TMEM244

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H4-K5 acetylation (GO:0043981)8.69575770
2histone H4-K8 acetylation (GO:0043982)8.69575770
3negative regulation of stress fiber assembly (GO:0051497)8.52860388
4negative regulation of protein localization to plasma membrane (GO:1903077)8.43643837
5DNA deamination (GO:0045006)7.57526703
6negative regulation of actin filament bundle assembly (GO:0032232)7.05183367
7histone H4-K16 acetylation (GO:0043984)6.78868490
8negative regulation of establishment of protein localization to plasma membrane (GO:0090005)6.75878957
9retinal rod cell development (GO:0046548)6.71347884
10negative regulation by host of viral transcription (GO:0043922)6.61450347
11regulation of relaxation of muscle (GO:1901077)6.45517636
12regulation of lymphocyte chemotaxis (GO:1901623)5.87030478
13purine nucleoside bisphosphate biosynthetic process (GO:0034033)5.81699935
14ribonucleoside bisphosphate biosynthetic process (GO:0034030)5.81699935
15nucleoside bisphosphate biosynthetic process (GO:0033866)5.81699935
163-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)5.79500963
17purine ribonucleoside bisphosphate metabolic process (GO:0034035)5.79500963
18regulation of cell communication by electrical coupling (GO:0010649)5.62656640
19negative regulation of T cell mediated immunity (GO:0002710)5.58340868
20regulation of protein polyubiquitination (GO:1902914)5.48239876
21lateral ventricle development (GO:0021670)5.40369806
22regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.39629321
23cAMP-mediated signaling (GO:0019933)5.33154500
24maturation of 5.8S rRNA (GO:0000460)5.18917290
25mitotic sister chromatid cohesion (GO:0007064)4.95421403
26retinal cone cell development (GO:0046549)4.94333799
27peptidyl-histidine modification (GO:0018202)4.92259301
28GDP-mannose metabolic process (GO:0019673)4.92112147
29cellular response to epinephrine stimulus (GO:0071872)4.82045038
30rRNA transcription (GO:0009303)4.81598238
31parturition (GO:0007567)4.80106860
32regulation of cardiac muscle cell contraction (GO:0086004)4.55423889
33negative regulation of gene silencing (GO:0060969)4.52098229
34positive regulation of calcium-mediated signaling (GO:0050850)4.46143579
35iron ion import (GO:0097286)4.45306340
36glycerophospholipid catabolic process (GO:0046475)4.28442757
37adrenergic receptor signaling pathway (GO:0071875)4.25585401
38regulation of protein localization to plasma membrane (GO:1903076)4.20062852
39regulation of transcription from RNA polymerase I promoter (GO:0006356)4.17431896
40regulation of chronic inflammatory response (GO:0002676)4.13615547
41viral mRNA export from host cell nucleus (GO:0046784)4.11996110
42positive regulation of gene expression, epigenetic (GO:0045815)4.01919804
43cytidine deamination (GO:0009972)4.01509933
44cytidine metabolic process (GO:0046087)4.01509933
45cytidine catabolic process (GO:0006216)4.01509933
46negative regulation of interleukin-2 production (GO:0032703)4.00985868
47response to epinephrine (GO:0071871)3.98021003
48negative regulation of DNA repair (GO:0045738)3.88402840
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.84218966
50negative regulation of cell killing (GO:0031342)3.84218966
51positive regulation of gastrulation (GO:2000543)3.83119759
52regulation of B cell differentiation (GO:0045577)3.82014390
53regulation of interleukin-5 production (GO:0032674)3.73386793
54cyclic-nucleotide-mediated signaling (GO:0019935)3.73040053
55positive regulation of lymphocyte migration (GO:2000403)3.69131202
56positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.69079622
57negative regulation of viral transcription (GO:0032897)3.68322707
58inner mitochondrial membrane organization (GO:0007007)3.66804453
59somatic stem cell division (GO:0048103)3.62851341
60phosphatidylinositol acyl-chain remodeling (GO:0036149)3.58884032
61cAMP catabolic process (GO:0006198)3.56249214
62antigen processing and presentation via MHC class Ib (GO:0002475)3.55052130
63regulation of viral entry into host cell (GO:0046596)3.52263095
64folic acid-containing compound biosynthetic process (GO:0009396)3.51732562
65regulation of T cell mediated cytotoxicity (GO:0001914)3.49235062
66regulation of actin filament-based movement (GO:1903115)3.48428025
67negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.47555024
68negative regulation of heart contraction (GO:0045822)3.44144617
69CDP-diacylglycerol biosynthetic process (GO:0016024)3.37424538
70regulation of Golgi to plasma membrane protein transport (GO:0042996)3.37280056
71protein neddylation (GO:0045116)3.37102782
72pyrimidine ribonucleoside catabolic process (GO:0046133)3.36559529
73regulation of establishment of protein localization to plasma membrane (GO:0090003)3.35961517
74eye photoreceptor cell development (GO:0042462)3.35403867
75myeloid dendritic cell differentiation (GO:0043011)3.31794476
76DNA strand renaturation (GO:0000733)3.31751935
77regulation of calcium-mediated signaling (GO:0050848)3.28933352
78negative regulation of viral release from host cell (GO:1902187)3.17174342
79positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.15166994
80photoreceptor cell development (GO:0042461)3.14694479
81positive regulation of endothelial cell differentiation (GO:0045603)3.07414657
82negative regulation of lymphocyte mediated immunity (GO:0002707)3.07077364
83phosphorelay signal transduction system (GO:0000160)3.03905639
84mitochondrial calcium ion transport (GO:0006851)3.03382420
85cyclic nucleotide catabolic process (GO:0009214)3.02312084
86positive regulation of heart rate (GO:0010460)3.00462523
87UTP metabolic process (GO:0046051)3.00423907
88mast cell degranulation (GO:0043303)2.96441251
89mast cell activation involved in immune response (GO:0002279)2.96441251
90plasma lipoprotein particle assembly (GO:0034377)2.96159097
91negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.96110304
92regulation of leukocyte mediated cytotoxicity (GO:0001910)2.95328311
93UTP biosynthetic process (GO:0006228)2.93769268
94negative regulation of oxidoreductase activity (GO:0051354)2.93570586
95regulation of ARF GTPase activity (GO:0032312)2.93212806
96replication fork processing (GO:0031297)2.91150235
97GTP biosynthetic process (GO:0006183)2.84272849
98CDP-diacylglycerol metabolic process (GO:0046341)2.84003011
99positive regulation of humoral immune response (GO:0002922)2.81492560
100myeloid dendritic cell activation (GO:0001773)2.80364411

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse6.70968949
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse6.14839185
3E2F7_22180533_ChIP-Seq_HELA_Human3.30265393
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.28986523
5STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.95142416
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.93901855
7RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.40334499
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.15504298
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.15404632
10BP1_19119308_ChIP-ChIP_Hs578T_Human15.8584174
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.93990608
12EZH2_22144423_ChIP-Seq_EOC_Human1.87938471
13SMAD3_21741376_ChIP-Seq_HESCs_Human1.56768765
14ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53040612
15SCL_19346495_ChIP-Seq_HPC-7_Human1.46094152
16BCAT_22108803_ChIP-Seq_LS180_Human1.41513681
17STAT4_19710469_ChIP-ChIP_TH1__Mouse1.37566403
18SMAD3_21741376_ChIP-Seq_EPCs_Human1.34006423
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.29495409
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.23209339
21CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.19547919
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.17607703
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17166250
24GATA3_21878914_ChIP-Seq_MCF-7_Human1.16807718
25PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.12289833
26GATA3_21867929_ChIP-Seq_TH1_Mouse1.11943753
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.07845069
28CTBP2_25329375_ChIP-Seq_LNCAP_Human0.97025877
29ELF5_23300383_ChIP-Seq_T47D_Human0.96350373
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95655436
31TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94749288
32IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.93540290
33ELF1_17652178_ChIP-ChIP_JURKAT_Human0.93159310
34FOXH1_21741376_ChIP-Seq_EPCs_Human0.92051882
35CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91775532
36P53_22387025_ChIP-Seq_ESCs_Mouse0.91071770
37CMYC_18555785_Chip-Seq_ESCs_Mouse0.90797040
38SUZ12_18555785_Chip-Seq_ESCs_Mouse0.87506019
39EST1_17652178_ChIP-ChIP_JURKAT_Human0.86862088
40ZFP57_27257070_Chip-Seq_ESCs_Mouse0.86673842
41EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.86609444
42UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86458747
43TCF4_22108803_ChIP-Seq_LS180_Human0.85384353
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85113977
45SMAD4_21799915_ChIP-Seq_A2780_Human0.84845513
46PCGF2_27294783_Chip-Seq_ESCs_Mouse0.84819141
47CDX2_22108803_ChIP-Seq_LS180_Human0.81882805
48ER_23166858_ChIP-Seq_MCF-7_Human0.81561018
49ELK1_19687146_ChIP-ChIP_HELA_Human0.81428293
50NMYC_18555785_Chip-Seq_ESCs_Mouse0.81263362
51GATA3_26560356_Chip-Seq_TH2_Human0.80994595
52MYB_26560356_Chip-Seq_TH1_Human0.80663771
53FOXA1_27270436_Chip-Seq_PROSTATE_Human0.80595400
54FOXA1_25329375_ChIP-Seq_VCAP_Human0.80595400
55E2F1_18555785_Chip-Seq_ESCs_Mouse0.80531247
56SRF_21415370_ChIP-Seq_HL-1_Mouse0.80528798
57NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.80211980
58SMAD4_21741376_ChIP-Seq_HESCs_Human0.79987015
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.79802984
60ZNF263_19887448_ChIP-Seq_K562_Human0.79419203
61WT1_19549856_ChIP-ChIP_CCG9911_Human0.79042244
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.78099116
63CBP_20019798_ChIP-Seq_JUKART_Human0.78099116
64TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.76822638
65PCGF2_27294783_Chip-Seq_NPCs_Mouse0.76746141
66TAF2_19829295_ChIP-Seq_ESCs_Human0.75889728
67CBP_21632823_ChIP-Seq_H3396_Human0.75881753
68SMAD4_21741376_ChIP-Seq_EPCs_Human0.75457240
69PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.75338027
70HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.74680847
71ETV2_25802403_ChIP-Seq_MESCs_Mouse0.74204889
72P300_18555785_Chip-Seq_ESCs_Mouse0.73664001
73IRF1_19129219_ChIP-ChIP_H3396_Human0.73509058
74HOXB4_20404135_ChIP-ChIP_EML_Mouse0.73403562
75NFE2_27457419_Chip-Seq_LIVER_Mouse0.72615716
76PRDM14_20953172_ChIP-Seq_ESCs_Human0.71678788
77FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.71659153
78GBX2_23144817_ChIP-Seq_PC3_Human0.71384479
79STAT3_23295773_ChIP-Seq_U87_Human0.70947394
80POU3F2_20337985_ChIP-ChIP_501MEL_Human0.70218104
81TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.69670551
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.69664171
83SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.69396447
84SOX9_26525672_Chip-Seq_HEART_Mouse0.69340398
85RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.69064056
86STAT3_18555785_Chip-Seq_ESCs_Mouse0.68223034
87CBX2_22325352_ChIP-Seq_293T-Rex_Human0.67433947
88EGR1_23403033_ChIP-Seq_LIVER_Mouse0.66397648
89GATA4_25053715_ChIP-Seq_YYC3_Human0.65893124
90EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.65545973
91RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.65160385
92SMAD1_18555785_Chip-Seq_ESCs_Mouse0.64958622
93RBPJ_21746931_ChIP-Seq_IB4_Human0.63441274
94GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.63388360
95RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.62966750
96TDRD3_21172665_ChIP-Seq_MCF-7_Human0.62707014
97P53_22127205_ChIP-Seq_FIBROBLAST_Human0.62574909
98NANOG_18555785_Chip-Seq_ESCs_Mouse0.61934667
99P300_19829295_ChIP-Seq_ESCs_Human0.61632592
100SUZ12_27294783_Chip-Seq_NPCs_Mouse0.61597138

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology7.84852727
2MP0002822_catalepsy3.91773256
3MP0009333_abnormal_splenocyte_physiolog3.85681506
4MP0003436_decreased_susceptibility_to3.52611662
5MP0001346_abnormal_lacrimal_gland2.82282429
6MP0001501_abnormal_sleep_pattern2.63683493
7MP0005551_abnormal_eye_electrophysiolog2.63432034
8MP0004145_abnormal_muscle_electrophysio2.52594284
9MP0000569_abnormal_digit_pigmentation2.46240984
10MP0004742_abnormal_vestibular_system2.30913545
11MP0001835_abnormal_antigen_presentation2.28904509
12MP0000371_diluted_coat_color2.14752646
13MP0001986_abnormal_taste_sensitivity2.13305906
14MP0005253_abnormal_eye_physiology2.11172486
15MP0008775_abnormal_heart_ventricle2.10592914
16MP0003950_abnormal_plasma_membrane1.98740289
17MP0005367_renal/urinary_system_phenotyp1.98504863
18MP0000516_abnormal_urinary_system1.98504863
19MP0002148_abnormal_hypersensitivity_rea1.93002026
20MP0001324_abnormal_eye_pigmentation1.83182430
21MP0001299_abnormal_eye_distance/1.78189865
22MP0004510_myositis1.69586828
23MP0002272_abnormal_nervous_system1.64953270
24MP0004957_abnormal_blastocyst_morpholog1.63236443
25MP0005671_abnormal_response_to1.59075875
26MP0002234_abnormal_pharynx_morphology1.58440760
27MP0005195_abnormal_posterior_eye1.57351002
28MP0002751_abnormal_autonomic_nervous1.55012705
29MP0000749_muscle_degeneration1.54419171
30MP0005248_abnormal_Harderian_gland1.54150321
31MP0008875_abnormal_xenobiotic_pharmacok1.43699769
32MP0005387_immune_system_phenotype1.38423082
33MP0001790_abnormal_immune_system1.38423082
34MP0005391_vision/eye_phenotype1.36157727
35MP0006072_abnormal_retinal_apoptosis1.35418440
36MP0001800_abnormal_humoral_immune1.32254457
37MP0000015_abnormal_ear_pigmentation1.30715226
38MP0002177_abnormal_outer_ear1.25081344
39MP0001666_abnormal_nutrient_absorption1.22012882
40MP0001727_abnormal_embryo_implantation1.20901628
41MP0003866_abnormal_defecation1.18616298
42MP0003806_abnormal_nucleotide_metabolis1.17920287
43MP0008007_abnormal_cellular_replicative1.14496497
44MP0003172_abnormal_lysosome_physiology1.12662599
45MP0001486_abnormal_startle_reflex1.11024101
46MP0005670_abnormal_white_adipose1.10787052
47MP0001873_stomach_inflammation1.07709770
48MP0002752_abnormal_somatic_nervous1.07072464
49MP0009745_abnormal_behavioral_response1.04074209
50MP0004142_abnormal_muscle_tone1.02302991
51MP0003638_abnormal_response/metabolism_1.01871356
52MP0003763_abnormal_thymus_physiology1.00807621
53MP0001963_abnormal_hearing_physiology0.98662263
54MP0001851_eye_inflammation0.96394473
55MP0005000_abnormal_immune_tolerance0.96329124
56MP0008789_abnormal_olfactory_epithelium0.95645884
57MP0003123_paternal_imprinting0.94448752
58MP0002735_abnormal_chemical_nociception0.93810975
59MP0003943_abnormal_hepatobiliary_system0.93040483
60MP0008004_abnormal_stomach_pH0.92569444
61MP0004484_altered_response_of0.92172005
62MP0003252_abnormal_bile_duct0.92106899
63MP0004043_abnormal_pH_regulation0.91976923
64MP0008872_abnormal_physiological_respon0.91417298
65MP0009764_decreased_sensitivity_to0.89408616
66MP0003786_premature_aging0.88281608
67MP0002420_abnormal_adaptive_immunity0.86648287
68MP0002697_abnormal_eye_size0.84919675
69MP0001919_abnormal_reproductive_system0.84156692
70MP0005193_abnormal_anterior_eye0.81973761
71MP0001819_abnormal_immune_cell0.81448251
72MP0000462_abnormal_digestive_system0.80405756
73MP0010030_abnormal_orbit_morphology0.80250098
74MP0000026_abnormal_inner_ear0.79975546
75MP0002102_abnormal_ear_morphology0.78515914
76MP0005379_endocrine/exocrine_gland_phen0.78486940
77MP0002229_neurodegeneration0.77341681
78MP0004233_abnormal_muscle_weight0.77104704
79MP0002184_abnormal_innervation0.75057772
80MP0005165_increased_susceptibility_to0.74467317
81MP0005464_abnormal_platelet_physiology0.74277245
82MP0002398_abnormal_bone_marrow0.74179814
83MP0003111_abnormal_nucleus_morphology0.73572119
84MP0002452_abnormal_antigen_presenting0.73534280
85MP0002723_abnormal_immune_serum0.72396683
86MP0002877_abnormal_melanocyte_morpholog0.70960193
87MP0003890_abnormal_embryonic-extraembry0.70143640
88MP0004808_abnormal_hematopoietic_stem0.69931577
89MP0008873_increased_physiological_sensi0.69823962
90MP0002210_abnormal_sex_determination0.69628637
91MP0001663_abnormal_digestive_system0.67674947
92MP0002736_abnormal_nociception_after0.66597881
93MP0002139_abnormal_hepatobiliary_system0.64869817
94MP0003183_abnormal_peptide_metabolism0.64381031
95MP0001286_abnormal_eye_development0.62479543
96MP0003693_abnormal_embryo_hatching0.62188464
97MP0002405_respiratory_system_inflammati0.61639949
98MP0001502_abnormal_circadian_rhythm0.60983238
99MP0005197_abnormal_uvea_morphology0.60978426
100MP0000689_abnormal_spleen_morphology0.59733521

Predicted human phenotypes

RankGene SetZ-score
1Hyperalaninemia (HP:0003348)8.03616003
2Abnormality of pyruvate family amino acid metabolism (HP:0010915)8.03616003
3Abnormality of alanine metabolism (HP:0010916)8.03616003
4Posterior subcapsular cataract (HP:0007787)7.40323579
5Fair hair (HP:0002286)5.98492928
6Alacrima (HP:0000522)5.17282275
7Chorioretinal atrophy (HP:0000533)4.94589076
8Generalized hypopigmentation of hair (HP:0011358)4.70615083
9Mild short stature (HP:0003502)4.61152317
10Subcapsular cataract (HP:0000523)4.36698590
11Decreased lacrimation (HP:0000633)4.23801155
12Orthostatic hypotension (HP:0001278)4.17471924
13Tetraparesis (HP:0002273)4.04257650
14Abolished electroretinogram (ERG) (HP:0000550)3.87398743
15T lymphocytopenia (HP:0005403)3.68083725
163-Methylglutaconic aciduria (HP:0003535)3.66004433
17Bony spicule pigmentary retinopathy (HP:0007737)3.63691489
18Hyperlipoproteinemia (HP:0010980)3.58973167
19Central scotoma (HP:0000603)3.53176143
20Dysautonomia (HP:0002459)3.49895292
21Abnormality of T cell number (HP:0011839)3.31731610
22Intestinal atresia (HP:0011100)3.21181247
23Scotoma (HP:0000575)3.11542444
24Congenital sensorineural hearing impairment (HP:0008527)3.08819536
25Pendular nystagmus (HP:0012043)3.07425199
26Microretrognathia (HP:0000308)3.04275291
27Attenuation of retinal blood vessels (HP:0007843)3.01772334
28Absent rod-and cone-mediated responses on ERG (HP:0007688)2.95126733
29Abnormality of DNA repair (HP:0003254)2.95123545
30Spinal muscular atrophy (HP:0007269)2.81508719
31Volvulus (HP:0002580)2.76302428
32Abnormality of T cells (HP:0002843)2.71766654
33Entropion (HP:0000621)2.66799613
34Increased corneal curvature (HP:0100692)2.62612152
35Keratoconus (HP:0000563)2.62612152
36Polar cataract (HP:0010696)2.57763626
37Aplasia cutis congenita (HP:0001057)2.57676455
38Encephalitis (HP:0002383)2.54986097
39Abnormal delayed hypersensitivity skin test (HP:0002963)2.54910298
40Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.53902386
41Glucose intolerance (HP:0000833)2.52043858
42Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.50971109
43Oligodactyly (hands) (HP:0001180)2.50023319
44Abnormality of T cell physiology (HP:0011840)2.48319905
45Abnormality of the renal medulla (HP:0100957)2.47506956
46Congenital stationary night blindness (HP:0007642)2.44865035
47Abnormal hair whorl (HP:0010721)2.43989851
48Recurrent viral infections (HP:0004429)2.42727025
49Blue irides (HP:0000635)2.38592674
50Hypomagnesemia (HP:0002917)2.32953629
51Type II diabetes mellitus (HP:0005978)2.32501817
52Abnormality of the phalanges of the 5th finger (HP:0004213)2.31178007
53Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.30566160
54Abnormal pancreas size (HP:0012094)2.26071341
55Hypoplastic nipples (HP:0002557)2.21399042
56Ectopic kidney (HP:0000086)2.20444964
57Nephroblastoma (Wilms tumor) (HP:0002667)2.18870801
58Abnormal autonomic nervous system physiology (HP:0012332)2.15517616
59Embryonal renal neoplasm (HP:0011794)2.15039562
60Nephronophthisis (HP:0000090)2.14354393
61Panhypogammaglobulinemia (HP:0003139)2.12908995
62Flat occiput (HP:0005469)2.11451485
63Constricted visual fields (HP:0001133)2.06534463
64Poikiloderma (HP:0001029)2.05553294
65Spinal cord lesions (HP:0100561)2.05131303
66Syringomyelia (HP:0003396)2.05131303
67Photophobia (HP:0000613)2.04084588
68Thyroid-stimulating hormone excess (HP:0002925)1.98760396
69Abnormality of magnesium homeostasis (HP:0004921)1.97356233
70Abnormal glucose tolerance (HP:0001952)1.93819622
71Abnormality of the labia minora (HP:0012880)1.92713078
72Subaortic stenosis (HP:0001682)1.92542319
73Abnormality of the left ventricular outflow tract (HP:0011103)1.92542319
74Viral hepatitis (HP:0006562)1.91551204
75Limited elbow extension (HP:0001377)1.91302122
76Increased circulating renin level (HP:0000848)1.90591014
77Abnormality of the renal cortex (HP:0011035)1.90106167
78Increased nuchal translucency (HP:0010880)1.89389819
79Chronic mucocutaneous candidiasis (HP:0002728)1.88396642
80Recurrent cutaneous fungal infections (HP:0011370)1.88396642
81Spinal canal stenosis (HP:0003416)1.88136000
82Delayed CNS myelination (HP:0002188)1.87107533
83Late onset (HP:0003584)1.85033420
84Aplasia/Hypoplasia of the tongue (HP:0010295)1.84623232
85Abnormality of serum amino acid levels (HP:0003112)1.79035407
86Abnormal rod and cone electroretinograms (HP:0008323)1.75226815
87Hypoproteinemia (HP:0003075)1.74919217
88Rectovaginal fistula (HP:0000143)1.71295726
89Rectal fistula (HP:0100590)1.71295726
90Abnormality of the phalanges of the 2nd finger (HP:0009541)1.70750976
91Microglossia (HP:0000171)1.68757271
92Pancreatic cysts (HP:0001737)1.67121466
93Primary adrenal insufficiency (HP:0008207)1.64655471
94Nasal speech (HP:0001611)1.64587264
95Pancreatic fibrosis (HP:0100732)1.62816279
96Pulmonary fibrosis (HP:0002206)1.61136719
97Supernumerary bones of the axial skeleton (HP:0009144)1.61083592
98Severe visual impairment (HP:0001141)1.59849415
99Decreased central vision (HP:0007663)1.59816874
100Abnormality of small intestinal villus morphology (HP:0011472)1.58976188

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.64780219
2STK395.48666754
3WNK45.14532044
4SCYL24.75922310
5RIPK43.93020556
6TLK13.42785872
7MST43.22596371
8TRPM72.91056612
9BMPR22.85459206
10PIK3CG2.37111343
11SIK32.24081207
12OXSR12.20018728
13CAMK42.15959743
14TXK2.02909955
15MARK31.88382359
16SIK21.72062640
17WNK11.66095982
18MAP3K121.64482287
19TAOK31.58931256
20DYRK31.57314924
21ERBB41.54176512
22CAMK11.47201420
23ALK1.33183474
24TAF11.32416426
25SIK11.31348981
26NME21.31161398
27SRPK11.26261846
28OBSCN1.20860614
29RPS6KA41.12767053
30PAK41.12292525
31PINK11.07487209
32IRAK41.00413405
33MYLK0.92450641
34MAP4K20.86864031
35CAMK2A0.76998484
36SGK2230.75526597
37SGK4940.75526597
38WNK30.74183670
39CDK190.71446420
40ZAK0.68745330
41SGK20.66484041
42VRK20.66424907
43ILK0.63017573
44ADRBK20.62066015
45CAMK2D0.60211326
46HIPK20.59934352
47CAMK2B0.52318474
48MAP3K80.51673273
49CSNK1A1L0.51425112
50ATR0.48429895
51JAK10.47644640
52EPHA20.47443536
53DAPK20.46631807
54PRKD10.46524924
55TSSK60.46414672
56CSNK1G30.46124618
57NEK20.44516849
58PAK60.44289958
59CAMK2G0.42840674
60PBK0.42839742
61PTK2B0.38157437
62CSNK1G20.37314521
63BRAF0.37155651
64PDGFRA0.36241479
65DAPK10.35843889
66ATM0.35464572
67MAPKAPK50.35127026
68ABL20.34146345
69PLK20.33474693
70MARK20.33034829
71DYRK1B0.31154603
72CSNK1G10.30207093
73CAMKK20.29376190
74TEC0.28552804
75ERBB30.27718013
76PDGFRB0.27217507
77CSNK1D0.25318247
78PRKCQ0.25098801
79BCR0.23717364
80IRAK30.23680085
81AKT10.23250137
82PRKCZ0.21733001
83VRK10.21106838
84MTOR0.20957447
85ROCK20.19294860
86PRKCB0.17118417
87IGF1R0.16490930
88EPHB20.15213501
89INSRR0.14059724
90ABL10.13942579
91GSK3A0.13829122
92RPS6KA50.12692685
93ERBB20.12507280
94DAPK30.12312010
95MAPK100.12111315
96MAP3K40.11339455
97DYRK20.11296281
98CHEK10.11221257
99MAP3K30.09662527
100KDR0.08996134

Predicted pathways (KEGG)

RankGene SetZ-score
1Cytosolic DNA-sensing pathway_Homo sapiens_hsa046233.87348082
2RNA polymerase_Homo sapiens_hsa030203.84050905
3Protein export_Homo sapiens_hsa030602.90644596
4alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.84086669
5One carbon pool by folate_Homo sapiens_hsa006702.67445549
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.61347659
7Primary immunodeficiency_Homo sapiens_hsa053402.46448822
8Phototransduction_Homo sapiens_hsa047442.45866276
9Linoleic acid metabolism_Homo sapiens_hsa005912.40284296
10VEGF signaling pathway_Homo sapiens_hsa043702.25819344
11Cyanoamino acid metabolism_Homo sapiens_hsa004602.20783334
12Amphetamine addiction_Homo sapiens_hsa050312.15476507
13Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.99746683
14Glutamatergic synapse_Homo sapiens_hsa047241.93210225
15RNA degradation_Homo sapiens_hsa030181.90636779
16Morphine addiction_Homo sapiens_hsa050321.85184564
17Antigen processing and presentation_Homo sapiens_hsa046121.74976394
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.73307981
19Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.71190721
20Pyrimidine metabolism_Homo sapiens_hsa002401.67907983
21Cocaine addiction_Homo sapiens_hsa050301.65214042
22Hematopoietic cell lineage_Homo sapiens_hsa046401.64492718
23Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.61420929
24Oxidative phosphorylation_Homo sapiens_hsa001901.61127429
25Circadian rhythm_Homo sapiens_hsa047101.57911851
26Ovarian steroidogenesis_Homo sapiens_hsa049131.56903486
27T cell receptor signaling pathway_Homo sapiens_hsa046601.56670957
28Parkinsons disease_Homo sapiens_hsa050121.47883865
29Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.46089692
30Alzheimers disease_Homo sapiens_hsa050101.35472915
31Ether lipid metabolism_Homo sapiens_hsa005651.25397386
32Arachidonic acid metabolism_Homo sapiens_hsa005901.25153223
33Proteasome_Homo sapiens_hsa030501.24290054
34Salmonella infection_Homo sapiens_hsa051321.21430395
35Long-term potentiation_Homo sapiens_hsa047201.14929398
36Measles_Homo sapiens_hsa051621.13698948
37Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.12937514
38Type I diabetes mellitus_Homo sapiens_hsa049401.10541750
39Chemokine signaling pathway_Homo sapiens_hsa040621.03973272
40Purine metabolism_Homo sapiens_hsa002301.00453689
41Circadian entrainment_Homo sapiens_hsa047130.95989581
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.90794398
43Oxytocin signaling pathway_Homo sapiens_hsa049210.90615539
44ABC transporters_Homo sapiens_hsa020100.88523999
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.86604646
46Serotonergic synapse_Homo sapiens_hsa047260.83799134
47Regulation of autophagy_Homo sapiens_hsa041400.82460898
48Glycerophospholipid metabolism_Homo sapiens_hsa005640.80841535
49Alcoholism_Homo sapiens_hsa050340.76959738
50Dopaminergic synapse_Homo sapiens_hsa047280.76805980
51Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76416821
52Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73169771
53Long-term depression_Homo sapiens_hsa047300.69810292
54Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69760232
55Huntingtons disease_Homo sapiens_hsa050160.69304719
56GABAergic synapse_Homo sapiens_hsa047270.67521274
57Fatty acid biosynthesis_Homo sapiens_hsa000610.67185110
58Renin secretion_Homo sapiens_hsa049240.65216003
59Steroid biosynthesis_Homo sapiens_hsa001000.63904754
60B cell receptor signaling pathway_Homo sapiens_hsa046620.62076517
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60488380
62Cholinergic synapse_Homo sapiens_hsa047250.57543209
63Thyroid hormone synthesis_Homo sapiens_hsa049180.55784380
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54943950
65Nicotine addiction_Homo sapiens_hsa050330.53952289
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.53372493
67Folate biosynthesis_Homo sapiens_hsa007900.52877943
68cAMP signaling pathway_Homo sapiens_hsa040240.51904754
69Insulin secretion_Homo sapiens_hsa049110.51271757
70Salivary secretion_Homo sapiens_hsa049700.50784459
71Ras signaling pathway_Homo sapiens_hsa040140.50021846
72Fructose and mannose metabolism_Homo sapiens_hsa000510.49845087
73Endocytosis_Homo sapiens_hsa041440.49073410
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48463816
75Mineral absorption_Homo sapiens_hsa049780.48251087
76Taste transduction_Homo sapiens_hsa047420.47898208
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.47539250
78Nitrogen metabolism_Homo sapiens_hsa009100.47242405
79Cardiac muscle contraction_Homo sapiens_hsa042600.43960832
80RNA transport_Homo sapiens_hsa030130.41800945
81Ribosome_Homo sapiens_hsa030100.41780155
82Inositol phosphate metabolism_Homo sapiens_hsa005620.41157760
83Non-homologous end-joining_Homo sapiens_hsa034500.41109814
84p53 signaling pathway_Homo sapiens_hsa041150.40564878
85Oocyte meiosis_Homo sapiens_hsa041140.39510045
86Autoimmune thyroid disease_Homo sapiens_hsa053200.38941198
87Osteoclast differentiation_Homo sapiens_hsa043800.37563677
88Non-small cell lung cancer_Homo sapiens_hsa052230.36819704
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34743951
90Amoebiasis_Homo sapiens_hsa051460.32677616
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31627914
92GnRH signaling pathway_Homo sapiens_hsa049120.29297745
93Graft-versus-host disease_Homo sapiens_hsa053320.29149141
94Small cell lung cancer_Homo sapiens_hsa052220.28833873
95Vibrio cholerae infection_Homo sapiens_hsa051100.27940183
96Gastric acid secretion_Homo sapiens_hsa049710.27354019
97Prion diseases_Homo sapiens_hsa050200.26680868
98Peroxisome_Homo sapiens_hsa041460.24693930
99HTLV-I infection_Homo sapiens_hsa051660.24627296
100Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.24353232

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »