TMEM69

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1CENP-A containing nucleosome assembly (GO:0034080)5.25334119
2chromatin remodeling at centromere (GO:0031055)5.05384171
3regulation of nuclear cell cycle DNA replication (GO:0033262)5.02596072
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.00319460
5kinetochore assembly (GO:0051382)4.86758643
6DNA deamination (GO:0045006)4.81665032
7DNA replication checkpoint (GO:0000076)4.77173244
8telomere maintenance via semi-conservative replication (GO:0032201)4.75827992
9proteasome assembly (GO:0043248)4.62431882
10ribosome assembly (GO:0042255)4.61742812
11kinetochore organization (GO:0051383)4.58950177
12DNA strand elongation involved in DNA replication (GO:0006271)4.52200135
13rRNA modification (GO:0000154)4.47875234
14DNA strand elongation (GO:0022616)4.43965967
15chaperone-mediated protein transport (GO:0072321)4.34816651
16telomere maintenance via recombination (GO:0000722)4.32390803
17energy coupled proton transport, down electrochemical gradient (GO:0015985)4.22798891
18ATP synthesis coupled proton transport (GO:0015986)4.22798891
19DNA replication-independent nucleosome assembly (GO:0006336)4.20114326
20DNA replication-independent nucleosome organization (GO:0034724)4.20114326
21histone exchange (GO:0043486)4.14770383
22maturation of 5.8S rRNA (GO:0000460)4.14562141
23ribosomal large subunit biogenesis (GO:0042273)4.05654440
24telomere maintenance via telomere lengthening (GO:0010833)3.99452901
25ribosome biogenesis (GO:0042254)3.99037630
26purine nucleobase biosynthetic process (GO:0009113)3.97042299
27DNA replication initiation (GO:0006270)3.96924501
28nucleobase biosynthetic process (GO:0046112)3.91513084
29mitotic recombination (GO:0006312)3.90913761
30establishment of protein localization to mitochondrial membrane (GO:0090151)3.88292928
31ribonucleoprotein complex biogenesis (GO:0022613)3.86865038
32mitotic metaphase plate congression (GO:0007080)3.82334736
33viral transcription (GO:0019083)3.81335880
34mitochondrial DNA replication (GO:0006264)3.80251269
35maturation of SSU-rRNA (GO:0030490)3.80033880
36translational termination (GO:0006415)3.79121071
37establishment of integrated proviral latency (GO:0075713)3.78833380
38transcription elongation from RNA polymerase III promoter (GO:0006385)3.78014553
39termination of RNA polymerase III transcription (GO:0006386)3.78014553
40nucleotide-excision repair, DNA gap filling (GO:0006297)3.69443196
41mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.68941506
42deoxyribonucleotide biosynthetic process (GO:0009263)3.66931368
43transcription-coupled nucleotide-excision repair (GO:0006283)3.63971870
44DNA-dependent DNA replication (GO:0006261)3.63950265
45oxidative phosphorylation (GO:0006119)3.63325476
46SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.62758597
47negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.60668810
48IMP biosynthetic process (GO:0006188)3.57461679
49spliceosomal snRNP assembly (GO:0000387)3.57039908
50cotranslational protein targeting to membrane (GO:0006613)3.56865358
517-methylguanosine mRNA capping (GO:0006370)3.56006718
52regulation of mitochondrial translation (GO:0070129)3.54430332
53regulation of double-strand break repair via homologous recombination (GO:0010569)3.53851491
54RNA capping (GO:0036260)3.52688878
557-methylguanosine RNA capping (GO:0009452)3.52688878
56respiratory electron transport chain (GO:0022904)3.52583591
57negative regulation of DNA-dependent DNA replication (GO:2000104)3.52173227
58translational initiation (GO:0006413)3.51598489
59protein targeting to ER (GO:0045047)3.50930734
60DNA damage response, detection of DNA damage (GO:0042769)3.48017042
61ribosomal small subunit biogenesis (GO:0042274)3.47461470
62regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.47304537
63viral mRNA export from host cell nucleus (GO:0046784)3.47225121
64rRNA methylation (GO:0031167)3.46131491
65rRNA processing (GO:0006364)3.44514403
66electron transport chain (GO:0022900)3.43002451
67positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.42614604
68translation (GO:0006412)3.41414444
69pseudouridine synthesis (GO:0001522)3.41309816
70anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.41018196
71establishment of protein localization to endoplasmic reticulum (GO:0072599)3.39088275
72protein targeting to mitochondrion (GO:0006626)3.37148482
73rRNA metabolic process (GO:0016072)3.36560665
74termination of RNA polymerase I transcription (GO:0006363)3.36106799
75translational elongation (GO:0006414)3.35471804
76protein localization to endoplasmic reticulum (GO:0070972)3.34947084
77transcription from RNA polymerase I promoter (GO:0006360)3.34853724
78regulation of centriole replication (GO:0046599)3.34816931
79cullin deneddylation (GO:0010388)3.34169975
80protein localization to kinetochore (GO:0034501)3.33445598
81exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.33219622
82transcription from mitochondrial promoter (GO:0006390)3.33061744
83ribosomal small subunit assembly (GO:0000028)3.32830360
84positive regulation of ligase activity (GO:0051351)3.32637179
85establishment of viral latency (GO:0019043)3.31866338
86mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.30047986
87mitochondrial respiratory chain complex I assembly (GO:0032981)3.30047986
88NADH dehydrogenase complex assembly (GO:0010257)3.30047986
89protein complex biogenesis (GO:0070271)3.28853965
90intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.28512702
91signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.28512702
92mitochondrial respiratory chain complex assembly (GO:0033108)3.26868742
93respiratory chain complex IV assembly (GO:0008535)3.25853991
94transcription elongation from RNA polymerase I promoter (GO:0006362)3.24056485
95deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.23250299
96regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.22911976
97regulation of mitotic spindle checkpoint (GO:1903504)3.22911976
98negative regulation of ligase activity (GO:0051352)3.21918968
99negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.21918968
100spliceosomal complex assembly (GO:0000245)3.21758825
101DNA ligation (GO:0006266)3.21661204
102metaphase plate congression (GO:0051310)3.21395537
103nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.20809548
104cellular component biogenesis (GO:0044085)3.19989198
105protein deneddylation (GO:0000338)3.19987862
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.19981185
107negative regulation of sister chromatid segregation (GO:0033046)3.19981185
108negative regulation of mitotic sister chromatid separation (GO:2000816)3.19981185
109negative regulation of mitotic sister chromatid segregation (GO:0033048)3.19981185
110nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.18750132
111protein-cofactor linkage (GO:0018065)3.17856954
112DNA double-strand break processing (GO:0000729)3.17343966
113regulation of ubiquitin-protein transferase activity (GO:0051438)3.16628159
114signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.12812002
115signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.12812002
116signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.12812002
117DNA catabolic process, exonucleolytic (GO:0000738)3.12737158
118negative regulation of chromosome segregation (GO:0051985)3.11998584
119regulation of cellular amino acid metabolic process (GO:0006521)3.10755907
120negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.09391870
121deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.09096237
122formation of translation preinitiation complex (GO:0001731)3.09057588
123pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.08801973
124histone mRNA metabolic process (GO:0008334)3.08767665
125signal transduction involved in DNA integrity checkpoint (GO:0072401)3.07616261
126signal transduction involved in DNA damage checkpoint (GO:0072422)3.07616261
127signal transduction involved in cell cycle checkpoint (GO:0072395)3.05465961
128regulation of ligase activity (GO:0051340)3.05380771
129spindle checkpoint (GO:0031577)3.04802031
130establishment of protein localization to mitochondrion (GO:0072655)3.04648713
131RNA-dependent DNA replication (GO:0006278)3.03954390
132deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.03682069
133tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.02693115
134RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.02693115
135DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.01742973
136regulation of helicase activity (GO:0051095)3.01736127
137DNA replication (GO:0006260)2.99891983
138regulation of centrosome cycle (GO:0046605)2.99360746
139telomere organization (GO:0032200)2.98840271
140positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.98167179
141telomere maintenance (GO:0000723)2.97945014
142spindle assembly checkpoint (GO:0071173)2.97911724

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.22342182
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.46629844
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.39906936
4* EST1_17652178_ChIP-ChIP_JURKAT_Human3.78147982
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.70391498
6* GABP_17652178_ChIP-ChIP_JURKAT_Human3.67573953
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.54017513
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.31088146
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.04738829
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.04043652
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97155675
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.94935982
13* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.93181561
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.91069161
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.87566964
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.86550096
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.83034445
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79275933
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.69286063
20* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.56366863
21* VDR_23849224_ChIP-Seq_CD4+_Human2.46140800
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.43233630
23* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.42217516
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.41187421
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.36757357
26XRN2_22483619_ChIP-Seq_HELA_Human2.25196571
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.22227994
28* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.20149458
29* FOXP3_21729870_ChIP-Seq_TREG_Human2.18773887
30DCP1A_22483619_ChIP-Seq_HELA_Human2.11962247
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.10584355
32YY1_21170310_ChIP-Seq_MESCs_Mouse2.05839323
33* ELK1_19687146_ChIP-ChIP_HELA_Human2.02995565
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99432046
35TTF2_22483619_ChIP-Seq_HELA_Human1.98833462
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.97242287
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.96461461
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.93669230
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.85146638
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.82469835
41MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80593034
42* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.74302877
43* GABP_19822575_ChIP-Seq_HepG2_Human1.69834987
44AR_21909140_ChIP-Seq_LNCAP_Human1.69074619
45KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.63275729
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58056441
47POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57722911
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.56668243
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53408942
50NOTCH1_21737748_ChIP-Seq_TLL_Human1.50613381
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.48458730
52* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.46599295
53* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46123903
54SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.44129924
55TP63_19390658_ChIP-ChIP_HaCaT_Human1.35331484
56CIITA_25753668_ChIP-Seq_RAJI_Human1.34164071
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.33475823
58ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.31336197
59HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.30620477
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24452193
61ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24353968
62KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.19961968
63* KDM5A_27292631_Chip-Seq_BREAST_Human1.18939852
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.16489718
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15638840
66MYC_18940864_ChIP-ChIP_HL60_Human1.14305841
67KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.13076396
68KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.13076396
69KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.13076396
70SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.12067812
71* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.10309281
72SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10076843
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09941472
74ELK1_22589737_ChIP-Seq_MCF10A_Human1.09674801
75EWS_26573619_Chip-Seq_HEK293_Human1.08900334
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06633869
77PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.03774666
78NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02175642
79POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01427135
80ZNF274_21170338_ChIP-Seq_K562_Hela0.99720694
81ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97003337
82STAT3_1855785_ChIP-Seq_MESCs_Mouse0.95102251
83CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.94520196
84E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93969170
85SOX2_16153702_ChIP-ChIP_HESCs_Human0.91573310
86CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.91160942
87RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88483677
88* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.88434831
89FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.88163833
90NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.85787436
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85771031
92SOX17_20123909_ChIP-Seq_XEN_Mouse0.85212036
93CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83462709
94TCF3_18692474_ChIP-Seq_MEFs_Mouse0.83015519
95TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.80953559
96KAP1_22055183_ChIP-Seq_ESCs_Mouse0.80129010
97FUS_26573619_Chip-Seq_HEK293_Human0.78548412
98GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.78390722
99NANOG_16153702_ChIP-ChIP_HESCs_Human0.78388009
100ELF5_23300383_ChIP-Seq_T47D_Human0.76957306
101SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.76171434
102POU5F1_16153702_ChIP-ChIP_HESCs_Human0.76058854
103FLI1_27457419_Chip-Seq_LIVER_Mouse0.76008917
104NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.75948950
105VDR_22108803_ChIP-Seq_LS180_Human0.75861094
106* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.75304946
107SALL1_21062744_ChIP-ChIP_HESCs_Human0.71871786
108CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.71046240
109ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.71040538
110TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71031396
111IRF1_19129219_ChIP-ChIP_H3396_Human0.70489136
112SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.70110986
113SOX2_18692474_ChIP-Seq_MEFs_Mouse0.70090189
114KLF4_18555785_ChIP-Seq_MESCs_Mouse0.70071267
115TFEB_21752829_ChIP-Seq_HELA_Human0.69912104
116* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66241541
117DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.65982324
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.64099307
119SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.63893685

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.18442187
2MP0003111_abnormal_nucleus_morphology4.72627714
3MP0010094_abnormal_chromosome_stability4.36263992
4MP0008057_abnormal_DNA_replication4.33844219
5MP0008058_abnormal_DNA_repair4.11340063
6MP0003077_abnormal_cell_cycle3.79740452
7MP0004957_abnormal_blastocyst_morpholog3.72512097
8MP0008007_abnormal_cellular_replicative3.06989740
9MP0003718_maternal_effect2.99515008
10MP0008932_abnormal_embryonic_tissue2.90158547
11MP0008877_abnormal_DNA_methylation2.79759238
12MP0001188_hyperpigmentation2.64306263
13MP0003806_abnormal_nucleotide_metabolis2.57486899
14MP0003786_premature_aging2.51175155
15MP0003941_abnormal_skin_development2.31767256
16MP0006292_abnormal_olfactory_placode2.25701336
17MP0000566_synostosis2.12735751
18MP0002160_abnormal_reproductive_system2.06373336
19MP0004133_heterotaxia1.90282684
20MP0003890_abnormal_embryonic-extraembry1.86325553
21MP0000372_irregular_coat_pigmentation1.84925970
22MP0009379_abnormal_foot_pigmentation1.82329408
23MP0005389_reproductive_system_phenotype1.78435187
24MP0003186_abnormal_redox_activity1.63877419
25MP0002938_white_spotting1.63363902
26MP0002210_abnormal_sex_determination1.62535482
27MP0003136_yellow_coat_color1.60487889
28MP0001986_abnormal_taste_sensitivity1.54299746
29MP0000350_abnormal_cell_proliferation1.53825881
30MP0001529_abnormal_vocalization1.51408645
31MP0003315_abnormal_perineum_morphology1.51321576
32MP0001853_heart_inflammation1.45336248
33MP0004381_abnormal_hair_follicle1.44367505
34MP0001730_embryonic_growth_arrest1.43028428
35MP0002277_abnormal_respiratory_mucosa1.40903830
36MP0001919_abnormal_reproductive_system1.40445594
37MP0005075_abnormal_melanosome_morpholog1.38421077
38MP0006072_abnormal_retinal_apoptosis1.37416247
39MP0009697_abnormal_copulation1.36768556
40MP0001145_abnormal_male_reproductive1.35494516
41MP0002837_dystrophic_cardiac_calcinosis1.32462927
42MP0000313_abnormal_cell_death1.30836622
43MP0002234_abnormal_pharynx_morphology1.28292027
44MP0000653_abnormal_sex_gland1.20277719
45MP0001929_abnormal_gametogenesis1.18820737
46MP0002163_abnormal_gland_morphology1.18048197
47MP0001672_abnormal_embryogenesis/_devel1.13252359
48MP0005380_embryogenesis_phenotype1.13252359
49MP0001119_abnormal_female_reproductive1.12716540
50MP0005409_darkened_coat_color1.12231687
51MP0002019_abnormal_tumor_incidence1.08184874
52MP0001697_abnormal_embryo_size1.07697466
53MP0003123_paternal_imprinting1.06706092
54MP0003121_genomic_imprinting1.04179764
55MP0005084_abnormal_gallbladder_morpholo1.03985158
56MP0005394_taste/olfaction_phenotype1.03616104
57MP0005499_abnormal_olfactory_system1.03616104
58MP0005408_hypopigmentation1.01548105
59MP0001764_abnormal_homeostasis0.98608290
60MP0005410_abnormal_fertilization0.98375632
61MP0006035_abnormal_mitochondrial_morpho0.95991415
62MP0003119_abnormal_digestive_system0.94379408
63MP0002085_abnormal_embryonic_tissue0.94312059
64MP0010307_abnormal_tumor_latency0.94274405
65MP0001293_anophthalmia0.94036775
66MP0002080_prenatal_lethality0.93705754
67MP0002396_abnormal_hematopoietic_system0.93356705
68MP0002132_abnormal_respiratory_system0.91850016
69MP0001286_abnormal_eye_development0.90541772
70MP0006036_abnormal_mitochondrial_physio0.90395506
71MP0008995_early_reproductive_senescence0.89967672
72MP0005395_other_phenotype0.89930380
73MP0002751_abnormal_autonomic_nervous0.89926996
74MP0000858_altered_metastatic_potential0.89593920
75MP0000490_abnormal_crypts_of0.87983033
76MP0010352_gastrointestinal_tract_polyps0.87935006
77MP0003984_embryonic_growth_retardation0.87800081
78MP0005332_abnormal_amino_acid0.85426814
79MP0002088_abnormal_embryonic_growth/wei0.84216937
80MP0001186_pigmentation_phenotype0.82705747
81MP0005670_abnormal_white_adipose0.82519097
82MP0005379_endocrine/exocrine_gland_phen0.81843776
83MP0003763_abnormal_thymus_physiology0.80410552
84MP0008789_abnormal_olfactory_epithelium0.78816306
85MP0000631_abnormal_neuroendocrine_gland0.76689790
86MP0002161_abnormal_fertility/fecundity0.76516197
87MP0000015_abnormal_ear_pigmentation0.76351135
88MP0002102_abnormal_ear_morphology0.75866806
89MP0002638_abnormal_pupillary_reflex0.75580180
90MP0002111_abnormal_tail_morphology0.75258229
91MP0004147_increased_porphyrin_level0.74451604
92MP0005266_abnormal_metabolism0.74225926
93MP0003936_abnormal_reproductive_system0.73910659
94MP0000689_abnormal_spleen_morphology0.73726319
95MP0004197_abnormal_fetal_growth/weight/0.73075403
96MP0000358_abnormal_cell_content/0.72479692
97MP0002090_abnormal_vision0.72265740
98MP0010030_abnormal_orbit_morphology0.71336039
99MP0003567_abnormal_fetal_cardiomyocyte0.71270988
100MP0003698_abnormal_male_reproductive0.70331472
101MP0003937_abnormal_limbs/digits/tail_de0.69318702
102MP0000703_abnormal_thymus_morphology0.68451501
103MP0003699_abnormal_female_reproductive0.67897818
104MP0001661_extended_life_span0.67708298
105MP0002138_abnormal_hepatobiliary_system0.67182164
106MP0002075_abnormal_coat/hair_pigmentati0.66871280
107MP0003646_muscle_fatigue0.66676608
108MP0005253_abnormal_eye_physiology0.65614290
109MP0009333_abnormal_splenocyte_physiolog0.65373607
110MP0002095_abnormal_skin_pigmentation0.65276117
111MP0004215_abnormal_myocardial_fiber0.65130140
112MP0000613_abnormal_salivary_gland0.64543222
113MP0001542_abnormal_bone_strength0.64207348
114MP0005501_abnormal_skin_physiology0.64168142
115MP0009672_abnormal_birth_weight0.64035178
116MP0002876_abnormal_thyroid_physiology0.63717511
117MP0003938_abnormal_ear_development0.63073651
118MP0002086_abnormal_extraembryonic_tissu0.62727058
119MP0000049_abnormal_middle_ear0.61840509
120MP0005636_abnormal_mineral_homeostasis0.61617183
121MP0005384_cellular_phenotype0.61524461
122MP0002722_abnormal_immune_system0.61049966
123MP0000647_abnormal_sebaceous_gland0.60769836
124MP0005171_absent_coat_pigmentation0.60672405
125MP0003195_calcinosis0.59666213
126MP0001881_abnormal_mammary_gland0.57974105
127MP0003950_abnormal_plasma_membrane0.57780114
128MP0002233_abnormal_nose_morphology0.57382443
129MP0005174_abnormal_tail_pigmentation0.56905926
130MP0004019_abnormal_vitamin_homeostasis0.55386336
131MP0004142_abnormal_muscle_tone0.55142573
132MP0005551_abnormal_eye_electrophysiolog0.54089030
133MP0000678_abnormal_parathyroid_gland0.53321056
134MP0002084_abnormal_developmental_patter0.51925296

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.55709153
2Progressive external ophthalmoplegia (HP:0000590)4.74981825
3Breast hypoplasia (HP:0003187)4.58185433
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.56417353
5Chromsome breakage (HP:0040012)4.42400343
6Abnormal mitochondria in muscle tissue (HP:0008316)4.19616746
7Acute encephalopathy (HP:0006846)4.18156750
8Hepatic necrosis (HP:0002605)3.85227111
9Hepatocellular necrosis (HP:0001404)3.85098738
10Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.81827754
11Progressive macrocephaly (HP:0004481)3.73075973
12Lipid accumulation in hepatocytes (HP:0006561)3.68510264
13Duplicated collecting system (HP:0000081)3.52878318
14Oral leukoplakia (HP:0002745)3.43082813
15Rough bone trabeculation (HP:0100670)3.39348186
16Reticulocytopenia (HP:0001896)3.29272377
17Meckel diverticulum (HP:0002245)3.28386061
18Carpal bone hypoplasia (HP:0001498)3.25733823
19Abnormality of the renal collecting system (HP:0004742)3.25014286
20Cerebral edema (HP:0002181)3.24934671
21Abnormality of chromosome stability (HP:0003220)3.23476906
22Cerebral hypomyelination (HP:0006808)3.21085881
23Abnormality of the preputium (HP:0100587)3.12468299
24Aplastic anemia (HP:0001915)3.09824414
25Absent radius (HP:0003974)3.09144876
26Increased serum pyruvate (HP:0003542)3.08934152
27Patellar aplasia (HP:0006443)3.04837160
28Abnormality of the ileum (HP:0001549)3.00605770
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.99772951
30Lactic acidosis (HP:0003128)2.91080637
31Absent forearm bone (HP:0003953)2.90391488
32Aplasia involving forearm bones (HP:0009822)2.90391488
33Aplasia/Hypoplasia of the patella (HP:0006498)2.88213668
34Macrocytic anemia (HP:0001972)2.86165625
35Microvesicular hepatic steatosis (HP:0001414)2.83021770
36Abnormality of glycolysis (HP:0004366)2.82328934
37Aplasia/Hypoplasia of the uvula (HP:0010293)2.80211077
38Methylmalonic acidemia (HP:0002912)2.74730017
39Increased intramyocellular lipid droplets (HP:0012240)2.74158005
40Colon cancer (HP:0003003)2.72581585
41Bone marrow hypocellularity (HP:0005528)2.70339283
42Premature graying of hair (HP:0002216)2.70313016
43External ophthalmoplegia (HP:0000544)2.67872644
44Absent thumb (HP:0009777)2.66426151
45Proximal tubulopathy (HP:0000114)2.63715057
46Abnormal trabecular bone morphology (HP:0100671)2.60512012
47Hyperglycinemia (HP:0002154)2.60424350
48Aplasia/Hypoplasia of the sacrum (HP:0008517)2.59959895
49Type 2 muscle fiber atrophy (HP:0003554)2.58371022
50Generalized aminoaciduria (HP:0002909)2.56470931
51Abnormality of methionine metabolism (HP:0010901)2.55749341
52Aplasia/Hypoplasia involving the musculature (HP:0001460)2.53713550
53Granulocytopenia (HP:0001913)2.52446373
54Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.50498194
55Abnormal protein N-linked glycosylation (HP:0012347)2.50498194
56Abnormal protein glycosylation (HP:0012346)2.50498194
57Abnormal glycosylation (HP:0012345)2.50498194
58Respiratory failure (HP:0002878)2.50431191
59Impulsivity (HP:0100710)2.49953567
60Increased serum lactate (HP:0002151)2.48801553
61Aplasia/Hypoplasia of the earlobes (HP:0009906)2.47961725
62Respiratory difficulties (HP:0002880)2.46006340
63Megaloblastic anemia (HP:0001889)2.44472128
64Abnormal spermatogenesis (HP:0008669)2.44400021
65Type I transferrin isoform profile (HP:0003642)2.43539634
66Muscle fiber atrophy (HP:0100295)2.42723991
67Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.40699210
68Neoplasm of the pancreas (HP:0002894)2.38639830
69Horseshoe kidney (HP:0000085)2.38486588
70Pancytopenia (HP:0001876)2.35381438
71Triphalangeal thumb (HP:0001199)2.35032086
72Cellular immunodeficiency (HP:0005374)2.34286531
73Duodenal stenosis (HP:0100867)2.33971886
74Small intestinal stenosis (HP:0012848)2.33971886
75Progressive muscle weakness (HP:0003323)2.30618086
76Increased muscle lipid content (HP:0009058)2.28926460
77Abnormality of serum amino acid levels (HP:0003112)2.28882496
78Methylmalonic aciduria (HP:0012120)2.24546198
79Abnormality of aspartate family amino acid metabolism (HP:0010899)2.21820430
80Lethargy (HP:0001254)2.21816180
81Abnormality of cells of the erythroid lineage (HP:0012130)2.20871010
82Abnormality of pyrimidine metabolism (HP:0004353)2.18500021
83Reduced antithrombin III activity (HP:0001976)2.15601030
84Hypoglycemic coma (HP:0001325)2.15457777
85Exercise intolerance (HP:0003546)2.14974919
86Multiple enchondromatosis (HP:0005701)2.11930841
87Abnormal number of erythroid precursors (HP:0012131)2.11198584
88Abnormality of alanine metabolism (HP:0010916)2.09166517
89Hyperalaninemia (HP:0003348)2.09166517
90Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09166517
91Leukodystrophy (HP:0002415)2.08647343
92Clubbing of toes (HP:0100760)2.07569972
93Increased hepatocellular lipid droplets (HP:0006565)2.07303669
94Pancreatic cysts (HP:0001737)2.07166320
95Sloping forehead (HP:0000340)2.07007711
96Hypoplasia of the pons (HP:0012110)2.06433681
97Acute necrotizing encephalopathy (HP:0006965)2.01155659
98Abnormality of the pons (HP:0007361)2.01043277
99Myelodysplasia (HP:0002863)1.99650088
100Increased CSF lactate (HP:0002490)1.99022184
101Pallor (HP:0000980)1.98825730
102Supernumerary spleens (HP:0009799)1.98736294
103Abnormality of the labia minora (HP:0012880)1.97930753
104CNS demyelination (HP:0007305)1.97912194
105Testicular atrophy (HP:0000029)1.97572632
1063-Methylglutaconic aciduria (HP:0003535)1.97073059
107Abnormality of the duodenum (HP:0002246)1.95742204
108Ectopic kidney (HP:0000086)1.95577858
109Poor head control (HP:0002421)1.95486063
110Decreased activity of mitochondrial respiratory chain (HP:0008972)1.95431570
111Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.95431570
112Abnormality of urine glucose concentration (HP:0011016)1.95203693
113Glycosuria (HP:0003076)1.95203693
114Abnormal lung lobation (HP:0002101)1.94892210
115Medulloblastoma (HP:0002885)1.94586872
116Exertional dyspnea (HP:0002875)1.91831184
117Optic disc pallor (HP:0000543)1.90688990
118Degeneration of anterior horn cells (HP:0002398)1.90078448
119Abnormality of the anterior horn cell (HP:0006802)1.90078448
120Mitochondrial inheritance (HP:0001427)1.89926111
121Sparse eyelashes (HP:0000653)1.89554638
122Neoplasm of the colon (HP:0100273)1.89462936
123Cleft eyelid (HP:0000625)1.89392696
124Microretrognathia (HP:0000308)1.88628951
125Abnormality of glycine metabolism (HP:0010895)1.86390471
126Abnormality of serine family amino acid metabolism (HP:0010894)1.86390471
127Prolonged neonatal jaundice (HP:0006579)1.85989137
128Hyperglycinuria (HP:0003108)1.84199166
129Renal Fanconi syndrome (HP:0001994)1.82711168
130Long foot (HP:0001833)1.82552958
131Median cleft lip (HP:0000161)1.81033282
132Osteomalacia (HP:0002749)1.80552400
133Short thumb (HP:0009778)1.80083949
134Agnosia (HP:0010524)1.79948112
135Nephroblastoma (Wilms tumor) (HP:0002667)1.79678840
136Abnormality of DNA repair (HP:0003254)1.78568134
137Hypoplasia of the radius (HP:0002984)1.78140115
138Aplasia/hypoplasia of the uterus (HP:0008684)1.76959852
139Azoospermia (HP:0000027)1.76858576
140CNS hypomyelination (HP:0003429)1.76568458
141Ureteral duplication (HP:0000073)1.76104872
142Tracheoesophageal fistula (HP:0002575)1.75890005
143Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.75560348
144Abnormality of sulfur amino acid metabolism (HP:0004339)1.75177162
145Fibular aplasia (HP:0002990)1.73693739
146Premature ovarian failure (HP:0008209)1.73687715
147Trismus (HP:0000211)1.73369910
148Nausea (HP:0002018)1.72472969
149Dicarboxylic aciduria (HP:0003215)1.72347130
150Abnormality of dicarboxylic acid metabolism (HP:0010995)1.72347130
151Squamous cell carcinoma (HP:0002860)1.70897379
152IgM deficiency (HP:0002850)1.70769243

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK35.10240502
2PLK44.97136889
3BUB14.13133214
4EIF2AK13.94024559
5VRK23.60388536
6ZAK3.42195776
7SRPK13.12290329
8STK163.10871429
9PBK2.99244079
10IRAK42.66968328
11WEE12.63138635
12CDC72.42767590
13EIF2AK32.41704811
14PDK22.19857739
15TTK2.04197180
16IRAK21.97133015
17TESK21.97034590
18IRAK11.95384294
19MKNK11.87449147
20CDK191.81990341
21MKNK21.79702721
22MARK11.76798486
23TLK11.67714965
24PLK11.54976212
25VRK11.47549486
26ACVR1B1.47349206
27TRIM281.46558401
28WNK31.42575747
29EPHA21.42300609
30TSSK61.39334383
31PLK31.34574882
32MAP4K21.32214091
33STK38L1.29788125
34ATR1.27745434
35AKT31.17894963
36EIF2AK21.15787959
37RPS6KB21.10273360
38NME21.04136002
39DYRK31.03037414
40AURKB1.00168992
41CHEK20.98758262
42AURKA0.94837029
43CDK70.94771126
44BRSK20.94641314
45PRPF4B0.93126454
46STK40.89283962
47TAF10.84138022
48CSNK1G30.81441862
49BRD40.81119956
50CASK0.78742227
51GRK10.77235233
52CSNK1G10.76567448
53BRSK10.76211510
54MAP3K120.75328348
55MARK30.73648370
56NEK10.72151111
57NEK60.71529790
58NME10.70756753
59CHEK10.70446731
60NLK0.70289545
61DYRK20.68744899
62ATM0.68393951
63TGFBR10.68238225
64BLK0.66527438
65STK100.66244795
66PRKCI0.61704228
67DAPK10.61472539
68YES10.60535803
69CSNK1A1L0.59135498
70BCKDK0.58307703
71RPS6KA50.57915496
72CSNK2A10.56559859
73NEK20.53787705
74PAK40.53341047
75PLK20.52504898
76PNCK0.50429961
77MAPKAPK30.50057247
78CCNB10.49777900
79STK30.48641100
80PASK0.48520853
81TIE10.48312539
82CSNK2A20.48036940
83ERBB30.46978823
84CDK80.46759077
85CSNK1G20.46389653
86KDR0.46318540
87TAOK20.46311721
88MAP3K80.44217097
89BRAF0.43639932
90CDK10.41560748
91CDK20.40890909
92FLT30.40860309
93PIM20.40515190
94TESK10.39605428
95RPS6KA40.38665464
96MAPK70.38496568
97ABL20.38300913
98MAP3K110.38058867
99BCR0.37655618
100PINK10.37094118
101TEC0.35818449
102WNK40.35126645
103BMPR1B0.35044331
104CDC42BPA0.34032505
105CLK10.33913188
106CDK90.33093277
107STK240.32700681
108SCYL20.32609412
109ADRBK20.31910341
110TAOK30.31298677
111LIMK10.29933691
112ALK0.29618351
113NUAK10.29519657
114PAK10.29331145
115MST40.29130815
116ERBB40.28964723
117IKBKB0.28329120
118TNIK0.27481621
119MELK0.26069677
120MAP2K70.25930699
121PRKDC0.25460476
122CDK40.25389772
123OBSCN0.25313315
124NEK90.24926815
125PIM10.24585151
126ARAF0.23564732
127TXK0.23344648
128OXSR10.22931220
129AKT20.21582039
130CDK30.18708936
131CSNK1E0.17472677

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.55639407
2Mismatch repair_Homo sapiens_hsa034304.08657156
3Proteasome_Homo sapiens_hsa030504.02590323
4RNA polymerase_Homo sapiens_hsa030203.79361648
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.63981301
6Ribosome_Homo sapiens_hsa030103.43691575
7Spliceosome_Homo sapiens_hsa030403.08553739
8One carbon pool by folate_Homo sapiens_hsa006702.93306823
9Fanconi anemia pathway_Homo sapiens_hsa034602.89918027
10Homologous recombination_Homo sapiens_hsa034402.88947523
11Pyrimidine metabolism_Homo sapiens_hsa002402.71066944
12Nucleotide excision repair_Homo sapiens_hsa034202.69390305
13RNA transport_Homo sapiens_hsa030132.51795976
14Base excision repair_Homo sapiens_hsa034102.36029208
15Non-homologous end-joining_Homo sapiens_hsa034502.34285687
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16618876
17Cell cycle_Homo sapiens_hsa041102.16048189
18Basal transcription factors_Homo sapiens_hsa030221.93284343
19RNA degradation_Homo sapiens_hsa030181.79990933
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64339033
21Purine metabolism_Homo sapiens_hsa002301.59004426
22Propanoate metabolism_Homo sapiens_hsa006401.56262292
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.48430681
24Protein export_Homo sapiens_hsa030601.44080334
25p53 signaling pathway_Homo sapiens_hsa041151.42913577
26Oxidative phosphorylation_Homo sapiens_hsa001901.36906961
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.25283922
28Parkinsons disease_Homo sapiens_hsa050121.24093028
29Huntingtons disease_Homo sapiens_hsa050161.23552671
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.21692435
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.16012109
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15026241
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.14864377
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.14455860
35Epstein-Barr virus infection_Homo sapiens_hsa051691.14199026
36Folate biosynthesis_Homo sapiens_hsa007901.10992354
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.10139388
38mRNA surveillance pathway_Homo sapiens_hsa030151.06741463
39Cyanoamino acid metabolism_Homo sapiens_hsa004600.99930232
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94590084
41Glutathione metabolism_Homo sapiens_hsa004800.92516828
42Drug metabolism - other enzymes_Homo sapiens_hsa009830.91421177
43Vitamin B6 metabolism_Homo sapiens_hsa007500.82999976
44Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.82795221
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.82085951
46Selenocompound metabolism_Homo sapiens_hsa004500.82067037
47Cardiac muscle contraction_Homo sapiens_hsa042600.81617922
48Systemic lupus erythematosus_Homo sapiens_hsa053220.78293260
49Sulfur metabolism_Homo sapiens_hsa009200.74369903
50Arachidonic acid metabolism_Homo sapiens_hsa005900.70547361
51Biosynthesis of amino acids_Homo sapiens_hsa012300.69995864
52Sulfur relay system_Homo sapiens_hsa041220.69800583
53Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65191399
54Pentose phosphate pathway_Homo sapiens_hsa000300.64647915
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63990019
56Butanoate metabolism_Homo sapiens_hsa006500.61733419
57Alzheimers disease_Homo sapiens_hsa050100.61410921
58Metabolic pathways_Homo sapiens_hsa011000.60296074
59Herpes simplex infection_Homo sapiens_hsa051680.57230136
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.56997371
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.55911352
62Fatty acid metabolism_Homo sapiens_hsa012120.55822089
63N-Glycan biosynthesis_Homo sapiens_hsa005100.55240242
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54865694
65Peroxisome_Homo sapiens_hsa041460.48995017
66Arginine and proline metabolism_Homo sapiens_hsa003300.46794875
67Retinol metabolism_Homo sapiens_hsa008300.46769475
68Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.44734951
69Phenylalanine metabolism_Homo sapiens_hsa003600.44083787
70NF-kappa B signaling pathway_Homo sapiens_hsa040640.42700937
71Linoleic acid metabolism_Homo sapiens_hsa005910.41316774
72Tyrosine metabolism_Homo sapiens_hsa003500.40038911
73Sphingolipid metabolism_Homo sapiens_hsa006000.38200902
74beta-Alanine metabolism_Homo sapiens_hsa004100.37697556
75Oocyte meiosis_Homo sapiens_hsa041140.37612456
76Carbon metabolism_Homo sapiens_hsa012000.36064862
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35967355
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35802089
79Collecting duct acid secretion_Homo sapiens_hsa049660.33876939
80Viral carcinogenesis_Homo sapiens_hsa052030.33519640
81Other glycan degradation_Homo sapiens_hsa005110.32234496
82Maturity onset diabetes of the young_Homo sapiens_hsa049500.29384706
83Fatty acid degradation_Homo sapiens_hsa000710.29195733
84Phototransduction_Homo sapiens_hsa047440.28145912
85Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28093299
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27923333
87HTLV-I infection_Homo sapiens_hsa051660.27895623
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26957784
89Fructose and mannose metabolism_Homo sapiens_hsa000510.26821985
90Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26652052
91Steroid hormone biosynthesis_Homo sapiens_hsa001400.26246788
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.26032861
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.25404028
94Caffeine metabolism_Homo sapiens_hsa002320.25160976
95Vitamin digestion and absorption_Homo sapiens_hsa049770.24085424
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.22909364
97Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21692525
98Measles_Homo sapiens_hsa051620.21004182
99Galactose metabolism_Homo sapiens_hsa000520.20919331
100Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20620252
101Chemical carcinogenesis_Homo sapiens_hsa052040.18733454
102Regulation of autophagy_Homo sapiens_hsa041400.18473165
103Autoimmune thyroid disease_Homo sapiens_hsa053200.16731903
104Histidine metabolism_Homo sapiens_hsa003400.14699523
105Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.14527536
106Allograft rejection_Homo sapiens_hsa053300.14322018
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14290055
108Intestinal immune network for IgA production_Homo sapiens_hsa046720.11138280
109Primary immunodeficiency_Homo sapiens_hsa053400.09711578
110Asthma_Homo sapiens_hsa053100.08055542
111Graft-versus-host disease_Homo sapiens_hsa053320.07979164
1122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.07791512
113Hematopoietic cell lineage_Homo sapiens_hsa046400.07750883
114Steroid biosynthesis_Homo sapiens_hsa001000.07057338
115Fatty acid elongation_Homo sapiens_hsa000620.06278584
116Renin-angiotensin system_Homo sapiens_hsa046140.05724660
117Pyruvate metabolism_Homo sapiens_hsa006200.05250203
118Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.05041403
119Tryptophan metabolism_Homo sapiens_hsa003800.04761228
120Olfactory transduction_Homo sapiens_hsa047400.04716141
121Alcoholism_Homo sapiens_hsa050340.04633106

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