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.43618970
2Focal seizures (HP:0007359)5.28141041
3Hyperventilation (HP:0002883)5.26694390
4Absence seizures (HP:0002121)4.97359679
5Atonic seizures (HP:0010819)4.95772367
6Dialeptic seizures (HP:0011146)4.74615176
7Febrile seizures (HP:0002373)4.71495017
8Visual hallucinations (HP:0002367)4.61469031
9Pancreatic cysts (HP:0001737)4.49132679
10Epileptic encephalopathy (HP:0200134)4.46245201
11Pancreatic fibrosis (HP:0100732)4.13270872
12Molar tooth sign on MRI (HP:0002419)4.13103548
13Abnormality of midbrain morphology (HP:0002418)4.13103548
14Generalized tonic-clonic seizures (HP:0002069)4.02847160
15Progressive inability to walk (HP:0002505)3.93432533
16Congenital stationary night blindness (HP:0007642)3.91384274
17Type II lissencephaly (HP:0007260)3.91315755
18True hermaphroditism (HP:0010459)3.89749693
19Progressive cerebellar ataxia (HP:0002073)3.89417257
20Myokymia (HP:0002411)3.87307488
21Cerebral inclusion bodies (HP:0100314)3.71680599
22Nephronophthisis (HP:0000090)3.69361593
23Neurofibrillary tangles (HP:0002185)3.64716801
24Medial flaring of the eyebrow (HP:0010747)3.27372254
25Dynein arm defect of respiratory motile cilia (HP:0012255)3.22609010
26Absent/shortened dynein arms (HP:0200106)3.22609010
27Abnormality of the renal cortex (HP:0011035)3.17516432
28Abnormality of the renal medulla (HP:0100957)3.09562767
29Recurrent bacterial skin infections (HP:0005406)3.09252760
30Chronic hepatic failure (HP:0100626)3.06890194
31Amblyopia (HP:0000646)3.00162645
32Increased IgM level (HP:0003496)2.93756398
33Abnormality of alanine metabolism (HP:0010916)2.90301982
34Hyperalaninemia (HP:0003348)2.90301982
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.90301982
36Abnormality of binocular vision (HP:0011514)2.88048907
37Diplopia (HP:0000651)2.88048907
38Recurrent gram-negative bacterial infections (HP:0005420)2.87187859
39Keratoconus (HP:0000563)2.84290047
40Increased corneal curvature (HP:0100692)2.84290047
41Absent speech (HP:0001344)2.79079417
42Gait imbalance (HP:0002141)2.78184204
43Eczematoid dermatitis (HP:0000976)2.75435545
44Action tremor (HP:0002345)2.75345116
45Impaired social interactions (HP:0000735)2.73663066
46Abnormal social behavior (HP:0012433)2.73663066
47Recurrent abscess formation (HP:0002722)2.72946578
48Cystic liver disease (HP:0006706)2.72871337
49Renal cortical cysts (HP:0000803)2.67217838
50Abolished electroretinogram (ERG) (HP:0000550)2.66293022
51Thickened helices (HP:0000391)2.64233061
52Supranuclear gaze palsy (HP:0000605)2.59126968
53Attenuation of retinal blood vessels (HP:0007843)2.59083230
54Lissencephaly (HP:0001339)2.58727427
55Truncal ataxia (HP:0002078)2.56203511
56Tubular atrophy (HP:0000092)2.55977191
57Thick nail (HP:0001805)2.55658337
58Congenital primary aphakia (HP:0007707)2.54088436
59Abnormal respiratory motile cilium morphology (HP:0005938)2.54042535
60Abnormal respiratory epithelium morphology (HP:0012253)2.54042535
61Abnormal rod and cone electroretinograms (HP:0008323)2.53112064
62Abnormality of macrophages (HP:0004311)2.50596237
63Papilledema (HP:0001085)2.47095837
64Gaze-evoked nystagmus (HP:0000640)2.46600692
65Aplasia/Hypoplasia of the tongue (HP:0010295)2.46246833
66Broad-based gait (HP:0002136)2.46131208
67Fair hair (HP:0002286)2.45973614
68Nephrogenic diabetes insipidus (HP:0009806)2.45964654
69Anxiety (HP:0000739)2.45652514
70Polydipsia (HP:0001959)2.45605289
71Abnormal drinking behavior (HP:0030082)2.45605289
72Hemiparesis (HP:0001269)2.45023469
73Epileptiform EEG discharges (HP:0011182)2.42726857
74Mediastinal lymphadenopathy (HP:0100721)2.42482372
75Excessive salivation (HP:0003781)2.41724191
76Drooling (HP:0002307)2.41724191
77Stomatitis (HP:0010280)2.40759369
78Cerebellar dysplasia (HP:0007033)2.40012868
79Methylmalonic acidemia (HP:0002912)2.39440304
80Inability to walk (HP:0002540)2.38406319
81Generalized myoclonic seizures (HP:0002123)2.38234390
82Poor eye contact (HP:0000817)2.37981944
83Decreased circulating renin level (HP:0003351)2.34179483
84Pendular nystagmus (HP:0012043)2.31388099
85Limb dystonia (HP:0002451)2.31356389
86Clumsiness (HP:0002312)2.30402435
87Blue irides (HP:0000635)2.29866805
88Protruding tongue (HP:0010808)2.27860435
89Congenital hepatic fibrosis (HP:0002612)2.27515289
90Severe muscular hypotonia (HP:0006829)2.27113652
91Aplasia/Hypoplasia of the tibia (HP:0005772)2.27048988
92Large for gestational age (HP:0001520)2.26944100
93Cerebral hemorrhage (HP:0001342)2.26587590
94Retinal atrophy (HP:0001105)2.25733142
95Pachygyria (HP:0001302)2.25691307
96Occipital encephalocele (HP:0002085)2.25159035
97Increased cerebral lipofuscin (HP:0011813)2.24304767
98Sclerocornea (HP:0000647)2.23934182
99Increased neuronal autofluorescent lipopigment (HP:0002074)2.23737389
100Generalized hypopigmentation of hair (HP:0011358)2.23471041
101Inappropriate behavior (HP:0000719)2.23183829
102Mutism (HP:0002300)2.22191683
103Abnormal ciliary motility (HP:0012262)2.19951344
104Intestinal atresia (HP:0011100)2.18670452
105EEG with generalized epileptiform discharges (HP:0011198)2.17157038
106Decreased central vision (HP:0007663)2.17148000
107Congenital, generalized hypertrichosis (HP:0004540)2.16962670
108Retinal dysplasia (HP:0007973)2.16755367
109Anencephaly (HP:0002323)2.14633462
110Amyloidosis (HP:0011034)2.12450913
111Disproportionate short-trunk short stature (HP:0003521)2.11412408
112Absent rod-and cone-mediated responses on ERG (HP:0007688)2.10661590
113Depression (HP:0000716)2.09969228
114Psychosis (HP:0000709)2.08000940
115Male pseudohermaphroditism (HP:0000037)2.06588000
116Postural instability (HP:0002172)2.02107965
117Stomach cancer (HP:0012126)2.01789660
118Parakeratosis (HP:0001036)2.01096546
119Abnormality of salivation (HP:0100755)2.00927504
120Abnormality of the labia minora (HP:0012880)2.00503232
121Hematochezia (HP:0002573)2.00025377
122Bile duct proliferation (HP:0001408)1.99712864
123Abnormal biliary tract physiology (HP:0012439)1.99712864
124Hypsarrhythmia (HP:0002521)1.99562650
125Choroideremia (HP:0001139)1.99297781
126Bulbous nose (HP:0000414)1.98601450
127Genital tract atresia (HP:0001827)1.98114293
128Agitation (HP:0000713)1.97578176
129Mitochondrial inheritance (HP:0001427)1.96406958
130Stereotypic behavior (HP:0000733)1.95983849
131Dysmetria (HP:0001310)1.95727515
132Furrowed tongue (HP:0000221)1.95145758
133Methylmalonic aciduria (HP:0012120)1.94319745
134Dysdiadochokinesis (HP:0002075)1.94271365
135Widely spaced teeth (HP:0000687)1.91333222
136Spastic tetraparesis (HP:0001285)1.90309183
137Short tibia (HP:0005736)1.90072155
1383-Methylglutaconic aciduria (HP:0003535)1.89563533
139Anterior segment dysgenesis (HP:0007700)1.89488323
140Abnormality of macular pigmentation (HP:0008002)1.89217117
141Vaginal atresia (HP:0000148)1.88978694
142Hyperthyroidism (HP:0000836)1.88802211
143Abnormal eating behavior (HP:0100738)1.88554194
144Increased CSF lactate (HP:0002490)1.86982690
145Status epilepticus (HP:0002133)1.86446757
146Polyphagia (HP:0002591)1.84733935
147Hypoplasia of the fovea (HP:0007750)1.84363443
148Aplasia/Hypoplasia of the fovea (HP:0008060)1.84363443
149Acute encephalopathy (HP:0006846)1.83453235
150Exotropia (HP:0000577)1.81941442
151Prolonged QT interval (HP:0001657)1.77441246
152Spastic diplegia (HP:0001264)1.77178916
153Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77022425
154Polyuria (HP:0000103)1.77011286
155Dandy-Walker malformation (HP:0001305)1.76985067
156Gingivitis (HP:0000230)1.75799957
157Arterial tortuosity (HP:0005116)1.73445672
158Dementia (HP:0000726)1.69457810
159Palmoplantar hyperkeratosis (HP:0000972)1.67935539
160Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.67549091
161Hemiplegia (HP:0002301)1.67050836
162Plantar hyperkeratosis (HP:0007556)1.64870772
163Systemic lupus erythematosus (HP:0002725)1.63381732
164Vacuolated lymphocytes (HP:0001922)1.61861594
165Spontaneous abortion (HP:0005268)1.60642074
166X-linked dominant inheritance (HP:0001423)1.60389150
167Epidermoid cyst (HP:0200040)1.60110742
168Intellectual disability, progressive (HP:0006887)1.59404882
169Progressive visual loss (HP:0000529)1.56810816
170Heterochromia iridis (HP:0001100)1.52547698
171Recurrent skin infections (HP:0001581)1.50987817
172Autoimmune thrombocytopenia (HP:0001973)1.49857424
173Acute necrotizing encephalopathy (HP:0006965)1.49202463
174Apathy (HP:0000741)1.49025257
175Tented upper lip vermilion (HP:0010804)1.48877700
176Gait ataxia (HP:0002066)1.47776271
177Progressive macrocephaly (HP:0004481)1.46991689

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK45.27139100
2NTRK34.19289311
3TIE13.81644443
4ADRBK23.42138483
5PINK13.33990563
6MAP3K93.14442934
7ACVR1B3.02702859
8EPHA42.93178979
9MAP3K122.81718871
10MAP4K22.62139631
11MAP2K72.51707287
12GRK12.46977255
13MAP3K42.38527931
14ERBB42.16238653
15BMPR22.15012661
16MAP3K132.14395937
17BMPR1B2.08959036
18KSR12.01767065
19TLK12.01238656
20MAP2K42.00269443
21KSR21.97535146
22BCKDK1.95096721
23WNK41.93030571
24NTRK11.92794695
25MINK11.87402794
26ARAF1.86849606
27PBK1.82555775
28GRK51.81990573
29CASK1.78993152
30PLK21.74750401
31FGR1.59674967
32FRK1.58022107
33SIK31.51098587
34TGFBR11.46046453
35PTK2B1.44023748
36NUAK11.41318175
37MAP3K21.40194689
38DAPK11.36978554
39MAPKAPK31.36882121
40FES1.36416766
41SIK21.34446340
42MST41.34244191
43DAPK21.34146125
44PRKCE1.27915549
45ADRBK11.24848422
46PHKG21.23811774
47PHKG11.23811774
48NTRK21.21705966
49ZAK1.20834378
50TGFBR21.18914385
51MAP3K141.17832983
52DYRK21.15895202
53TXK1.14080077
54OXSR11.13661108
55MST1R1.13034141
56TNIK1.12760455
57PRKCG1.10865923
58AKT31.08113348
59CDK51.07580188
60CAMK2A1.06021357
61ERBB31.04006403
62EPHB21.03733900
63WNK31.03591143
64PAK60.98783740
65ABL20.97814024
66PNCK0.97013772
67STK390.93780112
68TEC0.93680201
69CSNK1G20.87637204
70STK38L0.87320590
71MAPKAPK50.86066525
72TRIM280.85754823
73CSNK1G10.83720113
74NME10.81983967
75MARK10.81831905
76BCR0.78249326
77RAF10.77999504
78SYK0.77104729
79TBK10.76033583
80CSNK1G30.75921509
81LIMK10.75317079
82PDK20.74959837
83PRKD30.73989096
84MAP3K10.73972030
85PAK30.72936957
86CAMK2B0.72341845
87CAMKK10.71667996
88MATK0.71343084
89FER0.69822301
90CSNK1A1L0.66283087
91MAP3K50.65602620
92PRKCZ0.65507992
93SGK10.64511954
94FYN0.63662356
95SCYL20.63628689
96PKN10.61006992
97MUSK0.60263321
98MAP2K10.60072114
99MAPK150.59654501
100FLT30.59610164
101PRKCQ0.59334052
102PRKCH0.59285413
103CDK140.59163114
104PRKCI0.58880974
105CAMK1D0.58236925
106GRK60.57148326
107DYRK1A0.57124098
108ITK0.56722087
109IRAK20.56676219
110MAP2K60.56660329
111RIPK10.54802426
112NEK60.54717067
113PDK10.53834821
114VRK10.53383314
115GRK70.52041809
116MAPK130.51799587
117PIK3CA0.49707563
118CAMK1G0.49531315
119BMX0.48688713
120BLK0.48211184
121MAP3K60.47463256
122CDK180.45677139
123SGK4940.45028135
124SGK2230.45028135
125PRKACA0.44267605
126MOS0.44135395
127EPHA30.43741059
128SGK20.43739530
129IRAK10.43565879
130YES10.42494499
131BRSK20.42233945
132TYRO30.41897482
133SRC0.41727097
134DDR20.41493911
135CAMK2D0.41448973
136STK380.40908042
137PRPF4B0.40318597
138TAOK30.40142485
139CSNK1A10.39925686
140PIM20.39847686
141BRAF0.39589076
142PRKCD0.38841494
143CDK150.38774822
144CAMK10.37322598
145PRKAA10.36316271
146CSNK1D0.35830757
147EIF2AK30.35640289
148IKBKB0.35425301
149STK110.35242673
150PRKCA0.34927014
151PDPK10.34748741
152UHMK10.34583806
153FGFR20.34387875
154RET0.34332074
155PRKAA20.34241866
156MKNK20.33997829
157PRKG10.33335617
158ABL10.33001910
159IGF1R0.32717297
160INSRR0.32586561
161CAMKK20.32549000
162PRKCB0.32099928

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.30168288
2Synaptic vesicle cycle_Homo sapiens_hsa047212.99369412
3Phototransduction_Homo sapiens_hsa047442.85607285
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.78416581
5GABAergic synapse_Homo sapiens_hsa047272.71162498
6Type I diabetes mellitus_Homo sapiens_hsa049402.66842972
7Collecting duct acid secretion_Homo sapiens_hsa049662.47859688
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.47266986
9Linoleic acid metabolism_Homo sapiens_hsa005912.42570808
10alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.36372027
11Long-term potentiation_Homo sapiens_hsa047202.31169049
12Morphine addiction_Homo sapiens_hsa050322.13997052
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13834326
14Circadian entrainment_Homo sapiens_hsa047132.08225806
15Glutamatergic synapse_Homo sapiens_hsa047242.05623230
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.99659483
17Protein export_Homo sapiens_hsa030601.99173742
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.94884783
19Ether lipid metabolism_Homo sapiens_hsa005651.92881468
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.90984182
21Tryptophan metabolism_Homo sapiens_hsa003801.88797642
22Nitrogen metabolism_Homo sapiens_hsa009101.85687128
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.84269145
24Salivary secretion_Homo sapiens_hsa049701.81816785
25Serotonergic synapse_Homo sapiens_hsa047261.79346219
26Amphetamine addiction_Homo sapiens_hsa050311.75390208
27Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.74601122
28Selenocompound metabolism_Homo sapiens_hsa004501.72433137
29Rheumatoid arthritis_Homo sapiens_hsa053231.65481062
30Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.62875468
31Dopaminergic synapse_Homo sapiens_hsa047281.61492659
32Olfactory transduction_Homo sapiens_hsa047401.59245971
33Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.56735833
34Vibrio cholerae infection_Homo sapiens_hsa051101.56010756
35Graft-versus-host disease_Homo sapiens_hsa053321.54734331
36Caffeine metabolism_Homo sapiens_hsa002321.54598354
37Long-term depression_Homo sapiens_hsa047301.51939393
38Taste transduction_Homo sapiens_hsa047421.50247044
39Propanoate metabolism_Homo sapiens_hsa006401.49842503
40Cholinergic synapse_Homo sapiens_hsa047251.49840039
41Insulin secretion_Homo sapiens_hsa049111.48654517
42Renin secretion_Homo sapiens_hsa049241.45978389
43African trypanosomiasis_Homo sapiens_hsa051431.43314782
44Calcium signaling pathway_Homo sapiens_hsa040201.38481038
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31208116
46Gastric acid secretion_Homo sapiens_hsa049711.30197137
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25949205
48Oxidative phosphorylation_Homo sapiens_hsa001901.25373255
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.21922183
50Oxytocin signaling pathway_Homo sapiens_hsa049211.16366349
51Regulation of autophagy_Homo sapiens_hsa041401.13530544
52Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12397435
53Aldosterone synthesis and secretion_Homo sapiens_hsa049251.11939847
54Type II diabetes mellitus_Homo sapiens_hsa049301.08570629
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08555790
56Arachidonic acid metabolism_Homo sapiens_hsa005901.08043754
57GnRH signaling pathway_Homo sapiens_hsa049121.06387477
58Peroxisome_Homo sapiens_hsa041461.04720601
59RNA polymerase_Homo sapiens_hsa030201.01781377
60Steroid hormone biosynthesis_Homo sapiens_hsa001401.01196608
61ABC transporters_Homo sapiens_hsa020101.00040105
62Alzheimers disease_Homo sapiens_hsa050100.98907850
63Phagosome_Homo sapiens_hsa041450.97795403
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.96347464
65Ovarian steroidogenesis_Homo sapiens_hsa049130.95250918
66Chemical carcinogenesis_Homo sapiens_hsa052040.95210888
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.94925711
68Sulfur metabolism_Homo sapiens_hsa009200.93276782
69Glycosaminoglycan degradation_Homo sapiens_hsa005310.92283491
70Tuberculosis_Homo sapiens_hsa051520.92100244
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.91205683
72Butanoate metabolism_Homo sapiens_hsa006500.91096438
73Cocaine addiction_Homo sapiens_hsa050300.90482293
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.87812477
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87590185
76ErbB signaling pathway_Homo sapiens_hsa040120.87078932
77Homologous recombination_Homo sapiens_hsa034400.86940938
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86236282
79Huntingtons disease_Homo sapiens_hsa050160.85719845
80Retinol metabolism_Homo sapiens_hsa008300.84924261
81Salmonella infection_Homo sapiens_hsa051320.83387327
82Cardiac muscle contraction_Homo sapiens_hsa042600.83050514
83Circadian rhythm_Homo sapiens_hsa047100.82543388
84cAMP signaling pathway_Homo sapiens_hsa040240.81248971
85Toll-like receptor signaling pathway_Homo sapiens_hsa046200.81062183
86Fanconi anemia pathway_Homo sapiens_hsa034600.80606181
87Vascular smooth muscle contraction_Homo sapiens_hsa042700.80556191
88Fatty acid elongation_Homo sapiens_hsa000620.80361554
89Glioma_Homo sapiens_hsa052140.80015530
90Melanogenesis_Homo sapiens_hsa049160.78862934
91Basal transcription factors_Homo sapiens_hsa030220.78626806
92Estrogen signaling pathway_Homo sapiens_hsa049150.75198204
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74476697
94Sulfur relay system_Homo sapiens_hsa041220.74198640
95Chemokine signaling pathway_Homo sapiens_hsa040620.73612639
96beta-Alanine metabolism_Homo sapiens_hsa004100.72990165
97Pertussis_Homo sapiens_hsa051330.72322741
98Axon guidance_Homo sapiens_hsa043600.71744562
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70949399
100Allograft rejection_Homo sapiens_hsa053300.67718899
101One carbon pool by folate_Homo sapiens_hsa006700.67509029
102Dorso-ventral axis formation_Homo sapiens_hsa043200.65245774
103Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64558600
104Gap junction_Homo sapiens_hsa045400.63513957
105Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.62915388
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62736002
107Pancreatic secretion_Homo sapiens_hsa049720.62483076
108Leishmaniasis_Homo sapiens_hsa051400.62028718
109RNA degradation_Homo sapiens_hsa030180.61633979
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61330299
111Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60223638
112NOD-like receptor signaling pathway_Homo sapiens_hsa046210.59630187
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59536452
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.59395756
115Prion diseases_Homo sapiens_hsa050200.58914159
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58471360
117Intestinal immune network for IgA production_Homo sapiens_hsa046720.58432986
118Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58361893
119Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58343802
120cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57517389
121TNF signaling pathway_Homo sapiens_hsa046680.57185233
122Steroid biosynthesis_Homo sapiens_hsa001000.56175127
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54474394
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.54236939
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53682880
126Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52951340
127Lysosome_Homo sapiens_hsa041420.52334877
128Metabolic pathways_Homo sapiens_hsa011000.52249115
129Osteoclast differentiation_Homo sapiens_hsa043800.50795101
130Asthma_Homo sapiens_hsa053100.50002547
131Mineral absorption_Homo sapiens_hsa049780.49323418
132Thyroid hormone synthesis_Homo sapiens_hsa049180.49169248
133Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48678944
134Glycerolipid metabolism_Homo sapiens_hsa005610.47963206
135Ras signaling pathway_Homo sapiens_hsa040140.47899724
136Fat digestion and absorption_Homo sapiens_hsa049750.47340267
137Staphylococcus aureus infection_Homo sapiens_hsa051500.46930416
138Choline metabolism in cancer_Homo sapiens_hsa052310.43201489
139Parkinsons disease_Homo sapiens_hsa050120.42625178
140Inositol phosphate metabolism_Homo sapiens_hsa005620.41949492
141Histidine metabolism_Homo sapiens_hsa003400.41883477
142Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41762126
143MAPK signaling pathway_Homo sapiens_hsa040100.41755562
144Rap1 signaling pathway_Homo sapiens_hsa040150.40737764
145Amoebiasis_Homo sapiens_hsa051460.39748692
146Phospholipase D signaling pathway_Homo sapiens_hsa040720.39646162
147Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34239535
148Dilated cardiomyopathy_Homo sapiens_hsa054140.34217860
149Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34045923
150Malaria_Homo sapiens_hsa051440.33803465
151VEGF signaling pathway_Homo sapiens_hsa043700.33771395
152Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.33346274
153Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33295833
154Shigellosis_Homo sapiens_hsa051310.32718962
155Glycerophospholipid metabolism_Homo sapiens_hsa005640.32358568
156Purine metabolism_Homo sapiens_hsa002300.31767658
157Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29860933
158Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.29857706

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