TMOD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)5.87012707
2desmosome organization (GO:0002934)5.51135755
3glomerular visceral epithelial cell development (GO:0072015)5.18360815
4lymph vessel development (GO:0001945)4.83407719
5hepatocyte apoptotic process (GO:0097284)4.75483195
6glomerular epithelial cell development (GO:0072310)4.56475946
7positive regulation of keratinocyte differentiation (GO:0045618)4.45892643
8bundle of His cell to Purkinje myocyte communication (GO:0086069)4.25680744
9ribosomal small subunit biogenesis (GO:0042274)4.24745789
10intestinal epithelial cell development (GO:0060576)4.21921123
11central nervous system myelination (GO:0022010)4.12753734
12axon ensheathment in central nervous system (GO:0032291)4.12753734
13hypotonic response (GO:0006971)4.10344635
14negative regulation of keratinocyte proliferation (GO:0010839)3.94539724
15glomerular basement membrane development (GO:0032836)3.94413626
16nuclear pore complex assembly (GO:0051292)3.82792460
17viral transcription (GO:0019083)3.73394288
18regulation of keratinocyte differentiation (GO:0045616)3.69871895
19establishment of skin barrier (GO:0061436)3.68092560
20iron ion import (GO:0097286)3.61945338
21positive regulation of epidermal cell differentiation (GO:0045606)3.60990851
22fatty acid elongation (GO:0030497)3.60276483
23regulation of water loss via skin (GO:0033561)3.53697477
24retina vasculature morphogenesis in camera-type eye (GO:0061299)3.50999096
25cell-substrate junction assembly (GO:0007044)3.50542856
26translational termination (GO:0006415)3.49639735
27regulation of transforming growth factor beta2 production (GO:0032909)3.44174952
28keratinocyte differentiation (GO:0030216)3.38479390
29endothelium development (GO:0003158)3.37210233
30keratinization (GO:0031424)3.33003766
31UDP-N-acetylglucosamine metabolic process (GO:0006047)3.31793055
32mammary gland epithelial cell proliferation (GO:0033598)3.31362192
33nuclear pore organization (GO:0006999)3.27013381
34regulation of hippo signaling (GO:0035330)3.26384111
35gap junction assembly (GO:0016264)3.23768785
36glomerulus development (GO:0032835)3.21099464
37skin morphogenesis (GO:0043589)3.20088185
38regulation of establishment of cell polarity (GO:2000114)3.17115239
39long-chain fatty acid biosynthetic process (GO:0042759)3.16619943
40neutrophil activation involved in immune response (GO:0002283)3.15661296
41regulation of integrin activation (GO:0033623)3.14681577
42positive regulation of Cdc42 GTPase activity (GO:0043089)3.11039441
43cotranslational protein targeting to membrane (GO:0006613)3.09769393
44mesodermal cell differentiation (GO:0048333)3.08557397
45membrane raft organization (GO:0031579)3.04777834
46keratinocyte proliferation (GO:0043616)3.04585411
47protein targeting to ER (GO:0045047)3.04358839
48virion attachment to host cell (GO:0019062)3.00512396
49adhesion of symbiont to host cell (GO:0044650)3.00512396
50SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.98757341
51regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.96866056
52vascular endothelial growth factor signaling pathway (GO:0038084)2.96590010
53establishment of protein localization to endoplasmic reticulum (GO:0072599)2.94972611
54cytoplasmic mRNA processing body assembly (GO:0033962)2.89322002
55regulation of vasculogenesis (GO:2001212)2.85378127
56positive regulation of vasculogenesis (GO:2001214)2.81840460
57protein localization to endoplasmic reticulum (GO:0070972)2.80308178
58limb bud formation (GO:0060174)2.79710124
59viral life cycle (GO:0019058)2.77042799
60pore complex assembly (GO:0046931)2.76986752
61myelination (GO:0042552)2.76770313
62regulation of integrin-mediated signaling pathway (GO:2001044)2.75201088
63ensheathment of neurons (GO:0007272)2.75095868
64axon ensheathment (GO:0008366)2.75095868
65regulation of establishment or maintenance of cell polarity (GO:0032878)2.74243061
66regulation of T cell tolerance induction (GO:0002664)2.72870408
67embryonic process involved in female pregnancy (GO:0060136)2.72275359
68positive regulation of focal adhesion assembly (GO:0051894)2.71732814
69positive regulation of cell junction assembly (GO:1901890)2.71732814
70positive regulation of epidermis development (GO:0045684)2.71263581
71peptide cross-linking (GO:0018149)2.70467782
72positive regulation of smooth muscle cell migration (GO:0014911)2.69386953
73surfactant homeostasis (GO:0043129)2.69382563
74early endosome to late endosome transport (GO:0045022)2.69070885
75negative regulation of DNA repair (GO:0045738)2.67931913
76SMAD protein complex assembly (GO:0007183)2.64929009
77renal filtration (GO:0097205)2.64341489
78positive regulation of astrocyte differentiation (GO:0048711)2.64104553
79hippo signaling (GO:0035329)2.62994127
80regulation of transforming growth factor beta1 production (GO:0032908)2.61172372
81epithelial cell-cell adhesion (GO:0090136)2.61009483
82thrombin receptor signaling pathway (GO:0070493)2.60600712
83regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.60461487
84Rap protein signal transduction (GO:0032486)2.60150378
85glomerular filtration (GO:0003094)2.59988595
86regulation of centriole replication (GO:0046599)2.59466726
87necroptotic process (GO:0070266)2.59424855
88positive regulation of endothelial cell apoptotic process (GO:2000353)2.59397909
89regulation of keratinocyte proliferation (GO:0010837)2.59197868
90dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.57339418
91regulation of metalloenzyme activity (GO:0048552)2.53935284
92cellular protein complex disassembly (GO:0043624)2.52661904
93epidermal cell differentiation (GO:0009913)2.52284207
94cytoskeleton-dependent cytokinesis (GO:0061640)2.52048100
95peptidyl-tyrosine autophosphorylation (GO:0038083)2.51480022
96positive regulation of macrophage differentiation (GO:0045651)2.50879823
97positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.50037097
98positive regulation of interleukin-17 production (GO:0032740)2.49650221
99positive regulation of interleukin-4 production (GO:0032753)2.49444365
100negative regulation of anoikis (GO:2000811)2.48749521
101lymphangiogenesis (GO:0001946)2.48394872
102neutrophil activation (GO:0042119)2.47946236
103pericardium development (GO:0060039)2.47941528
104tight junction assembly (GO:0070830)2.47725058
105histone-serine phosphorylation (GO:0035404)2.47581739
106positive regulation of adherens junction organization (GO:1903393)2.46232428
107negative regulation of fatty acid transport (GO:2000192)2.44946832
108radial glial cell differentiation (GO:0060019)2.43391372
109monocyte chemotaxis (GO:0002548)2.42556545
110regulation of cell proliferation involved in kidney development (GO:1901722)2.40862431
111wound healing, spreading of cells (GO:0044319)2.40330459
112cellular response to vitamin D (GO:0071305)2.39578567
113nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.38649784
114keratinocyte development (GO:0003334)2.38279238
115positive regulation of protein import into nucleus, translocation (GO:0033160)2.37447609
116positive regulation of pseudopodium assembly (GO:0031274)2.37202734
117cell differentiation involved in embryonic placenta development (GO:0060706)2.36737254
118protein localization to endosome (GO:0036010)2.36731621
119lung lobe morphogenesis (GO:0060463)2.36469540
120COPI coating of Golgi vesicle (GO:0048205)2.36143816
121Golgi transport vesicle coating (GO:0048200)2.36143816
122translational elongation (GO:0006414)2.36050190
123cell adhesion mediated by integrin (GO:0033627)2.35949600
124mitotic sister chromatid cohesion (GO:0007064)2.35389134
125protein neddylation (GO:0045116)2.34323126
126regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.34233451
127negative regulation of axon guidance (GO:1902668)2.32178737
128regulation of epidermal cell differentiation (GO:0045604)2.30446198
129negative regulation of protein localization to cell surface (GO:2000009)2.29798176
130heterotypic cell-cell adhesion (GO:0034113)2.29301645
131cellular response to ethanol (GO:0071361)2.28905419
132regulation of focal adhesion assembly (GO:0051893)2.28279333
133regulation of cell-substrate junction assembly (GO:0090109)2.28279333
134ear development (GO:0043583)2.27147260
135lateral sprouting from an epithelium (GO:0060601)2.26513761
136platelet-derived growth factor receptor signaling pathway (GO:0048008)2.26115100
137negative regulation of axon extension involved in axon guidance (GO:0048843)2.26087753
138granulocyte activation (GO:0036230)2.25682222
139wound healing, spreading of epidermal cells (GO:0035313)2.25289310
140chemical homeostasis within a tissue (GO:0048875)2.24722235
141regulation of apoptotic process involved in morphogenesis (GO:1902337)2.23179729
142mitotic cytokinesis (GO:0000281)2.23093351
143regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.21965147
144protein targeting to membrane (GO:0006612)2.21684259
145negative regulation of neurotransmitter secretion (GO:0046929)2.21582265
146ER overload response (GO:0006983)2.20206969
147regulation of T cell migration (GO:2000404)2.19418419
148protein localization to microtubule (GO:0035372)2.18967115
149definitive hemopoiesis (GO:0060216)2.18787553
150positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.18590755
151regulation of transforming growth factor beta production (GO:0071634)2.18452723
152membrane protein ectodomain proteolysis (GO:0006509)2.17972447
153amyloid precursor protein metabolic process (GO:0042982)2.16430864
154regulation of adherens junction organization (GO:1903391)2.16358958
155phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.16242092
156positive regulation of T cell chemotaxis (GO:0010820)2.15782418
157regulation of T cell chemotaxis (GO:0010819)2.15782418
158positive regulation of immune response to tumor cell (GO:0002839)2.15473191
159regulation of immune response to tumor cell (GO:0002837)2.15473191
160regulation of response to tumor cell (GO:0002834)2.15473191
161positive regulation of response to tumor cell (GO:0002836)2.15473191
162positive regulation of interleukin-8 secretion (GO:2000484)2.14942441
163positive regulation of monocyte chemotaxis (GO:0090026)2.14570191
164positive regulation of odontogenesis (GO:0042482)2.14503977
165leukocyte aggregation (GO:0070486)2.14330565
166neural crest cell development (GO:0014032)2.13250308
167establishment of endothelial barrier (GO:0061028)2.13220247
168mesenchymal cell development (GO:0014031)2.12159337
169positive regulation of lipid kinase activity (GO:0090218)2.12118135
170adhesion of symbiont to host (GO:0044406)2.12107401
171sphingoid metabolic process (GO:0046519)2.11357803
172regulation of interleukin-4 production (GO:0032673)2.11298060
173antigen processing and presentation of endogenous antigen (GO:0019883)2.10755688
174T-helper 1 type immune response (GO:0042088)2.09962776
175positive regulation of interleukin-2 production (GO:0032743)2.09563090
176positive regulation of T cell migration (GO:2000406)2.09192903
177positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.09172955
178regulation of tolerance induction (GO:0002643)2.08723314
179ribosomal small subunit assembly (GO:0000028)2.07245657
180T-helper cell differentiation (GO:0042093)2.06650791
181CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.06650791
182regulation of interleukin-17 production (GO:0032660)2.06112180
183leukocyte migration involved in inflammatory response (GO:0002523)2.04832486
184positive regulation of alpha-beta T cell proliferation (GO:0046641)2.04766986
185regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.04449200

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.18062255
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.32796757
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.47639854
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.96551035
5TRIM28_21343339_ChIP-Seq_HEK293_Human3.69701502
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.66576166
7WT1_19549856_ChIP-ChIP_CCG9911_Human3.04364068
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.86315858
9IRF8_21731497_ChIP-ChIP_J774_Mouse2.47502183
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.43805398
11ESR1_20079471_ChIP-ChIP_T-47D_Human2.42088195
12GATA1_22025678_ChIP-Seq_K562_Human2.38674428
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.29266811
14IRF8_22096565_ChIP-ChIP_GC-B_Human2.27979949
15* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.26787453
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.21197881
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.20409718
18HIF1A_21447827_ChIP-Seq_MCF-7_Human2.15640938
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.13560942
20AR_21909140_ChIP-Seq_LNCAP_Human2.05928794
21STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.03746689
22FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human2.02163973
23* BRD4_25478319_ChIP-Seq_HGPS_Human1.98531286
24AHR_22903824_ChIP-Seq_MCF-7_Human1.98394824
25SMAD_19615063_ChIP-ChIP_OVARY_Human1.96764079
26CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.91179694
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.90603513
28KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.90573728
29IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.80603524
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.80241746
31RUNX_20019798_ChIP-Seq_JUKART_Human1.79463304
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73755127
33RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.73478195
34CJUN_26792858_Chip-Seq_BT549_Human1.72945574
35GATA2_21666600_ChIP-Seq_HMVEC_Human1.72895056
36IRF8_27001747_Chip-Seq_BMDM_Mouse1.66319892
37E2F7_22180533_ChIP-Seq_HELA_Human1.65318867
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64385580
39* SOX2_20726797_ChIP-Seq_SW620_Human1.63392047
40CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.61973627
41ARNT_22903824_ChIP-Seq_MCF-7_Human1.56359384
42NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.55552545
43NRF2_20460467_ChIP-Seq_MEFs_Mouse1.55552545
44CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.55485109
45TAF15_26573619_Chip-Seq_HEK293_Human1.53222715
46SOX2_27498859_Chip-Seq_STOMACH_Mouse1.52874436
47FOXO3_23340844_ChIP-Seq_DLD1_Human1.51886950
48* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49583305
49PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.49522772
50STAT4_19710469_ChIP-ChIP_TH1__Mouse1.47803094
51TP53_18474530_ChIP-ChIP_U2OS_Human1.46577236
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.45484111
53ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.44674678
54GATA6_25053715_ChIP-Seq_YYC3_Human1.42427387
55SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.41781891
56EP300_21415370_ChIP-Seq_HL-1_Mouse1.38080450
57BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37878943
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37564187
59PPAR_26484153_Chip-Seq_NCI-H1993_Human1.37538862
60GATA4_25053715_ChIP-Seq_YYC3_Human1.35997945
61FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.35676346
62* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.35676247
63* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.35676247
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34557765
65GATA3_24758297_ChIP-Seq_MCF-7_Human1.34434332
66* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34433033
67PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.33609129
68EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.32302799
69* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.32185651
70VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.31417763
71Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.30988529
72SOX9_24532713_ChIP-Seq_HFSC_Mouse1.28820608
73KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.28258730
74AR_21572438_ChIP-Seq_LNCaP_Human1.25005960
75RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25003128
76VDR_22108803_ChIP-Seq_LS180_Human1.23714009
77VDR_24787735_ChIP-Seq_THP-1_Human1.23126759
78KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.21922879
79TP53_16413492_ChIP-PET_HCT116_Human1.20746301
80ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19749544
81ELK1_19687146_ChIP-ChIP_HELA_Human1.19594098
82NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.18771750
83EED_16625203_ChIP-ChIP_MESCs_Mouse1.18044156
84MYB_21317192_ChIP-Seq_ERMYB_Mouse1.18021904
85PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.17566883
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.16004720
87CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.14736327
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14041510
89FUS_26573619_Chip-Seq_HEK293_Human1.13614522
90SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.11671512
91ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10543136
92POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09952421
93TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.09480353
94SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.09342058
95ATF3_27146783_Chip-Seq_COLON_Human1.09074916
96PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.08871399
97* EWS_26573619_Chip-Seq_HEK293_Human1.08857573
98SMAD3_21741376_ChIP-Seq_EPCs_Human1.07072876
99CBX2_27304074_Chip-Seq_ESCs_Mouse1.05544428
100P63_26484246_Chip-Seq_KERATINOCYTES_Human1.04784096
101CLOCK_20551151_ChIP-Seq_293T_Human1.04721231
102UBF1/2_26484160_Chip-Seq_HMECs_Human1.04307892
103STAT6_21828071_ChIP-Seq_BEAS2B_Human1.04247261
104* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.04082469
105P300_19829295_ChIP-Seq_ESCs_Human1.03561708
106SALL4_18804426_ChIP-ChIP_XEN_Mouse1.02749741
107EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02743547
108* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02415316
109ELF5_23300383_ChIP-Seq_T47D_Human1.02039231
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01912617
111* ER_23166858_ChIP-Seq_MCF-7_Human1.01866878
112ESR1_21235772_ChIP-Seq_MCF-7_Human1.01700810
113* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.01068231
114SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.99965456
115CDX2_20551321_ChIP-Seq_CACO-2_Human0.98521734
116BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98391588
117FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.97316014
118* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97240131
119JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97191220
120TCF4_18268006_ChIP-ChIP_LS174T_Human0.95944978
121KLF5_25053715_ChIP-Seq_YYC3_Human0.95944536
122JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95734133
123PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.95517796
124E2F4_17652178_ChIP-ChIP_JURKAT_Human0.95448816
125RUNX1_27514584_Chip-Seq_MCF-7_Human0.95242406
126* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94992516
127ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.94802655
128GATA2_19941826_ChIP-Seq_K562_Human0.94386800
129TP63_23658742_ChIP-Seq_EP156T_Human0.94062747
130ESR2_21235772_ChIP-Seq_MCF-7_Human0.93448496
131SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.93060439
132RARG_19884340_ChIP-ChIP_MEFs_Mouse0.92809220
133PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92420646
134BRD4_27068464_Chip-Seq_AML-cells_Mouse0.91896135
135FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.91698104
136NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.91221994
137STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.90691918
138PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.90256512
139STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.89167923
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.88531539
141CDX2_22108803_ChIP-Seq_LS180_Human0.87739261
142SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.85633954
143SCL_19346495_ChIP-Seq_HPC-7_Human0.85244109
144TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.82825637
145SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.81911421
146MYB_26560356_Chip-Seq_TH2_Human0.81412349

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.00512169
2MP0002877_abnormal_melanocyte_morpholog3.81239880
3MP0004272_abnormal_basement_membrane3.18442305
4MP0010352_gastrointestinal_tract_polyps3.14984354
5MP0001879_abnormal_lymphatic_vessel3.14085061
6MP0003705_abnormal_hypodermis_morpholog3.12002105
7MP0008438_abnormal_cutaneous_collagen2.85570616
8MP0003724_increased_susceptibility_to2.84572790
9MP0009379_abnormal_foot_pigmentation2.76026068
10MP0005623_abnormal_meninges_morphology2.62692870
11MP0000383_abnormal_hair_follicle2.50859755
12MP0002009_preneoplasia2.41818060
13MP0009780_abnormal_chondrocyte_physiolo2.26339884
14MP0004381_abnormal_hair_follicle2.22862147
15MP0000920_abnormal_myelination2.13791691
16MP0010678_abnormal_skin_adnexa2.11062578
17MP0002148_abnormal_hypersensitivity_rea2.05982543
18MP0006054_spinal_hemorrhage2.04323167
19MP0005409_darkened_coat_color2.02922008
20MP0008057_abnormal_DNA_replication2.01572660
21MP0000569_abnormal_digit_pigmentation2.01296959
22MP0005275_abnormal_skin_tensile2.00019681
23MP0005076_abnormal_cell_differentiation1.98154265
24MP0004264_abnormal_extraembryonic_tissu1.95215658
25MP0002166_altered_tumor_susceptibility1.92120581
26MP0001835_abnormal_antigen_presentation1.89356331
27MP0001346_abnormal_lacrimal_gland1.83571629
28MP0001790_abnormal_immune_system1.82981372
29MP0005387_immune_system_phenotype1.82981372
30MP0005171_absent_coat_pigmentation1.80671005
31MP0005000_abnormal_immune_tolerance1.76575237
32MP0002295_abnormal_pulmonary_circulatio1.76350028
33MP0003950_abnormal_plasma_membrane1.75814313
34MP0005671_abnormal_response_to1.74394689
35MP0002796_impaired_skin_barrier1.74008655
36MP0010368_abnormal_lymphatic_system1.73715282
37MP0001958_emphysema1.69925479
38MP0009785_altered_susceptibility_to1.67533274
39MP0003136_yellow_coat_color1.62859515
40MP0003300_gastrointestinal_ulcer1.61579711
41MP0001851_eye_inflammation1.56988454
42MP0003941_abnormal_skin_development1.56480021
43MP0001800_abnormal_humoral_immune1.50119362
44MP0002452_abnormal_antigen_presenting1.49449435
45MP0002006_tumorigenesis1.47446388
46MP0000579_abnormal_nail_morphology1.47197492
47MP0005025_abnormal_response_to1.47010302
48MP0002933_joint_inflammation1.46615135
49MP0005167_abnormal_blood-brain_barrier1.46071713
50MP0005464_abnormal_platelet_physiology1.45870416
51MP0003828_pulmonary_edema1.43221180
52MP0000465_gastrointestinal_hemorrhage1.42059512
53MP0005503_abnormal_tendon_morphology1.41784765
54MP0002723_abnormal_immune_serum1.41008292
55MP0002419_abnormal_innate_immunity1.40957773
56MP0000427_abnormal_hair_cycle1.39775281
57MP0002098_abnormal_vibrissa_morphology1.39305178
58MP0005408_hypopigmentation1.37406328
59MP0002420_abnormal_adaptive_immunity1.36166148
60MP0009384_cardiac_valve_regurgitation1.35550656
61MP0001819_abnormal_immune_cell1.35459058
62MP0003191_abnormal_cellular_cholesterol1.32210099
63MP0002060_abnormal_skin_morphology1.30535205
64MP0004782_abnormal_surfactant_physiolog1.28964810
65MP0000685_abnormal_immune_system1.28887992
66MP0003091_abnormal_cell_migration1.26411558
67MP0006082_CNS_inflammation1.25372467
68MP0000647_abnormal_sebaceous_gland1.24816464
69MP0005164_abnormal_response_to1.23856563
70MP0003453_abnormal_keratinocyte_physiol1.21724123
71MP0000537_abnormal_urethra_morphology1.21251504
72MP0002282_abnormal_trachea_morphology1.18070822
73MP0000627_abnormal_mammary_gland1.17306847
74MP0004947_skin_inflammation1.17260200
75MP0003279_aneurysm1.17064010
76MP0009697_abnormal_copulation1.16516632
77MP0003448_altered_tumor_morphology1.16394169
78MP0001216_abnormal_epidermal_layer1.15092941
79MP0000762_abnormal_tongue_morphology1.14975397
80MP0001533_abnormal_skeleton_physiology1.13300699
81MP0009333_abnormal_splenocyte_physiolog1.10570776
82MP0001243_abnormal_dermal_layer1.09786792
83MP0004233_abnormal_muscle_weight1.07717663
84MP0004957_abnormal_blastocyst_morpholog1.06819945
85MP0005501_abnormal_skin_physiology1.03743587
86MP0002405_respiratory_system_inflammati1.02836286
87MP0003436_decreased_susceptibility_to1.02676528
88MP0001191_abnormal_skin_condition1.01344798
89MP0003303_peritoneal_inflammation1.00974500
90MP0002086_abnormal_extraembryonic_tissu1.00729482
91MP0000858_altered_metastatic_potential1.00709727
92MP0000767_abnormal_smooth_muscle1.00276985
93MP0004808_abnormal_hematopoietic_stem0.99908251
94MP0001873_stomach_inflammation0.97878974
95MP0000249_abnormal_blood_vessel0.97392185
96MP0003566_abnormal_cell_adhesion0.97234400
97MP0005257_abnormal_intraocular_pressure0.95287483
98MP0003763_abnormal_thymus_physiology0.95275423
99MP0002133_abnormal_respiratory_system0.95206583
100MP0005388_respiratory_system_phenotype0.95206583
101MP0009053_abnormal_anal_canal0.95134160
102MP0005621_abnormal_cell_physiology0.94347239
103MP0001849_ear_inflammation0.93432338
104MP0000377_abnormal_hair_follicle0.92631258
105MP0005165_increased_susceptibility_to0.92235366
106MP0000516_abnormal_urinary_system0.91469347
107MP0005367_renal/urinary_system_phenotyp0.91469347
108MP0010771_integument_phenotype0.90376785
109MP0002998_abnormal_bone_remodeling0.89514534
110MP0000716_abnormal_immune_system0.89150005
111MP0001661_extended_life_span0.88325882
112MP0000467_abnormal_esophagus_morphology0.88018414
113MP0010307_abnormal_tumor_latency0.87757991
114MP0010155_abnormal_intestine_physiology0.86936296
115MP0003690_abnormal_glial_cell0.86617509
116MP0001905_abnormal_dopamine_level0.86234971
117MP0004883_abnormal_blood_vessel0.85574725
118MP0000372_irregular_coat_pigmentation0.84903260
119MP0005390_skeleton_phenotype0.84782430
120MP0009931_abnormal_skin_appearance0.84505212
121MP0005508_abnormal_skeleton_morphology0.84095135
122MP0001542_abnormal_bone_strength0.83728995
123MP0009250_abnormal_appendicular_skeleto0.83527974
124MP0003806_abnormal_nucleotide_metabolis0.82883208
125MP0000343_altered_response_to0.82698330
126MP0002254_reproductive_system_inflammat0.82183954
127MP0003656_abnormal_erythrocyte_physiolo0.81424563
128MP0002896_abnormal_bone_mineralization0.81111670
129MP0005023_abnormal_wound_healing0.81097972
130MP0008004_abnormal_stomach_pH0.80889804
131MP0003045_fibrosis0.78915715
132MP0002163_abnormal_gland_morphology0.78640187
133MP0009278_abnormal_bone_marrow0.78566069
134MP0001727_abnormal_embryo_implantation0.77929183
135MP0003937_abnormal_limbs/digits/tail_de0.76429999
136MP0001881_abnormal_mammary_gland0.75810562
137MP0002396_abnormal_hematopoietic_system0.75524687
138MP0004185_abnormal_adipocyte_glucose0.74928971
139MP0003183_abnormal_peptide_metabolism0.70276415
140MP0002088_abnormal_embryonic_growth/wei0.65597509
141MP0001348_abnormal_lacrimal_gland0.65411938
142MP0003984_embryonic_growth_retardation0.64987411
143MP0005360_urolithiasis0.62227405
144MP0002332_abnormal_exercise_endurance0.61941829
145MP0003077_abnormal_cell_cycle0.61080029
146MP0000350_abnormal_cell_proliferation0.60966841
147MP0000371_diluted_coat_color0.60031420
148MP0005384_cellular_phenotype0.59817525
149MP0001697_abnormal_embryo_size0.59739441
150MP0005380_embryogenesis_phenotype0.59527829
151MP0001672_abnormal_embryogenesis/_devel0.59527829

Predicted human phenotypes

RankGene SetZ-score
1Parakeratosis (HP:0001036)5.56431058
2Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.20428743
3Milia (HP:0001056)3.61000529
4Congenital, generalized hypertrichosis (HP:0004540)3.30083880
5Abnormality of nail color (HP:0100643)3.21325946
6Increased mean platelet volume (HP:0011877)3.13714833
7Plantar hyperkeratosis (HP:0007556)3.12600863
8Right ventricular cardiomyopathy (HP:0011663)3.12006293
9Aplasia cutis congenita (HP:0001057)3.06891342
10Congenital ichthyosiform erythroderma (HP:0007431)3.04693353
11Absent frontal sinuses (HP:0002688)3.02559705
12Alopecia of scalp (HP:0002293)3.01071195
13Abnormality of cells of the erythroid lineage (HP:0012130)2.96330113
14Hypoplasia of the iris (HP:0007676)2.92162480
15Premature rupture of membranes (HP:0001788)2.86956093
16Curly hair (HP:0002212)2.80844693
17Ankyloglossia (HP:0010296)2.79796827
18Stenosis of the external auditory canal (HP:0000402)2.79255519
19Osteolytic defects of the hand bones (HP:0009699)2.77543727
20Osteolytic defects of the phalanges of the hand (HP:0009771)2.77543727
21Abnormal platelet volume (HP:0011876)2.76758537
22Chronic otitis media (HP:0000389)2.71822845
23Spontaneous hematomas (HP:0007420)2.69508373
24Recurrent abscess formation (HP:0002722)2.68390412
25Sensory axonal neuropathy (HP:0003390)2.66238328
26Abnormality of the axillary hair (HP:0100134)2.65958950
27Abnormality of secondary sexual hair (HP:0009888)2.65958950
28Subacute progressive viral hepatitis (HP:0006572)2.62050835
29Abnormal hemoglobin (HP:0011902)2.61323286
30Nail dystrophy (HP:0008404)2.61177764
31Papillary thyroid carcinoma (HP:0002895)2.60065438
32Abnormality of oral frenula (HP:0000190)2.59135317
33Palmoplantar hyperkeratosis (HP:0000972)2.57149603
34Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.55165198
35Esophageal atresia (HP:0002032)2.51509200
36Neurofibrillary tangles (HP:0002185)2.46334985
37Thick nail (HP:0001805)2.45208978
38Spinal cord lesions (HP:0100561)2.44974779
39Syringomyelia (HP:0003396)2.44974779
40Reticulocytopenia (HP:0001896)2.44114864
41Lip pit (HP:0100267)2.41655376
42Abnormality of the frontal sinuses (HP:0002687)2.41060743
43Palmar hyperkeratosis (HP:0010765)2.40607707
44Abnormal number of erythroid precursors (HP:0012131)2.35286841
45Mesangial abnormality (HP:0001966)2.32740625
46Xerostomia (HP:0000217)2.32034183
47Hypoproteinemia (HP:0003075)2.31955536
48Menorrhagia (HP:0000132)2.31898247
49Degeneration of the lateral corticospinal tracts (HP:0002314)2.31451870
50Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.31451870
51Hypoplasia of dental enamel (HP:0006297)2.30927760
52Short nail (HP:0001799)2.30807409
53Focal segmental glomerulosclerosis (HP:0000097)2.29601609
54Abnormal albumin level (HP:0012116)2.26958446
55Hypoalbuminemia (HP:0003073)2.26958446
56Hypotrichosis (HP:0001006)2.25821856
57Cardiovascular calcification (HP:0011915)2.23708858
58Macrocytic anemia (HP:0001972)2.22328922
59Aortic aneurysm (HP:0004942)2.21863425
60Chin dimple (HP:0010751)2.20024191
61Abnormality of macrophages (HP:0004311)2.19301307
62Short hallux (HP:0010109)2.18111311
63Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.17694434
64Recurrent bacterial skin infections (HP:0005406)2.17200396
65Selective tooth agenesis (HP:0001592)2.16255023
66Cupped ear (HP:0000378)2.15949970
67Fragile skin (HP:0001030)2.15888367
68Coarse hair (HP:0002208)2.15847946
69Premature skin wrinkling (HP:0100678)2.15008224
70Autoimmune hemolytic anemia (HP:0001890)2.14633962
71Broad face (HP:0000283)2.12980168
72Gastrointestinal stroma tumor (HP:0100723)2.11147598
73Patchy hypopigmentation of hair (HP:0011365)2.10873157
74Micronodular cirrhosis (HP:0001413)2.10776934
75Natal tooth (HP:0000695)2.10011669
76Ridged nail (HP:0001807)2.09930964
77Stomach cancer (HP:0012126)2.06361728
78Pulmonary artery stenosis (HP:0004415)2.05963796
79Mitral stenosis (HP:0001718)2.05641286
80Hepatosplenomegaly (HP:0001433)2.05480508
81Hypoplastic labia majora (HP:0000059)2.04499753
82Anhidrosis (HP:0000970)2.04452584
83Entropion (HP:0000621)2.03933958
84Deep philtrum (HP:0002002)2.03836259
85Protrusio acetabuli (HP:0003179)2.03581478
86White forelock (HP:0002211)2.03382325
87Flat acetabular roof (HP:0003180)2.02349056
88Stomatitis (HP:0010280)1.99994266
89Abnormality of the phalanges of the 2nd finger (HP:0009541)1.99649417
90Fragile nails (HP:0001808)1.99144678
91Woolly hair (HP:0002224)1.98910229
92Aortic dissection (HP:0002647)1.98079463
93Interstitial pulmonary disease (HP:0006530)1.97988167
94Hematochezia (HP:0002573)1.97750636
95Absent hand (HP:0004050)1.97189837
96Eczematoid dermatitis (HP:0000976)1.96920336
97Vascular calcification (HP:0004934)1.96749340
98Abnormality of the 2nd finger (HP:0004100)1.95806977
99Thyroid carcinoma (HP:0002890)1.95715096
100Tibial bowing (HP:0002982)1.95448273
101Delayed cranial suture closure (HP:0000270)1.95307323
102Arterial tortuosity (HP:0005116)1.95274320
103Septate vagina (HP:0001153)1.94351664
104Corneal erosion (HP:0200020)1.94290997
105Ectropion (HP:0000656)1.94280194
106Pustule (HP:0200039)1.93440443
107Spondylolisthesis (HP:0003302)1.92868240
108Cheilitis (HP:0100825)1.91979351
109Chromsome breakage (HP:0040012)1.91421445
110Poikiloderma (HP:0001029)1.91405421
111Blepharitis (HP:0000498)1.91071974
112Acute myeloid leukemia (HP:0004808)1.90490069
113Cerebral hemorrhage (HP:0001342)1.90125932
114Vasculitis (HP:0002633)1.88818964
115Chronic obstructive pulmonary disease (HP:0006510)1.88790468
116Obstructive lung disease (HP:0006536)1.88790468
117Vascular tortuosity (HP:0004948)1.87942149
118Metaphyseal dysplasia (HP:0100255)1.87593432
119Dilatation of the ascending aorta (HP:0005111)1.86855057
120Prolonged bleeding time (HP:0003010)1.85602432
121Nasolacrimal duct obstruction (HP:0000579)1.84921903
122Elevated erythrocyte sedimentation rate (HP:0003565)1.84763048
123Erythroderma (HP:0001019)1.84434965
124Partial duplication of thumb phalanx (HP:0009944)1.83880700
125Agammaglobulinemia (HP:0004432)1.83416373
126Tubular atrophy (HP:0000092)1.82389600
127Venous abnormality (HP:0002624)1.82361677
128Wormian bones (HP:0002645)1.82272691
129Aplasia/Hypoplasia of the hallux (HP:0008362)1.81965479
130Broad metatarsal (HP:0001783)1.81848640
131Eosinophilia (HP:0001880)1.81658045
132Onycholysis (HP:0001806)1.81402610
133Abnormality of the nasal septum (HP:0000419)1.81269619
134Concave nail (HP:0001598)1.81083601
135Thin bony cortex (HP:0002753)1.80660051
136Cellulitis (HP:0100658)1.79894326
137Periodontitis (HP:0000704)1.78504851
138Fair hair (HP:0002286)1.78065799
139Abnormality of the labia majora (HP:0012881)1.77650861
140Mitral valve prolapse (HP:0001634)1.77580777
141Abnormality of the gastric mucosa (HP:0004295)1.77462535
142Partial duplication of the phalanx of hand (HP:0009999)1.77257239
143Chromosomal breakage induced by crosslinking agents (HP:0003221)1.77235105
144Abnormal auditory evoked potentials (HP:0006958)1.76949743
145Pallor (HP:0000980)1.75687642
146Purpura (HP:0000979)1.74812764
147Cerebral inclusion bodies (HP:0100314)1.74137836
148Generalized hypopigmentation of hair (HP:0011358)1.73856441
149Conjugated hyperbilirubinemia (HP:0002908)1.73449925
150Hoarse voice (HP:0001609)1.72883478
151Bladder neoplasm (HP:0009725)1.72446641
152Bladder carcinoma (HP:0002862)1.72446641
153Atrophic scars (HP:0001075)1.71288807
154Optic neuritis (HP:0100653)1.71179723
155Retrobulbar optic neuritis (HP:0100654)1.71179723
156Seborrheic dermatitis (HP:0001051)1.71055514
157Cystic hygroma (HP:0000476)1.70670950
158Granulocytopenia (HP:0001913)1.70497716
159Transitional cell carcinoma of the bladder (HP:0006740)1.70400869
160Vertebral arch anomaly (HP:0008438)1.70212784
161Asymmetry of the thorax (HP:0001555)1.70152235
162Fused cervical vertebrae (HP:0002949)1.69872121
163Increased IgM level (HP:0003496)1.69515481
164Abnormality of T cell number (HP:0011839)1.69068222
165Abnormal blistering of the skin (HP:0008066)1.68974527
166Recurrent skin infections (HP:0001581)1.68178078
167Erythema (HP:0010783)1.66955522
168Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.66628365
169Overfolded helix (HP:0000396)1.66118994
170Anteriorly placed anus (HP:0001545)1.66102717
171T lymphocytopenia (HP:0005403)1.66053075
172Abnormality of the common coagulation pathway (HP:0010990)1.65872597
173Leukocytosis (HP:0001974)1.65262749
174Bilateral sensorineural hearing impairment (HP:0008619)1.64698464
175Neonatal respiratory distress (HP:0002643)1.63803165
176Corneal dystrophy (HP:0001131)1.63687910
177Myocardial infarction (HP:0001658)1.63676052
178Recurrent bronchitis (HP:0002837)1.63519416
179Glomerulosclerosis (HP:0000096)1.63493150
180Breast hypoplasia (HP:0003187)1.61224207
181Melanocytic nevus (HP:0000995)1.60888629
182Reduced subcutaneous adipose tissue (HP:0003758)1.60746475

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST44.50296480
2STK393.89700675
3EPHB12.66115759
4KDR2.54105421
5TIE12.53859534
6PBK2.53384210
7LATS12.28458788
8MAP3K122.24032572
9BCR2.20125575
10OXSR12.16354153
11SCYL22.14596226
12TGFBR22.06926024
13STK101.92423227
14EIF2AK11.87236049
15CDK121.86071337
16BLK1.85290598
17FGR1.81194381
18FGFR21.75191714
19TRPM71.70791332
20MAP3K141.68592110
21RPS6KB21.67765177
22LRRK21.66164971
23IRAK31.65226818
24NEK91.61930619
25ITK1.59407054
26ACVR1B1.56116107
27EPHB21.56033062
28MAP4K11.55576480
29FRK1.53946446
30ERBB41.51303955
31MAP3K21.50015361
32MET1.48837638
33BRSK21.48815465
34PTK21.45794617
35PDGFRA1.42592454
36WNK41.41384722
37PIM21.39879059
38MAPKAPK51.34567662
39GRK71.30077052
40PKN21.29394354
41EIF2AK31.27835563
42CLK11.26811583
43TXK1.25826458
44CSK1.25506742
45MYLK1.23666707
46IKBKB1.22268795
47BMPR1B1.20956939
48PKN11.20040605
49TGFBR11.19086466
50KIT1.18597446
51LATS21.17808831
52NUAK11.16764389
53TEC1.15981126
54GRK11.15802407
55PRKCQ1.14735868
56ROCK21.08547144
57NME21.08117115
58STK241.03407928
59IRAK41.01523473
60ERBB31.01415957
61LCK1.00866278
62EPHA31.00077093
63CDK80.99417758
64STK38L0.99136851
65MAPK150.98129399
66PTK2B0.96238825
67CSNK1A1L0.96186236
68TYK20.93449688
69PDGFRB0.93414739
70MAPKAPK30.93321716
71SIK10.92336912
72TTN0.91188860
73SIK30.89934356
74EEF2K0.89862973
75RIPK40.88536364
76NLK0.88520244
77FER0.87787752
78IKBKE0.85042722
79FES0.83367879
80CSNK1G30.82132233
81BTK0.81742864
82MST1R0.81594009
83BMPR20.80861742
84CSF1R0.80740332
85MAP3K30.80279497
86BMX0.79049709
87TRIB30.76899511
88FLT30.75988833
89TBK10.75286443
90PRKCE0.75041158
91STK30.74670510
92CSNK1G10.74525661
93CHUK0.74407455
94JAK30.73649423
95HCK0.73616299
96CDK60.73387326
97NEK20.73269816
98LYN0.72888839
99KSR10.68043511
100ILK0.67924383
101INSR0.67820018
102ADRBK10.67435043
103MAP3K130.66409145
104YES10.65747892
105WNK10.65672777
106PIK3CG0.65442362
107RPS6KA50.65166222
108JAK10.64335673
109ABL10.63759083
110TAOK30.63674669
111GSK3A0.62273296
112PRKD10.61356307
113PAK30.60195443
114MAP3K90.59388901
115MTOR0.58993581
116IGF1R0.57319438
117ZAP700.57305320
118MAP2K20.57071471
119SYK0.57030798
120FYN0.56976026
121MAP2K10.56873697
122CAMK2B0.56697952
123ADRBK20.56480468
124PNCK0.55366847
125PIK3CA0.55180776
126TNIK0.53596797
127MKNK10.53317878
128PIM10.51192911
129EIF2AK20.50836323
130CAMKK20.50602597
131LIMK10.50247255
132AKT30.50198047
133GRK60.49857981
134PAK40.48514892
135SGK30.47730488
136MARK30.47301811
137STK380.46913933
138FGFR30.46379217
139VRK10.46228521
140PAK20.45828020
141IRAK10.45646362
142TAF10.45190408
143TRIM280.44610981
144NTRK10.44581411
145EGFR0.44390007
146PTK60.44175708
147EPHA20.43403215
148MOS0.43200943
149MELK0.42790472
150MAPKAPK20.42753704
151NEK60.42753485
152RPS6KA40.39991852
153STK40.39155136
154MAP3K60.38778423
155FGFR10.38543826
156MAP3K80.38091495
157TTK0.37795043
158CDK90.36668425
159AURKB0.35546379

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030102.83728869
2Graft-versus-host disease_Homo sapiens_hsa053322.49101223
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.23124521
4Allograft rejection_Homo sapiens_hsa053302.07110797
5Thyroid cancer_Homo sapiens_hsa052162.06990260
6ECM-receptor interaction_Homo sapiens_hsa045121.97252506
7Malaria_Homo sapiens_hsa051441.94590537
8Autoimmune thyroid disease_Homo sapiens_hsa053201.79491778
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.76384044
10Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.75694061
11Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.73860906
12Hematopoietic cell lineage_Homo sapiens_hsa046401.69098290
13Rheumatoid arthritis_Homo sapiens_hsa053231.63685916
14Leukocyte transendothelial migration_Homo sapiens_hsa046701.61391207
15Chronic myeloid leukemia_Homo sapiens_hsa052201.61270769
16Primary immunodeficiency_Homo sapiens_hsa053401.58510559
17Bladder cancer_Homo sapiens_hsa052191.55054107
18Fatty acid elongation_Homo sapiens_hsa000621.52607820
19Sphingolipid metabolism_Homo sapiens_hsa006001.48234921
20Protein export_Homo sapiens_hsa030601.45547425
21Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43521909
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.42826366
23Intestinal immune network for IgA production_Homo sapiens_hsa046721.41786169
24Viral myocarditis_Homo sapiens_hsa054161.41620715
25Steroid biosynthesis_Homo sapiens_hsa001001.39592142
26Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.37789520
27Axon guidance_Homo sapiens_hsa043601.37223310
28Ether lipid metabolism_Homo sapiens_hsa005651.36853700
29Leishmaniasis_Homo sapiens_hsa051401.35361122
30Oxidative phosphorylation_Homo sapiens_hsa001901.30307593
31p53 signaling pathway_Homo sapiens_hsa041151.27840415
32Measles_Homo sapiens_hsa051621.23026686
33B cell receptor signaling pathway_Homo sapiens_hsa046621.22450159
34Proteasome_Homo sapiens_hsa030501.22325939
35T cell receptor signaling pathway_Homo sapiens_hsa046601.22091476
36Focal adhesion_Homo sapiens_hsa045101.19966839
37AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.18240404
38Non-small cell lung cancer_Homo sapiens_hsa052231.17793056
39Salmonella infection_Homo sapiens_hsa051321.17289381
40Pertussis_Homo sapiens_hsa051331.16485143
41Toxoplasmosis_Homo sapiens_hsa051451.14730071
42Endometrial cancer_Homo sapiens_hsa052131.13101535
43Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.12778033
44Osteoclast differentiation_Homo sapiens_hsa043801.12637729
45Small cell lung cancer_Homo sapiens_hsa052221.10637746
46Adherens junction_Homo sapiens_hsa045201.10151488
47Shigellosis_Homo sapiens_hsa051311.09715034
48Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.09459424
49Asthma_Homo sapiens_hsa053101.08295325
50Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.07771826
51Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.06892169
52Viral carcinogenesis_Homo sapiens_hsa052031.06267410
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05867459
54Antigen processing and presentation_Homo sapiens_hsa046121.03624160
55Amoebiasis_Homo sapiens_hsa051461.03605197
56NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02904706
57Alzheimers disease_Homo sapiens_hsa050101.01883509
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.01223806
59Renal cell carcinoma_Homo sapiens_hsa052111.00756334
60Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.00024298
61Acute myeloid leukemia_Homo sapiens_hsa052210.99788162
62Platelet activation_Homo sapiens_hsa046110.98224085
63Phagosome_Homo sapiens_hsa041450.95619681
64African trypanosomiasis_Homo sapiens_hsa051430.95279653
65Regulation of actin cytoskeleton_Homo sapiens_hsa048100.91825696
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91483131
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.90768375
68Melanoma_Homo sapiens_hsa052180.90374981
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.89477505
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89231362
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88495257
72Hippo signaling pathway_Homo sapiens_hsa043900.88164139
73Sphingolipid signaling pathway_Homo sapiens_hsa040710.88149457
74ErbB signaling pathway_Homo sapiens_hsa040120.87658289
75Proteoglycans in cancer_Homo sapiens_hsa052050.87000411
76Chemokine signaling pathway_Homo sapiens_hsa040620.86479195
77Parkinsons disease_Homo sapiens_hsa050120.85787810
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85563529
79Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.85551476
80Sulfur metabolism_Homo sapiens_hsa009200.84057581
81Prolactin signaling pathway_Homo sapiens_hsa049170.83719427
82Toll-like receptor signaling pathway_Homo sapiens_hsa046200.81183468
83PI3K-Akt signaling pathway_Homo sapiens_hsa041510.79899634
84FoxO signaling pathway_Homo sapiens_hsa040680.79834375
85TGF-beta signaling pathway_Homo sapiens_hsa043500.79268445
86Selenocompound metabolism_Homo sapiens_hsa004500.78955847
87Tight junction_Homo sapiens_hsa045300.77690383
88Central carbon metabolism in cancer_Homo sapiens_hsa052300.77473745
89Tuberculosis_Homo sapiens_hsa051520.76231821
90Mineral absorption_Homo sapiens_hsa049780.75615389
91Cell cycle_Homo sapiens_hsa041100.75377872
92Glioma_Homo sapiens_hsa052140.75088812
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.73752329
94Ras signaling pathway_Homo sapiens_hsa040140.73592183
95HIF-1 signaling pathway_Homo sapiens_hsa040660.72538875
96mTOR signaling pathway_Homo sapiens_hsa041500.72000122
97Pathways in cancer_Homo sapiens_hsa052000.71984811
98Arachidonic acid metabolism_Homo sapiens_hsa005900.71875193
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70132895
100MicroRNAs in cancer_Homo sapiens_hsa052060.69873054
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.69839001
102TNF signaling pathway_Homo sapiens_hsa046680.69828209
103Inositol phosphate metabolism_Homo sapiens_hsa005620.68597637
104Apoptosis_Homo sapiens_hsa042100.67993003
105Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.66974523
106Renin-angiotensin system_Homo sapiens_hsa046140.66812869
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66281991
108Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.65586640
109Choline metabolism in cancer_Homo sapiens_hsa052310.65558861
110Rap1 signaling pathway_Homo sapiens_hsa040150.64384627
111Insulin resistance_Homo sapiens_hsa049310.64125312
112Hepatitis C_Homo sapiens_hsa051600.63735726
113Endocytosis_Homo sapiens_hsa041440.63243118
114Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63069967
115Prostate cancer_Homo sapiens_hsa052150.62670395
116VEGF signaling pathway_Homo sapiens_hsa043700.62403296
117Steroid hormone biosynthesis_Homo sapiens_hsa001400.60417063
118Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.59583084
119Colorectal cancer_Homo sapiens_hsa052100.58363347
120Nucleotide excision repair_Homo sapiens_hsa034200.58026755
121Pancreatic cancer_Homo sapiens_hsa052120.57033630
122Herpes simplex infection_Homo sapiens_hsa051680.56281554
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56048499
124Serotonergic synapse_Homo sapiens_hsa047260.55821265
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54009725
126Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52991582
127HTLV-I infection_Homo sapiens_hsa051660.52763685
128Staphylococcus aureus infection_Homo sapiens_hsa051500.52318793
129Starch and sucrose metabolism_Homo sapiens_hsa005000.51476122
130RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.50080559
131Hepatitis B_Homo sapiens_hsa051610.49256237
132Epstein-Barr virus infection_Homo sapiens_hsa051690.49224394
133Dorso-ventral axis formation_Homo sapiens_hsa043200.48968142
134Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.47270920
135Huntingtons disease_Homo sapiens_hsa050160.46171056
136Legionellosis_Homo sapiens_hsa051340.45953520
137Influenza A_Homo sapiens_hsa051640.45306793
138Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44870140
139RNA polymerase_Homo sapiens_hsa030200.44783080
140ABC transporters_Homo sapiens_hsa020100.43570589
141Lysosome_Homo sapiens_hsa041420.43198654
142Galactose metabolism_Homo sapiens_hsa000520.41289536
143Phospholipase D signaling pathway_Homo sapiens_hsa040720.41231499

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