TMEM214

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1COPI coating of Golgi vesicle (GO:0048205)7.53473750
2Golgi transport vesicle coating (GO:0048200)7.53473750
3maintenance of protein localization in endoplasmic reticulum (GO:0035437)6.63530265
4protein retention in ER lumen (GO:0006621)6.28372905
5COPII vesicle coating (GO:0048208)5.19757562
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.00971652
7L-phenylalanine catabolic process (GO:0006559)5.00971652
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.00376340
9L-phenylalanine metabolic process (GO:0006558)5.00376340
10activation of signaling protein activity involved in unfolded protein response (GO:0006987)4.88188715
11exocrine pancreas development (GO:0031017)4.85875591
124-hydroxyproline metabolic process (GO:0019471)4.81017424
13intestinal cholesterol absorption (GO:0030299)4.66990009
14positive regulation of nuclease activity (GO:0032075)4.63574213
15retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)4.58643406
16sulfur amino acid catabolic process (GO:0000098)4.40322315
17proline biosynthetic process (GO:0006561)4.40265705
18skin morphogenesis (GO:0043589)4.28814962
19cysteine metabolic process (GO:0006534)4.25963769
20endoplasmic reticulum unfolded protein response (GO:0030968)4.23745825
21peptidyl-glutamic acid carboxylation (GO:0017187)4.16256005
22protein carboxylation (GO:0018214)4.16256005
23regulation of nuclease activity (GO:0032069)4.15487298
24cellular response to unfolded protein (GO:0034620)4.12566151
25triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.03128305
26basement membrane organization (GO:0071711)3.99116458
27ER-nucleus signaling pathway (GO:0006984)3.97103389
28valine metabolic process (GO:0006573)3.93714402
29aromatic amino acid family catabolic process (GO:0009074)3.91804245
30negative regulation of fibrinolysis (GO:0051918)3.87377341
31cellular response to topologically incorrect protein (GO:0035967)3.86124997
32alpha-linolenic acid metabolic process (GO:0036109)3.82535567
33homocysteine metabolic process (GO:0050667)3.79112456
34glyoxylate metabolic process (GO:0046487)3.76920471
35regulation of cholesterol homeostasis (GO:2000188)3.72258915
36lysine metabolic process (GO:0006553)3.71175615
37lysine catabolic process (GO:0006554)3.71175615
38cellular modified amino acid catabolic process (GO:0042219)3.70092525
39high-density lipoprotein particle remodeling (GO:0034375)3.64865957
40vesicle coating (GO:0006901)3.64133754
41regulation of early endosome to late endosome transport (GO:2000641)3.60164634
42proline metabolic process (GO:0006560)3.55642076
43urea cycle (GO:0000050)3.55633620
44urea metabolic process (GO:0019627)3.55633620
45response to endoplasmic reticulum stress (GO:0034976)3.51166049
46mannose metabolic process (GO:0006013)3.50301181
47regulation of fibrinolysis (GO:0051917)3.48863939
48reverse cholesterol transport (GO:0043691)3.46721234
49ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.41314568
50regulation of extracellular matrix disassembly (GO:0010715)3.40924109
51pinocytosis (GO:0006907)3.39153705
52regulation of protein activation cascade (GO:2000257)3.38772041
53cell-substrate junction assembly (GO:0007044)3.38083169
54peptidyl-proline hydroxylation (GO:0019511)3.37375741
55positive regulation of extracellular matrix organization (GO:1903055)3.35414096
56response to unfolded protein (GO:0006986)3.35298248
57fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.29681079
58L-alpha-amino acid transmembrane transport (GO:1902475)3.25635300
59complement activation, alternative pathway (GO:0006957)3.24089391
60nitrogen cycle metabolic process (GO:0071941)3.23425323
61response to topologically incorrect protein (GO:0035966)3.21518663
62serine family amino acid catabolic process (GO:0009071)3.21452230
63endodermal cell differentiation (GO:0035987)3.19657381
64regulation of complement activation (GO:0030449)3.19315805
65kynurenine metabolic process (GO:0070189)3.19292307
66triglyceride homeostasis (GO:0070328)3.16991023
67acylglycerol homeostasis (GO:0055090)3.16991023
68glycine metabolic process (GO:0006544)3.16572951
69plasma lipoprotein particle clearance (GO:0034381)3.15456948
70hemidesmosome assembly (GO:0031581)3.15100423
71focal adhesion assembly (GO:0048041)3.14879386
72cell-substrate adherens junction assembly (GO:0007045)3.14879386
73protein localization to endosome (GO:0036010)3.14630791
74desmosome organization (GO:0002934)3.13858095
75bile acid biosynthetic process (GO:0006699)3.13536957
76intestinal absorption (GO:0050892)3.12103846
77regulation of fatty acid beta-oxidation (GO:0031998)3.10867061
78stress fiber assembly (GO:0043149)3.09420382
79adhesion of symbiont to host (GO:0044406)3.09275811
80barbed-end actin filament capping (GO:0051016)3.08257456
81tryptophan metabolic process (GO:0006568)3.07946273
82indolalkylamine catabolic process (GO:0046218)3.07271759
83tryptophan catabolic process (GO:0006569)3.07271759
84indole-containing compound catabolic process (GO:0042436)3.07271759
85adherens junction assembly (GO:0034333)3.06928400
862-oxoglutarate metabolic process (GO:0006103)3.06840946
87plasma lipoprotein particle remodeling (GO:0034369)3.05267987
88protein-lipid complex remodeling (GO:0034368)3.05267987
89macromolecular complex remodeling (GO:0034367)3.05267987
90amino-acid betaine metabolic process (GO:0006577)3.03130971
91serine family amino acid metabolic process (GO:0009069)3.02200389
92regulation of plasminogen activation (GO:0010755)3.00946593
93protein maturation by protein folding (GO:0022417)3.00870581
94cell adhesion mediated by integrin (GO:0033627)3.00373044
95hyaluronan catabolic process (GO:0030214)2.99931157
96serine family amino acid biosynthetic process (GO:0009070)2.98265803
97peptidyl-asparagine modification (GO:0018196)2.97166877
98glutamine family amino acid biosynthetic process (GO:0009084)2.97075522
99protein N-linked glycosylation via asparagine (GO:0018279)2.96529617
100positive regulation of glycolytic process (GO:0045821)2.96385671
101regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.95679924
102protein hydroxylation (GO:0018126)2.94360885
103aspartate family amino acid catabolic process (GO:0009068)2.93834176
104tricarboxylic acid metabolic process (GO:0072350)2.93449640
105lipoprotein metabolic process (GO:0042157)2.93193894
106alpha-amino acid catabolic process (GO:1901606)2.92964330
107endocrine pancreas development (GO:0031018)2.92598345
108cellular amino acid catabolic process (GO:0009063)2.91889205
109positive regulation of fatty acid beta-oxidation (GO:0032000)2.91271693
110protein autoprocessing (GO:0016540)2.90327021
111negative regulation of cholesterol transport (GO:0032375)2.89981949
112negative regulation of sterol transport (GO:0032372)2.89981949
113apoptotic cell clearance (GO:0043277)2.89651285
114aromatic amino acid family metabolic process (GO:0009072)2.89454465
115regulation of triglyceride catabolic process (GO:0010896)2.87634148
116transcytosis (GO:0045056)2.87295022
117bile acid metabolic process (GO:0008206)2.87137148
118one-carbon metabolic process (GO:0006730)2.86898617
119regulation of glucose import in response to insulin stimulus (GO:2001273)2.86559024
120tyrosine metabolic process (GO:0006570)2.84964187
121positive regulation of blood vessel endothelial cell migration (GO:0043536)2.83860966
122GDP-mannose metabolic process (GO:0019673)2.83231119
123collagen fibril organization (GO:0030199)2.82999457
124positive regulation of triglyceride metabolic process (GO:0090208)2.82621257
125epithelial cell-cell adhesion (GO:0090136)2.81828948
126regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.80591768
127low-density lipoprotein particle clearance (GO:0034383)2.80109812
128cholesterol catabolic process (GO:0006707)2.79811944
129negative regulation of fatty acid transport (GO:2000192)2.74759833
130glucose 6-phosphate metabolic process (GO:0051156)2.73267671
131regulation of apoptotic process involved in morphogenesis (GO:1902337)2.71972419
132regulation of extracellular matrix organization (GO:1903053)2.68080172
133protein heterotrimerization (GO:0070208)2.67521633
134positive regulation of endothelial cell apoptotic process (GO:2000353)2.65870952
135virion attachment to host cell (GO:0019062)2.64381901
136adhesion of symbiont to host cell (GO:0044650)2.64381901
137positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.61343997
138regulation of apoptotic cell clearance (GO:2000425)2.61160490
139positive regulation of Cdc42 GTPase activity (GO:0043089)2.60091492
140embryonic process involved in female pregnancy (GO:0060136)2.58456869
141embryo implantation (GO:0007566)2.56689782
142response to laminar fluid shear stress (GO:0034616)2.54873053
143planar cell polarity pathway involved in neural tube closure (GO:0090179)2.51217348
144negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.49784967
145branching involved in mammary gland duct morphogenesis (GO:0060444)2.49175157
146negative regulation of erythrocyte differentiation (GO:0045647)2.47511927
147apoptotic process involved in morphogenesis (GO:0060561)2.46811749
148positive regulation of osteoblast proliferation (GO:0033690)2.46495621
149vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.46248438
150collagen metabolic process (GO:0032963)2.42957671
151protein-lipid complex assembly (GO:0065005)2.41944824
152positive regulation of receptor recycling (GO:0001921)2.41446639
153maternal placenta development (GO:0001893)2.39686300
154hypotonic response (GO:0006971)2.38352864
155extracellular matrix disassembly (GO:0022617)2.37337743
156activation of Rac GTPase activity (GO:0032863)2.36945801
157hyaluronan metabolic process (GO:0030212)2.36425247
158negative regulation of cell size (GO:0045792)2.35333984
159pentose-phosphate shunt (GO:0006098)2.34611786
160regulation of cholesterol biosynthetic process (GO:0045540)2.30647556
161multicellular organismal macromolecule metabolic process (GO:0044259)2.29902753
162negative regulation of protein localization to plasma membrane (GO:1903077)2.29886739
163semaphorin-plexin signaling pathway (GO:0071526)2.29747654
164plasma lipoprotein particle assembly (GO:0034377)2.29663702
165collagen catabolic process (GO:0030574)2.27479123
166regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.27137565
167vascular endothelial growth factor signaling pathway (GO:0038084)2.26687150
168very-low-density lipoprotein particle assembly (GO:0034379)2.26433641
169cytoskeletal anchoring at plasma membrane (GO:0007016)2.25817578
170regulation of metalloenzyme activity (GO:0048552)2.25252894
171fibril organization (GO:0097435)2.25090309
172nucleotide-sugar biosynthetic process (GO:0009226)2.22100958

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.24531622
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.22627401
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.80194156
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.11380015
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.62891365
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.23855411
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.79727697
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.64992757
9EGR1_23403033_ChIP-Seq_LIVER_Mouse2.59292083
10TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.35567402
11ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.33254607
12CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.27567225
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.26606612
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.22622379
15CLOCK_20551151_ChIP-Seq_293T_Human2.22099864
16VDR_21846776_ChIP-Seq_THP-1_Human1.99983663
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.97395561
18LXR_22292898_ChIP-Seq_THP-1_Human1.92645624
19TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.86674741
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.78492857
21KDM2B_26808549_Chip-Seq_SUP-B15_Human1.78335583
22TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.76945496
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.74357152
24GATA1_22025678_ChIP-Seq_K562_Human1.66858873
25TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.63190166
26DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.58001508
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.54999929
28UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.53411836
29HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.52733350
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.50840638
31RACK7_27058665_Chip-Seq_MCF-7_Human1.48470857
32SOX2_27498859_Chip-Seq_STOMACH_Mouse1.47252562
33KDM2B_26808549_Chip-Seq_DND41_Human1.46169441
34TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44938067
35KDM2B_26808549_Chip-Seq_K562_Human1.40036451
36ESR2_21235772_ChIP-Seq_MCF-7_Human1.38907397
37TET1_21451524_ChIP-Seq_MESCs_Mouse1.37637064
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.37144893
39TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.35789924
40EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.35257584
41FOXA2_19822575_ChIP-Seq_HepG2_Human1.33228401
42ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.31508083
43KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31194907
44ATF3_27146783_Chip-Seq_COLON_Human1.29917148
45TRIM28_21343339_ChIP-Seq_HEK293_Human1.29719051
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29450524
47WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.28679001
48MYC_22102868_ChIP-Seq_BL_Human1.27694240
49CTCF_27219007_Chip-Seq_ERYTHROID_Human1.27395397
50ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.24878787
51NFIB_24661679_ChIP-Seq_LUNG_Mouse1.24581962
52ELK3_25401928_ChIP-Seq_HUVEC_Human1.24293744
53NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.23658394
54ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23631913
55P68_20966046_ChIP-Seq_HELA_Human1.21980890
56ESR1_21235772_ChIP-Seq_MCF-7_Human1.21424694
57HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.21315560
58VDR_24763502_ChIP-Seq_THP-1_Human1.20189613
59NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.19772781
60ELF1_20517297_ChIP-Seq_JURKAT_Human1.19563813
61RARA_24833708_ChIP-Seq_LIVER_Mouse1.17591945
62BRD4_27068464_Chip-Seq_AML-cells_Mouse1.16536800
63KLF4_18555785_ChIP-Seq_MESCs_Mouse1.16167863
64UBF1/2_26484160_Chip-Seq_HMECs_Human1.15459431
65TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14733909
66MAF_26560356_Chip-Seq_TH1_Human1.14644001
67GATA6_25053715_ChIP-Seq_YYC3_Human1.14064299
68NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.13748618
69CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.12707812
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12453217
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11416247
72HNF4A_19822575_ChIP-Seq_HepG2_Human1.11321891
73GATA4_25053715_ChIP-Seq_YYC3_Human1.10903485
74* TBX20_22328084_ChIP-Seq_HEART_Mouse1.10780070
75* TBX20_22080862_ChIP-Seq_HEART_Mouse1.10780070
76KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10654585
77SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10291542
78RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.10262982
79GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09767879
80RXRA_24833708_ChIP-Seq_LIVER_Mouse1.09253343
81STAT3_1855785_ChIP-Seq_MESCs_Mouse1.07942452
82RARB_24833708_ChIP-Seq_LIVER_Mouse1.07924271
83MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.07801806
84TP63_17297297_ChIP-ChIP_HaCaT_Human1.06648669
85CREB1_26743006_Chip-Seq_LNCaP_Human1.06300126
86SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.04881460
87E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.04812367
88NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.04026111
89P63_26484246_Chip-Seq_KERATINOCYTES_Human1.03928208
90PHF8_20622854_ChIP-Seq_HELA_Human1.03847593
91SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.03627761
92PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02558020
93BCOR_27268052_Chip-Seq_Bcells_Human1.01925680
94SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.00429297
95SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00405162
96SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.00380564
97SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.00380564
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00354111
99RUNX1_22412390_ChIP-Seq_EML_Mouse1.00011763
100RUNX1_27514584_Chip-Seq_MCF-7_Human0.99712660
101KDM2B_26808549_Chip-Seq_JURKAT_Human0.99685195
102RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.99220489
103CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98915938
104HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97189282
105TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96915372
106TP63_22573176_ChIP-Seq_HFKS_Human0.96747258
107SMC4_20622854_ChIP-Seq_HELA_Human0.96635326
108MYB_21317192_ChIP-Seq_ERMYB_Mouse0.95261808
109SMC1_22415368_ChIP-Seq_MEFs_Mouse0.94842657
110SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94615262
111PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93385291
112KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92928441
113E2F7_22180533_ChIP-Seq_HELA_Human0.92862110
114POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92564764
115TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.91351104
116THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.89866296
117NCOR1_26117541_ChIP-Seq_K562_Human0.89374333
118CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88651171
119TP53_22127205_ChIP-Seq_IMR90_Human0.88564934
120PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.88421114
121* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87271700
122SA1_27219007_Chip-Seq_ERYTHROID_Human0.86796476
123FOXP1_21924763_ChIP-Seq_HESCs_Human0.86709952
124ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.86678596
125KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.86638779
126ZFX_18555785_ChIP-Seq_MESCs_Mouse0.86625252
127FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.86097112
128SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86016308
129ERG_21242973_ChIP-ChIP_JURKAT_Human0.85747500
130ZNF263_19887448_ChIP-Seq_K562_Human0.84777111
131CTCF_21964334_Chip-Seq_Bcells_Human0.84522341
132TCF7_22412390_ChIP-Seq_EML_Mouse0.83781857
133CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.82833358
134CHD1_26751641_Chip-Seq_LNCaP_Human0.82735669
135EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.82575106
136TBX5_21415370_ChIP-Seq_HL-1_Mouse0.82534137
137GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.82240046
138P300_27058665_Chip-Seq_ZR-75-30cells_Human0.81764858
139NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81328496

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.12308475
2MP0005365_abnormal_bile_salt4.85878365
3MP0005360_urolithiasis4.24490498
4MP0005083_abnormal_biliary_tract3.80067249
5MP0005085_abnormal_gallbladder_physiolo3.59856398
6MP0001666_abnormal_nutrient_absorption3.33079332
7MP0003705_abnormal_hypodermis_morpholog3.13185711
8MP0009840_abnormal_foam_cell2.87710819
9MP0008438_abnormal_cutaneous_collagen2.70716696
10MP0005220_abnormal_exocrine_pancreas2.60652672
11MP0003252_abnormal_bile_duct2.53659298
12MP0005451_abnormal_body_composition2.51828445
13MP0003806_abnormal_nucleotide_metabolis2.43833569
14MP0003195_calcinosis2.41435419
15MP0010329_abnormal_lipoprotein_level2.27850413
16MP0005670_abnormal_white_adipose2.17324229
17MP0005332_abnormal_amino_acid2.03978345
18MP0001958_emphysema2.01203143
19MP0008875_abnormal_xenobiotic_pharmacok2.01187258
20MP0003868_abnormal_feces_composition1.88627521
21MP0005058_abnormal_lysosome_morphology1.86177010
22MP0001944_abnormal_pancreas_morphology1.77557296
23MP0003091_abnormal_cell_migration1.76603094
24MP0003283_abnormal_digestive_organ1.76105031
25MP0000013_abnormal_adipose_tissue1.74637955
26MP0001849_ear_inflammation1.74537054
27MP0004264_abnormal_extraembryonic_tissu1.68559928
28MP0004858_abnormal_nervous_system1.65772768
29MP0000858_altered_metastatic_potential1.65306610
30MP0000609_abnormal_liver_physiology1.64412557
31MP0009643_abnormal_urine_homeostasis1.63561393
32MP0002118_abnormal_lipid_homeostasis1.60406034
33MP0002693_abnormal_pancreas_physiology1.58752676
34MP0002837_dystrophic_cardiac_calcinosis1.57853479
35MP0002138_abnormal_hepatobiliary_system1.50688670
36MP0000767_abnormal_smooth_muscle1.44048159
37MP0005623_abnormal_meninges_morphology1.43509977
38MP0005409_darkened_coat_color1.42519745
39MP0003191_abnormal_cellular_cholesterol1.41449539
40MP0008260_abnormal_autophagy1.41175346
41MP0004019_abnormal_vitamin_homeostasis1.40625901
42MP0003453_abnormal_keratinocyte_physiol1.39230347
43MP0004272_abnormal_basement_membrane1.38393049
44MP0003950_abnormal_plasma_membrane1.36402874
45MP0005319_abnormal_enzyme/_coenzyme1.35376838
46MP0005084_abnormal_gallbladder_morpholo1.33032918
47MP0003436_decreased_susceptibility_to1.32607273
48MP0006054_spinal_hemorrhage1.32021975
49MP0009384_cardiac_valve_regurgitation1.30568429
50MP0002078_abnormal_glucose_homeostasis1.30553768
51MP0010368_abnormal_lymphatic_system1.28107925
52MP0000003_abnormal_adipose_tissue1.27007951
53MP0003566_abnormal_cell_adhesion1.25958972
54MP0002132_abnormal_respiratory_system1.25316884
55MP0002909_abnormal_adrenal_gland1.24951468
56MP0003300_gastrointestinal_ulcer1.24045038
57MP0001348_abnormal_lacrimal_gland1.23208185
58MP0008961_abnormal_basal_metabolism1.22673004
59MP0003279_aneurysm1.20977144
60MP0002796_impaired_skin_barrier1.20721104
61MP0009780_abnormal_chondrocyte_physiolo1.20542305
62MP0002896_abnormal_bone_mineralization1.19846721
63MP0001915_intracranial_hemorrhage1.15502638
64MP0004947_skin_inflammation1.14640928
65MP0002877_abnormal_melanocyte_morpholog1.13532616
66MP0001756_abnormal_urination1.13382373
67MP0003183_abnormal_peptide_metabolism1.12781342
68MP0005275_abnormal_skin_tensile1.10137240
69MP0005375_adipose_tissue_phenotype1.09823174
70MP0003172_abnormal_lysosome_physiology1.09768707
71MP0000598_abnormal_liver_morphology1.05624998
72MP0003303_peritoneal_inflammation1.04945529
73MP0005503_abnormal_tendon_morphology1.04391288
74MP0005508_abnormal_skeleton_morphology1.03051510
75MP0001542_abnormal_bone_strength1.02460951
76MP0005666_abnormal_adipose_tissue1.02352513
77MP0002269_muscular_atrophy1.02089382
78MP0002998_abnormal_bone_remodeling1.01081707
79MP0001243_abnormal_dermal_layer0.99363351
80MP0009672_abnormal_birth_weight0.97639569
81MP0005636_abnormal_mineral_homeostasis0.97066231
82MP0003959_abnormal_lean_body0.96061527
83MP0000751_myopathy0.94505295
84MP0004043_abnormal_pH_regulation0.94182916
85MP0000678_abnormal_parathyroid_gland0.93782432
86MP0005164_abnormal_response_to0.93558754
87MP0005501_abnormal_skin_physiology0.92821786
88MP0002933_joint_inflammation0.92338203
89MP0001765_abnormal_ion_homeostasis0.90757625
90MP0001533_abnormal_skeleton_physiology0.90716728
91MP0003941_abnormal_skin_development0.90619663
92MP0009333_abnormal_splenocyte_physiolog0.89606833
93MP0001764_abnormal_homeostasis0.88232808
94MP0005023_abnormal_wound_healing0.87672222
95MP0005408_hypopigmentation0.86051975
96MP0005448_abnormal_energy_balance0.85226287
97MP0005390_skeleton_phenotype0.85210962
98MP0005464_abnormal_platelet_physiology0.84639511
99MP0001216_abnormal_epidermal_layer0.84525177
100MP0004185_abnormal_adipocyte_glucose0.84047163
101MP0005410_abnormal_fertilization0.82938288
102MP0002089_abnormal_postnatal_growth/wei0.82739855
103MP0005621_abnormal_cell_physiology0.81625858
104MP0004782_abnormal_surfactant_physiolog0.81487265
105MP0005257_abnormal_intraocular_pressure0.80945628
106MP0009931_abnormal_skin_appearance0.80460258
107MP0000733_abnormal_muscle_development0.80404989
108MP0010234_abnormal_vibrissa_follicle0.79588780
109MP0002060_abnormal_skin_morphology0.79542175
110MP0005076_abnormal_cell_differentiation0.79403108
111MP0010030_abnormal_orbit_morphology0.78798012
112MP0009642_abnormal_blood_homeostasis0.78713835
113MP0005584_abnormal_enzyme/coenzyme_acti0.78132802
114MP0002168_other_aberrant_phenotype0.77972484
115MP0002108_abnormal_muscle_morphology0.76895919
116MP0003953_abnormal_hormone_level0.75317995
117MP0002928_abnormal_bile_duct0.74283309
118MP0002295_abnormal_pulmonary_circulatio0.73714713
119MP0010155_abnormal_intestine_physiology0.73679235
120MP0000639_abnormal_adrenal_gland0.73604178
121MP0003448_altered_tumor_morphology0.72554384
122MP0000467_abnormal_esophagus_morphology0.72188066
123MP0005334_abnormal_fat_pad0.71035549
124MP0006082_CNS_inflammation0.70699102
125MP0002970_abnormal_white_adipose0.69028682
126MP0005165_increased_susceptibility_to0.68626071
127MP0001614_abnormal_blood_vessel0.68007611
128MP0010352_gastrointestinal_tract_polyps0.67780744
129MP0001881_abnormal_mammary_gland0.65993369
130MP0000685_abnormal_immune_system0.65899575
131MP0000759_abnormal_skeletal_muscle0.65194216
132MP0000762_abnormal_tongue_morphology0.64267387
133MP0002135_abnormal_kidney_morphology0.63824076
134MP0000462_abnormal_digestive_system0.63451506
135MP0002113_abnormal_skeleton_development0.63083839
136MP0003329_amyloid_beta_deposits0.63060662
137MP0000249_abnormal_blood_vessel0.62829742
138MP0003075_altered_response_to0.62531708
139MP0000358_abnormal_cell_content/0.62464267
140MP0004233_abnormal_muscle_weight0.61009567
141MP0000343_altered_response_to0.60798835
142MP0002971_abnormal_brown_adipose0.60798722
143MP0002136_abnormal_kidney_physiology0.60759989
144MP0009278_abnormal_bone_marrow0.60494643
145MP0002254_reproductive_system_inflammat0.60437224
146MP0002086_abnormal_extraembryonic_tissu0.60356076
147MP0001730_embryonic_growth_arrest0.60183544
148MP0010386_abnormal_urinary_bladder0.59293818
149MP0000747_muscle_weakness0.58821285
150MP0003795_abnormal_bone_structure0.55615328
151MP0000163_abnormal_cartilage_morphology0.54248090
152MP0003656_abnormal_erythrocyte_physiolo0.53821621
153MP0003119_abnormal_digestive_system0.52269915
154MP0001661_extended_life_span0.52086206
155MP0003638_abnormal_response/metabolism_0.52031862
156MP0003115_abnormal_respiratory_system0.51995183
157MP0003045_fibrosis0.51056371
158MP0004130_abnormal_muscle_cell0.49178791

Predicted human phenotypes

RankGene SetZ-score
1Hypoglycemic coma (HP:0001325)4.65100390
2Abnormality of the intrinsic pathway (HP:0010989)4.54570944
3Abnormality of aromatic amino acid family metabolism (HP:0004338)4.49324696
4Deep venous thrombosis (HP:0002625)4.44663251
5Hyperinsulinemic hypoglycemia (HP:0000825)4.08921614
6Xanthomatosis (HP:0000991)4.05899819
7Ketosis (HP:0001946)3.91272237
8Ketoacidosis (HP:0001993)3.91172467
9Intrahepatic cholestasis (HP:0001406)3.88131568
10Hypoglycemic seizures (HP:0002173)3.87432431
11Abnormality of the common coagulation pathway (HP:0010990)3.77906913
12Abnormality of monocarboxylic acid metabolism (HP:0010996)3.75692120
13Vertebral compression fractures (HP:0002953)3.72496345
14Prolonged partial thromboplastin time (HP:0003645)3.38000093
15Late onset (HP:0003584)3.34110048
16Protrusio acetabuli (HP:0003179)3.25659538
17Aortic dissection (HP:0002647)3.17921064
18Fragile skin (HP:0001030)3.11985350
19Abnormality of endocrine pancreas physiology (HP:0012093)3.10574551
20Abnormality of the pancreatic islet cells (HP:0006476)3.10574551
21Abnormality of sulfur amino acid metabolism (HP:0004339)3.07856764
22Gout (HP:0001997)3.06048174
23Complement deficiency (HP:0004431)3.03709389
24Vascular tortuosity (HP:0004948)3.00791753
25Mucopolysacchariduria (HP:0008155)3.00470488
26Urinary glycosaminoglycan excretion (HP:0003541)3.00470488
27Atrophic scars (HP:0001075)2.97511213
28Hyperlipoproteinemia (HP:0010980)2.95267790
29Dysostosis multiplex (HP:0000943)2.93607337
30Hyperglycemia (HP:0003074)2.89724061
31Hyperammonemia (HP:0001987)2.88437377
32Back pain (HP:0003418)2.88231268
33Ankle contracture (HP:0006466)2.84743382
34Arterial tortuosity (HP:0005116)2.84338329
35Aortic aneurysm (HP:0004942)2.82618282
36Hypoalphalipoproteinemia (HP:0003233)2.78951926
37Symptomatic seizures (HP:0011145)2.78419069
38Abnormality of mucopolysaccharide metabolism (HP:0011020)2.76982088
39Abnormality of polysaccharide metabolism (HP:0011012)2.76982088
40Abnormality of glycosaminoglycan metabolism (HP:0004371)2.76982088
41Wormian bones (HP:0002645)2.76266277
42Bladder diverticulum (HP:0000015)2.76058420
43Hypobetalipoproteinemia (HP:0003563)2.74321628
44Premature rupture of membranes (HP:0001788)2.70557866
45Fat malabsorption (HP:0002630)2.63413865
46Hypolipoproteinemia (HP:0010981)2.60724489
47Spinal rigidity (HP:0003306)2.59004029
48Abnormality of dentin (HP:0010299)2.57676906
49Hyperglycinemia (HP:0002154)2.56996948
50Cerebral aneurysm (HP:0004944)2.55906776
51Dilatation of the ascending aorta (HP:0005111)2.55703716
52Protuberant abdomen (HP:0001538)2.55350144
53Conjugated hyperbilirubinemia (HP:0002908)2.51903588
54Achilles tendon contracture (HP:0001771)2.50212246
55Pancreatic islet-cell hyperplasia (HP:0004510)2.49830935
56Soft skin (HP:0000977)2.47827406
57Disproportionate tall stature (HP:0001519)2.46314626
58Cervical subluxation (HP:0003308)2.46000847
59Abnormality of the Achilles tendon (HP:0005109)2.44940330
60Insulin resistance (HP:0000855)2.44424075
61Hyperglycinuria (HP:0003108)2.42281532
62Shallow orbits (HP:0000586)2.40637241
63Abnormality of purine metabolism (HP:0004352)2.40065527
64Follicular hyperkeratosis (HP:0007502)2.39845130
65Increased connective tissue (HP:0009025)2.38603600
66Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.36516773
67Abnormality of the acetabulum (HP:0003170)2.36320119
68Abnormality of glutamine family amino acid metabolism (HP:0010902)2.35783345
69Long toe (HP:0010511)2.35722228
70Abnormality of complement system (HP:0005339)2.34604643
71Elbow flexion contracture (HP:0002987)2.33901502
72Peritonitis (HP:0002586)2.33273114
73Abdominal distention (HP:0003270)2.32341334
74Ulnar bowing (HP:0003031)2.31717557
75Retinal atrophy (HP:0001105)2.28935513
76Generalized aminoaciduria (HP:0002909)2.28792470
77Insulin-resistant diabetes mellitus (HP:0000831)2.27894002
78Mildly elevated creatine phosphokinase (HP:0008180)2.27785151
79Hemorrhage of the eye (HP:0011885)2.27508148
80Spondylolisthesis (HP:0003302)2.27130216
81Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.26585898
82Abnormality of fatty-acid metabolism (HP:0004359)2.25726966
83Flat acetabular roof (HP:0003180)2.24679705
84Increased variability in muscle fiber diameter (HP:0003557)2.24224723
85Malnutrition (HP:0004395)2.23416739
86Hand muscle atrophy (HP:0009130)2.23360936
87Abnormality of dicarboxylic acid metabolism (HP:0010995)2.20966975
88Dicarboxylic aciduria (HP:0003215)2.20966975
89Genu recurvatum (HP:0002816)2.20934427
90Abnormality of serine family amino acid metabolism (HP:0010894)2.20078569
91Abnormality of glycine metabolism (HP:0010895)2.20078569
92Neonatal short-limb short stature (HP:0008921)2.17160889
93Joint hemorrhage (HP:0005261)2.16940696
94Abnormal delivery (HP:0001787)2.16556403
95Abnormality of methionine metabolism (HP:0010901)2.14928591
96Asymmetric septal hypertrophy (HP:0001670)2.14334698
97Abnormality of aspartate family amino acid metabolism (HP:0010899)2.13955126
98Thin bony cortex (HP:0002753)2.13859006
99Hyperacusis (HP:0010780)2.13786370
100Skin nodule (HP:0200036)2.13699641
101Mitral valve prolapse (HP:0001634)2.13588757
102Abnormal tarsal ossification (HP:0008369)2.13459297
103Abnormality of carpal bone ossification (HP:0006257)2.12820891
104Aneurysm (HP:0002617)2.12530614
105Progressive muscle weakness (HP:0003323)2.12168199
106Broad face (HP:0000283)2.11583370
107Abnormality of nucleobase metabolism (HP:0010932)2.11344733
108Abnormal gallbladder physiology (HP:0012438)2.10821288
109Cholecystitis (HP:0001082)2.10821288
110Severe short stature (HP:0003510)2.09982081
111Large for gestational age (HP:0001520)2.09429304
112Premature skin wrinkling (HP:0100678)2.08762549
113Joint laxity (HP:0001388)2.07693288
114Vacuolated lymphocytes (HP:0001922)2.07610325
115Hyperextensible skin (HP:0000974)2.07414676
116Hypercholesterolemia (HP:0003124)2.05376335
117Epidermoid cyst (HP:0200040)2.05070867
118Osteolytic defects of the phalanges of the hand (HP:0009771)2.04911145
119Osteolytic defects of the hand bones (HP:0009699)2.04911145
120Beaking of vertebral bodies (HP:0004568)2.04836983
121Mitral regurgitation (HP:0001653)2.03977570
122Abnormal pancreas size (HP:0012094)2.02325914
123Asymmetry of the thorax (HP:0001555)2.00339456
124Myocardial infarction (HP:0001658)1.99588575
125Abnormality of skeletal muscle fiber size (HP:0012084)1.98870146
126Biconcave vertebral bodies (HP:0004586)1.97488994
127Mitral stenosis (HP:0001718)1.96128898
128Systemic lupus erythematosus (HP:0002725)1.95404633
129Distal lower limb amyotrophy (HP:0008944)1.95288521
130Joint stiffness (HP:0001387)1.94824446
131Type 1 muscle fiber predominance (HP:0003803)1.94604953
132Polycythemia (HP:0001901)1.94021768
133Abnormal enzyme/coenzyme activity (HP:0012379)1.92380327
134Coxa vara (HP:0002812)1.92367509
135Abnormal ossification of hand bones (HP:0005921)1.92150669
136Slender build (HP:0001533)1.91194168
137Turricephaly (HP:0000262)1.90808770
138Pancreatitis (HP:0001733)1.90629701
139J-shaped sella turcica (HP:0002680)1.90471891
140Upper limb amyotrophy (HP:0009129)1.90309764
141Distal upper limb amyotrophy (HP:0007149)1.90309764
142Hepatocellular carcinoma (HP:0001402)1.90288251
143Enlarged kidneys (HP:0000105)1.89891468
144Steatorrhea (HP:0002570)1.89565108
145Hyperbilirubinemia (HP:0002904)1.87151220
146Natal tooth (HP:0000695)1.85838299
147Abnormality of alkaline phosphatase activity (HP:0004379)1.85729286
148Myoglobinuria (HP:0002913)1.85332192
149Nonimmune hydrops fetalis (HP:0001790)1.84833540
150Ectopia lentis (HP:0001083)1.84352512
151Generalized amyotrophy (HP:0003700)1.84290752
152Short nail (HP:0001799)1.84211560
153Cardiovascular calcification (HP:0011915)1.83299007
154Trismus (HP:0000211)1.82033645
155Emphysema (HP:0002097)1.81089464
156Blue sclerae (HP:0000592)1.80843872
157Proximal tubulopathy (HP:0000114)1.80725847
158Stridor (HP:0010307)1.80279229
159Broad metatarsal (HP:0001783)1.78585046
160Abnormal cartilage morphology (HP:0002763)1.78099850
161Nuclear cataract (HP:0100018)1.77497805
162Vascular calcification (HP:0004934)1.77158594
163Distal lower limb muscle weakness (HP:0009053)1.76743023
164Right ventricular cardiomyopathy (HP:0011663)1.76584230
165Advanced eruption of teeth (HP:0006288)1.76140724
166Cupped ribs (HP:0000887)1.72572059
167Breech presentation (HP:0001623)1.70421597
168Obstructive sleep apnea (HP:0002870)1.66813645
169Interstitial pulmonary disease (HP:0006530)1.66136127
170Ankyloglossia (HP:0010296)1.65914789
171Syringomyelia (HP:0003396)1.64574651
172Spinal cord lesions (HP:0100561)1.64574651
173Venous abnormality (HP:0002624)1.63950299

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN16.01983445
2TRIB34.84118253
3BCKDK4.03867322
4PKN23.17992815
5SMG12.92492244
6INSRR2.67764921
7SIK12.64533869
8PRPF4B2.42805529
9TAOK32.20862884
10PTK62.01795821
11PRKD32.01277526
12LATS11.94268542
13FGFR41.93806758
14NME21.91955498
15PASK1.82013560
16FLT31.75362640
17IRAK31.74084169
18MAPK151.70767300
19PDGFRA1.70364393
20MAP3K101.68780595
21EEF2K1.66487073
22PTK21.63248958
23MAP3K31.47625429
24EPHA21.42239726
25ICK1.40493105
26PIK3CG1.35434814
27DDR21.33139188
28RIPK11.32471920
29FRK1.29408424
30PDK31.29092658
31PDK41.29092658
32DYRK1B1.24784707
33TESK11.24408366
34MTOR1.21370901
35MAPKAPK31.17417992
36TTN1.17174677
37MAP3K21.16324457
38TAOK11.15783667
39KSR21.14267309
40MAP2K21.11169670
41SCYL21.10359630
42MET1.08527244
43WNK41.07481868
44KDR1.07447247
45MAP3K111.05359735
46STK38L1.03785189
47CDC42BPA0.99242358
48MAPK110.98896827
49TESK20.98413765
50LMTK20.94440702
51MAP3K130.92775944
52FER0.91261205
53MAP2K30.89454040
54HIPK20.85430871
55EPHA30.83435775
56BMX0.81212389
57PRKG20.80364775
58CAMK1D0.80361362
59MAP3K140.78848621
60FGFR30.77869837
61PAK20.77722620
62ARAF0.77171569
63PRKCI0.76078881
64NEK90.74323130
65PDK20.74054953
66MAP3K10.72753938
67TGFBR20.72292833
68MAP3K60.71031772
69EIF2AK30.70837883
70LATS20.68714685
71TRPM70.67541711
72EPHB10.65893747
73SIK30.64061021
74JAK30.63697544
75MST1R0.63450674
76RIPK40.62829939
77LRRK20.62573063
78STK380.61930524
79ILK0.61740146
80TAOK20.60140388
81CAMK1G0.59667293
82TYK20.59176873
83RET0.56803432
84CDK70.56571041
85MARK20.56084536
86PTK2B0.55971927
87CDK40.55593097
88MOS0.54983916
89CLK10.54534841
90PAK40.53246929
91BRAF0.53144778
92IRAK10.52851943
93CDK120.51354381
94MELK0.50694120
95AKT30.50306956
96MAPKAPK20.50289682
97EIF2AK10.49514125
98PRKD10.48223943
99ZAP700.48135521
100PINK10.47372845
101PDGFRB0.46948126
102RPS6KB20.46493453
103RPS6KA40.46462540
104LIMK10.46013100
105DMPK0.45779388
106EPHB20.45689570
107JAK10.44861491
108MAP3K70.44544317
109MAPK70.43921189
110PRKD20.42533569
111MAP2K10.42021036
112JAK20.41694539
113MYLK0.41529563
114PDK10.41047675
115IRAK40.40040832
116PRKAA10.39967075
117PAK30.38468551
118MAP3K80.37139896
119PAK10.37104567
120CAMKK10.36508079
121CDK90.35452098
122RPS6KA20.35066795
123RPS6KL10.34536657
124RPS6KC10.34536657
125CDK60.34362696
126ERBB40.33213491
127TBK10.32705890
128FGFR10.32477299
129GSK3A0.32369379
130NEK20.31128596
131NTRK10.29715575
132PRKCH0.27123345
133BRD40.27116189
134PIM20.26004427
135STK100.24630016
136PDPK10.23886196
137TIE10.22809804
138DAPK30.21310173

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.22583335
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.96509619
3Selenocompound metabolism_Homo sapiens_hsa004502.76017268
4Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.69088410
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.45310017
6Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.37049596
7Protein export_Homo sapiens_hsa030602.34616305
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.32881638
9Fat digestion and absorption_Homo sapiens_hsa049752.30171128
10Fatty acid degradation_Homo sapiens_hsa000712.23753856
11Tryptophan metabolism_Homo sapiens_hsa003802.22147766
12Nitrogen metabolism_Homo sapiens_hsa009102.09392876
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.07389441
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.04728570
15Arginine biosynthesis_Homo sapiens_hsa002202.03965769
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.86344896
17Complement and coagulation cascades_Homo sapiens_hsa046101.83988456
182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.82366684
19Folate biosynthesis_Homo sapiens_hsa007901.81023273
20Propanoate metabolism_Homo sapiens_hsa006401.76246056
21Focal adhesion_Homo sapiens_hsa045101.72839971
22Chronic myeloid leukemia_Homo sapiens_hsa052201.72814530
23Sulfur metabolism_Homo sapiens_hsa009201.71432784
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.57862516
25Fatty acid metabolism_Homo sapiens_hsa012121.52342665
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.52126225
27Acute myeloid leukemia_Homo sapiens_hsa052211.51049519
28Biosynthesis of amino acids_Homo sapiens_hsa012301.50962444
29PPAR signaling pathway_Homo sapiens_hsa033201.47577261
30Pentose and glucuronate interconversions_Homo sapiens_hsa000401.44759671
31Protein digestion and absorption_Homo sapiens_hsa049741.42510244
32Pyruvate metabolism_Homo sapiens_hsa006201.40390007
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39238523
34Starch and sucrose metabolism_Homo sapiens_hsa005001.38670816
35Small cell lung cancer_Homo sapiens_hsa052221.38472848
36N-Glycan biosynthesis_Homo sapiens_hsa005101.38244667
37Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.38055481
38Amoebiasis_Homo sapiens_hsa051461.37507042
39Glycosaminoglycan degradation_Homo sapiens_hsa005311.36056880
40Lysine degradation_Homo sapiens_hsa003101.32531836
41Peroxisome_Homo sapiens_hsa041461.30520150
42Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.30502686
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.29906309
44Galactose metabolism_Homo sapiens_hsa000521.29102989
45Pancreatic cancer_Homo sapiens_hsa052121.29067014
46Butanoate metabolism_Homo sapiens_hsa006501.28757670
47Carbon metabolism_Homo sapiens_hsa012001.26143563
48Proteoglycans in cancer_Homo sapiens_hsa052051.25831806
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.24839591
50Thyroid cancer_Homo sapiens_hsa052161.23471181
51Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.20446611
52Bile secretion_Homo sapiens_hsa049761.19614066
53Non-small cell lung cancer_Homo sapiens_hsa052231.19363468
54Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.17272206
55One carbon pool by folate_Homo sapiens_hsa006701.15916690
56beta-Alanine metabolism_Homo sapiens_hsa004101.14683244
57Pancreatic secretion_Homo sapiens_hsa049721.14432745
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.13162828
59VEGF signaling pathway_Homo sapiens_hsa043701.12755113
60Other glycan degradation_Homo sapiens_hsa005111.10153419
61Phenylalanine metabolism_Homo sapiens_hsa003601.10008838
62Arginine and proline metabolism_Homo sapiens_hsa003301.09864372
63Glycerolipid metabolism_Homo sapiens_hsa005611.08531648
64Fructose and mannose metabolism_Homo sapiens_hsa000511.06750596
65Sulfur relay system_Homo sapiens_hsa041221.05120347
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.03036521
67Histidine metabolism_Homo sapiens_hsa003400.98615099
68Notch signaling pathway_Homo sapiens_hsa043300.98430695
69Vitamin digestion and absorption_Homo sapiens_hsa049770.95775912
70Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93594413
71Adherens junction_Homo sapiens_hsa045200.93219660
72Leukocyte transendothelial migration_Homo sapiens_hsa046700.91966616
73TNF signaling pathway_Homo sapiens_hsa046680.91418942
74Lysosome_Homo sapiens_hsa041420.90949576
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.90635346
76Prostate cancer_Homo sapiens_hsa052150.90246871
77Hepatitis C_Homo sapiens_hsa051600.90197922
78Cyanoamino acid metabolism_Homo sapiens_hsa004600.88442968
79ABC transporters_Homo sapiens_hsa020100.88282721
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86555845
81Insulin resistance_Homo sapiens_hsa049310.86497606
82Toxoplasmosis_Homo sapiens_hsa051450.86242353
83Endometrial cancer_Homo sapiens_hsa052130.86088191
84Malaria_Homo sapiens_hsa051440.84826407
85Hepatitis B_Homo sapiens_hsa051610.83179643
86Renal cell carcinoma_Homo sapiens_hsa052110.81454002
87Pertussis_Homo sapiens_hsa051330.80452393
88Shigellosis_Homo sapiens_hsa051310.79590509
89Insulin secretion_Homo sapiens_hsa049110.78540524
90Caffeine metabolism_Homo sapiens_hsa002320.78360589
91Glucagon signaling pathway_Homo sapiens_hsa049220.78103814
92Pentose phosphate pathway_Homo sapiens_hsa000300.77743079
93Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76494520
94Chemical carcinogenesis_Homo sapiens_hsa052040.76376359
95Neurotrophin signaling pathway_Homo sapiens_hsa047220.75811119
96Tyrosine metabolism_Homo sapiens_hsa003500.75528079
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75395457
98Glioma_Homo sapiens_hsa052140.75106574
99mTOR signaling pathway_Homo sapiens_hsa041500.74954223
100Apoptosis_Homo sapiens_hsa042100.73869111
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73226778
102Renin-angiotensin system_Homo sapiens_hsa046140.73107588
103Staphylococcus aureus infection_Homo sapiens_hsa051500.72737693
104MicroRNAs in cancer_Homo sapiens_hsa052060.72699010
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70981141
106B cell receptor signaling pathway_Homo sapiens_hsa046620.70688708
107Retinol metabolism_Homo sapiens_hsa008300.70523711
108Influenza A_Homo sapiens_hsa051640.69083643
109Toll-like receptor signaling pathway_Homo sapiens_hsa046200.68810844
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.67713875
111Osteoclast differentiation_Homo sapiens_hsa043800.66587237
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65365703
113HIF-1 signaling pathway_Homo sapiens_hsa040660.64034735
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62432476
115NF-kappa B signaling pathway_Homo sapiens_hsa040640.62164220
116Endocytosis_Homo sapiens_hsa041440.60112722
117Prolactin signaling pathway_Homo sapiens_hsa049170.59975637
118Thyroid hormone synthesis_Homo sapiens_hsa049180.58661417
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.58187896
120Vibrio cholerae infection_Homo sapiens_hsa051100.56001941
121Sphingolipid metabolism_Homo sapiens_hsa006000.55880016
122HTLV-I infection_Homo sapiens_hsa051660.54938410
123ErbB signaling pathway_Homo sapiens_hsa040120.53120290
124Steroid hormone biosynthesis_Homo sapiens_hsa001400.52316624
125Estrogen signaling pathway_Homo sapiens_hsa049150.51575686
126Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.51451296
127Prion diseases_Homo sapiens_hsa050200.51422801
128Salmonella infection_Homo sapiens_hsa051320.51414459
129Bladder cancer_Homo sapiens_hsa052190.50127504
130GnRH signaling pathway_Homo sapiens_hsa049120.49796636
131Type II diabetes mellitus_Homo sapiens_hsa049300.47341480
132Phospholipase D signaling pathway_Homo sapiens_hsa040720.46733330
133Linoleic acid metabolism_Homo sapiens_hsa005910.46608436
134Viral carcinogenesis_Homo sapiens_hsa052030.45141759
135Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45022674
136Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44160921
137ECM-receptor interaction_Homo sapiens_hsa045120.42786096
138Adipocytokine signaling pathway_Homo sapiens_hsa049200.42150328
139Metabolic pathways_Homo sapiens_hsa011000.39590552
140Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38945879
141Glutathione metabolism_Homo sapiens_hsa004800.36765928
142Fatty acid biosynthesis_Homo sapiens_hsa000610.35988303
143Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34859550
144Insulin signaling pathway_Homo sapiens_hsa049100.34356395
145Central carbon metabolism in cancer_Homo sapiens_hsa052300.33049719
146AMPK signaling pathway_Homo sapiens_hsa041520.31568723
147Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.29962656
148Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.28601988
149Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.28041635
150Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27020122
151Glycerophospholipid metabolism_Homo sapiens_hsa005640.25902589
152Vitamin B6 metabolism_Homo sapiens_hsa007500.22368755
153Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.20492728

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »